Page last updated: 2024-08-17

methionine and Obesity

methionine has been researched along with Obesity in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (8.89)	18.7374
1990's	7 (7.78)	18.2507
2000's	12 (13.33)	29.6817
2010's	39 (43.33)	24.3611
2020's	24 (26.67)	2.80

Authors

Authors	Studies
Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y	1
Chen, J; Dong, Z; Gao, L; Li, F; Lin, J; Lin, Y; Ren, S; Sun, P; Wang, S; Wang, Z; Wu, B; Yang, Z	1
Kalso, E; Lötsch, J; Mäntyselkä, P; Miettinen, T; Nieminen, AI	1
Johnson, JE; Plummer, JD	1
Jeon, MS; Kim, M; Li, J; Liu, Z; Peng, H; Wang, X; Wu, J; Xie, L; Xu, H; Zhang, KK	1
Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A	1
Bakers, FCH; Brouwers, MCGJ; Dagnelie, PC; Elshorbagy, AK; Eussen, SJPM; Jansen, JFA; Kooi, ME; Kusters, YHAM; Meex, SJR; Olsen, T; Refsum, H; Retterstøl, K; Schalkwijk, CG; Stehouwer, CDA; Tore, EC; van Greevenbroek, MMJ; Vinknes, KJ	1
Feng, C; Ge, Y; Jiang, Y; Le, G; Li, S; Shi, Y; Tang, X	1
Ables, GP; Bastani, NE; Cooke, D; Kožich, V; Malloy, VL; Mansilla, W; Mattocks, DAL; Midya, V; Nichenametla, SN; Olsen, T; Pavlíková, M; Refsum, H; Richie, JP; Shoveller, AK; Sokolová, J; Turner, C; Vinknes, KJ; Øvrebø, B	1
Dam, J; Hosoi, T; Jockers, R; Kuriya, K; Ozawa, K; Preninka, AI; Yanase, Y; Yazawa, K; Yoshii, M	1
He, X; Huang, X; Ji, N; Liu, M; Sun, T; Wang, J	1
Buechler, C; Girke, P; Haberl, EM; Krautbauer, S; Liebisch, G; Mages, W; Pohl, R; Rein-Fischboeck, L	1
Bastani, NE; Dagnelie, PC; Elshorbagy, AK; Eussen, SJPM; Grootswagers, P; Kožich, V; Olsen, T; Refsum, H; Retterstøl, K; Stehouwer, CD; Stolt, ETK; Tore, EC; van Greevenbroek, MMJ; Vinknes, KJ	1
Guo, Z; Li, Y; Liang, Y; Liu, Y; Qu, L; Sun, G; Wang, H; Wang, Y; Zhang, C	1
Amiel, A; Aurich, MK; Canlet, C; Dardevet, D; Debrauwer, L; Jourdan, F; Polakof, S; Poupin, N; Rémond, D; Savary-Auzeloux, I; Thiele, I; Tremblay-Franco, M	1
Feng, C; Ge, Y; Han, L; Jiang, Y; Le, G; Li, B; Shi, Y; Wu, G; Yang, Y	1
Kitada, M; Koya, D; Monno, I; Ogura, Y; Xu, J	1
Elshorbagy, AK; Graham, I; Refsum, H	1
Hu, L; Ma, Q; Meng, Q; Shan, A; Shao, C; Sun, Y; Zhou, X; Zhu, J	1
Chu, C; Liu, X; Liu, Z; Ren, B; Wang, L; Wu, J; Zhang, Q; Zhao, W; Zhao, Z	1
Annicchiarico-Petruzzelli, M; Candi, E; Cardillo, C; Di Daniele, N; Gentileschi, P; Lena, AM; Melino, G; Piro, MC; Rodia, G; Rovella, V; Sica, G; Tesauro, M	1
Acar, MB; Ayaz-Güner, Ş; Di Bernardo, G; Galderisi, U; Güner, H; Murat, A; Özcan, S; Peluso, G	1
Degens, H; Fokin, A; Swaminathan, A; Venckūnas, T	1
Fang, H; Forney, LA; Gettys, TW; Ghosh, S; Sims, LC; Stone, KP; Vincik, L	1
Abe, A; Miyajima, K; Nakae, D; Nakane, S; Ogawa, S; Sano, R; Suzuki-Kemuriyama, N; Uno, K; Watanabe, A; Yuki, M	1
Anthony, TG; Bargoud, AR; Gettys, TW; Hamilton, KL; Jonsson, WO; Kimball, SR; Miller, BF; Mirek, ET; Peelor, FF; Pettit, AP; Wang, Y; Wek, RC	1
Engin, A; Engin, AB	1
Forney, LA; Gettys, TW; Stone, KP; Wanders, D	1
Brinkman, JA; Cryns, VL; Cummings, NE; Kimple, ME; Lamming, DW; Miller, BR; Sherman, DS; Tomasiewicz, JL; Wisinski, JA; Yang, SE; Yu, D	1
Cho, S; Park, KW; Yang, J	1
Cheng, X; Guo, H; Le, G; Shi, Y; Sun, J; Tang, X; Wang, Y; Wu, G; Yang, Y; Zhang, J	1
Le, G; Luo, T; Shi, Y; Sun, J; Wang, Y; Wu, G; Xu, Y; Yang, Y	1
Liao, LM; Lu, J; Michels, KA; Pfeiffer, RM; Trabert, B	1
Eder, K; Gessner, DK; Liebisch, G; Meyer, S; Most, E; Ringseis, R; Wen, G; Zorn, H	1
Jiang, Y; Le, G; Li, B; Luo, T; Shi, Y; Sun, J; Xu, Y; Yang, Y; Zhang, Y	1
Gao, Q; Jiang, Y; Le, G; Luo, T; Shi, Y; Sun, J; Wu, G; Xu, Y; Yang, Y	1
Cai, YY; Li, J; Li, P; Liu, BL; Liu, Q; Pan, A; Qi, LW; Yang, L; Zhang, WS	1
Aguilar-Salinas, CA; Bojalil, R; Canizales-Quinteros, S; Domínguez-López, A; Guillén-Pineda, LE; Gutiérrez-Vidal, R; Jacobo-Albavera, L; Larrieta-Carrasco, E; León-Mimila, P; López-Contreras, BE; Mejía-Domínguez, AM; Méndez-Sánchez, N; Romero-Hidalgo, S; Sánchez-Muñoz, F; Villamil-Ramírez, H; Villarreal-Molina, T	1
Ables, GP; Caliendo, NS; Malloy, VL; Mattocks, DA; Orentreich, DS; Orentreich, N; Perrone, CE	1
Aibara, D; Gonzalez, FJ; Matsuo, K; Matsusue, K; Takiguchi, S; Yamano, S	1
Canet, MJ; Cherrington, NJ; Clarke, JD; Dzierlenga, AL; Hardwick, RN; Lake, AD	1
Antonini, SR; Barbieri, MA; Bettiol, H; Bueno, AC; de Castro, M; Elias Junior, J; Foss-Freitas, MC; Martins, CS; Miranda, W; Scherer, PE; Sun, K; Tao, C	1
Claudel, T; Hoefler, G; Jha, P; Knopf, A; Koefeler, H; Lackner, C; Mueller, M; Trauner, M	1
Albano, E; Bena, S; Bozzola, C; Bugianesi, E; Jindal, A; Kusters, D; Locatelli, I; McArthur, S; Parola, M; Paternostro, C; Perretti, M; Reutelingsperger, C; Sutti, S; Vacchiano, M	1
Baud, V; Billot, K; Collin de l'Hortet, A; Fauveau, V; Gilgenkrantz, H; Guidotti, JE; Helmy, N; Prip-Buus, C; Vons, C; Zerrad-Saadi, A; Ziol, M	1
Adamski, J; Grallert, H; Harder, U; Hellmuth, C; Illig, T; Knop, C; Koletzko, B; Lass, N; Peissner, W; Prehn, C; Reinehr, T; Wahl, S; Wang-Sattler, R; Wolters, B; Yu, Z	1
Azuma, T; Hoshi, N; Kawano, Y; Minami, A; Nishiumi, S; Terashima, Y; Yoshida, M	1
Bykowska, AS; Delibegovic, M; Gettys, TW; Grant, L; Król, E; Lees, EK; Mody, N; Moncur, E; Shearer, K; Wyse, C	1
Calderon, LF; Gettys, TW; Scherer, PE; Spurgin, SB; Stone, KP; Wanders, D	1
He, L; Wan, D; Wu, G; Wu, X; Yang, H; Yao, K; Yin, Y; Zhou, X	1
Jiao, F; Ma, Y; Ou, H; Yan, X; Yan, Z; Yu, Y; Yue, Z; Zhu, X	1
Burk, DH; Forney, LA; Gettys, TW; Pierse, A; Stone, KP; Wanders, D	1
Bekaert, B; Devlieger, R; Duca, RC; Freson, K; Ghosh, M; Godderis, L; Huybrechts, I; Koppen, G; Langie, SAS; Pauwels, S; Truijen, I	1
Agboola, KM; Charlton, P; Choi, SS; Diehl, AM; Guy, CD; Jung, Y; Karaca, FG; Omenetti, A; Pereira, TA; Pollard, J; Stone, WC; Syn, WK; Teaberry, V; Witek, RP	1
Boeing, H; Döring, F; Fisher, E; Grallert, H; Illig, T; Klapper, M; Pfäfflin, A; Schrezenmeir, J	1
Black, C; Boudreau, A; Gettys, TW; Hasek, BE; Henagan, TM; Huypens, P; Krajcik, RA; Lenard, NR; Malloy, VL; Orentreich, N; Plaisance, EP; Shin, J; Stewart, LK	1
Bachmair, EM; Boekschoten, MV; Brennan, L; Coort, SL; Daniel, H; Evelo, C; Gibney, MJ; Keijer, J; Kleemann, R; McLoughlin, GA; Muller, M; Roos, Bd; Rubio-Aliaga, I; Sailer, M; van Erk, M; van Schothorst, EM	1
Boudreau, A; Cefalu, WT; Gettys, TW; Greenway, FL; Hill, KL; Johnson, WD; Krajcik, RA; Orentreich, N; Perrone, CE; Plaisance, EP	1
Elshorbagy, AK; Kozich, V; Refsum, H; Smith, AD	1
Elias, M; Gardikiotes, K; Gottstein, J; Green, RM; Rinella, ME; Siddiqui, MS	1
Borovecki, F; Curkovic, M; Dodig-Curkovic, K; Nikolac, M; Pivac, N; Skledar, M	1
Camporez, JP; Eisenbarth, SC; Elinav, E; Flavell, RA; Gordon, JI; Hao, L; Henao-Mejia, J; Hoffman, HM; Jin, C; Jurczak, MJ; Kau, AL; Mehal, WZ; Shulman, GI; Strowig, T; Thaiss, CA	1
Adams, SH	1
Ables, GP; Orentreich, D; Orentreich, N; Perrone, CE	1
Hada, N; Ito, T; Katsume, A; Matsumoto, M; Sakamaki, Y; Shiga, T; Sudoh, M; Tanaka, C; Uno, A	1
Astrup, A; Dyerberg, J; Haulrik, N; Skov, AR; Stender, S; Toubro, S	1
Goodman, KJ; Hadengue, A; Jordan, M; Leandro, G; Marinescu, O; Negro, F; Rubbia-Brandt, L; Spahr, L	1
Green, RM; Malladi, P; Melin-Aldana, H; Pan, X; Paul, R; Sahai, A; Whitington, PF	1
Brown, JL; Hirose, R; Jackman, M; Liu, T; Maher, JJ; Niemann, CU; Roberts, JP; Serkova, NJ	1
Hwang, PH; Jo, DS; Kim, SL; Kim, SY; Lee, DY; Lee, KH	1
Lam, JB; Lam, KS; Lam, MC; Leung, PT; Wang, Y; Xu, A; Zhou, M	1
Akahori, H; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa, N; Misu, H; Nakanuma, Y; Ota, T; Sakurai, M; Takamura, T; Uno, M; Zen, Y	1
Bhanot, S; Diehl, AM; Huang, J; Li, YX; McCall, S; Monia, BP; Pandey, SK; Yamaguchi, K; Yang, L; Yu, XX	1
Copple, BL; Gyamfi, M; He, L; Wan, YJ; Wortham, M	1
Gougeon, R; Marliss, EB; Pencharz, PB	1
Bauer, TL; Caro, JF; Considine, EL; Considine, RV; Kolaczynski, JW; Moore, JH; Nyce, MR; Ohannesian, JP; Opentanova, I; Williams, CJ; Zhang, P	1
Hoffman, RM	1
Blom, HJ; Kluijtmans, LA; Kok, FJ; Kruyssen, DA; Refsum, H; Ueland, PM; Verhoef, P	1
Eris, T; Katta, V; Liu, JL; Lu, HS; Lu, KV; Narhi, LO; Westcott, KR	1
Albu, J; Allison, DB; Burn, P; Chin, W; Deng, N; Duprat, L; Fisher, SL; Franco, LS; Gu, W; Heymsfield, S; Kissebah, A; Kleyn, PW; Lee, J; Maruti, S; Nathan, J; Pi-Sunyer, FX; Tu, Z; Yagaloff, KA	1
Aigner, R; Borkenstein, M; Erwa, W; Gallistl, S; Sudi, KM	1
Brummel, MC; Cho, ES; Printen, KJ; Stegink, LD	1
Butenandt, O	1
Cama, A; de la Luz Sierra, M; Gorden, P; Imperato-McGinley, J; Kadowaki, T; Ottini, L; Taylor, SI	1
Blackshear, PJ; Hung, MC; Kennington, EA; Orth, DN; Rosner, MR; Stumpo, DJ; Thompson, KL; Tuttle, JS	1
Hellman, B; Sehlin, J; Täljedal, IB	1
Owen, OE; Pozefsky, T; Sapir, DG; Walser, M	1
Dominguez, JM; Gallina, DL	1
Combs, GF; Khalil, AA; Thomas, OP	1
Binder, HJ; Herskovic, T; Spencer, RP; Spiro, HM	1

Reviews

7 review(s) available for methionine and Obesity

Article	Year
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application. International journal of molecular sciences, 2021, Oct-22, Volume: 22, Issue:21 Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction	2021
The Interactions Between Kynurenine, Folate, Methionine and Pteridine Pathways in Obesity. Advances in experimental medicine and biology, 2017, Volume: 960 Topics: Animals; Folic Acid; Humans; Inflammation; Kynurenine; Methionine; Obesity; Pteridines; Signal Transduction	2017
Sensing and signaling mechanisms linking dietary methionine restriction to the behavioral and physiological components of the response. Frontiers in neuroendocrinology, 2018, Volume: 51 Topics: Animals; Diet; Fibroblast Growth Factors; Insulin Resistance; Lipid Metabolism; Liver; Male; Methionine; Obesity	2018
Methionine restriction on lipid metabolism and its possible mechanisms. Amino acids, 2016, Volume: 48, Issue:7 Topics: Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lipid Metabolism; Methionine; Obesity	2016
Cysteine and obesity. Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:3 Topics: Body Mass Index; Body Weight; Cysteine; Female; Humans; Male; Methionine; Obesity; Risk Factors	2012
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. Advances in nutrition (Bethesda, Md.), 2011, Volume: 2, Issue:6 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine	2011
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease. Human cell, 1997, Volume: 10, Issue:1 Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins	1997

Trials

3 trial(s) available for methionine and Obesity

Article	Year
Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:5 Topics: Adipose Tissue; Biomarkers; Body Composition; Cohort Studies; Cystine; Diet; Dietary Fats; Double-Blind Method; Energy Metabolism; Fats; Female; Glucose; Humans; Insulin Resistance; Kinetics; Liver; Male; Metabolic Syndrome; Methionine; Middle Aged; Obesity; Oxidation-Reduction; Waist Circumference	2011
Effect of protein and methionine intakes on plasma homocysteine concentrations: a 6-mo randomized controlled trial in overweight subjects. The American journal of clinical nutrition, 2002, Volume: 76, Issue:6 Topics: Adolescent; Adult; Analysis of Variance; Body Weight; Diet; Diet, Protein-Restricted; Dietary Proteins; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Obesity; Vitamin B 12	2002
Whole-body protein turnover in obese subjects during two very low energy diets of differing amino acid composition. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1995, Volume: 19, Issue:10 Topics: Adult; Amino Acids; Analysis of Variance; Body Mass Index; Caseins; Collagen; Diet, Protein-Restricted; Energy Metabolism; Female; Humans; Male; Methionine; Middle Aged; Nitrogen; Nitrogen Isotopes; Obesity; Plant Proteins, Dietary; Proteins; Soybean Proteins; Tryptophan; Urea	1995

Other Studies

80 other study(ies) available for methionine and Obesity

Article	Year
PPAR-γ integrates obesity and adipocyte clock through epigenetic regulation of Theranostics, 2022, Volume: 12, Issue:4 Topics: Acetyl Coenzyme A; Adipocytes; Animals; ARNTL Transcription Factors; Circadian Rhythm; CLOCK Proteins; Epigenesis, Genetic; Gene Expression Regulation; Glutamine; Humans; Methionine; Mice; Obesity; PPAR gamma	2022
Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes. International journal of molecular sciences, 2022, May-03, Volume: 23, Issue:9 Topics: Adenosine Monophosphate; Biomarkers; Chronic Pain; Cysteine; Female; Humans; Machine Learning; Metabolome; Metabolomics; Methionine; NAD; Obesity; Phenotype; Sleep Wake Disorders	2022
Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to continuous methionine restriction. Aging cell, 2022, Volume: 21, Issue:6 Topics: Adiponectin; Animals; Diet; Insulin-Like Growth Factor I; Methionine; Mice; Obesity	2022
Maternal One-Carbon Supplement Reduced the Risk of Non-Alcoholic Fatty Liver Disease in Male Offspring. Nutrients, 2022, Jun-19, Volume: 14, Issue:12 Topics: Animals; Carbon; Diet, High-Fat; Dietary Supplements; Epigenesis, Genetic; Female; Humans; Liver; Male; Maternal Nutritional Physiological Phenomena; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Prenatal Exposure Delayed Effects	2022
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan. Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:8 Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine	2022
Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European journal of nutrition, 2023, Volume: 62, Issue:2 Topics: Adipose Tissue; Adiposity; Amino Acids, Sulfur; Body Mass Index; Chromatography, Liquid; Cross-Sectional Studies; Cysteine; Female; Humans; Intra-Abdominal Fat; Liver Diseases; Male; Methionine; Obesity; Tandem Mass Spectrometry	2023
Methionine Restriction Improves Cognitive Ability by Alleviating Hippocampal Neuronal Apoptosis through H19 in Middle-Aged Insulin-Resistant Mice. Nutrients, 2022, Oct-26, Volume: 14, Issue:21 Topics: Animals; Apoptosis; Cognition; Diet, High-Fat; Hippocampus; Hydrogen Peroxide; Insulin; Methionine; Mice; Mice, Inbred C57BL; Obesity; Racemethionine	2022
Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism. Aging cell, 2022, Volume: 21, Issue:12 Topics: Amino Acids, Sulfur; Animals; Cross-Sectional Studies; Cysteine; Female; Humans; Lipid Metabolism; Male; Methionine; Mice; Obesity; Serine	2022
Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress. PloS one, 2022, Volume: 17, Issue:12 Topics: Cysteine; Endoplasmic Reticulum Stress; Homocysteine; Humans; Leptin; Methionine; Neuroblastoma; Obesity; Receptors, Leptin; STAT3 Transcription Factor	2022
[Plasma amino acids levels in 1859 physical examination subjects in Hangzhou City in 2020]. Wei sheng yan jiu = Journal of hygiene research, 2022, Volume: 51, Issue:6 Topics: Alanine; Amino Acids; Chromatography, Liquid; Female; Humans; Leucine; Male; Methionine; Middle Aged; Obesity; Overweight; Tandem Mass Spectrometry	2022
Lower adiposity does not protect beta-2 syntrophin null mice from hepatic steatosis and inflammation in experimental non-alcoholic steatohepatitis. Gene, 2023, Apr-05, Volume: 859 Topics: Adiposity; Animals; Cholesterol Esters; Choline; Disease Models, Animal; Fatty Acid Synthases; Fatty Acids; Inflammation; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity	2023
The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study. The Journal of nutrition, 2023, Volume: 153, Issue:7 Topics: Amino Acids, Sulfur; Cardiovascular Diseases; Cross-Sectional Studies; Cystathionine; Cysteine; Diabetes Mellitus, Type 2; Diet; Female; Homocysteine; Humans; Methionine; Obesity; Taurine	2023
Dietary intakes of methionine, threonine, lysine, arginine and histidine increased risk of type 2 diabetes in Chinese population: does the mediation effect of obesity exist? BMC public health, 2023, 08-15, Volume: 23, Issue:1 Topics: Amino Acids; Arginine; Diabetes Mellitus, Type 2; Diet; East Asian People; Histidine; Humans; Lysine; Male; Methionine; Obesity; Racemethionine; Risk Factors; Threonine	2023
Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig. Scientific reports, 2019, 08-29, Volume: 9, Issue:1 Topics: Animals; Arteries; Disease Models, Animal; Fatty Acids; Female; Humans; Insulin; Intestines; Liver; Metabolomics; Methionine; Obesity; Swine; Swine, Miniature; Threonine; Veins	2019
Dietary methionine restriction improves the impairment of cardiac function in middle-aged obese mice. Food & function, 2020, Feb-26, Volume: 11, Issue:2 Topics: Animals; Body Weight; Cardiomegaly; Diet; Energy Metabolism; Homocysteine; Hydrogen Sulfide; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Myocardium; Obesity; Oxidative Stress	2020
Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes. Aging, 2020, 03-06, Volume: 12, Issue:5 Topics: Animals; Autophagy; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Protein-Restricted; Disease Models, Animal; Female; Kidney; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Obesity; Rats; Rats, Wistar	2020
Body mass index determines the response of plasma sulfur amino acids to methionine loading. Biochimie, 2020, Volume: 173 Topics: Adult; Amino Acids, Sulfur; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Male; Methionine; Middle Aged; Obesity; Overweight	2020
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice. Journal of agricultural and food chemistry, 2020, Apr-29, Volume: 68, Issue:17 Topics: Adipose Tissue, Brown; Animals; Anti-Obesity Agents; Diet, High-Fat; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lysine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Threonine; Uncoupling Protein 1	2020
Methionine restriction alleviates high-fat diet-induced obesity: Involvement of diurnal metabolism of lipids and bile acids. Biochimica et biophysica acta. Molecular basis of disease, 2020, 11-01, Volume: 1866, Issue:11 Topics: Animals; Bile Acids and Salts; Blotting, Western; Circadian Rhythm; Diet, High-Fat; Fibroblast Growth Factors; Immunohistochemistry; Lipid Metabolism; Lipids; Methionine; Mice; Mice, Inbred C57BL; Obesity; Real-Time Polymerase Chain Reaction; Tandem Mass Spectrometry	2020
Free-amino acid metabolic profiling of visceral adipose tissue from obese subjects. Amino acids, 2020, Volume: 52, Issue:8 Topics: Adipose Tissue; Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Chromatography, Liquid; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Histidine; Humans; Intra-Abdominal Fat; Male; Metabolome; Metabolomics; Methionine; Middle Aged; Obesity; Tandem Mass Spectrometry; Taurine; Tryptophan; Young Adult	2020
Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue. Aging, 2020, 12-27, Volume: 12, Issue:24 Topics: Aging; Animals; Diet, High-Fat; Granzymes; HMGB1 Protein; Inflammation; Interleukin-1; Intra-Abdominal Fat; Leptin; Mesenchymal Stem Cells; Methionine; Mice; Obesity; Proteome; Proto-Oncogene Proteins c-met; Receptor, Fibroblast Growth Factor, Type 2; RNA Precursors; RNA Processing, Post-Transcriptional; Secretory Vesicles; Signal Transduction; Transforming Growth Factor beta; Vascular Endothelial Growth Factor Receptor-2; Wnt Signaling Pathway	2020
Methionine restriction plus overload improves skeletal muscle and metabolic health in old mice on a high fat diet. Scientific reports, 2021, 01-13, Volume: 11, Issue:1 Topics: Aging; Animals; Diet, High-Fat; Male; Methionine; Mice; Muscle, Skeletal; Obesity; Physical Conditioning, Animal	2021
Hepatic Nutrients, 2021, May-24, Volume: 13, Issue:6 Topics: Adiposity; Animals; Body Weight; Energy Metabolism; Fibroblast Growth Factors; Genotype; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Obesity; Phenotype	2021
Nonobese mice with nonalcoholic steatohepatitis fed on a choline-deficient, l-amino acid-defined, high-fat diet exhibit alterations in signaling pathways. FEBS open bio, 2021, Volume: 11, Issue:11 Topics: Amino Acids; Animals; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Signal Transduction	2021
Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice. The Journal of nutrition, 2017, Volume: 147, Issue:6 Topics: Activating Transcription Factor 4; Adipose Tissue; Animals; Body Composition; Diet; eIF-2 Kinase; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Female; Gene Expression; Gene Expression Regulation; Liver; Male; Metabolic Diseases; Methionine; Mice, Inbred C57BL; Obesity; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; RNA, Messenger; Stress, Physiological	2017
Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:6 Topics: Animals; Caloric Restriction; Energy Metabolism; Female; Fibroblast Growth Factors; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Mice; Obesity; Sex Characteristics; Uncoupling Protein 1	2018
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF- The Journal of biological chemistry, 2018, 08-24, Volume: 293, Issue:34 Topics: Animals; Benzofurans; Brain-Derived Neurotrophic Factor; CD36 Antigens; Cell Differentiation; Diet, High-Fat; Insulin Resistance; Intra-Abdominal Fat; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mutation; Obesity; Valine	2018
Dietary methionine restriction regulated energy and protein homeostasis by improving thyroid function in high fat diet mice. Food & function, 2018, Jul-17, Volume: 9, Issue:7 Topics: Animals; Diet, High-Fat; Energy Metabolism; Female; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity; Proteins; Proteostasis; Thyroid Gland; Thyroid Hormone Receptors alpha; Thyrotropin	2018
Dietary Methionine Restriction Upregulates Endogenous H Molecular nutrition & food research, 2019, Volume: 63, Issue:5 Topics: Animals; Body Composition; Body Weight; Cystathionine gamma-Lyase; Diet, High-Fat; Disease Models, Animal; Endoplasmic Reticulum Stress; Hydrogen Sulfide; Liver; Male; Methionine; Mice, Inbred C57BL; MicroRNAs; Obesity; Oxidative Stress; Proteins	2019
Dietary intake of nutrients involved in folate-mediated one-carbon metabolism and risk for endometrial cancer. International journal of epidemiology, 2019, 04-01, Volume: 48, Issue:2 Topics: Aged; Carbon; Case-Control Studies; Diet; Endometrial Neoplasms; Female; Folic Acid; Humans; Methionine; Middle Aged; Obesity; Overweight; Proportional Hazards Models; Prospective Studies; Risk Factors; Vitamin B Complex	2019
The Antisteatotic and Hypolipidemic Effect of Insect Meal in Obese Zucker Rats is Accompanied by Profound Changes in Hepatic Phospholipid and 1-Carbon Metabolism. Molecular nutrition & food research, 2019, Volume: 63, Issue:8 Topics: Animal Feed; Animals; Carbon; Cholesterol; Energy Metabolism; Gene Expression Regulation; Hyperlipidemias; Lipid Metabolism; Liver; Male; Methionine; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats, Zucker; Tenebrio	2019
Dietary methionine restriction ameliorates the impairment of learning and memory function induced by obesity in mice. Food & function, 2019, Mar-20, Volume: 10, Issue:3 Topics: Amino Acids; Animal Feed; Animals; Diet, High-Fat; Learning; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity	2019
Dietary methionine restriction improves glucose metabolism in the skeletal muscle of obese mice. Food & function, 2019, May-22, Volume: 10, Issue:5 Topics: Adipose Tissue, White; Animals; Glucose; Humans; Insulin; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity	2019
American Ginseng and Asian Ginseng Intervention in Diet-Induced Obese Mice: Metabolomics Reveals Distinct Metabolic Profiles. The American journal of Chinese medicine, 2019, Volume: 47, Issue:4 Topics: Animals; Carnitine; Chromatography, Liquid; Cysteine; Diet, High-Fat; Fatty Acids; Glucose; Linoleic Acid; Lipid Metabolism; Male; Mass Spectrometry; Metabolomics; Methionine; Mice, Inbred C57BL; Obesity; Panax; Phytotherapy; Plant Extracts; Taurine	2019
Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children. Gene, 2013, May-15, Volume: 520, Issue:2 Topics: Age of Onset; Alanine Transaminase; Amino Acid Substitution; Case-Control Studies; Child; Female; Genetic Association Studies; Humans; Ideal Body Weight; Isoleucine; Lipase; Liver Diseases; Male; Membrane Proteins; Methionine; Mexico; Obesity; Overweight; Polymorphism, Single Nucleotide	2013
Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. Metabolism: clinical and experimental, 2013, Volume: 62, Issue:11 Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Blood Glucose; Diet; Disease Progression; Fatty Acids; Fatty Liver; Gene Expression Regulation; Homeostasis; Inflammation; Insulin; Leptin; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Methionine; Mice; Mice, Obese; Obesity; Oxidation-Reduction; Severity of Illness Index; Triglycerides	2013
Expression of hepatic fat-specific protein 27 depends on the specific etiology of fatty liver. Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:11 Topics: Animals; Choline Deficiency; Diabetes Mellitus; Diet; Diet, High-Fat; Fatty Liver; Female; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; PPAR gamma; Proteins; RNA, Messenger	2013
Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:4 Topics: Animals; Choline Deficiency; Diabetes Mellitus, Experimental; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity; Organic Anion Transporters; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Tissue Distribution	2014
A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome. The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:4 Topics: Adiponectin; Adult; Age of Onset; Amino Acid Substitution; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Lysine; Male; Metabolic Syndrome; Methionine; Middle Aged; Molecular Weight; Mutation, Missense; Obesity; Protein Multimerization; Young Adult	2014
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochimica et biophysica acta, 2014, Volume: 1842, Issue:7 Topics: Adipogenesis; Adipose Tissue; Animals; Choline; Disease Models, Animal; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Fibroblast Growth Factors; Inflammation; Lipase; Lipid Metabolism; Lipolysis; Liver; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction	2014
Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:2 Topics: Animals; Annexin A1; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity	2014
GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency. Endocrinology, 2014, Volume: 155, Issue:7 Topics: Animals; Blotting, Western; Cell Proliferation; Choline; Diet; Down-Regulation; ErbB Receptors; Fatty Liver; Hepatectomy; Hepatocytes; Human Growth Hormone; Humans; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Triglycerides	2014
Changes in the serum metabolite profile in obese children with weight loss. European journal of nutrition, 2015, Volume: 54, Issue:2 Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Body Mass Index; Child; Child Nutritional Physiological Phenomena; Cohort Studies; Combined Modality Therapy; Diet, Reducing; Down-Regulation; Exercise; Female; Germany; Glutamine; Humans; Life Style; Longitudinal Studies; Lysophosphatidylcholines; Male; Methionine; Obesity; Phospholipid Ethers; Weight Loss	2015
Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis. Archives of biochemistry and biophysics, 2014, Volume: 555-556 Topics: Animals; Choline; Diet; Fatty Liver; Liver; Liver Cirrhosis; Male; Metabolome; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Taurine	2014
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. Aging cell, 2014, Volume: 13, Issue:5 Topics: Animals; Energy Metabolism; Fibroblast Growth Factors; Gene Expression; Glucose; Insulin Resistance; Lipid Metabolism; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity; Phenotype	2014
Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity (Silver Spring, Md.), 2015, Volume: 23, Issue:9 Topics: Adipose Tissue; Adiposity; Animals; Insulin Resistance; Liver; Male; Methionine; Mice; Obesity	2015
Protective effects of maternal methyl donor supplementation on adult offspring of high fat diet-fed dams. The Journal of nutritional biochemistry, 2016, Volume: 34 Topics: Adiposity; Animals; Diet, High-Fat; Dietary Supplements; DNA Methylation; Female; Fetal Development; Gene Expression Regulation, Developmental; Intra-Abdominal Fat; Lactation; Male; Maternal Nutritional Physiological Phenomena; Methionine; Mice, Inbred C57BL; Obesity; Pediatric Obesity; Pregnancy; Pregnancy Complications; Random Allocation; Specific Pathogen-Free Organisms; Weaning; Weight Gain	2016
FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism. Diabetes, 2017, Volume: 66, Issue:4 Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blotting, Western; Diet, High-Fat; Energy Metabolism; Fibroblast Growth Factors; Gene Expression; Glucose Clamp Technique; Insulin Resistance; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Knockout; Obesity; Real-Time Polymerase Chain Reaction; Thermogenesis; Triglycerides	2017
The effect of paternal methyl-group donor intake on offspring DNA methylation and birth weight. Journal of developmental origins of health and disease, 2017, Volume: 8, Issue:3 Topics: Adult; Belgium; Betaine; Birth Weight; Choline; DNA Methylation; Female; Fetal Blood; Folic Acid; Humans; Male; Methionine; Middle Aged; Obesity	2017
Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:5 Topics: Actins; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Choline Deficiency; Diabetes Complications; Disease Models, Animal; Enzyme Inhibitors; Fatty Liver; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Obesity	2009
Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals. Molecular genetics and metabolism, 2009, Volume: 98, Issue:4 Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Fatty Acid-Binding Proteins; Female; Gastrointestinal Hormones; Genetic Predisposition to Disease; Haplotypes; Humans; Male; Methionine; Middle Aged; Molecular Weight; Obesity; Polymorphism, Single Nucleotide; Protein Isoforms; Threonine	2009
Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states. American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:3 Topics: Adipose Tissue; Animals; Body Temperature Regulation; Circadian Rhythm; Diet; Dietary Fats; Energy Metabolism; Food Deprivation; Gene Expression Regulation; Ion Channels; Male; Methionine; Mitochondrial Proteins; Motor Activity; Obesity; Oxygen Consumption; Rats; Rats, Inbred Strains; Uncoupling Protein 1	2010
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention. Physiological genomics, 2011, Apr-27, Volume: 43, Issue:8 Topics: Animals; Blood Glucose; Carbon; Cholesterol; Choline; Dietary Fats; Fatty Liver; Hyperglycemia; Insulin; Insulin Resistance; Liver; Methionine; Mice; Mice, Inbred C57BL; Obesity; Triglycerides	2011
Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:5 Topics: Activating Transcription Factor 6; Animal Feed; Animals; Choline; Choline Deficiency; Cytokines; Diabetes Mellitus, Experimental; Eukaryotic Initiation Factor-2; Fatty Liver; Female; JNK Mitogen-Activated Protein Kinases; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Non-alcoholic Fatty Liver Disease; Obesity; Protein Phosphatase 1; Signal Transduction; Transcription Factor CHOP; Unfolded Protein Response	2011
Association between brain-derived neurotrophic factor Val66Met and obesity in children and adolescents. Progress in neuro-psychopharmacology & biological psychiatry, 2012, Jan-10, Volume: 36, Issue:1 Topics: Adolescent; Alleles; Amino Acid Substitution; Body Mass Index; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Croatia; Eating; Energy Metabolism; Female; Genetic Association Studies; Humans; Male; Methionine; Obesity; Polymorphism, Genetic; Valine	2012
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature, 2012, Feb-01, Volume: 482, Issue:7384 Topics: Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Choline; Colon; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Fatty Liver; Inflammasomes; Inflammation; Interleukin-18; Male; Metagenome; Methionine; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Cell Surface; RNA, Ribosomal, 16S; Toll-Like Receptor 4; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha	2012
Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density. PloS one, 2012, Volume: 7, Issue:12 Topics: Adiponectin; Analysis of Variance; Animals; Bone Density; Collagen Type I; Diet, High-Fat; Disease Resistance; DNA Primers; Fibroblast Growth Factors; Gene Expression Profiling; Gene Expression Regulation; Glucose Tolerance Test; Histological Techniques; Insulin Resistance; Insulin-Like Growth Factor I; Leptin; Methionine; Mice; Mice, Inbred C57BL; Obesity; Real-Time Polymerase Chain Reaction; Rotarod Performance Test	2012
An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis. International journal of experimental pathology, 2013, Volume: 94, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Choline Deficiency; Diet, Fat-Restricted; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Humans; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred A; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Specific Pathogen-Free Organisms; Time Factors	2013
Impaired hepatic mitochondrial oxidation using the 13C-methionine breath test in patients with macrovesicular steatosis and patients with cirrhosis. Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1 Topics: Adult; Aged; Aminopyrine; Biopsy; Breath Tests; Case-Control Studies; Female; Fibrosis; Hepatocytes; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases; Male; Methionine; Middle Aged; Mitochondria, Liver; Obesity; Oxygen; Time Factors	2003
Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:5 Topics: Animals; Cell Line; Choline Deficiency; Deficiency Diseases; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Osteopontin; Receptors, Cell Surface; Receptors, Leptin; Sialoglycoproteins	2004
Metabolic profiling of livers and blood from obese Zucker rats. Journal of hepatology, 2006, Volume: 44, Issue:5 Topics: Animals; Betaine; Energy Metabolism; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Fatty Liver; Glutathione; Glycolysis; Lipid Peroxidation; Liver; Magnetic Resonance Spectroscopy; Male; Methionine; Mitochondria; Obesity; Rats; Rats, Zucker; Reperfusion Injury; Triglycerides	2006
Preproghrelin Leu72Met polymorphism in obese Korean children. Journal of pediatric endocrinology & metabolism : JPEM, 2005, Volume: 18, Issue:11 Topics: Body Mass Index; Child; Cholesterol; Female; Genetic Carrier Screening; Ghrelin; Humans; Korea; Leucine; Male; Methionine; Motilin; Obesity; Polymorphism, Genetic; Triglycerides	2005
Overexpression of angiopoietin-like protein 4 alters mitochondria activities and modulates methionine metabolic cycle in the liver tissues of db/db diabetic mice. Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:4 Topics: Adenoviridae; Angiopoietin-Like Protein 4; Angiopoietins; Animals; Blood Proteins; Diabetes Mellitus; Down-Regulation; Electron Transport; Electrophoresis, Gel, Two-Dimensional; Liver; Methionine; Mice; Mice, Mutant Strains; Mitochondria, Liver; Mitochondrial Proteins; Obesity; Proteomics	2007
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterology, 2007, Volume: 132, Issue:1 Topics: Animal Feed; Animals; Choline; Collagen Type I; Collagen Type I, alpha 1 Chain; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Methionine; Obesity; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; Rats; Rats, Inbred OLETF; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones; Transforming Growth Factor beta; Up-Regulation	2007
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:6 Topics: Adiponectin; Animal Feed; Animals; Blood Glucose; Choline; Cytochrome P-450 CYP2E1; Diacylglycerol O-Acyltransferase; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Insulin; Lipid Peroxidation; Liver Cirrhosis; Male; Methionine; Mice; Mice, Mutant Strains; Obesity; Oligoribonucleotides, Antisense; Oxidative Stress; Triglycerides; Tumor Necrosis Factor-alpha	2007
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Digestive diseases and sciences, 2008, Volume: 53, Issue:10 Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated; Glutathione; Hepatitis; Homeostasis; Lipid Metabolism; Liver; Methionine; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; S-Adenosylmethionine	2008
Mutation screening and identification of a sequence variation in the human ob gene coding region. Biochemical and biophysical research communications, 1996, Mar-27, Volume: 220, Issue:3 Topics: Adipose Tissue; Alternative Splicing; Base Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Female; Genetic Variation; Glutamine; Humans; Introns; Leptin; Male; Methionine; Molecular Sequence Data; Nucleic Acid Conformation; Obesity; Point Mutation; Polymerase Chain Reaction; Proteins; Reference Values; Restriction Mapping; RNA, Messenger; Sex Characteristics	1996
The 677C-->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease. Atherosclerosis, 1997, Jul-11, Volume: 132, Issue:1 Topics: Adult; Aged; Alcohol Drinking; Case-Control Studies; Comorbidity; Coronary Artery Disease; Disease Susceptibility; Erythrocytes; Fasting; Female; Folic Acid; Genes; Genotype; Homocysteine; Humans; Hyperlipidemias; Hypertension; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Smoking	1997
In vitro methionine oxidation of recombinant human leptin. Pharmaceutical research, 1998, Volume: 15, Issue:4 Topics: Adipose Tissue; Detergents; Endopeptidases; Humans; Hydrogen Peroxide; Leptin; Metalloendopeptidases; Methionine; Obesity; Oxidation-Reduction; Peptide Mapping; Peroxides; Proteins; Reactive Oxygen Species; Recombinant Proteins; tert-Butylhydroperoxide	1998
Identification and functional analysis of novel human melanocortin-4 receptor variants. Diabetes, 1999, Volume: 48, Issue:3 Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Body Mass Index; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Isoleucine; Male; Methionine; Mice; Middle Aged; Obesity; Pedigree; Polymorphism, Single-Stranded Conformational; Receptor, Melanocortin, Type 4; Receptors, Peptide; Recombinant Proteins; Threonine; Valine	1999
Determinants of homocysteine during weight reduction in obese children and adolescents. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:10 Topics: Adolescent; Age Factors; Body Composition; Body Mass Index; C-Peptide; Child; Folic Acid; Homocysteine; Humans; Methionine; Obesity; Regression Analysis; Time Factors; Weight Loss	2001
Utilization of D-methionine during total parenteral nutrition in postsurgical patients. The American journal of clinical nutrition, 1979, Volume: 32, Issue:6 Topics: Adult; Amino Acids; Erythrocytes; Glucose; Humans; Methionine; Obesity; Parenteral Nutrition; Parenteral Nutrition, Total; Postoperative Care; Stereoisomerism; Stomach	1979
[Growth disorders. Classification, diagnosis, therapy. 3. Excessive growth: constitutional tallness, endocrine tallness, chromosome abnormalities, tallness with unusual proportions, tallness in metabolic diseases]. Fortschritte der Medizin, 1979, Nov-22, Volume: 97, Issue:44 Topics: Adult; Child; Chromosome Aberrations; Chromosome Disorders; Endocrine System Diseases; Growth Disorders; Homocystinuria; Humans; Marfan Syndrome; Methionine; Obesity; Puberty, Precocious	1979
A mutation in the tyrosine kinase domain of the insulin receptor associated with insulin resistance in an obese woman. The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:4 Topics: Adult; Exons; Female; Fibroblasts; Humans; Insulin Resistance; Isoleucine; Methionine; Mutation; Obesity; Protein-Tyrosine Kinases; Receptor, Insulin	1991
Decreased levels of hepatic epidermal growth factor receptors in obese hyperglycemic rodents. The Journal of biological chemistry, 1987, Sep-05, Volume: 262, Issue:25 Topics: Animals; ErbB Receptors; Hyperglycemia; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Molecular Weight; Obesity; RNA, Messenger; Transcription, Genetic	1987
Transport of -aminoisobutyric acid in mammalian pancretic -cells. Diabetologia, 1971, Volume: 7, Issue:4 Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Butyrates; Cyclic AMP; Diazoxide; Galactose; Glucose; Hyperglycemia; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Methionine; Mice; Monosaccharides; Obesity; Sodium	1971
Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects. The Journal of clinical investigation, 1974, Volume: 54, Issue:4 Topics: Amino Acids; Female; Humans; Infusions, Parenteral; Isoleucine; Keto Acids; Leucine; Methionine; Nitrogen; Obesity; Phenylalanine; Starvation; Urea; Valine	1974
Human utilization of urea nitrogen in low calorie diets. The Journal of nutrition, 1971, Volume: 101, Issue:8 Topics: Adult; Amino Acids; Animals; Basal Metabolism; Body Weight; Diet, Reducing; Dietary Carbohydrates; Female; Humans; Lysine; Methionine; Milk; Nitrogen; Nutritional Requirements; Obesity; Time Factors; Urea	1971
Influence of body composition, methionine deficiency or toxicity and ambient temperature on feed intake in the chick. The Journal of nutrition, 1968, Volume: 96, Issue:3 Topics: Animal Nutritional Physiological Phenomena; Animals; Appetite; Body Composition; Body Weight; Chickens; Deficiency Diseases; Diet; Male; Methionine; Obesity; Proteins; Temperature	1968
Functional and allometric descriptions of the liver and small intestine in genetically obese mice. The Journal of nutrition, 1966, Volume: 90, Issue:4 Topics: Animals; Glucose; Histocytochemistry; Hyperglycemia; Intestine, Small; Liver; Methionine; Mice; Obesity; Organ Size	1966