methionine has been researched along with Neoplasms in 236 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (27.54) | 18.7374 |
| 1990's | 22 (9.32) | 18.2507 |
| 2000's | 35 (14.83) | 29.6817 |
| 2010's | 71 (30.08) | 24.3611 |
| 2020's | 43 (18.22) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Chen, GQ; Chen, R; Cheng, J; Fang, J; Guo, Y; He, J; Huang, C; Huang, J; Li, L; Liu, X; Lu, R; Qiang, Z; Wang, Y; Yang, Q; Yu, J; Zhang, H; Zhao, X | 1 |
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| El-Mesery, M; Frackmann, K; Koderer, C; Kübler, AC; Linz, C; Ries, E; Schmitz, W; Seher, A; Völter, MF; Wünsch, AC | 1 |
| Ghergurovich, JM; Rabinowitz, JD; Ryseck, RP; Wang, JZ; Wang, L; Xu, X; Yang, L | 1 |
| Han, Q; Hoffman, RM; Simon, M; Thomas, D; Yamamoto, J | 1 |
| Balint, J; El-Mesery, M; Hartmann, S; Koderer, C; Kübler, AC; Linz, C; Schmitz, W; Seher, A; Volland, JM; Wünsch, AC | 1 |
| Korimerla, N; Wahl, DR | 1 |
| Buettner, R; Guo, J; Rosen, ST; Yang, Y | 1 |
| Gui, G; Li, C; Qin, A; Zha, X; Zhang, L; Zhou, C | 1 |
| Chen, YX; Ju, HQ; Li, T; Liao, K; Lin, J; Mo, HY; Piao, HL; Tan, YT; Wang, W; Xu, RH; Yang, W; Zheng, XJ | 1 |
| Atkinson, SJ; Evans, L; Scott, JS | 1 |
| Hofer, SJ; Kepp, O; Kroemer, G | 1 |
| Hlozkova, K; Safrhansova, L; Starkova, J | 1 |
| Chéry, C; Guéant, JL; Namour, F; Oussalah, A; Siblini, Y | 1 |
| Bao, W; Cheng, TD; Fowke, JH; Johnson, KC; Liang, X; Liu, B; Mozhui, K; Saquib, N; Sen, S; Shadyab, AH; Snetselaar, LG; Sun, Y; Wallace, RB | 1 |
| Alt, K; Candace Ho, YT; Casey, JL; Cryle, MJ; Hagemeyer, CE; Hashad, RA; Jap, E; Lupton, DW; Robert, R; Sleeman, M; Thalmann, C; Wright, A | 1 |
| Berglund, A; Brown, J; El-Kenawi, A; Estrella, V; Gatenby, R; Johnson, J; Liu, M; Putney, RM; Yoder, SJ; Zhang, Y | 1 |
| Guo, H; Honda, Y; Kanamori, K; Matsui, M; Nishiyama, N; Nomoto, T; Takemoto, H; Voon, YM; Xu, W; Yamada, N | 1 |
| Chong, G; Dong, H; Gu, J; He, R; Li, Y; Liu, B; Liu, Y; Yang, Y; Yin, W; Zang, J; Zhang, T; Zhao, Y; Zheng, X | 1 |
| Bessonov, N; Eymard, N; Gueyffier, F; Kurbatova, P; Nony, P; Volpert, V | 1 |
| Liu, M; Liu, Z; Qu, X; Ren, J; Wang, W; Zhang, L; Zhang, Y; Zhu, J | 1 |
| Ahn, JH; Chang, JH; Gu, Y; Han, Y; Jeong, MS; Kang, B; Kil, YS; Kim, JO; Ko, HJ; Mishra, S; Nam, JW; Ouh, YT; Pandit, M; Pokhrel, RH | 1 |
| Lai, Y; Li, F; Liang, Z; Lin, Y; Lu, M; Mo, X; Mu, Y; Qu, J; Shao, Z; Shen, H; Wang, X; Zhao, AZ; Zhao, Z; Zhou, S | 1 |
| Hotta, M; Inoshita, N; Ishida, A; Kaneko, K; Minamimoto, R; Takano, K; Yamada, S | 1 |
| Cui, T; Huang, Y; Qin, G; Qu, X; Ren, J; Zhao, C | 1 |
| Joulia, E; Metallo, CM | 1 |
| Anantharaman, K; Andrea Azcarate-Peril, M; Arbeev, KG; Garcia-Peterson, LM; Hsiao, YC; Ji, M; Li, JL; Li, X; Liu, J; Lu, K; Martin, C; Popov, V; Randall, TA; Shats, I; Ukraintseva, S; Wan, Y; Wu, X; Xu, Q; Xu, X; Yashin, AI | 1 |
| Aprile, FA; Ge, Y; Long, NJ; Ma, MT; Pham, TT; Yue, TTC | 1 |
| Lu, W; Luo, Y | 1 |
| DeNicola, GM; Ward, NP | 1 |
| Dai, Z; Gao, X; Locasale, JW; Sanderson, SM | 1 |
| Berisa, M; Cross, JR; Qin, W; Schwörer, S; Thompson, CB; Zhu, J | 1 |
| Ardestani, MS; Ebrahimi, SES; Farzaneh, J; Hadadian, S; Hamedani, MP; Karimpourfard, N; Mojarrad, P; Omoomi, FD; Seyedhamzeh, M; Zamani, S | 1 |
| Birsoy, K; Weber, R | 1 |
| Hobson, K; Ji, X; Wanders, D | 1 |
| Kaiser, P | 1 |
| Guéant, JL; Hsu, SB; Namour, F; Oussalah, A; Siblini, Y; Zgheib, R | 1 |
| Li, AM; Ye, J | 1 |
| Chu, CC; Xu, Q | 1 |
| Athineos, D; Bauer, C; Blyth, K; Maddocks, ODK; Newman, AC; Uribe, AH; Zhang, T | 1 |
| Gubser, PM; Kallies, A | 1 |
| Bian, Y; Chinnaiyan, AM; Cieslik, M; Crespo, J; Czerwonka, A; Grove, S; Kremer, DM; Kryczek, I; Li, J; Li, S; Li, W; Liao, P; Liu, JR; Lyssiotis, CA; McLean, K; Nwosu, ZC; Okła, K; Pawłowska, A; Sajjakulnukit, P; Szeliga, W; Vatan, L; Wallner, G; Wei, S; Wertel, I; Xia, H; Yu, J; Zgodziński, W; Zhang, L; Zou, W | 1 |
| Dotsenko, O; Shtofel, D | 1 |
| Li, MO; Shyu, A; Xu, K | 1 |
| Gilfix, BM; Rosenblatt, DS; Sorin, M; Watkins, D | 1 |
| Huang, J; Liu, G; Liu, J; Wu, J; Xin, P | 1 |
| Albayati, S; Uba, AI; Yelekçi, K | 1 |
| Hoffman, RM | 9 |
| Aguera, K; Berlier, W; Bourgeaux, V; Gay, F; Godfrin, Y; Honnorat, J; Horand, F; Maucort-Boulch, D; Sénéchal, K; Tainturier, A | 1 |
| Padovani, D | 1 |
| Bin, P; Hu, CA; Li, X; Liu, G; Martínez, Y; Más, D; Ren, W; Valdivié, M; Yan, W; Yin, Y | 1 |
| Kim, G; Levine, RL; Lim, JM | 1 |
| Heikkinen, S; Horkka, K; Kavakka, J; Moilanen, JO; Soikkeli, M; Timonen, M | 1 |
| Bertino, JR; Chaturvedi, S; Hoffman, RM | 1 |
| Dai, Z; Gao, X; Locasale, JW; Mentch, SJ; Nichenametla, SN | 1 |
| Chen, H; Er, M; Gui, L; He, Q; Kassaye, H; Ma, Y; Wan, H; Wang, F; Wei, C; Xu, Y; Yuan, Z; Zheng, J | 1 |
| Ewing, LE; Griffin, RJ; Koturbash, I; Kutanzi, KR; Miousse, IR | 1 |
| Li, Q; Pan, Y; Qin, X; Xu, C; Yu, H; Yue, P; Zhang, W; Zhou, Q; Zhu, M | 1 |
| Hagiwara, N; Ito, K; Kume, S; Matsuura, K; Shimizu, T; Shiraki, N | 1 |
| Gu, W; Herring, J; Ou, Y; Sowers, ML; Tang, H; Zhang, K; Zhang, W | 1 |
| Moskovitz, J; Oien, DB | 1 |
| Gao, Y; Li, W; Li, Z; Ma, Y; Qin, X; Wang, D; Yin, F; Yu, Z; Zhou, Z | 1 |
| Bertino, JR; Chaturvedi, S | 1 |
| Coalson, DW; Douglas Wallace, C; Erbe, RW; Hoffman, RM; Stern, PH | 1 |
| Erbe, RW; Hoffman, RM | 1 |
| Borrego, SL; Kaiser, P; Lin, DW | 1 |
| Guo, W; Hoffman, RM; Hoshiya, Y | 1 |
| Hoffman, RM; Stern, PH | 2 |
| Frenkel, EP; Hoffman, RM; Kokkinakis, DM | 1 |
| Han, Q; Hoffman, RM; Li, S; Tan, Y; Zavala, J | 1 |
| Labuschagne, CF; Maddocks, ODK; Newman, AC; Vousden, KH | 1 |
| Han, Q; Hoffman, RM; Igarashi, K; Kawaguchi, K; Li, S; Murakami, T; Tan, Y; Unno, M | 1 |
| Dai, Z; Locasale, JW; Mikhael, PG; Ramesh, V; Sanderson, SM | 1 |
| Cravatt, BF; Ulanovskaya, OA; Zuhl, AM | 1 |
| Fukuda, H; Kubota, K; Matsuzawa, T | 1 |
| Butch, ER; Davis, JC; Harris, SM; Kocak, M; Shulkin, BL; Snyder, SE; Vavere, AL | 1 |
| Ashida, H; Chun, KH; Hah, SS; Hong, SH; Jung, YK; Kang, W; Kim, HC; Kim, NY; Kim, TY; Le, le TM; Lee, HM; Lim, B; Lim, YC; Yang, JK; Yokota, A | 1 |
| Antunovic, L; Chiti, A; Rodari, M; Rossi, P | 1 |
| Adhikari, A; Chuttani, K; Datta, A; Kadiyala, KG; Kumar, BS; Mishra, AK; Tanwar, J; Thirumal, M | 1 |
| Kanwar, SS; Sharma, B; Singh, S | 1 |
| Bhonsle, HK; Hazari, PP; Jaswal, A; Khurana, H; Meena, VK; Mishra, AK; Mishra, SK; Prakash, S; Singh, L | 1 |
| Ahuja, LG; Hu, J; Kannan, N; Kornev, AP; Meharena, HS; Shaw, AS; Taylor, SS | 1 |
| Cui, G; Di, LJ; Wang, L; Wang, Y; Zhou, H | 1 |
| Archakov, AI; Chernobrovkin, AL; Gorshkov, MV; Ilina, IY; Ivanov, MV; Karpov, DS; Karpova, MA; Kopylov, AT; Kuznetsova, KG; Moshkovskii, SA; Moysa, AA; Pyatnitskiy, MA; Veselovsky, AV; Zgoda, VG | 1 |
| Adams, PD; Labuschagne, CF; Maddocks, OD; Vousden, KH | 1 |
| Metallo, CM; Parker, SJ | 1 |
| Billy, E; Capka, V; Cho, YS; Ciccone, D; Crawford, K; deBeaumont, R; deWeck, A; Gao, H; Gu, J; Ho, S; Hoffman, GR; Hofmann, F; Hurov, K; Keen, N; Kipp, DR; Lai, A; Lees, E; Lin, F; Lin, Y; Liu, Y; Mavrakis, KJ; McAllister, G; McDonald, ER; McNamara, JT; Mickanin, C; Pagliarini, R; Porter, JA; Ruddy, DA; Schlabach, MR; Schmelzle, T; Sellers, WR; Sprague, ER; Stegmeier, F; Stump, M; Tallarico, J; Venkatesan, K; Vitari, AC; Yan-Neale, Y; Yang, G; Yin, H; Yu, J; Yue, Y; Zhao, S; Zheng, B | 1 |
| Ables, GP; Hens, JR; Nichenametla, SN | 1 |
| Shipman, L | 1 |
| Coover, RA; Doughty, TW; Ellis, KC; Grossman, SR; Hilbert, BJ; Kellogg, GE; Korwar, S; Love, IM; Morris, BL; Parikh, HI; Royer, WE | 1 |
| Bian, K; Keidar, M; Murad, F; Nourmohammadi, N; Sherman, JH; Yan, D | 1 |
| Suematsu, M; Yamamoto, T | 1 |
| Doronin, AI; Kotomtsev, VV; Pavlov, VA; Sabadash, EV | 1 |
| Du, W; Ji, M; Sun, C; Wang, B; Zhang, H | 1 |
| Ables, GP; Johnson, JE | 1 |
| Jain, M; Nilsson, R; Roci, I; Watrous, J | 1 |
| Cabrera, D; Di Luca, A; Falcon-Perez, JM; Henry, M; Lima, RT; Lopes-Rodrigues, V; Meleady, P; Mleczko, J; O'Connor, R; Pesic, M; van Liempd, S; Vasconcelos, MH | 1 |
| Belka, C; Bullinger, D; Fux, R; Gleiter, CH; Kammerer, B; Laufer, S; Nicholson, G; Plontke, S | 1 |
| Allegri, V; Astorino, M; Biasco, G; Boschi, S; Brandi, G; Castellucci, P; Di Battista, M; Fanti, S; Lodi, F; Lopci, E; Maleddu, A; Nanni, C; Nannini, M; Pantaleo, MA | 1 |
| Alonso, S; Huang, S; Lu, SC; Perucho, M; Takai, D; Yamamoto, F; Zhou, W | 1 |
| Bera, S; Ray, M; Ray, S; Wallimann, T | 1 |
| Anastasio, N; Lavoie, J; Lerner-Ellis, JP; Loewy, AD; Niles, KM; Pastinen, T; Rosenblatt, DS; Trasler, JM; Watkins, D | 1 |
| Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y | 1 |
| Chuttani, K; Goel, V; Hazari, PP; Kumar, N; Mishra, AK; Sharma, R; Shukla, G | 1 |
| Fanti, S; Fantini, L; Nanni, C; Nicolini, S | 1 |
| Brumaghim, JL; Ramoutar, RR | 1 |
| Fukui, J; Kadariya, Y; Kruger, WD; Myers, CB; Peterson, JR; Tang, B | 1 |
| Hatano, T; Kohanawa, M; Kuge, Y; Magota, K; Nishijima, K; Tamaki, N; Yi, M; Zhao, S; Zhao, Y | 1 |
| Agrawal, V; Alpini, SE; Frankel, AE; Frenkel, EP; Stone, EM | 1 |
| Marcus, DM; Shim, H; Shu, HK; Zhu, A | 1 |
| Cavuoto, P; Fenech, MF | 1 |
| Hochreuther, S; van Eldik, R | 1 |
| Du, C; Gu, Y; Jie, C; Mahounga, DM; Shan, L; Wan, S | 1 |
| Chi, LM; Chien, KY; Hsieh, YJ; Hsu, RM; Lin, SY; Lyu, PC; Sabu, S; Yu, JS | 1 |
| Aghasadeghi, MR; Alavidjeh, MS; Amanlou, M; Ardestani, MS; Daha, FJ; Ebrahimi, SE; Ghorbani, M; Khosroshahi, AG; Mousavi, L; Pouriayevali, MH; Sabzevari, O; Sadat, SM | 1 |
| Huang, S | 1 |
| Epner, DE; Houghton, JL; Morrow, S; Wilcox, M | 1 |
| GOLDKAMP, AH; MELCHIOR, JB | 1 |
| STEPANOVA, MM | 1 |
| SMOILOVSKAIA, EIa | 1 |
| ALLISON, JB; HETZEL, CA; HILF, R; WANNEMACHER, RW | 1 |
| GHADIALLY, FN; WISEMAN, G | 1 |
| GREENBERG, DM; OLSON, ME; RABINOVITZ, M | 1 |
| ALLISON, JB; McCOY, JR; RUSSELL, T; WANNEMACHER, RW | 1 |
| DUNN, MS; MURPHY, EA | 1 |
| MEHL, JW; STEIN, AM | 1 |
| DI MICELI, A; GIUDICE, G; MUTOLO, V | 1 |
| SPASSKAIA, IG | 1 |
| JOHNSON, JM; RABINOVITZ, M | 1 |
| WANNEMACHER, RW | 1 |
| JOHNSTONE, RM; SCHOLEFIELD, PG | 1 |
| LOH HOEHN-SARIC, E; NYHAN, WL | 1 |
| CESTARI, A; CONCILIO, C; DESSI, P; RIZZOLI, C | 1 |
| GAISFORD, WD; KIRSH, M; KOWALCZYK, RS; POWERS, W; TURCOTTE, JG; ZUIDEMA, GD | 1 |
| CHO, YS; MORRIS, HP; PITOT, HC | 1 |
| FARBER, E | 1 |
| KINOSITA, R; MIYAJI, H | 1 |
| RUTENBURG, AM; SMITH, EE | 1 |
| BEIERWALTES, WH; DIGIULINO, W | 1 |
| PRZYMANOWSKI, Z | 1 |
| DUNN, WL | 1 |
| Cellarier, E; Chollet, P; Demiden, A; Durando, X; Farges, MC; Madelmont, JC; Maurizis, JC; Vasson, MP | 1 |
| Tapiero, H; Tew, KD; Townsend, DM | 1 |
| BLOCH, HS; HITCHCOCK, CR; KREMEN, AJ | 1 |
| HOLMES, BE; MEE, LK | 1 |
| Golab, J; Jakobisiak, M; Kopec, M; Legat, M; Makowski, M; Strusinska, K | 1 |
| Avila, MA; Corrales, FJ; García-Trevijano, ER; Lu, SC; Mato, JM | 1 |
| Davis, CD; Uthus, EO | 1 |
| Basilico, C; Cavassa, S; Comoglio, PM; Mazzone, M; Michieli, P; Naldini, L; Pennacchietti, S; Risio, M | 1 |
| Banerjee, R; Bauman, Z; Braun, A; Madzelan, P; Olteanu, H; Zhang, W | 1 |
| Baar, C; Dale, O; Kaasa, S; Klepstad, P; Krokan, HE; Kvam, TM; Rakvåg, TT; Skorpen, F | 1 |
| Double, JA; Nicolaou, A; Pavillard, V; Phillips, RM | 1 |
| Kokkinakis, DM | 1 |
| Dent, CE; Rose, GA | 1 |
| Al-Nahhas, A; Fanti, S; Nanni, C; Rubello, D | 1 |
| Adnane, J; Bizouarn, F; Blaskovich, MA; Chellappan, S; Delarue, FL; Hamilton, AD; Hawker, J; Joshi, B; Ohkanda, J; Sebti, SM; Wang, DA; Zhu, K | 1 |
| Bonatto, D; Rosado, JO; Salvador, M | 1 |
| Hagen, K; Pettersen, E; Skorpen, F; Stovner, LJ; Zwart, JA | 1 |
| Abrial, C; Cellarier, E; Chollet, P; Dib, M; Durando, X; Gimbergues, P; Tacca, O; Thivat, E | 1 |
| Toohey, JI | 1 |
| Lawrance, AK; Rozen, R; Stankova, J | 1 |
| de Camargo, JL; Nauss, KM; Newbene, PM | 1 |
| Beaney, RP | 1 |
| Chaney, JE; Digenis, GA; Goto, R; Takeda, A; Tamemasa, O | 1 |
| Tisdale, MJ | 3 |
| Hoffman, RM; Mecham, JO; Rowitch, D; Stern, PH; Wallace, CD | 1 |
| Hoffman, RM; Stern, PH; Wallace, CD | 1 |
| Marshall, MC; Weintraub, BD; Williams, D | 1 |
| Hida, K; Kano, Y; Kubota, T; Sakamoto, S; Sakuraya, K; Suda, K; Takaku, F | 1 |
| Christman, JK | 1 |
| Rogers, AE | 1 |
| Leskinen-Kallio, S | 1 |
| Chen, ZP; Leavitt, J; Park, T | 1 |
| Engel, RR; Receveur, O | 1 |
| Gatton-Umphress, TL; Seidler, NW; Weber, KA | 1 |
| Groce, A; Guo, HY; Herrera, H; Hoffman, RM | 1 |
| Kubota, K | 2 |
| Henning, SM; Swendseid, ME | 1 |
| Kusić, Z; Lacić, M; Maisey, MN | 1 |
| Balkay, L; Emri, M; Esik, O; Galuska, L; Kovács, Z; Márián, T; Molnár, T; Sarkadi, E; Szakáll, S; Tóth, E; Trón, L | 1 |
| An, Z; Han, Q; Hoffman, RM; Miljkovic, DA; Sun, X; Tan, X; Tan, Y; Xu, M; Yang, M | 1 |
| Watkins, D | 1 |
| Yoshido, S | 1 |
| Avril, N; Schwaiger, M; Weber, WA | 1 |
| Kubota, T | 1 |
| Bødrogi, I; Dóczi, T; Esik, O; Fekete, S; Galuska, L; Kálvin, B; Kásler, M; Kubinyi, K; Lengyel, Z; Losonczy, H; Nyáry, I; Rácz, K; Rosta, A; Szakáll, S; Szentirmay, Z; Sziklai, I; Trón, L; Vitéz, A | 1 |
| Dutrillaux, B; Gonçalves, RA; Miccoli, L; Poirson-Bichat, F; Poupon, MF | 1 |
| Refsum, H; Schneede, J; Ueland, PM | 1 |
| Brown, JM | 1 |
| Bernhard, EJ; Cohen-Jonathan, E; Evans, SM; Koch, CJ; McKenna, WG; Muschel, RJ; Wu, J | 1 |
| de Vries, EG; Jager, PL; Langen, KJ; Piers, DA; Pruim, J; Vaalburg, W | 1 |
| Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
| Epner, DE | 1 |
| Mathé, G | 1 |
| Deng, L; Hiou-Tim, F; James, SJ; Melnyk, S; Pogribny, IP; Rozen, R; Sibani, S; Trasler, J; Wang, W | 1 |
| Cabrera Villegas, A; Gámez Cenzano, C; García Velloso, MJ; Sopena Monforte, R | 1 |
| DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS | 1 |
| Nakajima, T; Tanaka, T | 1 |
| Levi, RN; Waxman, S | 1 |
| Fateeva, MN; Zherbin, EA | 1 |
| Holland, JF; Ohnuma, T | 1 |
| Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y | 1 |
| Wilson, CB | 1 |
| Boyd, AW; Busmanis, I; Loudovaris, M; Rockman, S; Salvaris, E; Simpson, RJ; Ward, LD; Welch, K; Wicks, IP; Wilks, A | 1 |
| Matsumoto, H; Mori, S | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Dana, BW; Ferro, AJ; Fitchen, JH; Lawrence, HJ; Riscoe, MK | 1 |
| Frost, P; Judde, JG | 1 |
| Fukuda, H; Matsuzawa, T; Tateno, Y | 1 |
| Bading, J; Benua, RS; Gelbard, AS; Laughlin, JS; Magill, GB; Reiman, RE; Sordillo, PP | 1 |
| Eto, I; Krumdieck, CL | 1 |
| Antecol, MH; Darveau, A; Mukherjee, BB; Sonenberg, N | 1 |
| van der Westhuyzen, J | 1 |
| Gottschalk, A; Hoffer, PB | 1 |
| Evans, VJ; Gantt, R | 1 |
| Craddock, VM | 1 |
| Bohuon, C; Caillard, L | 1 |
| Ackerman, NB | 1 |
| Björnesjö, KB | 1 |
| Jovanovic, D | 1 |
| Neher, R; Riniker, B; Rittel, W; Zuber, H | 1 |
| Grace, JT; Jones, R; Mittelman, A; Tritsch, GL | 1 |
| Altenbrunn, HJ; Andrysek, O; Andryskova, J; Berndt, H | 1 |
| Menkès, G | 1 |
71 review(s) available for methionine and Neoplasms
| Article | Year |
|---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
Methionine Restriction: Ready for Prime Time in the Cancer Clinic?
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carbon-Sulfur Lyases; Diet, Protein-Restricted; Humans; Methionine; Neoplasms | 2022 |
Interactions between Radiation and One-Carbon Metabolism.
Topics: Carbon; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Neoplasms | 2022 |
Targeting the methionine-methionine adenosyl transferase 2A- S -adenosyl methionine axis for cancer therapy.
Topics: Animals; Carcinogenesis; Humans; Mammals; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine | 2022 |
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors.
Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine | 2022 |
A patent review of MAT2a inhibitors (2018-2021).
Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Patents as Topic; Protein-Arginine N-Methyltransferases; S-Adenosylmethionine | 2022 |
Targeting amino acid metabolism in cancer.
Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms | 2022 |
Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players.
Topics: Methionine; Neoplasms; Neoplastic Stem Cells; PPAR alpha; Racemethionine; S-Adenosylmethionine; Sirtuin 1 | 2022 |
Sulfur metabolism and its contribution to malignancy.
Topics: Animals; Carcinogenesis; Chelating Agents; Cysteine; Humans; Metallothionein; Methionine; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Sulfur | 2019 |
Methionine metabolism in health and cancer: a nexus of diet and precision medicine.
Topics: Animals; Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Deletion; Histones; Humans; Methionine; Neoplasms; Nutritional Sciences; Oxidation-Reduction; Polyamines; Precision Medicine; RNA | 2019 |
Methionine Restriction and Cancer Biology.
Topics: Animals; Humans; Methionine; Neoplasms | 2020 |
Methionine Dependence of Cancer.
Topics: Animals; Humans; Methionine; Neoplasms | 2020 |
Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Methionine; Neoplasms; Neoplastic Stem Cells; Vitamin B 12 | 2020 |
Reprogramming of serine, glycine and one-carbon metabolism in cancer.
Topics: Animals; Carbon; Cellular Reprogramming; Glycine; Humans; Metabolic Networks and Pathways; Methionine; Mitochondria; Neoplasms; Protein Processing, Post-Translational; Serine; Transcription Factors | 2020 |
Methionine dependence in tumor cells: The potential role of cobalamin and MMACHC.
Topics: DNA Methylation; Genomics; Humans; Methionine; Neoplasms; Oxidoreductases; Sequence Analysis, RNA; Vitamin B 12 | 2021 |
Biomedical applications of methionine-based systems.
Topics: Cell Proliferation; COVID-19; COVID-19 Drug Treatment; Docetaxel; Humans; Liver Diseases; Methionine; Nanoparticles; Neoplasms; S-Adenosylmethionine; SARS-CoV-2 | 2021 |
The wayward methyl group and the cascade to cancer.
Topics: Aneuploidy; Animals; Cell Cycle Checkpoints; DNA Methylation; Genomic Instability; Humans; Methionine; Neoplasms | 2017 |
The role of methionine on metabolism, oxidative stress, and diseases.
Topics: Animals; Cardiovascular Diseases; Humans; Immunity, Innate; Kidney Diseases; Lipid Metabolism; Liver Diseases; Methionine; Neoplasms; Nervous System Diseases; Oxidative Stress | 2017 |
Methionine in Proteins: It's Not Just for Protein Initiation Anymore.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Humans; Methionine; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Protein Processing, Post-Translational | 2019 |
Exploiting methionine restriction for cancer treatment.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Humans; Methionine; Neoplasms; Purine-Nucleoside Phosphorylase; Tetrahydrofolates; Treatment Outcome; Tumor Cells, Cultured | 2018 |
DNA Methylation in Radiation-Induced Carcinogenesis: Experimental Evidence and Clinical Perspectives.
Topics: Animals; Cell Transformation, Neoplastic; DNA Damage; DNA Methylation; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methionine; Molecular Targeted Therapy; Mutation; Neoplasms; Radiation, Ionizing; Repetitive Sequences, Nucleic Acid | 2018 |
Genetic regulation of longevity and age-associated diseases through the methionine sulfoxide reductase system.
Topics: Aging; Animals; Gene Expression Regulation; Humans; Longevity; Methionine; Methionine Sulfoxide Reductases; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress | 2019 |
Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review.
Topics: Animals; Carbon-Sulfur Lyases; Humans; Methionine; Mice, Nude; Neoplasms; Recombinant Proteins; Treatment Outcome; Xenograft Model Antitumor Assays | 2019 |
Pioneering and fundamental achievements on the development of positron emission tomography (PET) in oncology.
Topics: Carbon Radioisotopes; Diagnosis, Differential; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals | 2013 |
Standardization and quantification in PET/CT imaging: tracers beyond FDG.
Topics: Carbon Radioisotopes; Choline; Humans; Medical Oncology; Methionine; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Reference Standards; Tomography, X-Ray Computed | 2014 |
L-methionase: a therapeutic enzyme to treat malignancies.
Topics: Animals; Carbon-Sulfur Lyases; Humans; Methionine; Models, Biological; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms | 2014 |
Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.
Topics: Animals; Carbon-Sulfur Lyases; Clinical Trials, Phase I as Topic; Cloning, Molecular; Combined Modality Therapy; Humans; Macaca; Methionine; Mice; Molecular Targeted Therapy; Neoplasms; Pseudomonas putida; Recombinant Proteins | 2015 |
Methionine restriction beyond life-span extension.
Topics: Adiposity; Animals; Bone and Bones; Caloric Restriction; Diet; Disease Progression; Epigenesis, Genetic; Glucose; Humans; Life Expectancy; Lipid Metabolism; Liver; Methionine; Myocardium; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2016 |
[Methionine metabolism regulates biotransformation of glucose via protein arginine methylation in cancer cells].
Topics: Animals; Arginine; Glucose; Humans; Methionine; Methylation; Neoplasms; Proteins | 2016 |
Pleiotropic responses to methionine restriction.
Topics: Aging; Animals; Bone Development; Caenorhabditis elegans; Cardiovascular System; Drosophila melanogaster; Epithelial Cells; Gene Expression Regulation; Humans; Longevity; Methionine; Neoplasms; Stress, Physiological; Tight Junctions; Yeasts | 2017 |
Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Death; Dimethyl Sulfoxide; Disulfides; Humans; Methionine; Neoplasms; Organoselenium Compounds; Oxidants; Reactive Oxygen Species; Selenium; Sulfinic Acids; Sulfones; Sulfur | 2010 |
Targeting methionine auxotrophy in cancer: discovery & exploration.
Topics: Animals; Antineoplastic Agents; Bioengineering; Cell Line, Tumor; Erythrocytes; Humans; Immune System; Medical Oncology; Methionine; Mice; Models, Biological; Neoplasm Transplantation; Neoplasms; Polyethylene Glycols; Pseudomonas putida; Rats | 2012 |
Application of metabolic PET imaging in radiation oncology.
Topics: Acetates; Carbon Radioisotopes; Carcinoma; Choline; Confounding Factors, Epidemiologic; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Inflammation; Lymphoma; Male; Methionine; Molecular Imaging; Neoplasms; Organ Specificity; Positron-Emission Tomography; Radiation Oncology; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted | 2012 |
A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension.
Topics: Animals; Carbon-Sulfur Lyases; Diet; Folic Acid; Humans; Life Expectancy; Methionine; Neoplasms; Phenotype; Purine-Nucleoside Phosphorylase | 2012 |
Histone methyltransferases, diet nutrients and tumour suppressors.
Topics: Amino Acid Sequence; Diet; Folic Acid Deficiency; Forecasting; Genes, Tumor Suppressor; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Neoplasms; Protein Methyltransferases; Sequence Homology, Amino Acid | 2002 |
ETHIONINE CARCINOGENESIS.
Topics: Bacteria; Carcinogenesis; Ethionine; Humans; Liver Neoplasms; Metabolism; Methionine; Neoplasms; Neoplasms, Experimental; Pharmacology; Toxicology | 1963 |
Methionine dependency and cancer treatment.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbon-Sulfur Lyases; Clinical Trials, Phase I as Topic; Homocysteine; Humans; Methionine; Neoplasms | 2003 |
Sulfur containing amino acids and human disease.
Topics: Animals; Cysteine; Down Syndrome; Humans; Methionine; Neoplasms; Sulfur | 2004 |
Methylthioadenosine.
Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Humans; Methionine; Neoplasms; Purines; S-Adenosylhomocysteine; Thionucleosides | 2004 |
DNA methylation, cancer susceptibility, and nutrient interactions.
Topics: Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Susceptibility; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Selenium | 2004 |
Methionine-stress: a pleiotropic approach in enhancing the efficacy of chemotherapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbon-Sulfur Lyases; Humans; Methionine; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Signal Transduction | 2006 |
Importance of the trans-sulfuration pathway in cancer prevention and promotion.
Topics: Adenosylhomocysteinase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Glutathione; Humans; Methionine; Models, Molecular; Molecular Sequence Data; Neoplasms; Oxidation-Reduction; Oxidative Stress; Protein Conformation; Sulfur; Taurine | 2007 |
[Methionine dependency of cancer cells: a new therapeutic approach?].
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carbon-Sulfur Lyases; Fluorouracil; Humans; Methionine; Mice; Neoplasms | 2008 |
Dehydroascorbic acid as an anti-cancer agent.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Dehydroascorbic Acid; Homocysteine; Humans; Methionine; Mice; Neoplasms | 2008 |
Methylenetetrahydrofolate reductase (MTHFR): a novel target for cancer therapy.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Delivery Systems; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oligonucleotides, Antisense | 2008 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Positron emission tomography in the study of human tumors.
Topics: Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Cerebrovascular Circulation; Female; Glucose; Humans; Methionine; Neoplasms; Oxygen Consumption; Sarcoma; Soft Tissue Neoplasms; Tomography, Emission-Computed | 1984 |
Methionine dependence in cancer cells - a review.
Topics: Animals; Carbon-Sulfur Lyases; Cell Division; Cell Line; Cell Transformation, Neoplastic; Homocysteine; Humans; Methionine; Neoplasms; Neoplasms, Experimental | 1982 |
Lipotrope deficiency and persistent changes in DNA methylation. Lipotrope deficiency and DNA methylation.
Topics: Animals; Choline Deficiency; DNA; Folic Acid Deficiency; Humans; Lipid Metabolism; Liver; Methionine; Methylation; Neoplasms; Vitamin B 12 Deficiency | 1995 |
Methyl donors in the diet and responses to chemical carcinogens.
Topics: Animals; Carcinogens; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms, Experimental; Methionine; Methylation; Neoplasms | 1995 |
Positron emission tomography in oncology.
Topics: Carbon Radioisotopes; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Tomography, Emission-Computed | 1994 |
Methionine metabolism: a window on carcinogenesis?
Topics: Cell Transformation, Neoplastic; DNA Damage; DNA Repair; Humans; Methionine; Neoplasms; Oncogene Proteins | 1993 |
[Cancer diagnosis with positron emission tomography (PET)].
Topics: Carbon Radioisotopes; Clinical Trials as Topic; Deoxyglucose; Diagnosis, Differential; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Tomography, Emission-Computed | 1996 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms | 1996 |
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease.
Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins | 1997 |
[11C-methionine: an effective radio-tracer for PET scan in the detection of tumors of low proliferating capacity].
Topics: Adult; Aged; Carbon Radioisotopes; Female; Humans; Male; Methionine; Middle Aged; Neoplasms; Tomography, Emission-Computed | 1997 |
Application of methionine-free nutrition as an anticancer treatment.
Topics: Cell Division; Drug Carriers; Humans; Methionine; Neoplasms; Nutritional Physiological Phenomena | 1999 |
Relevance of positron emission tomography (PET) in oncology.
Topics: Carbon Radioisotopes; Fluorides; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Magnetic Resonance Imaging; Methionine; Misonidazole; Neoplasm Staging; Neoplasms; Radioisotopes; Radiopharmaceuticals; Sensitivity and Specificity; Thymidine; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1999 |
[Theoretical basis for low-dose CDDP/5-FU therapy].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Stomach Neoplasms | 1999 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; Dietary Proteins; Endocrine System Diseases; Female; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Intestinal Diseases; Life Style; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Niacin; Nitrous Oxide; Norway; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Renal Insufficiency; Smoking; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Radiolabeled amino acids: basic aspects and clinical applications in oncology.
Topics: Amino Acids; Brain Neoplasms; Breast Neoplasms; Carbon Radioisotopes; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Lymphoma; Methionine; Methyltyrosines; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Tyrosine | 2001 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
Can dietary methionine restriction increase the effectiveness of chemotherapy in treatment of advanced cancer?
Topics: Animals; Antineoplastic Agents; Drug Synergism; Humans; Methionine; Neoplasm Metastasis; Neoplasms; Prostate-Specific Antigen; Safety; Treatment Outcome | 2001 |
[Positron emission tomography (PET) in oncology (Part I)].
Topics: Abdomen; Animals; Bone and Bones; Carbon Radioisotopes; Diagnosis, Differential; Energy Metabolism; Fasting; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose Transporter Type 1; Head; Humans; Image Processing, Computer-Assisted; Methionine; Mice; Monosaccharide Transport Proteins; Muscles; Neoplasm Proteins; Neoplasms; Pelvis; Radiopharmaceuticals; Thorax; Thyroid Gland; Tissue Distribution; Tomography, Emission-Computed | 2002 |
From tumor biology to clinical Pet: a review of positron emission tomography (PET) in oncology.
Topics: Amino Acids; Cell Hypoxia; Fluorodeoxyglucose F18; Glucose; Humans; Methionine; Models, Chemical; Neoplasm Recurrence, Local; Neoplasms; Radiopharmaceuticals; Tomography, Emission-Computed; Treatment Outcome; Whole-Body Counting | 2001 |
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1976 |
PET scanning in oncology.
Topics: Deoxyglucose; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Tomography, Emission-Computed | 1992 |
Unbalanced transmethylation and the perturbation of the differentiated state leading to cancer.
Topics: Animals; DNA, Neoplasm; Genotype; Humans; Methionine; Methylation; Neoplasms | 1990 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
[Potential use of positron-emission tomography in clinical oncology].
Topics: Carbon Radioisotopes; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fucose; Humans; Methionine; Neoplasms; Tomography, Emission-Computed | 1988 |
Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms | 1974 |
3 trial(s) available for methionine and Neoplasms
| Article | Year |
|---|---|
Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine.
Topics: Carbon-Sulfur Lyases; Fermentation; Humans; Infusions, Intravenous; Methionine; Neoplasm Staging; Neoplasms; Pilot Projects | 2019 |
Nutrient intake and nutritional indexes in adults with metastatic cancer on a phase I clinical trial of dietary methionine restriction.
Topics: Adult; Energy Intake; Humans; Methionine; Neoplasm Metastasis; Neoplasms; Weight Loss | 2002 |
[11C-methionine: an effective radio-tracer for PET scan in the detection of tumors of low proliferating capacity].
Topics: Adult; Aged; Carbon Radioisotopes; Female; Humans; Male; Methionine; Middle Aged; Neoplasms; Tomography, Emission-Computed | 1997 |
163 other study(ies) available for methionine and Neoplasms
| Article | Year |
|---|---|
Hypoxia regulates overall mRNA homeostasis by inducing Met
Topics: A549 Cells; Argonaute Proteins; Cell Hypoxia; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Silencing; HEK293 Cells; HeLa Cells; Homeostasis; Humans; Hypoxia; Methionine; MicroRNAs; Neoplasms; PC-3 Cells; RNA Stability; RNA, Messenger; Ubiquitination | 2021 |
Cysteine Restriction in Murine L929 Fibroblasts as an Alternative Strategy to Methionine Restriction in Cancer Therapy.
Topics: Animals; Caloric Restriction; Cell Line; Cysteine; Diet; Fibroblasts; Methionine; Mice; Neoplasms | 2021 |
Methionine synthase supports tumour tetrahydrofolate pools.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Methylation; Mutation; Neoplasms; Purines; Tetrahydrofolates; Vitamin B 12 Deficiency | 2021 |
Low Energy Status under Methionine Restriction Is Essentially Independent of Proliferation or Cell Contact Inhibition.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Cell Proliferation; Contact Inhibition; Methionine; Mice; Neoplasms | 2022 |
Methionine deficiency facilitates antitumour immunity by altering m
Topics: Animals; CD8-Positive T-Lymphocytes; Methionine; Methylation; Mice; Neoplasms; Programmed Cell Death 1 Receptor; Racemethionine | 2023 |
Autophagy-inducing nutritional interventions in experimental and clinical oncology.
Topics: Autophagy; Carcinogenesis; Humans; Medical Oncology; Methionine; Micronutrients; Neoplasms; Niacinamide; Spermidine | 2022 |
Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study.
Topics: Animals; Eating; Female; Folic Acid; Methionine; Neoplasms; Postmenopause; Prospective Studies; Racemethionine; Risk Factors; Vitamin B 12 | 2022 |
Chemoselective Methionine Labelling of Recombinant Trastuzumab Shows High In Vitro and In Vivo Tumour Targeting.
Topics: Alkynes; Animals; Antibodies, Monoclonal; Azides; Humans; Methionine; Neoplasms; Racemethionine; Trastuzumab | 2023 |
Elevated Methionine Flux Drives Pyroptosis Evasion in Persister Cancer Cells.
Topics: Apoptosis; Cell Death; Humans; Inflammasomes; Methionine; Neoplasms; Pyroptosis; Racemethionine | 2023 |
Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.
Topics: Amino Acid Transport Systems; Amino Acids; Humans; Large Neutral Amino Acid-Transporter 1; Methionine; Neoplasms; Polymers; Racemethionine; Sulfur | 2023 |
Labeling Assembly of Hydrophilic Methionine into Nanoparticle for Mild-Heat Mediated Immunometabolic Therapy.
Topics: Amino Acids; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Hot Temperature; Humans; Methionine; Nanoparticles; Neoplasms; Racemethionine | 2023 |
Pharmacokinetic/pharmacodynamic model of a methionine starvation based anti-cancer drug.
Topics: Animals; Antineoplastic Agents; Erythrocytes; Humans; Methionine; Mice; Neoplasms; Racemethionine | 2023 |
Selective Methionine Pool Exhaustion Mediated by a Sequential Positioned MOF Nanotransformer for Intense Cancer Immunotherapy.
Topics: Antineoplastic Agents; Humans; Immunotherapy; Metal-Organic Frameworks; Methionine; Neoplasms; Polyamines; Racemethionine | 2023 |
Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells.
Topics: AMP-Activated Protein Kinases; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Methionine; Mice; Mice, Knockout; Neoplasms; Programmed Cell Death 1 Receptor; Racemethionine; Up-Regulation | 2023 |
Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models.
Topics: Animals; Humans; Methionine; Models, Animal; Neoplasms; Racemethionine; Salmonella typhimurium | 2023 |
Clinical decision-making based on 11C-methionine PET in recurrent Cushing's disease with equivocal MRI findings.
Topics: Carbon Radioisotopes; Clinical Decision-Making; Female; Humans; Magnetic Resonance Imaging; Male; Methionine; Neoplasms; Pituitary ACTH Hypersecretion; Positron-Emission Tomography; Racemethionine; Retrospective Studies | 2023 |
A bimetallic nanoplatform for STING activation and CRISPR/Cas mediated depletion of the methionine transporter in cancer cells restores anti-tumor immune responses.
Topics: Animals; CD8-Positive T-Lymphocytes; CRISPR-Cas Systems; Female; Immunity; Immunotherapy; Methionine; Mice; Neoplasms | 2023 |
Methionine and H
Topics: Humans; Methionine; Neoplasms; Racemethionine | 2023 |
Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota.
Topics: Animals; Female; Gastrointestinal Microbiome; Hydrogen Sulfide; Male; Methionine; Mice; Neoplasms; Racemethionine; Sulfur | 2023 |
Site-Specific
Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Gallium Radioisotopes; Immunoconjugates; Methionine; Mice; Neoplasms; Positron-Emission Tomography; Racemethionine; Tissue Distribution; Trastuzumab; Zirconium | 2023 |
Methionine restriction sensitizes cancer cells to immunotherapy.
Topics: Apoptosis; Humans; Immunotherapy; Methionine; Neoplasms; Racemethionine | 2023 |
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden | 2019 |
Novel radiopharmaceutical (Technetium-99m)-(DOTA-NHS-ester)-Methionine as a SPECT-CT tumor imaging agent.
Topics: Animals; Biological Transport; Cell Survival; Contrast Media; Esters; HEK293 Cells; Humans; Male; MCF-7 Cells; Methionine; Mice; Neoplasms; Radiopharmaceuticals; Succinimides; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2020 |
The Transsulfuration Pathway Makes, the Tumor Takes.
Topics: Cysteine; Humans; Methionine; Methylation; Neoplasms | 2019 |
Development of ROS-responsive amino acid-based poly(ester amide) nanoparticle for anticancer drug delivery.
Topics: Antineoplastic Agents; Delayed-Action Preparations; Drug Delivery Systems; HeLa Cells; Humans; Methionine; Nanoparticles; Neoplasms; PC-3 Cells; Polyesters; Reactive Oxygen Species; Xanthones | 2021 |
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cysteine; Female; Gene Knockout Techniques; Humans; Metabolic Networks and Pathways; Methionine; Mice; Neoplasms; Polyamines; Purine-Nucleoside Phosphorylase; Reactive Oxygen Species; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Methio "mine"! Cancer cells steal methionine and impair CD8 T-cell function.
Topics: CD8-Positive T-Lymphocytes; Histones; Humans; Methionine; Methylation; Neoplasms; STAT5 Transcription Factor | 2020 |
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Topics: Amino Acid Transport System L; Animals; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Epigenesis, Genetic; Female; Histones; Humans; Methionine; Methylation; Mice; Neoplasms; Receptors, Antigen, T-Cell; STAT5 Transcription Factor | 2020 |
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity.
Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation; Epigenesis, Genetic; Folic Acid; Glutathione; Humans; Methionine; Models, Biological; Neoplasms; Phenotype; Polyamines; Serine; Taurine; Uric Acid | 2021 |
A Tug-of-War Over Methionine.
Topics: Histones; Methionine; Methylation; Neoplasms; S-Adenosylmethionine; T-Lymphocytes | 2020 |
Potential inhibitors of methionine aminopeptidase type II identified via structure-based pharmacophore modeling.
Topics: Aminopeptidases; Humans; Methionine; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms | 2022 |
Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6.
Topics: Animals; Antineoplastic Agents; Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Delivery Systems; Erythrocytes; Humans; Male; Methionine; Mice, Nude; Neoplasms; Pyridoxal Phosphate; Pyridoxine; Recombinant Proteins; Tumor Burden | 2017 |
[A new link between high homocysteine levels, cancers and neurodegenerative diseases].
Topics: Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Methionine; Neoplasms; Neurodegenerative Diseases; Risk Factors | 2017 |
Synthesis, Stability and Relaxivity of TEEPO-Met: An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging.
Topics: Animals; Contrast Media; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Heterocyclic Compounds; Humans; Magnetic Resonance Imaging; Methionine; Molecular Structure; Neoplasms; Phantoms, Imaging; Piperidines | 2018 |
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width.
Topics: Animals; Gene Expression Profiling; Genomics; HCT116 Cells; Histone Code; Histones; Humans; Liver; Lysine; Male; Methionine; Methylation; Mice, Inbred C57BL; Neoplasms | 2018 |
Methionine-Decorated Near Infrared Fluorescent Probe for Prolonged Tumor Imaging.
Topics: Amino Acid Transport System y+; Animals; Cell Line, Tumor; Fluorescent Dyes; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Intravital Microscopy; Materials Testing; Methionine; Mice; Mice, Inbred ICR; Mice, Nude; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Probes; Neoplasms; Time Factors; Xenograft Model Antitumor Assays | 2018 |
Cancer cell specific fluorescent methionine protected gold nanoclusters for in-vitro cell imaging studies.
Topics: Amino Acid Transport System y+L; Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Fluorescence; Fluorescent Dyes; Gold; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Methionine; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Particle Size; Temperature | 2018 |
Induced Pluripotent Stem Cell Elimination in a Cell Sheet by Methionine-Free and 42°C Condition for Tumor Prevention.
Topics: Carcinogenesis; Cell Culture Techniques; Cell Line; Fibroblasts; Humans; Induced Pluripotent Stem Cells; Methionine; Myocytes, Cardiac; Neoplasms; Temperature; Tissue Engineering | 2018 |
Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry.
Topics: Amino Acids; Carbon; Carbon Isotopes; Cell Line, Tumor; Gas Chromatography-Mass Spectrometry; Glucose; Glycine; Humans; Methionine; Neoplasms; Serine | 2019 |
Peptide-Aptamer Coassembly Nanocarrier for Cancer Therapy.
Topics: Alkylation; Aptamers, Nucleotide; Cell Line, Tumor; Drug Carriers; Humans; Methionine; Nanoparticles; Neoplasms; Peptides; RNA, Small Interfering; RNAi Therapeutics | 2019 |
Methods to Study the Role of Methionine-Restricted Diet and Methioninase in Cancer Growth Control.
Topics: Animals; Biochemistry; Carbon-Sulfur Lyases; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Diet; Female; Male; Methionine; Mice, Nude; Mice, SCID; Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Altered Methionine Metabolism in Cancer Cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Homocysteine; Humans; Methionine; Methylation; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 2019 |
Linkage of Methionine Dependence and Other Features of Malignancy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Line, Tumor; Cell Proliferation; Humans; Methionine; Methylation; Neoplasms; Rats | 2019 |
Isolation and Characterization of Methionine-Independent Clones from Methionine-Dependent Cancer Cells.
Topics: Cell Adhesion; Cell Line, Transformed; Cell Line, Tumor; Cell Separation; Cell Survival; Clone Cells; Humans; Luminescent Measurements; Methionine; Neoplasms | 2019 |
Efficacy of Methionine-Restricted Diets on Cancers In Vivo.
Topics: Animals; Body Weight; Cell Cycle; Diet; DNA; Methionine; Mice, Nude; Neoplasms; Sarcoma; Xenograft Model Antitumor Assays | 2019 |
Dietary Methionine Restriction-Based Cancer Chemotherapy in Rodents.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cisplatin; Coculture Techniques; Diet; Doxorubicin; Ethionine; Fluorouracil; Humans; Male; Methionine; Mice, Nude; Neoplasm Metastasis; Neoplasms; Parenteral Nutrition; Rats; Sarcoma, Yoshida; Vincristine | 2019 |
Clinical Studies of Methionine-Restricted Diets for Cancer Patients.
Topics: Aged; Clinical Trials as Topic; Diet; Female; Humans; Male; Methionine; Middle Aged; Neoplasms; Parenteral Nutrition, Total | 2019 |
Total Methionine Restriction Treatment of Cancer.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Choline; Homocysteine; Humans; Liver; Methionine; Mice, Nude; Neoplasms; Temozolomide; Xenograft Model Antitumor Assays | 2019 |
L-[Methyl-
Topics: Cell Line, Tumor; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Positron-Emission Tomography | 2019 |
Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer?
Topics: Aneuploidy; DNA Methylation; G2 Phase; Genomic Instability; Glucose; Glycolysis; Humans; Methionine; Neoplasms; S Phase; S-Adenosylmethionine | 2019 |
Use of
Topics: Carbon Isotopes; Cell Line, Tumor; Chromatography, Liquid; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Hydrolysis; Methionine; Neoplasms; Nitrogen Isotopes; RNA; Serine; Tandem Mass Spectrometry | 2019 |
Nutrient availability shapes methionine metabolism in p16/
Topics: Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Humans; Methionine; Neoplasms; Nutrients; Sequence Deletion | 2019 |
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
Topics: Epigenesis, Genetic; Humans; Methionine; Methylation; Models, Genetic; Neoplasms; Niacinamide; Nicotinamide N-Methyltransferase | 2013 |
Evaluation of the biodistribution of 11C-methionine in children and young adults.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Female; Humans; Infant; Male; Methionine; Neoplasms; Positron-Emission Tomography; Radiometry; Recurrence; Sex Factors; Tissue Distribution; Tomography, X-Ray Computed; Young Adult | 2013 |
Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme.
Topics: Amino Acid Sequence; Apoptosis; Apoptosis Regulatory Proteins; Bacillus subtilis; Caspase 1; Caspase 9; Catalytic Domain; Cell Death; HeLa Cells; Humans; Inflammation; Methionine; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neoplasms; Sequence Homology, Amino Acid | 2014 |
Metal based imaging probes of DO3A-Act-Met for LAT1 mediated methionine specific tumors: synthesis and preclinical evaluation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Contrast Media; Coordination Complexes; Heterocyclic Compounds, 1-Ring; Humans; Large Neutral Amino Acid-Transporter 1; Magnetic Resonance Imaging; Methionine; Mice, Nude; Molecular Imaging; Multimodal Imaging; Neoplasms; Positron-Emission Tomography; Predictive Value of Tests; Rabbits; Radiopharmaceuticals; Tissue Distribution | 2015 |
LAT1 targeted delivery of methionine based imaging probe derived from M(III) metal ions for early diagnosis of proliferating tumours using molecular imaging modalities.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Early Detection of Cancer; Female; Gallium Radioisotopes; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Male; Methionine; Mice, Inbred BALB C; Mice, Nude; Molecular Imaging; Multimodal Imaging; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Pentetic Acid; Rabbits; Radionuclide Imaging; Rats; Rats, Wistar | 2015 |
Kinase regulation by hydrophobic spine assembly in cancer.
Topics: Adenosine Triphosphate; Allosteric Site; Catalysis; ErbB Receptors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Methionine; Models, Molecular; Mutation; Neoplasms; Phosphotransferases; Protein Structure, Secondary; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-abl | 2015 |
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
Topics: Alcohol Oxidoreductases; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; DNA-Binding Proteins; Glutamine; Glycolysis; Homeostasis; Humans; Hydrogen-Ion Concentration; Methionine; Mice; Mice, Nude; Mitochondrial Proteins; Models, Biological; Neoplasms; Sirtuins; Xenograft Model Antitumor Assays | 2015 |
Methionine to isothreonine conversion as a source of false discovery identifications of genetically encoded variants in proteogenomics.
Topics: Amino Acid Substitution; Artifacts; Cell Line, Tumor; False Positive Reactions; Genetic Markers; Genetic Variation; Humans; Methionine; Neoplasms; Proteome; Proteomics; Reproducibility of Results; Sensitivity and Specificity; Threonine | 2015 |
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Homocysteine; Humans; Methionine; Neoplasms; RNA; S-Adenosylmethionine; Serine; Stress, Physiological | 2016 |
Chasing One-Carbon Units to Understand the Role of Serine in Epigenetics.
Topics: Adenosine Triphosphate; DNA Methylation; Humans; Methionine; Neoplasms; Serine | 2016 |
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Topics: Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Deoxyadenosines; Gene Deletion; Humans; Methionine; Neoplasms; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; RNA, Small Interfering; Thionucleosides | 2016 |
Genetics: Common co-deletion isn't a silent passenger.
Topics: Cyclin-Dependent Kinase Inhibitor p16; Humans; Methionine; Neoplasms; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase | 2016 |
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).
Topics: Alcohol Oxidoreductases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Drug Design; Halogenation; Humans; Methionine; Models, Molecular; Neoplasms; Oximes; Phenylpropionates; Structure-Activity Relationship | 2016 |
Stabilizing the cold plasma-stimulated medium by regulating medium's composition.
Topics: Antineoplastic Agents; Culture Media; Cysteine; Free Radicals; Freezing; Helium; Humans; Hydrogen Peroxide; Methionine; Neoplasms; Radiation; Tyrosine | 2016 |
Antioxidant and Antimutagenic Metabolites in Animals with Opposite Sensitivity to Tuberculosis Mycobacteria and Mutagenic Xenobiotics.
Topics: Animals; Disease Susceptibility; Ethanolamine; Ethanolamines; Glutathione; Guinea Pigs; Liver; Methionine; Mutagens; Mycobacterium tuberculosis; Neoplasms; Rats; Serine; Species Specificity; Taurine; Tuberculosis; Xenobiotics | 2016 |
Synthesis of a Novel IR-822-Met near-infrared probe for in vivo tumor diagnosis.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Nude; Neoplasms; Optical Imaging; Spectroscopy, Near-Infrared | 2017 |
Estimation of flux ratios without uptake or release data: Application to serine and methionine metabolism.
Topics: HeLa Cells; Humans; Isotope Labeling; Methionine; Models, Biological; Neoplasms; Serine | 2017 |
Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Extracellular Vesicles; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Methionine; Neoplasms; S-Adenosylmethionine | 2017 |
Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis.
Topics: Biogenic Polyamines; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Fourier Analysis; Head and Neck Neoplasms; Histamine; Humans; Lung Neoplasms; Male; Methionine; Neoplasms; Nicotinic Acids; Nucleosides; Purines; Pyridinium Compounds; Rectal Neoplasms; Ribose; Spectrometry, Mass, Electrospray Ionization | 2008 |
Molecular imaging and targeted therapies in oncology: new concepts in treatment response assessment. a collection of cases.
Topics: Aged; Antineoplastic Agents; Carbon Radioisotopes; Choline; Clinical Trials as Topic; Female; Fluorodeoxyglucose F18; Humans; Male; Methionine; Middle Aged; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed | 2008 |
Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Topics: Animals; Diet; DNA-Binding Proteins; Food; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Methionine; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; S-Adenosylmethionine; Transcription Factors | 2008 |
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amidinotransferases; Animals; Arginase; Arginine; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Creatine; Creatinine; Enzymes; Female; Gene Expression Regulation, Neoplastic; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Membrane Transport Proteins; Methionine; Mice; Muscle, Skeletal; Neoplasms; Ornithine; Ornithine Decarboxylase; Sarcoma 180 | 2008 |
Epigenetic modification of the gene for the vitamin B(12) chaperone MMACHC can result in increased tumorigenicity and methionine dependence.
Topics: Alleles; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; DNA, Complementary; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Methionine; Molecular Chaperones; Neoplasm Proteins; Neoplasms; Oxidoreductases; Transfection; Vitamin B 12 | 2009 |
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors | 2010 |
Synthesis of specific SPECT-radiopharmaceutical for tumor imaging based on methionine: 99mTc-DTPA-bis(methionine).
Topics: Adult; Aged; Animals; Biological Transport; Cell Line, Tumor; Chelating Agents; Drug Stability; Female; Humans; Kinetics; Methionine; Mice; Middle Aged; Neoplasms; Organotechnetium Compounds; Pentetic Acid; Quality Control; Rabbits; Radiochemistry; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2010 |
Non FDG PET.
Topics: Choline; Humans; Methionine; Neoplasm Staging; Neoplasms; Positron-Emission Tomography; Practice Guidelines as Topic; Radioisotopes; Radiopharmaceuticals | 2010 |
Chemical genetic screening for compounds that preferentially inhibit growth of methylthioadenosine phosphorylase (MTAP)-deficient Saccharomyces cerevisiae.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Methionine; Neoplasms; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae; Small Molecule Libraries; Thiadiazines | 2011 |
Dynamic 11C-methionine PET analysis has an additional value for differentiating malignant tumors from granulomas: an experimental study using small animal PET.
Topics: Animals; Diagnosis, Differential; Granuloma; Male; Methionine; Neoplasms; Positron-Emission Tomography; Rats; Rats, Wistar | 2011 |
Reactivity of a cytostatic active N,N-donor-containing dinuclear Pt(II) complex with biological relevant nucleophiles.
Topics: Antineoplastic Agents; Chelating Agents; Cytostatic Agents; Glutathione; Guanosine Monophosphate; HeLa Cells; Humans; Methionine; Neoplasms; Organoplatinum Compounds; Thiourea | 2012 |
Synthesis of a novel L-methyl-methionine-ICG-Der-02 fluorescent probe for in vivo near infrared imaging of tumors.
Topics: Amino Acid Transport System y+; Animals; Carbocyanines; Cell Death; Cell Line, Tumor; Diagnostic Imaging; Fluorescent Dyes; Humans; Indocyanine Green; Large Neutral Amino Acid-Transporter 1; Male; Methionine; Mice; Mice, Nude; Neoplasms; Reference Standards; Spectroscopy, Near-Infrared; Xenograft Model Antitumor Assays | 2012 |
Photofrin binds to procaspase-3 and mediates photodynamic treatment-triggered methionine oxidation and inactivation of procaspase-3.
Topics: Amino Acid Sequence; Apoptosis; Caspase 3; Catalytic Domain; Cell Line, Tumor; Dihematoporphyrin Ether; Humans; Jurkat Cells; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasms; Nitrogen Isotopes; Oxidation-Reduction; Oxygen Isotopes; Photochemotherapy; Photosensitizing Agents; Protein Binding; Protein Processing, Post-Translational; Recombinant Proteins; Tandem Mass Spectrometry; Ultraviolet Rays | 2012 |
A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Colon; Colonic Neoplasms; Dendrimers; Humans; Methionine; Mice; Mice, Inbred BALB C; Neoplasms; Organotechnetium Compounds; Pentetic Acid; Tomography, Emission-Computed, Single-Photon | 2013 |
Incorporation of labeled methionine in vitro by tissues of C3H mice.
Topics: Animals; In Vitro Techniques; Methionine; Mice; Mice, Inbred C3H; Neoplasms; Vectorcardiography | 1953 |
[Distribution of methionine labeled with radiosulfur in the organism of a tumor-bearing mouse].
Topics: Animals; Methionine; Mice; Neoplasms | 1955 |
[Effect of methionine labeled with radiosulfur on growth of certain murine tumors].
Topics: Animals; Methionine; Mice; Neoplasms; Neoplasms, Experimental | 1955 |
The effect of methionine supplementation upon the tumor-host relationship in the rat.
Topics: Animals; Diet; Dietary Supplements; Methionine; Neoplasms; Neoplasms, Experimental; Rats | 1956 |
The effect of excess dietary methionine on the rate of growth of RD3 sarcoma.
Topics: Animals; Methionine; Neoplasms; Neoplasms, Experimental; Sarcoma | 1956 |
Characteristics of the inhibition by ethionine of the incorporation of methionine into proteins of the Ehrlich ascites carcinoma in vitro.
Topics: Ascites; Carcinoma; Ethionine; In Vitro Techniques; Methionine; Neoplasms; Proteins | 1957 |
The uptake of S35 from methionine by plasma proteins in proteindepleted and tumor-bearing dogs.
Topics: Animals; Blood Proteins; Dogs; Lymphatic Diseases; Methionine; Neoplasms; Sulfur | 1958 |
Effects of age, sex, strain, and methionine analogs on the nonprotein amino acids in the liver of normal and tumorous rats.
Topics: Amino Acids; Animals; Liver; Methionine; Neoplasms; Organic Chemicals; Rats | 1958 |
The effect of implanted tumors on the oxidation of formate and of the methyl group of methionine in mouse liver.
Topics: Encephalomyelitis; Formates; Liver; Methionine; Neoplasms; Oxidation-Reduction | 1958 |
Autoradiographic evidence of distribution of 35S-methionine in Ehrlich ascites cells.
Topics: Ascites; Encephalomyelitis; Methionine; Neoplasms | 1958 |
[Combined effect of radioactive methionine and of sarcolysin on animal tumors].
Topics: Animals; Mechlorethamine; Melphalan; Methionine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds | 1959 |
Synthesis of 4-thiamethionine and its effect on energy metabolism and amino acid incorporation into protein of Ehrlich ascites tumour cells.
Topics: Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Energy Metabolism; Methionine; Neoplasms; Proteins | 1961 |
Incorporation of S35 from L-methionine in tumor-bearing and protein-depleted rats.
Topics: Animals; Methionine; Neoplasms; Protein Deficiency; Proteins; Rats | 1961 |
Factors controlling the uptake and retention of methionine and ethionine by Ehrlich ascites carcinoma cells.
Topics: Ascites; Ethionine; Methionine; Neoplasms | 1961 |
Effects of nitrogen mustards on the incorporation of amino acids into the proteins of tumors and other tissues; the mustard derivative of serine.
Topics: Amino Acids; Animals; Carcinoma; Carcinoma 256, Walker; Humans; Mechlorethamine; Methionine; Mustard Plant; Neoplasms; Nitrogen Mustard Compounds; Proteins; Serine | 1963 |
[Research on the higher homologues of methionine. XX. Action of isopropylhomocysteine isomers on HeLa strains].
Topics: HeLa Cells; Humans; Isomerism; Methionine; Neoplasms; Research; Tissue Culture Techniques | 1962 |
PANCREATIC UPTAKE OF SE75--SELENOMETHIONINE.
Topics: Amino Acids; Animals; Haplorhini; Methionine; Neoplasms; Pancreas; Pancreatic Neoplasms; Radioisotopes; Radionuclide Imaging; Research; Selenium; Selenomethionine | 1963 |
METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION.
Topics: Adrenalectomy; Carbon Isotopes; Carcinoma, Hepatocellular; Cortisone; Hypophysectomy; Liver; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; Oxygenases; Phenylalanine; Portacaval Shunt, Surgical; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tryptophan; Tryptophan Oxygenase | 1964 |
RELATION BETWEEN EXPERIMENTAL HEPATOCARCINOGENESIS AND CIRRHOSIS.
Topics: Amino Alcohols; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver Cirrhosis; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Research; Toxicology | 1964 |
SERUM AMINOPEPTIDASE IN PREGNANCY, HYDATIFORM MOLE, AND CHORIOCARCINOMA.
Topics: Aminopeptidases; Animals; Choriocarcinoma; Clinical Enzyme Tests; Female; Humans; Hydatidiform Mole; Methionine; Moles; Neoplasms; Pharmacology; Pregnancy; Uterine Neoplasms | 1964 |
PARATHYROID SCANNING WITH SELENIUM-75 LABELLED METHIONINE.
Topics: Adenoma; Blood; Blood Proteins; Dogs; Erythrocytes; Hyperparathyroidism; Methionine; Muscles; Neoplasms; Parathyroid Neoplasms; Radioisotopes; Radionuclide Imaging; Selenium; Thyroid Gland | 1964 |
[AN ATTEMPT WITH USE OF METHIONINE IN THE TREATMENT OF LARYNGEAL PAPILLOMA].
Topics: Humans; Laryngeal Neoplasms; Methionine; Neoplasms; Papilloma; Papillomavirus Infections; Precancerous Conditions | 1964 |
ETHIONINE CARCINOGENESIS IN THE RAT.
Topics: Carbon Isotopes; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Ethionine; Glycine; Liver; Liver Neoplasms; Methionine; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; RNA; RNA, Neoplasm; Toxicology | 1965 |
The distribution of S35 from labeled DL-methionine in mice bearing carcinoma of the breast, neoplasms of the hematopoietic system, or liver abscesses.
Topics: Animals; Breast; Carcinoma; Hematopoietic System; Liver Abscess; Methionine; Mice; Neoplasms; Sulfur; Sulfur Radioisotopes | 1951 |
The incorporation of methionine S35 into the proteins of Jensen rat sarcoma cells after irradiation of the tumour.
Topics: Animals; Methionine; Neoplasms; Proteins; Rats; Sarcoma, Experimental; X-Rays | 1952 |
Potentiated antitumor effects of a combination therapy with a farnesyltransferase inhibitor L-744,832 and butyrate in vitro.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Butyrates; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Drug Therapy, Combination; Farnesyltranstransferase; Humans; Methionine; Neoplasms; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2004 |
An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice.
Topics: Amino Acid Substitution; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Collagen; Enzyme Activation; Extracellular Matrix; Female; Genetic Therapy; Genetic Vectors; Glutamine; Hepatocyte Growth Factor; Humans; Lentivirus; Methionine; Mice; Mice, Nude; Mitosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Protein Engineering; Protein-Tyrosine Kinases; Recombinant Proteins; Transduction, Genetic; Transplantation, Heterologous; Tumor Burden | 2004 |
Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cystathionine beta-Synthase; Ferredoxin-NADP Reductase; Gene Expression Profiling; Homocysteine; Humans; Methionine; NADPH-Ferrihemoprotein Reductase; Neoplasms | 2005 |
The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients.
Topics: Aged; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Female; Genotype; Humans; Male; Methionine; Middle Aged; Morphine; Narcotics; Neoplasms; Pain; Pain Measurement; Pain Threshold; Pharmacogenetics; Polymorphism, Genetic; Retrospective Studies; Statistics, Nonparametric; Valine | 2005 |
Methionine dependence of tumours: a biochemical strategy for optimizing paclitaxel chemosensitivity in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Combinations; Drug Screening Assays, Antitumor; Humans; Methionine; Mice; Neoplasms; Paclitaxel; Rats; Vinblastine | 2006 |
The Bence-Jones protein of multiple myelomatosis: its methionine content and its possible significance in relation to the aetiology of the disease.
Topics: Bence Jones Protein; Humans; Methionine; Multiple Myeloma; Neoplasms | 1949 |
Clinical PET in oncology: not only FDG.
Topics: Acetates; Carbon Radioisotopes; Choline; Fluorodeoxyglucose F18; Gallium Radioisotopes; Humans; Medical Oncology; Methionine; Neoplasms; Organometallic Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity | 2006 |
Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.
Topics: Acetylation; Alkyl and Aryl Transferases; Antineoplastic Agents; Benzamides; Enzyme Inhibitors; Farnesyltranstransferase; Histone Acetyltransferases; Histone Deacetylase 1; Histone Deacetylases; Histones; Humans; Methionine; Neoplasms; Promoter Regions, Genetic; Protein Processing, Post-Translational; Reverse Transcriptase Polymerase Chain Reaction; rhoB GTP-Binding Protein; RNA, Neoplasm; Tumor Cells, Cultured; Up-Regulation | 2007 |
The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study.
Topics: Cardiovascular Diseases; Catechol O-Methyltransferase; Diabetes Mellitus; Female; Follow-Up Studies; Genotype; Humans; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Genetic; Survival Analysis; Valine | 2007 |
Lipotropes, immunocompetence, and cancer.
Topics: Animals; Choline Deficiency; Disease Susceptibility; Folic Acid Deficiency; Immunocompetence; Lipotropic Agents; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms; Rats; Rats, Inbred F344; Rats, Inbred Strains; Vitamin B 12 Deficiency | 1983 |
Biological evaluation of radiolabeled D-methionine as a parent compound in potential nuclear imaging.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Isomerism; Methionine; Mice; Neoplasms; Pancreas; Radionuclide Imaging; Tissue Distribution | 1984 |
Methionine synthesis from 5'-methylthioadenosine by tumour cells.
Topics: Adenosine; Animals; Carbon Radioisotopes; Cell Line; Cells, Cultured; Deoxyadenosines; Humans; Kinetics; Leukemia; Methionine; Mice; Neoplasms; Thionucleosides; Urinary Bladder Neoplasms | 1983 |
The metabolic defect of methionine dependence occurs frequently in human tumor cell lines.
Topics: Cell Line; Culture Media; Homocysteine; Humans; Methionine; Neoplasms | 1983 |
Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines.
Topics: Cell Line; Homocysteine; Humans; Methionine; Models, Biological; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Regulation of de novo biosynthesis of thyrotropin in normal, hyperplastic, and neoplastic thyrotrophs.
Topics: Animals; Antibody Specificity; Cells, Cultured; Female; Hyperplasia; Methionine; Neoplasms; Pituitary Gland; Precipitin Tests; Rabbits; Rats; Thyrotropin; Thyrotropin-Releasing Hormone | 1981 |
Apparent methionine auxotrophy of some tumour cell lines may be linked to impaired amino acid transport.
Topics: Animals; Biological Transport; Carcinoma 256, Walker; Cell Division; Cell Line; Embryo, Mammalian; Fibroblasts; Humans; Leukemia, Experimental; Lysine; Methionine; Mice; Neoplasms; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Effect of methionine replacement by homocysteine on the growth of cells.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Culture Media; Homocysteine; Humans; Methionine; Mice; Neoplasms; Rats | 1980 |
Effect of nitrous oxide on human bone marrow cells and its synergistic effect with methionine and methotrexate on functional folate deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bone Marrow; Deoxyuridine; DNA; Drug Synergism; Folic Acid Antagonists; Humans; Methionine; Methotrexate; Methyltransferases; Neoplasms; Nitrous Oxide; Pteroylpolyglutamic Acids; Time Factors | 1981 |
Activation of the leukocyte plastin gene occurs in most human cancer cells.
Topics: Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Primers; Escherichia coli; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Membrane Glycoproteins; Methionine; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Neoplasms; Phosphoproteins; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1994 |
Re: "Arsenic ingestion and internal cancers: a review".
Topics: Arsenic; Arterial Occlusive Diseases; Diet; Female; Humans; Male; Methionine; Neoplasms; Peripheral Vascular Diseases; Zinc | 1993 |
Expression of the biochemical defect of methionine dependence in fresh patient tumors in primary histoculture.
Topics: Cell Count; Cell Cycle; Culture Media; Fibroblasts; G1 Phase; Humans; Methionine; Neoplasms; Tumor Cells, Cultured | 1993 |
Positron emission tomography in oncology: the most sophisticated imaging technology.
Topics: Carbon Radioisotopes; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Methionine; Neoplasms; Tomography, Emission-Computed | 1997 |
Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.
Topics: Animals; Carbon-Sulfur Lyases; Cell Division; Half-Life; Humans; In Vitro Techniques; Male; Methionine; Mice; Neoplasms; Polyethylene Glycols; Rats; Recombinant Proteins; Tissue Distribution; Tumor Cells, Cultured | 1998 |
Cobalamin metabolism in methionine-dependent human tumour and leukemia cell lines.
Topics: Carbon Radioisotopes; Culture Media; Humans; Leukemia; Melanoma; Methionine; Neoplasms; Propionates; Tetrahydrofolates; Tumor Cells, Cultured; Vitamin B 12 | 1998 |
[Positron emission tomography ia an effective tool in modern oncology].
Topics: Fluorodeoxyglucose F18; Humans; Methionine; Neoplasm Metastasis; Neoplasms; Tomography, Emission-Computed | 1999 |
Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Brain Neoplasms; Carcinoma, Small Cell; Cell Division; Colonic Neoplasms; Dietary Supplements; Drug Resistance, Multiple; Ethionine; Female; Genes, MDR; Glioma; Glutathione; Homocysteine; Humans; Lung Neoplasms; Male; Methionine; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasms; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Therapeutic targets in radiotherapy.
Topics: Alkyl and Aryl Transferases; Antibodies, Monoclonal; Antineoplastic Agents; Cell Division; Cell Hypoxia; Dose Fractionation, Radiation; Enzyme Inhibitors; ErbB Receptors; Farnesyltranstransferase; Genes, ras; Head and Neck Neoplasms; Humans; Methionine; Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Tirapazamine; Triazines; Tumor Cells, Cultured | 2001 |
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Cell Hypoxia; Enzyme Inhibitors; Farnesyltranstransferase; Gene Expression; Genes, ras; HT29 Cells; Humans; Methionine; Mice; Mice, Nude; Mutation; Neoplasms; Oxygen; ras Proteins; Xenograft Model Antitumor Assays | 2001 |
A dysmethylation syndrome, bound to folates and/or vitamin B12 and/or methionine abnormalities? Diagnosis, prevention and treatment considerations.
Topics: DNA Methylation; Folic Acid Deficiency; Hematologic Diseases; Humans; Hyperhomocysteinemia; Iatrogenic Disease; Methionine; Methylation; Neoplasms; Nervous System Diseases; Selenium; Vascular Diseases; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2001 |
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.
Topics: Animals; Biomarkers; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Intestinal Neoplasms; Methionine; Mice; Neoplasms; Precancerous Conditions; S-Adenosylhomocysteine; S-Adenosylmethionine | 2002 |
Isolation and identification of urinary beta-aspartyl dipeptides and their concentrations in human urine.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Child; Dipeptides; Female; Glutamates; Glycine; Humans; Hydrogen-Ion Concentration; Male; Methionine; Middle Aged; Neoplasms; Parenteral Nutrition, Total; Sex Factors; Threonine; Uremia | 1978 |
Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia.
Topics: Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Schizophrenia | 1975 |
[Achievements and perspectives of radioisotope diagnosis of malignant tumors (according to materials in the "Journal of Nuclear Medicine", 1974)].
Topics: Actinoid Series Elements; Animals; Antigens, Neoplasm; Bleomycin; Breast Neoplasms; Female; Gallium Radioisotopes; Humans; Indium; Iodine Radioisotopes; Isotope Labeling; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Metals, Rare Earth; Methionine; Mice; Neoplasms; Radioisotopes; Radionuclide Imaging; Selenium; Technetium; Ytterbium | 1976 |
Lessons from the study of induced alterations in amino acids in patients with cancer.
Topics: Amino Acids; Animals; Asparaginase; Cell Line; Child; Humans; Methionine; Mice; Neoplasms; Selenomethionine; T-Lymphocytes | 1979 |
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms | 1975 |
Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line.
Topics: Amino Acid Sequence; Amino Acids; Animals; B-Lymphocytes; Biopsy; Cell Line; Female; Glycosylation; Humans; Immunoenzyme Techniques; Kinetics; Methionine; Molecular Sequence Data; Neoplasms; Peptide Mapping; Phosphorus Radioisotopes; Protein-Tyrosine Kinases; Reference Values; Sequence Homology, Nucleic Acid | 1992 |
[Anticancer therapy with amino acid imbalance].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine | 1991 |
Methylthioadenosine phosphorylase deficiency in human leukemias and solid tumors.
Topics: Humans; L-Lactate Dehydrogenase; Leukemia; Methionine; Neoplasms; Pentosyltransferases; Purine-Nucleoside Phosphorylase | 1986 |
Patterns of methionine auxotrophy in normal and neoplastic cells: the methionine independence of lymphocyte mitogenesis and low frequency of the methionine-dependent phenotype in human tumors.
Topics: Adenosine; Animals; Culture Media; Deoxyadenosines; Humans; Lymphocyte Activation; Methionine; Mice; Neoplasms; Phenotype; Thionucleosides; Tumor Cells, Cultured | 1988 |
Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Culture Media; Doxorubicin; Female; Fibroblasts; Homocysteine; Humans; Male; Methionine; Neoplasms; Osteosarcoma; Prostatic Neoplasms; Vincristine | 1986 |
Imaging of human tumors and organs with N-13-labeled L-methionine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Methionine; Middle Aged; Neoplasms; Nitrogen Radioisotopes; Osteosarcoma; Radionuclide Imaging; Sarcoma; Soft Tissue Neoplasms; Tissue Distribution | 1986 |
Role of vitamin B12 and folate deficiencies in carcinogenesis.
Topics: Animals; Carcinogens; Diet; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Neoplasms, Experimental; Vitamin B 12 Deficiency | 1986 |
Altered biochemical properties of actin in normal skin fibroblasts from individuals predisposed to dominantly inherited cancers.
Topics: Actins; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Half-Life; Humans; Methionine; Molecular Weight; Neoplasms; Polymers; RNA, Messenger; Skin; Sulfur Radioisotopes; Vimentin | 1986 |
Methionine metabolism and cancer.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Gene Expression Regulation; Mammals; Methionine; Methylation; Methyltransferases; Models, Biological; Neoplasms; S-Adenosylmethionine | 1985 |
Comparison of soluble RNA methylase capacity in paired neoplastic and nonneoplastic cell lines in vitro.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Escherichia coli; Methionine; Methylation; Mice; Neoplasms; RNA, Neoplasm; RNA, Transfer; Transferases | 1969 |
Transfer RNA methylases and cancer.
Topics: Animals; Carbon Isotopes; Carcinogens; Cell Differentiation; Chromatography, Ion Exchange; Escherichia coli; Ethionine; Guanine; Humans; Kidney Neoplasms; Liver Regeneration; Methionine; Methylation; Morphogenesis; Neoplasms; Nitrosamines; Phenylalanine; Protein Biosynthesis; Rats; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Transferases | 1970 |
S-adenosylmethionine in human blood.
Topics: Adenosine; Adult; Child; Child, Preschool; Humans; Leukemia; Methionine; Methyltransferases; Neoplasms; Neuroblastoma; Radioisotope Dilution Technique; S-Adenosylmethionine | 1971 |
Clinical and experimental uses of radioisotopes in the diagnosis of cancer.
Topics: Bone Neoplasms; Brain Neoplasms; Calcium Isotopes; Cesium Isotopes; DNA; Eye Neoplasms; Fluorine; Gallium; Humans; Iodine Radioisotopes; Liver Neoplasms; Methionine; Neoplasms; Phosphorus Isotopes; Radionuclide Imaging; Rubidium; Selenium; Strontium Isotopes; Thyroid Neoplasms | 1968 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
75Se-selenomethionine uptake by malignant tumours.
Topics: Blood Specimen Collection; Bone Neoplasms; Carcinoma; Hodgkin Disease; Humans; Injections, Intravenous; Lung Neoplasms; Lymphoma, Non-Hodgkin; Methionine; Myosarcoma; Neoplasms; Radioisotopes; Radiometry; Radionuclide Imaging; Rhabdomyosarcoma; Selenium; Temporal Bone | 1968 |
[Human calcitonin. Structure of calcitonin M and D].
Topics: Amino Acid Sequence; Calcitonin; Chemical Phenomena; Chemistry; Humans; Methionine; Neoplasm Proteins; Neoplasms; Peptides; Sulfides | 1968 |
N6-(Delta 2-isopentenyl) adenosine interference with methionine metabolism in axemic cultures of mammalian cells.
Topics: Animals; Cricetinae; Culture Techniques; Depression, Chemical; Methionine; Neoplasms; Nucleosides | 1969 |
[Distribution and kinetics of selenium-75-labeled methionine in the organism].
Topics: Animals; Humans; Methionine; Neoplasms; Radionuclide Imaging; Rats; Selenium | 1965 |
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds | 1966 |