methionine has been researched along with Liver Steatosis in 340 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 88 (25.88) | 18.7374 |
1990's | 10 (2.94) | 18.2507 |
2000's | 93 (27.35) | 29.6817 |
2010's | 135 (39.71) | 24.3611 |
2020's | 14 (4.12) | 2.80 |
Authors | Studies |
---|---|
Ballentine, SJ; Brunt, EM; Davidson, NO; Molitor, EA; Newberry, EP; Soleymanjahi, S; Xie, Y | 1 |
Chen, C; Chen, J; Clayton, YD; Ding, WX; Du, Y; Friedman, JE; Gu, L; Gunewardena, S; Hasan, MN; Li, T; Lu, SC; Matye, D; Wang, H; Wang, Y | 1 |
Arshad, U; Husnain, A; Perdomo, MC; Poindexter, MB; Santos, JEP; Zimpel, R | 1 |
Kuttner, CS; Lammert, F; Mancina, R; Stokes, CS; Wagenpfeil, G | 1 |
Claudel, T; Fuchs, CD; Krivanec, S; Marschall, HU; Mlitz, V; Scharnagl, H; Stahlman, M; Steinacher, D; Stojakovic, T; Trauner, M; Wahlström, A | 1 |
da Silva, RP; Eudy, BJ; Fernandez, G; Lai, J; Mathews, CE; McDermott, CE | 1 |
Andreola, F; Argemi, J; Bataller, R; Caballeria, J; Cowart, LA; De Chiara, F; Fondevila, C; Fox, T; Frenguelli, L; Kester, M; Levi, A; Longato, L; Luong, TV; Massey, V; Mazza, G; Montefusco, D; Omenetti, S; Pinzani, M; Rombouts, K; Shanmugavelandy, SS; Zanieri, F | 1 |
Balint-Lahat, N; Ben-Ari, Z; Brzezinski, RY; Finchelman, JM; Grossman, E; Hoffer, O; Leor, J; Levin-Kotler, L; Lewis, N; Naftali-Shani, N; Ovadia-Blechman, Z; Rabin, N; Safran, M; Sternfeld, A; Tepper-Shaihov, O; Unis, R; Zimmer, Y | 1 |
Andriamihaja, M; Blachier, F; Blais, A | 1 |
Abe, A; Miyajima, K; Nakae, D; Ogawa, S; Sano, R; Suzuki-Kemuriyama, N; Uno, K; Watanabe, A; Yuki, M | 1 |
Chen, Y; Liu, Y; Qian, K; Xiong, Y; Xu, W; Zhai, T | 1 |
Ceacero-Heras, D; Córdova, S; de Medina, FS; Gámez-Belmonte, R; Hernández-Chirlaque, C; Martínez-Augustin, O; Tena-Garitaonaindia, M | 1 |
Chen, Y; Cheng, Y; Ding, W; Fan, J; Jiang, D; Lin, S; Pan, J; Zhang, J | 1 |
Baek, J; Basavarajappa, L; Hoyt, K; Parker, KJ; Poul, SS; Reddy, S; Tai, H | 1 |
Berardo, C; Cagna, M; Croce, AC; Di Pasqua, LG; Ferrigno, A; Mannucci, B; Milanesi, G; Vairetti, M | 1 |
Abe, M; Akiba, J; Hisamoto, T; Ikezono, Y; Iwamoto, H; Koga, H; Matsui, T; Nakamura, K; Nakamura, T; Torimura, T; Wada, F; Yamagishi, SI; Yoshida, T | 1 |
Cohen, DE; Hornick, JL; Nicholls, HT | 1 |
Chen, Y; Cho, GJ; Chung, HT; Joe, Y; Kim, HJ; Kim, J; Kim, SK; Kim, UH; Park, J; Park, SU; Ryter, SW; Ryu, J; Surh, YJ | 1 |
Baron, JL; Duwaerts, CC; Goodsell, A; Maher, JJ; Mattis, AN; Pierce, AA; Siao, K | 1 |
Bekpınar, S; Çevik, A; Genc, S; Gürdöl, F; Küskü-Kiraz, Z; Olgaç, V; Ünlücerci, Y; Uysal, M | 1 |
Adam, AC; Bock, C; Dahl, JA; Espe, M; Fernandes, JMO; Jakt, LM; Klughammer, J; Skjærven, KH | 1 |
Hasegawa, K; Itoh, H; Kanda, T; Kawabe, H; Kitahama, R; Komatsu, M; Kurokochi, A; Ono, T; Shigaki, S; Tokuyama, H; Urai, H; Wakino, S; Yukioka, H | 1 |
Bao, L; Chen, Z; Ding, G; Guo, M; Guo, W; Liu, F; Zhan, Y; Zhang, M; Zhao, Y; Zheng, N | 1 |
Hamaguchi, T; Horibe, S; Kawauchi, S; Mizuno, S; Rikitake, Y; Sasaki, N; Tanahashi, T | 1 |
Bader, BL; Dahlhoff, C; Daniel, H; Desmarchelier, C; Fürst, RW; Geisel, J; Haag, A; Hummel, B; Obeid, R; Sailer, M; Ulbrich, SE | 1 |
He, J; Hu, B; Huang, M; Kelley, EE; Lu, P; Shi, X; Weidert, ER; Xie, W; Xu, M | 1 |
Berneman, Z; Boeykens, N; De Greef, K; Ponsaerts, P; Van der Linden, A; Ysebaert, D | 1 |
Ables, GP; Caliendo, NS; Malloy, VL; Mattocks, DA; Orentreich, DS; Orentreich, N; Perrone, CE | 1 |
Choi, MK; Han, JM; Kim, HG; Lee, HW; Lee, JS; Park, HJ; Son, CG | 1 |
Baghdasaryan, A; Claudel, T; Das, SK; Halilbasic, E; Hoefler, G; Jha, P; Lass, A; Mueller, M; Trauner, M; Zechner, R; Zimmermann, R | 1 |
Obeid, R | 1 |
Chen, J; Chen, W; Deng, T; Lin, J; Qiu, L; Shi, D; Yang, J; Yang, JY; Ying, M | 1 |
Asahara, T; Asano, T; Chonan, O; Fujishiro, M; Fukushima, T; Iwashita, M; Kamata, H; Kushiyama, A; Matsunaga, Y; Nakatsu, Y; Nishimura, F; Okubo, H; Sakoda, H; Yoshida, Y | 1 |
Cheng, L; Dai, RW; Luo, ZL; Ren, JD; Tang, LJ; Tian, FZ; Wang, T; Xiang, K | 1 |
Fujino, M; Kawai, K; Li, XK; Luo, XY; Nakae, S; Sugiyama, T; Takahara, T; Tsukada, K; Tsuneyama, K; Zhong, L | 1 |
Aibara, D; Gonzalez, FJ; Matsuo, K; Matsusue, K; Takiguchi, S; Yamano, S | 1 |
Chan, CC; Hsieh, YC; Huang, YH; Lee, KC; Lin, HC; Yang, YY | 1 |
Ezaki, T; Itagaki, H; Morikawa, S; Ogawa, K; Shimizu, K | 1 |
de Luka, S; Ethuričić, I; Jorgačević, B; Mladenović, D; Ninković, M; Radosavljević, TS; Sobajić, S; Stanković, MN; Vukicevic, RJ | 1 |
Hatano, E; Koyama, Y; Nakamura, K; Seo, S; Takemoto, K; Tanabe, K; Taura, K; Toriguchi, K; Uemoto, S | 1 |
Rezazadeh, A; Yazdanparast, R | 1 |
Canet, MJ; Cherrington, NJ; Clarke, JD; Dzierlenga, AL; Hardwick, RN; Lake, AD | 1 |
Burrington, CM; Chowdhry, S; Davenport, SK; Greene, MW; Horsman, MJ; Johnson, AK; Lynch, DT; Sparks, JD; Tirrell, PC; Zhang, J | 1 |
Aleksić, V; Duričić, I; Ješić-Vukićević, R; Jorgačević, B; Mladenović, DR; Radosavljević, TS; Šobajić, SS; Stanković, MN; Timić, J; Vučević, DB | 1 |
Claudel, T; Hoefler, G; Jha, P; Knopf, A; Koefeler, H; Lackner, C; Mueller, M; Trauner, M | 1 |
Albano, E; Bena, S; Bozzola, C; Bugianesi, E; Jindal, A; Kusters, D; Locatelli, I; McArthur, S; Parola, M; Paternostro, C; Perretti, M; Reutelingsperger, C; Sutti, S; Vacchiano, M | 1 |
Baud, V; Billot, K; Collin de l'Hortet, A; Fauveau, V; Gilgenkrantz, H; Guidotti, JE; Helmy, N; Prip-Buus, C; Vons, C; Zerrad-Saadi, A; Ziol, M | 1 |
Chen, S; Gu, J; Ji, L; Liu, X; Peng, X; Shen, X; Wu, W; Xue, R; Zhang, S | 1 |
Berk, M; Dixon, L; Feldstein, AE; Inzaugarat, ME; Papouchado, BG; Povero, D; Thapaliya, S; Wree, A | 1 |
Choi, YK; Jang, BK; Jung, GS; Jung, YA; Kim, HS; Kim, JG; Kim, MK; Lee, IK; Park, KG; Seo, HY | 1 |
Azuma, T; Hoshi, N; Kawano, Y; Minami, A; Nishiumi, S; Terashima, Y; Yoshida, M | 1 |
Cho, EJ; Jang, ES; Kim, CY; Kim, YJ; Kwak, MS; Lee, HS; Lee, JH; Yoon, JH; Yu, SJ | 1 |
Kim, YS; Koo, BA; Lee, HS; Ryu, JE; Son, WC | 1 |
Toohey, JI | 1 |
Guo, H; Jiang, X; Ling, W; Shen, T; Sun, X; Tang, X; Xia, M | 1 |
Chang, CJ; Liou, SS; Liu, IM; Tzeng, TF | 1 |
Kobayashi, Y; Nohara, K; Okamura, K; Sano, T; Takumi, S; Yanagisawa, H | 1 |
Akimoto, T; Alam, MM; Goto, M; Haseba, T; Kitamura, H; Motohashi, H; Ota, N; Shimizu, A; Takano-Yamamoto, T; Yamamoto, M | 1 |
Aube, C; Bazeries, P; Boursier, J; Chaigneau, J; Ducluzeau, PH; Fizanne, L; Flamment, M; Leiber, LM; Michalak, S; Moal, V; Roullier, V; Roux, J | 1 |
Bala, S; Catalano, D; Csak, T; Iracheta-Vellve, A; Kodys, K; Lippai, D; Szabo, G | 1 |
Aldámiz-Echevarría, L; Andrade, F; Aspichueta, P; Barbier-Torres, L; Beraza, N; Falcon-Perez, JM; Fernandez, ML; Fernández-Ramos, D; Fernandez-Tussy, P; García-Monzón, C; García-Rodríguez, JL; Juan, VG; Lage-Medina, S; Lopitz-Otsoa, F; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Martínez-Uña, M; Mato, JM; Varela-Rey, M; Wagner, C; Woodhoo, A; Zubiete-Franco, I | 1 |
Bertone, V; Boncompagni, E; Ferrigno, A; Freitas, I; Gruppi, C; Milanesi, G; Tarantola, E; Tira, ME; Vaccarone, R; Vairetti, M | 1 |
Chmiel, KJ; Halsted, CH; Kharbanda, KK; Kim, K; Medici, V; Olson, K; Rutledge, JC; Shibata, NM; Su, RJ; Syed, R; Yokoyama, A | 1 |
Ai, D; He, J; Jiang, C; Liu, W; Liu, Y; Peng, L; Wang, C; Yao, L; Zhang, X; Zhu, Y | 1 |
Harimoto, N; Ikegami, T; Itoh, S; Kimura, K; Maehara, Y; Okano, S; Shirabe, K; Takeishi, K; Uchiyama, H; Yoshizumi, T | 1 |
Berardo, C; Croce, AC; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Rizzo, V; Vairetti, M | 1 |
Cai, D; Hu, Y; Idriss, AA; Jia, Y; Liu, J; Omer, NA; Sun, Q; Zhao, R | 1 |
Hennig, B; Hoffman, JB; Perkins, JT; Petriello, MC; Stromberg, AJ; Wahlang, B | 1 |
Harada, S; Kim, KI; Kim, SK; Kim, SR; Miyagi, K; Morimoto, Y; Nakamoto, K; Obata, T; Tokuyama, S | 1 |
Bian, Y; Fang, M; Li, L; Shao, J; Xu, H; Xu, Y; Yang, L | 1 |
Bell-Anderson, KS; Farrell, GC; Larter, CZ; Williams, J; Yeh, MM | 1 |
Akahori, H; Ando, H; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa-Nagata, N; Misu, H; Nabemoto, S; Nakanuma, Y; Ota, T; Takamura, T; Uno, M; Zen, Y | 1 |
Baéza, E; Bauchart, D; Davail, S; Durand, D; Gruffat, D; Saez, G | 2 |
Akao, M; Hibi, T; Irie, R; Miyashita, K; Mizutani, A; Noguchi, M; Ohkura, T; Oike, Y; Sumimoto, H; Suzuki, T; Tabata, M; Taguchi, T; Takayanagi, A; Tamiya, G; Teratani, T; Tomita, K; Yokoyama, H | 1 |
Larter, CZ; Yeh, MM | 1 |
Dolganiuc, A; Ellis, M; Kodys, K; Mandrekar, P; Petrasek, J; Szabo, G; Velayudham, A | 1 |
Berk, M; Feldstein, AE; Li, ZZ; McIntyre, TM | 1 |
Aeed, H; Avni, Y; Ilan, Y; Shahmurov, M; Shalev, T; Shirin, H; Sorin, V; Stavinski, S | 1 |
Abarca-Quinones, J; Brichard, S; Da Silva Morais, A; Guigas, B; Hue, L; Lebrun, V; Leclercq, IA; Viollet, B | 1 |
Blair, IA; Gong, W; Huang, Y; Lorent, K; Mañoral-Mobias, R; Matthews, RP; Murray, IV; Pack, M | 1 |
Brooling, J; dela Pena, A; Farrell, GC; Francisco, R; Hou, JY; Larter, CZ; Osvath, SR; Sedger, LM; Teoh, N; Williams, J; Yeh, MM; Zhang, RH | 1 |
Beysen, C; Grenert, JP; Maher, JJ; Ng, RK; Ogata, H; Pickens, MK; Turner, SM; Yan, JS | 1 |
Kalhan, SC | 1 |
Kanayama, M; Kawai, K; Kudo, H; Mann, DA; Morita, S; Nakayama, Y; Oya, T; Sasahara, M; Sugiyama, T; Takahara, T; Yata, Y | 1 |
Bagnyukova, TV; Beland, FA; Latendresse, JR; Melnyk, S; Montgomery, B; Pogribny, IP; Ross, SA; Rusyn, I; Tryndyak, VP | 1 |
Harnish, DC; Liu, Q; Wang, J; Zhang, S | 1 |
Akin, H; Atug, O; Avsar, E; Celikel, C; Eren, F; Imeryuz, N; Ozdogan, O; Ozguner, F; Tahan, G; Tahan, V; Tarcin, O; Tozun, N; Uzun, H | 1 |
Miyazaki, H; Takitani, K; Tamai, H; Yoden, A | 1 |
Catalano, D; Dolganiuc, A; Kodys, K; Mandrekar, P; Petrasek, J; Szabo, G; Velayudham, A | 1 |
Abdelmalek, M; Choi, SS; Conde-Vancells, J; Diehl, AM; Fearing, CM; Guy, CD; Jung, Y; Karaca, GF; Omenetti, A; Pereira, TA; Syn, WK; Teaberry, V; Wang, J; Witek, RP; Yang, L | 1 |
Amini, R; Molaei, M; Nosrati, N; Yazdanparast, R | 1 |
Agboola, KM; Charlton, P; Choi, SS; Diehl, AM; Guy, CD; Jung, Y; Karaca, FG; Omenetti, A; Pereira, TA; Pollard, J; Stone, WC; Syn, WK; Teaberry, V; Witek, RP | 1 |
Elias, MS; Green, RM; Henkel, AS | 1 |
Ahsan, MK; Hoshino, Y; Masutani, H; Nakamura, H; Oka, S; Okuyama, H; Yodoi, J | 1 |
Chan, HL; Chu, ES; Farrell, GC; Sung, JJ; Wang, R; Wang, S; Wong, VW; Wu, CW; Yu, J | 1 |
Arena, U; Caligiuri, A; Delogu, W; Galastri, S; Laffi, G; Marra, F; Milani, S; Novo, E; Parola, M; Pinzani, M; Provenzano, A; Vizzutti, F; Zamara, E | 1 |
Ashford, ML; Chowdhry, S; Dillon, JF; Dinkova-Kostova, AT; Hayes, JD; Meakin, PJ; Nazmy, MH; Tsujita, T; Walsh, SV | 1 |
Hyodo, I; Ishige, K; Ishii, T; Nakahara, A; Okada, K; Shoda, J; Sugimoto, H; Taguchi, K; Ueda, T; Warabi, E; Yamamoto, M; Yanagawa, T | 1 |
Carpentier, S; Danjoux, M; Garcia, V; Levade, T; Mas, E; Ségui, B | 2 |
Kawada, N; Mu, YP; Ogawa, T | 1 |
Guo, GL; Luyendyk, JP; Sullivan, BP; Wang, R | 1 |
Apte, U; Behari, J; Cieply, B; Evans, R; Hauth, B; Krauland, L; Monga, SP; Otruba, W; Wu, T; Yeh, TH | 1 |
Du, ZY; El-Mowafi, A; Espe, M; Liaset, B; Rathore, RM | 1 |
Gentile, CL; Nivala, AM; Pagliassotti, MJ; Pfaffenbach, KT; Wang, D; Wei, Y | 1 |
Chen, XR; Kwada, N; Mu, YP; Ogawa, T; Xi, XH | 1 |
Chang, SI; Chen, TC; Hsiao, IT; Lin, KJ; Yeh, TS; Yen, TC | 1 |
Chen, XR; Mu, YP; Xi, XH | 1 |
Klaassen, CD; Tanaka, Y; Yeager, RL; Zhang, YK | 1 |
Fujii, H; Itoh, Y; Niimi, T; Nishimura, T; Okanoue, T; Yamaguchi, K; Yokomizo, C; Yoshikawa, T | 1 |
Cheng, AS; Chu, ES; Lam, CN; Lee, CW; Sung, JJ; Wong, VW; Wu, CW; Yu, J | 1 |
Caballeria, J; Caballero, F; Elena, M; Fernández, A; Fernández-Checa, JC; Fucho, R; García-Ruiz, C; Martínez, L; Matías, N; Morales, A | 1 |
Galle, PR; Schattenberg, JM | 1 |
Adegboyega, P; Allman, M; Brady, K; Gaskin, L; Pang, J; Pruitt, K; Rivera, CA | 1 |
Adams, DH; Choi, SS; Diehl, AM; Fearing, CM; Guy, CD; Jung, Y; Karaca, GF; Omenetti, A; Oo, YH; Pereira, FE; Pereira, TA; Syn, WK; Teaberry, V; Witek, RP | 1 |
Grenert, JP; Maher, JJ; Ogata, H; Pickens, MK; Soon, RK | 1 |
Bammler, TK; Beyer, RP; Botta, D; Campbell, JS; Fausto, N; Haque, JA; Kavanagh, TJ; McMahan, RS; Montine, TJ; Shimizu-Albergine, M; Wilson, AM; Yeh, MM | 1 |
Anstee, QM; Charlton, P; Concas, D; Goldin, RD; Kudo, H; Levene, A; Pollard, J; Thomas, HC; Thursz, MR | 1 |
Grenert, JP; Maher, JJ; Soon, RK; Yan, JS | 1 |
Guo, GL; Kassel, KM; Luyendyk, JP; Tawfik, O | 1 |
Harada, T; Imada, K; Kajikawa, S; Kawashima, A; Mizuguchi, K; Shimizu, Y; Takeuchi, T | 1 |
Fu, MM; Sun, R; Tian, ZG; Wei, HM | 1 |
Abdelmalek, MF; Adams, DH; Agboola, KM; Bhattacharya, SD; Chen, Y; Choi, SS; Diehl, AM; Guy, CD; Jung, Y; Karaca, GF; Kuo, PC; Liaskou, E; Malladi, P; Mi, Z; Michelotti, GA; Moylan, C; Omenetti, A; Oo, YH; Pereira, TA; Syn, WK; Teaberry, V; Whitington, PF; Zdanowicz, M | 1 |
Han, F; Kong, LB; Nan, YM; Wang, RQ; Wu, WJ; Yu, J; Zhao, SX | 1 |
Fu, N; Han, F; Kong, L; Nan, Y; Wang, R; Wu, WJ; Yu, J; Zhao, S | 1 |
CHAIKOFF, IL; ENTENMAN, C; MONTGOMERY, ML | 1 |
Aghazadeh, S; Amini, R; Ghaffari, SH; Yazdanparast, R | 1 |
Andrew, R; Aucott, RL; Iredale, JP; Livingstone, DE; Macfarlane, DP; Morton, NM; Nyirenda, MJ; Walker, BR; Zou, X | 1 |
Horiguchi, N; Kakizaki, S; Mori, M; Takizawa, D; Tojima, H; Yamazaki, Y | 1 |
Catalano, D; Csak, T; Dolganiuc, A; Hritz, I; Kurt-Jones, E; Levin, I; Lippai, D; Mandrekar, P; Petrasek, J; Szabo, G; Velayudham, A | 1 |
Heger, M; Kloek, JJ; Marsman, HA; Nederveen, AJ; Nienhuis, SL; Stoker, J; Ten Kate, FJ; van Gulik, TM; van Werven, JR | 1 |
Lu, SC; Mato, JM | 1 |
Bachmair, EM; Boekschoten, MV; Brennan, L; Coort, SL; Daniel, H; Evelo, C; Gibney, MJ; Keijer, J; Kleemann, R; McLoughlin, GA; Muller, M; Roos, Bd; Rubio-Aliaga, I; Sailer, M; van Erk, M; van Schothorst, EM | 1 |
Han, F; Kong, L; Kong, LB; Nan, YM; Wang, RQ; Wu, WJ; Yu, J; Zhao, SX | 1 |
Fujii, H; Itoh, Y; Niimi, T; Nishimura, T; Okanoue, T; Umemura, A; Yamaguchi, K; Yokomizo, C; Yoshikawa, T | 1 |
Bala, S; Csak, T; Dolganiuc, A; Kodys, K; Lippai, D; Nath, B; Petrasek, J; Szabo, G | 1 |
Bennett, C; Dasarathy, S; Duenas, C; Edmison, J; Gruca, LL; Kalhan, SC; Lopez, R; Marczewski, S | 1 |
Csak, T; Dolganiuc, A; Ganz, M; Kodys, K; Pespisa, J; Szabo, G | 1 |
Clarke, CN; Edwards, MJ; Lentsch, AB; Schuster, R; Tevar, AD; Wang, J | 1 |
Elias, M; Gardikiotes, K; Gottstein, J; Green, RM; Rinella, ME; Siddiqui, MS | 1 |
Banasch, M; Ellrichmann, M; Goetze, O; Schmidt, WE; Tannapfel, A | 1 |
Heger, M; Kloek, JJ; Marsman, HA; Nienhuis, SL; ten Kate, FJ; van Gulik, TM | 1 |
Dilger, RN; Garrow, TA; Gupta, S; Kruger, WD; Li, L; Strakova, J; Tryon, K | 1 |
Katsuya, T; Kiomy Osako, M; Koriyama, H; Kyutoku, M; Minobe, N; Miyake, T; Morishita, R; Moritani, T; Nakagami, F; Nakagami, H; Shimamura, M; Shimizu, H; Shimosato, T | 1 |
Miyahara, T; Miyata, Y; Moriyasu, F | 1 |
Cho, MS; Jang, JE; Jeon, BH; Koh, EH; Lee, KU; Leem, J; Park, HS; Park, IS; Woo, SH | 1 |
Bonora-Centelles, A; Castell, JV; José Gómez-Lechón, M; López, S; Negro, A; Pareja, E; Teresa Donato, M; Tolosa, L | 1 |
Cho, WK; Choi, HS; Hahm, JS; Jang, KS; Jeon, HJ; Jun, DW; Jun, JH; Kim, HJ; Kwon, HJ; Lee, HL; Lee, KN; Lee, MH; Lee, OY; Yoon, BC | 1 |
Brückner, S; Christ, B; Pelz, S; Stock, P | 1 |
Canet, MJ; Cherrington, NJ; Fisher, CD; Hardwick, RN; Street, SM | 1 |
Bauer, S; Buechler, C; Eisinger, K; Hellerbrand, C; Higuchi, A; Schäffler, A; Walsh, K; Walter, R; Wanninger, J; Weiss, TS | 1 |
Kim, HS; Kim, JG; Kim, MK; Lee, IK; Lee, KU; Min, AK; Park, KG; Seo, HY | 1 |
Bucchieri, F; Bugianesi, E; Galvano, F; Li Volti, G; Mangiameli, A; Marino Gammazza, A; Marino, A; Parola, M; Paternostro, C; Salamone, F; Tibullo, D | 1 |
Gonzalez, FJ; Krausz, KW; Matsubara, T; Patterson, AD; Tanaka, N | 1 |
Camporez, JP; Eisenbarth, SC; Elinav, E; Flavell, RA; Gordon, JI; Hao, L; Henao-Mejia, J; Hoffman, HM; Jin, C; Jurczak, MJ; Kau, AL; Mehal, WZ; Shulman, GI; Strowig, T; Thaiss, CA | 1 |
Cha, BS; Chae, MK; Kang, ES; Lee, BW; Lee, HC; Park, SG; Song, SO | 1 |
Catalán, V; Frühbeck, G; Gómez-Ambrosi, J; Oliver, J; Roca, P; Rodríguez, A; Rotellar, F; Salvador, J; Silva, C; Valentí, V; Valle, A | 1 |
Harada, N; Hashimoto, E; Horie, M; Ishii, T; Itoh, K; Okada, K; Shoda, J; Sugimoto, H; Taguchi, K; Tokushige, K; Ueda, T; Utsunomiya, H; Warabi, E; Yamamoto, M | 1 |
Molaei, M; Rezazadeh, A; Yazdanparast, R | 1 |
Berk, M; Dixon, LJ; Feldstein, AE; Papouchado, BG; Thapaliya, S | 1 |
Kwada, N; Mu, YP; Ogawa, T | 1 |
Anderson, KA; Dewey, AM; Green, RM; Henkel, AS; Olivares, S | 1 |
Barbagallo, I; Cappello, F; Galvano, F; Li Volti, G; Mangiameli, A; Salamone, F | 1 |
Ebinuma, H; Hatsuse, K; Hibi, T; Hokari, R; Irie, R; Kanai, T; Kurihara, C; Mataki, N; Minamino, T; Miura, S; Nishiyama, K; Okada, Y; Oshikawa, T; Saito, H; Shimamura, K; Shimizu, I; Sugiyama, K; Suzuki, T; Teratani, T; Tomita, K; Yamamoto, J; Yokoyama, H; Yoshida, Y | 1 |
Conde de la Rosa, L; Fernandez, A; Fernandez-Checa, JC; Fucho, R; Garcia-Ruiz, C; Kaplowitz, N; Machida, K; Mansouri, A; Martinez-Chantar, ML; Matias, N; Mato, JM; Murphy, MP; Tsukamoto, H; von Montfort, C | 1 |
Canet, MJ; Cherrington, NJ; Gandolfi, AJ; Hardwick, RN; Klimecki, WT; Kopplin, MJ; Lake, AD; Scheffer, GL | 1 |
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Tsai, TH; Yang, YY | 1 |
Battle, M; Doddapattar, P; Hoefler, G; Kratky, D; Levak-Frank, S; Obrowsky, S; Patankar, JV | 1 |
Barakat, HA; Hamza, AH | 1 |
González-Gallego, J; Marcolin, E; Marroni, N; San-Miguel, B; Tieppo, J; Tuñón, MJ; Vallejo, D | 1 |
Bigaud, E; Corrales, FJ; He, B; O'Malley, BW; Prieto, J; Sánchez-Quiles, V; Santamaría, E; Segura, V | 1 |
Hahn, YS; Landes, SG; Nguyen, V; Novobrantseva, TI; Tosello-Trampont, AC | 1 |
Davaatseren, M; Hur, HJ; Hwang, JT; Kim, HJ; Kim, MJ; Kim, MS; Kwon, DY; Park, JH; Sung, MJ; Yang, HJ | 1 |
Carmeliet, P; Casteleyn, C; Colle, I; Coulon, S; Geerts, A; Heindryckx, F; Jonckx, B; Leclercq, I; Legry, V; Libbrecht, L; Olievier, K; Stassen, JM; Van Steenkiste, C; Van Vlierberghe, H | 1 |
Hada, N; Ito, T; Katsume, A; Matsumoto, M; Sakamaki, Y; Shiga, T; Sudoh, M; Tanaka, C; Uno, A | 1 |
Bassani, VL; Borghetti, GS; Forgiarini, LF; Marcolin, E; Marroni, NP; Picada, JN; Rodrigues, G; Tieppo, J | 1 |
Farrell, GC; Hall, P; Ip, E; Kirsch, R; Leclercq, I; Robertson, G | 1 |
SHILS, ME; STEWART, WB | 1 |
VENTURI, VM | 1 |
JANSEN, L | 1 |
BECCARI, E; GARESIO, T | 1 |
MENGHINI, G | 1 |
CORNATZER, WE; SNYDER, F | 1 |
FARBER, E; SIDRANSKY, H | 1 |
BEST, CH; LUCAS, CC; WILGRAM, GF | 1 |
KRIKELIS, J; MARGARONIS, K; TSAMBOULAS, N | 1 |
CORNATZER, WE; SNYDER, F; SYNDER, C | 1 |
METAIS, P; SACREZ, A; SCHIRARDIN, H; WARTER, J | 1 |
METAIS, P; SACREZ, A; WARTER, J; WERYHA, A | 1 |
SRIRAMACHARI, S | 1 |
SKALKA, M | 1 |
JASIK, AD; WILLIAMS, JN | 1 |
HUTTERER, F | 1 |
SOKOLOVSKAIA, IaI | 1 |
FINKELSTEIN, JD; IRREVERRE, F; LASTER, L; MUDD, SH | 1 |
NOMURA, T | 2 |
REVELLI, M | 1 |
KENNEDY, JS; PATRICK, RS | 1 |
FARBER, E; LOMBARDI, B; SHULL, KH; THOMAS, M; VILLA-TREVINO, S | 1 |
SUEYOSHI, Y; TOKUDA, R | 1 |
COOK, CR; LYMAN, RL; THENEN, S | 1 |
Hurlebaus, AJ; Williams, JN | 1 |
CARSON, NA; DENT, CE; FIELD, CM; GAULL, GE | 1 |
KOWALEWSKI, K | 1 |
INOUE, K | 1 |
RADOMSKI, MW; WOOD, JD | 1 |
GEER, BW; VOVIS, GF | 1 |
DE GIOVANNI, R; SHILS, ME; STEWART, WB | 1 |
KAWAKAMI, T; TOKUDA, R | 1 |
Clarkson, V; Hall, Pde L; Jaffer, MA; Kirsch, R; Kirsch, RE; Marais, DA; Shephard, EG; Woodburne, VE | 1 |
Farrell, G; George, J; Leclercq, I; Pera, N; Phung, N; Yun Hou, J | 1 |
Green, RM; Rinella, ME | 1 |
Kashireddy, PR; Rao, MS | 1 |
BENARD, H; GAJDOS, A | 1 |
Green, RM; Malladi, P; Melin-Aldana, H; Sahai, A; Whitington, PF | 1 |
Green, RM; Malladi, P; Melin-Aldana, H; Pan, X; Paul, R; Sahai, A; Whitington, PF | 1 |
Farrell, GC; Ito, Y; McCuskey, MK; McCuskey, RS; Perry, M; Robertson, GR | 1 |
HARTMANN, F; LEUSCHNER, F | 1 |
Green, RM; Koppe, SW; Malladi, P; Sahai, A; Whitington, PF | 1 |
dela Peña, A; Farrell, GC; Horsmans, Y; Leclercq, IA; Sempoux, C | 1 |
Czaja, MJ; Rigoli, RM; Schattenberg, JM; Singh, R; Wang, Y | 1 |
Green, RM; Sundaram, SS; Whitington, PF | 1 |
Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Rogers, DD; Siford, GL; Sorrell, MF; Tuma, DJ | 1 |
Ando, S; Chiyo, T; Han, JY; Hibi, T; Horie, Y; Ishii, H; Kaneko, T; Kato, S; Kitamura, N; Kumagai, N; Makino, S; Mizutani, A; Nagata, H; Ohkura, T; Ohsumi, K; Oike, Y; Saito, H; Shimoda, M; Tamiya, G; Toda, K; Tomita, K; Tomizawa, M | 1 |
Brown, JL; Hirose, R; Jackman, M; Liu, T; Maher, JJ; Niemann, CU; Roberts, JP; Serkova, NJ | 1 |
Dela Peña, A; Farrell, G; Field, J; George, J; Jones, B; Leclercq, I | 1 |
Czaja, MJ; Lefkowitch, JH; Rigoli, RM; Schattenberg, JM; Scherer, PE; Singh, R; Wang, Y | 1 |
Green, RM; Igolnikov, AC | 1 |
Kohli, R; Malladi, P; Pan, X; Paul, R; Sahai, A; Whitington, PF | 1 |
Chen, TS; de Villiers, WJ; Im, HJ; McClain, CJ; Oz, HS | 1 |
Dela Peña, A; Farrell, GC; Hall, P; Hou, JY; Ip, E; Kirsch, R; Leclercq, I; Pera, N; Sesha, J; Yu, J | 1 |
Inada, Y; Kuroda, J; Maruyama, K; Nagasawa, T; Nakano, S; Shibata, N; Takahashi, T; Tamura, T; Yamazaki, Y | 1 |
Banerjee, R; Bauman, Z; Braun, A; Lu, SC; Prudova, A; Vitvitsky, V | 1 |
Clarkson, V; de la M Hall, P; Kirsch, R; Marais, AD; Ryffel, B; Shephard, EG; Verdonk, RC | 1 |
Horiguchi, N; Kakizaki, S; Mori, M; Negishi, M; Sato, K; Sohara, N; Takagi, H; Yamazaki, Y | 1 |
Green, RM; Igolnikov, A; Lammert, F; Rangnekar, AS | 1 |
Hall, Pde L; Kirsch, R; Marais, AD; Sijtsema, HP; Tlali, M | 1 |
dela Peña, A; Farrell, GC; Leclercq, IA; Williams, J | 1 |
Akahori, H; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa, N; Misu, H; Nakanuma, Y; Ota, T; Sakurai, M; Takamura, T; Uno, M; Zen, Y | 1 |
Li, Z; Vance, DE | 1 |
Barve, S; Cave, M; Deaciuc, I; Joshi-Barve, S; McClain, C; Mendez, C; Song, Z | 1 |
Alves, VA; Barbeiro, HV; Caldwell, SH; Carrilho, FJ; de Lima, VM; de Mello, ES; de Oliveira, CP; Sawada, LY; Soriano, FG | 1 |
Chan, HL; Cheung, KF; Chu, ES; Farrell, GC; Hui, AY; Leung, WK; Sung, JJ; Yu, J | 1 |
Akisawa, N; Dong, H; Hirose, A; Iwasaki, S; Li, C; Nozaki, Y; Onishi, S; Ono, M; Saibara, T; Takahashi, M; Wang, J | 1 |
Bessems, M; Doorschodt, BM; Kolkert, JL; van Gulik, TM; van Marle, J; van Vliet, AK; Vetelainen, RL; Vreeling, H | 1 |
Bahcecioglu, IH; Duzgun, S; Gulcu, F; Koca, S; Ozercan, IH; Sahin, K; Ustundag, B | 1 |
Friedman, JE; Janssen, RC; Jiang, H; Maclean, KN; Qadri, I; Rahman, SM; Schroeder-Gloeckler, JM | 1 |
Bhanot, S; Diehl, AM; Huang, J; Li, YX; McCall, S; Monia, BP; Pandey, SK; Yamaguchi, K; Yang, L; Yu, XX | 1 |
Akisawa, N; Hirose, A; Iwasaki, S; Masuda, K; Nozaki, Y; Oben, JA; Onishi, S; Ono, M; Saibara, T; Takahashi, M; Yoshioka, A | 1 |
Kakar, S; Lee, GS; Maher, JJ; Ng, RK; Yan, JS | 1 |
Ikejima, K; Kon, K; Okumura, K; Sato, N; Takei, Y | 1 |
Adegboyega, P; Allman, M; Rivera, CA; Tagalicud, A; van Rooijen, N; Wallace, M | 1 |
Bader, M; Clavien, PA; Dahm, F; Georgiev, P; Jang, JH; Jochum, W; Nocito, A; Renner, EL | 1 |
Aeed, H; Avni, Y; Birkenfeld, S; Bruck, R; Matas, Z; Shahmurov, M; Shirin, H | 1 |
Chen, TS; Neuman, M; Oz, HS | 1 |
Larter, CZ | 1 |
van Gulik, TM; van Vliet, A; Veteläinen, R | 1 |
Augustine, LM; Cherrington, NJ; Fisher, CD; Lickteig, AJ | 1 |
Devaraj, S; Esfandiari, F; French, SW; Halsted, CH; Villanueva, JA; White, ME | 1 |
Bell-Anderson, KS; Brown, S; Cheng, J; dela Pena, A; Farrell, GC; Larter, CZ; Williams, J; Yeh, MM | 1 |
Ichikawa, T; Kakizaki, S; Mori, M; Sato, K; Takagi, H; Takizawa, D; Yamazaki, Y | 1 |
Birkner, E; Birkner, K; Grucka-Mamczar, E; Kasperczyk, A; Kasperczyk, S; Stawiarska-Pieta, B; Zalejska-Fiolka, J | 1 |
Anan, A; Baskin-Bey, ES; Bronk, SF; Gores, GJ; Isomoto, H | 1 |
Belouze, M; Dautresme, M; Duchamp, C; Favier, R; Letexier, D; Mourier, A; Ollivier, I; Piquet, MA; Rey, B; Rigoulet, M; Romestaing, C; Rouleau, V; Servais, S; Sibille, B | 1 |
Damjanov, I; French, S; Gyamfi, MA; Wan, YJ | 1 |
Avsar, E; Celikel, C; Imeryuz, N; Tahan, V; Tozun, N | 1 |
Bahcecioglu, IH; Koca, SS; Ozercan, IH; Poyrazoglu, OK; Sahin, K; Ustundag, B | 1 |
Chan, HL; Chu, ES; Lin, G; Shen, B; Sung, JJ; Wang, S; Wong, VW; Yu, J; Zhou, X | 1 |
Borensztajn, J; Elias, MS; Fu, T; Green, RM; Rinella, ME; Smolak, RR | 1 |
Copple, BL; Gyamfi, M; He, L; Wan, YJ; Wortham, M | 1 |
Aransay, AM; Ariz, U; Calvisi, DF; Capdevila, A; Esteller, M; Fraga, M; Lu, SC; Luka, Z; Martínez, N; Martínez-Chantar, ML; Mato, JM; Matthiesen, R; Rodríguez, J; Varela, M; Vázquez-Chantada, M; Wagner, C; Yang, H | 1 |
Kumagai, N; Morinaga, S; Sugino, H; Takeuchi, O; Toda, K; Tsuchimoto, K; Tsunematsu, S; Watanabe, S | 1 |
Chan, C; Ji, C; Kaplowitz, N; Ookhtens, M; Shinohara, M; Than, TA; Vance, D | 1 |
Ando, H; Ishikura, K; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa-Nagata, N; Misu, H; Nabemoto, S; Nakanuma, Y; Ota, T; Takamura, T; Uno, M; Zen, Y | 1 |
Alexander, NM; Klatskin, G; Scheig, R | 1 |
Cardi, E; Ehrich, WE; Goldblatt, H; György, P; Hirooka, M; Langer, BW | 1 |
Egan, RF; Sidransky, H; Verney, E | 1 |
Cardi, E; György, P; Hirooka, M; Langer, BW; Rose, CS | 1 |
Noda, K; Okita, T | 1 |
Kato, T; Matsuo, T; Seri, K | 1 |
Bowers, JL; Clouse, ME; Endo, M; Hara, J; Iwai, T; Kruskal, JB; Teramoto, K | 1 |
Bowers, JL; Clouse, ME; Khettry, U; Palombo, JD; Teramoto, K | 1 |
Denda, A; Endoh, T; Horiguchi, K; Kobayashi, E; Konishi, Y; Nakae, D; Noguchi, O; Ogasawara, H; Sugimura, M; Tamura, K; Tang, Q; Tsujiuchi, T | 1 |
Baek, Y; Barama, A; Boudjema, K; Jaeck, D; Kitamura, N; Kumada, K; Nagasaki, H; Nakano, H; Suzuki, T; Tatsuno, M; Yamaguchi, M | 1 |
Fujiwara, Y; Kaneshiro, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Matsumoto, F; Nagasaki, H; Nakano, H; Sasaki, J; Takeuchi, S; Yamaguchi, M; Yoshida, K | 1 |
Fujiwara, Y; Kigawa, G; Kitamura, N; Kumada, K; Kuzume, M; Nagasaki, H; Nakano, H; Sasaki, J; Shimura, H; Takeuchi, S; Yamaguchi, M; Yoshida, K | 1 |
Farrell, GC; Weltman, M; Zhang, BH | 1 |
Bertics, SJ; Grummer, RR | 1 |
Bell, DR; Farrell, GC; Field, J; Gonzalez, FJ; Leclercq, IA; Robertson, GR | 1 |
Aoyama, Y; Inaba, T; Yoshida, A | 1 |
Horsmans, Y; Lambotte, L; Picard, C; Saliez, A; Sempoux, C; Starkel, P; Van den Berge, V | 1 |
Aizawa, Y; Negishi, I | 1 |
Knoke, M; Lubs, H; Peters, WH; Zschiesche, M | 1 |
Andreana, A; Galletti, P; Porcelli, M; Ruggiero, G; Zappia, V | 1 |
Roberson, RH; Trujillo, T | 1 |
Leclerc, J | 1 |
Henning, SM; McKee, RW; Swendseid, ME | 1 |
Boyd, JN; Graham, ES; Graham, TC; Sherman, WK; Tennant, BC | 1 |
Hathcock, JN | 1 |
Aoyama, Y; Ashida, K; Yasui, H | 1 |
Newberne, PM; Rogers, AE | 1 |
Bannister, DW; Blair, R; Evans, AJ; Whitehead, CC | 2 |
Carbonneau, R; Demers, JM | 1 |
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
Aoyama, Y; Ashida, K; Nakanishi, M | 1 |
Hosotani, T; Yoshida, A | 1 |
Gilchrist, P; Hemsley, LA; Payne, CG; Pearson, JA | 1 |
Murphy, D; Wolford, JH | 1 |
Aoyama, Y; Ashida, K | 1 |
Dragstedt, LR; Vadhanasindhu, P | 2 |
Hayes, KC; Hegsted, DM; Said, AK | 1 |
Lieber, CS; Rubin, E | 1 |
Farber, E | 1 |
Szabb, L | 1 |
Dunn, MA; Quinn, TC; Terwedow, HA | 1 |
Gasbarrini, G; Labò, G; Miglio, F | 1 |
Noda, K | 1 |
Blum, JC; Leclercq, B; Monachon, G | 1 |
Nagasaka, Y; Osumi, Y; Shimamoto, K | 1 |
Hartroft, WS; Porta, EA; Sugioka, G | 1 |
Applegarth, DA; Cder, RJ; Cockcroft, DM; Hardwick, DF; Ross, PM | 1 |
Derevenco, V; Fekete, T; Frăţilă, I; Gligore, V; Holan, T; Scurtu, A; Tecuceanu, R | 1 |
Mahlum, DD | 1 |
Lombardi, B; Longnecker, DS; Schlunk, FF | 1 |
Barnes, RH; Krook, L; Pond, WG; Reid, IM | 1 |
Bailey, C; Newberne, PM; Rogers, AE; Young, VR | 1 |
Thomas, H | 1 |
Isozaki, M; Sano, M; Yamamoto, A | 1 |
Wheatley, DN | 1 |
Sidransky, H; Verney, E | 1 |
MacDonald, G; Mookerjea, S; Thompson, W | 1 |
Bianchi, FB; Nigro, F; Pisi, E | 1 |
Fallon, HJ; Klatskin, G; Pesch, LA | 1 |
Remy, CN; Wells, IC | 1 |
Chahl, JS; Kratzing, CC | 1 |
DeCarli, LM; Lieber, CS | 1 |
11 review(s) available for methionine and Liver Steatosis
Article | Year |
---|---|
Sulfur-Containing Amino Acids and Lipid Metabolism.
Topics: Amino Acids, Sulfur; Animals; Atherosclerosis; Betaine; Cholesterol; Cysteine; Dietary Proteins; Dietary Supplements; Fatty Liver; Glutathione; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Sulfur; Sulfur Compounds; Taurine | 2020 |
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine | 2013 |
Sulfur amino acids in diet-induced fatty liver: a new perspective based on recent findings.
Topics: Amino Acids, Sulfur; Animals; Fatty Liver; Humans; Methionine; Sulfur | 2014 |
Animal models of NASH: getting both pathology and metabolic context right.
Topics: Animals; Choline Deficiency; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Disease Progression; Fatty Liver; Genetic Predisposition to Disease; Hyperphagia; Intubation, Gastrointestinal; Liver; Methionine; Overnutrition; Phenotype; Reproducibility of Results | 2008 |
Animal models of non-alcoholic steatohepatitis: of mice and man.
Topics: Animals; Choline Deficiency; Dietary Fats; Disease Models, Animal; Fatty Liver; Humans; Liver; Methionine; Mice | 2010 |
The hepatocarcinogenic effect of methionine and choline deficient diets: an adaptation to the Warburg effect?
Topics: Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Humans; Liver Neoplasms; Methionine | 2011 |
BIOCHEMICAL PATHOLOGY OF ACUTE HEPATIC ADENOSINETRIPHOSPHATE DEFICIENCY.
Topics: Adenosine Triphosphate; Ethionine; Fatty Liver; Methionine; Research; Toxicology | 1964 |
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition.
Topics: Betaine; Cytokines; Dietary Supplements; Environmental Exposure; Fatty Liver; Female; Humans; Insulin Resistance; Life Style; Liver; Liver Cirrhosis; Metabolic Syndrome; Methionine; Middle Aged; Mitochondrial Diseases; Oxidative Stress; S-Adenosylmethionine; United States; Vitamin E; Xenobiotics; Zinc | 2007 |
Nutrient and non-nutrient effects on drug metabolism.
Topics: Acetaminophen; Aged; Antioxidants; Biological Transport; Biotransformation; Carbohydrate Metabolism; Drug Interactions; Enzyme Induction; Ethanol; Fatty Liver; Humans; Kidney; Lipid Metabolism; Methionine; Minerals; Mixed Function Oxygenases; Pharmaceutical Preparations; Proteins; Research; Starvation; Vitamins | 1985 |
Alcoholic fatty liver.
Topics: Adult; Alcoholism; Animals; Child; Choline; Diet; Dietary Fats; Dietary Proteins; Drug Synergism; Ethanol; Fatty Liver; Hepatitis; Humans; Lipid Metabolism; Lipoproteins; Liver; Liver Cirrhosis; Methionine; Microsomes; Protein Deficiency; Rats; Triglycerides | 1969 |
Biochemical pathology.
Topics: Adenosine Triphosphate; Basidiomycota; Carbon Tetrachloride Poisoning; Cell Division; Cell Nucleus; Cycloheximide; Dactinomycin; Deficiency Diseases; Drug Antagonism; Ethionine; Fatty Liver; Fructose; Liver; Lymphoid Tissue; Methionine; Mitochondria; Mycotoxins; Nucleic Acids; Oxidative Phosphorylation; Oxygen Consumption; Peptides; Protein Biosynthesis; Ribosomes; Toxins, Biological | 1971 |
1 trial(s) available for methionine and Liver Steatosis
Article | Year |
---|---|
Four-Week Omega-3 Supplementation in Carriers of the Prosteatotic PNPLA3 p.I148M Genetic Variant: An Open-Label Study.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Dietary Supplements; Elasticity Imaging Techniques; Fatty Acids, Omega-3; Fatty Liver; Female; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Isoleucine; Lipase; Loss of Function Mutation; Male; Membrane Proteins; Methionine; Middle Aged; Non-alcoholic Fatty Liver Disease; Polymorphism, Single Nucleotide; Proteostasis; Time Factors; Young Adult | 2019 |
328 other study(ies) available for methionine and Liver Steatosis
Article | Year |
---|---|
Inhibition of chylomicron assembly leads to dissociation of hepatic steatosis from inflammation and fibrosis.
Topics: Animals; Choline Deficiency; Chylomicrons; Diet; Fatty Liver; Female; Fibrosis; Inflammation; Intestines; Male; Methionine; Mice; Mice, Knockout; Mice, Transgenic; Non-alcoholic Fatty Liver Disease | 2021 |
TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis.
Topics: Amino Acids, Sulfur; Animals; Antioxidants; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Coenzyme A; Cysteine; Cystine; Dietary Proteins; Fatty Liver; Glutathione; Homeostasis; Lipids; Liver; Methionine; Methionine Adenosyltransferase; Mice; Oxidation-Reduction | 2022 |
Effect of source and amount of rumen-protected choline on hepatic metabolism during induction of fatty liver in dairy cows.
Topics: Animals; Cattle; Cattle Diseases; Cholesterol; Choline; Diet; Dietary Supplements; Fatty Acids; Fatty Liver; Female; Glucose; Glycogen; Haptoglobins; Inflammation; Lactation; Liver; Methionine; Milk; Pregnancy; RNA, Messenger; Rumen; Triglycerides | 2023 |
Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Choline; Diet; Fatty Acid-Binding Proteins; Fatty Liver; Inflammation; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout | 2020 |
Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice.
Topics: Adenosine; Animals; Carbon; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Flavins; Guanidine; Inflammation; Liver; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Nucleotides; Purinergic P1 Receptor Antagonists; Thymidine | 2020 |
Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH.
Topics: Adenylate Kinase; Animals; Antioxidants; Apoptosis; Cell Proliferation; Ceramides; Choline; Diet; Diglycerides; Energy Metabolism; Fatty Liver; Feeding Behavior; Hematopoietic Stem Cells; Homeostasis; Humans; Lipidomics; Liposomes; Male; Methionine; Mice, Inbred BALB C; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphorylation; Protein Subunits; Signal Transduction | 2020 |
Automated thermal imaging for the detection of fatty liver disease.
Topics: Algorithms; Animals; Automation; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Female; Humans; Image Processing, Computer-Assisted; Liver; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Thermography; Ultrasonography | 2020 |
A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid-defined, high-fat diet.
Topics: Amino Acids; Animal Feed; Animals; Apoptosis; Body Weight; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Profiling; Humans; Inflammation; Insulin-Like Growth Factor I; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Organ Size; Phosphorylation; RNA; Soybean Oil; Sulfotransferases; Trans Fatty Acids | 2020 |
Honokiol Alleviates Methionine-Choline Deficient Diet-Induced Hepatic Steatosis and Oxidative Stress in C57BL/6 Mice by Regulating CFLAR-JNK Pathway.
Topics: Animals; Biphenyl Compounds; CASP8 and FADD-Like Apoptosis Regulating Protein; Fatty Liver; Food, Formulated; Lignans; Liver; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Methionine; Mice; Oxidative Stress | 2020 |
Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet.
Topics: Alkaline Phosphatase; Alleles; Animals; Choline; Choline Deficiency; Diet; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Fatty Liver; Methionine; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; PPAR alpha; Proto-Oncogene Proteins c-akt; Signal Transduction | 2020 |
Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis.
Topics: Animals; Choline; Choline Deficiency; Cytokines; Diet; Fatty Liver; Hep G2 Cells; Humans; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Prolyl Oligopeptidases; Signal Transduction | 2021 |
Clusters of Ultrasound Scattering Parameters for the Classification of Steatotic and Normal Livers.
Topics: Animals; Disease Models, Animal; Fatty Liver; Liver; Methionine; Rats; Ultrasonography | 2021 |
Long-term cold storage preservation does not affect fatty livers from rats fed with a methionine and choline deficient diet.
Topics: Animals; Choline; Choline Deficiency; Diet; Fatty Liver; Liver; Male; Methionine; Rats; Rats, Wistar; Tissue Preservation | 2021 |
Pigment Epithelium-Derived Factor (PEDF) Prevents Hepatic Fat Storage, Inflammation, and Fibrosis in Dietary Steatohepatitis of Mice.
Topics: Adenoviridae; Adipose Tissue; Alanine Transaminase; Animals; Choline Deficiency; Collagen Type I; Collagen Type III; Diet; Disease Models, Animal; Down-Regulation; Eye Proteins; Fatty Liver; Injections, Intramuscular; Interleukin-1beta; Interleukin-6; Kupffer Cells; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nerve Growth Factors; Oxidative Stress; PPAR gamma; Protease Inhibitors; RNA, Messenger; Serpins; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis.
Topics: Animal Feed; Animals; Choline; Diet; Fatty Liver; Gene Expression Regulation; Lipids; Liver; Methionine; Mice; Mice, Knockout; Phospholipid Transfer Proteins; Thiolester Hydrolases | 2017 |
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway.
Topics: Activating Transcription Factor 4; AMP-Activated Protein Kinases; Animals; Autophagy; Carbon Monoxide; Choline Deficiency; Disease Models, Animal; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Fatty Liver; Gene Expression Regulation; Hepatocytes; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Nuclear Proteins; Organometallic Compounds; Peroxidases; Primary Cell Culture; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction | 2017 |
CD18 deficiency improves liver injury in the MCD model of steatohepatitis.
Topics: Adipose Tissue; Animals; CD18 Antigens; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Hepatocytes; Immunity, Innate; Inflammation; Leukocytes; Lipase; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mutation; Oxygen; Peroxidase; Triglycerides | 2017 |
Effects of betaine supplementation on nitric oxide metabolism, atherosclerotic parameters, and fatty liver in guinea pigs fed a high cholesterol plus methionine diet.
Topics: Animals; Arginine; Atherosclerosis; Betaine; Cholesterol; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Fatty Liver; Guinea Pigs; Hyperlipidemias; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methionine; Nitric Oxide; Tyrosine | 2018 |
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring.
Topics: Animals; Animals, Newborn; Diet; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Female; Folic Acid; Gene Expression; Lipid Metabolism; Liver; Male; Methionine; Micronutrients; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin B 12; Vitamin B 6; Zebrafish; Zebrafish Proteins | 2018 |
NNMT activation can contribute to the development of fatty liver disease by modulating the NAD
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fatty Liver; Lipoproteins, VLDL; Liver; Liver Cirrhosis; Methionine; Mice, Inbred C57BL; Mice, Transgenic; NAD; Niacinamide; Nicotinamide N-Methyltransferase | 2018 |
Wuzhi capsule (Schisandra Sphenanthera extract) attenuates liver steatosis and inflammation during non-alcoholic fatty liver disease development.
Topics: Animals; Choline Deficiency; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fatty Liver; Inflammation; Inflammation Mediators; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Schisandra | 2019 |
Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet.
Topics: Alginates; Animals; Choline Deficiency; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fatty Liver; Intestine, Small; Male; Methionine; Mice; Mice, Inbred C57BL; RNA, Messenger; Tumor Necrosis Factor-alpha | 2019 |
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.
Topics: Amino Acids; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Cell Line, Tumor; Cystathionine beta-Synthase; Diet, High-Fat; Fatty Liver; Gene Expression Regulation, Enzymologic; Homeostasis; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; PPAR alpha; Rats; Sequence Analysis, DNA | 2013 |
Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3.
Topics: Acetylation; Animals; Choline Deficiency; Fatty Liver; Food, Formulated; Gene Expression; Lipid Peroxidation; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Sirtuin 3; Superoxide Dismutase | 2013 |
Injury-dependent retention of intraportally administered mesenchymal stromal cells following partial hepatectomy of steatotic liver does not lead to improved liver recovery.
Topics: Analysis of Variance; Animals; Biomarkers; Body Weight; Choline Deficiency; Cholinesterases; DNA Primers; Fatty Liver; Female; Flow Cytometry; Hepatectomy; Immunophenotyping; Liver Regeneration; Luminescent Measurements; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methionine; Organ Size; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2013 |
Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.
Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Blood Glucose; Diet; Disease Progression; Fatty Acids; Fatty Liver; Gene Expression Regulation; Homeostasis; Inflammation; Insulin; Leptin; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Methionine; Mice; Mice, Obese; Obesity; Oxidation-Reduction; Severity of Illness Index; Triglycerides | 2013 |
Chunggan extract (CGX), methionine-and choline-deficient (MCD) diet-induced hepatosteatosis and oxidative stress in C57BL/6 mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Catalase; Cholesterol; Choline Deficiency; Diet; Drugs, Chinese Herbal; Fatty Liver; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Triglycerides | 2013 |
Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Topics: Animals; Choline Deficiency; Disease Models, Animal; Endotoxemia; Fatty Liver; Female; Lipase; Lipopolysaccharides; Liver; Male; Methionine; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; PPAR alpha; Signal Transduction | 2014 |
Aldose reductase is involved in the development of murine diet-induced nonalcoholic steatohepatitis.
Topics: Aldehyde Reductase; Animals; Blotting, Western; Choline; Diet; Fatty Liver; Female; Interleukin-6; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2013 |
Lactobacillus casei strain Shirota protects against nonalcoholic steatohepatitis development in a rodent model.
Topics: Animals; Bifidobacterium; Choline Deficiency; Disease Models, Animal; Fatty Liver; Gastrointestinal Tract; Gene Expression Profiling; Inflammation; Lacticaseibacillus casei; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C57BL; Microbiota; Non-alcoholic Fatty Liver Disease | 2013 |
Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats.
Topics: Animals; Choline Deficiency; Cytochrome P-450 CYP2E1; Disease Models, Animal; Disease Progression; Fatty Liver; Heme Oxygenase-1; Hydrogen Sulfide; Inflammation; Interleukin-6; Liver; Male; Methionine; Mitochondria, Liver; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2014 |
IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.
Topics: Animals; Cell Line; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Profiling; Hepatic Stellate Cells; Inflammation; Interferon-gamma; Kupffer Cells; Liver; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2013 |
Expression of hepatic fat-specific protein 27 depends on the specific etiology of fatty liver.
Topics: Animals; Choline Deficiency; Diabetes Mellitus; Diet; Diet, High-Fat; Fatty Liver; Female; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; PPAR gamma; Proteins; RNA, Messenger | 2013 |
Aliskiren attenuates steatohepatitis and increases turnover of hepatic fat in mice fed with a methionine and choline deficient diet.
Topics: Amides; Angiotensin II; Animals; Blotting, Western; Choline; Diet; Fatty Liver; Fumarates; Immunoenzyme Techniques; Inflammation; Insulin; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Oxidative Stress; Real-Time Polymerase Chain Reaction; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Triglycerides | 2013 |
Morphological and functional characterization of non-alcoholic fatty liver disease induced by a methionine-choline-deficient diet in C57BL/6 mice.
Topics: Alanine Transaminase; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aspartate Aminotransferases; Biomarkers; Cell Proliferation; Chemokine CCL2; Choline Deficiency; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Kupffer Cells; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Proliferating Cell Nuclear Antigen; RNA, Messenger; Time Factors | 2013 |
The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD.
Topics: Animals; Choline; Diet; Fatty Acids, Nonesterified; Fatty Liver; Humans; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Thioctic Acid | 2014 |
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.
Topics: Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Choline Deficiency; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice, Inbred C57BL; Middle Aged; Molecular Targeted Therapy | 2014 |
Prevention of nonalcoholic steatohepatitis in rats by two manganese-salen complexes.
Topics: Animals; Antioxidants; Ascorbic Acid; Chelating Agents; Choline; Diet; Ethylenediamines; Fatty Liver; Inflammation; Liver; Male; Manganese Compounds; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats | 2014 |
Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models.
Topics: Animals; Choline Deficiency; Diabetes Mellitus, Experimental; Diet, Atherogenic; Disease Models, Animal; Fatty Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity; Organic Anion Transporters; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2014 |
Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis.
Topics: Animals; Apoptosis; Biomarkers; Cells, Cultured; Choline Deficiency; Diet; Endoplasmic Reticulum Stress; Enzyme Activation; Fatty Liver; Female; Gene Expression; Hepatocytes; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Primary Cell Culture; Protein Kinase C-delta | 2014 |
Time-dependent changes and association between liver free fatty acids, serum lipid profile and histological features in mice model of nonalcoholic fatty liver disease.
Topics: Animals; Choline; Diet; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Lipids; Liver; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Risk Factors; Time Factors | 2014 |
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
Topics: Adipogenesis; Adipose Tissue; Animals; Choline; Disease Models, Animal; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Fibroblast Growth Factors; Inflammation; Lipase; Lipid Metabolism; Lipolysis; Liver; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction | 2014 |
Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice.
Topics: Animals; Annexin A1; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity | 2014 |
GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency.
Topics: Animals; Blotting, Western; Cell Proliferation; Choline; Diet; Down-Regulation; ErbB Receptors; Fatty Liver; Hepatectomy; Hepatocytes; Human Growth Hormone; Humans; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Triglycerides | 2014 |
Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis.
Topics: Animals; Bile Acids and Salts; Cholestasis, Intrahepatic; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear | 2014 |
Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet-induced NASH model.
Topics: Animals; Antigens, Ly; Apoptosis; Caspase 3; Choline; Collagen; Dose-Response Relationship, Drug; Fatty Liver; Gene Expression Regulation; Hepatic Stellate Cells; Hepatocytes; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Receptors, CCR2 | 2014 |
Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis.
Topics: Animals; Biomarkers; Blotting, Western; Choline Deficiency; Diet; Dipeptidyl-Peptidase IV Inhibitors; Endoplasmic Reticulum Stress; Fatty Liver; Immunoenzyme Techniques; Inflammation; Lipid Peroxidation; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Pyrazines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sitagliptin Phosphate; Triazoles; Triglycerides | 2014 |
Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis.
Topics: Animals; Choline; Diet; Fatty Liver; Liver; Liver Cirrhosis; Male; Metabolome; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Taurine | 2014 |
Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet.
Topics: Animal Feed; Animals; Apoptosis; Biomarkers; Choline Deficiency; Disease Progression; Drug Administration Schedule; Endoplasmic Reticulum Stress; Fatty Liver; Gastrointestinal Agents; Immunoblotting; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Taurochenodeoxycholic Acid | 2014 |
Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice.
Topics: Animals; Choline; Diet; Fatty Liver; Hepatic Stellate Cells; Humans; Hydrogen Peroxide; Male; Methionine; Mice; Mice, Inbred C57BL; Plant Extracts; Salvia miltiorrhiza | 2014 |
Purified anthocyanins from bilberry and black currant attenuate hepatic mitochondrial dysfunction and steatohepatitis in mice with methionine and choline deficiency.
Topics: AMP-Activated Protein Kinases; Animals; Anthocyanins; Choline Deficiency; Fatty Liver; Humans; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Plant Extracts; Ribes; Transcription Factors; Vaccinium myrtillus | 2015 |
6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism.
Topics: Animals; Catechols; Chemokine CCL2; Choline Deficiency; Disease Models, Animal; Fatty Alcohols; Fatty Liver; Inflammation; Interleukin-6; Lipid Metabolism; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Plant Extracts; Tumor Necrosis Factor-alpha | 2015 |
The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways.
Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Choline Deficiency; Cytosine; Deoxyguanosine; DNA Methylation; Fatty Liver; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Mice, Inbred C57BL; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.
Topics: Alcohol Dehydrogenase; Animals; Choline Deficiency; Diet; Disease Progression; Fatty Liver; Glutathione; Lipid Metabolism; Liver; Methionine; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease | 2015 |
MRI versus histological methods for time course monitoring of steatosis amount in a murine model of NAFLD.
Topics: Adipose Tissue; Animals; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Humans; Image Interpretation, Computer-Assisted; Liver; Magnetic Resonance Imaging; Methionine; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Statistics as Topic; Triglycerides | 2015 |
MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis.
Topics: Animals; CCAAT-Enhancer-Binding Protein-beta; Cell Nucleus; Choline; Diet; Disease Models, Animal; Fatty Liver; Female; Gene Expression Regulation; Inflammation; Lipid Metabolism; Lipopolysaccharides; Liver; Liver Cirrhosis; Methionine; Mice, Inbred C57BL; MicroRNAs; Protein Binding; Smad3 Protein; Tumor Necrosis Factor-alpha; Vimentin | 2015 |
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Topics: Animals; Autophagy; Cell Culture Techniques; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Methionine; Methylation; Mice; Protein Phosphatase 2; S-Adenosylmethionine | 2016 |
In Situ Evaluation of Oxidative Stress in Rat Fatty Liver Induced by a Methionine- and Choline-Deficient Diet.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Choline; Diet; Fatty Liver; Glutathione; Glycogen; Hydrazines; Immunohistochemistry; Liver; Male; Methionine; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2016 |
Effects of Nonpurified and Choline Supplemented or Nonsupplemented Purified Diets on Hepatic Steatosis and Methionine Metabolism in C3H Mice.
Topics: Animals; Choline; Diet; Dietary Fats; Dietary Sucrose; Dietary Supplements; Fatty Liver; Feeding Behavior; Female; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |
Hyperhomocysteinemia activates the aryl hydrocarbon receptor/CD36 pathway to promote hepatic steatosis in mice.
Topics: Animals; CD36 Antigens; Fatty Liver; Hepatocytes; Hyperhomocysteinemia; Lipid Metabolism; Lipoxins; Liver; Male; Methionine; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon | 2016 |
Ischemia-Reperfusion Injury in Fatty Liver Is Mediated by Activated NADPH Oxidase 2 in Rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cells, Cultured; Choline Deficiency; Deoxyguanosine; Disease Models, Animal; Enzyme Inhibitors; Fatty Liver; HMGB1 Protein; Inflammation Mediators; Interleukin-6; Liver; Macrophages; Male; Membrane Glycoproteins; Methionine; NADPH Oxidase 2; NADPH Oxidases; Necrosis; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Time Factors; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginine; Choline; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Male; Methionine; Rats; Rats, Wistar | 2016 |
In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.
Topics: Animals; Betaine; Body Weight; Chickens; Corticosterone; DNA Methylation; DNA, Mitochondrial; Eating; Epigenesis, Genetic; Fatty Liver; Liver; Male; Methionine; Zygote | 2017 |
A compromised liver alters polychlorinated biphenyl-mediated toxicity.
Topics: Adipokines; Animals; Aroclors; Biomarkers; Blood Glucose; Cardiovascular Diseases; Choline; Diet; Disease Models, Animal; Energy Metabolism; Fatty Liver; Gene Expression; Homeostasis; Inflammation; Liver; Liver Cirrhosis; Male; Methionine; Mice, Inbred C57BL; Polychlorinated Biphenyls | 2017 |
Influence of hyperglycemia on liver inflammatory conditions in the early phase of non-alcoholic fatty liver disease in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Hyperglycemia; Inflammation; Liver; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha | 2017 |
Suv39h2 deficiency ameliorates diet-induced steatosis in mice.
Topics: Animals; Blotting, Western; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Gene Expression; Histone-Lysine N-Methyltransferase; Liver; Liver Cirrhosis; Methionine; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Up-Regulation | 2017 |
MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes.
Topics: Adipocytes; Adipogenesis; Adiponectin; Alanine Transaminase; AMP-Activated Protein Kinase Kinases; Animals; Choline Deficiency; Dietary Fats; Disease Models, Animal; Fatty Acid-Binding Proteins; Fatty Liver; Female; Hepatitis; Hepatocytes; Lipid Peroxides; Methionine; Mice; Mice, Inbred C57BL; PPAR gamma; Protein Kinases; Triglycerides | 2008 |
Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis.
Topics: Animals; Carnitine O-Palmitoyltransferase; Cell Line; Choline Deficiency; Diet; Fatty Acids; Fatty Liver; Interleukin-6; Kupffer Cells; Lipopolysaccharides; Liver; Liver Cirrhosis; Macrophages; Male; Methionine; ortho-Aminobenzoates; Oxidation-Reduction; Oxidative Stress; PPAR alpha; Rats; Rats, Inbred OLETF; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation | 2008 |
Hepatic metabolism of glucose and linoleic acid varies in relation to susceptibility to fatty liver in ad libitum-fed Muscovy and Pekin ducks.
Topics: Animal Feed; Animals; Disease Susceptibility; Ducks; Fatty Liver; Genotype; Glucose; Linoleic Acid; Lipoproteins, VLDL; Liver; Methionine; Models, Animal; Poultry Diseases; Species Specificity; Tissue Culture Techniques | 2009 |
Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.
Topics: Animals; Catalase; Cells, Cultured; Choline Deficiency; Diet; Disease Progression; Enzyme Activation; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha; Reactive Oxygen Species; Receptors, Adiponectin; Signal Transduction; Transforming Growth Factor beta1 | 2008 |
Is the hepatic metabolism of glucose and linoleic acid influenced by species in overfed ducks?
Topics: Animals; Ducks; Eating; Fatty Liver; Glucose; In Vitro Techniques; Linoleic Acid; Lipoproteins, VLDL; Liver; Male; Methionine; Species Specificity | 2008 |
VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
Topics: Actins; Animals; Choline Deficiency; Collagen Type I; Diet; Disease Models, Animal; Fatty Liver; Female; Liver Cirrhosis; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Probiotics; Signal Transduction; Transforming Growth Factor beta | 2009 |
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase.
Topics: Animals; Apoptosis; Cell Survival; Choline Deficiency; Disease Models, Animal; Fatty Acids; Fatty Liver; Fluorescent Antibody Technique; Hepatocytes; Immunoblotting; Lipids; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Small Interfering; Stearoyl-CoA Desaturase | 2009 |
Utility of a 13C-methacetin breath test in evaluating hepatic injury in rats.
Topics: Acetamides; Administration, Oral; Animals; Breath Tests; Carbon Isotopes; Choline Deficiency; Disease Models, Animal; Fatty Liver; Hepatectomy; Injections, Intraperitoneal; Liver; Liver Cirrhosis; Liver Failure, Acute; Liver Function Tests; Male; Methionine; Organ Size; Predictive Value of Tests; Rats; Rats, Wistar; Severity of Illness Index; Thioacetamide; Time Factors | 2008 |
Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation.
Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Choline Deficiency; DNA Primers; Fatty Liver; Female; Inflammation; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pioglitazone; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones | 2009 |
TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase.
Topics: Adenosylhomocysteinase; Animals; Base Sequence; Disease Models, Animal; DNA Primers; Fatty Liver; Humans; Larva; Lipogenesis; Liver Diseases; Male; Methionine; Mitochondria, Liver; Models, Biological; Mutation; Oxidative Stress; Phenotype; Species Specificity; Tubercidin; Tumor Necrosis Factor-alpha; Zebrafish; Zebrafish Proteins | 2009 |
Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression.
Topics: Alanine Transaminase; Animals; Apoptosis; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Choline Deficiency; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; fas Receptor; Fatty Liver; Gene Expression Regulation; Insulin-Like Growth Factor I; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Nutritional Status; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Time Factors; Tumor Suppressor Protein p53 | 2009 |
Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis.
Topics: Animals; Blood Glucose; Body Weight; Choline Deficiency; Fatty Acids; Fatty Liver; In Situ Nick-End Labeling; Lipid Peroxidation; Lipids; Liver; Male; Methionine; Mice; Polymerase Chain Reaction; Sucrose | 2009 |
Metabolism of methionine in vivo: impact of pregnancy, protein restriction, and fatty liver disease.
Topics: Animals; Diet, Protein-Restricted; Disease Models, Animal; Fatty Liver; Female; Fetal Growth Retardation; Folic Acid; Humans; Insulin Resistance; Methionine; Models, Animal; Pregnancy | 2009 |
Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue.
Topics: Adipocytes; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cell Line; Cell Size; Chemokine CCL2; Choline Deficiency; Collagen Type I; Disease Models, Animal; Disease Progression; Drinking; Eating; Fatty Liver; Intra-Abdominal Fat; Liver; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Organ Size; Oxidative Stress; Receptors, CCR2; RNA, Messenger; Telmisartan; Transforming Growth Factor beta1; Triglycerides | 2009 |
Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet.
Topics: Animals; Choline Deficiency; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Folic Acid Deficiency; Histones; Liver; Male; Methionine; Mice; Mice, Inbred Strains; Phenotype; Species Specificity | 2009 |
Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azepines; Chemokine CCL2; Chemokines; Choline Deficiency; Fatty Liver; Hepatitis; Indoles; Lipids; Liver Cirrhosis, Experimental; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; Triglycerides | 2009 |
Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats.
Topics: Animals; Apoptosis; Biomarkers; Choline; Choline Deficiency; Cytokines; Diet; Fatty Liver; Glutathione; Histocytochemistry; Liver; Male; Malondialdehyde; Melatonin; Methionine; Oxidative Stress; Rats; Rats, Wistar; Statistics, Nonparametric; Superoxide Dismutase | 2009 |
Children's toxicology from bench to bed--Liver Injury (2): Mechanism of antioxidant therapy for nonalcoholic fatty liver disease.
Topics: alpha-Tocopherol; Animals; Antioxidants; Carrier Proteins; Choline Deficiency; Disease Models, Animal; Fatty Liver; Liver; Male; Methionine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 2009 |
MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice.
Topics: Animals; Central Nervous System Depressants; Choline Deficiency; Cytokines; Diet; Ethanol; Fatty Liver; Fatty Liver, Alcoholic; Female; Inflammation; Lipid Metabolism; Liver; Liver Function Tests; Methionine; Mice; Mice, Inbred C57BL; MicroRNAs | 2009 |
Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.
Topics: Animals; Case-Control Studies; Cell Line; Cell Transdifferentiation; Choline Deficiency; Disease Progression; Epithelial Cells; Fatty Liver; Fibroblasts; Hedgehog Proteins; Humans; Liver Cirrhosis, Experimental; Methionine; Mice; Mice, Inbred C57BL; Patched Receptors; Patched-1 Receptor; Rats; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Signal Transduction; Veratrum Alkaloids | 2009 |
Teucrium polium in prevention of steatohepatitis in rats.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Choline Deficiency; Disease Models, Animal; Fatty Liver; Hepatitis; Lipoproteins; Liver; Male; Methionine; Oxidoreductases; Plant Extracts; Rats; Teucrium | 2009 |
Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.
Topics: Actins; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Choline Deficiency; Diabetes Complications; Disease Models, Animal; Enzyme Inhibitors; Fatty Liver; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Obesity | 2009 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response | 2009 |
Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice.
Topics: Animals; Carrier Proteins; Choline Deficiency; Diet; Fatty Liver; Female; Fibrosis; Hepatitis; Interferon-gamma; Interleukin-1beta; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; NF-kappa B; Oxidative Stress; Thioredoxins; Triglycerides; Tumor Necrosis Factor-alpha | 2009 |
Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice.
Topics: Animals; Cell Line; Cells, Cultured; Disease Models, Animal; Fatty Liver; Heme Oxygenase-1; Hemin; Hepatocytes; Liver; Male; Mesoporphyrins; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha; Sterol Regulatory Element Binding Protein 1 | 2010 |
Curcumin limits the fibrogenic evolution of experimental steatohepatitis.
Topics: Actins; Alanine Transaminase; Animals; CD11b Antigen; Cells, Cultured; Chemokine CCL2; Choline; Choline Deficiency; Collagen Type I; Curcumin; Diet; Enzyme Inhibitors; Fatty Liver; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Muscle, Smooth; Oxidative Stress; Reactive Oxygen Species; Tissue Inhibitor of Metalloproteinase-1 | 2010 |
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis.
Topics: Animals; Choline; Cyclooxygenase 2; Disease Progression; Fatty Liver; Food, Formulated; Interleukin-1beta; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Tumor Necrosis Factor-alpha | 2010 |
Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.
Topics: Animal Feed; Animals; Choline; Choline Deficiency; Disease Progression; Fatty Liver; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; RNA, Messenger | 2010 |
IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis.
Topics: Animal Feed; Animals; Apoptosis; Choline; Disease Models, Animal; Fatty Liver; Inflammation; Interleukin-6; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; PPAR gamma | 2009 |
Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet.
Topics: Animals; Choline; Disease Models, Animal; Endoplasmic Reticulum; Fatty Liver; Inflammation; Liver Cirrhosis; Male; Methionine; Oxidative Stress; Rats; Rats, Wistar | 2010 |
Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.
Topics: Alanine Transaminase; Animals; Blood Coagulation; Blood Coagulation Factors; Chemokine CCL2; Choline; Diet; Fatty Liver; Gene Expression Regulation; Inflammation; Liver; Methionine; Mice; Mice, Inbred C57BL; Models, Biological; Receptor, PAR-1; Thrombin; Thromboplastin; Triglycerides | 2010 |
Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis.
Topics: Animals; beta Catenin; Bile Acids and Salts; Cholesterol; Choline Deficiency; Diet; Fatty Liver; Genetic Predisposition to Disease; Homeostasis; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Knockout; Organ Specificity; Stress, Physiological | 2010 |
Methionine limitation results in increased hepatic FAS activity, higher liver 18:1 to 18:0 fatty acid ratio and hepatic TAG accumulation in Atlantic salmon, Salmo salar.
Topics: Amino Acids; Animals; Fatty Acid Synthases; Fatty Acids; Fatty Liver; Liver; Methionine; Salmo salar; Triglycerides | 2010 |
Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.
Topics: Animals; Blood Glucose; Cell Death; Cells, Cultured; Choline Deficiency; Diet; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Fatty Liver; Hepatocytes; Insulin; Methionine; Mice; Mice, Knockout; Molecular Chaperones; Palmitic Acid; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Transcription Factor CHOP; Unfolded Protein Response | 2010 |
[Involvement of endoplasmic reticulum stress in development of fatty liver fibrosis induced by methionine-choline-deficient diet in rats].
Topics: Animals; Apoptosis; Caspases; Cell Proliferation; Choline; Choline Deficiency; Diet; Disease Models, Animal; Endoplasmic Reticulum; Fatty Liver; Liver; Liver Cirrhosis; Male; Methionine; Random Allocation; Rats; Rats, Wistar; RNA, Messenger | 2010 |
Impaired liver regeneration of steatotic rats after portal vein ligation: a particular emphasis on (99m)Tc-DISIDA scintigraphy and adiponectin signaling.
Topics: Adiponectin; Animals; Apoptosis; Choline Deficiency; Cytokines; Disease Models, Animal; Fatty Liver; Hepatectomy; Hepatocytes; Kupffer Cells; Ligation; Liver Regeneration; Male; Methionine; Portal Vein; PPAR alpha; Preoperative Care; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; RNA, Messenger; Signal Transduction; Technetium Tc 99m Disofenin | 2010 |
[Mechanism of hepatocyte regeneration inhibition in rats with liver fibrosis induced by lipogenic methionine-choline- deficient diet].
Topics: Animals; Apoptosis; Cell Proliferation; Choline Deficiency; Diet; Fatty Liver; Hepatocytes; Liver Cirrhosis; Methionine; Rats | 2009 |
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet.
Topics: Adaptor Proteins, Signal Transducing; Animals; Body Weight; Choline Deficiency; Cytoskeletal Proteins; Disease Models, Animal; Fatty Acids; Fatty Liver; Genotype; Glutathione; Glutathione Transferase; Isoenzymes; Kelch-Like ECH-Associated Protein 1; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Organ Size; Phenotype; RNA, Messenger; Severity of Illness Index; Signal Transduction | 2010 |
Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice.
Topics: Alanine Transaminase; Animals; Choline; Choline Deficiency; Diet; Fatty Liver; Genes; Interleukin-6; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha; Receptors, Interleukin-6; Signal Transduction; Sterol Regulatory Element Binding Protein 1 | 2010 |
PPARgamma is essential for protection against nonalcoholic steatohepatitis.
Topics: Adenoviridae; Animals; Choline Deficiency; Fatty Liver; Gene Transfer Techniques; Genetic Therapy; Methionine; Mice; PPAR gamma; Rosiglitazone; Thiazolidinediones | 2010 |
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.
Topics: Animal Feed; Animals; Ceramides; Choline; Fatty Liver; Glutathione; Inflammation; Lipids; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Prodrugs; S-Adenosylmethionine; Sphingomyelin Phosphodiesterase | 2010 |
Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis.
Topics: Animals; Choline Deficiency; Collagen Type I; Dietary Fats; Dietary Fats, Unsaturated; Disease Models, Animal; Fatty Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2010 |
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.
Topics: Animals; Choline Deficiency; Fatty Liver; Fibrosis; Hedgehog Proteins; Hepatic Stellate Cells; Humans; Liver; Methionine; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; Signal Transduction | 2010 |
Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Blood Glucose; Cholesterol; Choline Deficiency; Diet; Dietary Sucrose; Fatty Liver; Fructose; Gene Expression Profiling; Gene Expression Regulation; Lipid Peroxidation; Lipogenesis; Liver; Male; Methionine; Mice; Mice, Mutant Strains; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2010 |
Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice.
Topics: Acyl Coenzyme A; Acyl-CoA Oxidase; Animals; Antioxidants; Carnitine O-Palmitoyltransferase; Choline; Diet; Disease Progression; Fatty Liver; Glutathione; Hepatocytes; Inflammation; Ion Channels; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Oxidative Stress; Uncoupling Protein 2 | 2010 |
Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Caspase Inhibitors; Choline Deficiency; Cysteine Proteinase Inhibitors; Dietary Fats; Disease Models, Animal; Fatty Liver; Humans; Male; Methionine; Mice; Mice, Inbred C3H; Mice, Obese; Oxidative Stress | 2010 |
Stress signaling in the methionine-choline-deficient model of murine fatty liver disease.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 12; Choline Deficiency; Disease Models, Animal; DNA-Binding Proteins; Fatty Liver; Genes, MHC Class II; JNK Mitogen-Activated Protein Kinases; Liver; Male; Methionine; Mice; Mice, Inbred C3H; Oxidative Stress; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors; Triglycerides | 2010 |
Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet.
Topics: Animals; Chemokine CCL2; Choline Deficiency; Diet; Fatty Liver; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Transforming Growth Factor beta | 2010 |
Eicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet.
Topics: Actins; Animals; Choline Deficiency; Connective Tissue Growth Factor; Disease Progression; Eicosapentaenoic Acid; Fatty Liver; Liver; Liver Cirrhosis; Male; Methionine; Non-alcoholic Fatty Liver Disease; Procollagen; Rats; Rats, Wistar; Reactive Oxygen Species; Transforming Growth Factor beta1; Treatment Outcome; Triglycerides | 2011 |
Increased susceptibility to experimental steatohepatitis induced by methionine-choline deficiency in HBs-Tg mice.
Topics: Alanine Transaminase; Animal Feed; Animals; Choline Deficiency; Disease Models, Animal; Disease Susceptibility; Fatty Liver; Hepatitis B Surface Antigens; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proliferating Cell Nuclear Antigen; Statistics, Nonparametric | 2010 |
Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.
Topics: Animals; Cell Line; Choline Deficiency; Diet; Fatty Liver; Hedgehog Proteins; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Osteopontin; Up-Regulation; Veratrum Alkaloids | 2011 |
Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice.
Topics: Adenoviridae; Anilides; Animals; beta-Galactosidase; Choline; Diet; Fatty Liver; Genetic Vectors; Inflammation; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Methionine; Mice; Mice, Inbred C57BL; PPAR gamma; Random Allocation; Rosiglitazone; Thiazolidinediones; Transfection | 2011 |
Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice.
Topics: Animals; Apoptosis; Fatty Liver; Heme Oxygenase-1; Hemin; Hepatocytes; In Situ Nick-End Labeling; Male; Methionine; Mice; Mice, Inbred C57BL; Protoporphyrins | 2010 |
The mechanism of action of the antifatty liver factor of the pancreas; free methionine prevents fatty livers in completely depancreatized dogs maintained with insulin and fed a lean meat diet.
Topics: Animals; Diet; Dogs; Fatty Liver; Insulin; Liver; Meat; Methionine; Pancreas | 1945 |
Teucrium polium reversed the MCD diet-induced liver injury in rats.
Topics: Animals; Antioxidants; Caspase 3; Choline Deficiency; Fatty Liver; Gene Expression; Glutathione Peroxidase; Liver; Male; Malondialdehyde; MAP Kinase Kinase 4; Methionine; Plant Extracts; Rats; Rats, Inbred Strains; Superoxide Dismutase; Teucrium; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2011 |
Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis.
Topics: Adipose Tissue; Animals; Choline Deficiency; Diet; Eating; Fatty Acids; Fatty Liver; Gas Chromatography-Mass Spectrometry; Hepatitis; Hepatocytes; Immunohistochemistry; Kinetics; Lipogenesis; Liver; Male; Metabolic Networks and Pathways; Methionine; Mice; Mice, Inbred C57BL; Organ Size; Palmitic Acids; Triglycerides | 2011 |
Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis.
Topics: Animals; Cell Proliferation; Choline Deficiency; Constitutive Androstane Receptor; Disease Models, Animal; Fatty Liver; Genes, myc; Hep G2 Cells; Humans; Ki-67 Antigen; Liver Neoplasms, Experimental; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Pyridines; Receptors, Cytoplasmic and Nuclear | 2011 |
Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
Topics: Actins; Alanine Transaminase; Animals; Choline Deficiency; Collagen; Fatty Liver; Female; Genotype; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Lymphocyte Antigen 96; Matrix Metalloproteinase 2; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phenotype; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Tissue Inhibitor of Metalloproteinase-1; Toll-Like Receptor 4; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha | 2011 |
Reversal of hepatic steatosis by omega-3 fatty acids measured non-invasively by (1) H-magnetic resonance spectroscopy in a rat model.
Topics: Animals; Antioxidants; Choline Deficiency; Chromatography, Gas; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; Fatty Liver; Inflammation Mediators; Interleukin-6; Lipid Metabolism; Liver; Magnetic Resonance Spectroscopy; Male; Methionine; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention.
Topics: Animals; Blood Glucose; Carbon; Cholesterol; Choline; Dietary Fats; Fatty Liver; Hyperglycemia; Insulin; Insulin Resistance; Liver; Methionine; Mice; Mice, Inbred C57BL; Obesity; Triglycerides | 2011 |
Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice.
Topics: Actins; Alanine Transaminase; Animals; Aspartate Aminotransferases; Choline Deficiency; Enzyme Induction; Fatty Liver; Heme Oxygenase-1; Hemin; Lipid Peroxides; Liver; Liver Cirrhosis; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Methionine; Mice; Mice, Inbred C57BL; Protoporphyrins; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice.
Topics: Animals; Antibodies, Neutralizing; Apoptosis; Choline Deficiency; Diet; DNA-(Apurinic or Apyrimidinic Site) Lyase; Fatty Liver; Fibrosis; Gene Expression; Hepatocytes; Injections, Intraperitoneal; Interleukin-6; Leptin; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor | 2011 |
Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Biopsy; Choline Deficiency; Cytokines; Disease Models, Animal; Fatty Liver; Female; Humans; Interferon Type I; Liver; Methionine; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Poly I-C; Receptor-Interacting Protein Serine-Threonine Kinases; RNA, Double-Stranded | 2011 |
Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine.
Topics: Adipokines; Adult; Aged; Calorimetry, Indirect; Case-Control Studies; Cysteine; Fatty Liver; Female; Glutathione; Homocysteine; Humans; Inflammation Mediators; Insulin Resistance; Liver; Male; Methionine; Methylation; Middle Aged; Non-alcoholic Fatty Liver Disease; Phenylalanine; Proteins; Urea; Young Adult | 2011 |
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells.
Topics: Animals; Apoptosis; Caspase 1; Choline Deficiency; Dietary Fats; Disease Models, Animal; Endotoxins; Fatty Acids; Fatty Liver; Female; Hepatocytes; Immune System; Inflammasomes; Interleukin-1beta; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha | 2011 |
The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Diet; Disease Models, Animal; Disease Progression; Fatty Liver; Ischemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Peroxidase; Reperfusion Injury | 2011 |
Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis.
Topics: Activating Transcription Factor 6; Animal Feed; Animals; Choline; Choline Deficiency; Cytokines; Diabetes Mellitus, Experimental; Eukaryotic Initiation Factor-2; Fatty Liver; Female; JNK Mitogen-Activated Protein Kinases; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Non-alcoholic Fatty Liver Disease; Obesity; Protein Phosphatase 1; Signal Transduction; Transcription Factor CHOP; Unfolded Protein Response | 2011 |
The non-invasive (13)C-methionine breath test detects hepatic mitochondrial dysfunction as a marker of disease activity in non-alcoholic steatohepatitis.
Topics: Adult; Aged; Biomarkers; Breath Tests; Carbon Isotopes; Case-Control Studies; Cross-Sectional Studies; Fatty Liver; Female; Humans; Male; Methionine; Middle Aged; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; ROC Curve | 2011 |
Omega-3 fatty acids reduce hepatic steatosis and consequently attenuate ischemia-reperfusion injury following partial hepatectomy in rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Choline Deficiency; Dietary Supplements; Fatty Acids, Monounsaturated; Fatty Acids, Omega-3; Fatty Liver; Hepatectomy; Liver; Male; Methionine; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2011 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Cysteine; Diet; Enzyme Inhibitors; Fatty Liver; Glutathione; Homeostasis; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 2011 |
Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet.
Topics: Alanine Transaminase; Animals; Bezafibrate; Calcium Channel Blockers; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Hypolipidemic Agents; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Nifedipine; Non-alcoholic Fatty Liver Disease; PPAR gamma; Rats; Rats, Wistar | 2012 |
Decreased accumulation of ultrasound contrast in the liver of nonalcoholic steatohepatitis rat model.
Topics: Animals; Body Weight; Choline Deficiency; Contrast Media; Diet; Disease Models, Animal; Fatty Liver; Kupffer Cells; Leptin; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Ultrasonography | 2011 |
Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease.
Topics: Animals; Choline Deficiency; Diacylglycerol O-Acyltransferase; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Fatty Acid Synthases; Fatty Acid Transport Proteins; Fatty Acids; Fatty Liver; Fibrosis; Gene Expression; Glycerol-3-Phosphate O-Acyltransferase; Lipid Mobilization; Lipogenesis; Liver; Membrane Proteins; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphorylation; Regulatory Factor X Transcription Factors; Sterol Regulatory Element Binding Protein 1; Transcription Factor CHOP; Transcription Factors | 2011 |
Steatotic liver: a suitable source for the isolation of hepatic progenitor cells.
Topics: Animals; Antigens, Differentiation; Antigens, Neoplasm; Biomarkers; Cell Adhesion Molecules; Cell Separation; Choline Deficiency; Disease Models, Animal; Epithelial Cell Adhesion Molecule; Fatty Liver; Flow Cytometry; Humans; Liver; Male; Methionine; Rats; Stem Cells; Thy-1 Antigens; Time Factors | 2011 |
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Choline Deficiency; Disease Models, Animal; DNA, Mitochondrial; Fatty Acids, Nonesterified; Fatty Liver; Gene Expression Regulation; Hep G2 Cells; Humans; Liver; Lysosomes; Membrane Potential, Mitochondrial; Methionine; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Oxidative Stress; PPAR gamma; Rats; Rats, Inbred OLETF; Rats, Long-Evans; RNA, Messenger; Thioctic Acid; Time Factors | 2011 |
A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation.
Topics: Animals; Choline Deficiency; Diet; Disease Models, Animal; DNA-Binding Proteins; Fatty Liver; Feasibility Studies; Gene Expression Regulation; Liver Transplantation; Male; Methionine; Mice; Mice, SCID; Mice, Transgenic; Non-alcoholic Fatty Liver Disease; Phenotype; Tumor Necrosis Factor-alpha | 2012 |
Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis.
Topics: Animals; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Biliary Tract; Biological Transport; Choline Deficiency; Diet; Ezetimibe; Fatty Liver; Glucuronosyltransferase; Intestinal Mucosa; Liver; Male; Membrane Transport Proteins; Methionine; Multidrug Resistance-Associated Proteins; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley | 2012 |
Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver.
Topics: Adiponectin; Aged; Animals; Bile Ducts; Choline; Diet; Fatty Liver; Female; Hepatic Stellate Cells; Hepatocytes; Humans; Kupffer Cells; Liver; Male; Methionine; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Primary Cell Culture; Receptors, Chemokine; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2012 |
Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline; Choline Deficiency; Cytochrome P-450 CYP2E1; Diet; Disease Models, Animal; Endoplasmic Reticulum Stress; Fatty Liver; Humans; Inflammation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2012 |
Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline Deficiency; Cytokines; Diet; Fatty Liver; Gene Expression; Glutathione; Insulin Resistance; Isoprostanes; JNK Mitogen-Activated Protein Kinases; Liver; Male; Methionine; Mice; Myocardium; Nitrates; Nitrites; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Silybin; Silymarin; Statistics, Nonparametric | 2012 |
Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis.
Topics: Analysis of Variance; Animals; Bile Acids and Salts; Biopsy, Needle; Cells, Cultured; Diet; Disease Models, Animal; Fatty Liver; Hepatocytes; Homeostasis; Immunohistochemistry; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phospholipids; Polymerase Chain Reaction; Random Allocation | 2012 |
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Topics: Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Choline; Colon; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Fatty Liver; Inflammasomes; Inflammation; Interleukin-18; Male; Metagenome; Methionine; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Cell Surface; RNA, Ribosomal, 16S; Toll-Like Receptor 4; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha | 2012 |
Pentoxifylline attenuates methionine- and choline-deficient-diet-induced steatohepatitis by suppressing TNF-α expression and endoplasmic reticulum stress.
Topics: Alanine Transaminase; Animals; Cell Line; Choline Deficiency; Diet; Endoplasmic Reticulum Stress; Fatty Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha; Unfolded Protein Response | 2012 |
Identification of liver proteins altered by type 2 diabetes mellitus in obese subjects.
Topics: Adult; Aldehydes; Biomarkers; Biopsy; Diabetes Mellitus, Type 2; Electrophoresis, Gel, Two-Dimensional; Fatty Liver; Female; Glutathione; Humans; Liver; Methionine; Middle Aged; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Obesity, Morbid; Oxidative Stress; Protein Carbonylation; Proteins; Proteomics; Severity of Illness Index; Spain; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anticarcinogenic Agents; Choline Deficiency; Cytoskeletal Proteins; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Iron; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver; Male; Methionine; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Real-Time Polymerase Chain Reaction; Sulfoxides; Thiocyanates | 2012 |
Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress.
Topics: Animals; Ascorbic Acid; Choline Deficiency; Diet; Disease Models, Animal; Ethylenediamines; Fatty Liver; Humans; Lipid Peroxidation; Methionine; Organometallic Compounds; Oxidative Stress; Rats; Salicylates | 2012 |
Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis.
Topics: Actins; Animals; Antigens, Differentiation; Caspase 1; Caspase 3; Choline Deficiency; Clodronic Acid; Collagen Type I; Fatty Liver; Hepatic Stellate Cells; Hepatocytes; Inflammation; Interleukin-1beta; Kupffer Cells; LIM Domain Proteins; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Nuclear Proteins; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2012 |
[Mechanism of hepatocyte apoptosis in rats with liver fibrosis induced by lipogenic methionine-choline-deficient diet].
Topics: Animals; Apoptosis; Caspase 12; Caspase 3; Caspase 7; Caspase 9; Choline Deficiency; Diet; Endoplasmic Reticulum Stress; Fatty Liver; Heat-Shock Proteins; Hepatocytes; Liver Cirrhosis; Male; Methionine; Mitogen-Activated Protein Kinases; Non-alcoholic Fatty Liver Disease; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction | 2012 |
Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet.
Topics: Animals; Blood Glucose; Blotting, Western; Body Weight; Cholesterol; Choline Deficiency; Diet; Endoplasmic Reticulum; Fatty Liver; Gene Expression; Inflammation; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Molecular Chaperones; Phenylbutyrates; Real-Time Polymerase Chain Reaction; Stress, Physiological; Taurochenodeoxycholic Acid | 2012 |
Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Choline Deficiency; Disease Models, Animal; Fatty Liver; Homeostasis; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Obese; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Silybin; Silymarin; Translational Research, Biomedical | 2012 |
p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.
Topics: Animals; Apoptosis; Caspase 3; Choline Deficiency; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatocytes; Humans; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Primary Cell Culture; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; RNA, Messenger; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transforming Growth Factor beta; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.
Topics: Alanine Transaminase; Animals; Antimycin A; Apoptosis; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Free Radical Scavengers; Glutathione; Hepatocytes; Hydrogen Peroxide; Male; Metalloporphyrins; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitochondria, Liver; Oxidation-Reduction; Pentanoic Acids; Peroxiredoxin III; Primary Cell Culture; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Thioredoxins | 2012 |
Altered arsenic disposition in experimental nonalcoholic fatty liver disease.
Topics: Animals; Arsenates; Arsenic Trioxide; Arsenicals; Biotransformation; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Environmental Pollutants; Fatty Liver; Kidney; Liver; Male; Methionine; Methyltransferases; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Non-alcoholic Fatty Liver Disease; Oxides | 2012 |
Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Benzofurans; Choline; Clodronic Acid; Diet, High-Fat; DNA Primers; Fatty Acids, Unsaturated; Fatty Liver; Gadolinium; Hemodynamics; Hypertension, Portal; Insulin Resistance; Kupffer Cells; Leptin; Methionine; Methoxamine; Microcirculation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfonylurea Compounds; Thiobarbituric Acid Reactive Substances; Thromboxane A2 | 2012 |
Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Choline Deficiency; Diet; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; GATA4 Transcription Factor; Glucagon-Like Peptide 1; Jejunum; Lipid Metabolism; Liver Cirrhosis; Male; Methionine; Mice; Mice, Knockout; Protein Kinases; Sterol Regulatory Element Binding Protein 1; Thiobarbituric Acid Reactive Substances; Triglycerides | 2012 |
Glycine alleviates liver injury induced by deficiency in methionine and or choline in rats.
Topics: Animals; Antioxidants; Choline Deficiency; Fatty Liver; Glycine; Lipid Metabolism; Lipid Peroxidation; Male; Methionine; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley | 2012 |
Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis.
Topics: Animals; Biomarkers; Choline; Choline Deficiency; Collagen Type I; Collagen Type III; Cyclooxygenase 2; Diet; Disease Models, Animal; Fatty Liver; Fibrosis; HMGB1 Protein; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Quercetin; RNA, Messenger; Smad Proteins; Thiobarbituric Acid Reactive Substances; Toll-Like Receptor 4; Up-Regulation | 2012 |
Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury.
Topics: Animals; Choline Deficiency; Fatty Liver; Inflammation; Male; Methionine; Mice; Prohibitins; Repressor Proteins; Transcriptome | 2012 |
The pro-inflammatory action of tumour necrosis factor-α in non-alcoholic steatohepatitis is independent of the NSMAF gene product.
Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Intracellular Signaling Peptides and Proteins; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Real-Time Polymerase Chain Reaction; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factor-alpha | 2013 |
Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production.
Topics: Animals; Chemokine CCL2; Chemokine CXCL10; Choline; Diet; Disease Models, Animal; Fatty Liver; Female; Humans; Kupffer Cells; Methionine; Mice; Mice, Inbred C57BL; Monocytes; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha | 2012 |
Dandelion leaf extract protects against liver injury induced by methionine- and choline-deficient diet in mice.
Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Humans; Interleukin-6; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Plant Extracts; Plant Leaves; Protective Agents; Taraxacum; Tumor Necrosis Factor-alpha | 2013 |
Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models.
Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Choline Deficiency; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Hepatocytes; In Vitro Techniques; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Neovascularization, Pathologic; Non-alcoholic Fatty Liver Disease; Placenta Growth Factor; Pregnancy Proteins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Choline Deficiency; Diet, Fat-Restricted; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Humans; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred A; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Specific Pathogen-Free Organisms; Time Factors | 2013 |
Quercetin decreases liver damage in mice with non-alcoholic steatohepatitis.
Topics: Animals; Antioxidants; Choline Deficiency; Comet Assay; Diet; Disease Models, Animal; DNA Damage; Fatty Liver; Lipid Peroxidation; Liver Function Tests; Male; Methionine; Mice; Mice, Inbred C57BL; Molecular Structure; Oxidative Stress; Quercetin | 2013 |
Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.
Topics: Animal Feed; Animals; Anticholesteremic Agents; Choline Deficiency; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Fatty Acids; Fatty Liver; Female; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microsomes; Mixed Function Oxygenases; Pyrimidines; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Severity of Illness Index; Transcription Factors; Triglycerides | 2003 |
Development of portal fatty liver in rats on corn diets; response to lipotropic agents.
Topics: Animals; Choline; Diet; Fatty Liver; Lipotropic Agents; Liver Diseases; Methionine; Rats; Vitamin B 12; Zea mays | 1954 |
[Action of lipotropic factors on hepatic steatosis in experimental hypoxia].
Topics: Choline; Fatty Liver; Humans; Hypoxia; Lipotropic Agents; Liver Diseases; Methionine | 1955 |
[Therapy of the fatty liver with lipotropic substances].
Topics: Choline; Fatty Liver; Humans; Lecithins; Lipotropic Agents; Liver Diseases; Methionine; Phosphatidylcholines | 1956 |
[The action of various lipotropic substances on the steatogenic effects of carbon tetrachloride as a function of time].
Topics: Carbon Tetrachloride; Choline; Fatty Liver; Lipotropic Agents; Methionine | 1956 |
[Simultaneous administration of alcohol and lipotropic drugs in chronic alcoholics; behavior of hepatic steatosis studied by serial punch biopsies].
Topics: Alcoholics; Alcoholism; Biopsy; Choline; Fatty Liver; Humans; Lipotropic Agents; Methionine | 1957 |
Effect of choline on the incorporation of 35S-L-methionine into liver protein of rats with fatty livers.
Topics: Animals; Choline; Fatty Liver; Liver; Methionine; Proteins; Rats | 1958 |
Sex difference in induction of periportal fatty liver by methionine deficiency in the rat.
Topics: Animals; Fatty Liver; Methionine; Rats; Sex Characteristics | 1958 |
Kwashiorkor type of fatty liver in primates.
Topics: Animals; Betaine; Body Weight; Choline; Diet; Dietary Supplements; Fatty Liver; Kwashiorkor; Lipids; Methionine; Primates; Proteins | 1958 |
[The prevention of lipophanerosis of the liver by lipotropic substances].
Topics: Biomedical Research; Choline; Fatty Liver; Inositol; Lipotropic Agents; Liver; Methionine | 1958 |
Turnover rates of liver protein in rats with fatty livers as measured with 35S-methionine.
Topics: Animals; Biochemical Phenomena; Fatty Liver; Liver; Methionine; Proteins; Rats | 1959 |
[Study of the intestinal absorption of d-l-methionine in the course of hepatic steatosis].
Topics: Fatty Liver; Humans; Intestinal Absorption; Intestines; Liver Diseases; Methionine | 1959 |
[Acceleration of intestinal absorption of d-l-methionine in the course of hepatic steatoses. Control of the phenomen on by the study of S 35-d-l-methionine absorption].
Topics: Fatty Liver; Humans; Intestinal Absorption; Liver Diseases; Methionine; Radioactivity; Sulfur; Sulfur Radioisotopes | 1960 |
Experimental dietary cirrhosis.
Topics: Animals; Choline; Cystine; Diet; Fatty Liver; Humans; Liver Cirrhosis, Experimental; Methionine; Orotic Acid; Protein Deficiency; Siderosis; Vitamin E | 1962 |
INEFFECTIVENESS OF LIPOTROPIC SUBSTANCES IN POSTIRRADIATION FATTY INFILTRATION OF THE LIVER.
Topics: Animals; Choline; Fatty Liver; Lipid Metabolism; Lipotropic Agents; Liver; Methionine; Mice; Radiation Injuries; Radiation Injuries, Experimental; Research | 1963 |
A MARKEDLY ANTI-LIPOTROPIC ACTION OF METHIONINE.
Topics: Chemical Phenomena; Chemistry; Cholesterol; Cystine; Fatty Liver; Glycerides; Lipid Metabolism; Lipotropic Agents; Liver; Methionine; Phospholipids; Protein Deficiency; Rats; Research; Valine | 1963 |
ROLE OF IMPAIRED TRANSMETHYLATION OF EPINEPHRINE IN ETHIONINE-INDUCED HEPATIC FAT ACCUMULATION.
Topics: Adrenalectomy; Cortisone; Epinephrine; Ethionine; Fatty Liver; Lipid Metabolism; Liver; Metabolism; Methionine; Pharmacology; Rats; Research; Toxicology; Transferases | 1963 |
[EXPERIMENTAL DATA ON THE EFFECT OF METHIONINE IN FATTY DYSTROPHY OF THE LIVER].
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Fatty Liver; Hepatitis; Methionine; Rats; Research; Toxicology | 1963 |
HOMOCYSTINURIA: AN ENZYMATIC DEFECT.
Topics: Amino Acids; Blood Protein Disorders; Carbon Isotopes; Child; Cystic Fibrosis; Cystinuria; Fatty Liver; Homocystinuria; Humans; Hypoproteinemia; Intellectual Disability; Ligases; Liver; Methionine; Pancreatic Neoplasms; Proteins; Psoriasis | 1964 |
[HISTOLOGICAL STUDIES OF NUCLEIC ACIDS OF THE LIVER IN DIETARY LIVER DISORDERS. 3. RESULTS WITH A DIET OF BUCKWHEAT FLOUR WITH ADDED AMINO ACIDS].
Topics: Amino Acids; Arginine; Diet; Edible Grain; Fagopyrum; Fatty Liver; Flour; Histidine; Isoleucine; Leucine; Lipotropic Agents; Liver; Lysine; Methionine; Mice; Phenylalanine; Research; RNA; Threonine; Tryptophan; Valine | 1964 |
[HISTOLOGICAL STUDY ON NUCLEIC ACIDS OF THE LIVER IN DIETARY LIVER DISORDERS. 2. THE RESULTS IN THE GROUPS FED BUCKWHEAT WITH ANTI-FATTY LIVER AGENTS].
Topics: Animals; Caseins; Diet; Edible Grain; Fagopyrum; Fatty Liver; Folic Acid; Liver; Methionine; Mice; Nutrition Disorders; Orotic Acid; Research; RNA; Thiamine; Thioctic Acid; Vitamin B Complex | 1964 |
[SOME CONSIDERATIONS ON THE THERAPEUTIC USE OF METHIONINE IN HIGH DOSES].
Topics: Fatty Liver; Hepatic Encephalopathy; Lipid Metabolism; Liver Cirrhosis; Metabolism; Methionine; Neurologic Manifestations; Pharmacology; Toxicology | 1964 |
S35-LABELLED AMINO ACIDS IN EXPERIMENTAL LIVER DISEASE.
Topics: Amino Acids; Animals; Autoradiography; Benzene; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cystine; Ethionine; Fatty Liver; Hepatitis; Hepatitis, Animal; Liver; Methionine; Mice; Pharmacology; Research; Sulfur Isotopes | 1964 |
FATTY LIVERS INDUCED BY AMINO ACIDS AND INFLUENCE OF OTHER AMINO ACIDS ON THEM.
Topics: Amino Acids; Arginine; Aspartic Acid; Choline; Cystine; Dietary Fats; Fatty Liver; Glutamates; Glycine; Leucine; Lipid Metabolism; Liver Function Tests; Methionine; Pharmacology; Rats; Research | 1964 |
METHIONINE DEFICIENCY AND FATTY LIVER IN MALE AND FEMALE RATS.
Topics: Acetates; Carbon Isotopes; Cholesterol; Diet; Fatty Acids; Fatty Liver; Glycerides; Lipid Metabolism; Methionine; Phospholipids; Rats; Research; Sex | 1964 |
RESPONSE OF THE LIVER TO PROLONGED PROTEIN DEPLETION. V. NEUTRAL GLYCERIDES AND CHOLESTEROL; PRODUCTION OF FATTY LIVERS BY CERTAIN AMINO ACIDS FED IN A PROTEIN-FREE RATION.
Topics: Amino Acids; Cholesterol; Cystine; Dietary Fats; Dietary Proteins; Fatty Liver; Glycerides; Leucine; Liver; Methionine; Pharmacology; Phenylalanine; Phospholipids; Protein Deficiency; Proteins; Rats; Research; Valine; Zea mays | 1965 |
HOMOCYSTINURIA: CLINICAL AND PATHOLOGICAL REVIEW OF TEN CASES.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Blood Chemical Analysis; Bone Diseases; Brain; Brain Diseases; Cardiovascular Diseases; Cerebrospinal Fluid; Child; Chromatography; Congenital Abnormalities; Eye Diseases; Facial Expression; Fatty Liver; Foot Diseases; Genetics, Medical; Homocystinuria; Humans; Hydro-Lyases; Infant; Intellectual Disability; Lens, Crystalline; Liver; Metabolism; Methionine; Urine | 1965 |
BLOOD AMMONIA IN RATS WITH EXPERIMENTAL LIVER DAMAGE.
Topics: Ammonia; Antimetabolites; Blood; Chemical and Drug Induced Liver Injury; Diet; Ethionine; Fatty Liver; Hepatitis; Hepatitis A; Methionine; Pathology; Pharmacology; Rats; Research; Toxicology | 1965 |
[FURTHER STUDIES ON THE PREVENTION OF THE ACUTE FATTY LIVER INDUCED BY ETHIONINE. 2. EFFECTS OF METHIONINE AND N-CARBOBENZOXY-L-GLUTAMYLCHOLINE UPON ESTERASE ACTION AND HISTOLOGICAL ASPECTS OF FAT IN ACUTE FATTY LIVER INDUCED BY ETHIONINE].
Topics: Amino Acids; Biomedical Research; Esterases; Ethionine; Fatty Liver; Methionine; Rats; Research; Toxicology | 1965 |
THE LIPOTROPIC ACTION OF COLD. 2. THE INFLUENCE OF COLD AND CHOLINE DEFICIENCY ON SERUM LIPIDS OF RATS AT DIFFERENT INTAKES OF DIETARY METHIONINE.
Topics: Cholesterol; Choline; Choline Deficiency; Cold Temperature; Diet; Fatty Liver; Glycerides; Lipids; Lipotropic Agents; Methionine; Phospholipids; Rats; Research; Vitamin B Deficiency | 1965 |
THE EFFECTS OF CHOLINE AND RELATED COMPOUNDS ON THE GROWTH AND DEVELOPMENT OF DROSOPHILA MELANOGASTER.
Topics: Amino Acids; Amino Alcohols; Ammonium Compounds; Animals; Betaine; Carnitine; Chemical Phenomena; Chemistry; Choline; Diet; Drosophila; Drosophila melanogaster; Fatty Liver; Folic Acid; Growth and Development; Meat; Metamorphosis, Biological; Methionine; Neurospora; Pharmacology; Poultry; Quaternary Ammonium Compounds; Rats; Research; Salts; Vitamin B Complex | 1965 |
Fatty liver of portal type: effects of choline, methionine, and vitamin B12.
Topics: Choline; Fatty Liver; Liver Diseases; Methionine; Vitamin B 12; Vitamin B Complex | 1955 |
[Relation between fatty liver due to cystine and methionine and glycine].
Topics: Cystine; Fabaceae; Fatty Liver; Glycine; Humans; Liver Diseases; Methionine | 1962 |
Rodent nutritional model of non-alcoholic steatohepatitis: species, strain and sex difference studies.
Topics: Alanine Transaminase; Animals; Choline Deficiency; Disease Models, Animal; Fatty Liver; Female; Lipid Peroxidation; Liver; Male; Malnutrition; Methionine; Mice; Mice, Inbred C57BL; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Sex Factors; Species Specificity | 2003 |
Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis.
Topics: Animals; Choline; Diet; Fatty Liver; Gene Expression; Hepatocytes; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Methionine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation | 2003 |
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance.
Topics: Alanine Transaminase; Animals; Blood Glucose; Choline Deficiency; Deficiency Diseases; Fasting; Fatty Liver; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Methionine; Mice; Mice, Inbred Strains | 2004 |
Sex differences in choline-deficient diet-induced steatohepatitis in mice.
Topics: Animal Feed; Animals; Apoptosis; Body Weight; Cell Differentiation; Choline Deficiency; Fatty Liver; Female; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Organ Size; Sex Factors; Transaminases; Triglycerides | 2004 |
[Effect of methionine and choline on the cholestero overload of the liver in experimental steatosis of the liver in the rat].
Topics: Animals; Choline; Fatty Liver; Liver; Methionine; Rats | 1950 |
Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model.
Topics: Alanine Transaminase; Animals; Choline Deficiency; Collagen Type I; Diet; Fatty Liver; Female; Hepatocytes; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred Strains; Mice, Knockout; Molecular Weight; Organ Size; Osteopontin; Oxidative Stress; Sialoglycoproteins; Triglycerides; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin.
Topics: Animals; Cell Line; Choline Deficiency; Deficiency Diseases; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Osteopontin; Receptors, Cell Surface; Receptors, Leptin; Sialoglycoproteins | 2004 |
Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice.
Topics: Animals; Cell Adhesion; Choline Deficiency; Deficiency Diseases; Diet; Dietary Fats; Fatty Liver; Fibrosis; Leukocytes; Lipid Metabolism; Lipid Peroxides; Liver; Liver Circulation; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Microcirculation; Microscopy, Electron; Oxidative Stress; Phagocytes; Vascular Patency | 2004 |
[Effect of lipotropic substances upon blood and liver lipoids in experimental fatty liver and in liver cirrhosis in man].
Topics: Choline; Fatty Liver; Lipotropic Agents; Liver; Liver Cirrhosis; Methionine | 1950 |
Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet.
Topics: Alanine Transaminase; Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Progression; Fatty Liver; Female; Glutathione; Hepatitis; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Pentoxifylline; Phosphodiesterase Inhibitors; RNA, Messenger; Triglycerides; Tumor Necrosis Factor-alpha | 2004 |
Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice.
Topics: Animals; Chemokine CCL2; Choline Deficiency; Collagen Type I; Curcumin; Cyclooxygenase 2; Deficiency Diseases; Diet; Enzyme Inhibitors; Fatty Liver; Female; Hepatitis; Inflammation Mediators; Intercellular Adhesion Molecule-1; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Severity of Illness Index; Transcription Factor AP-1 | 2004 |
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Cell Line; Choline; Cytochrome P-450 CYP2E1; DNA-Binding Proteins; Down-Regulation; Fatty Liver; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Glutathione Peroxidase; Glycogen Synthase Kinase 3; Hepatitis; Hepatocytes; Humans; Immunoprecipitation; Insulin; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Nerve Tissue Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; RNA; Serine; Signal Transduction; Subcellular Fractions; Time Factors; Transcription Factors; Tyrosine; Up-Regulation | 2005 |
Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methionine-choline-deficient diet.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Choline Deficiency; Cytochrome P-450 CYP2E1; Diet; Fatty Liver; Male; Methionine; Mice; Mice, Transgenic; Prealbumin | 2005 |
A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes.
Topics: Animals; Betaine; Disease Models, Animal; Ethanol; Fatty Liver; Hepatocytes; Male; Methionine; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine | 2005 |
Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice.
Topics: Animals; Apoptosis; Cell Adhesion Molecules; Choline Deficiency; Fatty Liver; Gene Expression Regulation; Kupffer Cells; Liver Cirrhosis, Experimental; Male; Methionine; Mice; Mice, Knockout; Mitochondria, Liver; Mutation; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2006 |
Metabolic profiling of livers and blood from obese Zucker rats.
Topics: Animals; Betaine; Energy Metabolism; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Fatty Liver; Glutathione; Glycolysis; Lipid Peroxidation; Liver; Magnetic Resonance Spectroscopy; Male; Methionine; Mitochondria; Obesity; Rats; Rats, Zucker; Reperfusion Injury; Triglycerides | 2006 |
NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis.
Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Inflammation Mediators; Intercellular Adhesion Molecule-1; Methionine; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NF-kappa B; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
JNK1 but not JNK2 promotes the development of steatohepatitis in mice.
Topics: Adiponectin; Alanine Transaminase; Animals; Apoptosis; Choline Deficiency; Enzyme Activation; Fatty Liver; Female; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Triglycerides | 2006 |
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biomarkers; Choline; Chromatography, High Pressure Liquid; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Heterozygote; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Severity of Illness Index; Up-Regulation | 2006 |
Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium.
Topics: Animals; Cell Line; Choline Deficiency; Culture Media; Fatty Liver; Hepatocytes; Methionine; Mice; Osteopontin; Phosphatidylinositol 3-Kinases; Sialoglycoproteins; Transaminases | 2006 |
Glutathione-enhancing agents protect against steatohepatitis in a dietary model.
Topics: Animals; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Food, Formulated; Inflammation; Lipotropic Agents; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Thiazoles; Transaminases | 2006 |
COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator.
Topics: Animals; Choline Deficiency; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet; Enzyme Induction; Fatty Liver; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-6; Lipogenesis; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; PPAR alpha; Tumor Necrosis Factor-alpha | 2006 |
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
Topics: Acyl-CoA Oxidase; Alanine Transaminase; Animals; Bezafibrate; Carnitine O-Palmitoyltransferase; Cholesterol, HDL; Choline; Diet; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Fatty Liver; Gene Expression; Interleukin-6; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; PPAR delta; RNA, Messenger; Thiazoles; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triglycerides | 2006 |
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
Topics: Allosteric Regulation; Animals; Carcinoma, Hepatocellular; Cell Line; Cystathionine beta-Synthase; Enzyme Stability; Fatty Liver; Gene Silencing; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Knockout; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine | 2006 |
Rodent nutritional model of steatohepatitis: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Triglycerides; Tumor Necrosis Factor-alpha | 2006 |
The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Constitutive Androstane Receptor; Diet; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Knockout; Organ Size; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Translocation, Genetic | 2007 |
Quantitative trait loci analysis of mice administered the methionine-choline deficient dietary model of experimental steatohepatitis.
Topics: Animals; Choline Deficiency; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Methionine; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Quantitative Trait Loci | 2006 |
Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Fatty Liver; Female; Hydroxyproline; Iron Overload; Lipid Peroxidation; Liver; Methionine; Organ Size; Rats; Rats, Inbred F344 | 2006 |
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.
Topics: Animals; Chemokine CCL2; Chemokine CCL4; Choline; Choline Deficiency; Cyclooxygenase 2; Diet; Disease Models, Animal; Fatty Liver; Female; Gene Expression Regulation; Hepatitis; Intercellular Adhesion Molecule-1; Liver; Macrophage Inflammatory Proteins; Membrane Glycoproteins; Methionine; Mice; Mice, Mutant Strains; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Oxidative Stress; RNA, Messenger; Tumor Necrosis Factor-alpha | 2007 |
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis.
Topics: Animal Feed; Animals; Choline; Collagen Type I; Collagen Type I, alpha 1 Chain; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Methionine; Obesity; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; Rats; Rats, Inbred OLETF; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones; Transforming Growth Factor beta; Up-Regulation | 2007 |
Choline cannot be replaced by propanolamine in mice.
Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Liver; Methionine; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Propanolamines; Triglycerides | 2007 |
Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet.
Topics: Animals; Biomarkers; Body Weight; Choline Deficiency; Diet; Dietary Fats; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fatty Liver; Hepatitis; Lipids; Liver; Male; Methionine; Mice; Mice, Obese; Oxidative Stress; Transaminases | 2007 |
Lipoprotein lipase activator ameliorates the severity of dietary steatohepatitis.
Topics: Animals; Benzamides; Cholesterol; Choline Deficiency; Cyclooxygenase 2; Diet; Enzyme Activation; Fatty Liver; Gene Expression; Hypolipidemic Agents; Intercellular Adhesion Molecule-1; Interleukin-6; Lipogenesis; Lipoprotein Lipase; Lipoproteins, HDL; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; PPAR gamma; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2007 |
The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population.
Topics: Adult; Alleles; Asian People; DNA Primers; Fatty Liver; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Japan; Male; Methionine; Middle Aged; Phosphatidylethanolamine N-Methyltransferase; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Valine | 2007 |
Preservation of steatotic livers: a comparison between cold storage and machine perfusion preservation.
Topics: Animals; Cold Temperature; Fatty Liver; Humans; Liver Function Tests; Liver Transplantation; Male; Methionine; Models, Animal; Organ Preservation; Perfusion; Rats; Rats, Wistar; Reperfusion; Tissue Donors | 2007 |
Protective effect of soy isoflavones and activity levels of plasma paraoxonase and arylesterase in the experimental nonalcoholic steatohepatitis model.
Topics: Animals; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Choline Deficiency; Disease Models, Animal; Fatty Liver; Glycine max; Hepatitis; Isoflavones; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methionine; Rats | 2007 |
CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.
Topics: Acute-Phase Reaction; Animals; Body Weight; CCAAT-Enhancer-Binding Protein-beta; Choline Deficiency; Cytochrome P-450 CYP2E1; Diet; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; Fatty Liver; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipase; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Transcription Factor CHOP; Tumor Necrosis Factor-alpha | 2007 |
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.
Topics: Adiponectin; Animal Feed; Animals; Blood Glucose; Choline; Cytochrome P-450 CYP2E1; Diacylglycerol O-Acyltransferase; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Hepatocytes; Insulin; Lipid Peroxidation; Liver Cirrhosis; Male; Methionine; Mice; Mice, Mutant Strains; Obesity; Oligoribonucleotides, Antisense; Oxidative Stress; Triglycerides; Tumor Necrosis Factor-alpha | 2007 |
Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Choline; Connective Tissue Growth Factor; Fatty Liver; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Liver Cirrhosis; Male; Methionine; Oxidative Stress; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2007 |
Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Choline; Choline Deficiency; Diet; Fatty Acids, Unsaturated; Fatty Liver; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C3H | 2007 |
Role of adipocytokines in hepatic fibrogenesis.
Topics: Adiponectin; Animals; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Kupffer Cells; Leptin; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Oxidative Stress; Transforming Growth Factor beta1; Up-Regulation | 2007 |
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis.
Topics: Animals; Choline Deficiency; Clodronic Acid; Collagen Type I; Collagen Type I, alpha 1 Chain; Diet; Endotoxemia; Fatty Liver; Hepatitis, Animal; Kupffer Cells; Lymphotoxin-alpha; Methionine; Mice; Mice, Mutant Strains; PPAR alpha; Signal Transduction; Toll-Like Receptor 4; Triglycerides | 2007 |
Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Topics: Adult; Aged; Alanine Transaminase; Animals; Aspartate Aminotransferases; Choline Deficiency; Clorgyline; Disease Models, Animal; Fatty Liver; Female; Hepatitis; Humans; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Severity of Illness Index; Tryptophan Hydroxylase; Up-Regulation | 2007 |
Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis.
Topics: Animals; Choline; Cytochrome P-450 CYP2E1; Fatty Liver; Hepatitis; Liver; Male; Methionine; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Thioacetamide | 2003 |
Methionine deficiency and hepatic injury in a dietary steatohepatitis model.
Topics: Animals; Choline Deficiency; Fatty Liver; Gene Expression; Hepatitis, Animal; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley | 2008 |
Not all models of fatty liver are created equal: understanding mechanisms of steatosis development is important.
Topics: Animals; Choline Deficiency; Disease Models, Animal; Fatty Liver; Fatty Liver, Alcoholic; Humans; Methionine; Rats | 2007 |
Essential pathogenic and metabolic differences in steatosis induced by choline or methione-choline deficient diets in a rat model.
Topics: Animals; Choline Deficiency; Disease Models, Animal; Fatty Liver; Insulin; Lipids; Liver; Male; Methionine; Oxidative Stress; Rats; Rats, Wistar | 2007 |
Genes of the antioxidant response undergo upregulation in a rodent model of nonalcoholic steatohepatitis.
Topics: Animal Feed; Animals; Antioxidants; Catalytic Domain; Choline Deficiency; Diet; Disease Models, Animal; Epoxide Hydrolases; Fatty Liver; Glutamate-Cysteine Ligase; Heme Oxygenase (Decyclizing); Male; Methionine; NAD(P)H Dehydrogenase (Quinone); Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Up-Regulation | 2007 |
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
Topics: Animals; Body Weight; Disease Models, Animal; Ethanol; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Linear Models; Liver; Liver Diseases, Alcoholic; Male; Methionine; Necrosis; Oxidative Stress; S-Adenosylmethionine; Swine; Swine, Miniature | 2007 |
Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.
Topics: Animals; Choline Deficiency; Dietary Fats, Unsaturated; Disease Models, Animal; Down-Regulation; Fatty Acids; Fatty Acids, Omega-3; Fatty Liver; Female; Fish Oils; Gene Expression; Lipid Peroxides; Lipogenesis; Lipolysis; Liver; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha | 2008 |
Interstrain differences in susceptibility to non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Body Weight; Choline Deficiency; Disease Models, Animal; Disease Susceptibility; Fatty Liver; Gene Expression; Lipid Metabolism; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Organ Size; RNA, Messenger; Species Specificity | 2008 |
The influence of methionine, selenomethionine, and vitamin E on liver metabolic pathways and steatosis in high-cholesterol fed rabbits.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol; Cholesterol, Dietary; Fatty Liver; Fructose-Bisphosphate Aldolase; Glutamate Dehydrogenase; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Methionine; Rabbits; Selenomethionine; Triglycerides; Vitamin E | 2007 |
Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse.
Topics: Animals; Apoptosis; Choline Deficiency; Constitutive Androstane Receptor; Fatty Acids; Fatty Liver; Inflammation; Leukotriene B4; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha; Pyridines; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2007 |
Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet.
Topics: Adaptation, Physiological; Animal Feed; Animals; Choline; Choline Deficiency; Energy Metabolism; Fatty Liver; Hepatitis; Interleukin-6; Male; Malnutrition; Methionine; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2008 |
The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Ethanol; Fatty Liver; Fatty Liver, Alcoholic; Gene Expression; Liver; Liver Function Tests; Male; Methionine; Mice; Mice, Inbred Strains; Organ Size; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Effects of rosiglitazone on methionine-choline deficient diet-induced nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline; Diet; Disease Models, Animal; Fatty Liver; Liver; Methionine; Mice; Mitochondria, Liver; Rosiglitazone; Thiazolidinediones | 2007 |
The treatment with antibody of TNF-alpha reduces the inflammation, necrosis and fibrosis in the non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet.
Topics: Actins; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Aspartate Aminotransferases; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Hepatitis; Infliximab; Injections, Intraperitoneal; Liver; Liver Cirrhosis; Male; Malondialdehyde; Methionine; Necrosis; Rats; Time Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2008 |
Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo.
Topics: Animals; Capsules; Cells, Cultured; Choline Deficiency; Fatty Liver; Flavonoids; Glucosides; Hepatocytes; Herbal Medicine; Hydrolyzable Tannins; Male; Methionine; Mice; Mice, Inbred C57BL; Phyllanthus; Polysaccharides; Rats; Rats, Wistar | 2008 |
Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet.
Topics: Adipose Tissue; Animals; Body Weight; Choline Deficiency; Chromatography, Liquid; Dietary Fats; Fatty Liver; Lipids; Lipoproteins, VLDL; Liver; Methionine; Mice; Models, Biological; Organ Size; Polymerase Chain Reaction; RNA; Skin; Viscera | 2008 |
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.
Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated; Glutathione; Hepatitis; Homeostasis; Lipid Metabolism; Liver; Methionine; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; S-Adenosylmethionine | 2008 |
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
Topics: Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Glycine N-Methyltransferase; Histones; Janus Kinases; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice; Mice, Knockout; Promoter Regions, Genetic; ras Proteins; S-Adenosylmethionine; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Transaminases; Tumor Suppressor Proteins | 2008 |
Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Carnosine; Choline Deficiency; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hepatic Stellate Cells; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Methionine; Mice; Mice, Inbred C57BL; Organometallic Compounds; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha; Zinc Compounds | 2008 |
Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Ethanol; Fatty Liver; Fatty Liver, Alcoholic; Folic Acid; Gene Expression; Homocysteine; Humans; Methionine; Mice; Mice, Transgenic; Recombinant Proteins | 2008 |
Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty Acids; Fatty Liver; Imidazoles; Insulin Resistance; Liver Cirrhosis, Experimental; Male; Methionine; Oxidative Stress; Rats; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2008 |
Effects of L-asparagine and related compounds on the hepatic fatty infiltration and necrosis induced by ethionine and carbon tetrachloride.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Tetrachloride; Chromatography, Gas; Ethionine; Fatty Acids; Fatty Liver; Female; Glutamine; Glycerides; Ketoglutaric Acids; Liver; Methionine; Necrosis; Rats; Triglycerides | 1967 |
Vitamin B12, choline and related substances in dietary hepatic injury in rats.
Topics: Amino Acids; Animals; Body Weight; Choline; Cystine; Diet; Fatty Liver; Growth; Homocystine; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Rats; Vitamin B 12 | 1967 |
The influence of testosterone on the induction of fatty liver by methionine deficiency.
Topics: Amino Acids; Animals; Castration; Choline; Deficiency Diseases; Diet; Fatty Liver; Female; Glutamates; Lipid Metabolism; Liver; Liver Glycogen; Male; Methionine; Organ Size; Proteins; Rats; Testosterone | 1967 |
Lipid transport in experimental dietary hepatic injury in rats.
Topics: Animals; Biological Transport; Cholesterol; Choline; Dietary Proteins; Fats, Unsaturated; Fatty Liver; Homocystine; Lipid Metabolism; Lipoproteins; Liver; Male; Methionine; Phospholipids; Rats; Vitamin B 12 | 1967 |
Fatty liver due to disproportionally added methionine to a low soybean diet and lipotropic action of phosphatides in rats.
Topics: Animals; Apolipoproteins; Biological Transport; Cholesterol; Fatty Liver; Glycine max; Insulin; Lipid Metabolism; Methionine; Phosphatidylcholines; Phospholipids; Plant Proteins, Dietary; Rats; Triglycerides | 1980 |
Comparative effects of S-methylmethionine (vitamin U) and methionine on choline-deficient fatty liver in rats.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Fatty Liver; Male; Methionine; Organ Size; Rats; Time Factors; Vitamin U; Vitamins | 1980 |
In vivo microscopic observation of fatty liver grafts after reperfusion.
Topics: Animals; Choline Deficiency; Endothelium, Vascular; Fatty Liver; Graft Survival; Liver; Liver Circulation; Liver Transplantation; Methionine; Microcirculation; Organ Preservation; Rats; Rats, Inbred ACI; Reperfusion; Time Factors; Transplantation, Isogeneic | 1994 |
A rat fatty liver transplant model.
Topics: Animals; Choline Deficiency; Chromatography, Gas; Diet; Disease Models, Animal; Fatty Liver; Graft Survival; Lipids; Liver; Liver Diseases; Liver Transplantation; Male; Methionine; Necrosis; Postoperative Period; Rats; Rats, Inbred ACI; Time Factors | 1993 |
Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats.
Topics: Acetophenones; Animals; Aspirin; Choline; Choline Deficiency; Cyclooxygenase Inhibitors; Fatty Liver; gamma-Glutamyltransferase; Glutathione Transferase; Lipoxygenase Inhibitors; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Masoprocol; Methionine; Oxidative Stress; Phospholipases A; Phospholipases A2; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Time Factors | 1996 |
The effects of N-acetylcysteine and anti-intercellular adhesion molecule-1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet.
Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Antibodies, Monoclonal; Aspartate Aminotransferases; Bile; Choline Deficiency; Fatty Liver; In Vitro Techniques; Intercellular Adhesion Molecule-1; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Methionine; Microscopy, Electron; Neutrophils; Perfusion; Rats; Rats, Wistar; Reperfusion Injury | 1997 |
S-adenosyl-L-methionine attenuates ischemia-reperfusion injury of steatotic livers.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Choline Deficiency; Fatty Liver; Glutathione; Glutathione Disulfide; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Methionine; Mitochondria, Liver; Rats; Rats, Wistar; Reperfusion Injury; S-Adenosylmethionine | 1998 |
N-acetylcysteine and anti-ICAM-1 monoclonal antibody reduce ischemia-reperfusion injury of the steatotic rat liver.
Topics: Acetylcysteine; Adenosine; Allopurinol; Animals; Antibodies, Monoclonal; Choline Deficiency; Fatty Liver; Glutathione; Insulin; Intercellular Adhesion Molecule-1; Ischemia; Liver; Male; Methionine; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury | 1998 |
Does steatohepatitis impair liver regeneration? A study in a dietary model of non-alcoholic steatohepatitis in rats.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Choline Deficiency; Fatty Liver; Follow-Up Studies; Hepatectomy; Hepatitis, Animal; Liver Regeneration; Male; Methionine; Rats; Rats, Wistar | 1999 |
Effects of fat and methionine hydroxy analog on prevention or alleviation of fatty liver induced by feed restriction.
Topics: Animals; Blood Glucose; Cattle; Dietary Fats; Energy Metabolism; Fatty Acids, Nonesterified; Fatty Liver; Female; Food Deprivation; Hydroxylation; Liver; Methionine; Pregnancy; Triglycerides | 1999 |
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Topics: Animals; Catalysis; Choline Deficiency; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fatty Liver; Female; Gene Expression; Hepatitis; Lipid Peroxidation; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microsomes; Mixed Function Oxygenases; Weight Loss | 2000 |
Dietary cystine and liver triacylglycerols in rats: effects of dietary lysine and threonine.
Topics: Amino Acids; Animals; Cystine; Fatty Liver; Glutens; Liver; Lysine; Male; Methionine; Organ Size; Rats; Rats, Wistar; Threonine; Triglycerides; Triticum | 1998 |
Steatosis is not sufficient to cause an impaired regenerative response after partial hepatectomy in rats.
Topics: Animal Feed; Animals; Blotting, Western; Bromodeoxyuridine; CDC2-CDC28 Kinases; Cholesterol; Choline; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Disease Models, Animal; Fatty Liver; Hepatectomy; Liver; Liver Regeneration; Male; Methionine; Organ Size; Orotic Acid; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Rats, Zucker; Triglycerides | 2002 |
Sex difference in the development of fatty liver by orotic acid.
Topics: Acetates; Animals; Fatty Liver; Female; Lipoproteins, LDL; Liver; Male; Methionine; Orotic Acid; Phosphatidylcholines; Proteins; Rats; Sex Factors | 1975 |
[Results of oral methionine loads in normal subjects and patients with liver diseases using an analyzer short program].
Topics: Adolescent; Adult; Amino Acids; Chromatography, Gas; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Diseases; Male; Methionine; Middle Aged; Time Factors | 1977 |
Uptake of adenosylmethionine and related sulfur compounds by isolated rat liver.
Topics: Biological Transport; Dinitrophenols; Fatty Liver; Kinetics; Liver; Methionine; S-Adenosylmethionine | 1978 |
The effect of methionine, thiouracil, dienestrol diacetate and thyroprotein on the development and prevention of fatty liver in pullets.
Topics: Adipose Tissue; Animal Feed; Animals; Caseins; Chickens; Dienestrol; Eggs; Fatty Liver; Female; Hematoma; Hemorrhage; Iodoproteins; Lipid Metabolism; Liver; Liver Diseases; Methionine; Phenols; Phosphorus; Poultry Diseases; Syndrome; Thiouracil | 1975 |
Fatty liver induced by methionine supplementation of low protein diet: effect of inositol supply.
Topics: Animals; Dietary Proteins; Fatty Liver; Inositol; Methionine; Rats | 1991 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
A comparison of the response of woodchucks and rats to variations in dietary lipotrope and protein content.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Fatty Liver; Folic Acid Deficiency; Male; Marmota; Methionine; Protein Deficiency; Rats; Rats, Inbred F344; Sciuridae; Species Specificity; Vitamin B 12 Deficiency | 1986 |
Effect of dietary protein and amino acids in a choline-deficient diet on lipid accumulation in rat liver.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Caseins; Choline Deficiency; Depression, Chemical; Diet Therapy; Dietary Proteins; Fatty Liver; Female; Glutamates; Lipid Metabolism; Lipotropic Agents; Liver; Metabolism; Methionine; Ovalbumin; Rats; Serine | 1971 |
Animal model: fatty liver and cirrhosis in lipotrope-deficient male rats.
Topics: Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Models, Animal; Fatty Liver; Humans; Lipotropic Agents; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Rats; Vitamin B 12 Deficiency | 1973 |
Fatty liver and kidney syndrome in chicks. Effects on liver and kidney of diets causing the syndrome.
Topics: Animals; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Body Weight; Calcium, Dietary; Chickens; Cystine; Diet; Dietary Proteins; Ethers; Fatty Liver; Female; Kidney; Kidney Diseases; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Poultry Diseases | 1974 |
[Hepatic steatosis and cholesterolemia in the domestic duckling in the course of protein malnutrition on a rice diet].
Topics: Animals; Arginine; Deficiency Diseases; Fatty Liver; Glutamine; Glycine; Growth; Histidine; Hypercholesterolemia; Isoleucine; Leucine; Lysine; Methionine; Oryza; Phenylalanine; Poultry Diseases; Protein Deficiency; Threonine; Tryptophan; Valine | 1965 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
Effect of methionine on liver lipid content and lipid metabolism of rats fed a protein-free diet.
Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Proteins; Body Composition; Body Weight; Carbon Dioxide; Carbon Isotopes; Dietary Carbohydrates; Dietary Fats; Fatty Liver; Glucose; Lipid Metabolism; Lipoproteins, LDL; Liver; Male; Methionine; Nitrogen; Protein Deficiency; Rats; Sucrose; Threonine; Time Factors | 1973 |
Effect of amino acid supplement on liver lipid content and lipid metabolism of rats fed a nonprotein diet.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Biological Transport; Body Weight; Drug Synergism; Fatty Acids; Fatty Liver; Female; Lipid Metabolism; Lipoproteins; Lipoproteins, LDL; Liver; Male; Methionine; Phospholipids; Polyethylene Glycols; Protein Deficiency; Rats; Sex Factors; Threonine | 1974 |
Involvement of biotin in the fatty liver and kidney syndrome of broilers.
Topics: Animal Feed; Animals; Biotin; Diet; Fatty Liver; Housing, Animal; Kidney Diseases; Lysine; Methionine; Poultry Diseases; Syndrome; Triticum; Tryptophan; Vitamins | 1974 |
Effect of diet on fatty liver-hemorrhagic syndrome incidence in laying chickens.
Topics: Animals; Body Weight; Chickens; Choline; Cobalt; Diet; Fatty Liver; Female; Hemorrhage; Inositol; Lipids; Liver; Methionine; Poultry Diseases; Selenium; Syndrome; Vitamin B 12; Vitamin E | 1972 |
Effect of various carbohydrates in a repletion diet after protein depletion on liver lipid content of rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Caseins; Diet Therapy; Dietary Carbohydrates; Dietary Proteins; Fatty Liver; Fructose; Glucose; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Polysaccharides; Protein Deficiency; Rats; Starch; Sucrose | 1973 |
Reply to Silen's letter. "Pancreatectomy and liver damage" (January 1973).
Topics: Animals; Dogs; Fatty Liver; Gastric Juice; Methionine; Pancreatectomy; Pancreatin | 1973 |
Involvement of diet in fatty liver and kidney syndrome in broiler chickens.
Topics: Animal Feed; Animals; Chickens; Choline; Diet; Edible Grain; Fatty Liver; Kidney; Kidney Diseases; Lipid Metabolism; Liver; Methionine; Poultry Diseases; Selenium; Syndrome; Vitamin B 12 | 1973 |
Response of adult rats to deficiencies of different essential amino acids.
Topics: Amino Acids; Animals; Body Weight; Brain; Deficiency Diseases; Diet; Fatty Liver; Female; Hematocrit; Hemoglobins; Kidney; Lactalbumin; Liver; Lysine; Methionine; Nitrogen; Organ Size; Proteins; Rats; Threonine | 1974 |
[Clinical treatment of acute and chronic liver diseases].
Topics: Acute Disease; Choline; Chronic Disease; Fatty Liver; Hepatitis; Humans; Liver Diseases; Male; Methionine; Middle Aged | 1972 |
Pre-erythrocytic rodent malaria, Plasmodium berghei--prevention of development in the ethionine fatty liver.
Topics: Adenosine; Animals; Erythrocytes; Ethionine; Fatty Liver; Female; Injections, Intraperitoneal; Liver; Malaria; Methionine; Methods; Plasmodium; Rats | 1972 |
[Various effects of SAM dependent transmethylations in hepatology].
Topics: Adenosine; Biopsy; Chronic Disease; Fatty Liver; Hepatitis; Humans; Injections, Intraperitoneal; Lipid Metabolism; Liver Cirrhosis; Liver Diseases; Liver Glycogen; Methionine; Methylation; S-Adenosylmethionine | 1972 |
Pancreatectomy and liver damage: effects on humoral gastric secretion in dogs.
Topics: Animals; Dogs; Fatty Liver; Female; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Methionine; Pancreatectomy; Pancreatin; Stimulation, Chemical; Time Factors | 1972 |
Influence of insulin, hydrocortisone and thyroxine on fatty liver of rats fed a low casein diet supplemented with methionine.
Topics: Adrenal Glands; Adrenalectomy; Animal Nutritional Physiological Phenomena; Animals; Blood Proteins; Body Weight; Caseins; Depression, Chemical; Diabetes Mellitus, Experimental; Dietary Proteins; Fatty Liver; Female; Glucocorticoids; Hydrocortisone; Insulin; Insulin Antibodies; Iodine; Lipid Metabolism; Liver; Methionine; Pancreas; Protein Binding; Protein Deficiency; Rats; Stimulation, Chemical; Thyroid Gland; Thyroidectomy; Thyroxine | 1971 |
Liver steatosis of force-fed geese as influenced by the protein level of the diet.
Topics: Animals; Dietary Proteins; Fatty Liver; Female; Geese; Liver; Male; Meat; Methionine; Organ Size | 1971 |
Kipid metabolism in the rats with fatty liver caused by low protein diet and effects of the oral administration of L-methionine, L-cysteine, pantethine and calcium pantothenate upon it.
Topics: Animals; Body Weight; Calcium; Cholesterol; Chromatography, Gas; Coenzyme A; Cysteine; Dietary Fats; Fatty Acids; Fatty Liver; Lipid Metabolism; Lipids; Liver; Male; Methionine; Organ Size; Pantothenic Acid; Phospholipids; Rats; Time Factors; Triglycerides | 1969 |
Early changes in livers of rats fed choline-deficient diets at four levels of protein.
Topics: Alkaline Phosphatase; Animals; Blood Proteins; Body Weight; Choline; Cystine; Diet; Dietary Proteins; DNA; Endoplasmic Reticulum; Fatty Liver; Hypertrophy; L-Lactate Dehydrogenase; Lipids; Liver; Liver Cirrhosis, Experimental; Male; Methionine; Microscopy, Electron; Mitochondria, Liver; Organ Size; Rats; RNA; Transaminases | 1969 |
Pathogenesis of methionine-induced toxicity.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Fatty Liver; Female; Guinea Pigs; Hypoglycemia; Hypothermia; Kidney; Liver; Liver Glycogen; Male; Methionine; Nucleosides; Rats; Spasm; Stereoisomerism | 1970 |
[Liver function tests with methionine-Se 75 in diabetics].
Topics: Diabetes Complications; Diabetes Mellitus; Fatty Liver; Hepatomegaly; Humans; Liver; Liver Function Tests; Methionine; Selenium | 1970 |
Modification of the hepatotoxic action of neptunium-237 in the rat.
Topics: Adenine; Adenosine Triphosphate; Adrenalectomy; Alanine Transaminase; Animals; Antioxidants; Cresols; Estradiol; Fatty Liver; Female; Glucose; Hypophysectomy; Isocitrate Dehydrogenase; Liver; Male; Methionine; Neptunium; Nicotinic Acids; Rats; Testosterone | 1971 |
On the ethionine-induced inhibition of protein synthesis in male and female rats--lack of effect on intestinal mucosa.
Topics: Animals; Blood Proteins; Carbon Isotopes; Depression, Chemical; Dietary Fats; Ethionine; Fatty Liver; Female; Intestinal Mucosa; Jejunum; Leucine; Lipoproteins; Liver; Male; Methionine; Protein Biosynthesis; Rats; Sex; Triglycerides; Tritium; Ultracentrifugation; Zea mays | 1968 |
Methionine-responsive liver damage in young pigs fed a diet low in protien and vitamin E.
Topics: Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Choline; Diet; Fatty Liver; Female; Lipid Metabolism; Liver; Liver Diseases; Male; Methionine; Necrosis; Protein Deficiency; Selenium; Swine; Time Factors; Vitamin E; Vitamin E Deficiency | 1968 |
The induction of liver cirrhosis in rats by purified amino acid diets.
Topics: Amino Acids; Animals; Body Weight; Cholesterol; Choline Deficiency; Deficiency Diseases; Diet; Dietary Proteins; DNA; Fatty Liver; Lipids; Liver; Liver Cirrhosis; Male; Methionine; Rats; Thymidine; Triglycerides; Tritium; Vitamin B 12 Deficiency | 1969 |
[On methylation processes in metabolism].
Topics: Biochemical Phenomena; Biochemistry; Choline; Dietary Fats; Epinephrine; Fatty Liver; Humans; Mescaline; Metabolism; Methionine; Methylation; Norepinephrine; Phenethylamines; Phosphatidylcholines; Schizophrenia | 1969 |
Studies on phospholipid metabolism in choline deficient fatty liver.
Topics: Animals; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids; Fatty Liver; Female; Male; Methionine; Methylation; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Proteins; Rats | 1969 |
Effect of dl-ethionine and naturally occurring amino acids on adrenal necrosis induced by 7,12-dimethyl-benz [alpha]anthracene and its 7-hydroxymethyl derivative in female Sprague-Dawley rats.
Topics: Adrenal Gland Diseases; Amino Acids; Animals; Arginine; Benz(a)Anthracenes; Ethionine; Fatty Liver; Female; Glycine; Liver; Methionine; Necrosis; Protein Biosynthesis; Rats | 1969 |
Influence of ethionine on choline-deficiency fatty liver.
Topics: Alcohol Oxidoreductases; Animals; Body Weight; Carbon Isotopes; Choline Deficiency; Depression, Chemical; Ethionine; Fasting; Fatty Liver; Female; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Protein Biosynthesis; Proteins; Rats; Time Factors | 1969 |
Metabolism of phosphorylcholine and lecithin in normal and choline-deficient rats.
Topics: Animals; Carbon Isotopes; Choline; Choline Deficiency; Fatty Liver; Lipid Metabolism; Liver; Male; Methionine; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Rats | 1969 |
[Considerations on the therapy of hepatic steatosis].
Topics: Adult; Aged; Alcoholism; Choline; Colitis, Ulcerative; Diabetes Complications; Fatty Liver; Gout; Hepatitis A; Humans; Inositol; Methionine; Middle Aged; Vitamin B Complex | 1969 |
Alterations in phospholipid metabolism induced by ethanol administration.
Topics: Alkylation; Animals; Choline; Chromatography, Thin Layer; Ethanol; Fatty Liver; Formates; In Vitro Techniques; Liver; Methionine; Phosphatidylcholines; Phospholipids; Rats; Serine | 1965 |
Choline metabolism in normal and choline-deficient rats of different ages.
Topics: Aging; Animals; Body Weight; Choline; Choline Deficiency; Fatty Liver; Hemorrhage; Kidney; Liver; Methionine; Rats; Vitamin B Deficiency | 1965 |
Environmental temperature and choline requirements in rats. II. Choline and methionine requirements for lipotropic activity.
Topics: Animals; Choline; Choline Deficiency; Deficiency Diseases; Fatty Liver; Lipid Metabolism; Liver; Methionine; Rats; Temperature | 1966 |
Study of agents for the prevention of the fatty liver produced by prolonged alcohol intake.
Topics: Alcohol Deterrents; Alcoholism; Animals; Antioxidants; Choline; Diet; Fatty Liver; Glycerides; Humans; Methionine; Rats | 1966 |