Page last updated: 2024-08-17

methionine and Insulin Sensitivity

methionine has been researched along with Insulin Sensitivity in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.17)	18.7374
1990's	6 (9.52)	18.2507
2000's	7 (11.11)	29.6817
2010's	35 (55.56)	24.3611
2020's	13 (20.63)	2.80

Authors

Authors	Studies
Allawadhi, P; Bhatti, JS; Gaddam, RR; Jawalekar, SS; Khurana, A; Navik, U; Sheth, VG; Tikoo, K	1
Fang, H; Forney, LA; Gettys, TW; Stone, KP; Wanders, D	2
Chen, H; Li, C; Liu, X; Wang, P; Wu, C; Yang, X; Yang, Y; Yao, S; Yin, R; Yu, M; Zhou, B	1
Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A	1
Akhlaghi, M; Asadi, A; Lotfi, K; Mirzaei, S; Poursalehi, D; Saneei, P	1
Andreadis, ST; Breed, K; Choudhury, D; Ikhapoh, I; Kulczyk, J; Mohamed, MA; Personius, K; Rajabian, N; Saha, S; Seldeen, K; Shahini, A; Shahini, S; Stablewski, A; Thiyagarajan, R; Troen, BR; Udin, SB	1
Cheng, X; Feng, C; Ge, Y; Jiang, Y; Le, G; Li, B; Shi, Y; Tang, X; Wu, G; Zhu, J	1
Ding, P; Li, H; Sun, J; Weng, L; Xiang, W; Yang, Y; Ye, Z; Zeng, C	1
Deng, D; Hirano, E; Igarashi, K; Kaku, T; Lim, HS; Miyai, H; Nakamura, J; Shindo, T; Sugimoto, K; Toledo, A; Tone, T; Yamauchi, A	1
Hu, L; Ma, Q; Meng, Q; Shan, A; Shao, C; Sun, Y; Zhou, X; Zhu, J	1
Arola, J; Hakkarainen, A; Juuti, A; Lehtimäki, TE; Luukkonen, PK; Orho-Melander, M; Penttilä, AK; Qadri, S; Sammalkorpi, H; Yki-Järvinen, H	1
Anassori, E; Asri-Rezaei, S; Khalilvandi-Behroozyar, H; Sadegzadeh-Sadat, M	1
Badiali, S; Baselli, GA; Bassani, GA; Dongiovanni, P; Facciotti, F; Fargion, S; Gatti, S; Maggioni, M; Meroni, M; Pietrelli, A; Rametta, R; Trunzo, V; Valenti, L	1
De Blasio, MJ; Gatford, KL; Harland, ML; Owens, JA; Sulaiman, SA	1
Li, Y; Su, W; Wang, F; Wang, T; Ying, Z; Zhang, H; Zhang, L; Zhou, L	1
Forney, LA; Gettys, TW; Ntambi, JM; Stone, KP; Wanders, D	1
Forney, LA; Gettys, TW; Stone, KP; Wanders, D	1
Chen, S; Gao, J; Han, H; Li, T; Li, Y; Liu, G; Ren, W; Woo Kim, S; Wu, X; Yin, J; Yin, Y	1
Feige, K; Huber, K; Kenéz, Á; Warnken, T	1
Cho, S; Park, KW; Yang, J	1
Chung, S; Kim, Y; Natarajan, SK	1
Ge, X; Li, Y; Su, W; Wang, T; Ying, Z; Zhang, H; Zhang, L; Zhou, L	1
Boudreau, A; Feng, D; Gettys, TW; Ghosh, S; Hasek, BE; Hulver, M; Laque, A; Pessin, JE; Shin, J; Stewart, LK; Stone, KP; Van, NT; Wanders, D	1
Angus, PW; Forbes, JM; Goodwin, M; Herath, CB; Jia, Z; Leung, C; Mak, KY; Watt, MJ	1
Bykowska, AS; Delibegovic, M; Gettys, TW; Grant, L; Król, E; Lees, EK; Mody, N; Moncur, E; Shearer, K; Wyse, C	1
Cortez, CC; Gettys, TW; Orgeron, M; Stone, KP; Wanders, D	1
Delibegovic, M; Gettys, TW; Krol, E; Lees, EK; Mody, N; Shearer, K	1
Fischman, AJ; Kaneki, M; Kramer, J; Martyn, JA; Nakazawa, H; Tanaka, T; Tompkins, RG; Yamada, M; Yu, YM	1
Baker, M; Burk, DH; Cortez, CC; Gettys, TW; Mendoza, T; Mynatt, RL; Stone, KP; Van, NT; Wanders, D	1
Gokturk, HS; Kebapcilar, L; Korkmaz, H; Schmidt, WE; Unler, GK	1
El-Sabagh, M; Fukumori, R; Hasegawa, Y; Kangawa, K; Kobayashi, H; Kojima, M; Kushibiki, S; Moriya, N; Nagao, Y; Obitsu, T; Shingu, H; Sugino, T; Taniguchi, K; Yamaji, K	1
Ben Ya'acov, A; Ilan, Y; Khoury, T; Shabat, Y; Snir, R; Zolotarovya, L	1
Calderon, LF; Gettys, TW; Scherer, PE; Spurgin, SB; Stone, KP; Wanders, D	1
He, L; Wan, D; Wu, G; Wu, X; Yang, H; Yao, K; Yin, Y; Zhou, X	1
Georgescu, C; Kim, G; Levine, RL; Liu, C; Richardson, A; Salmon, AB; Wren, JD	1
Burk, DH; Forney, LA; Gettys, TW; Pierse, A; Stone, KP; Wanders, D	1
Kalhan, SC	1
Bidzińska-Speichert, B; Lenarcik, A; Tworowska-Bardzińska, U	1
Bachmair, EM; Boekschoten, MV; Brennan, L; Coort, SL; Daniel, H; Evelo, C; Gibney, MJ; Keijer, J; Kleemann, R; McLoughlin, GA; Muller, M; Roos, Bd; Rubio-Aliaga, I; Sailer, M; van Erk, M; van Schothorst, EM	1
Boudreau, A; Cefalu, WT; Gettys, TW; Greenway, FL; Hill, KL; Johnson, WD; Krajcik, RA; Orentreich, N; Perrone, CE; Plaisance, EP	1
Liu, WH; Liu, WJ; Ma, LQ; Zhang, KQ; Zhou, W; Zou, CG	1
Bennett, C; Dasarathy, S; Duenas, C; Edmison, J; Gruca, LL; Kalhan, SC; Lopez, R; Marczewski, S	1
Li, D; Lun, YZ; Zhou, SS; Zhou, YM	1
Bucchieri, F; Bugianesi, E; Galvano, F; Li Volti, G; Mangiameli, A; Marino Gammazza, A; Marino, A; Parola, M; Paternostro, C; Salamone, F; Tibullo, D	1
Adams, SH	1
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Tsai, TH; Yang, YY	1
Malloy, VL; Orentreich, DS; Orentreich, N; Perrone, CE	1
Ables, GP; Orentreich, D; Orentreich, N; Perrone, CE	1
Green, RM; Rinella, ME	1
Brosnan, JT; Brosnan, ME; Hall, B; Ratnam, S; Wijekoon, EP; Zeisel, SH	1
Akahori, H; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa, N; Misu, H; Nakanuma, Y; Ota, T; Sakurai, M; Takamura, T; Uno, M; Zen, Y	1
Barve, S; Cave, M; Deaciuc, I; Joshi-Barve, S; McClain, C; Mendez, C; Song, Z	1
Allegrucci, C; Bispham, J; Craigon, J; Gardner, DS; Huntley, JF; Lea, RG; Maloney, CA; McEvoy, TG; Rees, WD; Sebastian, S; Sinclair, KD; Singh, R; Thurston, A; Young, LE	1
Ando, H; Ishikura, K; Kaneko, S; Kita, Y; Kurita, S; Matsuzawa-Nagata, N; Misu, H; Nabemoto, S; Nakanuma, Y; Ota, T; Takamura, T; Uno, M; Zen, Y	1
Accili, D; al-Gazali, LI; Hone, J; Lestringant, G; Orban, T; Taylor, SI	1
Kielkopf-Renner, S; Krans, HM; Kuipers, A; Maassen, JA; Möller, W; van der Vorm, ER	1
Müller, G; Wied, S	1
Grobbee, DE; Hart, LM; Heine, RJ; Maassen, JA; Stolk, RP; van der Does, FE	1
Clausen, JO; Echwald, SM; Hansen, L; Hansen, T; Pedersen, O; Rasmussen, SK; Urhammer, SA	1
Cama, A; de la Luz Sierra, M; Gorden, P; Imperato-McGinley, J; Kadowaki, T; Ottini, L; Taylor, SI	1
Hedo, JA; Moncada, VY; Serrano-Rios, M; Taylor, SI	1
Hedo, JA; Moncada, VY; Taylor, SI	1

Reviews

9 review(s) available for methionine and Insulin Sensitivity

Article	Year
Methionine as a double-edged sword in health and disease: Current perspective and future challenges. Ageing research reviews, 2021, Volume: 72 Topics: Body Weight; Diet; Humans; Insulin Resistance; Longevity; Methionine	2021
Nutritional Regulation of Hepatic FGF21 by Dietary Restriction of Methionine. Frontiers in endocrinology, 2021, Volume: 12 Topics: Animals; Diet, Protein-Restricted; Fibroblast Growth Factors; Humans; Insulin Resistance; Liver; Methionine	2021
The Origins, Evolution, and Future of Dietary Methionine Restriction. Annual review of nutrition, 2022, 08-22, Volume: 42 Topics: Animals; Diet; Energy Intake; Energy Metabolism; Fibroblast Growth Factors; Humans; Insulin Resistance; Liver; Methionine; Rats	2022
Sensing and signaling mechanisms linking dietary methionine restriction to the behavioral and physiological components of the response. Frontiers in neuroendocrinology, 2018, Volume: 51 Topics: Animals; Diet; Fibroblast Growth Factors; Insulin Resistance; Lipid Metabolism; Liver; Male; Methionine; Obesity	2018
Metabolic Regulation of Methionine Restriction in Diabetes. Molecular nutrition & food research, 2018, Volume: 62, Issue:10 Topics: Animals; Autophagy; Diabetes Mellitus; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Methionine; Oxidative Stress; Pentose Phosphate Pathway	2018
Methionine restriction on lipid metabolism and its possible mechanisms. Amino acids, 2016, Volume: 48, Issue:7 Topics: Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lipid Metabolism; Methionine; Obesity	2016
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. Advances in nutrition (Bethesda, Md.), 2011, Volume: 2, Issue:6 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine	2011
Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents. Experimental gerontology, 2013, Volume: 48, Issue:7 Topics: Adaptation, Physiological; Adiposity; Age Factors; Aging; Animals; Diet; Energy Metabolism; Humans; Insulin Resistance; Methionine; Mice; Oxidative Stress; Phenotype; Rats; Rodentia	2013
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition. The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:3 Topics: Betaine; Cytokines; Dietary Supplements; Environmental Exposure; Fatty Liver; Female; Humans; Insulin Resistance; Life Style; Liver; Liver Cirrhosis; Metabolic Syndrome; Methionine; Middle Aged; Mitochondrial Diseases; Oxidative Stress; S-Adenosylmethionine; United States; Vitamin E; Xenobiotics; Zinc	2007

Trials

4 trial(s) available for methionine and Insulin Sensitivity

Article	Year
The effects of Zinc-Methionine on glucose metabolism and insulin resistance during late pregnancy in ewes. Domestic animal endocrinology, 2021, Volume: 77 Topics: Animals; Blood Glucose; Dietary Supplements; Fatty Acids, Nonesterified; Female; Glucose; Insulin; Insulin Resistance; Lactation; Methionine; Pregnancy; Sheep; Zinc	2021
Effects of fat-enriched diet and methionine on insulin sensitivity in lactating cows. Journal of animal science, 2015, Volume: 93, Issue:6 Topics: Animals; Cattle; Cholesterol; Diet, High-Fat; Dietary Fats; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids; Female; Glucose; Insulin; Insulin Resistance; Lactation; Lipid Metabolism; Methionine; Milk; Rumen	2015
Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:5 Topics: Adipose Tissue; Biomarkers; Body Composition; Cohort Studies; Cystine; Diet; Dietary Fats; Double-Blind Method; Energy Metabolism; Fats; Female; Glucose; Humans; Insulin Resistance; Kinetics; Liver; Male; Metabolic Syndrome; Methionine; Middle Aged; Obesity; Oxidation-Reduction; Waist Circumference	2011
Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: a population-based study. American journal of human genetics, 1996, Volume: 59, Issue:5 Topics: Blood Glucose; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Netherlands; Point Mutation; Receptor, Insulin; Risk	1996

Other Studies

50 other study(ies) available for methionine and Insulin Sensitivity

Article	Year
HPS protects the liver against steatosis, cell death, inflammation, and fibrosis in mice with steatohepatitis. The FEBS journal, 2022, Volume: 289, Issue:17 Topics: Animals; Apoptosis; Diet, High-Fat; Disease Models, Animal; Humans; Inflammation; Insulin Resistance; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease	2022
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan. Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:8 Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine	2022
Association between methyl donor nutrients and metabolic health status in overweight and obese adolescents. Scientific reports, 2022, 10-11, Volume: 12, Issue:1 Topics: Adolescent; Betaine; Body Mass Index; Choline; Cross-Sectional Studies; Female; Health Status; Humans; Insulin Resistance; Iran; Lipids; Metabolic Syndrome; Methionine; Nutrients; Overweight; Pediatric Obesity; Vitamins	2022
Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle. Nature communications, 2023, 02-16, Volume: 14, Issue:1 Topics: Aged; Aging, Premature; Animals; Humans; Insulin Resistance; Methionine; Methionine Adenosyltransferase; Mice; Muscle, Skeletal; Racemethionine; Signal Transduction	2023
Dietary Methionine Restriction Improves Gastrocnemius Muscle Glucose Metabolism through Improved Insulin Secretion and H19/IRS-1/Akt Pathway in Middle-Aged Mice. Journal of agricultural and food chemistry, 2023, Apr-12, Volume: 71, Issue:14 Topics: Animals; Glucose; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin Secretion; Methionine; Mice; Muscle, Skeletal; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Racemethionine	2023
Hyperhomocysteinemia activates NLRP3 inflammasome to cause hepatic steatosis and insulin resistance via MDM2-mediated ubiquitination of HSF1. International immunopharmacology, 2023, Volume: 118 Topics: Animals; Heat Shock Transcription Factors; Hyperhomocysteinemia; Inflammasomes; Insulin Resistance; Liver; Methionine; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Ubiquitination	2023
Placental extract ameliorates liver fibrosis in a methionine- and choline-deficient diet-induced mouse model of non-alcoholic steatohepatitis. Biomedical research (Tokyo, Japan), 2020, Volume: 41, Issue:1 Topics: Animal Feed; Animals; Body Weight; Choline; Diet; Disease Models, Animal; Female; Hepatic Stellate Cells; Humans; Inflammation; Insulin Resistance; Liver; Liver Cirrhosis; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Placenta; Placental Extracts; Pregnancy; Reactive Oxygen Species; Smad Proteins	2020
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice. Journal of agricultural and food chemistry, 2020, Apr-29, Volume: 68, Issue:17 Topics: Adipose Tissue, Brown; Animals; Anti-Obesity Agents; Diet, High-Fat; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lysine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Threonine; Uncoupling Protein 1	2020
The PNPLA3-I148M Variant Confers an Antiatherogenic Lipid Profile in Insulin-resistant Patients. The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1 Topics: Adult; Amino Acid Substitution; Atherosclerosis; Cohort Studies; Cross-Sectional Studies; Disease Resistance; Female; Finland; Genetic Association Studies; Humans; Insulin Resistance; Isoleucine; Lipase; Lipid Metabolism; Lipidomics; Lipoproteins; Male; Membrane Proteins; Methionine; Middle Aged; Polymorphism, Single Nucleotide	2021
Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. Clinical science (London, England : 1979), 2017, 06-01, Volume: 131, Issue:12 Topics: Amino Acid Oxidoreductases; Animals; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Choline Deficiency; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Induction; Extracellular Matrix; Forkhead Box Protein O1; Genetic Predisposition to Disease; Hepatic Stellate Cells; Hepatocytes; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Methionine; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phenotype; Receptor, Insulin; Signal Transduction	2017
Maternal methyl donor and cofactor supplementation in late pregnancy increases β-cell numbers at 16 days of life in growth-restricted twin lambs. American journal of physiology. Endocrinology and metabolism, 2017, 10-01, Volume: 313, Issue:4 Topics: Animals; Animals, Newborn; Blood Glucose; Body Composition; Case-Control Studies; Cell Count; Cobalt; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Methionine; Pancreas; Pregnancy; Pregnancy, Twin; Prenatal Exposure Delayed Effects; Sheep; Sulfur	2017
Dietary Methionine Restriction Alleviates Hyperglycemia in Pigs with Intrauterine Growth Restriction by Enhancing Hepatic Protein Kinase B Signaling and Glycogen Synthesis. The Journal of nutrition, 2017, Volume: 147, Issue:10 Topics: Animal Feed; Animals; Animals, Newborn; Birth Weight; Blood Glucose; Diabetes Mellitus, Type 2; Diet; Female; Fetal Growth Retardation; Glucose-6-Phosphatase; Glycogen; Hyperglycemia; Insulin Resistance; Liver; Male; Methionine; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Swine; Weaning	2017
The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2018, Volume: 43, Issue:2 Topics: Adiponectin; Animals; Cold Temperature; Diet; Down-Regulation; Energy Intake; Energy Metabolism; Fibroblast Growth Factors; Insulin; Insulin Resistance; Leptin; Liver; Male; Methionine; Mice; Mice, Knockout; Stearoyl-CoA Desaturase; Thermogenesis; Triglycerides; Uncoupling Protein 1	2018
Lower plasma trans-4-hydroxyproline and methionine sulfoxide levels are associated with insulin dysregulation in horses. BMC veterinary research, 2018, May-02, Volume: 14, Issue:1 Topics: Animals; Blood Glucose; Glucose Tolerance Test; Horses; Hydroxyproline; Insulin; Insulin Resistance; Metabolomics; Methionine	2018
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF- The Journal of biological chemistry, 2018, 08-24, Volume: 293, Issue:34 Topics: Animals; Benzofurans; Brain-Derived Neurotrophic Factor; CD36 Antigens; Cell Differentiation; Diet, High-Fat; Insulin Resistance; Intra-Abdominal Fat; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mutation; Obesity; Valine	2018
Gamma-Tocotrienol Attenuates the Hepatic Inflammation and Fibrosis by Suppressing Endoplasmic Reticulum Stress in Mice. Molecular nutrition & food research, 2018, Volume: 62, Issue:21 Topics: Animals; Body Weight; Cholesterol; Chromans; Diet, Western; Dietary Supplements; Endoplasmic Reticulum Stress; Fibrosis; Hepatitis; Insulin Resistance; Liver; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Triglycerides; Vitamin E	2018
Effects of dietary methionine restriction on postnatal growth, insulin sensitivity, and glucose metabolism in intrauterine growth retardation pigs at 49 and 105 d of age. Journal of animal science, 2019, Feb-01, Volume: 97, Issue:2 Topics: Animals; Blood Glucose; Female; Fetal Growth Retardation; Glucose; Insulin Resistance; Litter Size; Liver; Male; Methionine; Muscles; Phosphorylation; Proto-Oncogene Proteins c-akt; Swine; Swine Diseases; Weaning	2019
Remodeling the integration of lipid metabolism between liver and adipose tissue by dietary methionine restriction in rats. Diabetes, 2013, Volume: 62, Issue:10 Topics: Adipose Tissue, White; Animals; Biomarkers; Blotting, Western; Diet; Down-Regulation; Eating; Energy Metabolism; Fatty Acids; Gene Expression; Insulin Resistance; Leucine; Lipid Metabolism; Liver; Male; Methionine; Mitochondria; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction	2013
Dietary glycotoxins exacerbate progression of experimental fatty liver disease. Journal of hepatology, 2014, Volume: 60, Issue:4 Topics: Animals; Cell Proliferation; Choline Deficiency; Diet; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hepatic Stellate Cells; Insulin Resistance; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Rats, Sprague-Dawley	2014
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. Aging cell, 2014, Volume: 13, Issue:5 Topics: Animals; Energy Metabolism; Fibroblast Growth Factors; Gene Expression; Glucose; Insulin Resistance; Lipid Metabolism; Male; Methionine; Mice; Mice, Inbred C57BL; Obesity; Phenotype	2014
Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. Diabetes, 2014, Volume: 63, Issue:11 Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Deoxyglucose; Fibroblast Growth Factors; Hep G2 Cells; Humans; Insulin Resistance; Liver; Methionine; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt	2014
Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice. Metabolism: clinical and experimental, 2015, Volume: 64, Issue:2 Topics: Allostasis; Animals; Crosses, Genetic; Energy Intake; Female; Glucose Intolerance; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Methionine; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Random Allocation; Receptor, Insulin; Signal Transduction; Weight Loss	2015
Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle. PloS one, 2015, Volume: 10, Issue:1 Topics: Animals; Burns; Farnesyltranstransferase; Insulin Resistance; Male; Methionine; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Protein Prenylation	2015
UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:6 Topics: Adipose Tissue, White; Adiposity; Animals; Blood Glucose; Blotting, Western; Diet; Energy Metabolism; Fatty Acids; Gene Expression; Genotype; Insulin; Insulin Resistance; Ion Channels; Male; Metabolomics; Methionine; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Uncoupling Protein 1	2015
Noninvasive estimation of disease activity and liver fibrosis in nonalcoholic fatty liver disease using anthropometric and biochemical characteristics, including insulin, insulin resistance, and 13C-methionine breath test. European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:10 Topics: Anthropometry; Biomarkers; Breath Tests; Carbon Isotopes; Female; gamma-Glutamyltransferase; Humans; Insulin; Insulin Resistance; Liver Cirrhosis; Male; Methionine; Middle Aged; Non-alcoholic Fatty Liver Disease; ROC Curve	2015
Altered distribution of regulatory lymphocytes by oral administration of soy-extracts exerts a hepatoprotective effect alleviating immune mediated liver injury, non-alcoholic steatohepatitis and insulin resistance. World journal of gastroenterology, 2015, Jun-28, Volume: 21, Issue:24 Topics: Administration, Oral; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Choline Deficiency; Concanavalin A; Cytoprotection; Diet, High-Fat; Disease Models, Animal; Glycine max; Immunologic Factors; Insulin; Insulin Resistance; Lipids; Liver; Metabolic Syndrome; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Plant Extracts; T-Lymphocytes, Regulatory; Time Factors; Tumor Necrosis Factor-alpha	2015
Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice. Obesity (Silver Spring, Md.), 2015, Volume: 23, Issue:9 Topics: Adipose Tissue; Adiposity; Animals; Insulin Resistance; Liver; Male; Methionine; Mice; Obesity	2015
Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice. Redox biology, 2016, Volume: 10 Topics: Aging; Animals; Cytosol; Female; Insulin Resistance; Longevity; Male; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Transgenic; Mitochondria; Models, Animal; Oxidative Stress	2016
FGF21 Mediates the Thermogenic and Insulin-Sensitizing Effects of Dietary Methionine Restriction but Not Its Effects on Hepatic Lipid Metabolism. Diabetes, 2017, Volume: 66, Issue:4 Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blotting, Western; Diet, High-Fat; Energy Metabolism; Fibroblast Growth Factors; Gene Expression; Glucose Clamp Technique; Insulin Resistance; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Knockout; Obesity; Real-Time Polymerase Chain Reaction; Thermogenesis; Triglycerides	2017
Metabolism of methionine in vivo: impact of pregnancy, protein restriction, and fatty liver disease. Nestle Nutrition workshop series. Paediatric programme, 2009, Volume: 63 Topics: Animals; Diet, Protein-Restricted; Disease Models, Animal; Fatty Liver; Female; Fetal Growth Retardation; Folic Acid; Humans; Insulin Resistance; Methionine; Models, Animal; Pregnancy	2009
The role of chronic inflammation and Leu55Met PON1 polymorphism in the pathogenesis of polycystic ovary syndrome. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2010, Volume: 26, Issue:9 Topics: Adult; Amino Acid Substitution; Aryldialkylphosphatase; Case-Control Studies; Chronic Disease; Female; Glucose Tolerance Test; Humans; Inflammation; Insulin Resistance; Leucine; Methionine; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Testosterone; Young Adult	2010
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention. Physiological genomics, 2011, Apr-27, Volume: 43, Issue:8 Topics: Animals; Blood Glucose; Carbon; Cholesterol; Choline; Dietary Fats; Fatty Liver; Hyperglycemia; Insulin; Insulin Resistance; Liver; Methionine; Mice; Mice, Inbred C57BL; Obesity; Triglycerides	2011
Inhibition of hepatic glycogen synthesis by hyperhomocysteinemia mediated by TRB3. The American journal of pathology, 2011, Volume: 178, Issue:4 Topics: Animals; Cell Cycle Proteins; Disease Progression; Glycogen; Homocysteine; Humans; Hyperhomocysteinemia; Indoles; Insulin Resistance; Liver Glycogen; Methionine; Mice; Phosphorylation; PPAR gamma; Protein Serine-Threonine Kinases; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering	2011
Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine. Clinical science (London, England : 1979), 2011, Volume: 121, Issue:4 Topics: Adipokines; Adult; Aged; Calorimetry, Indirect; Case-Control Studies; Cysteine; Fatty Liver; Female; Glutathione; Homocysteine; Humans; Inflammation Mediators; Insulin Resistance; Liver; Male; Methionine; Methylation; Middle Aged; Non-alcoholic Fatty Liver Disease; Phenylalanine; Proteins; Urea; Young Adult	2011
Dietary methyl-consuming compounds and metabolic syndrome. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:12 Topics: Animals; Arsenicals; Catecholamines; Diet; Folic Acid; Homocysteine; Humans; Hypolipidemic Agents; Insulin Resistance; Metabolic Syndrome; Methionine; Niacin; Reactive Oxygen Species	2011
Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4 Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline Deficiency; Cytokines; Diet; Fatty Liver; Gene Expression; Glutathione; Insulin Resistance; Isoprostanes; JNK Mitogen-Activated Protein Kinases; Liver; Male; Methionine; Mice; Myocardium; Nitrates; Nitrites; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Silybin; Silymarin; Statistics, Nonparametric	2012
Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. Clinical science (London, England : 1979), 2012, Volume: 123, Issue:12 Topics: Analysis of Variance; Animals; Arachidonic Acid; Benzofurans; Choline; Clodronic Acid; Diet, High-Fat; DNA Primers; Fatty Acids, Unsaturated; Fatty Liver; Gadolinium; Hemodynamics; Hypertension, Portal; Insulin Resistance; Kupffer Cells; Leptin; Methionine; Methoxamine; Microcirculation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfonylurea Compounds; Thiobarbituric Acid Reactive Substances; Thromboxane A2	2012
Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density. PloS one, 2012, Volume: 7, Issue:12 Topics: Adiponectin; Analysis of Variance; Animals; Bone Density; Collagen Type I; Diet, High-Fat; Disease Resistance; DNA Primers; Fibroblast Growth Factors; Gene Expression Profiling; Gene Expression Regulation; Glucose Tolerance Test; Histological Techniques; Insulin Resistance; Insulin-Like Growth Factor I; Leptin; Methionine; Mice; Mice, Inbred C57BL; Obesity; Real-Time Polymerase Chain Reaction; Rotarod Performance Test	2012
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. Journal of hepatology, 2004, Volume: 40, Issue:1 Topics: Alanine Transaminase; Animals; Blood Glucose; Choline Deficiency; Deficiency Diseases; Fasting; Fatty Liver; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Methionine; Mice; Mice, Inbred Strains	2004
Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes, 2005, Volume: 54, Issue:11 Topics: Animals; Betaine; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hepatocytes; Homocysteine; Insulin Resistance; Liver; Methionine; Phosphatidylcholines; Rats; Rats, Zucker; RNA, Messenger	2005
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterology, 2007, Volume: 132, Issue:1 Topics: Animal Feed; Animals; Choline; Collagen Type I; Collagen Type I, alpha 1 Chain; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Methionine; Obesity; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; Rats; Rats, Inbred OLETF; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Thiazolidinediones; Transforming Growth Factor beta; Up-Regulation	2007
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-04, Volume: 104, Issue:49 Topics: Animals; Animals, Newborn; Blood Pressure; Body Composition; Diet; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Fertilization; Folic Acid; Glucose; Heart Rate; Immunity; Insulin Resistance; Methionine; Pregnancy; Pregnancy Outcome; Sheep; Vitamin B 12; Vitamin B Complex	2007
Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects. European journal of pharmacology, 2008, Jul-07, Volume: 588, Issue:2-3 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Choline Deficiency; Disease Models, Animal; Fatty Acids; Fatty Liver; Imidazoles; Insulin Resistance; Liver Cirrhosis, Experimental; Male; Methionine; Oxidative Stress; Rats; Rats, Long-Evans; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2008
Homozygosity for a new mutation (Ile119-->Met) in the insulin receptor gene in five sibs with familial insulin resistance. Journal of medical genetics, 1994, Volume: 31, Issue:9 Topics: Exons; Female; Homozygote; Humans; Insulin Resistance; Isoleucine; Lod Score; Male; Methionine; Mutation; Pedigree; Receptor, Insulin	1994
A mutation in the insulin receptor that impairs proreceptor processing but not insulin binding. The Journal of biological chemistry, 1994, May-13, Volume: 269, Issue:19 Topics: Animals; Base Sequence; Blotting, Western; Cells, Cultured; CHO Cells; Cricetinae; Female; Fibroblasts; Glycosylation; Humans; Infant, Newborn; Insulin; Insulin Resistance; Methionine; Molecular Sequence Data; Mutation; Protein Precursors; Protein Processing, Post-Translational; Receptor, Insulin	1994
The sulfonylurea drug, glimepiride, stimulates glucose transport, glucose transporter translocation, and dephosphorylation in insulin-resistant rat adipocytes in vitro. Diabetes, 1993, Volume: 42, Issue:12 Topics: Adipocytes; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Epididymis; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Male; Methionine; Monosaccharide Transport Proteins; Muscle Proteins; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Wistar; Sulfonylurea Compounds; Sulfur Radioisotopes	1993
The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance. American journal of human genetics, 1997, Volume: 60, Issue:6 Topics: Blood Glucose; C-Peptide; Denmark; Diabetes Mellitus, Type 2; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Methionine; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Insulin; Reference Values; Valine; White People	1997
A mutation in the tyrosine kinase domain of the insulin receptor associated with insulin resistance in an obese woman. The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:4 Topics: Adult; Exons; Female; Fibroblasts; Humans; Insulin Resistance; Isoleucine; Methionine; Mutation; Obesity; Protein-Tyrosine Kinases; Receptor, Insulin	1991
Insulin-receptor biosynthesis in cultured lymphocytes from an insulin-resistant patient (Rabson-Mendenhall syndrome). Evidence for defect before insertion of receptor into plasma membrane. Diabetes, 1986, Volume: 35, Issue:7 Topics: Cell Membrane; Cells, Cultured; Humans; Insulin Resistance; Lymphocytes; Mannose; Methionine; Protein Precursors; Radioligand Assay; Receptor, Insulin; Syndrome	1986
Insulin receptor biosynthesis in cultured lymphocytes from insulin-resistant patients. The Journal of clinical investigation, 1985, Volume: 76, Issue:6 Topics: Cells, Cultured; Diabetes Mellitus; Glycoproteins; Humans; Insulin Resistance; Lymphocytes; Mannose; Methionine; Protein Precursors; Protein Processing, Post-Translational; Receptor, Insulin	1985