Compounds > methionine
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methionine and Hepatocellular Carcinoma

methionine has been researched along with Hepatocellular Carcinoma in 138 studies

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-199075 (54.35)18.7374
1990's22 (15.94)18.2507
2000's14 (10.14)29.6817
2010's17 (12.32)24.3611
2020's10 (7.25)2.80

Authors

AuthorsStudies
Chen, D; Piao, H; Wang, W1
Agopian, V; Ayoub, W; Benhammou, JN; Choi, G; Dong, TS; Durazo, F; Elashoff, D; Enayati, P; Fiehn, O; Goodman, MT; Hussain, SK; Jacobs, JP; Lagishetty, V; Noureddin, M; Pisegna, JR; Sundaram, V1
Chen, PM; Chiang, EI; Huang, CC; Hwang, HH; Ko, HA; Li, JR; Liu, CC; Tsai, CH1
Fang, AP; He, TT; Liu, XZ; Liu, ZY; Luo, Y; Wusiman, M; Xiao, HW; Yishake, D; Zhu, HL1
Guo, H; Hu, R; Huang, L; Kong, X; Qian, Y; Sha, M; Xia, Q; Xu, D; Zhang, X; Zhang, Y1
Abe, A; Miyajima, K; Nakae, D; Nakane, S; Suzuki-Kemuriyama, N; Yuki, M1
Antwi, SO; Campbell, PT; Liao, LM; McGlynn, KA; Norez, DA; Patel, T; Petrick, JL; Roberts, LR; Stevens, VL1
Guo, Z; Jin, C; Li, Y; Shao, J; Su, Y; Wang, S; Wang, X; Zhang, F; Zhang, Z; Zheng, S1
Buechler, C; Haberl, EM; Höring, M; Krautbauer, S; Liebisch, G; Pohl, R; Rein-Fischboeck, L1
Budhu, A; Chaisaingmongkol, J; Chang, CW; Diggs, LP; Forgues, M; Greten, TF; Heinrich, S; Hung, MH; Lee, JS; Ma, C; Ma, L; Ruchirawat, M; Ruppin, E; Wang, XW1
Channa, IS; Hashim, Z; Ilyas, A; Zarina, S1
Columbano, A; Orrù, C; Perra, A; Szydlowska, M; Taguchi, K; Yamamoto, M; Zavattari, P1
Corn, DJ; Kuang, Y; Lee, Z; Tian, H; Wang, F2
Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM1
Hatano, E; Koyama, Y; Nakamura, K; Seo, S; Takemoto, K; Tanabe, K; Taura, K; Toriguchi, K; Uemoto, S1
Barghash, A; Bohle, RM; Cadenas, C; Gemperlein, K; Gianmoena, K; Haybaeck, J; Helms, V; Hengstler, JG; Kessler, SM; Kiemer, AK; Lammert, F; Mueller, R; Pokorny, J; Simon, Y; van Rooijen, N; Zimmer, V1
Banwat, E; Chetwood, J; Crossey, MM; Dona, AC; Duguru, M; Fye, HK; Garside, DA; Holmes, E; Kasstan, B; Khan, SA; Ladep, NG; Lemoine, M; Lewis, MR; Nicholson, JK; Njai, HF; Njie, R; Okeke, E; Shimakawa, Y; Taal, M; Taylor-Robinson, SD; Thillainayagam, AV; Thursz, MR; Wijeyesekera, A1
Egger, M; Eggert, T; ElGindi, M; Felsher, DW; Greten, TF; Han, M; Heikenwalder, M; Jin, P; Kapoor, V; Kesarwala, AH; Kleiner, DE; Luo, J; Ma, C; McVicar, DW; Medina-Echeverz, J; Stroncek, DF; Terabe, M; Thornton, AM; Weber, A; Zhang, H1
Chung, I; Ha, CS; Hyun, J; Jung, Y; Kim, J; Kim, SW; Park, SY; Rao, KM; Wang, S; Yun, YH1
Bagnyukova, TV; Beland, FA; Muskhelishvili, L; Pogribny, IP; Ross, SA; Tryndyak, VP1
Elias, MS; Green, RM; Henkel, AS1
Choi, SH; Kim, HY; Kim, JR; Kwak, GH1
Funabiki, R; Kawasaki, M; Miura, Y; Yagasaki, K2
Bosserhoff, AK; Dettmer, K; Hellerbrand, C; Kirovski, G; Oefner, PJ; Samejima, K; Stevens, AP1
Lu, SC; Mato, JM1
Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC1
Kaneoka, Y; Kumada, T; Maeda, A; Toyoda, H1
Alberto, JM; Ayav, A; Bressenot, A; Bronowicki, JP; Chéry, C; Fofou-Caillierez, M; Forges, T; Guéant, JL; Namour, F; Pellanda, H1
Avila, MA; García-Trevijano, ER; Latasa, MU; Lu, SC; Martínez-Chantar, ML; Mato, JM; Varela-Rey, M1
Choudhury, P; Datta, B; Datta, R; Ghosh, A1
GIUDICE, G; MAGGIO, R; MUTOLO, V1
CHO, YS; MORRIS, HP; PITOT, HC1
KINOSITA, R; MIYAJI, H1
BURNS, JJ; CONNEY, AH1
DUNN, WL1
MANGIANTINI, M1
Avila, MA; Caballería, J; Corrales, FJ; Fernández-Irigoyen, J; Lu, SC; Mato, JM; Muñoz, J; Prieto, J; Riezu, JI; Santamaría, E; Sesma, L1
Bierczyńska-Krzysik, A; Bonar, E; Dubin, A; Koj, A; Noga, M; Silberring, J; Stalińska, K1
Banerjee, R; Bauman, Z; Braun, A; Lu, SC; Prudova, A; Vitvitsky, V1
Bai, S; Datta, J; Frankel, W; Ghoshal, K; Jacob, ST; Kutay, H; Motiwala, T; Pogribny, I1
Calvisi, DF; De Miglio, MR; De Murtas, V; Feo, F; Frau, M; Ladu, S; Muroni, MR; Pascale, RM; Pellegrino, R; Pinna, F; Simile, MM; Tomasi, ML; Virdis, P1
Kanegae, K; Kohanawa, M; Kuge, Y; Seki, K; Takahashi, T; Tamaki, N; Yi, M; Zhao, S; Zhao, Y1
Aransay, AM; Ariz, U; Calvisi, DF; Capdevila, A; Esteller, M; Fraga, M; Lu, SC; Luka, Z; Martínez, N; Martínez-Chantar, ML; Mato, JM; Matthiesen, R; Rodríguez, J; Varela, M; Vázquez-Chantada, M; Wagner, C; Yang, H1
Bartalena, L; Robbins, J; Tata, JR1
Hirose, S; Nagasue, N; Ogawa, Y; Sasaki, Y; Yukaya, H1
Baumann, H; Doyle, D; Gelehrter, TD1
Higashi, T1
Obrist, R; Sandberg, AL1
Colman, RW; Glasgow, JE1
Potvin, B; Stanley, P; Stockert, RJ; Tao, L; Wolkoff, AW1
Akiyama, S; Gottesman, MM; Pastan, I; Schoenlein, P; Shen, DW1
Matsumata, T; Nishizaki, T; Sugimachi, K; Taketomi, A; Yamamoto, K1
Liu, J; Liu, JH; Marumo, F; Miyakawa, H; Mori, K; Sato, C; Takano, T1
Bereziat, G; Janvier, B; Loriette, C; Mangeney-Andreani, M; Vandenbrouck, Y1
Lo, SJ; Sheu, SY1
Guo, P; Maloney, B; Nodgreen, R; Scholz, E; Turek, J1
Bonifácio, MJ; Breakfield, XO; Ezzeddine, D; Sakaki, Y; Saraiva, MJ1
Beck, SC; Buchman, TG; De Maio, A1
Kong, N; Lodish, HF1
Cederbaum, AI; Yang, MX1
Henning, SM; Ivandic, BT; Liao, F; Swendseid, ME1
Biller, SA; Chen, Y; Chu, CH; Dickson, JK; Gordon, DA; Gregg, RE; Jamil, H; Wetterau, JR; Yan, M1
Funabiki, R; Kawasaki, M; Yagasaki, K1
Kokuba, Y; Matsuda, A; Sasamura, T1
Chen, WN; Leong, AL; Oon, CJ; Teng, SW; Zhao, Y1
Avila, MA; Berasain, C; Caballería, J; Corrales, FJ; Lu, SC; Martín-Duce, A; Mato, JM; Prieto, J; Rodés, J; Torres, L; Yang, H1
Chen, YH; Cheng, JT; Chern, CL; Huang, RF; Liu, TZ1
Poirier, LA2
Rogers, AE1
Ezirike, J; Kim, S; Morris, HP; Paik, WK1
Ishikawa, R; Kusakabe, K; Maki, M; Ono, Y; Yamasaki, T1
Hilliard, JK; Sneider, TW1
Hurlbert, RB; Liau, MC; Lin, GW1
Alexander, JJ; Deinhardt, F; Frösner, GG; Hofschneider, PH; Zaslavsky, V1
Freikopf, A; Kulka, RG1
Borén, J; Graham, L; Olofsson, SO; Scott, J; Wettesten, M; White, A1
Geuze, HJ; Rijnboutt, S; Stoorvogel, W; Strous, GJ1
Burkey, BF; Degen, SJ; Jamison, CS1
Baumann, H; Won, KA1
Hiramoto, M; Imaizumi, T; Kawamura, Y; Satoh, K; Takamatsu, M; Takamatsu, S; Yoshida, H1
Donadel, G; Frank, R; Gabrielli, F; Garzelli, C1
Olden, K; Yeo, KT; Yeo, TK1
Beale, EG; Granner, DK; Leverence, RR1
Cooper, AD; Craig, WY; Nutik, R1
Hashimoto, S; Morito, F; Saito, H; Suzuki, K1
Blau, R; Burk, M; Stoffel, W1
Bondjers, G; Borén, J; Boström, K; Carrella, M; Jarfeldt, M; Norfeldt, PI; Olofsson, SO; Wettesten, M; Wiklund, O1
Armellino, D; Jaffe, EA; Tollefsen, DM1
Olson, JW1
Antonelli, A; Bartalena, L; Martino, E; Pacchiarotti, A; Pinchera, A; Robbins, J1
Barsigian, C; Base, W; Fish, S; Gilman, P; Martinez, J; Schaeffer, A1
Silverman, D; vanderSpek, J; Zannis, VI1
Cooper, AD; Ellsworth, JL; Erickson, SK1
Newberne, PM1
Gottschalk, A; Hoffer, PB1
Pitot, HC; Weiss, JW2
Morris, HP; Petri, WA; Poirier, LA1
Hancock, RL2
Donnell, GN; Koch, R; Lieberman, E; Shaw, KN1
Busch, H; Nakamura, T; Prestayko, AW1
Bilik, E; Sheid, B2
Potter, VR; Sneider, TW1
Ben-Porath, M; Kaplan, E1
Busch, H; Hodnett, JL; Moriyama, Y; Prestayko, AW1
Craddock, VM1
Kerr, SJ1
Wolberg, WH1
Flatt, NC; Hurlbert, RB; Liau, MC1
Eddleston, AL; Osborn, SB; Pagaltsos, AP; Rake, MO; Williams, R1
Sneider, TW1
Byvoet, P2
Anderson, JE; Perlmutter, GS1
Hurlbert, RB; Liau, MC; O'Rourke, CM1
Inose, M; Iwanami, Y; Miyata, S1
Sneider, T1
Agostini, C; Comi, P; Mortara, G1
Stolzenberg, J1
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ1
Burdine, JA; Calderon, M; Goyal, RK; Grubb, MN; Hersh, T; Kaldenbaugh, H1
Bancons, J; Blanquet, P; Dubarry, JJ; Ducassou, D; Leccia, MF; Quinton, A1
Pitot, HC; Wilkinson, DS1
Kusakabe, K1
Murty, CN; Sidransky, H; Verney, E1
Nau, F1
Finkelstein, JD; Grossman, MR; Kyle, WE; Morris, HP1
Baliga, BS; Borek, E; Nielsen, HR; Nyholm, K; Sjolin, KE; Wong, R1
Bouali, AB; Cheguillaume, J; Joubaud, F; Minier, J; Pithon, G1
Howard, E; Tidwell, T1
Kartenbeck, J; Schreiber, G; Schreiber, M1
Johnson, PM; Muroff, LR1
Inose, M; Iwanami, Y1

Reviews

2 review(s) available for methionine and Hepatocellular Carcinoma

ArticleYear
The hepatocarcinogenic effect of methionine and choline deficient diets: an adaptation to the Warburg effect?
    Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:5

    Topics: Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Humans; Liver Neoplasms; Methionine

2011
Tumor scanning agents.
    Seminars in nuclear medicine, 1974, Volume: 4, Issue:3

    Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms

1974

Other Studies

136 other study(ies) available for methionine and Hepatocellular Carcinoma

ArticleYear
[Identification of
    Se pu = Chinese journal of chromatography, 2021, Volume: 39, Issue:10

    Topics: Animals; Carcinoma, Hepatocellular; Chromatography, Liquid; Disease Models, Animal; Inflammation; Liver; Liver Neoplasms; Mass Spectrometry; Methionine; Mice

2021
Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:8

    Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Microbiota; Proportional Hazards Models; Prospective Studies; Risk Factors; Taurocholic Acid

2022
Downregulation of Methionine Cycle Genes
    International journal of molecular sciences, 2022, Jan-01, Volume: 23, Issue:1

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Down-Regulation; Eukaryotic Initiation Factor-3; Gene Expression Regulation, Neoplastic; Glycine N-Methyltransferase; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasm Invasiveness; Peptide Elongation Factor 1; Promoter Regions, Genetic; Protein Biosynthesis; Survival Analysis

2022
Dietary intake of one-carbon metabolism-related nutrients and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort.
    Food & function, 2022, Aug-01, Volume: 13, Issue:15

    Topics: Carbon; Carcinoma, Hepatocellular; Cohort Studies; Diet; Eating; Folic Acid; Humans; Liver Neoplasms; Methionine; Nutrients; Prospective Studies; Risk Factors

2022
A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response.
    Stem cell research & therapy, 2022, 07-15, Volume: 13, Issue:1

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Self Renewal; Chemoembolization, Therapeutic; Cholangiocarcinoma; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase

2022
Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fibrosis; Interleukin-8; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2023
One-carbon metabolism-related micronutrients intake and risk for hepatocellular carcinoma: A prospective cohort study.
    International journal of cancer, 2020, 10-15, Volume: 147, Issue:8

    Topics: Carbon; Carcinoma, Hepatocellular; Diet; Dietary Supplements; Eating; Female; Folic Acid; Humans; Liver Neoplasms; Male; Methionine; Micronutrients; Middle Aged; Nutritional Status; Prospective Studies; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2020
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
    Cell death & disease, 2020, 10-11, Volume: 11, Issue:10

    Topics: Amino Acid Transport Systems; Animals; Calcium-Binding Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cellular Senescence; Coordination Complexes; Copper; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Telomerase; Transfection; Xenograft Model Antitumor Assays

2020
Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease.
    Lipids in health and disease, 2020, Dec-09, Volume: 19, Issue:1

    Topics: alpha-Fetoproteins; Animal Feed; Animals; Carcinoma, Hepatocellular; Ceramides; Choline; Choline Deficiency; Diethylnitrosamine; Disease Models, Animal; Humans; Lipidomics; Lipids; Lipogenesis; Liver; Liver Cirrhosis; Liver Neoplasms; Lysophosphatidylcholines; Male; Mass Spectrometry; Methionine; Mice; Mice, Inbred C3H; Non-alcoholic Fatty Liver Disease; Oxidative Stress

2020
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
    Nature communications, 2021, 03-05, Volume: 12, Issue:1

    Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Line, Tumor; CRISPR-Cas Systems; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylmethionine; T-Lymphocytes; Transcriptome

2021
Alendronate and FTI-277 combination as a possible therapeutic approach for hepatocellular carcinoma: An in vitro study.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2018, Volume: 17, Issue:3

    Topics: Alendronate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methionine; Proteomics; Signal Transduction; Tandem Mass Spectrometry; Time Factors

2018
Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis.
    Journal of hepatology, 2018, Volume: 69, Issue:3

    Topics: Alkylating Agents; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Gene Silencing; Lipotropic Agents; Liver Neoplasms; Methionine; NF-E2-Related Factor 2; Rats; Treatment Outcome

2018
Metabolism of radiolabeled methionine in hepatocellular carcinoma.
    Molecular imaging and biology, 2014, Volume: 16, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cycloheximide; Hepatocytes; Liver Neoplasms; Marmota; Methionine; Protein Biosynthesis; Radionuclide Imaging; Radiopharmaceuticals; Rats; Solubility; Tritium; Water

2014
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; Drug Therapy, Combination; End Stage Liver Disease; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Neoplasms; Liver Transplantation; Male; Methionine; Middle Aged; Mutation; Retrospective Studies; Risk Factors; Secondary Prevention; Sex Factors; Tyrosine

2014
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5

    Topics: Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Choline Deficiency; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice, Inbred C57BL; Middle Aged; Molecular Targeted Therapy

2014
In vitro characterization of uptake mechanism of L-[methyl-(3)H]-methionine in hepatocellular carcinoma.
    Molecular imaging and biology, 2014, Volume: 16, Issue:4

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Cell Survival; Liver Neoplasms; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; Radionuclide Imaging; S-Adenosylmethionine; Transfection

2014
Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
    International journal of molecular sciences, 2014, Apr-04, Volume: 15, Issue:4

    Topics: Acetyltransferases; Animals; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Fatty Acid Elongases; Fatty Acids; Humans; Inflammation; Liver Neoplasms; Methionine; Mice; Mice, Inbred DBA; Mice, Obese; Non-alcoholic Fatty Liver Disease; RNA, Messenger

2014
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:4

    Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Choline; Creatine; Female; Humans; Ketoglutaric Acids; Liver Neoplasms; Male; Methionine; Middle Aged; Niacinamide; Phenotype; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Young Adult

2014
NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
    Nature, 2016, Mar-10, Volume: 531, Issue:7593

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Case-Control Studies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Choline; Diet; Disease Models, Animal; Genes, myc; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Liver; Liver Neoplasms; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species

2016
MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.
    Nature communications, 2016, Mar-22, Volume: 7

    Topics: Animals; Base Sequence; Carbon Tetrachloride; Carcinoma, Hepatocellular; Choline; Chronic Disease; Down-Regulation; Ethionine; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Kruppel-Like Transcription Factors; Liver Cirrhosis; Male; Methionine; Mice, Inbred C57BL; MicroRNAs; Molecular Sequence Data; Nanoparticles; Nerve Tissue Proteins; Protein Binding; Receptors, G-Protein-Coupled; RNA, Messenger; Smoothened Receptor; Transcription Factor RelA; Zinc Finger Protein Gli2; Zinc Finger Protein Gli3

2016
Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.
    Cell cycle (Georgetown, Tex.), 2008, Volume: 7, Issue:20

    Topics: Animals; Carcinoma, Hepatocellular; Diet; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Methionine; Methylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Random Allocation; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Transforming Growth Factor beta

2008
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
    The Journal of biological chemistry, 2009, Nov-13, Volume: 284, Issue:46

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response

2009
Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide.
    BMB reports, 2009, Sep-30, Volume: 42, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Free Radical Scavengers; Humans; Liver Neoplasms; Methionine; Methionine Sulfoxide Reductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Saccharomyces cerevisiae

2009
Comparison of the effects on lipid metabolism of dietary methionine and cystine between hepatoma-bearing and normal rats.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:1

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Cystine; Diet; Eating; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipolysis; Liver Neoplasms; Male; Methionine; Rats

2010
Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies.
    Journal of chromatography. A, 2010, May-07, Volume: 1217, Issue:19

    Topics: Calibration; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, Liquid; Humans; Liver Neoplasms; Methanol; Methionine; Polyamines; Purine-Nucleoside Phosphorylase; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tumor Cells, Cultured

2010
Effects of simultaneous dietary fish oil ingestion and sulfur amino acid supplementation on the lipid metabolism in hepatoma-bearing rats with hyperlipidemia.
    Journal of nutritional science and vitaminology, 2010, Volume: 56, Issue:4

    Topics: Adipose Tissue; Animals; Bile Acids and Salts; Carcinoma, Hepatocellular; Cholesterol; Cystine; Dietary Supplements; Fatty Acids; Feces; Fish Oils; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipoprotein Lipase; Liver; Male; Methionine; Rats; Rats, Inbred Strains; Sulfur

2010
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    The Journal of nutrition, 2011, Volume: 141, Issue:5

    Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine

2011
Amino acid substitutions in the hepatitis C virus core region are associated with postoperative recurrence and survival of patients with HCV genotype 1b-associated hepatocellular carcinoma.
    Annals of surgery, 2011, Volume: 254, Issue:2

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatectomy; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Leucine; Liver; Liver Function Tests; Liver Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Prognosis; RNA, Messenger; Survival Analysis; Viral Core Proteins

2011
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:2

    Topics: Alternative Splicing; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Creatinine; Humans; Imidazolidines; Liver Neoplasms; Methionine

2012
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine.
    The Journal of biological chemistry, 2003, May-30, Volume: 278, Issue:22

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; RNA, Messenger; S-Adenosylmethionine; Tumor Cells, Cultured

2003
A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.
    Biochemistry, 2003, May-13, Volume: 42, Issue:18

    Topics: Acetylglucosaminidase; Amino Acid Substitution; Aminopeptidases; Animals; Blotting, Western; Carcinoma, Hepatocellular; DNA Primers; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Glutathione Transferase; Glycoproteins; Glycosylation; Green Fluorescent Proteins; Liver Neoplasms; Luminescent Proteins; Methionine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Precipitin Tests; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Threonine; Tumor Cells, Cultured

2003
[The activation of methionine for transmethylation in regenerating rat liver and hepatoma].
    Zeitschrift fur Krebsforschung, 1958, Volume: 62, Issue:4

    Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Rats

1958
METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION.
    Cancer research, 1964, Volume: 24

    Topics: Adrenalectomy; Carbon Isotopes; Carcinoma, Hepatocellular; Cortisone; Hypophysectomy; Liver; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; Oxygenases; Phenylalanine; Portacaval Shunt, Surgical; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tryptophan; Tryptophan Oxygenase

1964
RELATION BETWEEN EXPERIMENTAL HEPATOCARCINOGENESIS AND CIRRHOSIS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Amino Alcohols; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver Cirrhosis; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Research; Toxicology

1964
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
    Advances in enzyme regulation, 1963, Volume: 1

    Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; Liver; Liver Neoplasms; Methionine; Methylcholanthrene; Microsomes; Microsomes, Liver; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Polycyclic Compounds; Rats; Research; Zoxazolamine

1963
ETHIONINE CARCINOGENESIS IN THE RAT.
    The Journal of pathology and bacteriology, 1965, Volume: 89

    Topics: Carbon Isotopes; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Ethionine; Glycine; Liver; Liver Neoplasms; Methionine; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; RNA; RNA, Neoplasm; Toxicology

1965
[Synthesis of methionine in presence of homogenates of liver of rats treated with 4-dimethylaminoazobenzene].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Dec-31, Volume: 35

    Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; p-Dimethylaminoazobenzene; Rats

1959
Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.
    Proteomics, 2005, Volume: 5, Issue:18

    Topics: Animals; Apolipoprotein A-I; Carcinoma, Hepatocellular; Chromatography, Liquid; Hepatitis B; Humans; Liver Diseases; Liver Neoplasms; Mass Spectrometry; Methionine; Mice; Neoplasm Proteins; Oxidation-Reduction; Protein Isoforms; Proteome; Tryptophan; Up-Regulation

2005
Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells.
    Cytokine, 2006, Jan-21, Volume: 33, Issue:2

    Topics: Actin Depolymerizing Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoskeletal Proteins; Electron-Transferring Flavoproteins; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Proteins; Gene Expression Profiling; Humans; Interleukin-1; Interleukin-1beta; Interleukin-6; Liver Neoplasms; Membrane Proteins; Methionine; Protein Biosynthesis; Proteins; Sulfur Isotopes; Superoxide Dismutase; Up-Regulation

2006
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Apr-25, Volume: 103, Issue:17

    Topics: Allosteric Regulation; Animals; Carcinoma, Hepatocellular; Cell Line; Cystathionine beta-Synthase; Enzyme Stability; Fatty Liver; Gene Silencing; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Knockout; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine

2006
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas.
    Journal of cellular biochemistry, 2006, Oct-15, Volume: 99, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Diet; Folic Acid Deficiency; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methionine; Microarray Analysis; MicroRNAs; Rats; Rats, Inbred F344

2006
Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.
    International journal of cancer, 2007, Dec-01, Volume: 121, Issue:11

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; DNA Methylation; DNA, Neoplasm; Genes, myc; Genomic Instability; Humans; Immunoblotting; Liver; Liver Neoplasms; Methionine; Mice; Mice, Transgenic; Prognosis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Transforming Growth Factor alpha

2007
Usefulness of 11C-methionine for differentiating tumors from granulomas in experimental rat models: a comparison with 18F-FDG and 18F-FLT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Diagnosis, Differential; Dideoxynucleosides; Fluorodeoxyglucose F18; Granuloma; Inflammation; Liver Neoplasms; Male; Methionine; Mycobacterium bovis; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Turpentine

2008
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Glycine N-Methyltransferase; Histones; Janus Kinases; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice; Mice, Knockout; Promoter Regions, Genetic; ras Proteins; S-Adenosylmethionine; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Transaminases; Tumor Suppressor Proteins

2008
Characterization of nascent and secreted thyroxine-binding globulin in cultured human hepatoma (Hep G2) cells.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Weight; Protein Biosynthesis; Sulfur Radioisotopes; Thyroxine-Binding Proteins

1984
Infusion of branched chain amino acids after partial hepatectomy in man.
    Nutrition and cancer, 1984, Volume: 6, Issue:1

    Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Carcinoma, Hepatocellular; Female; Hepatectomy; Humans; Infusions, Parenteral; Kinetics; Liver Diseases; Liver Neoplasms; Male; Methionine; Middle Aged; Phenylalanine; Tyrosine

1984
Dexamethasone regulates the program of secretory glycoprotein synthesis in hepatoma tissue culture cells.
    The Journal of cell biology, 1980, Volume: 85, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dexamethasone; Fucose; Glycoproteins; Liver; Liver Neoplasms; Membrane Proteins; Methionine; Molecular Weight; Rats

1980
Impaired metabolism of methionine in severe liver diseases. I. Clinical and pathophysiological significance of elevated serum methionine levels.
    Gastroenterologia Japonica, 1982, Volume: 17, Issue:2

    Topics: Amino Acids; Carcinoma, Hepatocellular; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Prognosis

1982
In vitro effects of antitumor antibody--chemotactic factor complexes.
    Clinical immunology and immunopathology, 1982, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Neoplasm; Carbodiimides; Carcinoma, Hepatocellular; Chemotactic Factors; Cytotoxicity, Immunologic; Female; Guinea Pigs; Immunoglobulin G; Interleukin-8; Liver Neoplasms; Macrophages; Male; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neoplasms, Experimental; Oligopeptides; Rabbits

1982
Fibronectin synthesized by a human hepatoma cell line.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Line; Fibronectins; Fluorescent Antibody Technique; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoelectrophoresis, Two-Dimensional; Liver Neoplasms; Methionine; Sulfur Radioisotopes

1984
Human hepatoma cell mutant defective in cell surface protein trafficking.
    The Journal of biological chemistry, 1995, Jul-07, Volume: 270, Issue:27

    Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Biological Transport; Carcinoma, Hepatocellular; Cell Compartmentation; Drug Resistance; Endocytosis; Endosomes; Gene Expression; Humans; Liver Neoplasms; Methionine; Mutation; Orosomucoid; Phenotype; Plant Proteins; Protein Processing, Post-Translational; Receptors, Cell Surface; Ribosome Inactivating Proteins, Type 1; Selection, Genetic; Tumor Cells, Cultured

1995
Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes.
    British journal of cancer, 1995, Volume: 71, Issue:4

    Topics: Amino Acid Sequence; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Cisplatin; Clone Cells; Cytosol; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Humans; KB Cells; Liver Neoplasms; Methionine; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured

1995
Levels of amino acids in human hepatocellular carcinoma and adjacent liver tissue.
    Nutrition and cancer, 1995, Volume: 23, Issue:1

    Topics: Aged; Amino Acids; Carcinoma, Hepatocellular; Cystine; Glycine; Humans; Liver; Liver Neoplasms; Methionine; Middle Aged

1995
Characterization of glutathione efflux from Hep G2 cells.
    Research communications in molecular pathology and pharmacology, 1994, Volume: 85, Issue:3

    Topics: Adenosine Triphosphatases; Carcinoma, Hepatocellular; Cell Line; Epidermal Growth Factor; Glutathione; Humans; Insulin; Liver Neoplasms; Methionine; Potassium Channels; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured

1994
The modulation of apolipoprotein E gene expression by 3,3'-5-triiodothyronine in HepG2 cells occurs at transcriptional and post-transcriptional levels.
    European journal of biochemistry, 1994, Sep-01, Volume: 224, Issue:2

    Topics: Apolipoproteins E; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cycloheximide; Gene Expression Regulation; Humans; Kinetics; Liver Neoplasms; Methionine; Orosomucoid; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured

1994
Biogenesis of the hepatitis B viral middle (M) surface protein in a human hepatoma cell line: demonstration of an alternative secretion pathway.
    The Journal of general virology, 1994, Volume: 75 ( Pt 11)

    Topics: Autoradiography; Base Sequence; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Codon; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glycosylation; Hepatitis B; Hepatitis B virus; Humans; Kinetics; Liver Neoplasms; Methionine; Mutagenesis; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Viral; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins; Virion

1994
Assembly pathway of avian infectious laryngotracheitis virus.
    American journal of veterinary research, 1993, Volume: 54, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Chickens; DNA, Viral; Herpesvirus 2, Gallid; Liver Neoplasms; Marek Disease; Methionine; Microscopy, Electron; Morphogenesis; Thymidine; Tumor Cells, Cultured; Viral Proteins

1993
Retrovirus-mediated gene transfer of transthyretin and transthyretin-methionine 30: a potential tool for the study of amyloidogenesis.
    Neuromuscular disorders : NMD, 1993, Volume: 3, Issue:4

    Topics: 3T3 Cells; Amyloid; Amyloidosis; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line; DNA; Gene Transfer Techniques; Genetic Vectors; Humans; Liver Neoplasms; Methionine; Mice; Molecular Sequence Data; Molecular Weight; Moloney murine leukemia virus; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Polymerase Chain Reaction; Prealbumin; Rats; Repetitive Sequences, Nucleic Acid; Retroviridae; Tumor Cells, Cultured

1993
Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.
    Circulatory shock, 1993, Volume: 40, Issue:3

    Topics: Carcinoma, Hepatocellular; Gene Expression; Heat-Shock Proteins; Hot Temperature; Humans; Kinetics; Liver Neoplasms; Methionine; RNA, Messenger; Sulfur Radioisotopes; Tumor Cells, Cultured

1993
The secretory pathway is normal in dithiothreitol-treated cells, but disulfide-bonded proteins are reduced and reversibly retained in the endoplasmic reticulum.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: alpha 1-Antitrypsin; Asialoglycoprotein Receptor; Asialoglycoproteins; Autoradiography; Calcimycin; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cysteine; Disulfides; Dithiothreitol; Endoplasmic Reticulum; Humans; Liver Neoplasms; Macromolecular Substances; Methionine; Neoplasm Proteins; Oxidation-Reduction; Receptors, Immunologic; Ribonucleases; Serum Albumin; Subcellular Fractions; Sulfur Radioisotopes; Transferrin; Tumor Cells, Cultured

1993
Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells.
    Biochemical and biophysical research communications, 1996, Sep-24, Volume: 226, Issue:3

    Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Humans; Immunoglobulin G; Kinetics; Liver Neoplasms; Methionine; Microsomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1996
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
    Free radical biology & medicine, 1997, Volume: 23, Issue:6

    Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme Oxygenase (Decyclizing); Liver Neoplasms; Male; Methionine; Niacin; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin A; Vitamin E; Vitamin E Deficiency; Vitamins; Weight Gain

1997
Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.
    Journal of lipid research, 1998, Volume: 39, Issue:7

    Topics: Affinity Labels; Animals; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Cattle; Cells, Cultured; Cysteine; Humans; Indoles; Isoindoles; Kinetics; Liver; Liver Neoplasms; Methionine; Microsomes; Microsomes, Liver; Piperidines; Rats; Sulfur Radioisotopes; Triglycerides; Tumor Cells, Cultured; Ultraviolet Rays

1998
Effects of dietary methionine and cystine on lipid metabolism in hepatoma-bearing rats with hyperlipidemia.
    Lipids, 1998, Volume: 33, Issue:9

    Topics: Animals; Bile Acids and Salts; Body Weight; Carcinoma, Hepatocellular; Cholesterol; Cystine; Diet; Eating; Feces; Hyperlipidemias; Lipase; Lipid Metabolism; Lipids; Lipoprotein Lipase; Liver; Male; Methionine; Neoplasm Transplantation; Rats; Sterol Esterase; Triglycerides

1998
Nutritional effects of a D-methionine-containing solution on AH109A hepatoma-bearing rats.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:12

    Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Proteins; Body Weight; Carcinoma, Hepatocellular; Food, Formulated; Liver Neoplasms, Experimental; Male; Methionine; Nutrition Disorders; Nutritional Status; Parenteral Nutrition, Total; Rats; Serum Albumin; Transferrin

1998
Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma.
    Cancer letters, 1999, Feb-08, Volume: 136, Issue:1

    Topics: Arginine; Blotting, Southern; Carcinoma, Hepatocellular; DNA, Neoplasm; Glycine; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Mutation; Threonine

1999
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Carcinoma, Hepatocellular; Enzymes; Humans; Isoenzymes; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; RNA, Messenger

2000
Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2001, Volume: 55, Issue:8

    Topics: Apoptosis; Carcinoma, Hepatocellular; Catalase; Cell Division; DNA Fragmentation; DNA, Neoplasm; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Humans; Hydrogen Peroxide; Malondialdehyde; Methionine; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Transcription Factors; Tumor Cells, Cultured

2001
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:1

    Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12

1975
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylnitrosamine; Esophageal Neoplasms; Folic Acid; Hemangioendothelioma; Lipotropic Agents; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Nicotinic Acids; Nitrosamines; Rats

1977
S-adenosylmethionine:protein methyltransferases in hepatomas.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Adenine; Animals; Arginine; Carcinoma, Hepatocellular; Cell Nucleus; Cytosol; Histones; Liver; Liver Neoplasms; Lysine; Methionine; Methyltransferases; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Rats; Sulfuric Acids

1975
[Diagnosis of primary hepatocellular carcinoma with 99mTc-acetylmethyonine].
    Kaku igaku. The Japanese journal of nuclear medicine, 1975, Volume: 12, Issue:1

    Topics: Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Radionuclide Imaging; Technetium

1975
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
    Nucleic acids research, 1975, Volume: 2, Issue:6

    Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine

1975
Partial purification and characterization of tumor and liver S-adenosylmethionine synthetases.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Female; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasms, Experimental; Phosphates; Rats; Transferases; tRNA Methyltransferases

1977
Labeling of hepatitis B virus surface antigen (HBsAg) synthesized in a HBsAg-producing hepatoma cell line.
    Journal of medical virology, 1979, Volume: 4, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Cystine; Cytoplasm; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Molecular Weight; Peptides; Sulfur Radioisotopes

1979
Specificity of the glutamine-binding site involved in the reguation of glutamine-synthetase activity in hepatoma tissue-culture cells.
    European journal of biochemistry, 1975, Aug-15, Volume: 56, Issue:2

    Topics: Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Diazooxonorleucine; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Methionine; Neoplasms, Experimental; Sulfones

1975
The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins.
    The Journal of biological chemistry, 1992, May-15, Volume: 267, Issue:14

    Topics: Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Humans; Kinetics; Lipoproteins; Liver Neoplasms; Methionine; Protein Biosynthesis; Sulfur Radioisotopes; Transfection

1992
Identification of subcellular compartments involved in biosynthetic processing of cathepsin D.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: alpha 1-Antitrypsin; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Golgi Apparatus; Horseradish Peroxidase; Humans; Kinetics; Liver Neoplasms; Methionine; Protein Processing, Post-Translational; Subcellular Fractions; Sulfur Radioisotopes

1992
The effects of vitamin K1 and warfarin on prothrombin expression in human hepatoblastoma (HepG2) cells.
    Thrombosis and haemostasis, 1992, Jul-06, Volume: 68, Issue:1

    Topics: Antigens; Blotting, Northern; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Nucleic Acid Hybridization; Precipitin Tests; Prothrombin; RNA, Messenger; Sulfur Radioisotopes; Transcription, Genetic; Tumor Cells, Cultured; Vitamin K 1; Warfarin

1992
NF-AB, a liver-specific and cytokine-inducible nuclear factor that interacts with the interleukin-1 response element of the rat alpha 1-acid glycoprotein gene.
    Molecular and cellular biology, 1991, Volume: 11, Issue:6

    Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cytokines; Dexamethasone; Genes; Humans; Interleukin-1; Interleukin-6; Kidney; Kinetics; Liver; Liver Neoplasms; Methionine; Molecular Weight; Nuclear Proteins; Orosomucoid; Protein Binding; Rats; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Transfection

1991
Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetophenones; Carcinoma, Hepatocellular; Cell Survival; Chromatography, Gel; Cycloheximide; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Hydrolysis; Isoflurophate; L-Lactate Dehydrogenase; Liver Neoplasms; Methionine; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Precipitin Tests; Tumor Cells, Cultured

1991
Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells.
    European journal of biochemistry, 1991, Feb-14, Volume: 195, Issue:3

    Topics: Amino Acid Sequence; Autoradiography; Butyrates; Butyric Acid; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Sulfur Radioisotopes

1991
Bromoconduritol treatment delays intracellular transport of secretory glycoproteins in human hepatoma cell cultures.
    Biochemical and biophysical research communications, 1989, Jun-30, Volume: 161, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Cyclohexenes; Glucosidases; Glycoproteins; Humans; Inositol; Kinetics; Liver Neoplasms; Methionine; Neoplasm Proteins; Protein Processing, Post-Translational; Tumor Cells, Cultured

1989
3-Aminobenzamide inhibits poly(ADP ribose) synthetase activity and induces phosphoenolpyruvate carboxykinase (GTP) in H4IIE hepatoma cells.
    Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2

    Topics: Adenosine Diphosphate Ribose; Benzamides; Carcinoma, Hepatocellular; Cyclic AMP; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Immunosorbent Techniques; Liver Neoplasms; Methionine; Phosphoenolpyruvate Carboxykinase (GTP); Poly(ADP-ribose) Polymerase Inhibitors; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured

1988
Regulation of apoprotein synthesis and secretion in the human hepatoma Hep G2. The effect of exogenous lipoprotein.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Apolipoproteins E; Apoproteins; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cholesterol; Chylomicrons; Electrophoresis, Polyacrylamide Gel; Fatty Acids, Nonesterified; Immunosorbent Techniques; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Liposomes; Liver Neoplasms; Methionine; Triglycerides; Tumor Cells, Cultured

1988
Synthesis and secretion of protein C inhibitor by the human hepatoma-derived cell line, Hep G2.
    Biochimica et biophysica acta, 1985, Feb-21, Volume: 844, Issue:2

    Topics: Blood Proteins; Carcinoma, Hepatocellular; Cell Line; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Liver Neoplasms; Methionine; Molecular Weight; Protein C Inhibitor

1985
Synthesis and processing of human serum apolipoprotein AII in vitro and in Hep G2 cells.
    Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:2

    Topics: Amino Acid Sequence; Apolipoprotein A-II; Apolipoproteins A; Carcinoma, Hepatocellular; Cell-Free System; Cells, Cultured; Cysteine; Endoplasmic Reticulum; Humans; Liver; Liver Neoplasms; Methionine; Pancreas; Precipitin Tests; Protein Biosynthesis; RNA, Messenger

1985
Pulse-chase studies of the synthesis of apolipoprotein B in a human hepatoma cell line, Hep G2.
    European journal of biochemistry, 1985, Jun-18, Volume: 149, Issue:3

    Topics: Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Humans; Immunochemistry; Liver Neoplasms; Methionine; Molecular Weight; Peptide Biosynthesis; Sulfur Radioisotopes; Time Factors

1985
Biosynthesis of functionally active heparin cofactor II by a human hepatoma-derived cell line.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Antibody Specificity; Carcinoma, Hepatocellular; Cell Line; Dermatan Sulfate; Glycoproteins; Heparin; Heparin Cofactor II; Humans; Immunoelectrophoresis; Liver Neoplasms; Methionine; Molecular Weight; Thrombin

1985
Enhanced phosphatidylinositol kinase activity is associated with early stages of hepatocarcinogenesis and hepatocellular carcinoma.
    Biochemical and biophysical research communications, 1985, Nov-15, Volume: 132, Issue:3

    Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methionine; Phosphotransferases; Precancerous Conditions; Rats; Rats, Inbred F344

1985
Effect of the antileukemic agent L-asparaginase on thyroxine-binding globulin and albumin synthesis in cultured human hepatoma (HEP G2) cells.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: Asparaginase; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA Replication; Humans; Liver Neoplasms; Methionine; Serum Albumin; Thyroxine-Binding Proteins; Time Factors

1986
Catabolic properties of aglycofibrinogen synthesized by tunicamycin-treated human hepatoma (HepG2) cells and rabbit hepatocytes.
    Biochimica et biophysica acta, 1986, Oct-01, Volume: 883, Issue:3

    Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Fibrinogen; Humans; Hydrolysis; Liver; Liver Neoplasms; Methionine; Oligosaccharides; Rabbits; Tunicamycin

1986
Intracellular modifications of human apolipoprotein E.
    The Journal of biological chemistry, 1986, Oct-15, Volume: 261, Issue:29

    Topics: Apolipoproteins E; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Macrophages; Methionine; Monensin; Monocytes; Sulfur Radioisotopes

1986
Very low and low density lipoprotein synthesis and secretion by the human hepatoma cell line Hep-G2: effects of free fatty acid.
    Journal of lipid research, 1986, Volume: 27, Issue:8

    Topics: Acetates; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Methionine; Mevalonic Acid; Oleic Acid; Oleic Acids; Phospholipids; Serum Albumin, Bovine; Triglycerides

1986
Lipotropic factors and oncogenesis.
    Advances in experimental medicine and biology, 1986, Volume: 206

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Vitamin B 12 Deficiency

1986
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
    Archives of biochemistry and biophysics, 1974, Volume: 165, Issue:2

    Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine

1974
A lipotrope-dependent increase of histidase and urocanase in the livers of choline-deficient rats and in the Reuber H-35 transplanted hepatoma.
    Biochimica et biophysica acta, 1973, Oct-10, Volume: 321, Issue:2

    Topics: Ammonia-Lyases; Animals; Carcinoma, Hepatocellular; Choline; Choline Deficiency; Diet; Histidine Ammonia-Lyase; Hydro-Lyases; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Time Factors; Urocanate Hydratase; Vitamin B 12

1973
S-adenosylmethionine-synthesizing activity of normal and neoplastic mouse tissues.
    Cancer research, 1966, Volume: 26, Issue:12

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Estrogens; Female; Glucosyltransferases; Liver; Liver Neoplasms; Methionine; Mice; Neoplasms, Experimental; Rabbits; Testosterone

1966
Cystathioninuria.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carcinoma, Hepatocellular; Child, Preschool; Cysteine; Diet Therapy; Female; Galactosemias; Glycogen; Humans; Infant; Intellectual Disability; Liver Neoplasms; Male; Maple Syrup Urine Disease; Methionine; Middle Aged; Neuroblastoma; Phenylketonurias; Portal Vein; Pyridoxine; Serine; Sulfisoxazole; Tyrosine

1967
Utilization of L-methionine and S-adenosyl-L-methionine for methylation of soluble RNA by mouse liver and hepatoma extracts.
    Cancer research, 1967, Volume: 27, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Alkylation; Animals; Bacillus subtilis; Carbon Isotopes; Carcinoma, Hepatocellular; Escherichia coli; Female; Fishes; Liver; Liver Neoplasms; Male; Methionine; Mice; Neoplasms, Experimental; Nucleosides; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Tritium; Yeasts

1967
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides

1968
S-adenosylmethionine synthetase activity in some normal rat tissues and transplantable hepatomas.
    Cancer research, 1968, Volume: 28, Issue:12

    Topics: Adenosine Triphosphate; Animals; Brain; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, Paper; Epididymis; Female; Kidney; Liver; Liver Neoplasms; Male; Methionine; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sex Factors; Spectrum Analysis; Testis; Transferases

1968
Studies on DNA methylase activity in mammalian tissue.
    Experientia, 1969, Apr-15, Volume: 25, Issue:4

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Edetic Acid; Liver; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Quaternary Ammonium Compounds; Salmonidae; Testis; Transferases

1969
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
    Journal of molecular biology, 1969, Jun-14, Volume: 42, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine

1969
The distribution and concentration of 75Se-selenomethionine in man.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1969, Volume: 10, Issue:11

    Topics: Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Humans; Liver Neoplasms; Male; Methionine; Radioisotopes; Selenium

1969
Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma.
    Journal of molecular biology, 1969, Volume: 39, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Densitometry; Electrophoresis; Formates; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleotides; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides

1969
Methylation of transfer RNA and of ribosomal RNA in rat liver in the intact animal and the effect of carcinogens.
    Biochimica et biophysica acta, 1969, Dec-16, Volume: 195, Issue:2

    Topics: Aflatoxins; Animals; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Paper; Ethionine; Female; Intestine, Small; Kinetics; Liver; Liver Neoplasms; Male; Methionine; Methylation; Models, Biological; Models, Chemical; Nitrosamines; Nucleotides; Perchlorates; Precancerous Conditions; Protein Biosynthesis; Purinones; Rats; Ribosomes; RNA; RNA, Neoplasm; RNA, Transfer; Stimulation, Chemical; Time Factors

1969
Natural inhibitors of the transfer ribonucleic acid methylases.
    Biochemistry, 1970, Feb-03, Volume: 9, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Dialysis; Drug Stability; Escherichia coli; Female; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Omentum; Pregnancy; Quaternary Ammonium Compounds; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Trypsin; Ultracentrifugation

1970
Development of resistance of Novikoff hepatoma to 5-fluoro-2'-deoxyuridine.
    International journal of cancer, 1970, Sep-15, Volume: 6, Issue:2

    Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Floxuridine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Thymidine; Thymine; Tritium

1970
Methylation of preribosomal and transfer RNA's by isolated nucleoli of the Novikoff rat tumor.
    Biochimica et biophysica acta, 1970, Nov-12, Volume: 224, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Transfer; Tritium

1970
75se-selenomethionine in the scintiscan diignosis of primary hepatocellular carcinoma.
    Gut, 1971, Volume: 12, Issue:4

    Topics: Adenoma, Bile Duct; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methionine; Neoplasm Metastasis; Radionuclide Imaging; Selenium

1971
Methylation of mammalian deoxyribonucleic acid. II. The distribution of 5-methylcytosine in pyrimidine deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1971, Aug-10, Volume: 246, Issue:15

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Techniques; Cytosine; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA, Neoplasm; Formates; Hydrolysis; Liver Neoplasms; Methionine; Methods; Methylation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; Snakes; Spectrophotometry; Thymine Nucleotides; Venoms

1971
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
    Biochimica et biophysica acta, 1971, May-13, Volume: 238, Issue:2

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors

1971
Diagnosis of hepatoma using a multiple radionuclide approach.
    Radiology, 1972, Volume: 102, Issue:2

    Topics: Angiography; Biopsy; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Male; Methionine; Methods; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium; Serum Albumin, Radio-Iodinated; Technetium

1972
Transfer ribonucleic acid methylases of nucleoli isolated from a rat tumor.
    Biochemistry, 1972, Feb-15, Volume: 11, Issue:4

    Topics: Ammonium Chloride; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Escherichia coli; Kinetics; Liver Neoplasms; Magnesium; Methionine; Methyltransferases; Neoplasms, Experimental; Osmolar Concentration; Polynucleotides; Rats; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship; Subcellular Fractions; Tritium

1972
Methylation patterns of transfer RNA from ascites hepatomas.
    Biochimica et biophysica acta, 1972, Jan-18, Volume: 259, Issue:1

    Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine Nucleotides; Guanine Nucleotides; Inosine Nucleotides; Liver; Liver Neoplasms; Methionine; Methylation; Nucleotides; Rats; RNA, Transfer; Tritium; Uracil Nucleotides

1972
Methylation of mammalian deoxyribonucleic acid. 3. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1972, May-10, Volume: 247, Issue:9

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Clone Cells; Cytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Escherichia coli; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats; Spleen; Venoms

1972
Action of ethionine, methionine, ATP, adenine, albumin and Ca 2+ on protein synthesis of normal and tumor cells.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Albumins; Amino Acids; Analysis of Variance; Animals; Calcium; Carbon Isotopes; Carcinoma, Hepatocellular; Cells; Edetic Acid; Ethionine; Female; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; Rats, Inbred Strains

1972
Uptake of 75 Se-selenomethionine by hepatoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1972, Volume: 13, Issue:7

    Topics: Aged; Carcinoma, Hepatocellular; Colloids; Female; Humans; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Sulfur; Technetium

1972
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency

1972
Hepatocellular carcinoma. Clinical and laboratory observations.
    The American journal of gastroenterology, 1972, Volume: 58, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Carcinoma, Hepatocellular; Colloids; Fetal Proteins; Humans; Immunodiffusion; Iodine Radioisotopes; Liver Neoplasms; Male; Methionine; Middle Aged; Radionuclide Imaging; Rose Bengal; Selenium; Sulfur Isotopes; Technetium

1972
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen

1972
[Double hepatic scintigraphy (gold-selenomethionine) in the diagnosis of primary tumors of the liver].
    Medecine & chirurgie digestives, 1972, Volume: 1, Issue:6

    Topics: Carcinoma, Hepatocellular; Gold Isotopes; Humans; Liver Neoplasms; Methionine; Methods; Radionuclide Imaging; Selenium

1972
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine

1973
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
    Cancer research, 1973, Volume: 33, Issue:9

    Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12

1973
[Scintiphotography of primary hepatocellular carcinoma with 75Se-selenomethionine (author's transl)].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1973, Volume: 33, Issue:6

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium

1973
Studies of initiation factors in protein synthesis of host liver and transplantable hepatoma.
    Cancer research, 1974, Volume: 34, Issue:2

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Poly U; Protein Binding; Rats; Ribosomes; RNA, Ribosomal; RNA, Transfer; Transplantation, Homologous

1974
Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.
    Cancer research, 1974, Volume: 34, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Mercaptopurine; Methionine; Neoplasms, Experimental; Nitriles; Pyrimidines; Pyrroles; Ribonucleosides; RNA, Neoplasm; RNA, Ribosomal; Tritium; Uridine

1974
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
    Biochemistry, 1974, Mar-12, Volume: 13, Issue:6

    Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine

1974
The enzymology of methionine metabolism in rat hepatomas.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Dietary Proteins; Liver; Liver Neoplasms; Male; Methionine; Methyltransferases; Neoplasms, Experimental; Rats; Transferases

1974
Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue.
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Aminoisobutyric Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cytosine; DNA; DNA, Neoplasm; Female; Formates; Hepatectomy; Liver Neoplasms; Liver Regeneration; Methionine; Neoplasms, Experimental; Rats; RNA; RNA, Neoplasm; Thymine; Tritium

1974
[A new method for the isotopic diagnosis of primary hepatomas using selenomethionine].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1973, Volume: 54, Issue:11

    Topics: Carcinoma, Hepatocellular; Colloids; Humans; Liver Neoplasms; Methionine; Methods; Neoplasm Metastasis; Radionuclide Imaging; Selenium; Statistics as Topic; Technetium

1973
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
    Cell differentiation, 1972, Volume: 1, Issue:3

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine

1972
Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.
    Cancer research, 1974, Volume: 34, Issue:9

    Topics: Albumins; Animals; Anti-Bacterial Agents; Calcium; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Kinetics; Leucine; Liver; Liver Neoplasms; Magnesium; Methionine; Mitochondria, Liver; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Potassium; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Transplantation, Homologous

1974
The use of multiple radionuclide imaging to differentiate the focal intrahepatic lesion.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1974, Volume: 121, Issue:4

    Topics: Carcinoma, Hepatocellular; Cysts; Hemangioma; Humans; Indium; Isotopes; Liver Abscess; Liver Circulation; Liver Diseases; Liver Neoplasms; Methionine; Radiography; Radioisotopes; Radionuclide Imaging; Selenium

1974
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
    Gan, 1974, Volume: 65, Issue:6

    Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases

1974