Compounds > methionine
Page last updated: 2024-08-17

methionine and Disease Exacerbation

methionine has been researched along with Disease Exacerbation in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's28 (28.28)29.6817
2010's57 (57.58)24.3611
2020's14 (14.14)2.80

Authors

AuthorsStudies
Beppu, T; Fujiwara, S; Iwaya, T; Nomura, JI; Ogasawara, K; Sasaki, T; Sato, Y; Sugai, T; Terasaki, K; Yamada, N1
Bai, M; Chen, J; Dai, H; Han, F; Lin, W; Wang, J; Weng, C; Xie, X; Zhu, H1
Chamberlain, JS; Ferretti, R; Lorena, MDSV; Matsumura, CY; Nagana Gowda, GA; Odom, GL; Santos, EKD1
Arista Romeu, EJ; Campos-Espinosa, A; de la Rosa Vázquez, JM; Escobedo, G; Fabila Bustos, DA; Guzmán, C; Moreno-González, J; Romero-Bello, II; Stolik, S; Valor, A1
Holstein, S; Junker, H; Stope, MB; Venz, S; Walther, R; Zimmermann, U1
Codella, R; Luzi, L; Mollica, G; Montesano, A; Senesi, P; Terruzzi, I; Vacante, F1
Kim, B; Kim, JW; Lim, CW; Qi, J; Zhou, Z1
Choi, SJ; Kim, B; Kim, JW; Lee, K; Lee, SH; Lim, CW; Park, S; Yun, H; Zhou, Z1
Deng, M; Guo, W; Jiang, Y; Ma, P; Ma, S; Mao, C; Nie, L; Sun, J; Sun, L; Wang, N; Xiong, J; Yang, A; Zhang, H1
Chmurzynska, A; Martínez, JA; Milagro, FI; Muzsik, A; Radziejewska, A1
Fu, R; He, Q; Jiang, R; Liu, Y; Lu, Y; Sun, B; Sun, Q; Tian, W; Wang, J; Xu, X; Yu, H; Zhang, Z1
Jagodic, M; Kular, L1
Doskey, CM; Fader, KA; Fling, RR; Nault, R; Zacharewski, TR1
Han, Q; Hoffman, RM1
Lin, K; Lu, J; Ni, J; Tang, H; Wu, G; Zhao, H; Zhu, Y1
Brunet, T; Kohlhase, J; Lotz-Havla, AS; Maier, EM; Regenauer-Vandewiele, S; Schiergens, KA; Weiß, KJ1
Antonelli, A; Benvenga, S; Di Bari, F; Fallahi, P; Ferrari, SM; Vita, R1
Akagi, A; Iwasaki, Y; Kitamoto, T; Mimuro, M; Yamada, M; Yoshida, M1
Alexander, DK; Cho, DY; Grayson, JW; Hill, HS; Lim, DJ; Mackey, C; Peña Garcia, JA; Skinner, D; Weeks, CG; Woodworth, BA; Zhang, S1
Azizi, M; Barreiros, AP; Birklein, F; Emrich, T; Galle, PR; Geber, C; Heise, M; Hoppe-Lotichius, M; Lang, H; Mittler, J; Otto, G; Schad, A; Schmid, JC; Vollmar, J; Weyer, V; Zimmermann, T1
Cao, JL; Li, DQ; Shao, ZM; Sun, R; Xie, HY; Yang, LF; Zhang, FL1
Chandler, JD; Go, YM; Guglani, L; Horati, H; Janssens, HM; Jones, DP; Kilgore, MB; Liu, HK; Margaroli, C; Peng, L; Scholte, BJ; Taurone, AJ; Tiddens, HAWM; Tirouvanziam, R; Uppal, K; Veltman, M1
Ai, D; Cheng, Q; Huang, J; Li, Q; Liu, W; Liu, Y; Wang, C; Wang, H; Yan, J; Yao, L; Ye, C; Zhang, X; Zhu, Y; Zou, Z1
Dong, H; Fan, Y; Hu, X; Li, N; Liu, C1
Camidge, DR; Ching, KA; Christensen, JG; Clark, JW; Diamond, JR; Eckhardt, SG; Kanteti, R; Lira, ME; LoRusso, PM; Salgia, R; Schoenmakers, EF; Varella-Garcia, M; Wilner, K; Xu, LG1
Goto, T; Ikeda, H; Ishibashi, K; Kunihiro, N; Ohata, K; Tsuyuguchi, N1
Ables, GP; Caliendo, NS; Malloy, VL; Mattocks, DA; Orentreich, DS; Orentreich, N; Perrone, CE1
Chan, J; Coelho, T; Conceiçao, I; Cruz, MW; da Silva, AM; Grogan, DR; Kelly, JW; Labaudinière, R; Maia, LF; Packman, J; Planté-Bordeneuve, V; Schmidt, HH; Suhr, OB; Trigo, P1
Beisswenger, PJ; Howell, SK; Mauer, M; Miller, ME; Rich, SS; Russell, G1
Cheng, L; Dai, RW; Luo, ZL; Ren, JD; Tang, LJ; Tian, FZ; Wang, T; Xiang, K1
Angus, PW; Forbes, JM; Goodwin, M; Herath, CB; Jia, Z; Leung, C; Mak, KY; Watt, MJ1
Albano, E; Bena, S; Bozzola, C; Bugianesi, E; Jindal, A; Kusters, D; Locatelli, I; McArthur, S; Parola, M; Paternostro, C; Perretti, M; Reutelingsperger, C; Sutti, S; Vacchiano, M1
Chen, S; Gu, J; Ji, L; Liu, X; Peng, X; Shen, X; Wu, W; Xue, R; Zhang, S1
Cho, EJ; Jang, ES; Kim, CY; Kim, YJ; Kwak, MS; Lee, HS; Lee, JH; Yoon, JH; Yu, SJ1
Chui, PC; Cunniff, JC; Fisher, FM; Flier, JS; Kharitonenkov, A; Lundasen, T; Maratos-Flier, E; Nasser, IA; Popov, Y; Schuppan, D1
Hatanaka, KC; Hirotani, M; Kano, T; Matsushima, M; Minami, N; Nakamichi, K; Nonaka, T; Saijo, M; Sasaki, H; Sasamori, T; Sato, K; Shiga, T; Shimizu, Y; Shirai, S; Takahashi, I; Tanaka, S; Yabe, I1
Brodskaya, ZL; Gurchin, AF; Skvortsova, TY1
Hagiwara, S; Hirai, R; Inoue, T; Ishiwata, K; Ito, K; Kubota, K; Minamimoto, R; Miwa, A; Miyata, Y; Morooka, M; Okasaki, M; Toyohara, J1
Bohle, RM; Gemperlein, K; Haybaeck, J; Kessler, SM; Kiemer, AK; Müller, R; Simon, Y1
Akimoto, T; Alam, MM; Goto, M; Haseba, T; Kitamura, H; Motohashi, H; Ota, N; Shimizu, A; Takano-Yamamoto, T; Yamamoto, M1
Aube, C; Bazeries, P; Boursier, J; Chaigneau, J; Ducluzeau, PH; Fizanne, L; Flamment, M; Leiber, LM; Michalak, S; Moal, V; Roullier, V; Roux, J1
Albano, E; Bozzola, C; Bruzzì, S; Jindal, A; Locatelli, I; Sutti, S; Vacchiano, M1
Adlard, P; Bjurstrom, N; Brandner, S; Caine, D; Collinge, J; Druyeh, R; Hummerich, H; Hyare, H; Jaunmuktane, Z; Lowe, J; Mead, S; Norsworthy, P; Rudge, P; Wadsworth, JD1
Ables, GP; Hens, JR; Nichenametla, SN1
Gu, J; Huang, C; Lin, D; Lin, T; Lin, X; Xie, L; Zheng, S1
Chung, YC; Feierman, E; Kruyer, A; Norris, EH; Richards, A; Strickland, S; Yao, Y1
Choi, KC; Choi, SJ; Kim, B; Kim, JW; Lee, K; Lee, SH; Lim, CW; Park, S; Yun, H1
Agnello, A; Ariviello, R; Bandieramonte, G; Bevilacqua, L; Peroni, M; Simoncini, E; Verdi, P; Zanardi, C1
Dong, ZY; Gao, HF; Gou, LY; Li, AN; Liu, SY; Lou, NN; Su, J; Wu, YL; Xie, Z; Xu, CR; Yan, HH; Yang, JJ; Zhang, XC; Zhong, WZ; Zhou, Q1
Andreu-Serra, H; Buades-Reinés, J; Cisneros-Barroso, E; Gallego-Lezaún, C; Raya-Cruz, M; Ripoll-Vera, T; Usón-Martín, M1
Kaur, S; Overgaard, AJ; Pociot, F1
Barbosa, MR; Cagni, FC; Campêlo, CLDC; Coimbra, DG; Gomes de Andrade, T; Júnior, COG; Júnior, LGO; Neto, ABS; Ribeiro, AM; Silva, RH1
Clahsen, T; Drescher, HK; Hornef, M; Kroy, DC; Noels, H; Sahin, H; Schippers, A; Streetz, KL; Trautwein, C; Wagner, N1
Akao, M; Hibi, T; Irie, R; Miyashita, K; Mizutani, A; Noguchi, M; Ohkura, T; Oike, Y; Sumimoto, H; Suzuki, T; Tabata, M; Taguchi, T; Takayanagi, A; Tamiya, G; Teratani, T; Tomita, K; Yokoyama, H1
Larter, CZ; Yeh, MM1
Cao, Y; Gomez-Hassan, D; Hayman, J; Junck, L; Lawrence, TS; Lee, IH; Piert, M; Rogers, L; Ten Haken, RK; Tsien, C1
Hall, J; Johnstone, EC; Lawrie, SM; McIntosh, AM; McKirdy, J; Mirakhur, A; Moorhead, TW; Stanfield, AC; Sussmann, JE1
Kanayama, M; Kawai, K; Kudo, H; Mann, DA; Morita, S; Nakayama, Y; Oya, T; Sasahara, M; Sugiyama, T; Takahara, T; Yata, Y1
Hare, DL; Zulli, A1
Abdelmalek, M; Choi, SS; Conde-Vancells, J; Diehl, AM; Fearing, CM; Guy, CD; Jung, Y; Karaca, GF; Omenetti, A; Pereira, TA; Syn, WK; Teaberry, V; Wang, J; Witek, RP; Yang, L1
Brunn, A; Deckert, M; Frommolt, P; Heiss, WD; Herholz, K; Jacobs, AH; Kracht, L; Miletic, H; Ullrich, RT1
Ashford, ML; Chowdhry, S; Dillon, JF; Dinkova-Kostova, AT; Hayes, JD; Meakin, PJ; Nazmy, MH; Tsujita, T; Walsh, SV1
Hyodo, I; Ishige, K; Ishii, T; Nakahara, A; Okada, K; Shoda, J; Sugimoto, H; Taguchi, K; Ueda, T; Warabi, E; Yamamoto, M; Yanagawa, T1
Abrial, C; Buc, E; Chollet, P; Durando, X; Farges, MC; Gillet, B; Petorin-Lesens, C; Pezet, D; Thivat, E; Vasson, MP1
Krack, L; Kretzschmar, H; Meissner, B; Redyk, K; Roeber, S; Schmidt, C; von Ahsen, N; Zerr, I1
Bammler, TK; Beyer, RP; Botta, D; Campbell, JS; Fausto, N; Haque, JA; Kavanagh, TJ; McMahan, RS; Montine, TJ; Shimizu-Albergine, M; Wilson, AM; Yeh, MM1
Albanese, A; Bowlus, CL; Devaraj, S; French, SW; Gregory, JF; Halsted, CH; Medici, V; Panacek, EA; Peerson, JM; Rahim, N; Richards, JR; Rossaro, L; Stabler, SP; Virata, MC1
Harada, T; Imada, K; Kajikawa, S; Kawashima, A; Mizuguchi, K; Shimizu, Y; Takeuchi, T1
Liu, WH; Liu, WJ; Ma, LQ; Zhang, KQ; Zhou, W; Zou, CG1
Clarke, CN; Edwards, MJ; Lentsch, AB; Schuster, R; Tevar, AD; Wang, J1
Reynolds, R; Rosner, B; Seddon, JM; Shah, HR1
Allen, RH; Bhowmick, NA; Clark, PE; Koyama, T; Loukachevitch, LV; Luka, Z; Martinez-Ferrer, M; Stabler, S; Wagner, C; Zhao, Z1
Blevins, J; Chen, W; Cohen, M; Cohen, Y; Haldiman, T; Kim, C; Safar, JG; Sy, MS1
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA1
Camporez, JP; Eisenbarth, SC; Elinav, E; Flavell, RA; Gordon, JI; Hao, L; Henao-Mejia, J; Hoffman, HM; Jin, C; Jurczak, MJ; Kau, AL; Mehal, WZ; Shulman, GI; Strowig, T; Thaiss, CA1
Aarseth, JH; Celius, EG; Harbo, HF; Landrø, NI; Lie, BA; Lorentzen, ÅR; Mero, IL; Myhr, KM; Sandvik, L; Smestad, C1
Ebinuma, H; Hatsuse, K; Hibi, T; Hokari, R; Irie, R; Kanai, T; Kurihara, C; Mataki, N; Minamino, T; Miura, S; Nishiyama, K; Okada, Y; Oshikawa, T; Saito, H; Shimamura, K; Shimizu, I; Sugiyama, K; Suzuki, T; Teratani, T; Tomita, K; Yamamoto, J; Yokoyama, H; Yoshida, Y1
Backes, H; Bjerkvig, R; Brekka, N; Hoehn, M; Jacobs, AH; Jikeli, JF; Miletic, H; Monfared, P; Neumaier, B; Niclou, SP; Stieber, D; Talasila, KM; Tavitian, B; Thorsen, F; Viel, T; Waerzeggers, Y; Wang, J; Winkeler, A1
Carmeliet, P; Casteleyn, C; Colle, I; Coulon, S; Geerts, A; Heindryckx, F; Jonckx, B; Leclercq, I; Legry, V; Libbrecht, L; Olievier, K; Stassen, JM; Van Steenkiste, C; Van Vlierberghe, H1
Beguin, YP; Jerusalem, GH1
Fukuyama, Y; Hori, T; Imai, K; Ishii, K; Ishiwata, K; Kubo, O; Maeda, Y; Mutoh, A; Oguni, H; Osawa, M; Saitou, Y; Yamane, F1
Bibby, MC; Blackburn, A; Lucock, MD; Nicolaou, A1
Green, RM; Koppe, SW; Malladi, P; Sahai, A; Whitington, PF1
Bai, YM; Chen, JY; Lai, IC; Liao, DL; Lin, CC; Lin, CY; Liou, YJ; Wang, YC; Yu, SC1
Engler, H; Ribom, D; Schoenmaekers, M; Smits, A1
Baruzzi, A; Capellari, S; Cardone, F; Maras, B; Notari, S; Parchi, P; Pocchiari, M; Schininà, ME; Sità, D1
Alain, T; Auer, IA; Forsyth, P; Luider, JM; Morris, DG; Russell, JA; Stewart, DA; Thirukkumaran, CM1
DeKosky, ST; Desai, P; Kamboh, MI; Nebes, R1
Ribom, D; Smits, A1
Fowler, B1
Arai, T; Hara, K; Honda, H; Hosoi, T; Ito, YM; Kadowaki, T; Kameyama, S; Kitamura, T; Mamun, MR; Ohta, N; Ozeki, T; Sawabe, M; Suzuki, M; Takahashi, S; Takeuchi, T; Yamada, Y; Yanagihara, Y1
Bormans, G; Ceyssens, S; de Groot, T; Goffin, J; Mortelmans, L; Van Laere, K1
Ategbo, JM; Dramane, KL; Girard, A; Hichami, A; Khan, NA; Moutairou, K; Prost, J; Yessoufou, A1
Ikejima, K; Kon, K; Okumura, K; Sato, N; Takei, Y1
Antunes, H; Baldeiras, I; Carpenter, S; Castro, L; Ferreira, C; Machado, A; Magalhães, Z; Ramalheira, J; Ribeiro, MH; Santana, I; Soares, H1
Copple, BL; Gyamfi, M; He, L; Wan, YJ; Wortham, M1
Howard, PM; Mulvihill, A; Naughten, ER; O'Keefe, M; Yap, S1
Koga, T; Nakano, Y; Yoshimura, M1
Blomquist, E; Engler, H; Ribom, D; Smits, A1

Reviews

7 review(s) available for methionine and Disease Exacerbation

ArticleYear
One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.
    Lifestyle genomics, 2020, Volume: 13, Issue:2

    Topics: Animals; Betaine; Carbon; Choline; Disease Progression; Female; Folic Acid; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lipid Metabolism; Liver; Methionine; Microbiota; Models, Genetic; Non-alcoholic Fatty Liver Disease; Nutrients; Polymorphism, Single Nucleotide; Pregnancy; Prenatal Exposure Delayed Effects; Risk

2020
Epigenetic insights into multiple sclerosis disease progression.
    Journal of internal medicine, 2020, Volume: 288, Issue:1

    Topics: Acetylation; Aging; Brain; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Disease Progression; DNA Methylation; Epigenesis, Genetic; Genetic Variation; Genome-Wide Association Study; Histones; Humans; Immunogenetic Phenomena; Life Style; Methionine; Multiple Sclerosis; Oligodendroglia; Quantitative Trait Loci; Signal Transduction; Tobacco Smoke Pollution

2020
Methionine restriction beyond life-span extension.
    Annals of the New York Academy of Sciences, 2016, Volume: 1363

    Topics: Adiposity; Animals; Bone and Bones; Caloric Restriction; Diet; Disease Progression; Epigenesis, Genetic; Glucose; Humans; Life Expectancy; Lipid Metabolism; Liver; Methionine; Myocardium; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2016
Metabolomic Biomarkers in the Progression to Type 1 Diabetes.
    Current diabetes reports, 2016, Volume: 16, Issue:12

    Topics: Autoimmunity; Biomarkers; Diabetes Mellitus, Type 1; Disease Progression; Humans; Metabolomics; Methionine; Triglycerides

2016
Animal models of NASH: getting both pathology and metabolic context right.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:11

    Topics: Animals; Choline Deficiency; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Disease Progression; Fatty Liver; Genetic Predisposition to Disease; Hyperphagia; Intubation, Gastrointestinal; Liver; Methionine; Overnutrition; Phenotype; Reproducibility of Results

2008
Positron emission tomography in non-Hodgkin's lymphoma (NHL): relationship between tracer uptake and pathological findings, including preliminary experience in the staging of low-grade NHL.
    Clinical lymphoma, 2002, Volume: 3, Issue:1

    Topics: Carbon Radioisotopes; Cell Division; Disease Progression; Fluorodeoxyglucose F18; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Methionine; Neoplasm Staging; Prognosis; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed

2002
Homocysteine: overview of biochemistry, molecular biology, and role in disease processes.
    Seminars in vascular medicine, 2005, Volume: 5, Issue:2

    Topics: Animals; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Oxidation-Reduction

2005

Trials

5 trial(s) available for methionine and Disease Exacerbation

ArticleYear
Lowering and Stabilizing PSA Levels in Advanced-prostate Cancer Patients With Oral Methioninase.
    Anticancer research, 2021, Volume: 41, Issue:4

    Topics: Administration, Oral; Aged, 80 and over; Bone Neoplasms; Carbon-Sulfur Lyases; Disease Progression; Down-Regulation; Enzyme Replacement Therapy; Humans; Male; Methionine; Middle Aged; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Proteins

2021
Myo-inositol and selenium reduce the risk of developing overt hypothyroidism in patients with autoimmune thyroiditis.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:2 Suppl

    Topics: Autoantibodies; Chemokine CXCL10; Disease Progression; Drug Therapy, Combination; Female; Humans; Hypothyroidism; Inositol; Male; Methionine; Middle Aged; Organoselenium Compounds; Selenium; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin

2017
Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy.
    Journal of neurology, 2013, Volume: 260, Issue:11

    Topics: Adult; Aged; Amyloid Neuropathies, Familial; Benzoxazoles; Disease Progression; Drug Administration Schedule; Female; Follow-Up Studies; Humans; International Cooperation; Male; Methionine; Middle Aged; Mutation; Prealbumin; Quality of Life; Time Factors; Valine; Young Adult

2013
Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; Glioblastoma; Humans; Magnetic Resonance Imaging; Methionine; Middle Aged; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Retreatment; Software; Temozolomide; Treatment Failure; Young Adult

2009
Dietary methionine restriction with FOLFOX regimen as first line therapy of metastatic colorectal cancer: a feasibility study.
    Oncology, 2010, Volume: 78, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diet; Disease Progression; Feasibility Studies; Female; Fluorouracil; Humans; Leucovorin; Male; Methionine; Middle Aged; Models, Statistical; Monitoring, Physiologic; Neoplasm Metastasis; Organoplatinum Compounds; Treatment Outcome

2010

Other Studies

87 other study(ies) available for methionine and Disease Exacerbation

ArticleYear
PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma.
    Clinical nuclear medicine, 2022, Jul-01, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Chemotherapy, Adjuvant; Disease Progression; DNA Methylation; Glioma; Humans; Isocitrate Dehydrogenase; Methionine; Neoplasm Recurrence, Local; Positron-Emission Tomography; Temozolomide

2022
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
    Nutrients, 2022, Aug-15, Volume: 14, Issue:16

    Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine

2022
Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle.
    Skeletal muscle, 2023, 09-13, Volume: 13, Issue:1

    Topics: Acetic Acid; Alanine; Animals; Creatine; Disease Progression; Glycerol; Isoleucine; Methionine; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Duchenne; Phosphocreatine; Racemethionine; Tumor Necrosis Factor-alpha

2023
Study of Methionine Choline Deficient Diet-Induced Steatosis in Mice Using Endogenous Fluorescence Spectroscopy.
    Molecules (Basel, Switzerland), 2019, Aug-29, Volume: 24, Issue:17

    Topics: Adipose Tissue; Animals; Area Under Curve; Choline Deficiency; Discriminant Analysis; Disease Models, Animal; Disease Progression; Humans; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Principal Component Analysis; ROC Curve; Sensitivity and Specificity; Severity of Illness Index; Spectrometry, Fluorescence

2019
Nicotinamide
    Anticancer research, 2019, Volume: 39, Issue:10

    Topics: Biomarkers, Tumor; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Disease Progression; HEK293 Cells; Humans; Interleukin-6; Kidney Neoplasms; Methionine; Nicotinamide N-Methyltransferase; Prognosis; Up-Regulation

2019
L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:3

    Topics: Animals; Carnitine; Choline Deficiency; Diet; Dietary Supplements; Disease Models, Animal; Disease Progression; Heart Diseases; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species

2020
Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation-Mediated Cell Death in Mice.
    The American journal of pathology, 2020, Volume: 190, Issue:1

    Topics: Animals; Apoptosis; Cell Death; Choline Deficiency; Diet; Disease Progression; Ferroptosis; Inflammation; Lipid Peroxidation; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase

2020
Cigarette smoking differentially regulates inflammatory responses in a mouse model of nonalcoholic steatohepatitis depending on exposure time point.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 135

    Topics: Animals; Body Weight; Choline Deficiency; Cigarette Smoking; Cytokines; Diet, High-Fat; Disease Progression; Inflammation; Liver; Liver Cirrhosis; Macrophages; Male; Methionine; Mice, Inbred C57BL; Monocytes; Non-alcoholic Fatty Liver Disease; Organ Size; PPAR gamma; Time Factors

2020
Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway.
    Journal of molecular and cellular cardiology, 2020, Volume: 138

    Topics: Animals; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Diet; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Foam Cells; HEK293 Cells; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Plaque, Atherosclerotic; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Sp1 Transcription Factor; THP-1 Cells

2020
ARRB1 inhibits non-alcoholic steatohepatitis progression by promoting GDF15 maturation.
    Journal of hepatology, 2020, Volume: 72, Issue:5

    Topics: Adult; Animals; beta-Arrestin 1; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Disease Progression; Female; Golgi Apparatus; Growth Differentiation Factor 15; Humans; Lipogenesis; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Non-alcoholic Fatty Liver Disease; Signal Transduction; Young Adult

2020
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice.
    Scientific reports, 2020, 09-09, Volume: 10, Issue:1

    Topics: Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Disease Progression; Fibrosis; Folic Acid; Glycine N-Methyltransferase; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polychlorinated Dibenzodioxins

2020
Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 12, Issue:2

    Topics: Animals; Caspases, Initiator; Choline; Diet; Disease Progression; Hepatocytes; Inflammation; Lipopolysaccharides; Liver; Methionine; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Pyroptosis; Signal Transduction; Up-Regulation

2021
Subcutaneous vitamin B12 administration using a portable infusion pump in cobalamin-related remethylation disorders: a gentle and easy to use alternative to intramuscular injections.
    Orphanet journal of rare diseases, 2021, 05-12, Volume: 16, Issue:1

    Topics: Child; Disease Progression; Humans; Infusion Pumps; Injections, Intramuscular; Methionine; Vitamin B 12

2021
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
    Prion, 2018, 01-02, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine

2018
l-Methionine anti-biofilm activity against Pseudomonas aeruginosa is enhanced by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor.
    International forum of allergy & rhinology, 2018, Volume: 8, Issue:5

    Topics: Aminophenols; Anti-Bacterial Agents; Biofilms; Chronic Disease; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Progression; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Methionine; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Rhinitis; Sinusitis

2018
Progression of transthyretin (TTR) amyloidosis in donors and recipients after domino liver transplantation-a prospective single-center cohort study.
    Transplant international : official journal of the European Society for Organ Transplantation, 2018, Volume: 31, Issue:11

    Topics: Adult; Aged; Amyloid Neuropathies, Familial; Biopsy; Child; Databases, Factual; Disease Progression; Echocardiography; Female; Heart Rate; Humans; Liver Failure; Liver Transplantation; Living Donors; Male; Methionine; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome; Valine

2018
Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer.
    Cancer research, 2018, 10-15, Volume: 78, Issue:20

    Topics: Alternative Splicing; Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Exons; Female; Heterogeneous-Nuclear Ribonucleoprotein Group M; Humans; Hyaluronan Receptors; Isoleucine; Methionine; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Isoforms; Transcription Factors; Triple Negative Breast Neoplasms

2018
Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.
    The European respiratory journal, 2018, Volume: 52, Issue:4

    Topics: Bronchiectasis; Bronchoalveolar Lavage Fluid; Bronchoscopy; Child, Preschool; Cystic Fibrosis; Disease Progression; Female; Humans; Infant; Lung; Male; Methionine; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Prospective Studies; Tomography, X-Ray Computed

2018
Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis.
    Cellular and molecular gastroenterology and hepatology, 2019, Volume: 7, Issue:1

    Topics: Animals; Apoptosis; Calcium; Cholesterol; Choline; Diet; Disease Progression; Dynamins; Feeding Behavior; Fructose; Gene Deletion; GTP Phosphohydrolases; Hepatocytes; Humans; Inflammation; Lipolysis; Liver; Lysosomes; Macrophages, Peritoneal; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Palmitates; Phagosomes; Phosphorylation; Phosphoserine; Regulatory-Associated Protein of mTOR

2019
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
    Journal of vascular research, 2019, Volume: 56, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Glycine N-Methyltransferase; Interleukin-6; Male; Matrix Metalloproteinase 2; Methionine; Osteopontin; Pancreatic Elastase; Rats, Sprague-Dawley; Risk Factors; Time Factors

2019
Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-01, Volume: 31, Issue:16

    Topics: Antineoplastic Agents; Biopsy; Carcinoma, Renal Cell; Disease Progression; Drug Resistance, Neoplasm; Heterozygote; Humans; In Situ Hybridization, Fluorescence; Kidney Neoplasms; Male; Methionine; Middle Aged; Point Mutation; Proto-Oncogene Proteins c-met; Pyrazines; Receptor Protein-Tyrosine Kinases; Sequence Analysis, DNA; Threonine; Treatment Failure; Triazoles

2013
Analysis of progression and recurrence of meningioma using (11)C-methionine PET.
    Annals of nuclear medicine, 2013, Volume: 27, Issue:8

    Topics: Adult; Aged; Disease Progression; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Methionine; Middle Aged; Positron-Emission Tomography; Recurrence; Retrospective Studies; Risk Factors; ROC Curve; Young Adult

2013
Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Blood Glucose; Diet; Disease Progression; Fatty Acids; Fatty Liver; Gene Expression Regulation; Homeostasis; Inflammation; Insulin; Leptin; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Methionine; Mice; Mice, Obese; Obesity; Oxidation-Reduction; Severity of Illness Index; Triglycerides

2013
Detection of diabetic nephropathy from advanced glycation endproducts (AGEs) differs in plasma and urine, and is dependent on the method of preparation.
    Amino acids, 2014, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Child; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progression; Glomerular Basement Membrane; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Methionine; Specimen Handling; Young Adult

2014
Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:1

    Topics: Animals; Choline Deficiency; Cytochrome P-450 CYP2E1; Disease Models, Animal; Disease Progression; Fatty Liver; Heme Oxygenase-1; Hydrogen Sulfide; Inflammation; Interleukin-6; Liver; Male; Methionine; Mitochondria, Liver; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2014
Dietary glycotoxins exacerbate progression of experimental fatty liver disease.
    Journal of hepatology, 2014, Volume: 60, Issue:4

    Topics: Animals; Cell Proliferation; Choline Deficiency; Diet; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hepatic Stellate Cells; Insulin Resistance; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Rats, Sprague-Dawley

2014
Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:2

    Topics: Animals; Annexin A1; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity

2014
Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis.
    Biochemical and biophysical research communications, 2014, May-23, Volume: 448, Issue:1

    Topics: Animals; Bile Acids and Salts; Cholestasis, Intrahepatic; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear

2014
Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:7

    Topics: Animal Feed; Animals; Apoptosis; Biomarkers; Choline Deficiency; Disease Progression; Drug Administration Schedule; Endoplasmic Reticulum Stress; Fatty Liver; Gastrointestinal Agents; Immunoblotting; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Taurochenodeoxycholic Acid

2014
Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets.
    Gastroenterology, 2014, Volume: 147, Issue:5

    Topics: Animals; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Acids; Fibroblast Growth Factors; Hepatitis; Inflammation Mediators; Infusions, Subcutaneous; Lipid Peroxidation; Liver; Liver Cirrhosis; Methionine; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Recombinant Proteins; RNA, Messenger; Severity of Illness Index; Time Factors

2014
Usefulness of 11C-methionine-positron emission tomography for the diagnosis of progressive multifocal leukoencephalopathy.
    Journal of neurology, 2014, Volume: 261, Issue:12

    Topics: Aged; Aged, 80 and over; Antimalarials; Brain; Disease Progression; Early Diagnosis; Female; Fluorodeoxyglucose F18; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Mefloquine; Methionine; Middle Aged; Positron-Emission Tomography; Prognosis; Treatment Outcome

2014
[PET using 11C-methionine in recognition of pseudoprogression in cerebral glioma after combined treatment].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2014, Volume: 78, Issue:4

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Disease Progression; Female; Glioma; Humans; Male; Methionine; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals

2014
Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma.
    Annals of nuclear medicine, 2015, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow; Carbon Radioisotopes; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Male; Methionine; Middle Aged; Multimodal Imaging; Multiple Myeloma; Plasmacytoma; Positron-Emission Tomography; Radiopharmaceuticals; Thionucleosides; Thymidine; Tomography, X-Ray Computed; Whole Body Imaging

2015
Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.
    World journal of gastroenterology, 2014, Dec-21, Volume: 20, Issue:47

    Topics: Animals; Cholesterol; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Acids; Female; Inflammation Mediators; Iron; Lipid Peroxidation; Liver; Male; Methionine; Mice, Transgenic; Non-alcoholic Fatty Liver Disease; RNA-Binding Proteins; Time Factors; Up-Regulation

2014
Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.
    Genes to cells : devoted to molecular & cellular mechanisms, 2015, Volume: 20, Issue:6

    Topics: Alcohol Dehydrogenase; Animals; Choline Deficiency; Diet; Disease Progression; Fatty Liver; Glutathione; Lipid Metabolism; Liver; Methionine; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease

2015
MRI versus histological methods for time course monitoring of steatosis amount in a murine model of NAFLD.
    Diagnostic and interventional imaging, 2015, Volume: 96, Issue:9

    Topics: Adipose Tissue; Animals; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Humans; Image Interpretation, Computer-Assisted; Liver; Magnetic Resonance Imaging; Methionine; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Statistics as Topic; Triglycerides

2015
CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:9

    Topics: Actins; Animals; Antigens, Differentiation; Antigens, Ly; CD11b Antigen; Choline Deficiency; CX3C Chemokine Receptor 1; Dendritic Cells; Diet; Disease Progression; Flow Cytometry; Gene Expression; Immunohistochemistry; Inflammation; Liver; Methionine; Mice, Inbred C57BL; Monocytes; Non-alcoholic Fatty Liver Disease; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; Sulfides; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2015
Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 11

    Topics: Adult; Brain; Codon; Creutzfeldt-Jakob Syndrome; Disease Progression; Drug Contamination; Electroencephalography; Female; Gene-Environment Interaction; Genotype; Growth Disorders; Homozygote; Human Growth Hormone; Humans; Iatrogenic Disease; Infectious Disease Incubation Period; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Prion Proteins; Prions; Retrospective Studies; Time Factors; United Kingdom; Valine

2015
(1)H NMR-Based Analysis of Serum Metabolites in Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats.
    Disease markers, 2016, Volume: 2016

    Topics: Animals; Arterial Pressure; Disease Models, Animal; Disease Progression; Energy Metabolism; Glycolysis; Hypertension, Pulmonary; Lipid Metabolism; Male; Metabolome; Methionine; Monocrotaline; Proton Magnetic Resonance Spectroscopy; Pulmonary Artery; Rats; Rats, Sprague-Dawley

2016
Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biotinylation; Brain; Cerebral Amyloid Angiopathy; Dementia, Vascular; Disease Models, Animal; Disease Progression; Fibrin; Fibrinogen; Fibrinolysis; Humans; Hyperhomocysteinemia; Immunohistochemistry; Maze Learning; Memory; Methionine; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Binding

2016
Mainstream cigarette smoke accelerates the progression of nonalcoholic steatohepatitis by modulating Kupffer cell-mediated hepatocellular apoptosis in adolescent mice.
    Toxicology letters, 2016, Aug-10, Volume: 256

    Topics: Age Factors; Animals; Apoptosis; Cells, Cultured; Choline Deficiency; Cytokines; Disease Models, Animal; Disease Progression; Hepatocytes; Inflammation Mediators; Kupffer Cells; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Paracrine Communication; Severity of Illness Index; Signal Transduction; Smoke; Smoking; Time Factors

2016
Infezioni virali in ginecologia: un problema risolto?
    Minerva ginecologica, 2016, Volume: 68, Issue:3

    Topics: Adult; Antioxidants; Carcinoma, Squamous Cell; Disease Progression; Echinacea; Female; Follow-Up Studies; Humans; Italy; Methionine; Middle Aged; Papanicolaou Test; Papillomaviridae; Papillomavirus Infections; Probiotics; Retrospective Studies; Treatment Outcome; Uterine Cervical Dysplasia; Vaginal Smears

2016
The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer.
    Oncotarget, 2016, Aug-09, Volume: 7, Issue:32

    Topics: Adult; Aged; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Threonine; Up-Regulation; Young Adult

2016
Transthyretin familial amyloid polyneuropathy (TTR-FAP) in Mallorca: a comparison between late- and early-onset disease.
    Journal of the peripheral nervous system : JPNS, 2016, Volume: 21, Issue:4

    Topics: Adult; Age of Onset; Aged; Amyloid Neuropathies, Familial; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methionine; Middle Aged; Mutation; Prealbumin; Retrospective Studies; Spain; Valine; Young Adult

2016
Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.
    The Journal of neuropsychiatry and clinical neurosciences, 2017,Spring, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Brain-Derived Neurotrophic Factor; Depression; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Valine

2017
β
    Journal of hepatology, 2017, Volume: 66, Issue:6

    Topics: Animals; Cell Adhesion Molecules; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Disease Progression; Integrin beta Chains; Liver; Lymphocyte Subsets; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucoproteins; Non-alcoholic Fatty Liver Disease; Oxidative Stress

2017
Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:2

    Topics: Animals; Catalase; Cells, Cultured; Choline Deficiency; Diet; Disease Progression; Enzyme Activation; Fatty Liver; Gene Transfer Techniques; Hepatocytes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; PPAR alpha; Reactive Oxygen Species; Receptors, Adiponectin; Signal Transduction; Transforming Growth Factor beta1

2008
Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant.
    Biological psychiatry, 2009, Aug-01, Volume: 66, Issue:3

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Progression; Electronic Data Processing; Female; Gene Frequency; Genotype; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Single Nucleotide; Prefrontal Cortex; Valine

2009
Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:7

    Topics: Adipocytes; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cell Line; Cell Size; Chemokine CCL2; Choline Deficiency; Collagen Type I; Disease Models, Animal; Disease Progression; Drinking; Eating; Fatty Liver; Intra-Abdominal Fat; Liver; Liver Cirrhosis; Macrophages; Male; Methionine; Mice; Mice, Inbred C57BL; Organ Size; Oxidative Stress; Receptors, CCR2; RNA, Messenger; Telmisartan; Transforming Growth Factor beta1; Triglycerides

2009
High dietary methionine plus cholesterol stimulates early atherosclerosis and late fibrous cap development which is associated with a decrease in GRP78 positive plaque cells.
    International journal of experimental pathology, 2009, Volume: 90, Issue:3

    Topics: Animals; Aorta, Abdominal; Atherosclerosis; Cholesterol; Cholesterol, Dietary; Coronary Artery Disease; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Endoplasmic Reticulum Chaperone BiP; Endothelium, Vascular; Heat-Shock Proteins; Male; Methionine; Organ Culture Techniques; Rabbits

2009
Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.
    Gastroenterology, 2009, Volume: 137, Issue:4

    Topics: Animals; Case-Control Studies; Cell Line; Cell Transdifferentiation; Choline Deficiency; Disease Progression; Epithelial Cells; Fatty Liver; Fibroblasts; Hedgehog Proteins; Humans; Liver Cirrhosis, Experimental; Methionine; Mice; Mice, Inbred C57BL; Patched Receptors; Patched-1 Receptor; Rats; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Signal Transduction; Veratrum Alkaloids

2009
Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:12

    Topics: Adolescent; Adult; Biological Transport; Child; Disease Progression; Female; Glioma; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Positron-Emission Tomography; Retrospective Studies; Tomography, X-Ray Computed; Young Adult

2009
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis.
    Free radical biology & medicine, 2010, Jan-15, Volume: 48, Issue:2

    Topics: Animals; Choline; Cyclooxygenase 2; Disease Progression; Fatty Liver; Food, Formulated; Interleukin-1beta; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Tumor Necrosis Factor-alpha

2010
Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:2

    Topics: Animal Feed; Animals; Choline; Choline Deficiency; Disease Progression; Fatty Liver; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; RNA, Messenger

2010
Clinical features of rapidly progressive Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2010, Volume: 29, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Apolipoproteins E; Biomarkers; Codon; Disease Progression; Female; Gait; Gene Frequency; Heterozygote; Homozygote; Humans; Male; Methionine; Middle Aged; Muscle Rigidity; Myoclonus; Peptide Fragments; Polymorphism, Genetic; Prion Proteins; Prions; Retrospective Studies; Survival Analysis; tau Proteins; Time Factors; Valine

2010
Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:12

    Topics: Acyl Coenzyme A; Acyl-CoA Oxidase; Animals; Antioxidants; Carnitine O-Palmitoyltransferase; Choline; Diet; Disease Progression; Fatty Liver; Glutathione; Hepatocytes; Inflammation; Ion Channels; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Oxidative Stress; Uncoupling Protein 2

2010
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease.
    Journal of hepatology, 2010, Volume: 53, Issue:3

    Topics: Adult; Aged; Alcoholism; Aminobutyrates; Biomarkers; Case-Control Studies; Cystathionine; Disease Progression; Female; Homocysteine; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Methionine; Middle Aged; Sulfur; Young Adult

2010
Eicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:4

    Topics: Actins; Animals; Choline Deficiency; Connective Tissue Growth Factor; Disease Progression; Eicosapentaenoic Acid; Fatty Liver; Liver; Liver Cirrhosis; Male; Methionine; Non-alcoholic Fatty Liver Disease; Procollagen; Rats; Rats, Wistar; Reactive Oxygen Species; Transforming Growth Factor beta1; Treatment Outcome; Triglycerides

2011
Inhibition of hepatic glycogen synthesis by hyperhomocysteinemia mediated by TRB3.
    The American journal of pathology, 2011, Volume: 178, Issue:4

    Topics: Animals; Cell Cycle Proteins; Disease Progression; Glycogen; Homocysteine; Humans; Hyperhomocysteinemia; Indoles; Insulin Resistance; Liver Glycogen; Methionine; Mice; Phosphorylation; PPAR gamma; Protein Serine-Threonine Kinases; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering

2011
The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis.
    The Journal of surgical research, 2011, Volume: 169, Issue:1

    Topics: Alanine Transaminase; Animals; Diet; Disease Models, Animal; Disease Progression; Fatty Liver; Ischemia; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Peroxidase; Reperfusion Injury

2011
Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications.
    Ophthalmology, 2011, Volume: 118, Issue:7

    Topics: Behavior; Betaine; Diet; Disease Progression; Epigenomics; Humans; Macular Degeneration; Male; Methionine; Nutritional Physiological Phenomena; Phenotype; Retinal Drusen; Severity of Illness Index; Smoking; Twins, Monozygotic; Vitamin D

2011
Serum methionine metabolites are risk factors for metastatic prostate cancer progression.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Biomarkers, Tumor; Disease Progression; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Methionine; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Prostatic Neoplasms; Recurrence; Risk Factors; ROC Curve

2011
Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.
    PLoS pathogens, 2011, Volume: 7, Issue:9

    Topics: Aged; Aged, 80 and over; Brain; Codon; Creutzfeldt-Jakob Syndrome; Disease Progression; Epitopes; Female; Homozygote; Humans; Male; Methionine; Middle Aged; Nonlinear Dynamics; Peptide Hydrolases; Phenotype; Prion Proteins; Prions; PrPSc Proteins; Regression Analysis; Valine

2011
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6

2012
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
    Nature, 2012, Feb-01, Volume: 482, Issue:7384

    Topics: Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Choline; Colon; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Fatty Liver; Inflammasomes; Inflammation; Interleukin-18; Male; Metagenome; Methionine; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Obesity; Receptors, Cell Surface; RNA, Ribosomal, 16S; Toll-Like Receptor 4; Toll-Like Receptor 9; Tumor Necrosis Factor-alpha

2012
Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course.
    Journal of neuroimmunology, 2012, Volume: 244, Issue:1-2

    Topics: Adult; Age of Onset; Brain-Derived Neurotrophic Factor; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Methionine; Multiple Sclerosis; Norway; Polymorphism, Genetic; Valine

2012
p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.
    Journal of hepatology, 2012, Volume: 57, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Choline Deficiency; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatocytes; Humans; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Primary Cell Culture; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; RNA, Messenger; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transforming Growth Factor beta; Tumor Suppressor Protein p53; Up-Regulation

2012
Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:7

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Data Interpretation, Statistical; Dideoxynucleosides; Disease Progression; Fluorodeoxyglucose F18; Glioblastoma; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Ki-67 Antigen; Magnetic Resonance Imaging; Methionine; Neoplasm Transplantation; Neovascularization, Pathologic; Paraffin Embedding; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Nude; Xenograft Model Antitumor Assays

2012
Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Choline Deficiency; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Hepatocytes; In Vitro Techniques; Lipid Metabolism; Liver; Methionine; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Neovascularization, Pathologic; Non-alcoholic Fatty Liver Disease; Placenta Growth Factor; Pregnancy Proteins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2013
Rasmussen syndrome: multifocal spread of inflammation suggested from MRI and PET findings.
    Epilepsia, 2003, Volume: 44, Issue:8

    Topics: Autonomic Nervous System Diseases; Carbon Radioisotopes; Cerebral Cortex; Child; Disease Progression; Dominance, Cerebral; Encephalitis; Epilepsia Partialis Continua; Epilepsy; Epilepsy, Partial, Motor; Epilepsy, Temporal Lobe; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Image Enhancement; Magnetic Resonance Imaging; Methionine; Occipital Lobe; Temporal Lobe; Tomography, Emission-Computed

2003
Temporal evaluation of methionine synthase and related metabolites in the MAC15A mouse adenocarcinoma animal model.
    International journal of cancer, 2004, Nov-20, Volume: 112, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma; Cell Division; Disease Models, Animal; Disease Progression; Humans; Methionine; Methylation; Mice

2004
Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Alanine Transaminase; Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Progression; Fatty Liver; Female; Glutathione; Hepatitis; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Pentoxifylline; Phosphodiesterase Inhibitors; RNA, Messenger; Triglycerides; Tumor Necrosis Factor-alpha

2004
Negative association between catechol-O-methyltransferase (COMT) gene Val158Met polymorphism and persistent tardive dyskinesia in schizophrenia.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:8

    Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Brain Chemistry; Catechol O-Methyltransferase; Cohort Studies; Disease Progression; DNA Mutational Analysis; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Genetic; Schizophrenia; Valine

2005
Evaluation of 11C-methionine PET as a surrogate endpoint after treatment of grade 2 gliomas.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Carbon Isotopes; Cell Proliferation; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Glioma; Humans; Male; Methionine; Middle Aged; Outcome Assessment, Health Care; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Retrospective Studies; Supratentorial Neoplasms

2005
Creutzfeldt-Jakob disease associated with the R208H mutation in the prion protein gene.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: 14-3-3 Proteins; Amino Acid Substitution; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; DNA Mutational Analysis; Fatal Outcome; Female; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Immunoblotting; Immunohistochemistry; Mass Spectrometry; Methionine; Middle Aged; Mutation; Neurons; Phenotype; PrPSc Proteins

2005
Biological purging of breast cancer cell lines using a replication-competent oncolytic virus in human stem cell autografts.
    Bone marrow transplantation, 2005, Volume: 35, Issue:11

    Topics: Antigens, CD34; Blood Component Removal; Bone Marrow Purging; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Disease-Free Survival; DNA Fragmentation; Flow Cytometry; Hematopoietic Stem Cells; Humans; Immunohistochemistry; Immunoprecipitation; Leukocyte Common Antigens; Methionine; Stem Cell Transplantation; Time Factors; Transplantation, Autologous; Treatment Outcome; Viruses

2005
Investigation of the effect of brain-derived neurotrophic factor (BDNF) polymorphisms on the risk of late-onset Alzheimer's disease (AD) and quantitative measures of AD progression.
    Neuroscience letters, 2005, May-13, Volume: 379, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Black People; Brain-Derived Neurotrophic Factor; Case-Control Studies; Disease Progression; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Polymorphism, Genetic; Risk; Valine; White People

2005
Baseline 11C-methionine PET reflects the natural course of grade 2 oligodendrogliomas.
    Neurological research, 2005, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Oligodendroglia; Positron-Emission Tomography; Predictive Value of Tests; Retrospective Studies; Time Factors

2005
The Val158Met polymorphism of the catechol-O-methyltransferase gene is associated with the PSA-progression-free survival in prostate cancer patients treated with estramustine phosphate.
    European urology, 2005, Volume: 48, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Catechol O-Methyltransferase; Disease Progression; Disease-Free Survival; Estramustine; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Genetic; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms; Valine

2005
[11C]methionine PET, histopathology, and survival in primary brain tumors and recurrence.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Carbon Radioisotopes; Child; Child, Preschool; Disease Progression; Female; Forecasting; Glioma; Humans; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oligodendroglioma; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies; Survival Rate

2006
Cassava-enriched diet is not diabetogenic rather it aggravates diabetes in rats.
    Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Cyanides; Diabetes Mellitus, Experimental; Diet; Disease Progression; Erythrocytes; Insulin; Male; Manihot; Methionine; Rats; Rats, Wistar

2006
Role of adipocytokines in hepatic fibrogenesis.
    Journal of gastroenterology and hepatology, 2007, Volume: 22 Suppl 1

    Topics: Adiponectin; Animals; Choline Deficiency; Disease Models, Animal; Disease Progression; Fatty Liver; Kupffer Cells; Leptin; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Oxidative Stress; Transforming Growth Factor beta1; Up-Regulation

2007
Variant Creutzfeldt-Jakob [corrected] disease: the second case in Portugal and in the same geographical region.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:2

    Topics: Adolescent; Brain; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Disease Outbreaks; Disease Progression; Fatal Outcome; Female; Homozygote; Humans; Methionine; Neurologic Examination; Neuropsychological Tests; Topography, Medical

2008
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:10

    Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated; Glutathione; Hepatitis; Homeostasis; Lipid Metabolism; Liver; Methionine; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; S-Adenosylmethionine

2008
Ocular findings among patients with late-diagnosed or poorly controlled homocystinuria compared with a screened, well-controlled population.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2001, Volume: 5, Issue:5

    Topics: Adult; Aging; Astigmatism; Child; Child, Preschool; Cystine; Disease Progression; Female; Homocystine; Homocystinuria; Humans; Infant; Lens Subluxation; Male; Methionine; Myopia; Time Factors; Visual Acuity; Vitamin B 6

2001
L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine.
    Biochemical and biophysical research communications, 2002, Apr-12, Volume: 292, Issue:4

    Topics: Animals; Bacteroidaceae Infections; Carbon-Sulfur Lyases; Disease Progression; Drug Evaluation, Preclinical; Female; Halitosis; Methionine; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Porphyromonas gingivalis; Sulfhydryl Compounds; Survival Rate; Virulence

2002
Potential significance of (11)C-methionine PET as a marker for the radiosensitivity of low-grade gliomas.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:5

    Topics: Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Disease Progression; Disease-Free Survival; Dose Fractionation, Radiation; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methionine; Middle Aged; Radiopharmaceuticals; Retrospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed; Treatment Outcome

2002