methionine has been researched along with Colonic Neoplasms in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (12.82) | 18.7374 |
| 1990's | 26 (33.33) | 18.2507 |
| 2000's | 25 (32.05) | 29.6817 |
| 2010's | 11 (14.10) | 24.3611 |
| 2020's | 6 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, HJ; Kim, J; Lee, J; Oh, JH; Shin, A; Sohn, DK | 1 |
| Burgos-Morón, E; Calderón-Montaño, JM; Díaz-Ortega, P; Guillén-Mancina, E; Jiménez-Alonso, JJ; Jiménez-González, V; López-Lázaro, M | 1 |
| Fang, H; He, H; Li, Y; Liu, Y; Qing, L; Wang, Z; Zhang, S; Zhang, Y | 1 |
| Bouvet, M; Endo, I; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Kumamoto, T; Matsuyama, R; Miyake, K; Nishino, H; Sugisawa, N; Yamamoto, J | 1 |
| Abbruzzese, JL; Bi, Y; Hu, L; Huang, H; Ji, J; Kim, E; Li, X; Li, Z; Liu, M; Lu, W; Luo, CK; Luo, Y; Ma, J; Wang, D; Wang, G; Yang, VW; Zhu, L | 1 |
| Arsenijević, A; Arsenijević, N; Ćoćić, D; Lazić, D; Milovanović, J; Milovanović, M; Rilak Simović, A; Scheurer, A; Stojanović, B | 1 |
| Chawla, AT; Cororaton, AD; Ellis, KC; Grossman, SR; Koblinski, JE; Korwar, S; Kovi, RC; Love, IM; Sumner, ET; Szomju, BB | 1 |
| Du, YF; Huang, J; Huang, WQ; Luo, WP; Mo, XF; Xu, M; Yan, B; Zhang, CX | 1 |
| Boone, C; Di Giandomenico, D; Lucisano, G; Mosca, MG; Parsons, AB; Porcu, G; Ragnini-Wilson, A | 1 |
| Bu, P; Chen, KY; Lin, CS; Liu, X; Locasale, JW; Rakhilin, N; Shen, X | 1 |
| Fuchs, CS; Ogino, S; Schernhammer, ES | 1 |
| Austin, RC; Campan, M; Chiang, EP; Cho, RC; Choi, SW; Dickhout, J; Jang, H; Kim, YI; Laird, PW; Lucock, M; Sohn, KJ; Wang, YC; Weisenberger, DJ; Yates, Z | 1 |
| Cervinka, M; Hasková, P; Králová, V; Rudolf, E; Schröterová, L; Vorácová, A | 1 |
| Chinnadurai, G; Zhao, LZ | 1 |
| Grossman, SR; Kovi, RC; Lyle, S; Paliwal, S; Parker, D; Rajeshkumar, B; Schiffer, CA; Straza, MW; Trenh, P; Whalen, GF | 1 |
| Baba, Y; Fuchs, CS; Giovannucci, E; Ogino, S; Schernhammer, ES | 1 |
| Akita, K; Aoki, S; Chiba, Y; Fuji, M; Hosoya, N; Ishii, Y; Ishikawa, H; Kawai, K; Nakajima, M; Ohsaka, T; Okajima, T; Onuma, K; Saeki, Y; Sato, T; Senawongse, P; Shoun, H; Sugawara, Y; Sugiyama, S; Suzuki, T; Takahashi, M; Tsuboi, M; Urushiyama, A; Yagi, S; Yamagishi, K; Yamanaka, T | 1 |
| El-Sayed, AS; Nassrat, HM; Shouman, SA | 1 |
| Caan, BJ; Curtin, K; Liu, AY; Makar, K; Poole, E; Potter, JD; Scherer, D; Slattery, ML; Ulrich, CM | 1 |
| Aghasadeghi, MR; Alavidjeh, MS; Amanlou, M; Ardestani, MS; Daha, FJ; Ebrahimi, SE; Ghorbani, M; Khosroshahi, AG; Mousavi, L; Pouriayevali, MH; Sabzevari, O; Sadat, SM | 1 |
| Franceschi, S; La Vecchia, C; Negri, E; Pelucchi, C | 1 |
| Inoue, M; Kusama, T; Matsumoto, Y; Mukai, M; Nakamura, H; Tatsuta, M | 1 |
| Alink, GM; Geerse, GJ; Klaassens, ES; van Boekel, MA; Vis, EH | 1 |
| Chen, K; Jiang, Q; Li, Q; Ma, X; Shu, G; Yao, K; Yu, W | 1 |
| Aydin, F; Kavgaci, H; Ovali, E; Ozdemir, F; Yavuz, A; Yavuz, M | 1 |
| Chen, K; Chen, Q; Fan, CH; Jin, MJ; Ma, XY; Song, L; Yao, KY; Zhu, YM | 1 |
| Barrett, DA; Fouladi-Nashta, AA; Halliday, N; Li, D; Sinclair, KD; Singh, R | 1 |
| Herz, M; Schwaiger, M; Seidl, C; Senekowitsch-Schmidtke, R; Stöber, B; Tanase, U | 1 |
| Komninou, D; Leutzinger, Y; Reddy, BS; Richie, JP | 1 |
| Ferrer, R; Geraert, PA; Martín-Venegas, R; Rodríguez-Lagunas, MJ | 1 |
| Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R | 1 |
| Baykus, H; Dommels, Y; Kampman, E; Keijer, J; Kok, F; Lips, E; Pellis, L; Polanen, Av; Venema, D | 1 |
| Lipkin, M; Mikol, YB | 1 |
| Abeles, RH; Dexter, DL; Ghoda, LY; Parks, RE; Savarese, TM; Trackman, PC | 1 |
| Hauri, HP; Naim, H; Sander, B | 1 |
| Molmenti, EP; Perlmutter, DH; Ziambaras, T | 1 |
| Hauri, HP; Linstedt, AD | 1 |
| Ascherio, A; Colditz, GA; Giovannucci, E; Rimm, EB; Stampfer, MJ; Willett, WC | 1 |
| Jou, TS; Marrs, JA; Nelson, WJ; Stappert, J; Stewart, DB | 1 |
| Nichols, BL; Paul, EC; Quaroni, A | 1 |
| Born, E; Chen, H; Dixon, B; Field, FJ; Mathur, S | 1 |
| Le Pendu, J; Meflah, K; Ménoret, A | 1 |
| Berger, MR; Haberkorn, U; Morr, I; Oberdorfer, F; Schaider, H; van Kaick, G | 1 |
| Edwards, SL; Ma, KN; Potter, JD; Schaffer, D; Slattery, ML | 1 |
| Colditz, GA; Fuchs, C; Giovannucci, E; Hunter, DJ; Rosner, BA; Speizer, FE; Stampfer, MJ; Willett, WC | 1 |
| Heiss, P; Mattes, J; Matzen, K; Schwaiger, M; Senekowitsch-Schmidtke, R; Truckenbrodt, R | 1 |
| Mallon, RG; Paty, PB; Picon, A; Wojciechowicz, DC | 1 |
| Leppert, M; Potter, JD; Samowitz, W; Schaffer, D; Slattery, ML | 1 |
| An, Z; Han, Q; Hoffman, RM; Rashidi, B; Sasson, A; Sun, FX; Sun, X; Tan, X; Tan, Y; Wang, X; Xu, M | 1 |
| Kubota, T | 1 |
| Cherian, SP; Gu, WZ; Leal, JA; Ng, SC; O'Connor, S; Rosenberg, SH; Tahir, SK; Wang, YC; Zhang, HC | 1 |
| Dutrillaux, B; Gonçalves, RA; Miccoli, L; Poirson-Bichat, F; Poupon, MF | 1 |
| Dale, TC; Davis, E; Rozycka, M; Sara, E; Smalley, M; Webster, MT; Wooster, R; Young, N | 1 |
| Brand, GM; Duthie, SJ; Grant, G; Narayanan, S | 1 |
| Bernhard, EJ; Cerniglia, G; Cohen-Jonathan, E; Evans, SM; Gibbs, JB; Gillies McKenna, W; Hamilton, AD; Kohl, N; Kusewitt, D; Mick, R; Muschel, RJ; Oliff, A; Sebti, SM | 1 |
| Arab, L; Su, LJ | 1 |
| Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K | 1 |
| Gaben, AM; Mester, J; Redeuilh, G; Villerbu, N | 1 |
| Colditz, GA; Fuchs, CS; Giovannucci, EL; Hunter, DJ; Speizer, FE; Stampfer, MJ; Willett, WC | 1 |
| Fischman, J | 1 |
| Pereira, P; Rozen, R; Sabbaghian, N; Schievella, AR; Sekhon, J | 1 |
| Davis, WG; Delaney, PV; Tormey, WP | 1 |
| Boll, D; Dickman, S; Kushner, JP; Quagliana, J | 1 |
| Kaibara, N; Maeta, M; Sugihara, K | 1 |
| Erickson, RH; Gum, E; Kim, YS; Matsumoto, H; Yoshioka, M | 1 |
| Baricault, L; Girr, M; Guéant, JL; Nexø, E; Nicolas, JP; Schohn, H; Zweibaum, A | 1 |
| Ramanujam, KS; Ramasamy, M; Seetharam, B; Seetharam, S | 1 |
| Bagshawe, KD; Bradshaw, T; Mellor, B; Melton, RG; Pedley, RB; Searle, F; Sherwood, RF | 1 |
| Bucher, K; Hauri, HP; Matter, K | 1 |
| Antoine, E; Breillout, F; Poupon, MF | 1 |
| Brauchbar, M; Bucher, K; Hauri, HP; Matter, K | 1 |
| Erickson, RH; Gum, E; Gum, JR; Kim, YS; Matsumoto, H; Yoshioka, M | 1 |
| el Battari, A; Fantini, J; Giannellini, F; Luis, J; Martin, JM; Marvaldi, J; Pichon, J | 1 |
| Brattain, MG; Chakrabarty, S; Tobon, A; Varani, J | 1 |
| Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK | 1 |
| Byrd, JC; Gum, JR; Hicks, JW; Kam, WK; Kim, YS; Sleisenger, MH | 1 |
| Albano, WA; Biscone, KA; Deschner, EE; Kimberling, WJ; Lipkin, ML; Lynch, HT; Lynch, JF; Mikol, YB; Sandberg, AA; Schuelke, GS | 1 |
| Ben-Porath, M; Kaplan, E | 1 |
1 review(s) available for methionine and Colonic Neoplasms
| Article | Year |
|---|---|
[Theoretical basis for low-dose CDDP/5-FU therapy].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Stomach Neoplasms | 1999 |
2 trial(s) available for methionine and Colonic Neoplasms
| Article | Year |
|---|---|
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine | 2007 |
[Methionine-deprived amino acid solution-induced biochemical modulation of 5-FU and augmentation of the antitumor activity].
Topics: Amino Acids; Colonic Neoplasms; Fluorouracil; Humans; Methionine; Parenteral Nutrition, Total; Retinol-Binding Proteins; Stomach Neoplasms; Thymidylate Synthase | 1992 |
75 other study(ies) available for methionine and Colonic Neoplasms
| Article | Year |
|---|---|
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status.
Topics: Case-Control Studies; Choline; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA Mismatch Repair; Folic Acid; Humans; Methionine; Microsatellite Instability; Niacin; Nutrients; Polymorphism, Genetic; Risk Factors | 2022 |
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma.
Topics: Amino Acids, Sulfur; Animals; Carcinoma, Renal Cell; Caseins; Colonic Neoplasms; Cysteine; Diet; Female; Humans; Kidney Neoplasms; Leucine; Lipids; Methionine; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Racemethionine; Taurine | 2023 |
Design and Structural Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High In Vivo Potency and Oral Bioavailability.
Topics: Animals; Biological Availability; Colonic Neoplasms; Humans; Methionine; Methionine Adenosyltransferase; Mice | 2023 |
Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells.
Topics: Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Fibroblasts; Histones; Humans; Lung Neoplasms; Methionine; Methylation; Recombinant Proteins | 2020 |
Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Death; Colonic Neoplasms; Enzyme Inhibitors; Female; Genes, p53; Genes, ras; Glutamate-Cysteine Ligase; Glutathione; HCT116 Cells; Humans; Methionine; Mice, Nude; Mice, Transgenic; Mutation; NADPH Oxidases; Onium Compounds; Ovarian Neoplasms; Oxidative Stress; Pancreatic Neoplasms; Signal Transduction; Sulfoxides; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
A new bis-pyrazolylpyridine ruthenium(III) complex as a potential anticancer drug:
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Coordination Complexes; DNA; Guanosine Monophosphate; Histidine; Male; Methionine; Mice, Inbred BALB C; Molecular Docking Simulation; Pyrazoles; Pyridines; Ruthenium; Serum Albumin, Human; Tumor Burden | 2021 |
Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Alcohol Oxidoreductases; Animals; beta Catenin; Carcinogenesis; Cell Line, Tumor; Co-Repressor Proteins; Colonic Neoplasms; Cyclin D; DNA-Binding Proteins; Fibroblasts; Humans; Methionine; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Phosphoproteins | 2017 |
[Effect of peripheral bloodgenomic DNA methylation on the relationship between methyl donor status and risk of breast cancer].
Topics: Betaine; Breast Neoplasms; Case-Control Studies; Choline; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Risk | 2017 |
Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Farnesyltranstransferase; Female; Humans; Lung Neoplasms; Melanoma; Methionine; p21-Activated Kinases | 2013 |
A metabolic signature of colon cancer initiating cells.
Topics: AC133 Antigen; Antigens, CD; Biomarkers, Tumor; Carbohydrate Metabolism; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Down-Regulation; Gene Frequency; Glycolysis; Glycoproteins; Humans; Mass Spectrometry; Metabolome; Methionine; Neoplastic Stem Cells; Peptides; Transcriptome | 2014 |
Folate and vitamin B6 intake and risk of colon cancer in relation to p53 expression.
Topics: Alcohol Drinking; Colonic Neoplasms; Diet; Female; Folic Acid; Folic Acid Deficiency; Genes, p53; Humans; Immunohistochemistry; Methionine; Middle Aged; Oligonucleotide Array Sequence Analysis; Risk Factors; Tumor Suppressor Protein p53; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2008 |
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification.
Topics: Blotting, Western; Breast Neoplasms; Colonic Neoplasms; CpG Islands; DNA Damage; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Tumor Cells, Cultured; Uracil | 2009 |
Antiproliferative effects of selenium compounds in colon cancer cells: comparison of different cytotoxicity assays.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cysteine; Cytotoxins; Humans; Methionine; Organoselenium Compounds; Selenocysteine; Sodium Selenite; Toxicity Tests | 2009 |
Incapacitating CtBP to kill cancer.
Topics: Alcohol Oxidoreductases; Apoptosis; Apoptosis Regulatory Proteins; Colonic Neoplasms; DNA-Binding Proteins; Histone Deacetylases; Histone Demethylases; Humans; Intercalating Agents; Membrane Proteins; Methionine; Mitochondrial Proteins; RNA Interference | 2010 |
Therapeutic targeting of C-terminal binding protein in human cancer.
Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Chromatin Immunoprecipitation; Colonic Neoplasms; DNA-Binding Proteins; HCT116 Cells; Humans; Membrane Proteins; Methionine; Mice; Mice, Nude; Mitochondrial Proteins; Repressor Proteins; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2010 |
B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Topics: Adaptor Proteins, Signal Transducing; Adult; Basic Helix-Loop-Helix Transcription Factors; Calcium Channels, T-Type; Cell Cycle Proteins; Colonic Neoplasms; Core Binding Factor Alpha 3 Subunit; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Female; Folic Acid; Humans; Insulin-Like Growth Factor II; Kruppel-Like Transcription Factors; Methionine; Middle Aged; Mutation; MutL Protein Homolog 1; Neoplasm Proteins; Nerve Tissue Proteins; Nuclear Proteins; Poly-ADP-Ribose Binding Proteins; Polymerase Chain Reaction; Proto-Oncogene Proteins B-raf; Receptors, Retinoic Acid; Risk Factors; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Surveys and Questionnaires; Ubiquitin-Protein Ligases | 2011 |
Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment.
Topics: Animals; Antineoplastic Agents; Breath Tests; Cell Proliferation; Chromatography, Gas; Colonic Neoplasms; Diffusion; Drug Evaluation, Preclinical; Female; Flatulence; Gases; Glucose; Humans; Hyaluronic Acid; Hydrogen Sulfide; Lung Neoplasms; Maillard Reaction; Methionine; Mice; Mice, Nude; Neoplasm Transplantation; Sulfhydryl Compounds; Sulfur Compounds; Transplantation, Heterologous; X-Ray Absorption Spectroscopy | 2012 |
Pharmacokinetics, immunogenicity and anticancer efficiency of Aspergillus flavipes L-methioninase.
Topics: Animals; Antineoplastic Agents; Aspergillus; Carbon-Sulfur Lyases; Cell Line, Tumor; Colonic Neoplasms; Half-Life; Humans; Lung Neoplasms; Male; MCF-7 Cells; Methionine; Prostatic Neoplasms; Rabbits | 2012 |
Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.
Topics: Adult; Aged; Case-Control Studies; Colonic Neoplasms; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine Hydroxymethyltransferase; Humans; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Genetic; Riboflavin; Risk Factors; Vitamin B 12; Vitamin B 6 | 2013 |
A comparative study of two novel nanosized radiolabeled analogues of methionine for SPECT tumor imaging.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Colon; Colonic Neoplasms; Dendrimers; Humans; Methionine; Mice; Mice, Inbred BALB C; Neoplasms; Organotechnetium Compounds; Pentetic Acid; Tomography, Emission-Computed, Single-Photon | 2013 |
Dietary folate and colorectal cancer.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Rectal Neoplasms | 2002 |
Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
Topics: Alkyl and Aryl Transferases; Benzamides; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Humans; Methionine; Mevalonic Acid; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Prenylation; Signal Transduction; Tumor Cells, Cultured | 2003 |
Possible mechanisms behind the differential effects of soy protein and casein feedings on colon cancer biomarkers in the rat.
Topics: Alkaline Phosphatase; Animals; Bile Acids and Salts; Biomarkers; Caseins; Cell Division; Colonic Neoplasms; Dietary Proteins; Feces; Lipids; Magnesium; Male; Methionine; Random Allocation; Rats; Rats, Wistar; Saponins; Soybean Proteins | 2005 |
Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer.
Topics: Aged; Alcohol Drinking; Case-Control Studies; Colonic Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Rectal Neoplasms | 2005 |
Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Combined Modality Therapy; Farnesyltranstransferase; Fluorouracil; Humans; Methionine; Radiation Tolerance | 2005 |
The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.
Topics: Adult; Aged; Amino Acid Substitution; Base Sequence; China; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; DNA Primers; DNA Repair; DNA-Binding Proteins; Female; Genotype; Humans; Male; Methionine; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Rectal Neoplasms; Registries; Risk Factors; Threonine | 2005 |
Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation.
Topics: Adenocarcinoma; Adenosine; Alkaline Phosphatase; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Cyclic AMP; Extracellular Signal-Regulated MAP Kinases; HT29 Cells; Humans; Hypoxanthines; MAP Kinase Kinase Kinases; Methionine; Methotrexate; Phosphatidylinositol 3-Kinases; Polyamines; Purines; Signal Transduction; Tetrahydrofolates; Thymidine | 2006 |
Differentiation of tumour and inflammation: characterisation of [methyl-3H]methionine (MET) and O-(2-[18F]fluoroethyl)-L-tyrosine (FET) uptake in human tumour and inflammatory cells.
Topics: Cells, Cultured; Colonic Neoplasms; Diagnosis, Differential; Fluorine Radioisotopes; Humans; Inflammation; Metabolic Clearance Rate; Methionine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2006 |
Methionine restriction inhibits colon carcinogenesis.
Topics: Animals; Azoxymethane; Biological Assay; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Methionine; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2006 |
Monocarboxylate transporter 1 mediates DL-2-Hydroxy-(4-methylthio)butanoic acid transport across the apical membrane of Caco-2 cell monolayers.
Topics: Biological Transport; Cell Line, Tumor; Cell Membrane; Colonic Neoplasms; Humans; Kinetics; Methionine; Monocarboxylic Acid Transporters; Symporters | 2007 |
High folic acid increases cell turnover and lowers differentiation and iron content in human HT29 colon cancer cells.
Topics: Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Dietary Supplements; Epithelial Cells; Folic Acid; Gene Expression Profiling; HT29 Cells; Humans; Iron; Methionine; Oligonucleotide Array Sequence Analysis; Tetrahydrofolates; Vitamin B 12; Vitamin B Complex | 2008 |
Methionine dependence in skin fibroblasts of humans affected with familial colon cancer or Gardner's syndrome.
Topics: Adolescent; Adult; Aged; Cell Line; Colonic Neoplasms; Culture Media; Female; Fibroblasts; Gardner Syndrome; Humans; In Vitro Techniques; Male; Methionine; Middle Aged; Phenotype; Skin | 1984 |
Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma.
Topics: Adenosine; Animals; Cell Line; Colonic Neoplasms; Deoxyadenosines; Humans; Liver; Methionine; Rats; Ribosemonophosphates; Ribulosephosphates; Thioglycosides; Thionucleosides | 1984 |
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; beta-Galactosidase; Bucladesine; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epithelium; Humans; Lactase; Lactase-Phlorizin Hydrolase; Methionine; Microvilli; Sucrase-Isomaltase Complex; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Evidence for an acute phase response in human intestinal epithelial cells.
Topics: Acute-Phase Proteins; Adenocarcinoma; alpha 1-Antichymotrypsin; alpha 1-Antitrypsin; Cell Differentiation; Cell Line; Cell Membrane; Colonic Neoplasms; Complement Factor B; Cytokines; Epidermal Growth Factor; Epithelium; Humans; Interferon-gamma; Interleukin-1; Interleukin-6; Intestinal Mucosa; Kinetics; Methionine; Recombinant Proteins; Sulfur Radioisotopes; Transferrin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Biological Evolution; Cell Line; Colonic Neoplasms; Conserved Sequence; Cytoplasm; Epitopes; Fluorescent Antibody Technique; Galactosyltransferases; Glycosylation; Golgi Apparatus; Humans; Membrane Proteins; Methionine; Molecular Weight; Tumor Cells, Cultured | 1993 |
Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men.
Topics: Adenoma; Adult; Aged; Alcohol Drinking; Carcinoma; Colonic Neoplasms; Diet; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk Factors; Surveys and Questionnaires | 1995 |
Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex.
Topics: Adenocarcinoma; alpha Catenin; Amino Acid Sequence; Animals; Base Sequence; beta Catenin; Binding Sites; Cadherins; Cell Line; Cloning, Molecular; Colonic Neoplasms; Cytoskeletal Proteins; DNA Primers; Dogs; Humans; Methionine; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Saccharomyces cerevisiae; Trans-Activators; Tumor Cells, Cultured | 1995 |
Intracellular degradation and reduced cell-surface expression of sucrase-isomaltase in heat-shocked Caco-2 cells.
Topics: Adenocarcinoma; Aminopeptidases; Antibodies, Monoclonal; CD13 Antigens; Cell Membrane; Colonic Neoplasms; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Fluorescent Antibody Technique; Hot Temperature; Humans; Kinetics; Lysosomes; Methionine; Microvilli; Protein Processing, Post-Translational; Sucrase-Isomaltase Complex; Sulfur Radioisotopes; Time Factors; Tumor Cells, Cultured | 1993 |
Release of ceramide after membrane sphingomyelin hydrolysis decreases the basolateral secretion of triacylglycerol and apolipoprotein B in cultured human intestinal cells.
Topics: Apolipoproteins B; Cell Membrane; Cell Survival; Ceramides; Cholesterol Esters; Colonic Neoplasms; Humans; Hydrolysis; Intestinal Mucosa; Kinetics; Lipids; Methionine; Phospholipids; Protein Kinase C; RNA, Messenger; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Triglycerides; Tumor Cells, Cultured; Type C Phospholipases | 1993 |
Expression of the 100-kda glucose-regulated protein (GRP100/endoplasmin) is associated with tumorigenicity in a model of rat colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Blotting, Western; Carrier Proteins; Cell Survival; Colonic Neoplasms; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Chaperone BiP; Glucose; Glycosylation; Heat-Shock Proteins; Kinetics; Membrane Glycoproteins; Membrane Proteins; Methionine; Molecular Chaperones; Rats; Time Factors; Tumor Cells, Cultured; Tunicamycin | 1994 |
Application of alpha-aminoisobutyric acid, L-methionine, thymidine and 2-fluoro-2-deoxy-D-glucose to monitor effects of chemotherapy in a human colon carcinoma cell line.
Topics: Aminoisobutyric Acids; Antineoplastic Agents; Carbon Radioisotopes; Colonic Neoplasms; Deoxyglucose; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fluorodeoxyglucose F18; Humans; In Vitro Techniques; Methionine; Phenylenediamines; Thymidine; Tomography, Emission-Computed; Tritium; Tumor Cells, Cultured | 1996 |
Are dietary factors involved in DNA methylation associated with colon cancer?
Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Pyridoxine; Retrospective Studies; Risk Factors; Vitamin B 12 | 1997 |
Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study.
Topics: Adult; Colonic Neoplasms; Confounding Factors, Epidemiologic; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Incidence; Methionine; Middle Aged; Multivariate Analysis; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors; Vitamins | 1998 |
Tumor cell spheroids as a model for evaluation of metabolic changes after irradiation.
Topics: Adenocarcinoma; Carbon Radioisotopes; Colonic Neoplasms; Deoxyglucose; Humans; In Vitro Techniques; Methionine; Radiopharmaceuticals; Spheroids, Cellular; Thymidine; Tritium; Tumor Cells, Cultured | 1998 |
Characterization of lectin resistant cell populations derived from human colon carcinoma: correlation of K-Ras with beta1-6 branching of N-linked carbohydrate and CEA production.
Topics: Carcinoembryonic Antigen; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lectins; Methionine; Phytohemagglutinins; Precipitin Tests; ras Proteins; Tumor Cells, Cultured | 1999 |
Methylenetetrahydrofolate reductase, diet, and risk of colon cancer.
Topics: Adult; Aged; Alcohol Drinking; California; Case-Control Studies; Colonic Neoplasms; Diet; Diet Surveys; DNA Methylation; Female; Folic Acid; Genotype; Homozygote; Humans; Incidence; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Vitamin B 12 | 1999 |
Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carbon-Sulfur Lyases; Cell Division; Cisplatin; Colonic Neoplasms; Female; Humans; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Recombinant Proteins; Time Factors; Tumor Cells, Cultured | 1999 |
Effect of novel CAAX peptidomimetic farnesyltransferase inhibitor on angiogenesis in vitro and in vivo.
Topics: Alkyl and Aryl Transferases; Animals; Colonic Neoplasms; Endothelial Growth Factors; Endothelium, Vascular; Farnesyltranstransferase; Humans; Lymphokines; Methionine; Mice; Mice, Nude; Neovascularization, Pathologic; Pyridines; Rats; Tumor Cells, Cultured; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Brain Neoplasms; Carcinoma, Small Cell; Cell Division; Colonic Neoplasms; Dietary Supplements; Drug Resistance, Multiple; Ethionine; Female; Genes, MDR; Glioma; Glutathione; Homocysteine; Humans; Lung Neoplasms; Male; Methionine; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasms; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding.
Topics: Amino Acid Sequence; Amino Acid Substitution; Axin Protein; Base Sequence; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Colonic Neoplasms; Female; Genetic Variation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Leucine; Male; Methionine; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Ovarian Neoplasms; Protein Binding; Proteins; Repressor Proteins; Tumor Cells, Cultured | 2000 |
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats.
Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS.
Topics: Alkyl and Aryl Transferases; Animals; Colonic Neoplasms; Enzyme Inhibitors; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methionine; Mice; Mice, Nude; Neoplasm Recurrence, Local; Neoplasm Transplantation; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 2000 |
Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study.
Topics: Adult; Aged; Alcohol Drinking; Colonic Neoplasms; Diet; Female; Folic Acid; Health Surveys; Humans; Male; Methionine; Middle Aged; Nutritional Status; Risk Factors; Smoking; United States | 2001 |
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12 | 2001 |
Cellular effects of purvalanol A: a specific inhibitor of cyclin-dependent kinase activities.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Female; HeLa Cells; HT29 Cells; Humans; Methionine; Microfilament Proteins; Muscle Proteins; Phosphorylation; Retinoblastoma Protein; Transcription, Genetic; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2002 |
The influence of folate and multivitamin use on the familial risk of colon cancer in women.
Topics: Adult; Alcoholic Beverages; Cohort Studies; Colonic Neoplasms; Feeding Behavior; Female; Folic Acid; Health Behavior; Humans; Methionine; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; United States; Vitamins | 2002 |
Cancer and diet. Colon vitamins.
Topics: Alcohol Drinking; Colonic Neoplasms; Diet; DNA Damage; DNA Repair; Female; Folic Acid; Humans; Methionine; United States | 2002 |
Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Colonic Neoplasms; Enzyme Inhibitors; Exons; Female; Fibroblasts; Genetic Therapy; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Neuroblastoma; Oligodeoxyribonucleotides, Antisense; Oxidoreductases Acting on CH-NH Group Donors; RNA, Messenger; RNA, Neoplasm; Thionucleotides; Tumor Cells, Cultured; Vitamin B 12 | 2002 |
Enkephalins in large bowel malignancy and in acute appendicitis.
Topics: Acute Disease; Adenocarcinoma; Appendicitis; Appendix; Cecal Neoplasms; Colon; Colonic Neoplasms; Endorphins; Enkephalins; Humans; Leucine; Methionine | 1979 |
Elevated methionine-tRNA synthetase activity in human colon cancer.
Topics: Adenocarcinoma; Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Colonic Neoplasms; Humans; Intestinal Mucosa; Methionine; Methionine-tRNA Ligase | 1976 |
Expression of dipeptidyl aminopeptidase IV during enterocytic differentiation of human colon cancer (Caco-2) cells.
Topics: Cell Differentiation; Cell Line; Cell Membrane; Colonic Neoplasms; Cytosol; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Induction; Fluorescent Antibody Technique; Humans; Kinetics; Methionine | 1991 |
Synthesis and secretion of a cobalamin-binding protein by HT 29 cell line.
Topics: Blotting, Western; Chromatography, Affinity; Colonic Neoplasms; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Humans; Methionine; Transcobalamins; Tumor Cells, Cultured; Vitamin B 12 | 1991 |
Expression of cobalamin transport proteins and cobalamin transcytosis by colon adenocarcinoma cells.
Topics: Adenocarcinoma; Biological Transport; Cell Line; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Humans; Intrinsic Factor; Kinetics; Methionine; Molecular Weight; Sulfur Radioisotopes; Transcobalamins; Vitamin B 12 | 1991 |
Carboxypeptidase G2 and trimetrexate cause growth delay of human colonic cancer cells in vitro.
Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Cell Division; Colonic Neoplasms; Culture Media; Homocysteine; Humans; Methionine; Mice; Quinazolines; Rabbits; Trimetrexate; Tumor Cells, Cultured | 1990 |
Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2).
Topics: Adenocarcinoma; Cell Line; Cell Membrane; Colonic Neoplasms; Endocytosis; Epithelium; Humans; Kinetics; Membrane Glycoproteins; Membrane Proteins; Methionine; Microtubules; Nocodazole; Tubulin | 1990 |
Methionine dependency of malignant tumors: a possible approach for therapy.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Movement; Colonic Neoplasms; Culture Media; Female; Homocysteine; Humans; Lung Neoplasms; Methionine; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Tumor Cells, Cultured | 1990 |
Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2).
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antigens, Surface; Cell Line; Cell Membrane; Colonic Neoplasms; Epithelium; Humans; Kinetics; Membrane Proteins; Methionine; Models, Biological; Protein Processing, Post-Translational; Tumor Cells, Cultured | 1990 |
Biosynthesis of alkaline phosphatase during differentiation of the human colon cancer cell line Caco-2.
Topics: Alkaline Phosphatase; Biomarkers, Tumor; Cell Line, Transformed; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Humans; Methionine; Microvilli; Molecular Weight; Precipitin Tests; Sulfur Radioisotopes; Tumor Cells, Cultured | 1990 |
Cycloheximide induces accumulation of vasoactive intestinal peptide (VIP) binding sites at the cell surface of a human colonic adenocarcinoma cell line (HT29-D4). Evidence for the presence of an intracellular pool of VIP receptors.
Topics: Adenocarcinoma; Binding Sites; Cell Line; Chymotrypsin; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Humans; Kinetics; Methionine; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide | 1987 |
Induction of carcinoembryonic antigen secretion and modulation of protein secretion/expression and fibronectin/laminin expression in human colon carcinoma cells by transforming growth factor-beta.
Topics: Carcinoembryonic Antigen; Cell Line; Collagen; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Fibronectins; Fluorescent Antibody Technique; Humans; Laminin; Methionine; Molecular Weight; Peptides; Proteins; Transforming Growth Factors | 1988 |
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine | 1986 |
Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase.
Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Colonic Neoplasms; Enzyme Induction; Female; Humans; Isoenzymes; Kinetics; Methionine; Placenta; Pregnancy; RNA, Messenger | 1987 |
Hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). II. Biomarker studies.
Topics: Colon; Colonic Neoplasms; Cytogenetics; Fibroblasts; Genetic Carrier Screening; Genetic Linkage; Genotype; Humans; Immunoglobulins; Methionine; Ploidies; Rectal Neoplasms; Risk; Skin Physiological Phenomena; Thymidine | 1985 |
The distribution and concentration of 75Se-selenomethionine in man.
Topics: Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Humans; Liver Neoplasms; Male; Methionine; Radioisotopes; Selenium | 1969 |