methionine has been researched along with Cell Transformation, Neoplastic in 119 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 66 (55.46) | 18.7374 |
1990's | 30 (25.21) | 18.2507 |
2000's | 12 (10.08) | 29.6817 |
2010's | 9 (7.56) | 24.3611 |
2020's | 2 (1.68) | 2.80 |
Authors | Studies |
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Abe, A; Miyajima, K; Nakae, D; Nakane, S; Suzuki-Kemuriyama, N; Yuki, M | 1 |
Barve, A; Beverly, LJ; Casson, L; Ghare, S; Shah, PP; Siskind, LJ; Vega, A; Wunderlich, M | 1 |
Aoki, Y; Bouvet, M; Endo, I; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Matsuyama, R; Miyake, K; Nishino, H; Sugisawa, N; Sun, YU; Yamamoto, J | 1 |
Ewing, LE; Griffin, RJ; Koturbash, I; Kutanzi, KR; Miousse, IR | 1 |
Che, R; Fei, P; Jia, W; Panneerselvam, J; Su, M; Xie, G; Zhang, J | 1 |
Empl, MT; Gerhard, D; Hausmann, J; Nicken, P; Steinberg, P | 1 |
Guo, X; Huang, C; Huang, H; Jin, H; Li, J; Peng, M; Tang, MS; Tian, Z; Wu, XR; Xu, J; Zhu, J | 1 |
Buechler, C; Eisinger, K; Haberl, EM; Krautbauer, S; Neumann, M; Pohl, R; Rein-Fischboeck, L; Weiss, TS; Zimny, S | 1 |
Fang, D; Gan, H; Wang, H; Zhang, Z; Zhou, H | 1 |
Horiuchi, M; Izumo, K; Kawai, Y; Kawano, Y; Miyahara, E; Nishikawa, T; Okamoto, Y; Takeuchi, T | 1 |
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA | 1 |
Chintapalli, J; Du, W; Prendergast, GC; Rane, N; Zeng, PY | 1 |
Baker, J; Donover, S; Du, W; DuHadaway, JB; Liu, AX; Muller, AJ; Prendergast, GC; Sharp, DM | 1 |
Barnard, J; Coffey, RJ; Du, J; Jiang, B | 1 |
Dai, Y; Dent, P; Grant, S; Han, SI; Khanna, P; Mitchell, C; Pei, XY; Rahmani, M | 1 |
Limnander, A; Niki, M; Oki, S; Pandolfi, PP; Rothman, PB; Yao, PM | 1 |
Bosch, X; Castellsagué, X; García-Closas, R; González, CA | 1 |
Ataullakhanov, FI; Banerjee, R; Martinov, MV; Prudova, A; Vitvitsky, VM | 1 |
Lim, U; Ziegler, RG | 1 |
Khosravi, MJ; Kobrin, MS; Kudlow, JE; Mak, WW | 1 |
Hoffman, RM | 2 |
August, JT; Skubitz, KM; Zhen, YS | 1 |
Carson, K; Clarke, S; Hoffman, RM; Mecham, JO; Oden, KL | 1 |
Heby, O; Kanje, M; Oredsson, SM | 1 |
Kishimoto, S; Matsumoto, K; Nakao, M; Nishizawa, Y; Noma, K; Sato, B | 1 |
Koziorowska, J; Paczek, K; Tautt, J | 1 |
Myasishcheva, NV; Poirier, LA; Stoner, GD; Wilson, MJ | 1 |
Kakunaga, T; Leavitt, J | 1 |
Poirier, LA; Wilson, MJ | 2 |
Anuszewska, EL; Koziorowska, JH; Tautt, JW | 1 |
Rothenberg, E | 1 |
Booyens, J; Dippenaar, N; Fabbri, D; Katzeff, IE | 1 |
Tautt, J | 1 |
Tisdale, MJ | 1 |
Bravo, R; Celis, JE; Fey, SJ | 1 |
Blaskovich, MA; Cox, AD; Der, CJ; Fossum, RD; Hamilton, AD; Lerner, EC; Qian, Y; Sebti, SM; Sun, J; Vogt, A | 1 |
Branton, PE; Corbeil, HB | 1 |
Chen, ZP; Leavitt, J; Park, T | 1 |
Akiyama, T; Aoki, M; Hamada, F; Sugimoto, T; Sumida, S; Toyoshima, K | 1 |
Gotoh, B; Hamaguchi, M; Matsuyoshi, N; Nagai, Y; Ohnishi, Y; Takeichi, M | 1 |
Kaufman, DG; Laundon, CH; Lyn-Cook, BD; Mayben, JP; Rinehart, CA | 1 |
Gatton-Umphress, TL; Seidler, NW; Weber, KA | 1 |
Buss, JE; Cox, AD; Der, CJ; Graham, SM; Solski, PA | 1 |
Andahazy, ML; Barbacid, M; Bhide, RS; Carboni, JM; Cho, YH; Gullo-Brown, JL; Hunt, JT; Kline, T; Lee, FY; Leftheris, K; Manne, V; Meyers, CA; Patel, DV; Patel, MM; Ricca, C; Rose, WC; Schmidt, RJ; Seizinger, BR; Vite, GD; Weller, HN; Yan, N; Zahler, R | 1 |
Bernhard, EJ; Cox, AD; Hamilton, AD; Kao, G; McKenna, WG; Muschel, RJ; Sebti, SM | 1 |
Hamilton, AD; McGuire, TF; Qian, Y; Sebti, SM; Vogt, A | 1 |
Bowden, GT; Joseloff, E | 1 |
Carlomagno, F; Cirafici, AM; Dathan, NA; De Vita, G; Fusco, A; Melillo, RM; Salvatore, G; Santoro, M; Visconti, R | 1 |
Aklilu, F; Goltzman, D; Park, M; Rabbani, SA | 1 |
Coffey, RJ; Cox, AD; Der, CJ; Oldham, SM; Reynolds, ER; Sizemore, NS | 1 |
Andres, DA; Chan, TO; Cox, AD; Grana, TM; Reynolds, ER; Rusyn, EV; Shao, H | 1 |
Adnane, J; Bizouarn, FA; Chen, Z; Hamilton, AD; Munoz-Antonia, T; Ohkanda, J; Sebti, SM | 1 |
Béchet, DM; Ferrara, M; Obled, A; Omura, S; Roux, MP; Tournu, C | 1 |
Garcia, AM; Ishihara, H; Kowalczyk, JJ; Lewis, MD; Nagasu, T; Nakamura, K; Namiki, M; Yamaguchi, A; Yoshimatsu, K | 1 |
Bishop, JM; Cordell-Stewart, B; Deng, CT; Faras, AJ; Goodman, HM; Guntaka, RR; Levinson, WE; Taylor, JM; Varmus, HE | 1 |
Gruenstein, E; Rich, A; Robbins, PW; Wickus, G | 1 |
Culp, LA | 1 |
Isaka, T; Owada, M; Toyoshima, K; Yoshida, M | 1 |
Potter, M; Premkumar, E; Singer, PA; Sklar, MD | 1 |
Lawrence, F; Robert-Gero, M; Vigier, P | 1 |
Erbe, RW; Hoffman, RM | 1 |
Kamely, D; Kerwar, SS; Weissbach, H | 1 |
Browne, MJ; Burdon, RH | 1 |
Jacobsen, SJ; Mangum, JH; North, JA; Rao, NA | 1 |
Lawrence, F; Lederer, E; Legraverend, M; Robert-Géro, M; Vedel, M | 1 |
Kaelin, H; Vaheri, A; Vartio, T | 1 |
Chang, C; Martin, MA; Simmons, DT | 1 |
Koch, G; Nuss, DL; Pong, SS | 1 |
Auersperg, N; Luu-The, V; Pan, J; Rojiani, M; Roskelley, CD | 1 |
Binetruy, B; Grover-Bardwick, A; Heidecker, G; Karin, M; Mercola, D; Rapp, UR; Smeal, T | 1 |
Kozma, LM; Rossomando, AJ; Weber, MJ | 1 |
Senger, D; Torsten, U; Weitzel, HK | 1 |
Chaudhari, P; Higgins, PJ; Ryan, MP | 1 |
Hibner, U; Pennetier, JL; Rabilloud, T; Rougeon, F; Tarroux, P; Vincens, P | 1 |
Hirayama, C; Hirayoshi, K; Nagata, K; Nakai, A; Ohtsuka, K | 1 |
Dalianis, T; Linder, S; Martens, I; Ramqvist, T | 1 |
Feldman, RA; Lowy, DR; Vass, WC | 1 |
Han, JW; Macara, IG; Sadowski, H; Young, DA | 1 |
Bover, L; Cafferata, EG; Larcher, F; Medrano, EE; Molinari, B; Podhajcer, O; Resnicoff, M | 1 |
Butler, WT; Chan, JC; Denhardt, DT; Farach-Carson, MC; Mukherjee, BB; Scanlon, M; Singh, K | 1 |
Papas, TS; Seth, A | 1 |
Erickson, RH; Gum, E; Gum, JR; Kim, YS; Matsumoto, H; Yoshioka, M | 1 |
Andry, CD; Kupchik, HZ; Rogers, AE | 1 |
Banks-Schlegel, SP; Rhim, JS | 1 |
Szpirer, C; Vanhamme, L | 2 |
Hipwell, SE; Liteplo, RG | 1 |
Boerner, P; Racker, E | 1 |
Boss, GR; Erbe, RW; Levitt, LJ | 1 |
Alvord, G; Bizub, D; Blair, D; Skalka, AM | 1 |
Feldman, R; Racker, E; Resnick, RJ; Willard, J | 1 |
Belehradek, J; Brada, Z; Hill, M; Hillova, J; Mariage-Samson, R | 1 |
Castagnola, J; MacLeod, C; Mendelsohn, J; Sunada, H; Taetle, R | 1 |
Farber, E; Ghoshal, AK; Sarma, DS | 1 |
Djurhuus, R; Refsum, H; Svardal, AM; Ueland, PM | 1 |
Feldman, R; Racker, E; Resnick, RJ | 1 |
Perruzzi, CA; Senger, DR | 1 |
Hacker, B; Mandel, LR | 1 |
Black, PH; Kaplan, JC; Wilbert, SM | 1 |
Culp, LA; Kolodny, GM; Rosenthal, LJ | 1 |
Hung, P; Kothari, RM; Taylor, M; Wang, S | 1 |
Robbins, PW; Wickus, GG | 1 |
Newton, AA; Rubery, ED | 1 |
Ruoslahti, E; Suni, J; Vaheri, A | 1 |
Nass, MM | 1 |
Hung, PP; Kothari, RM; Taylor, MW; Wang, S | 2 |
Moyer, SA; Summers, DF | 1 |
Rudland, PS; Seeley, M; Seifert, W | 1 |
Ishitsuka, H; Nakajima, K; Oda, K | 1 |
Critchley, DR | 1 |
Evans, VJ; Gantt, R | 1 |
Goldman, M; Griffin, AC | 1 |
Matsushima, T; Weisburger, JH | 1 |
Kraus, P; Semonský, M; Slavíková, V; Veselá, H | 1 |
Evans, VJ; Gantt, R; Quinn, CE | 1 |
Fink, LM; Fujimura, S; Grunberger, D; Weinstein, IB | 1 |
5 review(s) available for methionine and Cell Transformation, Neoplastic
Article | Year |
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DNA Methylation in Radiation-Induced Carcinogenesis: Experimental Evidence and Clinical Perspectives.
Topics: Animals; Cell Transformation, Neoplastic; DNA Damage; DNA Methylation; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methionine; Molecular Targeted Therapy; Mutation; Neoplasms; Radiation, Ionizing; Repetitive Sequences, Nucleic Acid | 2018 |
The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence.
Topics: Carotenoids; Cell Transformation, Neoplastic; Cysteine; Diet; Female; Folic Acid; Homocysteine; Humans; Methionine; Nutritional Physiological Phenomena; Uterine Cervical Neoplasms; Vitamins | 2005 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40 | 1984 |
Methionine dependence in cancer cells - a review.
Topics: Animals; Carbon-Sulfur Lyases; Cell Division; Cell Line; Cell Transformation, Neoplastic; Homocysteine; Humans; Methionine; Neoplasms; Neoplasms, Experimental | 1982 |
Methionine metabolism: a window on carcinogenesis?
Topics: Cell Transformation, Neoplastic; DNA Damage; DNA Repair; Humans; Methionine; Neoplasms; Oncogene Proteins | 1993 |
114 other study(ies) available for methionine and Cell Transformation, Neoplastic
Article | Year |
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Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fibrosis; Interleukin-8; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2023 |
Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia; Leukemia, Biphenotypic, Acute; Methionine; Methyltransferases; Oncogene Proteins, Fusion; Protein Processing, Post-Translational; S-Adenosylmethionine | 2019 |
Reversion from Methionine Addiction to Methionine Independence Results in Loss of Tumorigenic Potential of Highly-malignant Lung-cancer Cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; Methionine; Mice, Nude; Signal Transduction; Tumor Burden | 2021 |
Distinct Metabolic Signature of Human Bladder Cancer Cells Carrying an Impaired Fanconi Anemia Tumor-Suppressor Signaling Pathway.
Topics: Alternative Splicing; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chromatography, Liquid; Epithelial Cells; Fanconi Anemia Complementation Group L Protein; Gene Expression; Humans; Mass Spectrometry; Metabolome; Methionine; Phenylalanine; Protein Isoforms; Signal Transduction; Threonine; Transgenes | 2016 |
Methionine restriction inhibits chemically-induced malignant transformation in the BALB/c 3T3 cell transformation assay.
Topics: Animals; BALB 3T3 Cells; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; Folic Acid; Methionine; Methylcholanthrene; Mice; Vitamin B Complex | 2016 |
XIAP RING domain mediates miR-4295 expression and subsequently inhibiting p63α protein translation and promoting transformation of bladder epithelial cells.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Methionine; Mice; Mice, Transgenic; MicroRNAs; Protein Biosynthesis; Protein Domains; Sp1 Transcription Factor; Transcription Factors; Tumor Suppressor Proteins; Up-Regulation; Urinary Bladder; Urinary Bladder Neoplasms; X-Linked Inhibitor of Apoptosis Protein | 2016 |
Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes.
Topics: Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Choline; Diet, High-Fat; Disease Models, Animal; Hep G2 Cells; Hepatic Stellate Cells; Humans; Liver Neoplasms; Male; Methionine; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; RAW 264.7 Cells; Tubulin; Up-Regulation | 2017 |
Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.
Topics: Amino Acid Substitution; Cell Line, Transformed; Cell Transformation, Neoplastic; Chondrocytes; Chromatin; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Lysine; Methionine; Methylation; Mutation; Protein Processing, Post-Translational; Signal Transduction | 2017 |
Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line.
Topics: Aniline Compounds; Apoptosis; Catalase; Cell Transformation, Neoplastic; DNA; DNA Damage; Enzyme Inhibitors; Halogenation; HL-60 Cells; Humans; Hydroquinones; Methionine; Reactive Oxygen Species; Stress, Physiological; Tyrosine | 2012 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors.
Topics: Actin Cytoskeleton; Actins; Alkyl and Aryl Transferases; Animals; Bacterial Proteins; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; Epithelial Cells; Escherichia coli Proteins; Farnesyltranstransferase; Fibroblasts; Genes, ras; Intestinal Mucosa; Methionine; Models, Biological; Protein Isoforms; Protein Kinase C; Protein Prenylation; Protein Processing, Post-Translational; rac1 GTP-Binding Protein; Rats; Signal Transduction | 2003 |
Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1.
Topics: Actins; Adaptor Proteins, Signal Transducing; Adenovirus E1A Proteins; Alkyl and Aryl Transferases; Animals; Antigens, Polyomavirus Transforming; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Farnesyltranstransferase; Fibroblasts; Gene Deletion; Membrane Proteins; Methionine; Mice; Mice, SCID; Nerve Tissue Proteins; Nuclear Proteins; ras Proteins; rhoB GTP-Binding Protein; Stress, Physiological; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2003 |
Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.
Topics: Alkyl and Aryl Transferases; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Genes, Dominant; Intestinal Mucosa; Methionine; Mice; Mutation; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; rhoA GTP-Binding Protein; Transfection; Transforming Growth Factor beta; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2004 |
Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
Topics: Acute Disease; Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Transformation, Neoplastic; Checkpoint Kinase 1; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia, Myeloid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potentials; Methionine; Mitochondria; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Staurosporine; U937 Cells | 2005 |
Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation.
Topics: Animals; Apoptosis; Benzamides; Bone Marrow Cells; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Gene Expression Regulation, Leukemic; Imatinib Mesylate; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Methionine; Mice; Oncogene Proteins v-abl; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Piperazines; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; ras Proteins; RNA-Binding Proteins; Signal Transduction | 2005 |
Analysis of pathological defects in methionine metabolism using a simple mathematical model.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Cystathionine beta-Synthase; Glycine N-Methyltransferase; Homocysteine; Humans; Liver; Methionine; Methionine Adenosyltransferase; Models, Biological; Mutation | 2005 |
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution.
Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine | 2007 |
Inability of anti-epidermal growth factor receptor monoclonal antibody to block "autocrine" growth stimulation in transforming growth factor-secreting melanoma cells.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Humans; Male; Melanoma; Methionine; Mice; Peptides; Receptors, Cell Surface; Transforming Growth Factors | 1984 |
Dexamethasone synergistically induces chemotactic peptide receptor expression in HL-60 cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indomethacin; Methionine; Methyltestosterone; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Progesterone; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
S-adenosylmethionine synthetase in cultured normal and oncogenically-transformed human and rat cells.
Topics: Animals; Carcinoma 256, Walker; Cell Line; Cell Transformation, Neoplastic; Genetic Variation; Humans; Kinetics; Lung; Magnesium; Mammary Neoplasms, Experimental; Methionine; Methionine Adenosyltransferase; Rats; Simian virus 40; Skin; Transferases | 1983 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Enzyme Inhibitors; Methionine; Mice; Ornithine; Putrescine; Spermidine; Spermine; Teratoma | 1984 |
Estrogen induces secretary proteins in transformed mouse Leydig cell in vivo, but not in vitro.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Electrophoresis, Polyacrylamide Gel; Estradiol; Leydig Cell Tumor; Methionine; Mice; Mice, Inbred BALB C; Molecular Weight; Neoplasm Proteins; Sulfur Radioisotopes | 1984 |
Influence of retinoic acid on protein synthesis and transport of L-methionine in cultured L cells.
Topics: Acid Phosphatase; Animals; Biological Transport; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Kinetics; L Cells; Methionine; Mice; Protein Biosynthesis; Tretinoin | 1984 |
Formation and utilization of methionine by rat liver cells in culture.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Homocysteine; Leucine; Liver; Methionine; Rats; Vitamin B 12 | 1983 |
Expression of a variant form of actin and additional polypeptide changes following chemical-induced in vitro neoplastic transformation of human fibroblasts.
Topics: Actins; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Genetic Variation; Humans; Isoelectric Focusing; Methionine; Molecular Weight; Peptide Biosynthesis; Peptide Fragments; Phenylalanine | 1980 |
The elevated requirement for methionine by transformed rat liver epithelial cells in vitro.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media; Homocysteine; Kinetics; Liver; Methionine; Rats | 1980 |
Methionine regulation of N-5-methyltetrahydrofolate: homocysteine methyltransferase and its influence on the growth and protein synthesis in normal, neoplastic, and transformed cells in culture.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Enzyme Induction; Female; Fibroblasts; HeLa Cells; Homocysteine; Homocysteine S-Methyltransferase; Humans; Methionine; Methyltransferases; Pregnancy; Protein Biosynthesis; Rats | 1982 |
A specific biosynthetic marker for immature thymic lymphoblasts. Active synthesis of thymus-leukemia antigen restricted to proliferating cells.
Topics: Animals; Antigens, Ly; Antigens, Neoplasm; Binding Sites; Cell Separation; Cell Transformation, Neoplastic; DNA; Female; Glycoproteins; Lectins; Lymphocyte Activation; Male; Membrane Glycoproteins; Methionine; Mice; Mice, Inbred A; Mice, Inbred C57BL; Peanut Agglutinin; T-Lymphocytes; Thymus Gland | 1982 |
The reversibility of cancer: evidence that malignancy in melanoma cells is gamma-linolenic acid deficiency-dependent.
Topics: Animals; Cattle; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Linoleic Acids; Melanoma; Methionine; Mice; Neoplasms, Experimental; Thymidine | 1982 |
Transport of methionine by normal and transformed rat embryo fibroblasts.
Topics: Animals; Animals, Newborn; Biological Transport; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Female; Fibroblasts; Kinetics; Methionine; Pregnancy; Proteins; Rats; Rats, Inbred Strains | 1982 |
Effect of methionine replacement by homocysteine on the growth of cells.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Culture Media; Homocysteine; Humans; Methionine; Mice; Neoplasms; Rats | 1980 |
Gene expression in murine hybrids exhibiting different morphologies and tumorigenic properties.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Female; Gene Expression Regulation; Hybrid Cells; Methionine; Mice; Ovary; Peptides; Proteins | 1981 |
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Methionine; Molecular Sequence Data; Oligopeptides; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Transferases | 1995 |
Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2.
Topics: Adenovirus E1A Proteins; Adenoviruses, Human; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Conserved Sequence; DNA Mutational Analysis; Humans; KB Cells; Kidney; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Rats; Retinoblastoma Protein; Structure-Activity Relationship | 1994 |
Activation of the leukocyte plastin gene occurs in most human cancer cells.
Topics: Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cloning, Molecular; DNA Primers; Escherichia coli; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Membrane Glycoproteins; Methionine; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Neoplasms; Phosphoproteins; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1994 |
The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.
Topics: Amino Acid Sequence; Animals; Autoradiography; Baculoviridae; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cricetinae; DNA Primers; DNA, Complementary; Gene Expression; Gene Rearrangement; Humans; MAP Kinase Kinase Kinases; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Open Reading Frames; Peptide Chain Initiation, Translational; Phosphoproteins; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured | 1993 |
p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system.
Topics: Animals; Avian Sarcoma Viruses; Benzoquinones; Cadherins; Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; Fibroblasts; Lactams, Macrocyclic; Methionine; Oncogene Protein pp60(v-src); Phosphates; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1993 |
Conditional immortalization of human endometrial stromal cells with a temperature-sensitive simian virus 40.
Topics: Antigens, Polyomavirus Transforming; Base Sequence; Cell Adhesion; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Endometrium; Female; Humans; Karyotyping; Kinetics; Methionine; Molecular Sequence Data; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Simian virus 40; Temperature; Time Factors; Transfection | 1993 |
The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; Cysteine; Genes, ras; GTP-Binding Proteins; Methionine; Mevalonic Acid; Mice; Molecular Sequence Data; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); rab5 GTP-Binding Proteins; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Sulfur Radioisotopes; Transfection; Tritium | 1993 |
Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Brain; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Design; Enzyme Inhibitors; Genes, ras; Glutamates; Isoquinolines; Methionine; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Oncogene Protein p21(ras); Protein Prenylation; Rats; Swine; Tetrahydroisoquinolines; Transfection; Transferases; Tumor Cells, Cultured; Valine | 1996 |
The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts.
Topics: Alkyl and Aryl Transferases; Animals; Apoptosis; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Embryo, Mammalian; Enzyme Inhibitors; Farnesyltranstransferase; Fibroblasts; Genes, myc; Genes, ras; Kinetics; Methionine; Radiation-Sensitizing Agents; Rats; Transfection; Transferases; Urinary Bladder Neoplasms | 1996 |
Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Benzamides; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Diterpenes; DNA; Enzyme Inhibitors; Farnesol; Fibroblasts; G1 Phase; Genes, ras; GTP-Binding Proteins; Lovastatin; Methionine; Mevalonic Acid; Mice; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; rap GTP-Binding Proteins; ras Proteins; Resting Phase, Cell Cycle; S Phase; Transferases | 1996 |
Regulation of the transcription factor AP-1 in benign and malignant mouse keratinocyte cells.
Topics: Animals; Antibodies; Blotting, Northern; Blotting, Western; Cell Transformation, Neoplastic; DNA; Electrophoresis, Polyacrylamide Gel; Keratinocytes; Methionine; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Phosphorus Radioisotopes; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured | 1997 |
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential.
Topics: 3T3 Cells; Animals; Carcinoma, Medullary; Cell Transformation, Neoplastic; Drosophila Proteins; Enzyme Activation; Methionine; Mice; Multiple Endocrine Neoplasia Type 2a; Multiple Endocrine Neoplasia Type 2b; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship; Thyroid Neoplasms; Transfection | 1997 |
Induction of parathyroid hormone-related peptide by the Ras oncogene: role of Ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia of malignancy.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; Female; Genes, ras; Hypercalcemia; Methionine; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasms, Experimental; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphoinositide-3 Kinase Inhibitors; Protein Biosynthesis; Protein Prenylation; Rats; Rats, Inbred F344; Transfection | 1997 |
Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.
Topics: Alkyl and Aryl Transferases; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Farnesyltranstransferase; Genes, ras; Genes, src; Methionine; Mutation; Proto-Oncogene Proteins c-raf; Rats; Up-Regulation | 1998 |
Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Contact Inhibition; Culture Media, Serum-Free; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; Genes, jun; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; NF-kappa B; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphatidylinositol 3-Kinases; Protein Prenylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; ras Proteins; Receptor Protein-Tyrosine Kinases; Receptor, EphB4; Receptors, Eph Family; rhoA GTP-Binding Protein; Serum Response Factor; Signal Transduction; Tumor Stem Cell Assay | 2000 |
Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbeta.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Cell Division; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Methionine; Mice; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2000 |
Glucose regulates protein catabolism in ras-transformed fibroblasts through a lysosomal-dependent proteolytic pathway.
Topics: 3T3 Cells; Acetylcysteine; Animals; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Fibroblasts; Genes, ras; Glucose; Humans; Kinetics; Kirsten murine sarcoma virus; L-Lactate Dehydrogenase; Lysosomes; Methionine; Methylamines; Mice; Protein Biosynthesis; Proteins; Tumor Cells, Cultured | 2001 |
Antitumor activity of ER-51785, a new peptidomimetic inhibitor of farnesyl transferase: synergistic effect in combination with paclitaxel.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Humans; Methionine; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms; Protein Processing, Post-Translational; Transplantation, Heterologous; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2001 |
Transcription of the Rous sarcoma virus genome in vitro and in vivo.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; DNA, Viral; Ducks; Genes; Methionine; Mice; RNA-Directed DNA Polymerase; RNA, Transfer; RNA, Viral; Templates, Genetic; Transcription, Genetic | 1975 |
Decrease in membrane-associated actin of fibroblasts after transformation by Rous sarcoma virus.
Topics: Actins; Animals; Avian Sarcoma Viruses; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Fibroblasts; Methionine; Temperature | 1975 |
Topography of substrate-attached glycoproteins from normal and virus-transformed cells.
Topics: Animals; Autoradiography; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Fibroblasts; Glucosamine; Glycoproteins; Methionine; Mice; Mice, Inbred BALB C; Simian virus 40 | 1975 |
Alterations in membrane polypeptides of chick embryo fibroblasts induced by transformation with avian sarcoma viruses.
Topics: Alpharetrovirus; Animals; Autoradiography; Avian Sarcoma Viruses; Cell Fractionation; Cell Membrane; Cell Transformation, Neoplastic; Chick Embryo; Culture Techniques; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Methionine; Molecular Weight; Mutation; Neoplasm Proteins; Peptides; Proteins; Sulfur Radioisotopes; Temperature | 1975 |
Synthesis, surface deposition, and secretion of immunoglobulins by Abelson virus-transformed lymphosarcoma cell lines.
Topics: Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Immunoglobulin G; Immunoglobulin gamma-Chains; Immunoglobulin Light Chains; Immunoglobulin M; Immunoglobulin mu-Chains; Kinetics; Lymphoma, Non-Hodgkin; Methionine; Protein Biosynthesis; Proteins; Receptors, Antigen, B-Cell; Retroviridae | 1975 |
Inhibition by methioninyl adenylate of focus formation by Rous sarcoma virus.
Topics: Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Contact Inhibition; Dose-Response Relationship, Drug; Methionine; Methionine-tRNA Ligase; Neoplasm Proteins; Virus Replication | 1975 |
High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma 256, Walker; Cell Line; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Methionine; Simian virus 40 | 1976 |
Methionine biosynthesis in normal and transformed fibroblasts.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Simian virus 40 | 1977 |
The sequence specificity of vertebrate DNA methylation.
Topics: Animals; Base Sequence; Biological Evolution; Cell Fractionation; Cell Line; Cell Transformation, Neoplastic; Cytosine; Deoxyribonucleotides; DNA; HeLa Cells; L Cells; Methionine; Methylation; Polyomavirus; Species Specificity; Vertebrates | 1977 |
5-methyltetrahydrofolate: synthesis and utilization in normal and SV40-transformed BHK-21 cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Folic Acid; Homocysteine; Kidney; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Simian virus 40; Tetrahydrofolates; Vitamin B 12 | 1977 |
Inhibition of tRNA methylation in vitro and in whole cells by an oncostatic S-adenosyl-homocysteine (SAH) analogue: 5'-deoxy 5'-S-isobutyl adenosine (SIBA).
Topics: Avian Sarcoma Viruses; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cell-Free System; Deoxyadenosines; Dose-Response Relationship, Drug; Methionine; RNA, Transfer; S-Adenosylhomocysteine; Thionucleosides; tRNA Methyltransferases | 1978 |
Comparison of polypeptides from cultured human fibroblasts and sarcoma cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Galactose; Glycoproteins; Humans; Mannose; Methionine; Molecular Weight; Neoplasm Proteins; Peptides; Sarcoma, Experimental; Simian virus 40 | 1978 |
Multiple forms of polyoma virus tumor antigens from infected and transformed cells.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Methionine; Mice; Molecular Weight; Peptides; Polyomavirus; Viral Proteins | 1979 |
An increased requirement for methionine by transformed rat liver epithelial cells in vitro.
Topics: Betaine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media; Homocysteine; Methionine | 1978 |
Inhibition of initiation of protein synthesis in mammalian tissue culture cells by L-1-tosylamido-2-phenylethyl chloromethyl ketone.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Depression, Chemical; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Fibroblasts; HeLa Cells; Humans; Kinetics; Methionine; Mice; Molecular Weight; Neoplasm Proteins; Peptide Chain Initiation, Translational; Phenylalanine; Plasmacytoma; Polyribosomes; Ribosomes; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Time Factors; Tosyl Compounds | 1975 |
Reversal of divergent differentiation by ras oncogene-mediated transformation.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Fluorescent Antibody Technique; Genes, ras; Granulosa Cells; Keratins; Kirsten murine sarcoma virus; Methionine; Progesterone; Rats; Rats, Inbred F344; Transfection | 1992 |
Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polyacrylamide Gel; Methionine; Mice; Mutation; Oncogene Protein p21(ras); Oncogene Protein pp60(v-src); Oncogene Proteins v-sis; Oncogene Proteins, Viral; Phosphates; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Retroviridae Proteins, Oncogenic; Serine; Signal Transduction; Transcriptional Activation | 1992 |
Comparison of three methods for detecting tyrosine-phosphorylated proteins.
Topics: Animals; Antigen-Antibody Complex; Autoradiography; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chromatography, Affinity; Fibroblasts; Glycoproteins; Immunoblotting; Methionine; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Radioisotope Dilution Technique; Sulfur Radioisotopes; Tyrosine | 1991 |
Influence of diet on breast cancer size and morphology in rats treated with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Division; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methionine; Rats; Rats, Inbred Strains | 1991 |
Cell-shape regulation and matrix protein p52 content in phenotypic variants of ras-transformed rat kidney fibroblasts. Functional analysis and biochemical comparison of p52 with proteins implicated in cell-shape determination.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, ras; Glycoproteins; Humans; Kidney; Kinetics; Methionine; Rats; Transfection | 1991 |
Stage transitions in B-lymphocyte differentiation correlate with limited variations in nuclear proteins.
Topics: Animals; B-Lymphocytes; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Gel, Two-Dimensional; Methionine; Nuclear Proteins | 1991 |
Novel ATP-binding heat-inducible protein of Mr = 37,000 that is sensitive to transformation in BALB/3T3 cells.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Calcimycin; Carrier Proteins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum Chaperone BiP; Fibroblasts; Heat-Shock Proteins; Methionine; Mice; Mice, Inbred BALB C; Precipitin Tests; Sepharose; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tunicamycin | 1990 |
Complete transformation of embryonal rat fibroblasts by polyomavirus occurs during passage in vitro.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Embryo, Mammalian; Fibroblasts; Genes, ras; Genes, Viral; Methionine; Plasmids; Polyomavirus; Protein Biosynthesis; Proteins; Rats; Thymidine; Transfection | 1990 |
Selective potentiation of c-fps/fes transforming activity by a phosphatase inhibitor.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; ErbB Receptors; Harvey murine sarcoma virus; Helper Viruses; Methionine; Mice; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Vanadates | 1990 |
Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Dexamethasone; Enzyme Induction; Kinetics; Methionine; Mice; Mutation; Oncogene Protein pp60(v-src); Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Temperature; Tetradecanoylphorbol Acetate | 1990 |
Increased secretory activity and estradiol receptor expression are among other relevant aspects of MCF-7 human breast tumor cell growth which are expressed only in the absence of serum.
Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Culture Media; Embryo, Mammalian; Epithelium; Female; Fibroblasts; Humans; Immunohistochemistry; Insulin; Methionine; Microscopy, Electron; Proteins; Rats; Receptors, Estradiol; Serum Albumin, Bovine; Sulfur Radioisotopes; Tumor Cells, Cultured | 1990 |
Immunochemical comparison of transformation-associated protein and secreted phosphoprotein.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Electrophoresis, Polyacrylamide Gel; Immunosorbents; Iodine Radioisotopes; Kidney; Methionine; Mice; Oncogene Proteins, Viral; Osteopontin; Precipitin Tests; Rabbits; Rats; Sialoglycoproteins; Sodium Dodecyl Sulfate; Sulfur Radioisotopes; Temperature | 1990 |
The c-ets-1 proto-oncogene has oncogenic activity and is positively autoregulated.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Southern; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation; Genetic Vectors; Homeostasis; Methionine; Mice; Mice, Nude; Molecular Sequence Data; Precipitin Tests; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; RNA, Messenger; Sulfur Radioisotopes; Transcription Factors; Transcription, Genetic; Transfection | 1990 |
Biosynthesis of alkaline phosphatase during differentiation of the human colon cancer cell line Caco-2.
Topics: Alkaline Phosphatase; Biomarkers, Tumor; Cell Line, Transformed; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Humans; Methionine; Microvilli; Molecular Weight; Precipitin Tests; Sulfur Radioisotopes; Tumor Cells, Cultured | 1990 |
L-azaserine induced preneoplasia in the rat pancreas. A morphometric study of dietary manipulation (lipotrope deficiency) and ultrastructural differentiation.
Topics: Animals; Azaserine; beta-Lipotropin; Cell Transformation, Neoplastic; Choline Deficiency; Cytoplasmic Granules; Diet; Enzyme Precursors; Folic Acid Deficiency; Male; Methionine; Microscopy, Electron; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Lew; Vitamin B 12 Deficiency | 1990 |
Keratin expression of both chemically and virally transformed human epidermal keratinocytes during the process of neoplastic conversion.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epidermal Cells; Epidermis; Humans; Keratins; Male; Methionine; Mice; Mice, Nude; Molecular Weight; Neoplasm Transplantation; Simian virus 40; Skin | 1986 |
Spontaneous and 5-azacytidine-induced revertants of methionine-dependent tumor-derived and H-ras-1-transformed cells.
Topics: Animals; Azacitidine; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Culture Media; Ethyl Methanesulfonate; Homocysteine; Methionine; Methylation; Oncogenes; Tumor Cells, Cultured | 1989 |
Agarose-selected variants of two human tumor cell lines exhibit altered methionine auxotrophy.
Topics: Cell Line; Cell Transformation, Neoplastic; Genetic Variation; Homocysteine; Humans; Melanoma; Methionine; Neuroblastoma; Nucleic Acids; S-Adenosylmethionine; Sepharose; Tumor Cells, Cultured | 1989 |
Methionine-sensitive glycolysis in transformed cells.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Cycloheximide; Glycolysis; HeLa Cells; Humans; Kidney; Kinetics; Kirsten murine sarcoma virus; Methionine; Mice; Rats; Sarcoma Viruses, Murine | 1985 |
Decreased methylation rates of DNA in SV40-transformed human fibroblasts.
Topics: Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Methionine; Methylation; S-Adenosylmethionine; Simian virus 40 | 1986 |
Correlation between H-ras p21TLeu61 protein content and tumorigenicity of NIH3T3 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Codon; DNA, Neoplasm; Genes, ras; Leucine; Methionine; Mice; Mice, Nude; Mutation; Oncogene Protein p21(ras); Skin Neoplasms; Transfection | 1988 |
Effect of growth factors and methionine on glycolysis and methionine transport in rat fibroblasts and fibroblasts transfected with myc and ras genes.
Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Glycolysis; Growth Substances; GTP-Binding Proteins; Insulin; Insulin-Like Growth Factor I; Methionine; Oncogenes; Peptides; Rats; Transfection; Transforming Growth Factors | 1986 |
Loss of the oncogene from human H-ras-1-transfected NIH/3T3 cells grown in the presence of excess methionine.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Culture Media; Female; Humans; Methionine; Mice; Mice, Nude; Oncogenes; Transfection | 1986 |
Effects of epidermal growth factor on transferrin receptor phosphorylation and surface expression in malignant epithelial cells.
Topics: Animals; Antibodies; Binding Sites; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; Epithelium; ErbB Receptors; Methionine; Phosphorylation; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Vanadates | 1987 |
Ethionine in the analysis of the possible separate roles of methionine and choline deficiencies in carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Ethionine; Liver Neoplasms, Experimental; Methionine; Models, Biological | 1986 |
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Methionine; Rats; S-Adenosylhomocysteine | 1986 |
Methionine metabolism defect in cells transfected with an activated HRAS1 oncogene.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Humans; Liver; Methionine; Nucleic Acid Hybridization; Oncogenes; Plasmids; Rats; Transcription, Genetic; Transformation, Genetic | 1987 |
Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes.
Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Cell Transformation, Neoplastic; Cycloheximide; Dose-Response Relationship, Drug; Fibroblasts; Glycolysis; Methionine; Oncogenes; Peptides; Platelet-Derived Growth Factor; Rats; Transfection; Transforming Growth Factors | 1985 |
Secreted phosphoprotein markers for neoplastic transformation of human epithelial and fibroblastic cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epithelium; Fibroblasts; Humans; Methionine; Mice; Mice, Inbred BALB C; Molecular Weight; Phosphoproteins | 1985 |
Altered transfer RNA methylase patterns induced by an avian oncogenic virus.
Topics: Animals; Avian Leukosis Virus; Carbon Isotopes; Cell Transformation, Neoplastic; Chickens; Chromatography, Ion Exchange; Chromatography, Paper; Deoxyribonucleases; Enzyme Induction; Escherichia coli; Leukemia, Experimental; Liver; Methionine; Nucleosides; RNA, Bacterial; RNA, Transfer; Spleen; Transferases | 1969 |
Analysis of simian virus 40-induced transformation of hamster kidney tissue in vitro. 8. Induction of infectious simian virus 40 from virogenie transformed hamster cells by amino acid deprivation or cycloheximide treatment.
Topics: Animals; Arginine; Canavanine; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Clone Cells; Cricetinae; Culture Media; Cycloheximide; DNA, Neoplasm; Haplorhini; Kidney; Leucine; Methionine; Neoplasm Proteins; Puromycin; Simian virus 40; Thymidine; Tritium; Viral Proteins; Virus Cultivation; Virus Replication | 1972 |
Secretion of RNA by normal and transformed cells.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Paper; Formates; Hydrolysis; In Vitro Techniques; Methionine; Methylation; Nucleotides; RNA; RNA, Neoplasm; RNA, Ribosomal; Simian virus 40; Thymidine; Trichloroacetic Acid; Tritium; Uridine | 1972 |
Transfer RNA activities of Rous sarcoma and Rous associated viruses.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Avian Leukosis Virus; Avian Sarcoma Viruses; Carbon Isotopes; Cell Transformation, Neoplastic; Chick Embryo; Fibroblasts; Liver; Methionine; RNA, Transfer; RNA, Viral; Tritium | 1973 |
Plasma membrane proteins of normal and Rous sarcoma virus-transformed chick-embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Fractionation; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Methionine; Molecular Weight; Neoplasm Proteins; Peptides; Protein Biosynthesis; Proteins; Sulfur Isotopes | 1973 |
DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).
Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Paper; Clone Cells; Cricetinae; Cytidine; Cytosine; Deoxyuridine; DNA; Kidney; Methionine; Methylation; Polyomavirus; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Radioimmunoassay of avian RNA tumor virus group-specific antigen.
Topics: Animals; Antigens, Viral; Avian Leukosis Virus; Avian Sarcoma Viruses; Binding Sites, Antibody; Cell Transformation, Neoplastic; Chick Embryo; Chloramines; Chromatography, Gel; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Glucosamine; Immune Sera; Immunoglobulin G; Iodine Radioisotopes; Isoelectric Focusing; Methionine; Methods; Rabbits; Radioimmunoassay; Sulfur Radioisotopes; Tritium; Viral Proteins | 1973 |
Differential methylation of mitochondrial and nuclear DNA in cultured mouse, hamster and virus-transformed hamster cells. In vivo and in vitro methylation.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chromatography, Thin Layer; Cricetinae; Cytosine; Deoxycytidine; DNA; DNA, Mitochondrial; Escherichia coli; Kidney; L Cells; Methionine; Methylation; Methyltransferases; Mice; Phosphorus Radioisotopes; Polyomavirus; Subcellular Fractions; Tritium | 1973 |
Selective incorporation of host cell methionyl-transfer RNA by RNA tumor viruses.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Avian Sarcoma Viruses; Binding Sites; Carbon Radioisotopes; Cell Transformation, Neoplastic; Chick Embryo; Chickens; Chromatography, DEAE-Cellulose; Escherichia coli; Fibroblasts; Liver; Magnesium; Methionine; Molecular Weight; Ribosomes; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Species Specificity; Spectrophotometry, Ultraviolet; Transfer RNA Aminoacylation; Tritium | 1974 |
Vesicular stomatitis virus envelope glycoprotein alterations induced by host cell transformation.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Paper; Cricetinae; Electrophoresis, Polyacrylamide Gel; Fucose; Glucosamine; Glucosidases; Glycopeptides; Glycoproteins; Kidney; Mannose; Methionine; Molecular Weight; Oligosaccharides; Polyomavirus; Sulfur Radioisotopes; Tritium; Vesicular stomatitis Indiana virus; Viral Proteins | 1974 |
Cyclic GMP and cyclic AMP levels in normal and transformed fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic GMP; DNA; Fibroblasts; Kidney; Leucine; Methionine; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Prostaglandins; Simian virus 40; Tritium | 1974 |
Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses.
Topics: Alpharetrovirus; Amino Acyl-tRNA Synthetases; Animals; Arginine; Aspartic Acid; Avian Sarcoma Viruses; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cell-Free System; Chick Embryo; Chickens; Chromatography; Culture Techniques; Fibroblasts; Liver; Lysine; Methionine; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Satellite Viruses; Tritium | 1974 |
An SV40-induced initiation factor for protein synthesis concerned with the regulation of permissiveness.
Topics: Adenoviridae; Animals; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Haplorhini; Kidney; Methionine; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Messenger; RNA, Viral; Simian virus 40; Tritium | 1974 |
Cell surface proteins of NIL1 hamster fibroblasts labeled by a galactose oxidase, tritiated borohydride method.
Topics: Alcohol Oxidoreductases; Animals; Borohydrides; Carbon Radioisotopes; Cell Count; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cricetinae; Electrophoresis, Disc; Fibroblasts; Galactose; Glucosamine; Glycoproteins; Iodine; Methionine; Molecular Weight; Neuraminidase; Oncogenic Viruses; Peroxidases; Sarcoma, Experimental; Sulfur Radioisotopes; Tritium; Trypsin | 1974 |
Comparison of soluble RNA methylase capacity in paired neoplastic and nonneoplastic cell lines in vitro.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Escherichia coli; Methionine; Methylation; Mice; Neoplasms; RNA, Neoplasm; RNA, Transfer; Transferases | 1969 |
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Inhibitors of chemical carcinogens as probes for molecular targets: DNA as decisive receptor for metabolite from N-hydroxy-N-2-fluorenylacetamide.
Topics: Acetamides; Acetanilides; Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Chloramphenicol; DNA; Drug Antagonism; Fluorenes; Guanine; Hydroxamic Acids; Indoles; Inosine; Liver; Male; Methionine; Proteins; Rats; Rats, Inbred Strains; RNA, Ribosomal; Stimulation, Chemical; Subcellular Fractions; Toluidines; Tryptophan; Tyrosine | 1969 |
Substances with antineoplastic effect. XLII. The influence of MBA on incorporation of some amino-acids in the proteins of Yoshida ascites rat sarcoma cells.
Topics: Acrylates; Amino Acids; Animals; Antineoplastic Agents; Autoradiography; Carbon Isotopes; Cell Transformation, Neoplastic; Glutamates; Glycine; Injections, Intraperitoneal; Methionine; Neoplasm Proteins; Phenylalanine; Rats; Sarcoma, Yoshida | 1970 |
Comparison of methyl-labeled tRNA in a neoplastic cell line with a paired non-neoplastic control.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chemistry Techniques, Analytical; Chromatography; Culture Techniques; Embryo, Mammalian; Methionine; Methylation; Mice; Neoplasms, Experimental; RNA, Transfer; Tritium | 1970 |
Chemical carcinogens and RNA.
Topics: Acetates; Amides; Animals; Base Sequence; Benzene Derivatives; Carbon Isotopes; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Ethionine; Fluorenes; Hot Temperature; Lactones; Methionine; Mutation; Nitrosamines; Rats; RNA, Transfer | 1971 |