methionine has been researched along with Cancer of Lung in 104 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (19.23) | 18.7374 |
1990's | 27 (25.96) | 18.2507 |
2000's | 21 (20.19) | 29.6817 |
2010's | 25 (24.04) | 24.3611 |
2020's | 11 (10.58) | 2.80 |
Authors | Studies |
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Chen, X; Du, H; He, X; Li, P; Pan, Y; Ren, K; Wang, T; Xie, W; Yang, H; Yang, M; Yu, A; Zhang, W; Zhao, Y; Zheng, H; Zhou, Z | 1 |
Calandriello, L; Caldarella, C; Cancellieri, A; Lococo, F; Martino, A; Taralli, S | 1 |
Abliz, Z; Chen, Y; Li, C; Qian, M; Yao, L; Zhou, J; Zhou, W | 1 |
Chou, PJ; Hudlikar, RR; Kong, AN; Li, S; Sarwar, MS; Su, X; Wang, L; Wang, Y; Wu, R | 1 |
Chang, QH; Chang, R; Mao, T; Wang, N; Xu, ZJ; Ye, Y; Zhang, DY; Zhang, YC | 1 |
Beverly, LJ; Clem, BF; Filho, FSL; Hallam, SJ; Johnson, FD; Lam, S; Lam, WL; Leung, JM; Lockwood, WW; Marshall, EA; Nislow, C; Noonan, AJC; Pewarchuk, ME; Shah, PP; Stewart, GL; Vega, AA; Vucic, EA; Yang, J | 1 |
Alloisio, M; Bottoni, E; Castello, A; Ceresoli, GL; Crepaldi, A; Ferraroli, GM; Lopci, E; Novellis, P; Perrino, M; Rahal, D; Testori, A; Veronesi, G; Voulaz, E; Zucali, PA | 1 |
Calderoni, L; Castellucci, P; Fanti, S; Telo, S; Vichi, S; Zagni, F | 1 |
Bouvet, M; Endo, I; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Kumamoto, T; Matsuyama, R; Miyake, K; Nishino, H; Sugisawa, N; Yamamoto, J | 1 |
Aoki, Y; Bouvet, M; Endo, I; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Matsuyama, R; Miyake, K; Nishino, H; Sugisawa, N; Sun, YU; Yamamoto, J | 1 |
Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
Agana, BA; Amann, JM; Arasada, RR; Cacciato, N; Carbone, DP; Gerstein, MB; Kaufman, JM; Koenig, MJ; Navarro, FCP; Oakes, C; Sharpnack, MF; Wang, WZ; Weigel, C; Wysocki, VH | 1 |
Albanes, D; Arslan, AA; Blot, WJ; Bolton, JH; Brennan, P; Buring, JE; Butler, LM; Cai, Q; Caporaso, NE; Ericson, U; Fanidi, A; Freedman, ND; Gao, YT; Gaziano, JM; Giles, GG; Giovannucci, E; Grankvist, K; Haiman, CA; Han, J; Hodge, AM; Johansson, M; Koh, WP; Krokstad, S; Lan, Q; Langhammer, A; Le Marchand, L; Lee, IM; Li, H; Manjer, J; McCullough, ML; Midttun, Ø; Muller, DC; Næss, M; Pettinger, M; Prentice, R; Purdue, M; Relton, C; Sesso, HD; Severi, G; Shu, XO; Smith-Warner, SA; Stampfer, MJ; Stevens, VL; Thomsen, CA; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, R; Weinstein, SJ; Wilkens, LR; Wu, J; Xiang, YB; Yuan, JM; Zeleniuch-Jacquotte, A; Zhang, X; Zheng, W; Ziegler, RG | 1 |
Annunziata, S; Chiesa, S; Cuccaro, A; DʼAlò, F; Rizzo, A | 1 |
Barnes, TA; Leighl, NB; O'Kane, GM | 1 |
Bourien, H; Corre, R; Lena, H; Lespagnol, A; Leveiller, G; Prigent, A; Ricordel, C | 1 |
Du, Y; Huang, Y; Ma, Y; Shi, H; Zhou, Y | 1 |
Chen, K; Christiani, DC; Liu, H; Liu, Z; Luo, S; Moorman, PG; Patz, EF; Shen, S; Su, L; Wei, Q | 1 |
Ang, HY; Basri, N; Chew, HY; Chong, PKW; Choo, LSK; Hillmer, AM; Ho, YS; Jiang, X; Lee, JHJ; Lim, B; Lim, TKH; Lim, WT; Ma, S; Peh, KLE; Takano, A; Tam, WL; Tan, DSW; Tan, EH; Teo, CC; Wang, Z; Wu, Z; Yip, LY; Yu, Q; Yuan, J | 1 |
Agudo, A; Allen, NE; Baltar, VT; Barricarte, A; Boeing, H; Boshuizen, H; Boutron-Ruault, MC; Brennan, P; Bueno-de-Mesquita, B; Castaño, JM; Chuang, SC; Clavel-Chapelon, F; Crowe, F; Fagherazzi, G; Ferrari, P; Gallo, V; Hallmans, G; Jenab, M; Johansson, M; Kaaks, R; Khaw, KT; Krogh, V; Lagiou, P; Larrañaga, N; Masala, G; Midttun, Ø; Navarro, C; Norat, T; Onland-Moret, NC; Panico, S; Rasmuson, T; Relton, C; Riboli, E; Rodríguez, L; Rohrmann, S; Roswall, N; Sacerdote, C; Slimani, N; Tjønneland, A; Trichopoulos, D; Trichopoulou, A; Tumino, R; Ueland, PM; van Gils, CH; Vineis, P; Wareham, N; Weikert, C; Xun, WW | 1 |
Boone, C; Di Giandomenico, D; Lucisano, G; Mosca, MG; Parsons, AB; Porcu, G; Ragnini-Wilson, A | 1 |
Han, JY; Hwang, JA; Kim, HT; Kim, JH; Kim, SH; Lee, GK; Lee, JS; Lee, Y; Lee, YS; Nam, BH; Yun, T; Zhang, W | 1 |
Asano, H; Furukawa, M; Hagiwara, K; Hashida, S; Miyoshi, S; Shien, K; Soh, J; Tanaka, T; Toyooka, S; Tsukuda, K; Yamamoto, H | 1 |
Dai, B; Fang, B; Gao, W; Gold, KA; Heymach, JV; Hofstetter, WL; Lu, H; Minna, J; Ou, Z; Roth, JA; Swisher, SG; Wang, L; Wang, M; Wu, S; Zhang, L | 1 |
Bryan, MC; Burdick, DJ; Chan, BK; Chen, Y; Dotson, J; Eigenbrot, C; Hanan, EJ; Heald, RA; Heffron, TP; Jackson, PS; La, H; Lainchbury, MD; Malek, S; Purkey, HE; Schaefer, G; Schmidt, S; Seward, EM; Sideris, S; Tam, C; Wang, S; Yeap, SK; Yen, I; Yin, J; Yu, C; Zilberleyb, I | 1 |
Fan, XX; Jiang, ZH; Leung, EL; Liu, L; Liu, ZQ; Lu, LL; Tin, VP; Wong, MP; Yao, XJ; Yau, LF; Zhou, YL | 1 |
Chen, S; Hui, L; Jia, Q; Ma, M; Sang, C; Wang, D; Wang, M; Wang, X | 1 |
Dong, ZY; Gao, HF; Gou, LY; Li, AN; Liu, SY; Lou, NN; Su, J; Wu, YL; Xie, Z; Xu, CR; Yan, HH; Yang, JJ; Zhang, XC; Zhong, WZ; Zhou, Q | 1 |
Belka, C; Bullinger, D; Fux, R; Gleiter, CH; Kammerer, B; Laufer, S; Nicholson, G; Plontke, S | 1 |
Chang, CP; Hsieh, HJ; Lee, CY; Lin, KH; Lin, SH; Wang, SJ | 1 |
Iwama, T; Kako, N; Kanematsu, M; Matsuo, M; Miwa, K; Nishibori, H; Sakurai, K; Shinoda, J; Yano, H | 1 |
Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y | 1 |
Agudo, A; Allen, NE; Barricarte, A; Boeing, H; Boffetta, P; Boutron-Ruault, MC; Brennan, P; Bueno-de-Mesquita, HB; Clavel-Chapelon, F; Crowe, F; Fagherazzi, G; Gallo, V; Hallmans, G; Jenab, M; Johansson, M; Kaaks, R; Khaw, KT; Krogh, V; Lagiou, P; Larrañaga, N; Masala, G; Midttun, Ø; Navarro, C; Norat, T; Nygård, O; Panico, S; Peeters, PH; Rasmuson, T; Relton, C; Riboli, E; Rodríguez, L; Rohrmann, S; Ros, MM; Sacerdote, C; Sánchez, MJ; Slimani, N; Trichopoulos, D; Trichopoulou, A; Tumino, R; Ueland, PM; van Gils, CH; Vineis, P; Vollset, SE; Wareham, N; Weikert, C | 1 |
Hackl, S; Kramer, M; Siska, P; Weber, F; Wesierska-Gádek, J; Zulehner, N | 1 |
Akita, K; Aoki, S; Chiba, Y; Fuji, M; Hosoya, N; Ishii, Y; Ishikawa, H; Kawai, K; Nakajima, M; Ohsaka, T; Okajima, T; Onuma, K; Saeki, Y; Sato, T; Senawongse, P; Shoun, H; Sugawara, Y; Sugiyama, S; Suzuki, T; Takahashi, M; Tsuboi, M; Urushiyama, A; Yagi, S; Yamagishi, K; Yamanaka, T | 1 |
Baglietto, L; Bassett, JK; English, DR; Giles, GG; Hodge, AM; Hopper, JL; Severi, G | 1 |
Chang, S; Ding, J; Ding, K; Geng, M; Liu, Y; Lu, X; Luo, J; Pei, D; Ren, X; Tu, Z; Xu, S; Xu, T; Xu, Y; Zhang, L; Zhang, Z | 1 |
El-Sayed, AS; Nassrat, HM; Shouman, SA | 1 |
Beeghly-Fadiel, A; Cai, Q; Chow, WH; Gao, YT; Ji, BT; Li, H; Shrubsole, MJ; Shu, XO; Takata, Y; Yang, G; Zheng, W | 1 |
Bloom, JW; Carlsson, P; Carlstedt-Duke, J; Kunz, S; Miesfeld, RL; Sandoval, R | 1 |
Hamilton, AD; Kastens, E; Lantry, LE; Liu, G; Lubet, RA; Sebti, SM; Wang, Y; You, M; Zhang, Z | 1 |
Ahmad, A; Allen, RH; Panayiotidis, MI; Stabler, SP; White, CW | 1 |
Aoki, T; Higashi, T; Hiraoka, M; Ishimori, T; Konishi, J; Mamede, M; Mukai, T; Nagata, Y; Nakamoto, Y; Negoro, Y; Saga, T | 1 |
Reddy, GK | 1 |
Bell, DW; Brannigan, BW; Godin-Heymann, N; Gore, I; Haber, DA; Mohapatra, G; Mulloy, R; Okimoto, RA; Settleman, J; Sharma, SV; Sordella, R | 1 |
Li, K; Pardinas, JR; Xiao, L; Zhang, J | 1 |
Aoe, K; Aoe, M; Asano, H; Date, H; Ichihara, S; Inukai, M; Ito, S; Kiura, K; Ouchida, M; Shimizu, N; Soh, J; Suehisa, H; Toyooka, S | 1 |
Kaji, H; Kanegae, K; Kimura, K; Kuge, Y; Nakano, I; Okamoto, S; Shiga, T; Tamaki, N; Zhao, S | 1 |
Abe, Y; Fujiwara, T; Fukuda, H; Hatazawa, J; Ito, K; Ito, M; Iwata, R; Kubota, K; Matsuzawa, T; Yoshioka, S | 2 |
Dean, PN; George, YS; Gray, JW; Groppi, V; Look, M; Pallavicini, MG | 1 |
Joensuu, H; Lehikoinen, P; Leskinen, S; Lindholm, P; Någren, K; Ruotsalainen, U; Teräs, M | 1 |
Bülow, J; Hansen, OP; Nielsen, OJ; Ovesen, L; Sengeløv, H; Simonsen, L | 1 |
Akashi, Y; Fukumura, T; Ichiya, Y; Kuwabara, Y; Masuda, K; Sasaki, M; Yoshida, T | 1 |
Ho, IC; Lee, TC | 1 |
Arai, T; Hara, T; Iio, M; Miyazawa, H | 1 |
Fujiwara, T; Fukuda, H; Ido, T; Ishiwata, K; Ito, M; Kubota, K; Tada, M; Yamada, S | 1 |
Huovinen, R; Lehikoinen, P; Leskinen-Kallio, S; Någren, K; Ruotsalainen, U; Teräs, M | 1 |
McDonald, FJ; Welsh, MJ | 1 |
Cano, A; Caulín, C; Fabra, A; Gamallo, C; Gonzáles-Garrigues, M; López-Barcons, L; Lozano, E; Navarro, P; Quintanilla, M; Rodrigo, I | 1 |
Chen, J; Levine, AJ; Lin, J; Wu, X | 1 |
Bassa, P; Hicks, K; Inoue, T; Kim, EE; Korkmaz, M; Podoloff, DA; Tansey, W; Wong, FC; Wong, WH; Yang, DJ | 1 |
Kubota, K | 1 |
Carrera, CJ; Carson, DA; Hori, H; Hori, Y; Nobori, T; Rosenbach, MD; Tran, P | 1 |
Favre, G; Hamilton, AD; Miquel, K; Pradines, A; Qian, Y; Sebti, SM; Sun, J | 1 |
Hamilton, AD; Qian, Y; Sebti, SM; Sun, J | 1 |
Björnsson, EH; Gustafsson, GR; Lamberg, K; Långström, B; Nettelbladt, OS; Sundin, AE; Valind, SO | 1 |
Breton, C; Meyn, RE; Story, MD | 1 |
Kubota, T | 1 |
Crist, KA; Hamilton, AD; Lantry, LE; Lubet, RA; Ohkanda, J; Sebti, SM; Wang, Y; Yao, R; You, M; Zhang, Z | 1 |
Hubner, KF | 1 |
Aoyagi, H; Fujisawa, T; Murata, H; Sasaki, Y; Suzuki, K; Tamura, K; Tsujii, H; Yamamoto, N; Yasukawa, T; Yoshikawa, K | 1 |
Dutrillaux, B; Gonçalves, RA; Miccoli, L; Poirson-Bichat, F; Poupon, MF | 1 |
Beinert, T; Binder, D; Fleischhacker, M; Mergenthaler, HG; Oehm, C; Possinger, K; Priem, F; Schmid, P; Schweigert, M; Siebert, G; Stuschke, M; Ziemer, S | 1 |
Harumi, K; Izumo, K; Katagiri, T; Michihata, T; Okazaki, O; Watanabe, T | 1 |
Crist, KA; Hara, M; Lantry, LE; Lubet, RA; Wang, Y; You, M; Zeeck, A; Zhang, Z | 1 |
de Vries, EG; Jager, PL; Langen, KJ; Piers, DA; Pruim, J; Vaalburg, W | 1 |
Da Glória Da Costa Carvalho, M; Machado Paschoal, ME | 1 |
Chen, T; Hayashi, K; Ichiya, Y; Kaneko, K; Koga, H; Kuwabara, Y; Masuda, K; Nakagawa, M; Sasaki, M; Yoshida, T | 1 |
Fateeva, MN; Zherbin, EA | 1 |
Leopold, WR; Miller, EC; Miller, JA | 1 |
Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y | 1 |
Ido, T; Ishiwata, K; Ito, M; Kubota, K; Yamada, S | 1 |
Arai, T; Hara, T; Inagaki, K; Miyazawa, H; Morita, T; Yano, M | 1 |
Ido, T; Ishiwata, K; Itoh, J; Iwata, R; Kameyama, M; Tada, M; Takahashi, T; Tomura, M | 1 |
Fujiwara, Y; Oshita, F; Saijo, N | 1 |
Endo, M; Goseki, N | 1 |
Antoine, E; Breillout, F; Poupon, MF | 1 |
Clark, JC; Fink, I; Hull, WM; O'Reilly, MA; Pryhuber, GS; Whitsett, JA | 1 |
Fujiwara, T; Hatazawa, J; Ido, T; Ishiwata, K; Ito, M; Iwata, R; Kubota, K; Matsuzawa, T | 1 |
Endo, M; Goseki, N; Kosaki, G; Onodera, T | 1 |
Abe, Y; Fujiwara, T; Fukuda, H; Hatazawa, J; Ito, K; Itoh, M; Kubota, K; Matsuzawa, T; Yamaguchi, K; Yoshioka, S | 1 |
Clark, JC; Gazdar, AF; Hull, WM; O'Reilly, MA; Pilot-Matias, TJ; Wert, SE; Whitsett, JA | 1 |
Dillon, ML; Ryo, UY; Shih, WJ | 1 |
Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Kameyama, M; Kubota, K; Matsuzawa, T; Takahashi, T | 1 |
Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Kameyama, M; Kubota, K; Matsuzawa, T; Seo, S; Watanuki, S; Yoshimoto, T | 1 |
Moran, PL; Seligman, PA; Vostrejs, M | 1 |
Abe, Y; Fujiwara, T; Fukuda, H; Itoh, M; Kawai, H; Kubota, K; Matsuzawa, T; Miyazawa, H; Yamaguchi, K; Yamaguchi, T | 1 |
Nakamura, Y; Sakiyama, S; Takenaga, K | 1 |
Hoover, KL; Poirier, LA; Shivapurkar, N | 1 |
Critchley, M; Stretton, TB; Testa, HJ | 1 |
Lombardini, JB; Talalay, P | 1 |
Hundeshagen, H | 1 |
Jovanovic, D | 1 |
7 review(s) available for methionine and Cancer of Lung
Article | Year |
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Alternative and New Radiopharmaceutical Agents for Lung Cancer.
Topics: Acetates; Carbon Radioisotopes; Dideoxynucleosides; Fluorodeoxyglucose F18; Gallium Isotopes; Gallium Radioisotopes; Humans; Lung Neoplasms; Methionine; Misonidazole; Neoplasm Staging; Neuroendocrine Tumors; Peptides; Peptides, Cyclic; Positron Emission Tomography Computed Tomography; Quinolines; Radiopharmaceuticals; Sensitivity and Specificity | 2020 |
Resistance to epidermal growth factor receptor tyrosine kinase inhibitors, T790M, and clinical trials.
Topics: Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Codon, Nonsense; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Methionine; Molecular Targeted Therapy; Protein Kinase Inhibitors; Research Design; Threonine | 2018 |
Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients.
Topics: Adenosylmethionine Decarboxylase; Aged; Carcinoma, Non-Small-Cell Lung; Core Binding Factor Alpha 3 Subunit; Female; Genome-Wide Association Study; Humans; Lung Neoplasms; Male; Methionine; Methionine Sulfoxide Reductases; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Proportional Hazards Models; Quantitative Trait Loci; RNA, Messenger; ROC Curve; Survival Rate | 2019 |
Role of epidermal growth factor receptor mutations in predicting sensitivity or resistance to targeted agents in non-small-cell lung cancer.
Topics: Amino Acid Substitution; Antineoplastic Agents; Asian People; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Quinazolines; Sex Factors; Threonine | 2005 |
[Diagnosis of early cancer with positron emission tomography].
Topics: Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Mediastinal Neoplasms; Methionine; Tomography, Emission-Computed | 1996 |
[Theoretical basis for low-dose CDDP/5-FU therapy].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Lung Neoplasms; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Stomach Neoplasms | 1999 |
Radiolabeled amino acids: basic aspects and clinical applications in oncology.
Topics: Amino Acids; Brain Neoplasms; Breast Neoplasms; Carbon Radioisotopes; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Lymphoma; Methionine; Methyltyrosines; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Tyrosine | 2001 |
2 trial(s) available for methionine and Cancer of Lung
Article | Year |
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In-vivo imaging of methionine metabolism in patients with suspected malignant pleural mesothelioma.
Topics: Adult; Aged; Aged, 80 and over; Carbon Radioisotopes; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Methionine; Middle Aged; Positron Emission Tomography Computed Tomography | 2019 |
18F-FDG and 11C-methionine PET for evaluation of treatment response of lung cancer after stereotactic radiotherapy.
Topics: Aged; Aged, 80 and over; Female; Fluorodeoxyglucose F18; Humans; Image Enhancement; Lung Neoplasms; Male; Methionine; Middle Aged; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiosurgery; Reproducibility of Results; Sensitivity and Specificity; Solitary Pulmonary Nodule; Treatment Outcome | 2004 |
95 other study(ies) available for methionine and Cancer of Lung
Article | Year |
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Quantitative proteomic analysis of the effects of dietary deprivation of methionine and cystine on A549 xenograft and A549 xenograft-bearing mouse.
Topics: Animals; Cystine; Epithelial-Mesenchymal Transition; Heterografts; Lung Neoplasms; Methionine; Mice; Proteomics | 2021 |
Adenoid cystic carcinoma of the parotid gland: a first case report on
Topics: Carcinoma, Adenoid Cystic; Humans; Lung Neoplasms; Methionine; Parotid Gland; Positron Emission Tomography Computed Tomography | 2022 |
Metabolomics and integrated network pharmacology analysis reveal that ginkgolides act as potential active anticancer components by regulating one-carbon metabolism.
Topics: Carbon; Carcinoma, Non-Small-Cell Lung; Chromatography, Liquid; Ginkgo biloba; Ginkgolides; Glutathione; Humans; Lung Neoplasms; Metabolomics; Methionine; Network Pharmacology; Purines; Tandem Mass Spectrometry; Tetrahydrofolates | 2022 |
Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells.
Topics: DNA; Epithelial Cells; Glutathione; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Neoplasms; Methionine; Transcriptome; Vorinostat | 2023 |
A novel methionine metabolism-related signature predicts prognosis and immunotherapy response in lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Humans; Immunotherapy; Lung Neoplasms; Methionine; Prognosis; Racemethionine; Tumor Microenvironment | 2023 |
Methionine-producing tumor micro(be) environment fuels growth of solid tumors.
Topics: Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Proliferation; Escherichia coli; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mammals; Methionine; Racemethionine; S-Adenosylmethionine; Tumor Microenvironment | 2023 |
Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells.
Topics: Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Fibroblasts; Histones; Humans; Lung Neoplasms; Methionine; Methylation; Recombinant Proteins | 2020 |
Reversion from Methionine Addiction to Methionine Independence Results in Loss of Tumorigenic Potential of Highly-malignant Lung-cancer Cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; Methionine; Mice, Nude; Signal Transduction; Tumor Burden | 2021 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
STK11/LKB1 Loss of Function Is Associated with Global DNA Hypomethylation and
Topics: Adenocarcinoma; AMP-Activated Protein Kinase Kinases; Cell Line; Cell Survival; Cluster Analysis; Computational Biology; CpG Islands; Databases, Genetic; DNA Methylation; Epigenesis, Genetic; Genes, ras; Humans; Lung Neoplasms; Methionine; Mutation; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins p21(ras); Repetitive Sequences, Nucleic Acid; S-Adenosylmethionine | 2021 |
Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3).
Topics: Adult; Aged; Aged, 80 and over; Asia; Australia; Case-Control Studies; Cotinine; Europe; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Methionine; Middle Aged; Prospective Studies; Protective Factors; Risk Factors; Sex Factors; Smoking; United States; Vitamin B 6 | 2018 |
Bronchial Mucosa-Associated Lymphoid Tissue Lymphoma Staged by 11C-Methionine.
Topics: Carbon Radioisotopes; Humans; Lung Neoplasms; Lymph Nodes; Lymphoma, B-Cell, Marginal Zone; Male; Methionine; Middle Aged; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals | 2018 |
[Search for the T790M mutation: The need to persevere].
Topics: Aged; Amino Acid Substitution; Biopsy; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Threonine; Time Factors | 2018 |
Epidermal growth factor receptor T790M mutations in non-small cell lung cancer (NSCLC) of Yunnan in southwestern China.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; China; Circulating Tumor DNA; Cohort Studies; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Threonine | 2018 |
Methionine is a metabolic dependency of tumor-initiating cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Line, Tumor; Female; Gene Knockdown Techniques; Glycine Dehydrogenase (Decarboxylating); Humans; Lung Neoplasms; Male; Metabolic Networks and Pathways; Metabolomics; Methionine; Methionine Adenosyltransferase; Mice; Neoplastic Stem Cells; S-Adenosylmethionine | 2019 |
A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk.
Topics: Biomarkers; Folic Acid; Humans; Lung Neoplasms; Male; Methionine; Models, Statistical; Population Surveillance; Prospective Studies; Risk Factors; Vitamin B Complex | 2013 |
Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Farnesyltranstransferase; Female; Humans; Lung Neoplasms; Melanoma; Methionine; p21-Activated Kinases | 2013 |
Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Neoplasm Staging; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Republic of Korea; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Treatment Outcome; Tumor Cells, Cultured | 2014 |
Presence of the minor EGFR T790M mutation is associated with drug-sensitive EGFR mutations in lung adenocarcinoma patients.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Sequence Deletion; Threonine | 2014 |
Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells.
Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Methionine; Mice; Mutation; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Threonine | 2014 |
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation.
Topics: Amino Acid Substitution; Aminopyridines; Carcinoma, Non-Small-Cell Lung; Crystallography, X-Ray; Drug Resistance, Neoplasm; ErbB Receptors; High-Throughput Screening Assays; Humans; Lung Neoplasms; Methionine; Mutation; Protein Kinase Inhibitors; Threonine | 2014 |
Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation.
Topics: Animals; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression; Humans; Isoquinolines; Lung Neoplasms; Membrane Glycoproteins; Membrane Proteins; Methionine; Mice; Models, Biological; Models, Molecular; Molecular Conformation; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Protein Binding; Protein Kinase Inhibitors; Proteolysis; Quinazolines; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2016 |
Newly synthesized podophyllotoxin derivative, LJ12, induces apoptosis and mitotic catastrophe in non-small cell lung cancer cells in vitro.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methionine; Microtubules; Mitosis; Neoplasm Proteins; Podophyllotoxin | 2016 |
The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer.
Topics: Adult; Aged; Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation, Missense; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Threonine; Up-Regulation; Young Adult | 2016 |
Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis.
Topics: Biogenic Polyamines; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Fourier Analysis; Head and Neck Neoplasms; Histamine; Humans; Lung Neoplasms; Male; Methionine; Neoplasms; Nicotinic Acids; Nucleosides; Purines; Pyridinium Compounds; Rectal Neoplasms; Ribose; Spectrometry, Mass, Electrospray Ionization | 2008 |
The feasibility of 11C-methionine-PET in diagnosis of solitary lung nodules/masses when compared with 18F-FDG-PET.
Topics: Adult; Aged; Aged, 80 and over; Feasibility Studies; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Solitary Pulmonary Nodule | 2008 |
Target definition by C11-methionine-PET for the radiotherapy of brain metastases.
Topics: Aged; Aged, 80 and over; Brain Neoplasms; Breast Neoplasms; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Female; Gadolinium; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Positron-Emission Tomography; Sensitivity and Specificity; Tumor Burden | 2009 |
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors | 2010 |
Serum B vitamin levels and risk of lung cancer.
Topics: Adult; Aged; Cohort Studies; Europe; Female; Humans; Incidence; Lung Neoplasms; Male; Methionine; Middle Aged; Odds Ratio; Risk; Vitamin B 6; Vitamin B Complex | 2010 |
Combining an FPTase inhibitor with cisplatin facilitates induction of apoptosis in human A549 lung cancer cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Proliferation; Cisplatin; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Immunoblotting; Lung Neoplasms; Methionine; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2011 |
Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment.
Topics: Animals; Antineoplastic Agents; Breath Tests; Cell Proliferation; Chromatography, Gas; Colonic Neoplasms; Diffusion; Drug Evaluation, Preclinical; Female; Flatulence; Gases; Glucose; Humans; Hyaluronic Acid; Hydrogen Sulfide; Lung Neoplasms; Maillard Reaction; Methionine; Mice; Mice, Nude; Neoplasm Transplantation; Sulfhydryl Compounds; Sulfur Compounds; Transplantation, Heterologous; X-Ray Absorption Spectroscopy | 2012 |
Dietary intake of B vitamins and methionine and risk of lung cancer.
Topics: Adult; Australia; Carbon; Cohort Studies; Diet; Diet Surveys; DNA; Energy Intake; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Proportional Hazards Models; Riboflavin; Risk Factors; Smoking; Surveys and Questionnaires; Vitamin B Complex | 2012 |
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Methionine; Mice; Mice, Nude; Mice, SCID; Molecular Conformation; Mutation; Neoplasm Transplantation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Threonine; Transplantation, Heterologous | 2012 |
Pharmacokinetics, immunogenicity and anticancer efficiency of Aspergillus flavipes L-methioninase.
Topics: Animals; Antineoplastic Agents; Aspergillus; Carbon-Sulfur Lyases; Cell Line, Tumor; Colonic Neoplasms; Half-Life; Humans; Lung Neoplasms; Male; MCF-7 Cells; Methionine; Prostatic Neoplasms; Rabbits | 2012 |
Dietary B vitamin and methionine intakes and lung cancer risk among female never smokers in China.
Topics: China; Cohort Studies; Female; Humans; Incidence; Lung Neoplasms; Methionine; Middle Aged; Prospective Studies; Registries; Risk Factors; Smoking; Surveys and Questionnaires; Vitamin B Complex | 2012 |
Identification of a novel glucocorticoid receptor mutation in budesonide-resistant human bronchial epithelial cells.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding Sites; Bronchi; Budesonide; Carcinoma, Bronchogenic; Cell Line; Cell Line, Tumor; Drug Resistance; Ganciclovir; Glutathione Transferase; Humans; Lung Neoplasms; Methionine; Molecular Sequence Data; Mucous Membrane; Mutation, Missense; Receptors, Glucocorticoid; Recombinant Fusion Proteins; Respiratory Mucosa; Transfection; Valine | 2003 |
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Anticarcinogenic Agents; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Inhibitors; Farnesyltranstransferase; Gene Deletion; Genes, Dominant; Genes, p53; Heterozygote; Imidazoles; Lung Neoplasms; Methionine; Mice; Mice, Inbred A; Mice, Knockout; Mice, Transgenic | 2003 |
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.
Topics: Amino Acids, Sulfur; Carcinoma; Cell Line, Tumor; Cell Survival; Cystathionine; Cysteine; DNA; Glutathione; Humans; Lung Neoplasms; Methionine; Nicotiana; S-Adenosylhomocysteine; S-Adenosylmethionine; Smoke; Time Factors | 2004 |
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Pedigree; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Threonine | 2005 |
Re: Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
Topics: ErbB Receptors; Gene Deletion; Humans; Lung Neoplasms; Methionine; Mutation; Threonine | 2006 |
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
Topics: Amino Acid Substitution; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Threonine | 2006 |
Comparison of MET-PET and FDG-PET for differentiation between benign lesions and lung cancer in pneumoconiosis.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Pneumoconiosis; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Cancer diagnosis with positron computed tomography and carbon-11-labelled L-methionine.
Topics: Aged; Carbon Radioisotopes; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Male; Methionine; Tomography, Emission-Computed | 1983 |
Rates of incorporation of radioactive molecules during the cell cycle.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; In Vitro Techniques; Interphase; Lung Neoplasms; Lymphoma; Methionine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleic Acid Precursors; Sarcoma, Experimental; Sulfur Radioisotopes; Thymidine; Tritium | 1981 |
Carbon-11-methionine PET imaging of malignant melanoma.
Topics: Adult; Aged; Aged, 80 and over; Ear Neoplasms; Ear, External; Feasibility Studies; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Melanoma; Methionine; Middle Aged; Nasal Cavity; Nose Neoplasms; Skin Neoplasms; Tomography, Emission-Computed | 1995 |
Inter-relationships between single carbon units' metabolism and resting energy expenditure in weight-losing patients with small cell lung cancer. Effects of methionine supply and chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Basal Metabolism; Cachexia; Carbon; Carcinoma, Small Cell; Female; Formiminoglutamic Acid; Humans; Lung Neoplasms; Male; Methionine; Middle Aged | 1994 |
[A useful method to evaluate 11C-methionine uptake using positron emission tomography: determination of the optimal scanning time for evaluation and a comparison between the tumor-to-muscle ratio and the distribution absorption ratio].
Topics: Absorption; Bone and Bones; Carbon Radioisotopes; Humans; Lung; Lung Neoplasms; Mediastinal Neoplasms; Methionine; Tomography, Emission-Computed | 1994 |
Expression of heme oxygenase in arsenic-resistant human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Arsenites; Base Sequence; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Gene Expression; Heme Oxygenase (Decyclizing); Humans; Lung Neoplasms; Metalloporphyrins; Methionine; Molecular Sequence Data; Oligodeoxyribonucleotides; Protoporphyrins; RNA, Messenger; Sodium Compounds; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
PET imaging of non-small-cell lung carcinoma with carbon-11-methionine: relationship between radioactivity uptake and flow-cytometric parameters.
Topics: Aged; Aged, 80 and over; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Ploidies; Tomography, Emission-Computed | 1993 |
Evaluation of the treatment response of lung cancer with positron emission tomography and L-[methyl-11C]methionine: a preliminary study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Tomography, Emission-Computed; Tomography, X-Ray Computed; Treatment Outcome | 1993 |
Carbon-11-methionine and PET in evaluation of treatment response of breast cancer.
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Carbon Radioisotopes; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Methionine; Middle Aged; Soft Tissue Neoplasms; Tomography, Emission-Computed | 1993 |
Binding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Cell Line; Epithelium; Glutathione Transferase; Humans; Lung Neoplasms; Macromolecular Substances; Methionine; Molecular Sequence Data; Neoplasm Proteins; Phosphoproteins; Proline; Radioimmunoprecipitation Assay; Rats; Recombinant Fusion Proteins; Sodium Channels; src Homology Domains; Substrate Specificity; Sulfur Radioisotopes; Tumor Cells, Cultured | 1995 |
Suppression of the metastatic phenotype of a mouse skin carcinoma cell line independent of E-cadherin expression and correlated with reduced Ha-ras oncogene products.
Topics: Animals; Blotting, Northern; Cadherins; Cell Line; Chemotaxis; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Expression; Genes, ras; Harvey murine sarcoma virus; Immunohistochemistry; Intermediate Filament Proteins; Lung Neoplasms; Methionine; Mice; Mice, Nude; Neoplasm Metastasis; Phenotype; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; RNA, Messenger; Skin Neoplasms; Transfection; Tumor Cells, Cultured | 1996 |
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein.
Topics: 3T3 Cells; Animals; Apoptosis; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line; G1 Phase; Gene Expression; Humans; Lung Neoplasms; Methionine; Mice; Mutagenesis, Site-Directed; Nuclear Proteins; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Comparison of fluorine-18-fluorodeoxyglucose and carbon-11-methionine PET in detection of malignant tumors.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Sensitivity and Specificity; Soft Tissue Neoplasms; Tomography, Emission-Computed | 1996 |
Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.
Topics: Alanine; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Feasibility Studies; Genetic Vectors; Humans; Lung Neoplasms; Methionine; Methotrexate; Neoplasm Proteins; Purine-Nucleoside Phosphorylase; Purines; Tetrahydrofolates; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
GGTI-298 induces G0-G1 block and apoptosis whereas FTI-277 causes G2-M enrichment in A549 cells.
Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Apoptosis; Benzamides; Cell Division; Enzyme Inhibitors; G1 Phase; G2 Phase; Humans; Lung Neoplasms; Methionine; Mitosis; Resting Phase, Cell Cycle; Transferases; Tumor Cells, Cultured | 1997 |
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.
Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Benzamides; Cell Division; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Lung Neoplasms; Methionine; Mice; Mice, Nude; Neoplasm Transplantation; Oncogene Protein p21(ras); Protein Prenylation; Signal Transduction | 1998 |
Combined fluorine-18-FDG and carbon-11-methionine PET for diagnosis of tumors in lung and mediastinum.
Topics: Aged; Carbon Radioisotopes; Female; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Mediastinal Neoplasms; Methionine; Middle Aged; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1998 |
Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Cell Survival; Culture Media; Cystine; Etoposide; Gene Expression; Genes, bcl-2; Humans; Lung Neoplasms; Methionine; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1998 |
Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Adenoma; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Carcinogens; Enzyme Inhibitors; Genes, ras; Lung Neoplasms; Methionine; Mice; Mutation; Nitrosamines | 2000 |
Can 11C-methionine play a role in lung cancer staging?
Topics: Carbon Radioisotopes; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Methionine; Neoplasm Staging; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed; Tomography, X-Ray Computed | 2000 |
Usefulness of PET with 11C-methionine for the detection of hilar and mediastinal lymph node metastasis in lung cancer.
Topics: Carbon Radioisotopes; Female; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Methionine; Middle Aged; Predictive Value of Tests; Radiopharmaceuticals; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Tomography, Emission-Computed; Tomography, X-Ray Computed | 2000 |
Methionine depletion enhances the antitumoral efficacy of cytotoxic agents in drug-resistant human tumor xenografts.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Brain Neoplasms; Carcinoma, Small Cell; Cell Division; Colonic Neoplasms; Dietary Supplements; Drug Resistance, Multiple; Ethionine; Female; Genes, MDR; Glioma; Glutathione; Homocysteine; Humans; Lung Neoplasms; Male; Methionine; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasms; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Further evidence for oxidant-induced vascular endothelial growth factor up-regulation in the bronchoalveolar lavage fluid of lung cancer patients undergoing radio-chemotherapy.
Topics: Adult; Aged; Bronchoalveolar Lavage Fluid; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Endothelial Growth Factors; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphokines; Male; Methionine; Middle Aged; Oxidation-Reduction; Oxidative Stress; Radiotherapy, Adjuvant; Reactive Oxygen Species; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Brady-tachycardia syndrome after radiotherapy for lung cancer. Assessment by computed tomography and carbon-11 methionine positron emission tomography.
Topics: Aged; Bradycardia; Carbon Radioisotopes; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Male; Methionine; Radiotherapy; Sinoatrial Node; Tachycardia; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1999 |
Chemopreventive efficacy of promising farnesyltransferase inhibitors.
Topics: 3T3 Cells; Adenoma; Alkyl and Aryl Transferases; Animals; Apoptosis; Chemoprevention; Dehydroepiandrosterone; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyltranstransferase; Fluorescent Antibody Technique, Indirect; Gliotoxin; In Situ Nick-End Labeling; Lung Neoplasms; Methionine; Mice; Mice, Inbred A; Mice, Inbred C3H; Monoterpenes; Polyenes; Polymerase Chain Reaction; Polyunsaturated Alkamides; Proliferating Cell Nuclear Antigen; Terpenes | 2000 |
Alteration of A549 carcinoma cell protein synthesis profile induced by lung cancer patient serum.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Large Cell; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Movement; Densitometry; Electrophoresis, Polyacrylamide Gel; Humans; Lung Neoplasms; Methionine; Middle Aged; Neoplasm Proteins; Sulfur Radioisotopes; Tumor Cells, Cultured | 2001 |
Comparison of MET-PET and FDG-PET for differentiation between benign lesions and malignant tumors of the lung.
Topics: Adult; Aged; Diagnosis, Differential; False Negative Reactions; Fluorodeoxyglucose F18; Humans; Lung Diseases; Lung Neoplasms; Methionine; Middle Aged; Radiopharmaceuticals; Retrospective Studies; Tomography, Emission-Computed | 2001 |
[Achievements and perspectives of radioisotope diagnosis of malignant tumors (according to materials in the "Journal of Nuclear Medicine", 1974)].
Topics: Actinoid Series Elements; Animals; Antigens, Neoplasm; Bleomycin; Breast Neoplasms; Female; Gallium Radioisotopes; Humans; Indium; Iodine Radioisotopes; Isotope Labeling; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Metals, Rare Earth; Methionine; Mice; Neoplasms; Radioisotopes; Radionuclide Imaging; Selenium; Technetium; Ytterbium | 1976 |
S--vinyl homocysteine, an analog of ethionine that is highly mutagenic for S. typhimurium TA100.
Topics: Adenoma; Animals; Carcinogens; Ethionine; Female; Lung Neoplasms; Methionine; Mice; Mutagens; Neoplasms, Experimental; Salmonella typhimurium; Structure-Activity Relationship | 1979 |
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms | 1975 |
Positron emission tomography for treatment evaluation and recurrence detection compared with CT in long-term follow-up cases of lung cancer.
Topics: Aged; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Pancoast Syndrome; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1992 |
[Detection of mediastinal lymph node metastasis from lung cancer with positron emission tomography (PET) using 11C-methionine].
Topics: Adult; Aged; Aged, 80 and over; Animals; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Mediastinum; Methionine; Middle Aged; Tomography, Emission-Computed | 1992 |
Tumor diagnosis by PET: potential of seven tracers examined in five experimental tumors including an artificial metastasis model.
Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Disease Models, Animal; Floxuridine; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fucose; Lung Neoplasms; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymidine; Tomography, Emission-Computed; Tritium | 1992 |
Radiation sensitivities in various anticancer-drug-resistant human lung cancer cell lines and mechanism of radiation cross-resistance in a cisplatin-resistant cell line.
Topics: Antineoplastic Agents; Cell Line; Cisplatin; DNA Damage; DNA Repair; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Methionine; Radiation Tolerance; Tumor Cells, Cultured | 1992 |
Thiol depletion and chemosensitization on nimustine hydrochloride by methionine-depleting total parenteral nutrition.
Topics: Amino Acids; Animals; Blood Cell Count; Body Weight; Liver; Lung Neoplasms; Male; Methionine; Neoplasms, Experimental; Nimustine; Nutritional Status; Organ Size; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1990 |
Methionine dependency of malignant tumors: a possible approach for therapy.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Movement; Colonic Neoplasms; Culture Media; Female; Homocysteine; Humans; Lung Neoplasms; Methionine; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Tumor Cells, Cultured | 1990 |
Phorbol ester inhibits surfactant protein SP-A and SP-B expression.
Topics: Adenocarcinoma; Cell Line; Dactinomycin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Kinetics; L-Lactate Dehydrogenase; Lung Neoplasms; Methionine; Phorbol 12,13-Dibutyrate; Protein Binding; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Differential diagnosis of lung tumor with positron emission tomography: a prospective study.
Topics: Adult; Aged; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Prospective Studies; Tomography, Emission-Computed | 1990 |
Influence of L-methionine-deprived total parenteral nutrition on the tumor tissue and plasma amino acids fraction and the host metabolism: experimental study with Sato lung carcinoma-bearing rats.
Topics: Amino Acids; Animals; Body Weight; Carcinoma; Glucose; Lung Neoplasms; Male; Methionine; Neoplasm Transplantation; Neoplasms, Experimental; Parenteral Nutrition, Total; Rats | 1989 |
Relationship between histologic type of primary lung cancer and carbon-11-L-methionine uptake with positron emission tomography.
Topics: Adenocarcinoma; Carbon Radioisotopes; Carcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Methionine; Tomography, Emission-Computed | 1989 |
Glucocorticoids regulate surfactant protein synthesis in a pulmonary adenocarcinoma cell line.
Topics: Adenocarcinoma; Cell Line; Dexamethasone; DNA, Neoplasm; Humans; Lung Neoplasms; Methionine; Microscopy, Electron; Pulmonary Surfactants; RNA, Messenger; Sulfur Radioisotopes; Tumor Cells, Cultured | 1989 |
Carbon-11-L-methionine uptake with PET as a predictor of prognosis for bronchogenic carcinoma patients.
Topics: Carbon Radioisotopes; Carcinoma, Bronchogenic; Humans; Lung Neoplasms; Methionine; Prognosis; Radionuclide Imaging | 1989 |
Metabolic fate of L-[methyl-11C]methionine in human plasma.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Humans; Lung Neoplasms; Methionine; Middle Aged; Tomography, Emission-Computed | 1989 |
Quantitative evaluation of L-[methyl-C-11] methionine uptake in tumor using positron emission tomography.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Female; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Time Factors; Tomography, Emission-Computed | 1989 |
Transferrin synthesis by small cell lung cancer cells acts as an autocrine regulator of cellular proliferation.
Topics: Carcinoma, Small Cell; Carrier Proteins; Cell Cycle; Cell Division; Cell Line; Chromatography, Gel; Culture Media; Growth Substances; Humans; Iron; Iron-Binding Proteins; Leukemia, Myeloid, Acute; Lung Neoplasms; Methionine; Receptors, Transferrin; Transferrin; Transferrin-Binding Proteins; Tumor Cells, Cultured | 1988 |
Lung tumor imaging by positron emission tomography using C-11 L-methionine.
Topics: Carbon Radioisotopes; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Diagnosis, Differential; Humans; Lung Neoplasms; Methionine; Silicosis; Tomography, Emission-Computed; Tuberculoma | 1985 |
[Positron emission tomography of lung cancer using 18F-2-fluoro-2-deoxy-D-glucose and L-[11C-methyl]-methionine].
Topics: Aged; Carbon Radioisotopes; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Deoxy Sugars; Deoxyglucose; Fluorine; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Radioisotopes; Radionuclide Imaging | 1987 |
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Lung Neoplasms; Methionine; Mice; Neoplasm Metastasis; Tropomyosin | 1988 |
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Male; Methionine; Phenobarbital; Prohibitins; Rats; Rats, Inbred F344; Weaning | 1986 |
Combined use of 99mtechnetium-labelled macroaggregates of albumin and 75selenium-selenomethionine in the diagnosis of lung cancer.
Topics: Adenocarcinoma; Bronchiectasis; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Empyema; Hamartoma; Humans; Injections, Intravenous; Lung; Lung Neoplasms; Methionine; Neoplasm Metastasis; Pneumonia; Radiography; Radionuclide Imaging; Selenium; Serum Albumin; Spectrometry, Gamma; Technetium; Thymoma; Thymus Neoplasms; Tuberculosis, Pulmonary | 1974 |
Effect of inhibitors of adenosine triphosphate: L-methionine S-adenosyltransferase on levels of S-adenosyl-L-methionine and L-methionine in normal and malignant mammalian tissues.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Caproates; Carbon Isotopes; Carcinoma 256, Walker; Female; Leucine; Leukemia L1210; Lung Neoplasms; Male; Melanoma; Methionine; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; S-Adenosylmethionine; Time Factors; Transferases; Tritium | 1973 |
[Quantitative studies on organ distribution following administration of various radioisotopes, using a 10-crystal scanner and computer scintigraphy].
Topics: Coloring Agents; Computers; Gold Colloid, Radioactive; Gold Isotopes; Humans; Iodine Radioisotopes; Kidney; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Methods; Neoplasm Metastasis; Pancreas; Radioisotopes; Radionuclide Imaging; Selenium | 1968 |
75Se-selenomethionine uptake by malignant tumours.
Topics: Blood Specimen Collection; Bone Neoplasms; Carcinoma; Hodgkin Disease; Humans; Injections, Intravenous; Lung Neoplasms; Lymphoma, Non-Hodgkin; Methionine; Myosarcoma; Neoplasms; Radioisotopes; Radiometry; Radionuclide Imaging; Rhabdomyosarcoma; Selenium; Temporal Bone | 1968 |