methionine has been researched along with Cancer of Liver in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (57.95) | 18.7374 |
| 1990's | 32 (16.41) | 18.2507 |
| 2000's | 18 (9.23) | 29.6817 |
| 2010's | 19 (9.74) | 24.3611 |
| 2020's | 13 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, D; Piao, H; Wang, W | 1 |
| Agopian, V; Ayoub, W; Benhammou, JN; Choi, G; Dong, TS; Durazo, F; Elashoff, D; Enayati, P; Fiehn, O; Goodman, MT; Hussain, SK; Jacobs, JP; Lagishetty, V; Noureddin, M; Pisegna, JR; Sundaram, V | 1 |
| Chen, PM; Chiang, EI; Huang, CC; Hwang, HH; Ko, HA; Li, JR; Liu, CC; Tsai, CH | 1 |
| Fang, AP; He, TT; Liu, XZ; Liu, ZY; Luo, Y; Wusiman, M; Xiao, HW; Yishake, D; Zhu, HL | 1 |
| Guo, H; Hu, R; Huang, L; Kong, X; Qian, Y; Sha, M; Xia, Q; Xu, D; Zhang, X; Zhang, Y | 1 |
| Abe, A; Miyajima, K; Nakae, D; Nakane, S; Suzuki-Kemuriyama, N; Yuki, M | 1 |
| Angulo, S; Carril, E; Godzien, J; Lanzón, B; Rupérez, FJ; Valdecantos, MP; Valverde, ÁM | 1 |
| Antwi, SO; Campbell, PT; Liao, LM; McGlynn, KA; Norez, DA; Patel, T; Petrick, JL; Roberts, LR; Stevens, VL | 1 |
| Deterding, LJ; Gao, X; Ji, M; Kang, K; Li, L; Li, X; Li, Y; Liu, J; Locasale, JW; Shats, I; Tong, L; Tong, X; Williams, JG; Xu, Q | 1 |
| Guo, Z; Jin, C; Li, Y; Shao, J; Su, Y; Wang, S; Wang, X; Zhang, F; Zhang, Z; Zheng, S | 1 |
| Badone, B; Bonanomi, M; Coccetti, P; Gaglio, D; Maffioli, E; Milanesi, R; Nonnis, S; Tedeschi, G; Tripodi, F; Vescovi, M | 1 |
| Buechler, C; Haberl, EM; Höring, M; Krautbauer, S; Liebisch, G; Pohl, R; Rein-Fischboeck, L | 1 |
| Budhu, A; Chaisaingmongkol, J; Chang, CW; Diggs, LP; Forgues, M; Greten, TF; Heinrich, S; Hung, MH; Lee, JS; Ma, C; Ma, L; Ruchirawat, M; Ruppin, E; Wang, XW | 1 |
| Chen, XL; Chen, YM; Lan, QY; Liao, GC; Zhang, YJ; Zhou, RF; Zhou, ZG; Zhu, HL | 1 |
| Channa, IS; Hashim, Z; Ilyas, A; Zarina, S | 1 |
| Columbano, A; Orrù, C; Perra, A; Szydlowska, M; Taguchi, K; Yamamoto, M; Zavattari, P | 1 |
| Corn, DJ; Kuang, Y; Lee, Z; Tian, H; Wang, F | 2 |
| Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM | 1 |
| Hatano, E; Koyama, Y; Nakamura, K; Seo, S; Takemoto, K; Tanabe, K; Taura, K; Toriguchi, K; Uemoto, S | 1 |
| Barghash, A; Bohle, RM; Cadenas, C; Gemperlein, K; Gianmoena, K; Haybaeck, J; Helms, V; Hengstler, JG; Kessler, SM; Kiemer, AK; Lammert, F; Mueller, R; Pokorny, J; Simon, Y; van Rooijen, N; Zimmer, V | 1 |
| Banwat, E; Chetwood, J; Crossey, MM; Dona, AC; Duguru, M; Fye, HK; Garside, DA; Holmes, E; Kasstan, B; Khan, SA; Ladep, NG; Lemoine, M; Lewis, MR; Nicholson, JK; Njai, HF; Njie, R; Okeke, E; Shimakawa, Y; Taal, M; Taylor-Robinson, SD; Thillainayagam, AV; Thursz, MR; Wijeyesekera, A | 1 |
| Egger, M; Eggert, T; ElGindi, M; Felsher, DW; Greten, TF; Han, M; Heikenwalder, M; Jin, P; Kapoor, V; Kesarwala, AH; Kleiner, DE; Luo, J; Ma, C; McVicar, DW; Medina-Echeverz, J; Stroncek, DF; Terabe, M; Thornton, AM; Weber, A; Zhang, H | 1 |
| Buechler, C; Eisinger, K; Haberl, EM; Krautbauer, S; Neumann, M; Pohl, R; Rein-Fischboeck, L; Weiss, TS; Zimny, S | 1 |
| Bagnyukova, TV; Beland, FA; Muskhelishvili, L; Pogribny, IP; Ross, SA; Tryndyak, VP | 1 |
| MILLER, EC; MILLER, JA | 1 |
| Elias, MS; Green, RM; Henkel, AS | 1 |
| Choi, SH; Kim, HY; Kim, JR; Kwak, GH | 1 |
| Funabiki, R; Kawasaki, M; Miura, Y; Yagasaki, K | 1 |
| Bosserhoff, AK; Dettmer, K; Hellerbrand, C; Kirovski, G; Oefner, PJ; Samejima, K; Stevens, AP | 1 |
| Lu, SC; Mato, JM | 2 |
| Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC | 1 |
| Kaneoka, Y; Kumada, T; Maeda, A; Toyoda, H | 1 |
| Beland, FA; James, SJ; Pogribny, IP | 1 |
| Ahn, IY; Bae, JY; Bang, du Y; Han, EY; Jang, DE; Kim, DH; Kim, HS; Kim, KB; Kwack, SJ; Kwak, EH; Kwak, MY; Lee, BM; Lee, J; Lee, YJ; Lim, DS; Lim, SK; Park, KL; Roh, T; Yoo, SD | 1 |
| Alberto, JM; Ayav, A; Bressenot, A; Bronowicki, JP; Chéry, C; Fofou-Caillierez, M; Forges, T; Guéant, JL; Namour, F; Pellanda, H | 1 |
| Avila, MA; García-Trevijano, ER; Latasa, MU; Lu, SC; Martínez-Chantar, ML; Mato, JM; Varela-Rey, M | 1 |
| Choudhury, P; Datta, B; Datta, R; Ghosh, A | 1 |
| Ding, J; Guo, Z; He, C; Lin, J; Lin, L; Tu, C; Wang, X; Wang, Z; Yan, C; You, X; Zhang, J | 1 |
| GIUDICE, G; MAGGIO, R; MUTOLO, V | 1 |
| CHO, YS; MORRIS, HP; PITOT, HC | 1 |
| FARBER, E | 1 |
| KINOSITA, R; MIYAJI, H | 1 |
| BURNS, JJ; CONNEY, AH | 1 |
| DUNN, WL | 1 |
| MANGIANTINI, M | 1 |
| Kramer, PM; Pereira, MA; Tao, L; Wang, W | 1 |
| Avila, MA; Caballería, J; Corrales, FJ; Fernández-Irigoyen, J; Lu, SC; Mato, JM; Muñoz, J; Prieto, J; Riezu, JI; Santamaría, E; Sesma, L | 1 |
| Bierczyńska-Krzysik, A; Bonar, E; Dubin, A; Koj, A; Noga, M; Silberring, J; Stalińska, K | 1 |
| Banerjee, R; Bauman, Z; Braun, A; Lu, SC; Prudova, A; Vitvitsky, V | 1 |
| Bai, S; Datta, J; Ghoshal, K; Huang, Y; Jacob, ST; Li, X; Pogribny, I; Pogribny, M; Young, D | 1 |
| Bai, S; Datta, J; Frankel, W; Ghoshal, K; Jacob, ST; Kutay, H; Motiwala, T; Pogribny, I | 1 |
| Calvisi, DF; De Miglio, MR; De Murtas, V; Feo, F; Frau, M; Ladu, S; Muroni, MR; Pascale, RM; Pellegrino, R; Pinna, F; Simile, MM; Tomasi, ML; Virdis, P | 1 |
| Kanegae, K; Kohanawa, M; Kuge, Y; Seki, K; Takahashi, T; Tamaki, N; Yi, M; Zhao, S; Zhao, Y | 1 |
| BAUMANN, CA; CLAYTON, CC; GRIFFIN, AC | 1 |
| Aransay, AM; Ariz, U; Calvisi, DF; Capdevila, A; Esteller, M; Fraga, M; Lu, SC; Luka, Z; Martínez, N; Martínez-Chantar, ML; Mato, JM; Matthiesen, R; Rodríguez, J; Varela, M; Vázquez-Chantada, M; Wagner, C; Yang, H | 1 |
| Lu, SC; Martínez-Chantar, ML; Mato, JM | 1 |
| Brown, CH; Filson, EJ; Mlecko, LM; Rodríguez-Antúnez, A | 1 |
| Bartalena, L; Robbins, J; Tata, JR | 1 |
| Hirose, S; Nagasue, N; Ogawa, Y; Sasaki, Y; Yukaya, H | 1 |
| Miyazaki, M; Watanabe, A | 1 |
| Baumann, H; Doyle, D; Gelehrter, TD | 1 |
| Higashi, T | 1 |
| Obrist, R; Sandberg, AL | 1 |
| Colman, RW; Glasgow, JE | 1 |
| Farber, E; Ghoshal, AK; Lim, YP; Rushmore, TH | 1 |
| Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Lenhart, G; Morrison, G; Rogers, AE | 1 |
| Potvin, B; Stanley, P; Stockert, RJ; Tao, L; Wolkoff, AW | 1 |
| Endo, M; Goseki, N; Kando, F; Maruyama, M; Nagai, K; Shimoju, K; Wada, Y | 1 |
| Akiyama, S; Gottesman, MM; Pastan, I; Schoenlein, P; Shen, DW | 1 |
| Matsumata, T; Nishizaki, T; Sugimachi, K; Taketomi, A; Yamamoto, K | 1 |
| Ahlström, H; Bergh, J; Jansson, T; Långström, B; Lilja, A; Westlin, JE | 1 |
| Liu, J; Liu, JH; Marumo, F; Miyakawa, H; Mori, K; Sato, C; Takano, T | 1 |
| Bereziat, G; Janvier, B; Loriette, C; Mangeney-Andreani, M; Vandenbrouck, Y | 1 |
| Lo, SJ; Sheu, SY | 1 |
| Poirier, LA | 3 |
| Guo, P; Maloney, B; Nodgreen, R; Scholz, E; Turek, J | 1 |
| Huang, HY; Lu, SC | 1 |
| Bonifácio, MJ; Breakfield, XO; Ezzeddine, D; Sakaki, Y; Saraiva, MJ | 1 |
| McLeod, RS; Selby, SL; Westerlund, J; Yao, Z; Zhao, Y | 1 |
| Beck, SC; Buchman, TG; De Maio, A | 1 |
| Kong, N; Lodish, HF | 1 |
| Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E | 1 |
| Brandsch, R; Otto, A; Sailer, HP; Stoltz, M | 1 |
| Cederbaum, AI; Yang, MX | 1 |
| Henning, SM; Swendseid, ME | 1 |
| Henning, SM; Ivandic, BT; Liao, F; Swendseid, ME | 1 |
| Biller, SA; Chen, Y; Chu, CH; Dickson, JK; Gordon, DA; Gregg, RE; Jamil, H; Wetterau, JR; Yan, M | 1 |
| Chen, WN; Leong, AL; Oon, CJ; Teng, SW; Zhao, Y | 1 |
| Avila, MA; Berasain, C; Caballería, J; Corrales, FJ; Lu, SC; Martín-Duce, A; Mato, JM; Prieto, J; Rodés, J; Torres, L; Yang, H | 1 |
| Hitachi, PM; Takayama, S; Yamada, K | 1 |
| Fateeva, MN; Zherbin, EA | 1 |
| Rogers, AE | 1 |
| Ezirike, J; Kim, S; Morris, HP; Paik, WK | 1 |
| Ishikawa, R; Kusakabe, K; Maki, M; Ono, Y; Yamasaki, T | 1 |
| Hilliard, JK; Sneider, TW | 1 |
| Hurlbert, RB; Liau, MC; Lin, GW | 1 |
| Alexander, JJ; Deinhardt, F; Frösner, GG; Hofschneider, PH; Zaslavsky, V | 1 |
| Freikopf, A; Kulka, RG | 1 |
| Altman, NH; Brada, Z; Bulba, S | 1 |
| Kojima, S; Sakai, K; Yamane, Y | 1 |
| Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y | 1 |
| Swann, PF | 1 |
| Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F | 1 |
| Borén, J; Graham, L; Olofsson, SO; Scott, J; Wettesten, M; White, A | 1 |
| Geuze, HJ; Rijnboutt, S; Stoorvogel, W; Strous, GJ | 1 |
| Burkey, BF; Degen, SJ; Jamison, CS | 1 |
| Laver, GW; McMullen, E; Mehta, R; Stapley, R | 1 |
| Baumann, H; Won, KA | 1 |
| Hiramoto, M; Imaizumi, T; Kawamura, Y; Satoh, K; Takamatsu, M; Takamatsu, S; Yoshida, H | 1 |
| Donadel, G; Frank, R; Gabrielli, F; Garzelli, C | 1 |
| Kanduc, D; Quagliariello, E | 1 |
| Lyn-Cook, B; Poirier, LA; Zapisek, W | 1 |
| Delhaye, M; Galand, P; Mairesse, N | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Olden, K; Yeo, KT; Yeo, TK | 1 |
| Beale, EG; Granner, DK; Leverence, RR | 1 |
| Cooper, AD; Craig, WY; Nutik, R | 1 |
| Hashimoto, S; Morito, F; Saito, H; Suzuki, K | 1 |
| Blau, R; Burk, M; Stoffel, W | 1 |
| Bondjers, G; Borén, J; Boström, K; Carrella, M; Jarfeldt, M; Norfeldt, PI; Olofsson, SO; Wettesten, M; Wiklund, O | 1 |
| Armellino, D; Jaffe, EA; Tollefsen, DM | 1 |
| Olson, JW | 1 |
| Antonelli, A; Bartalena, L; Martino, E; Pacchiarotti, A; Pinchera, A; Robbins, J | 1 |
| Barsigian, C; Base, W; Fish, S; Gilman, P; Martinez, J; Schaeffer, A | 1 |
| Silverman, D; vanderSpek, J; Zannis, VI | 1 |
| Cooper, AD; Ellsworth, JL; Erickson, SK | 1 |
| Newberne, PM | 1 |
| Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ | 1 |
| Hoover, KL; Poirier, LA; Shivapurkar, N | 1 |
| Gottschalk, A; Hoffer, PB | 1 |
| Pitot, HC; Weiss, JW | 2 |
| Morris, HP; Petri, WA; Poirier, LA | 1 |
| Newberne, PM; Rogers, AE; Wogan, GN | 1 |
| Hancock, RL | 2 |
| Donnell, GN; Koch, R; Lieberman, E; Shaw, KN | 1 |
| Busch, H; Nakamura, T; Prestayko, AW | 1 |
| Bilik, E; Sheid, B | 2 |
| Potter, VR; Sneider, TW | 1 |
| Ben-Porath, M; Kaplan, E | 1 |
| Busch, H; Hodnett, JL; Moriyama, Y; Prestayko, AW | 1 |
| Craddock, VM | 2 |
| Kerr, SJ | 1 |
| Wolberg, WH | 1 |
| Flatt, NC; Hurlbert, RB; Liau, MC | 1 |
| Eddleston, AL; Osborn, SB; Pagaltsos, AP; Rake, MO; Williams, R | 1 |
| Sneider, TW | 1 |
| Byvoet, P | 2 |
| Anderson, JE; Perlmutter, GS | 1 |
| Hurlbert, RB; Liau, MC; O'Rourke, CM | 1 |
| Inose, M; Iwanami, Y; Miyata, S | 1 |
| Sneider, T | 1 |
| Agostini, C; Comi, P; Mortara, G | 1 |
| Stolzenberg, J | 1 |
| Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
| Burdine, JA; Calderon, M; Goyal, RK; Grubb, MN; Hersh, T; Kaldenbaugh, H | 1 |
| Bancons, J; Blanquet, P; Dubarry, JJ; Ducassou, D; Leccia, MF; Quinton, A | 1 |
| Pitot, HC; Wilkinson, DS | 1 |
| Davies, ER | 1 |
| Kusakabe, K | 1 |
| Murty, CN; Sidransky, H; Verney, E | 1 |
| Nau, F | 1 |
| Finkelstein, JD; Grossman, MR; Kyle, WE; Morris, HP | 1 |
| Baliga, BS; Borek, E; Nielsen, HR; Nyholm, K; Sjolin, KE; Wong, R | 1 |
| Bouali, AB; Cheguillaume, J; Joubaud, F; Minier, J; Pithon, G | 1 |
| Howard, E; Tidwell, T | 1 |
| Kartenbeck, J; Schreiber, G; Schreiber, M | 1 |
| Johnson, PM; Muroff, LR | 1 |
| Inose, M; Iwanami, Y | 1 |
| Domingo, M; Kaplan, E | 1 |
| Palinkashi, DG | 1 |
| Geddes, EW; Kew, MC; Levin, J | 1 |
| Caroli, J; de Saint-Laurent, J; Hadchouel, P; Milhaud, G | 1 |
| Pegg, AE | 1 |
| Caroli, J; de Saint-Laurent, J; Hadchouel, P; Milhaud, G; Theodoropoulos, G | 1 |
| Farber, E; Hawks, A; Magee, PN; Pegg, AE; Swann, PF | 1 |
| Craddock, VM; Turberville, C | 1 |
| Eddleston, A; Osborne, SB; Pagaltsos, S; Rake, MO; Williams, R | 1 |
| Käser, H; Mönch, E; Stefan, H | 1 |
| Iwig, J; Schmalbach, J; Thiemann, KJ | 1 |
| Ackerman, NB | 1 |
| Schneider, C | 1 |
| Kahle, P; Kessel, H; Kröger, H | 1 |
| Hundeshagen, H | 1 |
| Rutenburg, AM; Smith, EE | 1 |
11 review(s) available for methionine and Cancer of Liver
| Article | Year |
|---|---|
The hepatocarcinogenic effect of methionine and choline deficient diets: an adaptation to the Warburg effect?
Topics: Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Humans; Liver Neoplasms; Methionine | 2011 |
Molecular alterations in hepatocarcinogenesis induced by dietary methyl deficiency.
Topics: Animals; Deficiency Diseases; Diet; DNA Damage; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Lipid Metabolism; Liver Neoplasms; Methionine; MicroRNAs; Oxidative Stress | 2012 |
ETHIONINE CARCINOGENESIS.
Topics: Bacteria; Carcinogenesis; Ethionine; Humans; Liver Neoplasms; Metabolism; Methionine; Neoplasms; Neoplasms, Experimental; Pharmacology; Toxicology | 1963 |
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
Topics: Animals; Cell Death; Central Nervous System Depressants; Ethanol; Female; Hepatocytes; Humans; Isoenzymes; Liver; Liver Diseases, Alcoholic; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine | 2005 |
Methionine metabolism and liver disease.
Topics: Animals; Choline; Choline Deficiency; Folic Acid Deficiency; Humans; Liver Diseases; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation | 2008 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms | 1996 |
Physiological methylation in carcinogenesis.
Topics: Animals; Choline Deficiency; DNA; Humans; Liver Neoplasms; Methionine; Methylation; Oxidation-Reduction; S-Adenosylmethionine | 1990 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Dietary methyl groups and cancer.
Topics: Animals; Choline Deficiency; Diet; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats | 1986 |
Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms | 1974 |
2 trial(s) available for methionine and Cancer of Liver
| Article | Year |
|---|---|
[Clinical evaluation of anticancer effect of methionine-depleting total parenteral nutrition with 5-fluorouracil and/or mitomycin C].
Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Mitomycin; Parenteral Nutrition, Total; Stomach Neoplasms | 1995 |
Positron emission tomography studies in patients with locally advanced and/or metastatic breast cancer: a method for early therapy evaluation?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbon Radioisotopes; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Lymphatic Metastasis; Methionine; Tomography, Emission-Computed | 1995 |
182 other study(ies) available for methionine and Cancer of Liver
| Article | Year |
|---|---|
[Identification of
Topics: Animals; Carcinoma, Hepatocellular; Chromatography, Liquid; Disease Models, Animal; Inflammation; Liver; Liver Neoplasms; Mass Spectrometry; Methionine; Mice | 2021 |
Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis.
Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Microbiota; Proportional Hazards Models; Prospective Studies; Risk Factors; Taurocholic Acid | 2022 |
Downregulation of Methionine Cycle Genes
Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Down-Regulation; Eukaryotic Initiation Factor-3; Gene Expression Regulation, Neoplastic; Glycine N-Methyltransferase; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasm Invasiveness; Peptide Elongation Factor 1; Promoter Regions, Genetic; Protein Biosynthesis; Survival Analysis | 2022 |
Dietary intake of one-carbon metabolism-related nutrients and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort.
Topics: Carbon; Carcinoma, Hepatocellular; Cohort Studies; Diet; Eating; Folic Acid; Humans; Liver Neoplasms; Methionine; Nutrients; Prospective Studies; Risk Factors | 2022 |
A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response.
Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Self Renewal; Chemoembolization, Therapeutic; Cholangiocarcinoma; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase | 2022 |
Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fibrosis; Interleukin-8; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2023 |
Metabolic impact of partial hepatectomy in the non-alcoholic steatohepatitis animal model of methionine-choline deficient diet.
Topics: Animals; Choline; Diet; Disease Models, Animal; Hepatectomy; Lipid Metabolism; Liver; Liver Neoplasms; Male; Metabolomics; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2020 |
One-carbon metabolism-related micronutrients intake and risk for hepatocellular carcinoma: A prospective cohort study.
Topics: Carbon; Carcinoma, Hepatocellular; Diet; Dietary Supplements; Eating; Female; Folic Acid; Humans; Liver Neoplasms; Male; Methionine; Micronutrients; Middle Aged; Nutritional Status; Prospective Studies; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2020 |
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cysteine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 4; Liver; Liver Neoplasms; Mesoderm; Metabolic Networks and Pathways; Metabolome; Methionine; Mice; Sorafenib; Transcription, Genetic | 2020 |
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
Topics: Amino Acid Transport Systems; Animals; Calcium-Binding Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cellular Senescence; Coordination Complexes; Copper; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Telomerase; Transfection; Xenograft Model Antitumor Assays | 2020 |
Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Cell Proliferation; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Mitochondria; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease.
Topics: alpha-Fetoproteins; Animal Feed; Animals; Carcinoma, Hepatocellular; Ceramides; Choline; Choline Deficiency; Diethylnitrosamine; Disease Models, Animal; Humans; Lipidomics; Lipids; Lipogenesis; Liver; Liver Cirrhosis; Liver Neoplasms; Lysophosphatidylcholines; Male; Mass Spectrometry; Methionine; Mice; Mice, Inbred C3H; Non-alcoholic Fatty Liver Disease; Oxidative Stress | 2020 |
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Line, Tumor; CRISPR-Cas Systems; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylmethionine; T-Lymphocytes; Transcriptome | 2021 |
Higher dietary intakes of choline and betaine are associated with a lower risk of primary liver cancer: a case-control study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Case-Control Studies; China; Choline; Diet; Female; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Odds Ratio; Population Surveillance; Risk Assessment; Risk Factors; Young Adult | 2017 |
Alendronate and FTI-277 combination as a possible therapeutic approach for hepatocellular carcinoma: An in vitro study.
Topics: Alendronate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methionine; Proteomics; Signal Transduction; Tandem Mass Spectrometry; Time Factors | 2018 |
Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis.
Topics: Alkylating Agents; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Gene Silencing; Lipotropic Agents; Liver Neoplasms; Methionine; NF-E2-Related Factor 2; Rats; Treatment Outcome | 2018 |
Metabolism of radiolabeled methionine in hepatocellular carcinoma.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cycloheximide; Hepatocytes; Liver Neoplasms; Marmota; Methionine; Protein Biosynthesis; Radionuclide Imaging; Radiopharmaceuticals; Rats; Solubility; Tritium; Water | 2014 |
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; Drug Therapy, Combination; End Stage Liver Disease; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Neoplasms; Liver Transplantation; Male; Methionine; Middle Aged; Mutation; Retrospective Studies; Risk Factors; Secondary Prevention; Sex Factors; Tyrosine | 2014 |
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.
Topics: Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Choline Deficiency; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice, Inbred C57BL; Middle Aged; Molecular Targeted Therapy | 2014 |
In vitro characterization of uptake mechanism of L-[methyl-(3)H]-methionine in hepatocellular carcinoma.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Cell Survival; Liver Neoplasms; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; Radionuclide Imaging; S-Adenosylmethionine; Transfection | 2014 |
Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
Topics: Acetyltransferases; Animals; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Fatty Acid Elongases; Fatty Acids; Humans; Inflammation; Liver Neoplasms; Methionine; Mice; Mice, Inbred DBA; Mice, Obese; Non-alcoholic Fatty Liver Disease; RNA, Messenger | 2014 |
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Choline; Creatine; Female; Humans; Ketoglutaric Acids; Liver Neoplasms; Male; Methionine; Middle Aged; Niacinamide; Phenotype; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Young Adult | 2014 |
NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Case-Control Studies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Choline; Diet; Disease Models, Animal; Genes, myc; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Liver; Liver Neoplasms; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species | 2016 |
Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes.
Topics: Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Choline; Diet, High-Fat; Disease Models, Animal; Hep G2 Cells; Hepatic Stellate Cells; Humans; Liver Neoplasms; Male; Methionine; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; RAW 264.7 Cells; Tubulin; Up-Regulation | 2017 |
Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.
Topics: Animals; Carcinoma, Hepatocellular; Diet; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Methionine; Methylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Random Allocation; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Transforming Growth Factor beta | 2008 |
Correlation of the level of hepatic riboflavin with the appearance of liver tumors in rats fed aminoazo dyes.
Topics: Animals; Carcinogens; Coloring Agents; Diet; Liver Neoplasms; Methionine; Rats; Riboflavin; Vitamin A | 1948 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response | 2009 |
Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide.
Topics: Animals; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Free Radical Scavengers; Humans; Liver Neoplasms; Methionine; Methionine Sulfoxide Reductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Saccharomyces cerevisiae | 2009 |
Comparison of the effects on lipid metabolism of dietary methionine and cystine between hepatoma-bearing and normal rats.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Cystine; Diet; Eating; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipolysis; Liver Neoplasms; Male; Methionine; Rats | 2010 |
Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies.
Topics: Calibration; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, Liquid; Humans; Liver Neoplasms; Methanol; Methionine; Polyamines; Purine-Nucleoside Phosphorylase; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tumor Cells, Cultured | 2010 |
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Amino acid substitutions in the hepatitis C virus core region are associated with postoperative recurrence and survival of patients with HCV genotype 1b-associated hepatocellular carcinoma.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatectomy; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Leucine; Liver; Liver Function Tests; Liver Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Prognosis; RNA, Messenger; Survival Analysis; Viral Core Proteins | 2011 |
Chemopreventive mechanisms of methionine on inhibition of benzo(a)pyrene-DNA adducts formation in human hepatocellular carcinoma HepG2 cells.
Topics: Arginase; Benzo(a)pyrene; Cathepsin B; DNA Adducts; Glutathione Transferase; Guanine Nucleotide Dissociation Inhibitors; Hep G2 Cells; Histamine N-Methyltransferase; Humans; Lactoylglutathione Lyase; Liver Neoplasms; Methionine; Proteomics; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Spermidine Synthase; Superoxide Dismutase | 2012 |
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
Topics: Alternative Splicing; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Creatinine; Humans; Imidazolidines; Liver Neoplasms; Methionine | 2012 |
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine.
Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; RNA, Messenger; S-Adenosylmethionine; Tumor Cells, Cultured | 2003 |
A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.
Topics: Acetylglucosaminidase; Amino Acid Substitution; Aminopeptidases; Animals; Blotting, Western; Carcinoma, Hepatocellular; DNA Primers; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Glutathione Transferase; Glycoproteins; Glycosylation; Green Fluorescent Proteins; Liver Neoplasms; Luminescent Proteins; Methionine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Precipitin Tests; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Threonine; Tumor Cells, Cultured | 2003 |
Monofunctional platinum complexes showing potent cytotoxicity against human liver carcinoma cell line BEL-7402.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Methionine; Organoplatinum Compounds; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
[The activation of methionine for transmethylation in regenerating rat liver and hepatoma].
Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Rats | 1958 |
METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION.
Topics: Adrenalectomy; Carbon Isotopes; Carcinoma, Hepatocellular; Cortisone; Hypophysectomy; Liver; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; Oxygenases; Phenylalanine; Portacaval Shunt, Surgical; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tryptophan; Tryptophan Oxygenase | 1964 |
RELATION BETWEEN EXPERIMENTAL HEPATOCARCINOGENESIS AND CIRRHOSIS.
Topics: Amino Alcohols; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver Cirrhosis; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Research; Toxicology | 1964 |
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; Liver; Liver Neoplasms; Methionine; Methylcholanthrene; Microsomes; Microsomes, Liver; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Polycyclic Compounds; Rats; Research; Zoxazolamine | 1963 |
ETHIONINE CARCINOGENESIS IN THE RAT.
Topics: Carbon Isotopes; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Ethionine; Glycine; Liver; Liver Neoplasms; Methionine; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; RNA; RNA, Neoplasm; Toxicology | 1965 |
[Synthesis of methionine in presence of homogenates of liver of rats treated with 4-dimethylaminoazobenzene].
Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; p-Dimethylaminoazobenzene; Rats | 1959 |
Prevention by methionine of dichloroacetic acid-induced liver cancer and DNA hypomethylation in mice.
Topics: Adenoma, Liver Cell; Animals; Chlorine; Dichloroacetic Acid; DNA Methylation; Drug Combinations; Female; Glycogen; Hepatocytes; Liver Neoplasms; Methionine; Mice; Mice, Inbred Strains; Organ Size; Peroxisome Proliferators; Peroxisomes; Water Purification | 2004 |
Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.
Topics: Animals; Apolipoprotein A-I; Carcinoma, Hepatocellular; Chromatography, Liquid; Hepatitis B; Humans; Liver Diseases; Liver Neoplasms; Mass Spectrometry; Methionine; Mice; Neoplasm Proteins; Oxidation-Reduction; Protein Isoforms; Proteome; Tryptophan; Up-Regulation | 2005 |
Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells.
Topics: Actin Depolymerizing Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoskeletal Proteins; Electron-Transferring Flavoproteins; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Proteins; Gene Expression Profiling; Humans; Interleukin-1; Interleukin-1beta; Interleukin-6; Liver Neoplasms; Membrane Proteins; Methionine; Protein Biosynthesis; Proteins; Sulfur Isotopes; Superoxide Dismutase; Up-Regulation | 2006 |
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
Topics: Allosteric Regulation; Animals; Carcinoma, Hepatocellular; Cell Line; Cystathionine beta-Synthase; Enzyme Stability; Fatty Liver; Gene Silencing; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Knockout; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine | 2006 |
A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats.
Topics: Animals; Choline Deficiency; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Folic Acid Deficiency; Gene Silencing; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Inbred F344; Transcription Factors | 2006 |
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Diet; Folic Acid Deficiency; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methionine; Microarray Analysis; MicroRNAs; Rats; Rats, Inbred F344 | 2006 |
Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; DNA Methylation; DNA, Neoplasm; Genes, myc; Genomic Instability; Humans; Immunoblotting; Liver; Liver Neoplasms; Methionine; Mice; Mice, Transgenic; Prognosis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Transforming Growth Factor alpha | 2007 |
Usefulness of 11C-methionine for differentiating tumors from granulomas in experimental rat models: a comparison with 18F-FDG and 18F-FLT.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Diagnosis, Differential; Dideoxynucleosides; Fluorodeoxyglucose F18; Granuloma; Inflammation; Liver Neoplasms; Male; Methionine; Mycobacterium bovis; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Turpentine | 2008 |
The effects of casein and methionine on the retention of hepatic riboflavin and on the development of liver tumors in rats fed certain azo dyes.
Topics: Animals; Azo Compounds; Caseins; Coloring Agents; Liver Neoplasms; Methionine; Organic Chemicals; Rats; Riboflavin | 1949 |
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
Topics: Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Glycine N-Methyltransferase; Histones; Janus Kinases; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice; Mice, Knockout; Promoter Regions, Genetic; ras Proteins; S-Adenosylmethionine; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Transaminases; Tumor Suppressor Proteins | 2008 |
Scintigrams in the diagnosis of hepatic neoplasia. Use of colloidal radioactive gold and of 75-selenium-methionine.
Topics: Gold Colloid, Radioactive; Humans; Liver Function Tests; Liver Neoplasms; Methionine; Neoplasm Metastasis; Pancreatic Neoplasms; Radiography; Radionuclide Imaging; Selenium | 1967 |
Characterization of nascent and secreted thyroxine-binding globulin in cultured human hepatoma (Hep G2) cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Weight; Protein Biosynthesis; Sulfur Radioisotopes; Thyroxine-Binding Proteins | 1984 |
Infusion of branched chain amino acids after partial hepatectomy in man.
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Carcinoma, Hepatocellular; Female; Hepatectomy; Humans; Infusions, Parenteral; Kinetics; Liver Diseases; Liver Neoplasms; Male; Methionine; Middle Aged; Phenylalanine; Tyrosine | 1984 |
Regulation of rat alpha-fetoprotein production by methionine during ethionine-hepatocarcinogenesis.
Topics: alpha-Fetoproteins; Animals; Diet; Ethionine; Female; Liver Neoplasms; Methionine; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Dexamethasone regulates the program of secretory glycoprotein synthesis in hepatoma tissue culture cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dexamethasone; Fucose; Glycoproteins; Liver; Liver Neoplasms; Membrane Proteins; Methionine; Molecular Weight; Rats | 1980 |
Impaired metabolism of methionine in severe liver diseases. I. Clinical and pathophysiological significance of elevated serum methionine levels.
Topics: Amino Acids; Carcinoma, Hepatocellular; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Prognosis | 1982 |
In vitro effects of antitumor antibody--chemotactic factor complexes.
Topics: Animals; Antibodies, Neoplasm; Carbodiimides; Carcinoma, Hepatocellular; Chemotactic Factors; Cytotoxicity, Immunologic; Female; Guinea Pigs; Immunoglobulin G; Interleukin-8; Liver Neoplasms; Macrophages; Male; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neoplasms, Experimental; Oligopeptides; Rabbits | 1982 |
Fibronectin synthesized by a human hepatoma cell line.
Topics: Carcinoma, Hepatocellular; Cell Line; Fibronectins; Fluorescent Antibody Technique; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoelectrophoresis, Two-Dimensional; Liver Neoplasms; Methionine; Sulfur Radioisotopes | 1984 |
Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine.
Topics: Animals; Cell Nucleus; Choline Deficiency; Free Radicals; Lipid Peroxides; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Inbred F344 | 1984 |
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet.
Topics: Animals; Cell Nucleus; Choline Deficiency; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Influence of dietary lipotrope and lipid content on aflatoxin B1, N-2-fluorenylacetamide, and 1,2-dimethylhydrazine carcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Choline; Choline Deficiency; Diet; Dietary Fats; Dimethylhydrazines; Gastrointestinal Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methionine; Neoplasms, Experimental; Rats | 1980 |
Human hepatoma cell mutant defective in cell surface protein trafficking.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Biological Transport; Carcinoma, Hepatocellular; Cell Compartmentation; Drug Resistance; Endocytosis; Endosomes; Gene Expression; Humans; Liver Neoplasms; Methionine; Mutation; Orosomucoid; Phenotype; Plant Proteins; Protein Processing, Post-Translational; Receptors, Cell Surface; Ribosome Inactivating Proteins, Type 1; Selection, Genetic; Tumor Cells, Cultured | 1995 |
Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes.
Topics: Amino Acid Sequence; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Cisplatin; Clone Cells; Cytosol; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Humans; KB Cells; Liver Neoplasms; Methionine; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured | 1995 |
Levels of amino acids in human hepatocellular carcinoma and adjacent liver tissue.
Topics: Aged; Amino Acids; Carcinoma, Hepatocellular; Cystine; Glycine; Humans; Liver; Liver Neoplasms; Methionine; Middle Aged | 1995 |
Characterization of glutathione efflux from Hep G2 cells.
Topics: Adenosine Triphosphatases; Carcinoma, Hepatocellular; Cell Line; Epidermal Growth Factor; Glutathione; Humans; Insulin; Liver Neoplasms; Methionine; Potassium Channels; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured | 1994 |
The modulation of apolipoprotein E gene expression by 3,3'-5-triiodothyronine in HepG2 cells occurs at transcriptional and post-transcriptional levels.
Topics: Apolipoproteins E; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cycloheximide; Gene Expression Regulation; Humans; Kinetics; Liver Neoplasms; Methionine; Orosomucoid; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured | 1994 |
Biogenesis of the hepatitis B viral middle (M) surface protein in a human hepatoma cell line: demonstration of an alternative secretion pathway.
Topics: Autoradiography; Base Sequence; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Codon; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glycosylation; Hepatitis B; Hepatitis B virus; Humans; Kinetics; Liver Neoplasms; Methionine; Mutagenesis; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Viral; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins; Virion | 1994 |
Assembly pathway of avian infectious laryngotracheitis virus.
Topics: Animals; Carcinoma, Hepatocellular; Chickens; DNA, Viral; Herpesvirus 2, Gallid; Liver Neoplasms; Marek Disease; Methionine; Microscopy, Electron; Morphogenesis; Thymidine; Tumor Cells, Cultured; Viral Proteins | 1993 |
Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Amino Acids, Sulfur; Animals; Cell Count; Cysteine; Cystine; Glutathione; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tumor Cells, Cultured | 1994 |
Retrovirus-mediated gene transfer of transthyretin and transthyretin-methionine 30: a potential tool for the study of amyloidogenesis.
Topics: 3T3 Cells; Amyloid; Amyloidosis; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line; DNA; Gene Transfer Techniques; Genetic Vectors; Humans; Liver Neoplasms; Methionine; Mice; Molecular Sequence Data; Molecular Weight; Moloney murine leukemia virus; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Polymerase Chain Reaction; Prealbumin; Rats; Repetitive Sequences, Nucleic Acid; Retroviridae; Tumor Cells, Cultured | 1993 |
Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins.
Topics: Amino Acid Sequence; Animals; Apolipoprotein B-100; Apolipoproteins B; Base Sequence; Cell Line; Codon; DNA Primers; DNA, Complementary; Humans; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Rats; Restriction Mapping; Sequence Deletion; Sulfur Radioisotopes; Tumor Cells, Cultured | 1994 |
Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.
Topics: Carcinoma, Hepatocellular; Gene Expression; Heat-Shock Proteins; Hot Temperature; Humans; Kinetics; Liver Neoplasms; Methionine; RNA, Messenger; Sulfur Radioisotopes; Tumor Cells, Cultured | 1993 |
The secretory pathway is normal in dithiothreitol-treated cells, but disulfide-bonded proteins are reduced and reversibly retained in the endoplasmic reticulum.
Topics: alpha 1-Antitrypsin; Asialoglycoprotein Receptor; Asialoglycoproteins; Autoradiography; Calcimycin; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cysteine; Disulfides; Dithiothreitol; Endoplasmic Reticulum; Humans; Liver Neoplasms; Macromolecular Substances; Methionine; Neoplasm Proteins; Oxidation-Reduction; Receptors, Immunologic; Ribonucleases; Serum Albumin; Subcellular Fractions; Sulfur Radioisotopes; Transferrin; Tumor Cells, Cultured | 1993 |
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12 | 1993 |
Biogenesis of the covalently flavinylated mitochondrial enzyme dimethylglycine dehydrogenase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Dimethylglycine Dehydrogenase; Flavin-Adenine Dinucleotide; Gene Expression; Hepatoblastoma; Humans; Kinetics; Liver Neoplasms; Methionine; Mitochondria, Liver; Mitochondrial Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidoreductases, N-Demethylating; Protein Biosynthesis; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured | 1996 |
Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells.
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Humans; Immunoglobulin G; Kinetics; Liver Neoplasms; Methionine; Microsomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1996 |
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme Oxygenase (Decyclizing); Liver Neoplasms; Male; Methionine; Niacin; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin A; Vitamin E; Vitamin E Deficiency; Vitamins; Weight Gain | 1997 |
Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.
Topics: Affinity Labels; Animals; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Cattle; Cells, Cultured; Cysteine; Humans; Indoles; Isoindoles; Kinetics; Liver; Liver Neoplasms; Methionine; Microsomes; Microsomes, Liver; Piperidines; Rats; Sulfur Radioisotopes; Triglycerides; Tumor Cells, Cultured; Ultraviolet Rays | 1998 |
Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma.
Topics: Arginine; Blotting, Southern; Carcinoma, Hepatocellular; DNA, Neoplasm; Glycine; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Mutation; Threonine | 1999 |
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Enzymes; Humans; Isoenzymes; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; RNA, Messenger | 2000 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12 | 1975 |
Cytologic changes induced in rat livers cells by short-term exposure to chemical substances.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Butanes; Carcinogens; Chromosome Aberrations; DDT; Diethylnitrosamine; Diploidy; Hepatectomy; Hexachlorocyclohexane; Hydrazines; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Mitosis; Nitroso Compounds; Rats | 1975 |
[Achievements and perspectives of radioisotope diagnosis of malignant tumors (according to materials in the "Journal of Nuclear Medicine", 1974)].
Topics: Actinoid Series Elements; Animals; Antigens, Neoplasm; Bleomycin; Breast Neoplasms; Female; Gallium Radioisotopes; Humans; Indium; Iodine Radioisotopes; Isotope Labeling; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Metals, Rare Earth; Methionine; Mice; Neoplasms; Radioisotopes; Radionuclide Imaging; Selenium; Technetium; Ytterbium | 1976 |
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylnitrosamine; Esophageal Neoplasms; Folic Acid; Hemangioendothelioma; Lipotropic Agents; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Nicotinic Acids; Nitrosamines; Rats | 1977 |
S-adenosylmethionine:protein methyltransferases in hepatomas.
Topics: Adenine; Animals; Arginine; Carcinoma, Hepatocellular; Cell Nucleus; Cytosol; Histones; Liver; Liver Neoplasms; Lysine; Methionine; Methyltransferases; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Rats; Sulfuric Acids | 1975 |
[Diagnosis of primary hepatocellular carcinoma with 99mTc-acetylmethyonine].
Topics: Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Radionuclide Imaging; Technetium | 1975 |
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine | 1975 |
Partial purification and characterization of tumor and liver S-adenosylmethionine synthetases.
Topics: Animals; Carcinoma, Hepatocellular; Female; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasms, Experimental; Phosphates; Rats; Transferases; tRNA Methyltransferases | 1977 |
Labeling of hepatitis B virus surface antigen (HBsAg) synthesized in a HBsAg-producing hepatoma cell line.
Topics: Carcinoma, Hepatocellular; Cell Line; Cystine; Cytoplasm; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Molecular Weight; Peptides; Sulfur Radioisotopes | 1979 |
Specificity of the glutamine-binding site involved in the reguation of glutamine-synthetase activity in hepatoma tissue-culture cells.
Topics: Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Diazooxonorleucine; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Methionine; Neoplasms, Experimental; Sulfones | 1975 |
The influence of DL-methionine on the metabolism of S-adenosylethionine in rats chronically treated with DL-ethionine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Body Weight; Circadian Rhythm; Ethionine; Feeding Behavior; Female; Liver; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1976 |
Mechanism of suppressive effect of basic cupric acetate on rat liver carcinogenesis by ethionine.
Topics: Adenosine; Alkylation; Animals; Copper; Drug Interactions; Ethionine; Liver; Liver Neoplasms; Male; Methionine; Microsomes, Liver; Neoplasms, Experimental; Rats; RNA, Transfer | 1976 |
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms | 1975 |
The effect of ethionine on ribonucleic acid synthesis in rat liver.
Topics: Adenosine Triphosphate; Animals; Cycloheximide; Ethionine; Female; HeLa Cells; Inosine; Liver; Liver Neoplasms; Methionine; Methylation; Mitoguazone; Rats; RNA; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine | 1975 |
A comparison of the ability of normal liver, a premalignant liver, a solid hepatoma and the Zajdela ascitic hepatoma, to take up amino acids in vitro.
Topics: Amino Acids; Animals; Arginine; In Vitro Techniques; Kinetics; Leucine; Liver; Liver Neoplasms; Lysine; Methionine; Phenylalanine; Precancerous Conditions; Valine | 1976 |
The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins.
Topics: Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Humans; Kinetics; Lipoproteins; Liver Neoplasms; Methionine; Protein Biosynthesis; Sulfur Radioisotopes; Transfection | 1992 |
Identification of subcellular compartments involved in biosynthetic processing of cathepsin D.
Topics: alpha 1-Antitrypsin; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Golgi Apparatus; Horseradish Peroxidase; Humans; Kinetics; Liver Neoplasms; Methionine; Protein Processing, Post-Translational; Subcellular Fractions; Sulfur Radioisotopes | 1992 |
The effects of vitamin K1 and warfarin on prothrombin expression in human hepatoblastoma (HepG2) cells.
Topics: Antigens; Blotting, Northern; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Nucleic Acid Hybridization; Precipitin Tests; Prothrombin; RNA, Messenger; Sulfur Radioisotopes; Transcription, Genetic; Tumor Cells, Cultured; Vitamin K 1; Warfarin | 1992 |
Liver DNA adducts in methyl-deficient rats administered a single dose of aflatoxin B1.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biotransformation; Choline Deficiency; Diet; DNA; DNA Repair; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Precancerous Conditions; Rats; Rats, Inbred F344 | 1992 |
NF-AB, a liver-specific and cytokine-inducible nuclear factor that interacts with the interleukin-1 response element of the rat alpha 1-acid glycoprotein gene.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cytokines; Dexamethasone; Genes; Humans; Interleukin-1; Interleukin-6; Kidney; Kinetics; Liver; Liver Neoplasms; Methionine; Molecular Weight; Nuclear Proteins; Orosomucoid; Protein Binding; Rats; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Transfection | 1991 |
Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetophenones; Carcinoma, Hepatocellular; Cell Survival; Chromatography, Gel; Cycloheximide; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Hydrolysis; Isoflurophate; L-Lactate Dehydrogenase; Liver Neoplasms; Methionine; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Precipitin Tests; Tumor Cells, Cultured | 1991 |
Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells.
Topics: Amino Acid Sequence; Autoradiography; Butyrates; Butyric Acid; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Sulfur Radioisotopes | 1991 |
[35S]methionine interaction with rat liver tRNA and effect of chemical carcinogens.
Topics: Animals; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA; Ethionine; Hepatectomy; Liver; Liver Neoplasms; Male; Methionine; Methylnitrosourea; Rats; Rats, Inbred Strains; Reference Values; RNA, Transfer; Sulfur Radioisotopes; Tissue Distribution | 1991 |
Enhanced expression of a 27 kD protein during diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Animals; Cadmium; Diethylnitrosamine; Female; Fluorescence; Heat-Shock Proteins; Liver Neoplasms; Methionine; Molecular Weight; Neoplasm Proteins; Rats; Rats, Inbred Strains | 1990 |
Bromoconduritol treatment delays intracellular transport of secretory glycoproteins in human hepatoma cell cultures.
Topics: Carcinoma, Hepatocellular; Cell Line; Cyclohexenes; Glucosidases; Glycoproteins; Humans; Inositol; Kinetics; Liver Neoplasms; Methionine; Neoplasm Proteins; Protein Processing, Post-Translational; Tumor Cells, Cultured | 1989 |
3-Aminobenzamide inhibits poly(ADP ribose) synthetase activity and induces phosphoenolpyruvate carboxykinase (GTP) in H4IIE hepatoma cells.
Topics: Adenosine Diphosphate Ribose; Benzamides; Carcinoma, Hepatocellular; Cyclic AMP; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Immunosorbent Techniques; Liver Neoplasms; Methionine; Phosphoenolpyruvate Carboxykinase (GTP); Poly(ADP-ribose) Polymerase Inhibitors; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured | 1988 |
Regulation of apoprotein synthesis and secretion in the human hepatoma Hep G2. The effect of exogenous lipoprotein.
Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Apolipoproteins E; Apoproteins; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cholesterol; Chylomicrons; Electrophoresis, Polyacrylamide Gel; Fatty Acids, Nonesterified; Immunosorbent Techniques; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Liposomes; Liver Neoplasms; Methionine; Triglycerides; Tumor Cells, Cultured | 1988 |
Synthesis and secretion of protein C inhibitor by the human hepatoma-derived cell line, Hep G2.
Topics: Blood Proteins; Carcinoma, Hepatocellular; Cell Line; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Liver Neoplasms; Methionine; Molecular Weight; Protein C Inhibitor | 1985 |
Synthesis and processing of human serum apolipoprotein AII in vitro and in Hep G2 cells.
Topics: Amino Acid Sequence; Apolipoprotein A-II; Apolipoproteins A; Carcinoma, Hepatocellular; Cell-Free System; Cells, Cultured; Cysteine; Endoplasmic Reticulum; Humans; Liver; Liver Neoplasms; Methionine; Pancreas; Precipitin Tests; Protein Biosynthesis; RNA, Messenger | 1985 |
Pulse-chase studies of the synthesis of apolipoprotein B in a human hepatoma cell line, Hep G2.
Topics: Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Humans; Immunochemistry; Liver Neoplasms; Methionine; Molecular Weight; Peptide Biosynthesis; Sulfur Radioisotopes; Time Factors | 1985 |
Biosynthesis of functionally active heparin cofactor II by a human hepatoma-derived cell line.
Topics: Antibody Specificity; Carcinoma, Hepatocellular; Cell Line; Dermatan Sulfate; Glycoproteins; Heparin; Heparin Cofactor II; Humans; Immunoelectrophoresis; Liver Neoplasms; Methionine; Molecular Weight; Thrombin | 1985 |
Enhanced phosphatidylinositol kinase activity is associated with early stages of hepatocarcinogenesis and hepatocellular carcinoma.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methionine; Phosphotransferases; Precancerous Conditions; Rats; Rats, Inbred F344 | 1985 |
Effect of the antileukemic agent L-asparaginase on thyroxine-binding globulin and albumin synthesis in cultured human hepatoma (HEP G2) cells.
Topics: Asparaginase; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA Replication; Humans; Liver Neoplasms; Methionine; Serum Albumin; Thyroxine-Binding Proteins; Time Factors | 1986 |
Catabolic properties of aglycofibrinogen synthesized by tunicamycin-treated human hepatoma (HepG2) cells and rabbit hepatocytes.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Fibrinogen; Humans; Hydrolysis; Liver; Liver Neoplasms; Methionine; Oligosaccharides; Rabbits; Tunicamycin | 1986 |
Intracellular modifications of human apolipoprotein E.
Topics: Apolipoproteins E; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Macrophages; Methionine; Monensin; Monocytes; Sulfur Radioisotopes | 1986 |
Very low and low density lipoprotein synthesis and secretion by the human hepatoma cell line Hep-G2: effects of free fatty acid.
Topics: Acetates; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Methionine; Mevalonic Acid; Oleic Acid; Oleic Acids; Phospholipids; Serum Albumin, Bovine; Triglycerides | 1986 |
Lipotropic factors and oncogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Vitamin B 12 Deficiency | 1986 |
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets.
Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1986 |
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Male; Methionine; Phenobarbital; Prohibitins; Rats; Rats, Inbred F344; Weaning | 1986 |
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine | 1974 |
A lipotrope-dependent increase of histidase and urocanase in the livers of choline-deficient rats and in the Reuber H-35 transplanted hepatoma.
Topics: Ammonia-Lyases; Animals; Carcinoma, Hepatocellular; Choline; Choline Deficiency; Diet; Histidine Ammonia-Lyase; Hydro-Lyases; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Time Factors; Urocanate Hydratase; Vitamin B 12 | 1973 |
Hepatorenal lesions in rats fed a low lipotrope diet and exposed to aflatoxin.
Topics: Aflatoxins; Animals; Autoradiography; Body Weight; Choline; Diet; DNA; Hyperplasia; Kidney; Lipids; Lipotropic Agents; Liver; Liver Neoplasms; Male; Methionine; Rats; Thymidine; Tritium; Vitamin B 12 | 1968 |
S-adenosylmethionine-synthesizing activity of normal and neoplastic mouse tissues.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Estrogens; Female; Glucosyltransferases; Liver; Liver Neoplasms; Methionine; Mice; Neoplasms, Experimental; Rabbits; Testosterone | 1966 |
Cystathioninuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carcinoma, Hepatocellular; Child, Preschool; Cysteine; Diet Therapy; Female; Galactosemias; Glycogen; Humans; Infant; Intellectual Disability; Liver Neoplasms; Male; Maple Syrup Urine Disease; Methionine; Middle Aged; Neuroblastoma; Phenylketonurias; Portal Vein; Pyridoxine; Serine; Sulfisoxazole; Tyrosine | 1967 |
Utilization of L-methionine and S-adenosyl-L-methionine for methylation of soluble RNA by mouse liver and hepatoma extracts.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alkylation; Animals; Bacillus subtilis; Carbon Isotopes; Carcinoma, Hepatocellular; Escherichia coli; Female; Fishes; Liver; Liver Neoplasms; Male; Methionine; Mice; Neoplasms, Experimental; Nucleosides; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Tritium; Yeasts | 1967 |
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides | 1968 |
S-adenosylmethionine synthetase activity in some normal rat tissues and transplantable hepatomas.
Topics: Adenosine Triphosphate; Animals; Brain; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, Paper; Epididymis; Female; Kidney; Liver; Liver Neoplasms; Male; Methionine; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sex Factors; Spectrum Analysis; Testis; Transferases | 1968 |
Studies on DNA methylase activity in mammalian tissue.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Edetic Acid; Liver; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Quaternary Ammonium Compounds; Salmonidae; Testis; Transferases | 1969 |
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine | 1969 |
The distribution and concentration of 75Se-selenomethionine in man.
Topics: Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Humans; Liver Neoplasms; Male; Methionine; Radioisotopes; Selenium | 1969 |
Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Densitometry; Electrophoresis; Formates; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleotides; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides | 1969 |
Methylation of transfer RNA and of ribosomal RNA in rat liver in the intact animal and the effect of carcinogens.
Topics: Aflatoxins; Animals; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Paper; Ethionine; Female; Intestine, Small; Kinetics; Liver; Liver Neoplasms; Male; Methionine; Methylation; Models, Biological; Models, Chemical; Nitrosamines; Nucleotides; Perchlorates; Precancerous Conditions; Protein Biosynthesis; Purinones; Rats; Ribosomes; RNA; RNA, Neoplasm; RNA, Transfer; Stimulation, Chemical; Time Factors | 1969 |
Natural inhibitors of the transfer ribonucleic acid methylases.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Dialysis; Drug Stability; Escherichia coli; Female; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Omentum; Pregnancy; Quaternary Ammonium Compounds; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Trypsin; Ultracentrifugation | 1970 |
Development of resistance of Novikoff hepatoma to 5-fluoro-2'-deoxyuridine.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Floxuridine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Thymidine; Thymine; Tritium | 1970 |
Methylation of preribosomal and transfer RNA's by isolated nucleoli of the Novikoff rat tumor.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Transfer; Tritium | 1970 |
75se-selenomethionine in the scintiscan diignosis of primary hepatocellular carcinoma.
Topics: Adenoma, Bile Duct; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methionine; Neoplasm Metastasis; Radionuclide Imaging; Selenium | 1971 |
Methylation of mammalian deoxyribonucleic acid. II. The distribution of 5-methylcytosine in pyrimidine deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.
Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Techniques; Cytosine; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA, Neoplasm; Formates; Hydrolysis; Liver Neoplasms; Methionine; Methods; Methylation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; Snakes; Spectrophotometry; Thymine Nucleotides; Venoms | 1971 |
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors | 1971 |
Diagnosis of hepatoma using a multiple radionuclide approach.
Topics: Angiography; Biopsy; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Male; Methionine; Methods; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium; Serum Albumin, Radio-Iodinated; Technetium | 1972 |
Transfer ribonucleic acid methylases of nucleoli isolated from a rat tumor.
Topics: Ammonium Chloride; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Escherichia coli; Kinetics; Liver Neoplasms; Magnesium; Methionine; Methyltransferases; Neoplasms, Experimental; Osmolar Concentration; Polynucleotides; Rats; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship; Subcellular Fractions; Tritium | 1972 |
Methylation patterns of transfer RNA from ascites hepatomas.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine Nucleotides; Guanine Nucleotides; Inosine Nucleotides; Liver; Liver Neoplasms; Methionine; Methylation; Nucleotides; Rats; RNA, Transfer; Tritium; Uracil Nucleotides | 1972 |
Methylation of mammalian deoxyribonucleic acid. 3. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff hepatoma cell deoxyribonucleic acid.
Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Clone Cells; Cytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Escherichia coli; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats; Spleen; Venoms | 1972 |
Action of ethionine, methionine, ATP, adenine, albumin and Ca 2+ on protein synthesis of normal and tumor cells.
Topics: Adenine; Adenosine Triphosphate; Albumins; Amino Acids; Analysis of Variance; Animals; Calcium; Carbon Isotopes; Carcinoma, Hepatocellular; Cells; Edetic Acid; Ethionine; Female; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1972 |
Uptake of 75 Se-selenomethionine by hepatoma.
Topics: Aged; Carcinoma, Hepatocellular; Colloids; Female; Humans; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Sulfur; Technetium | 1972 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
Hepatocellular carcinoma. Clinical and laboratory observations.
Topics: Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Carcinoma, Hepatocellular; Colloids; Fetal Proteins; Humans; Immunodiffusion; Iodine Radioisotopes; Liver Neoplasms; Male; Methionine; Middle Aged; Radionuclide Imaging; Rose Bengal; Selenium; Sulfur Isotopes; Technetium | 1972 |
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen | 1972 |
[Double hepatic scintigraphy (gold-selenomethionine) in the diagnosis of primary tumors of the liver].
Topics: Carcinoma, Hepatocellular; Gold Isotopes; Humans; Liver Neoplasms; Methionine; Methods; Radionuclide Imaging; Selenium | 1972 |
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine | 1973 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
The radiological and scintigraphic investigation of spontaneous hypoglycaemia.
Topics: Abdominal Neoplasms; Adenoma, Islet Cell; Adult; Female; Fibrosarcoma; Humans; Hypoglycemia; Liver Neoplasms; Male; Methionine; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Prognosis; Radiography; Radioisotopes; Radionuclide Imaging; Retroperitoneal Neoplasms; Selenium; Technetium | 1973 |
[Scintiphotography of primary hepatocellular carcinoma with 75Se-selenomethionine (author's transl)].
Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium | 1973 |
Studies of initiation factors in protein synthesis of host liver and transplantable hepatoma.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Poly U; Protein Binding; Rats; Ribosomes; RNA, Ribosomal; RNA, Transfer; Transplantation, Homologous | 1974 |
Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Mercaptopurine; Methionine; Neoplasms, Experimental; Nitriles; Pyrimidines; Pyrroles; Ribonucleosides; RNA, Neoplasm; RNA, Ribosomal; Tritium; Uridine | 1974 |
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine | 1974 |
The enzymology of methionine metabolism in rat hepatomas.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Dietary Proteins; Liver; Liver Neoplasms; Male; Methionine; Methyltransferases; Neoplasms, Experimental; Rats; Transferases | 1974 |
Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue.
Topics: Aminoisobutyric Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cytosine; DNA; DNA, Neoplasm; Female; Formates; Hepatectomy; Liver Neoplasms; Liver Regeneration; Methionine; Neoplasms, Experimental; Rats; RNA; RNA, Neoplasm; Thymine; Tritium | 1974 |
[A new method for the isotopic diagnosis of primary hepatomas using selenomethionine].
Topics: Carcinoma, Hepatocellular; Colloids; Humans; Liver Neoplasms; Methionine; Methods; Neoplasm Metastasis; Radionuclide Imaging; Selenium; Statistics as Topic; Technetium | 1973 |
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine | 1972 |
Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.
Topics: Albumins; Animals; Anti-Bacterial Agents; Calcium; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Kinetics; Leucine; Liver; Liver Neoplasms; Magnesium; Methionine; Mitochondria, Liver; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Potassium; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Transplantation, Homologous | 1974 |
The use of multiple radionuclide imaging to differentiate the focal intrahepatic lesion.
Topics: Carcinoma, Hepatocellular; Cysts; Hemangioma; Humans; Indium; Isotopes; Liver Abscess; Liver Circulation; Liver Diseases; Liver Neoplasms; Methionine; Radiography; Radioisotopes; Radionuclide Imaging; Selenium | 1974 |
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases | 1974 |
75 Se-selenomethionine in hepatic focal lesions.
Topics: Angiography; Carcinoma; Cysts; Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Liver; Liver Abscess; Liver Abscess, Amebic; Liver Diseases; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methionine; Neoplasm Metastasis; Pancreas; Radioisotopes; Radionuclide Imaging; Selenium; Subtraction Technique | 1972 |
[Use of methionine-Se75 for studying metabolic processes in the liver].
Topics: Female; Humans; Liver; Liver Diseases; Liver Neoplasms; Male; Methionine; Radioisotopes; Radionuclide Imaging; Selenium | 1972 |
False-negative 75Se-selenomethionine scans in primary liver cancer.
Topics: Colloids; Cysts; False Negative Reactions; Humans; Liver Diseases; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Sulfur; Technetium | 1974 |
Transfer ribonucleic acid methylases in normal tissues and in tumours.
Topics: Animals; Carbon Isotopes; Chromatography; Escherichia coli; Hepatectomy; Kidney Neoplasms; Liver Neoplasms; Liver Regeneration; Methionine; Methyltransferases; Neoplasms, Experimental; Nitrosamines; RNA, Bacterial; RNA, Transfer | 1971 |
[Specific detection of liver neoplasms using double labelling with selenomethionine-75 and colloidal gold-198].
Topics: Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Liver; Liver Diseases; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium | 1971 |
Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine.
Topics: Animals; Carbon Isotopes; Dactinomycin; Ethionine; Guanine; Liver; Liver Neoplasms; Male; Methionine; Methylation; Pyrimidines; Rats; Ribose; RNA, Bacterial; RNA, Transfer | 1972 |
[Original method of diagnosis of liver neoplasms: radioisotope scanning with selenomethionine].
Topics: Adolescent; Aged; Gold Colloid, Radioactive; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Radionuclide Imaging; Selenium | 1971 |
Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine.
Topics: Alkylation; Animals; Carcinogens; Chromatography, Ion Exchange; DNA; Ethionine; Guanine; Hydrolysis; Liver; Liver Neoplasms; Male; Methionine; Rats; Tritium | 1971 |
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.
Topics: Alkylation; Amino Acids; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Chromatography, Paper; Female; Formaldehyde; Histones; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Methionine; Methylation; Necrosis; Nitrosamines; Rats; S-Adenosylmethionine; Sulfonic Acids; Tritium | 1971 |
The value of scintiscanning in the diagnosis of hepatic tumours using both selenomethionine and technetium.
Topics: Humans; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Technetium | 1970 |
[Pepper type neuroblastoma with homocystinuria. Diagnosis, biochemistry and therapy].
Topics: Amino Acids; Catecholamines; Child, Preschool; Cyclophosphamide; Dopamine; Homocystinuria; Humans; Liver Neoplasms; Male; Methionine; Neoplasm Metastasis; Neuroblastoma; Norepinephrine; Normetanephrine; Phenylacetates; Pyridoxine; Serine; Stereoisomerism; Vanilmandelic Acid; Vincristine | 1970 |
[Probles in the positive cintigraphic diagnosis of abdomina tumors with 75Se-selenit].
Topics: Abdominal Neoplasms; Adult; Aged; Diagnosis, Differential; Female; Gallbladder Neoplasms; Gold Isotopes; Hemangioma; Humans; Injections, Intravenous; Liver Neoplasms; Male; Methionine; Methods; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Pancreas; Pancreatic Neoplasms; Radionuclide Imaging; Selenium | 1970 |
Clinical and experimental uses of radioisotopes in the diagnosis of cancer.
Topics: Bone Neoplasms; Brain Neoplasms; Calcium Isotopes; Cesium Isotopes; DNA; Eye Neoplasms; Fluorine; Gallium; Humans; Iodine Radioisotopes; Liver Neoplasms; Methionine; Neoplasms; Phosphorus Isotopes; Radionuclide Imaging; Rubidium; Selenium; Strontium Isotopes; Thyroid Neoplasms | 1968 |
[Scintigraphy of the liver, gallbladder and pancreas].
Topics: Arteriovenous Fistula; Gallbladder; Humans; Iodine Radioisotopes; Liver; Liver Cirrhosis; Liver Neoplasms; Malabsorption Syndromes; Methionine; Neoplasm Metastasis; Pancreas; Pancreatitis; Radioisotopes; Radionuclide Imaging; Selenium | 1968 |
[In vivo methylation of rat liver RNA and under the influence of diethylnitrosamine].
Topics: Animals; Carbon Isotopes; Carcinogens; Centrifugation, Zonal; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nitrosamines; Orotic Acid; Rats; Ribosomes; RNA; Tritium | 1968 |
[Quantitative studies on organ distribution following administration of various radioisotopes, using a 10-crystal scanner and computer scintigraphy].
Topics: Coloring Agents; Computers; Gold Colloid, Radioactive; Gold Isotopes; Humans; Iodine Radioisotopes; Kidney; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Methods; Neoplasm Metastasis; Pancreas; Radioisotopes; Radionuclide Imaging; Selenium | 1968 |
Starch-gel electrophoresis of human tissue enzymes which hydrolyze L-leucyl-beta-naphthylamide.
Topics: Amides; Amidohydrolases; Breast Neoplasms; Chemical Phenomena; Chemistry; Electrophoresis; Humans; In Vitro Techniques; Leucyl Aminopeptidase; Liver Neoplasms; Methionine; Naphthalenes | 1966 |