Page last updated: 2024-08-17

methionine and Cancer of Liver

methionine has been researched along with Cancer of Liver in 195 studies

Research

Studies (195)

TimeframeStudies, this research(%)All Research%
pre-1990113 (57.95)18.7374
1990's32 (16.41)18.2507
2000's18 (9.23)29.6817
2010's19 (9.74)24.3611
2020's13 (6.67)2.80

Authors

AuthorsStudies
Chen, D; Piao, H; Wang, W1
Agopian, V; Ayoub, W; Benhammou, JN; Choi, G; Dong, TS; Durazo, F; Elashoff, D; Enayati, P; Fiehn, O; Goodman, MT; Hussain, SK; Jacobs, JP; Lagishetty, V; Noureddin, M; Pisegna, JR; Sundaram, V1
Chen, PM; Chiang, EI; Huang, CC; Hwang, HH; Ko, HA; Li, JR; Liu, CC; Tsai, CH1
Fang, AP; He, TT; Liu, XZ; Liu, ZY; Luo, Y; Wusiman, M; Xiao, HW; Yishake, D; Zhu, HL1
Guo, H; Hu, R; Huang, L; Kong, X; Qian, Y; Sha, M; Xia, Q; Xu, D; Zhang, X; Zhang, Y1
Abe, A; Miyajima, K; Nakae, D; Nakane, S; Suzuki-Kemuriyama, N; Yuki, M1
Angulo, S; Carril, E; Godzien, J; Lanzón, B; Rupérez, FJ; Valdecantos, MP; Valverde, ÁM1
Antwi, SO; Campbell, PT; Liao, LM; McGlynn, KA; Norez, DA; Patel, T; Petrick, JL; Roberts, LR; Stevens, VL1
Deterding, LJ; Gao, X; Ji, M; Kang, K; Li, L; Li, X; Li, Y; Liu, J; Locasale, JW; Shats, I; Tong, L; Tong, X; Williams, JG; Xu, Q1
Guo, Z; Jin, C; Li, Y; Shao, J; Su, Y; Wang, S; Wang, X; Zhang, F; Zhang, Z; Zheng, S1
Badone, B; Bonanomi, M; Coccetti, P; Gaglio, D; Maffioli, E; Milanesi, R; Nonnis, S; Tedeschi, G; Tripodi, F; Vescovi, M1
Buechler, C; Haberl, EM; Höring, M; Krautbauer, S; Liebisch, G; Pohl, R; Rein-Fischboeck, L1
Budhu, A; Chaisaingmongkol, J; Chang, CW; Diggs, LP; Forgues, M; Greten, TF; Heinrich, S; Hung, MH; Lee, JS; Ma, C; Ma, L; Ruchirawat, M; Ruppin, E; Wang, XW1
Chen, XL; Chen, YM; Lan, QY; Liao, GC; Zhang, YJ; Zhou, RF; Zhou, ZG; Zhu, HL1
Channa, IS; Hashim, Z; Ilyas, A; Zarina, S1
Columbano, A; Orrù, C; Perra, A; Szydlowska, M; Taguchi, K; Yamamoto, M; Zavattari, P1
Corn, DJ; Kuang, Y; Lee, Z; Tian, H; Wang, F2
Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM1
Hatano, E; Koyama, Y; Nakamura, K; Seo, S; Takemoto, K; Tanabe, K; Taura, K; Toriguchi, K; Uemoto, S1
Barghash, A; Bohle, RM; Cadenas, C; Gemperlein, K; Gianmoena, K; Haybaeck, J; Helms, V; Hengstler, JG; Kessler, SM; Kiemer, AK; Lammert, F; Mueller, R; Pokorny, J; Simon, Y; van Rooijen, N; Zimmer, V1
Banwat, E; Chetwood, J; Crossey, MM; Dona, AC; Duguru, M; Fye, HK; Garside, DA; Holmes, E; Kasstan, B; Khan, SA; Ladep, NG; Lemoine, M; Lewis, MR; Nicholson, JK; Njai, HF; Njie, R; Okeke, E; Shimakawa, Y; Taal, M; Taylor-Robinson, SD; Thillainayagam, AV; Thursz, MR; Wijeyesekera, A1
Egger, M; Eggert, T; ElGindi, M; Felsher, DW; Greten, TF; Han, M; Heikenwalder, M; Jin, P; Kapoor, V; Kesarwala, AH; Kleiner, DE; Luo, J; Ma, C; McVicar, DW; Medina-Echeverz, J; Stroncek, DF; Terabe, M; Thornton, AM; Weber, A; Zhang, H1
Buechler, C; Eisinger, K; Haberl, EM; Krautbauer, S; Neumann, M; Pohl, R; Rein-Fischboeck, L; Weiss, TS; Zimny, S1
Bagnyukova, TV; Beland, FA; Muskhelishvili, L; Pogribny, IP; Ross, SA; Tryndyak, VP1
MILLER, EC; MILLER, JA1
Elias, MS; Green, RM; Henkel, AS1
Choi, SH; Kim, HY; Kim, JR; Kwak, GH1
Funabiki, R; Kawasaki, M; Miura, Y; Yagasaki, K1
Bosserhoff, AK; Dettmer, K; Hellerbrand, C; Kirovski, G; Oefner, PJ; Samejima, K; Stevens, AP1
Lu, SC; Mato, JM2
Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC1
Kaneoka, Y; Kumada, T; Maeda, A; Toyoda, H1
Beland, FA; James, SJ; Pogribny, IP1
Ahn, IY; Bae, JY; Bang, du Y; Han, EY; Jang, DE; Kim, DH; Kim, HS; Kim, KB; Kwack, SJ; Kwak, EH; Kwak, MY; Lee, BM; Lee, J; Lee, YJ; Lim, DS; Lim, SK; Park, KL; Roh, T; Yoo, SD1
Alberto, JM; Ayav, A; Bressenot, A; Bronowicki, JP; Chéry, C; Fofou-Caillierez, M; Forges, T; Guéant, JL; Namour, F; Pellanda, H1
Avila, MA; García-Trevijano, ER; Latasa, MU; Lu, SC; Martínez-Chantar, ML; Mato, JM; Varela-Rey, M1
Choudhury, P; Datta, B; Datta, R; Ghosh, A1
Ding, J; Guo, Z; He, C; Lin, J; Lin, L; Tu, C; Wang, X; Wang, Z; Yan, C; You, X; Zhang, J1
GIUDICE, G; MAGGIO, R; MUTOLO, V1
CHO, YS; MORRIS, HP; PITOT, HC1
FARBER, E1
KINOSITA, R; MIYAJI, H1
BURNS, JJ; CONNEY, AH1
DUNN, WL1
MANGIANTINI, M1
Kramer, PM; Pereira, MA; Tao, L; Wang, W1
Avila, MA; Caballería, J; Corrales, FJ; Fernández-Irigoyen, J; Lu, SC; Mato, JM; Muñoz, J; Prieto, J; Riezu, JI; Santamaría, E; Sesma, L1
Bierczyńska-Krzysik, A; Bonar, E; Dubin, A; Koj, A; Noga, M; Silberring, J; Stalińska, K1
Banerjee, R; Bauman, Z; Braun, A; Lu, SC; Prudova, A; Vitvitsky, V1
Bai, S; Datta, J; Ghoshal, K; Huang, Y; Jacob, ST; Li, X; Pogribny, I; Pogribny, M; Young, D1
Bai, S; Datta, J; Frankel, W; Ghoshal, K; Jacob, ST; Kutay, H; Motiwala, T; Pogribny, I1
Calvisi, DF; De Miglio, MR; De Murtas, V; Feo, F; Frau, M; Ladu, S; Muroni, MR; Pascale, RM; Pellegrino, R; Pinna, F; Simile, MM; Tomasi, ML; Virdis, P1
Kanegae, K; Kohanawa, M; Kuge, Y; Seki, K; Takahashi, T; Tamaki, N; Yi, M; Zhao, S; Zhao, Y1
BAUMANN, CA; CLAYTON, CC; GRIFFIN, AC1
Aransay, AM; Ariz, U; Calvisi, DF; Capdevila, A; Esteller, M; Fraga, M; Lu, SC; Luka, Z; Martínez, N; Martínez-Chantar, ML; Mato, JM; Matthiesen, R; Rodríguez, J; Varela, M; Vázquez-Chantada, M; Wagner, C; Yang, H1
Lu, SC; Martínez-Chantar, ML; Mato, JM1
Brown, CH; Filson, EJ; Mlecko, LM; Rodríguez-Antúnez, A1
Bartalena, L; Robbins, J; Tata, JR1
Hirose, S; Nagasue, N; Ogawa, Y; Sasaki, Y; Yukaya, H1
Miyazaki, M; Watanabe, A1
Baumann, H; Doyle, D; Gelehrter, TD1
Higashi, T1
Obrist, R; Sandberg, AL1
Colman, RW; Glasgow, JE1
Farber, E; Ghoshal, AK; Lim, YP; Rushmore, TH1
Poirier, LA; Shivapurkar, N; Wilson, MJ1
Lenhart, G; Morrison, G; Rogers, AE1
Potvin, B; Stanley, P; Stockert, RJ; Tao, L; Wolkoff, AW1
Endo, M; Goseki, N; Kando, F; Maruyama, M; Nagai, K; Shimoju, K; Wada, Y1
Akiyama, S; Gottesman, MM; Pastan, I; Schoenlein, P; Shen, DW1
Matsumata, T; Nishizaki, T; Sugimachi, K; Taketomi, A; Yamamoto, K1
Ahlström, H; Bergh, J; Jansson, T; Långström, B; Lilja, A; Westlin, JE1
Liu, J; Liu, JH; Marumo, F; Miyakawa, H; Mori, K; Sato, C; Takano, T1
Bereziat, G; Janvier, B; Loriette, C; Mangeney-Andreani, M; Vandenbrouck, Y1
Lo, SJ; Sheu, SY1
Poirier, LA3
Guo, P; Maloney, B; Nodgreen, R; Scholz, E; Turek, J1
Huang, HY; Lu, SC1
Bonifácio, MJ; Breakfield, XO; Ezzeddine, D; Sakaki, Y; Saraiva, MJ1
McLeod, RS; Selby, SL; Westerlund, J; Yao, Z; Zhao, Y1
Beck, SC; Buchman, TG; De Maio, A1
Kong, N; Lodish, HF1
Abileah, S; Christman, JK; Dizik, M; Sheikhnejad, G; Wainfan, E1
Brandsch, R; Otto, A; Sailer, HP; Stoltz, M1
Cederbaum, AI; Yang, MX1
Henning, SM; Swendseid, ME1
Henning, SM; Ivandic, BT; Liao, F; Swendseid, ME1
Biller, SA; Chen, Y; Chu, CH; Dickson, JK; Gordon, DA; Gregg, RE; Jamil, H; Wetterau, JR; Yan, M1
Chen, WN; Leong, AL; Oon, CJ; Teng, SW; Zhao, Y1
Avila, MA; Berasain, C; Caballería, J; Corrales, FJ; Lu, SC; Martín-Duce, A; Mato, JM; Prieto, J; Rodés, J; Torres, L; Yang, H1
Hitachi, PM; Takayama, S; Yamada, K1
Fateeva, MN; Zherbin, EA1
Rogers, AE1
Ezirike, J; Kim, S; Morris, HP; Paik, WK1
Ishikawa, R; Kusakabe, K; Maki, M; Ono, Y; Yamasaki, T1
Hilliard, JK; Sneider, TW1
Hurlbert, RB; Liau, MC; Lin, GW1
Alexander, JJ; Deinhardt, F; Frösner, GG; Hofschneider, PH; Zaslavsky, V1
Freikopf, A; Kulka, RG1
Altman, NH; Brada, Z; Bulba, S1
Kojima, S; Sakai, K; Yamane, Y1
Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y1
Swann, PF1
Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F1
Borén, J; Graham, L; Olofsson, SO; Scott, J; Wettesten, M; White, A1
Geuze, HJ; Rijnboutt, S; Stoorvogel, W; Strous, GJ1
Burkey, BF; Degen, SJ; Jamison, CS1
Laver, GW; McMullen, E; Mehta, R; Stapley, R1
Baumann, H; Won, KA1
Hiramoto, M; Imaizumi, T; Kawamura, Y; Satoh, K; Takamatsu, M; Takamatsu, S; Yoshida, H1
Donadel, G; Frank, R; Gabrielli, F; Garzelli, C1
Kanduc, D; Quagliariello, E1
Lyn-Cook, B; Poirier, LA; Zapisek, W1
Delhaye, M; Galand, P; Mairesse, N1
Newberne, PM; Rogers, AE1
Olden, K; Yeo, KT; Yeo, TK1
Beale, EG; Granner, DK; Leverence, RR1
Cooper, AD; Craig, WY; Nutik, R1
Hashimoto, S; Morito, F; Saito, H; Suzuki, K1
Blau, R; Burk, M; Stoffel, W1
Bondjers, G; Borén, J; Boström, K; Carrella, M; Jarfeldt, M; Norfeldt, PI; Olofsson, SO; Wettesten, M; Wiklund, O1
Armellino, D; Jaffe, EA; Tollefsen, DM1
Olson, JW1
Antonelli, A; Bartalena, L; Martino, E; Pacchiarotti, A; Pinchera, A; Robbins, J1
Barsigian, C; Base, W; Fish, S; Gilman, P; Martinez, J; Schaeffer, A1
Silverman, D; vanderSpek, J; Zannis, VI1
Cooper, AD; Ellsworth, JL; Erickson, SK1
Newberne, PM1
Creasia, D; Hoover, KL; Mikol, YB; Poirier, LA; Shivapurkar, N; Wilson, MJ1
Hoover, KL; Poirier, LA; Shivapurkar, N1
Gottschalk, A; Hoffer, PB1
Pitot, HC; Weiss, JW2
Morris, HP; Petri, WA; Poirier, LA1
Newberne, PM; Rogers, AE; Wogan, GN1
Hancock, RL2
Donnell, GN; Koch, R; Lieberman, E; Shaw, KN1
Busch, H; Nakamura, T; Prestayko, AW1
Bilik, E; Sheid, B2
Potter, VR; Sneider, TW1
Ben-Porath, M; Kaplan, E1
Busch, H; Hodnett, JL; Moriyama, Y; Prestayko, AW1
Craddock, VM2
Kerr, SJ1
Wolberg, WH1
Flatt, NC; Hurlbert, RB; Liau, MC1
Eddleston, AL; Osborn, SB; Pagaltsos, AP; Rake, MO; Williams, R1
Sneider, TW1
Byvoet, P2
Anderson, JE; Perlmutter, GS1
Hurlbert, RB; Liau, MC; O'Rourke, CM1
Inose, M; Iwanami, Y; Miyata, S1
Sneider, T1
Agostini, C; Comi, P; Mortara, G1
Stolzenberg, J1
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ1
Burdine, JA; Calderon, M; Goyal, RK; Grubb, MN; Hersh, T; Kaldenbaugh, H1
Bancons, J; Blanquet, P; Dubarry, JJ; Ducassou, D; Leccia, MF; Quinton, A1
Pitot, HC; Wilkinson, DS1
Davies, ER1
Kusakabe, K1
Murty, CN; Sidransky, H; Verney, E1
Nau, F1
Finkelstein, JD; Grossman, MR; Kyle, WE; Morris, HP1
Baliga, BS; Borek, E; Nielsen, HR; Nyholm, K; Sjolin, KE; Wong, R1
Bouali, AB; Cheguillaume, J; Joubaud, F; Minier, J; Pithon, G1
Howard, E; Tidwell, T1
Kartenbeck, J; Schreiber, G; Schreiber, M1
Johnson, PM; Muroff, LR1
Inose, M; Iwanami, Y1
Domingo, M; Kaplan, E1
Palinkashi, DG1
Geddes, EW; Kew, MC; Levin, J1
Caroli, J; de Saint-Laurent, J; Hadchouel, P; Milhaud, G1
Pegg, AE1
Caroli, J; de Saint-Laurent, J; Hadchouel, P; Milhaud, G; Theodoropoulos, G1
Farber, E; Hawks, A; Magee, PN; Pegg, AE; Swann, PF1
Craddock, VM; Turberville, C1
Eddleston, A; Osborne, SB; Pagaltsos, S; Rake, MO; Williams, R1
Käser, H; Mönch, E; Stefan, H1
Iwig, J; Schmalbach, J; Thiemann, KJ1
Ackerman, NB1
Schneider, C1
Kahle, P; Kessel, H; Kröger, H1
Hundeshagen, H1
Rutenburg, AM; Smith, EE1

Reviews

11 review(s) available for methionine and Cancer of Liver

ArticleYear
The hepatocarcinogenic effect of methionine and choline deficient diets: an adaptation to the Warburg effect?
    Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:5

    Topics: Adaptation, Physiological; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Humans; Liver Neoplasms; Methionine

2011
Molecular alterations in hepatocarcinogenesis induced by dietary methyl deficiency.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:1

    Topics: Animals; Deficiency Diseases; Diet; DNA Damage; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Lipid Metabolism; Liver Neoplasms; Methionine; MicroRNAs; Oxidative Stress

2012
ETHIONINE CARCINOGENESIS.
    Advances in cancer research, 1963, Volume: 7

    Topics: Bacteria; Carcinogenesis; Ethionine; Humans; Liver Neoplasms; Metabolism; Methionine; Neoplasms; Neoplasms, Experimental; Pharmacology; Toxicology

1963
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
    Alcohol (Fayetteville, N.Y.), 2005, Volume: 35, Issue:3

    Topics: Animals; Cell Death; Central Nervous System Depressants; Ethanol; Female; Hepatocytes; Humans; Isoenzymes; Liver; Liver Diseases, Alcoholic; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; S-Adenosylmethionine

2005
Methionine metabolism and liver disease.
    Annual review of nutrition, 2008, Volume: 28

    Topics: Animals; Choline; Choline Deficiency; Folic Acid Deficiency; Humans; Liver Diseases; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation

2008
Methyl group deficiency in hepatocarcinogenesis.
    Drug metabolism reviews, 1994, Volume: 26, Issue:1-2

    Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine

1994
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
    Advances in experimental medicine and biology, 1996, Volume: 399

    Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms

1996
Physiological methylation in carcinogenesis.
    Progress in clinical and biological research, 1990, Volume: 340D

    Topics: Animals; Choline Deficiency; DNA; Humans; Liver Neoplasms; Methionine; Methylation; Oxidation-Reduction; S-Adenosylmethionine

1990
Labile methyl groups and the promotion of cancer.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency

1986
Dietary methyl groups and cancer.
    Nutrition reviews, 1986, Volume: 44, Issue:8

    Topics: Animals; Choline Deficiency; Diet; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats

1986
Tumor scanning agents.
    Seminars in nuclear medicine, 1974, Volume: 4, Issue:3

    Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms

1974

Trials

2 trial(s) available for methionine and Cancer of Liver

ArticleYear
[Clinical evaluation of anticancer effect of methionine-depleting total parenteral nutrition with 5-fluorouracil and/or mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:8

    Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Mitomycin; Parenteral Nutrition, Total; Stomach Neoplasms

1995
Positron emission tomography studies in patients with locally advanced and/or metastatic breast cancer: a method for early therapy evaluation?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbon Radioisotopes; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Lymphatic Metastasis; Methionine; Tomography, Emission-Computed

1995

Other Studies

182 other study(ies) available for methionine and Cancer of Liver

ArticleYear
[Identification of
    Se pu = Chinese journal of chromatography, 2021, Volume: 39, Issue:10

    Topics: Animals; Carcinoma, Hepatocellular; Chromatography, Liquid; Disease Models, Animal; Inflammation; Liver; Liver Neoplasms; Mass Spectrometry; Methionine; Mice

2021
Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:8

    Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Microbiota; Proportional Hazards Models; Prospective Studies; Risk Factors; Taurocholic Acid

2022
Downregulation of Methionine Cycle Genes
    International journal of molecular sciences, 2022, Jan-01, Volume: 23, Issue:1

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Down-Regulation; Eukaryotic Initiation Factor-3; Gene Expression Regulation, Neoplastic; Glycine N-Methyltransferase; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasm Invasiveness; Peptide Elongation Factor 1; Promoter Regions, Genetic; Protein Biosynthesis; Survival Analysis

2022
Dietary intake of one-carbon metabolism-related nutrients and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort.
    Food & function, 2022, Aug-01, Volume: 13, Issue:15

    Topics: Carbon; Carcinoma, Hepatocellular; Cohort Studies; Diet; Eating; Folic Acid; Humans; Liver Neoplasms; Methionine; Nutrients; Prospective Studies; Risk Factors

2022
A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response.
    Stem cell research & therapy, 2022, 07-15, Volume: 13, Issue:1

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Self Renewal; Chemoembolization, Therapeutic; Cholangiocarcinoma; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase

2022
Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Choline; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fibrosis; Interleukin-8; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2023
Metabolic impact of partial hepatectomy in the non-alcoholic steatohepatitis animal model of methionine-choline deficient diet.
    Journal of pharmaceutical and biomedical analysis, 2020, Jan-30, Volume: 178

    Topics: Animals; Choline; Diet; Disease Models, Animal; Hepatectomy; Lipid Metabolism; Liver; Liver Neoplasms; Male; Metabolomics; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2020
One-carbon metabolism-related micronutrients intake and risk for hepatocellular carcinoma: A prospective cohort study.
    International journal of cancer, 2020, 10-15, Volume: 147, Issue:8

    Topics: Carbon; Carcinoma, Hepatocellular; Diet; Dietary Supplements; Eating; Female; Folic Acid; Humans; Liver Neoplasms; Male; Methionine; Micronutrients; Middle Aged; Nutritional Status; Prospective Studies; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2020
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer.
    Nature communications, 2020, 08-07, Volume: 11, Issue:1

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cysteine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 4; Liver; Liver Neoplasms; Mesoderm; Metabolic Networks and Pathways; Metabolome; Methionine; Mice; Sorafenib; Transcription, Genetic

2020
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
    Cell death & disease, 2020, 10-11, Volume: 11, Issue:10

    Topics: Amino Acid Transport Systems; Animals; Calcium-Binding Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cellular Senescence; Coordination Complexes; Copper; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Telomerase; Transfection; Xenograft Model Antitumor Assays

2020
Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells.
    Cells, 2020, 11-16, Volume: 9, Issue:11

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Cell Proliferation; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Mitochondria; Signal Transduction; TOR Serine-Threonine Kinases

2020
Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease.
    Lipids in health and disease, 2020, Dec-09, Volume: 19, Issue:1

    Topics: alpha-Fetoproteins; Animal Feed; Animals; Carcinoma, Hepatocellular; Ceramides; Choline; Choline Deficiency; Diethylnitrosamine; Disease Models, Animal; Humans; Lipidomics; Lipids; Lipogenesis; Liver; Liver Cirrhosis; Liver Neoplasms; Lysophosphatidylcholines; Male; Mass Spectrometry; Methionine; Mice; Mice, Inbred C3H; Non-alcoholic Fatty Liver Disease; Oxidative Stress

2020
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
    Nature communications, 2021, 03-05, Volume: 12, Issue:1

    Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Line, Tumor; CRISPR-Cas Systems; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylmethionine; T-Lymphocytes; Transcriptome

2021
Higher dietary intakes of choline and betaine are associated with a lower risk of primary liver cancer: a case-control study.
    Scientific reports, 2017, 04-06, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Case-Control Studies; China; Choline; Diet; Female; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Odds Ratio; Population Surveillance; Risk Assessment; Risk Factors; Young Adult

2017
Alendronate and FTI-277 combination as a possible therapeutic approach for hepatocellular carcinoma: An in vitro study.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2018, Volume: 17, Issue:3

    Topics: Alendronate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methionine; Proteomics; Signal Transduction; Tandem Mass Spectrometry; Time Factors

2018
Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis.
    Journal of hepatology, 2018, Volume: 69, Issue:3

    Topics: Alkylating Agents; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Gene Silencing; Lipotropic Agents; Liver Neoplasms; Methionine; NF-E2-Related Factor 2; Rats; Treatment Outcome

2018
Metabolism of radiolabeled methionine in hepatocellular carcinoma.
    Molecular imaging and biology, 2014, Volume: 16, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cycloheximide; Hepatocytes; Liver Neoplasms; Marmota; Methionine; Protein Biosynthesis; Radionuclide Imaging; Radiopharmaceuticals; Rats; Solubility; Tritium; Water

2014
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; Drug Therapy, Combination; End Stage Liver Disease; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Neoplasms; Liver Transplantation; Male; Methionine; Middle Aged; Mutation; Retrospective Studies; Risk Factors; Secondary Prevention; Sex Factors; Tyrosine

2014
Attenuation of steatohepatitis, fibrosis, and carcinogenesis in mice fed a methionine-choline deficient diet by CCAAT/enhancer-binding protein homologous protein deficiency.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5

    Topics: Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Choline Deficiency; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice, Inbred C57BL; Middle Aged; Molecular Targeted Therapy

2014
In vitro characterization of uptake mechanism of L-[methyl-(3)H]-methionine in hepatocellular carcinoma.
    Molecular imaging and biology, 2014, Volume: 16, Issue:4

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Cell Survival; Liver Neoplasms; Methionine; Mice; Phosphatidylethanolamine N-Methyltransferase; Radionuclide Imaging; S-Adenosylmethionine; Transfection

2014
Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
    International journal of molecular sciences, 2014, Apr-04, Volume: 15, Issue:4

    Topics: Acetyltransferases; Animals; Carcinoma, Hepatocellular; Choline; Diet; Diethylnitrosamine; Disease Models, Animal; Fatty Acid Elongases; Fatty Acids; Humans; Inflammation; Liver Neoplasms; Methionine; Mice; Mice, Inbred DBA; Mice, Obese; Non-alcoholic Fatty Liver Disease; RNA, Messenger

2014
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:4

    Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Choline; Creatine; Female; Humans; Ketoglutaric Acids; Liver Neoplasms; Male; Methionine; Middle Aged; Niacinamide; Phenotype; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Young Adult

2014
NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
    Nature, 2016, Mar-10, Volume: 531, Issue:7593

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Case-Control Studies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Choline; Diet; Disease Models, Animal; Genes, myc; Hepatocytes; Humans; Linoleic Acid; Lipid Metabolism; Liver; Liver Neoplasms; Male; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Reactive Oxygen Species

2016
Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes.
    Molecular and cellular biochemistry, 2017, Volume: 428, Issue:1-2

    Topics: Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Choline; Diet, High-Fat; Disease Models, Animal; Hep G2 Cells; Hepatic Stellate Cells; Humans; Liver Neoplasms; Male; Methionine; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; RAW 264.7 Cells; Tubulin; Up-Regulation

2017
Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.
    Cell cycle (Georgetown, Tex.), 2008, Volume: 7, Issue:20

    Topics: Animals; Carcinoma, Hepatocellular; Diet; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Methionine; Methylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Random Allocation; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Transforming Growth Factor beta

2008
Correlation of the level of hepatic riboflavin with the appearance of liver tumors in rats fed aminoazo dyes.
    The Journal of experimental medicine, 1948, Volume: 88, Issue:1

    Topics: Animals; Carcinogens; Coloring Agents; Diet; Liver Neoplasms; Methionine; Rats; Riboflavin; Vitamin A

1948
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis.
    The Journal of biological chemistry, 2009, Nov-13, Volume: 284, Issue:46

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cells, Cultured; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Fatty Liver; Female; Homocysteine; Liver; Liver Neoplasms; Methionine; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Unfolded Protein Response

2009
Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide.
    BMB reports, 2009, Sep-30, Volume: 42, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; Free Radical Scavengers; Humans; Liver Neoplasms; Methionine; Methionine Sulfoxide Reductases; NADP; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Saccharomyces cerevisiae

2009
Comparison of the effects on lipid metabolism of dietary methionine and cystine between hepatoma-bearing and normal rats.
    Bioscience, biotechnology, and biochemistry, 2010, Volume: 74, Issue:1

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Cystine; Diet; Eating; Hypolipidemic Agents; Lipid Metabolism; Lipids; Lipolysis; Liver Neoplasms; Male; Methionine; Rats

2010
Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies.
    Journal of chromatography. A, 2010, May-07, Volume: 1217, Issue:19

    Topics: Calibration; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, Liquid; Humans; Liver Neoplasms; Methanol; Methionine; Polyamines; Purine-Nucleoside Phosphorylase; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tumor Cells, Cultured

2010
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    The Journal of nutrition, 2011, Volume: 141, Issue:5

    Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine

2011
Amino acid substitutions in the hepatitis C virus core region are associated with postoperative recurrence and survival of patients with HCV genotype 1b-associated hepatocellular carcinoma.
    Annals of surgery, 2011, Volume: 254, Issue:2

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatectomy; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Leucine; Liver; Liver Function Tests; Liver Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Prognosis; RNA, Messenger; Survival Analysis; Viral Core Proteins

2011
Chemopreventive mechanisms of methionine on inhibition of benzo(a)pyrene-DNA adducts formation in human hepatocellular carcinoma HepG2 cells.
    Toxicology letters, 2012, Feb-05, Volume: 208, Issue:3

    Topics: Arginase; Benzo(a)pyrene; Cathepsin B; DNA Adducts; Glutathione Transferase; Guanine Nucleotide Dissociation Inhibitors; Hep G2 Cells; Histamine N-Methyltransferase; Humans; Lactoylglutathione Lyase; Liver Neoplasms; Methionine; Proteomics; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Spermidine Synthase; Superoxide Dismutase

2012
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:2

    Topics: Alternative Splicing; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Creatinine; Humans; Imidazolidines; Liver Neoplasms; Methionine

2012
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine.
    The Journal of biological chemistry, 2003, May-30, Volume: 278, Issue:22

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; RNA, Messenger; S-Adenosylmethionine; Tumor Cells, Cultured

2003
A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.
    Biochemistry, 2003, May-13, Volume: 42, Issue:18

    Topics: Acetylglucosaminidase; Amino Acid Substitution; Aminopeptidases; Animals; Blotting, Western; Carcinoma, Hepatocellular; DNA Primers; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Glutathione Transferase; Glycoproteins; Glycosylation; Green Fluorescent Proteins; Liver Neoplasms; Luminescent Proteins; Methionine; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Precipitin Tests; Protein Conformation; Rats; Recombinant Fusion Proteins; Serine; Threonine; Tumor Cells, Cultured

2003
Monofunctional platinum complexes showing potent cytotoxicity against human liver carcinoma cell line BEL-7402.
    Journal of medicinal chemistry, 2003, Jul-31, Volume: 46, Issue:16

    Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Methionine; Organoplatinum Compounds; Structure-Activity Relationship; Tumor Cells, Cultured

2003
[The activation of methionine for transmethylation in regenerating rat liver and hepatoma].
    Zeitschrift fur Krebsforschung, 1958, Volume: 62, Issue:4

    Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Rats

1958
METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION.
    Cancer research, 1964, Volume: 24

    Topics: Adrenalectomy; Carbon Isotopes; Carcinoma, Hepatocellular; Cortisone; Hypophysectomy; Liver; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; Oxygenases; Phenylalanine; Portacaval Shunt, Surgical; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tryptophan; Tryptophan Oxygenase

1964
RELATION BETWEEN EXPERIMENTAL HEPATOCARCINOGENESIS AND CIRRHOSIS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Amino Alcohols; Carcinogens; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver Cirrhosis; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Research; Toxicology

1964
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
    Advances in enzyme regulation, 1963, Volume: 1

    Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; Liver; Liver Neoplasms; Methionine; Methylcholanthrene; Microsomes; Microsomes, Liver; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Polycyclic Compounds; Rats; Research; Zoxazolamine

1963
ETHIONINE CARCINOGENESIS IN THE RAT.
    The Journal of pathology and bacteriology, 1965, Volume: 89

    Topics: Carbon Isotopes; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Ethionine; Glycine; Liver; Liver Neoplasms; Methionine; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; RNA; RNA, Neoplasm; Toxicology

1965
[Synthesis of methionine in presence of homogenates of liver of rats treated with 4-dimethylaminoazobenzene].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Dec-31, Volume: 35

    Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; p-Dimethylaminoazobenzene; Rats

1959
Prevention by methionine of dichloroacetic acid-induced liver cancer and DNA hypomethylation in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 77, Issue:2

    Topics: Adenoma, Liver Cell; Animals; Chlorine; Dichloroacetic Acid; DNA Methylation; Drug Combinations; Female; Glycogen; Hepatocytes; Liver Neoplasms; Methionine; Mice; Mice, Inbred Strains; Organ Size; Peroxisome Proliferators; Peroxisomes; Water Purification

2004
Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.
    Proteomics, 2005, Volume: 5, Issue:18

    Topics: Animals; Apolipoprotein A-I; Carcinoma, Hepatocellular; Chromatography, Liquid; Hepatitis B; Humans; Liver Diseases; Liver Neoplasms; Mass Spectrometry; Methionine; Mice; Neoplasm Proteins; Oxidation-Reduction; Protein Isoforms; Proteome; Tryptophan; Up-Regulation

2005
Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells.
    Cytokine, 2006, Jan-21, Volume: 33, Issue:2

    Topics: Actin Depolymerizing Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoskeletal Proteins; Electron-Transferring Flavoproteins; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Proteins; Gene Expression Profiling; Humans; Interleukin-1; Interleukin-1beta; Interleukin-6; Liver Neoplasms; Membrane Proteins; Methionine; Protein Biosynthesis; Proteins; Sulfur Isotopes; Superoxide Dismutase; Up-Regulation

2006
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Apr-25, Volume: 103, Issue:17

    Topics: Allosteric Regulation; Animals; Carcinoma, Hepatocellular; Cell Line; Cystathionine beta-Synthase; Enzyme Stability; Fatty Liver; Gene Silencing; Humans; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Mice; Mice, Knockout; Oxidation-Reduction; Recombinant Proteins; S-Adenosylmethionine

2006
A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats.
    The Journal of nutrition, 2006, Volume: 136, Issue:6

    Topics: Animals; Choline Deficiency; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Folic Acid Deficiency; Gene Silencing; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Inbred F344; Transcription Factors

2006
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas.
    Journal of cellular biochemistry, 2006, Oct-15, Volume: 99, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Diet; Folic Acid Deficiency; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methionine; Microarray Analysis; MicroRNAs; Rats; Rats, Inbred F344

2006
Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.
    International journal of cancer, 2007, Dec-01, Volume: 121, Issue:11

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; DNA Methylation; DNA, Neoplasm; Genes, myc; Genomic Instability; Humans; Immunoblotting; Liver; Liver Neoplasms; Methionine; Mice; Mice, Transgenic; Prognosis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Transforming Growth Factor alpha

2007
Usefulness of 11C-methionine for differentiating tumors from granulomas in experimental rat models: a comparison with 18F-FDG and 18F-FLT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Diagnosis, Differential; Dideoxynucleosides; Fluorodeoxyglucose F18; Granuloma; Inflammation; Liver Neoplasms; Male; Methionine; Mycobacterium bovis; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Turpentine

2008
The effects of casein and methionine on the retention of hepatic riboflavin and on the development of liver tumors in rats fed certain azo dyes.
    Cancer research, 1949, Volume: 9, Issue:2

    Topics: Animals; Azo Compounds; Caseins; Coloring Agents; Liver Neoplasms; Methionine; Organic Chemicals; Rats; Riboflavin

1949
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Glycine N-Methyltransferase; Histones; Janus Kinases; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Mice; Mice, Knockout; Promoter Regions, Genetic; ras Proteins; S-Adenosylmethionine; Signal Transduction; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Transaminases; Tumor Suppressor Proteins

2008
Scintigrams in the diagnosis of hepatic neoplasia. Use of colloidal radioactive gold and of 75-selenium-methionine.
    The American journal of digestive diseases, 1967, Volume: 12, Issue:5

    Topics: Gold Colloid, Radioactive; Humans; Liver Function Tests; Liver Neoplasms; Methionine; Neoplasm Metastasis; Pancreatic Neoplasms; Radiography; Radionuclide Imaging; Selenium

1967
Characterization of nascent and secreted thyroxine-binding globulin in cultured human hepatoma (Hep G2) cells.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Weight; Protein Biosynthesis; Sulfur Radioisotopes; Thyroxine-Binding Proteins

1984
Infusion of branched chain amino acids after partial hepatectomy in man.
    Nutrition and cancer, 1984, Volume: 6, Issue:1

    Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Carcinoma, Hepatocellular; Female; Hepatectomy; Humans; Infusions, Parenteral; Kinetics; Liver Diseases; Liver Neoplasms; Male; Methionine; Middle Aged; Phenylalanine; Tyrosine

1984
Regulation of rat alpha-fetoprotein production by methionine during ethionine-hepatocarcinogenesis.
    International journal of cancer, 1982, Feb-15, Volume: 29, Issue:2

    Topics: alpha-Fetoproteins; Animals; Diet; Ethionine; Female; Liver Neoplasms; Methionine; Rats; Rats, Inbred Strains; Time Factors

1982
Dexamethasone regulates the program of secretory glycoprotein synthesis in hepatoma tissue culture cells.
    The Journal of cell biology, 1980, Volume: 85, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dexamethasone; Fucose; Glycoproteins; Liver; Liver Neoplasms; Membrane Proteins; Methionine; Molecular Weight; Rats

1980
Impaired metabolism of methionine in severe liver diseases. I. Clinical and pathophysiological significance of elevated serum methionine levels.
    Gastroenterologia Japonica, 1982, Volume: 17, Issue:2

    Topics: Amino Acids; Carcinoma, Hepatocellular; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Prognosis

1982
In vitro effects of antitumor antibody--chemotactic factor complexes.
    Clinical immunology and immunopathology, 1982, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Neoplasm; Carbodiimides; Carcinoma, Hepatocellular; Chemotactic Factors; Cytotoxicity, Immunologic; Female; Guinea Pigs; Immunoglobulin G; Interleukin-8; Liver Neoplasms; Macrophages; Male; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neoplasms, Experimental; Oligopeptides; Rabbits

1982
Fibronectin synthesized by a human hepatoma cell line.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Line; Fibronectins; Fluorescent Antibody Technique; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoelectrophoresis, Two-Dimensional; Liver Neoplasms; Methionine; Sulfur Radioisotopes

1984
Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine.
    Cancer letters, 1984, Volume: 24, Issue:3

    Topics: Animals; Cell Nucleus; Choline Deficiency; Free Radicals; Lipid Peroxides; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Inbred F344

1984
Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet.
    The Biochemical journal, 1984, Mar-15, Volume: 218, Issue:3

    Topics: Animals; Cell Nucleus; Choline Deficiency; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine

1984
Influence of dietary lipotrope and lipid content on aflatoxin B1, N-2-fluorenylacetamide, and 1,2-dimethylhydrazine carcinogenesis in rats.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Choline; Choline Deficiency; Diet; Dietary Fats; Dimethylhydrazines; Gastrointestinal Neoplasms; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methionine; Neoplasms, Experimental; Rats

1980
Human hepatoma cell mutant defective in cell surface protein trafficking.
    The Journal of biological chemistry, 1995, Jul-07, Volume: 270, Issue:27

    Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Biological Transport; Carcinoma, Hepatocellular; Cell Compartmentation; Drug Resistance; Endocytosis; Endosomes; Gene Expression; Humans; Liver Neoplasms; Methionine; Mutation; Orosomucoid; Phenotype; Plant Proteins; Protein Processing, Post-Translational; Receptors, Cell Surface; Ribosome Inactivating Proteins, Type 1; Selection, Genetic; Tumor Cells, Cultured

1995
Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes.
    British journal of cancer, 1995, Volume: 71, Issue:4

    Topics: Amino Acid Sequence; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Cisplatin; Clone Cells; Cytosol; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Humans; KB Cells; Liver Neoplasms; Methionine; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured

1995
Levels of amino acids in human hepatocellular carcinoma and adjacent liver tissue.
    Nutrition and cancer, 1995, Volume: 23, Issue:1

    Topics: Aged; Amino Acids; Carcinoma, Hepatocellular; Cystine; Glycine; Humans; Liver; Liver Neoplasms; Methionine; Middle Aged

1995
Characterization of glutathione efflux from Hep G2 cells.
    Research communications in molecular pathology and pharmacology, 1994, Volume: 85, Issue:3

    Topics: Adenosine Triphosphatases; Carcinoma, Hepatocellular; Cell Line; Epidermal Growth Factor; Glutathione; Humans; Insulin; Liver Neoplasms; Methionine; Potassium Channels; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured

1994
The modulation of apolipoprotein E gene expression by 3,3'-5-triiodothyronine in HepG2 cells occurs at transcriptional and post-transcriptional levels.
    European journal of biochemistry, 1994, Sep-01, Volume: 224, Issue:2

    Topics: Apolipoproteins E; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cycloheximide; Gene Expression Regulation; Humans; Kinetics; Liver Neoplasms; Methionine; Orosomucoid; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured

1994
Biogenesis of the hepatitis B viral middle (M) surface protein in a human hepatoma cell line: demonstration of an alternative secretion pathway.
    The Journal of general virology, 1994, Volume: 75 ( Pt 11)

    Topics: Autoradiography; Base Sequence; Brefeldin A; Carcinoma, Hepatocellular; Cell Line; Codon; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glycosylation; Hepatitis B; Hepatitis B virus; Humans; Kinetics; Liver Neoplasms; Methionine; Mutagenesis; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Viral; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured; Viral Envelope Proteins; Virion

1994
Assembly pathway of avian infectious laryngotracheitis virus.
    American journal of veterinary research, 1993, Volume: 54, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Chickens; DNA, Viral; Herpesvirus 2, Gallid; Liver Neoplasms; Marek Disease; Methionine; Microscopy, Electron; Morphogenesis; Thymidine; Tumor Cells, Cultured; Viral Proteins

1993
Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes.
    Biochemical pharmacology, 1994, Mar-02, Volume: 47, Issue:5

    Topics: Adenosine Triphosphate; Amino Acids, Sulfur; Animals; Cell Count; Cysteine; Cystine; Glutathione; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Tumor Cells, Cultured

1994
Retrovirus-mediated gene transfer of transthyretin and transthyretin-methionine 30: a potential tool for the study of amyloidogenesis.
    Neuromuscular disorders : NMD, 1993, Volume: 3, Issue:4

    Topics: 3T3 Cells; Amyloid; Amyloidosis; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line; DNA; Gene Transfer Techniques; Genetic Vectors; Humans; Liver Neoplasms; Methionine; Mice; Molecular Sequence Data; Molecular Weight; Moloney murine leukemia virus; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Polymerase Chain Reaction; Prealbumin; Rats; Repetitive Sequences, Nucleic Acid; Retroviridae; Tumor Cells, Cultured

1993
Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Amino Acid Sequence; Animals; Apolipoprotein B-100; Apolipoproteins B; Base Sequence; Cell Line; Codon; DNA Primers; DNA, Complementary; Humans; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Rats; Restriction Mapping; Sequence Deletion; Sulfur Radioisotopes; Tumor Cells, Cultured

1994
Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.
    Circulatory shock, 1993, Volume: 40, Issue:3

    Topics: Carcinoma, Hepatocellular; Gene Expression; Heat-Shock Proteins; Hot Temperature; Humans; Kinetics; Liver Neoplasms; Methionine; RNA, Messenger; Sulfur Radioisotopes; Tumor Cells, Cultured

1993
The secretory pathway is normal in dithiothreitol-treated cells, but disulfide-bonded proteins are reduced and reversibly retained in the endoplasmic reticulum.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: alpha 1-Antitrypsin; Asialoglycoprotein Receptor; Asialoglycoproteins; Autoradiography; Calcimycin; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cysteine; Disulfides; Dithiothreitol; Endoplasmic Reticulum; Humans; Liver Neoplasms; Macromolecular Substances; Methionine; Neoplasm Proteins; Oxidation-Reduction; Receptors, Immunologic; Ribonucleases; Serum Albumin; Subcellular Fractions; Sulfur Radioisotopes; Transferrin; Tumor Cells, Cultured

1993
Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Amino Acid Sequence; Animals; Choline; DNA; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, myc; Genes, ras; Liver; Liver Neoplasms; Male; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Transfer; Vitamin B 12

1993
Biogenesis of the covalently flavinylated mitochondrial enzyme dimethylglycine dehydrogenase.
    The Journal of biological chemistry, 1996, Apr-19, Volume: 271, Issue:16

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Dimethylglycine Dehydrogenase; Flavin-Adenine Dinucleotide; Gene Expression; Hepatoblastoma; Humans; Kinetics; Liver Neoplasms; Methionine; Mitochondria, Liver; Mitochondrial Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidoreductases, N-Demethylating; Protein Biosynthesis; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured

1996
Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells.
    Biochemical and biophysical research communications, 1996, Sep-24, Volume: 226, Issue:3

    Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Humans; Immunoglobulin G; Kinetics; Liver Neoplasms; Methionine; Microsomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1996
Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets.
    Free radical biology & medicine, 1997, Volume: 23, Issue:6

    Topics: Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Heme Oxygenase (Decyclizing); Liver Neoplasms; Male; Methionine; Niacin; Oxidative Stress; Rats; Rats, Inbred F344; Vitamin A; Vitamin E; Vitamin E Deficiency; Vitamins; Weight Gain

1997
Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.
    Journal of lipid research, 1998, Volume: 39, Issue:7

    Topics: Affinity Labels; Animals; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Cattle; Cells, Cultured; Cysteine; Humans; Indoles; Isoindoles; Kinetics; Liver; Liver Neoplasms; Methionine; Microsomes; Microsomes, Liver; Piperidines; Rats; Sulfur Radioisotopes; Triglycerides; Tumor Cells, Cultured; Ultraviolet Rays

1998
Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma.
    Cancer letters, 1999, Feb-08, Volume: 136, Issue:1

    Topics: Arginine; Blotting, Southern; Carcinoma, Hepatocellular; DNA, Neoplasm; Glycine; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Mutation; Threonine

1999
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Carcinoma, Hepatocellular; Enzymes; Humans; Isoenzymes; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; RNA, Messenger

2000
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:1

    Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12

1975
Cytologic changes induced in rat livers cells by short-term exposure to chemical substances.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:5

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Butanes; Carcinogens; Chromosome Aberrations; DDT; Diethylnitrosamine; Diploidy; Hepatectomy; Hexachlorocyclohexane; Hydrazines; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Mitosis; Nitroso Compounds; Rats

1975
[Achievements and perspectives of radioisotope diagnosis of malignant tumors (according to materials in the "Journal of Nuclear Medicine", 1974)].
    Meditsinskaia radiologiia, 1976, Volume: 21, Issue:1

    Topics: Actinoid Series Elements; Animals; Antigens, Neoplasm; Bleomycin; Breast Neoplasms; Female; Gallium Radioisotopes; Humans; Indium; Iodine Radioisotopes; Isotope Labeling; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Metals, Rare Earth; Methionine; Mice; Neoplasms; Radioisotopes; Radionuclide Imaging; Selenium; Technetium; Ytterbium

1976
Reduction of N-nitrosodiethylamine carcinogenesis in rats by lipotrope or amino acid supplementation of a marginally deficient diet.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Amino Acids; Animals; Body Weight; Carcinoma, Hepatocellular; Choline; Diet; Dietary Fats; Diethylnitrosamine; Esophageal Neoplasms; Folic Acid; Hemangioendothelioma; Lipotropic Agents; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Nicotinic Acids; Nitrosamines; Rats

1977
S-adenosylmethionine:protein methyltransferases in hepatomas.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Adenine; Animals; Arginine; Carcinoma, Hepatocellular; Cell Nucleus; Cytosol; Histones; Liver; Liver Neoplasms; Lysine; Methionine; Methyltransferases; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Rats; Sulfuric Acids

1975
[Diagnosis of primary hepatocellular carcinoma with 99mTc-acetylmethyonine].
    Kaku igaku. The Japanese journal of nuclear medicine, 1975, Volume: 12, Issue:1

    Topics: Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Radionuclide Imaging; Technetium

1975
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
    Nucleic acids research, 1975, Volume: 2, Issue:6

    Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine

1975
Partial purification and characterization of tumor and liver S-adenosylmethionine synthetases.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Female; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Neoplasms, Experimental; Phosphates; Rats; Transferases; tRNA Methyltransferases

1977
Labeling of hepatitis B virus surface antigen (HBsAg) synthesized in a HBsAg-producing hepatoma cell line.
    Journal of medical virology, 1979, Volume: 4, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Cystine; Cytoplasm; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methionine; Molecular Weight; Peptides; Sulfur Radioisotopes

1979
Specificity of the glutamine-binding site involved in the reguation of glutamine-synthetase activity in hepatoma tissue-culture cells.
    European journal of biochemistry, 1975, Aug-15, Volume: 56, Issue:2

    Topics: Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Diazooxonorleucine; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Methionine; Neoplasms, Experimental; Sulfones

1975
The influence of DL-methionine on the metabolism of S-adenosylethionine in rats chronically treated with DL-ethionine.
    Cancer research, 1976, Volume: 36, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Body Weight; Circadian Rhythm; Ethionine; Feeding Behavior; Female; Liver; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

1976
Mechanism of suppressive effect of basic cupric acetate on rat liver carcinogenesis by ethionine.
    Gan, 1976, Volume: 67, Issue:2

    Topics: Adenosine; Alkylation; Animals; Copper; Drug Interactions; Ethionine; Liver; Liver Neoplasms; Male; Methionine; Microsomes, Liver; Neoplasms, Experimental; Rats; RNA, Transfer

1976
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
    Cancer research, 1975, Volume: 35, Issue:4

    Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms

1975
The effect of ethionine on ribonucleic acid synthesis in rat liver.
    The Biochemical journal, 1975, Volume: 150, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cycloheximide; Ethionine; Female; HeLa Cells; Inosine; Liver; Liver Neoplasms; Methionine; Methylation; Mitoguazone; Rats; RNA; RNA, Ribosomal; RNA, Transfer; S-Adenosylmethionine

1975
A comparison of the ability of normal liver, a premalignant liver, a solid hepatoma and the Zajdela ascitic hepatoma, to take up amino acids in vitro.
    The Journal of membrane biology, 1976, Feb-17, Volume: 26, Issue:1

    Topics: Amino Acids; Animals; Arginine; In Vitro Techniques; Kinetics; Leucine; Liver; Liver Neoplasms; Lysine; Methionine; Phenylalanine; Precancerous Conditions; Valine

1976
The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins.
    The Journal of biological chemistry, 1992, May-15, Volume: 267, Issue:14

    Topics: Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Humans; Kinetics; Lipoproteins; Liver Neoplasms; Methionine; Protein Biosynthesis; Sulfur Radioisotopes; Transfection

1992
Identification of subcellular compartments involved in biosynthetic processing of cathepsin D.
    The Journal of biological chemistry, 1992, Aug-05, Volume: 267, Issue:22

    Topics: alpha 1-Antitrypsin; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Golgi Apparatus; Horseradish Peroxidase; Humans; Kinetics; Liver Neoplasms; Methionine; Protein Processing, Post-Translational; Subcellular Fractions; Sulfur Radioisotopes

1992
The effects of vitamin K1 and warfarin on prothrombin expression in human hepatoblastoma (HepG2) cells.
    Thrombosis and haemostasis, 1992, Jul-06, Volume: 68, Issue:1

    Topics: Antigens; Blotting, Northern; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methionine; Nucleic Acid Hybridization; Precipitin Tests; Prothrombin; RNA, Messenger; Sulfur Radioisotopes; Transcription, Genetic; Tumor Cells, Cultured; Vitamin K 1; Warfarin

1992
Liver DNA adducts in methyl-deficient rats administered a single dose of aflatoxin B1.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biotransformation; Choline Deficiency; Diet; DNA; DNA Repair; Liver; Liver Neoplasms; Liver Regeneration; Male; Methionine; Precancerous Conditions; Rats; Rats, Inbred F344

1992
NF-AB, a liver-specific and cytokine-inducible nuclear factor that interacts with the interleukin-1 response element of the rat alpha 1-acid glycoprotein gene.
    Molecular and cellular biology, 1991, Volume: 11, Issue:6

    Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cytokines; Dexamethasone; Genes; Humans; Interleukin-1; Interleukin-6; Kidney; Kinetics; Liver; Liver Neoplasms; Methionine; Molecular Weight; Nuclear Proteins; Orosomucoid; Protein Binding; Rats; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Transfection

1991
Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetophenones; Carcinoma, Hepatocellular; Cell Survival; Chromatography, Gel; Cycloheximide; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Hydrolysis; Isoflurophate; L-Lactate Dehydrogenase; Liver Neoplasms; Methionine; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Precipitin Tests; Tumor Cells, Cultured

1991
Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells.
    European journal of biochemistry, 1991, Feb-14, Volume: 195, Issue:3

    Topics: Amino Acid Sequence; Autoradiography; Butyrates; Butyric Acid; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Humans; Kinetics; Liver Neoplasms; Methionine; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Sulfur Radioisotopes

1991
[35S]methionine interaction with rat liver tRNA and effect of chemical carcinogens.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA; Ethionine; Hepatectomy; Liver; Liver Neoplasms; Male; Methionine; Methylnitrosourea; Rats; Rats, Inbred Strains; Reference Values; RNA, Transfer; Sulfur Radioisotopes; Tissue Distribution

1991
Enhanced expression of a 27 kD protein during diethylnitrosamine-induced hepatocarcinogenesis in rats.
    Biochemical and biophysical research communications, 1990, Jul-31, Volume: 170, Issue:2

    Topics: Animals; Cadmium; Diethylnitrosamine; Female; Fluorescence; Heat-Shock Proteins; Liver Neoplasms; Methionine; Molecular Weight; Neoplasm Proteins; Rats; Rats, Inbred Strains

1990
Bromoconduritol treatment delays intracellular transport of secretory glycoproteins in human hepatoma cell cultures.
    Biochemical and biophysical research communications, 1989, Jun-30, Volume: 161, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Cyclohexenes; Glucosidases; Glycoproteins; Humans; Inositol; Kinetics; Liver Neoplasms; Methionine; Neoplasm Proteins; Protein Processing, Post-Translational; Tumor Cells, Cultured

1989
3-Aminobenzamide inhibits poly(ADP ribose) synthetase activity and induces phosphoenolpyruvate carboxykinase (GTP) in H4IIE hepatoma cells.
    Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2

    Topics: Adenosine Diphosphate Ribose; Benzamides; Carcinoma, Hepatocellular; Cyclic AMP; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Immunosorbent Techniques; Liver Neoplasms; Methionine; Phosphoenolpyruvate Carboxykinase (GTP); Poly(ADP-ribose) Polymerase Inhibitors; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured

1988
Regulation of apoprotein synthesis and secretion in the human hepatoma Hep G2. The effect of exogenous lipoprotein.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Apolipoproteins E; Apoproteins; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cholesterol; Chylomicrons; Electrophoresis, Polyacrylamide Gel; Fatty Acids, Nonesterified; Immunosorbent Techniques; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Liposomes; Liver Neoplasms; Methionine; Triglycerides; Tumor Cells, Cultured

1988
Synthesis and secretion of protein C inhibitor by the human hepatoma-derived cell line, Hep G2.
    Biochimica et biophysica acta, 1985, Feb-21, Volume: 844, Issue:2

    Topics: Blood Proteins; Carcinoma, Hepatocellular; Cell Line; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Liver Neoplasms; Methionine; Molecular Weight; Protein C Inhibitor

1985
Synthesis and processing of human serum apolipoprotein AII in vitro and in Hep G2 cells.
    Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:2

    Topics: Amino Acid Sequence; Apolipoprotein A-II; Apolipoproteins A; Carcinoma, Hepatocellular; Cell-Free System; Cells, Cultured; Cysteine; Endoplasmic Reticulum; Humans; Liver; Liver Neoplasms; Methionine; Pancreas; Precipitin Tests; Protein Biosynthesis; RNA, Messenger

1985
Pulse-chase studies of the synthesis of apolipoprotein B in a human hepatoma cell line, Hep G2.
    European journal of biochemistry, 1985, Jun-18, Volume: 149, Issue:3

    Topics: Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Humans; Immunochemistry; Liver Neoplasms; Methionine; Molecular Weight; Peptide Biosynthesis; Sulfur Radioisotopes; Time Factors

1985
Biosynthesis of functionally active heparin cofactor II by a human hepatoma-derived cell line.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Antibody Specificity; Carcinoma, Hepatocellular; Cell Line; Dermatan Sulfate; Glycoproteins; Heparin; Heparin Cofactor II; Humans; Immunoelectrophoresis; Liver Neoplasms; Methionine; Molecular Weight; Thrombin

1985
Enhanced phosphatidylinositol kinase activity is associated with early stages of hepatocarcinogenesis and hepatocellular carcinoma.
    Biochemical and biophysical research communications, 1985, Nov-15, Volume: 132, Issue:3

    Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Carcinoma, Hepatocellular; Choline Deficiency; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methionine; Phosphotransferases; Precancerous Conditions; Rats; Rats, Inbred F344

1985
Effect of the antileukemic agent L-asparaginase on thyroxine-binding globulin and albumin synthesis in cultured human hepatoma (HEP G2) cells.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: Asparaginase; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA Replication; Humans; Liver Neoplasms; Methionine; Serum Albumin; Thyroxine-Binding Proteins; Time Factors

1986
Catabolic properties of aglycofibrinogen synthesized by tunicamycin-treated human hepatoma (HepG2) cells and rabbit hepatocytes.
    Biochimica et biophysica acta, 1986, Oct-01, Volume: 883, Issue:3

    Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Fibrinogen; Humans; Hydrolysis; Liver; Liver Neoplasms; Methionine; Oligosaccharides; Rabbits; Tunicamycin

1986
Intracellular modifications of human apolipoprotein E.
    The Journal of biological chemistry, 1986, Oct-15, Volume: 261, Issue:29

    Topics: Apolipoproteins E; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Liver Neoplasms; Macrophages; Methionine; Monensin; Monocytes; Sulfur Radioisotopes

1986
Very low and low density lipoprotein synthesis and secretion by the human hepatoma cell line Hep-G2: effects of free fatty acid.
    Journal of lipid research, 1986, Volume: 27, Issue:8

    Topics: Acetates; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Methionine; Mevalonic Acid; Oleic Acid; Oleic Acids; Phospholipids; Serum Albumin, Bovine; Triglycerides

1986
Lipotropic factors and oncogenesis.
    Advances in experimental medicine and biology, 1986, Volume: 206

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Folic Acid Deficiency; Humans; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Vitamin B 12 Deficiency

1986
Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Animals; Body Weight; Choline; Deoxycytidine; Diet; Diethylnitrosamine; DNA; Liver; Liver Neoplasms; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Organ Size; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors

1986
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Male; Methionine; Phenobarbital; Prohibitins; Rats; Rats, Inbred F344; Weaning

1986
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
    Archives of biochemistry and biophysics, 1974, Volume: 165, Issue:2

    Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine

1974
A lipotrope-dependent increase of histidase and urocanase in the livers of choline-deficient rats and in the Reuber H-35 transplanted hepatoma.
    Biochimica et biophysica acta, 1973, Oct-10, Volume: 321, Issue:2

    Topics: Ammonia-Lyases; Animals; Carcinoma, Hepatocellular; Choline; Choline Deficiency; Diet; Histidine Ammonia-Lyase; Hydro-Lyases; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Time Factors; Urocanate Hydratase; Vitamin B 12

1973
Hepatorenal lesions in rats fed a low lipotrope diet and exposed to aflatoxin.
    The Journal of nutrition, 1968, Volume: 94, Issue:3

    Topics: Aflatoxins; Animals; Autoradiography; Body Weight; Choline; Diet; DNA; Hyperplasia; Kidney; Lipids; Lipotropic Agents; Liver; Liver Neoplasms; Male; Methionine; Rats; Thymidine; Tritium; Vitamin B 12

1968
S-adenosylmethionine-synthesizing activity of normal and neoplastic mouse tissues.
    Cancer research, 1966, Volume: 26, Issue:12

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Estrogens; Female; Glucosyltransferases; Liver; Liver Neoplasms; Methionine; Mice; Neoplasms, Experimental; Rabbits; Testosterone

1966
Cystathioninuria.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carcinoma, Hepatocellular; Child, Preschool; Cysteine; Diet Therapy; Female; Galactosemias; Glycogen; Humans; Infant; Intellectual Disability; Liver Neoplasms; Male; Maple Syrup Urine Disease; Methionine; Middle Aged; Neuroblastoma; Phenylketonurias; Portal Vein; Pyridoxine; Serine; Sulfisoxazole; Tyrosine

1967
Utilization of L-methionine and S-adenosyl-L-methionine for methylation of soluble RNA by mouse liver and hepatoma extracts.
    Cancer research, 1967, Volume: 27, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Alkylation; Animals; Bacillus subtilis; Carbon Isotopes; Carcinoma, Hepatocellular; Escherichia coli; Female; Fishes; Liver; Liver Neoplasms; Male; Methionine; Mice; Neoplasms, Experimental; Nucleosides; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Tritium; Yeasts

1967
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides

1968
S-adenosylmethionine synthetase activity in some normal rat tissues and transplantable hepatomas.
    Cancer research, 1968, Volume: 28, Issue:12

    Topics: Adenosine Triphosphate; Animals; Brain; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, Paper; Epididymis; Female; Kidney; Liver; Liver Neoplasms; Male; Methionine; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sex Factors; Spectrum Analysis; Testis; Transferases

1968
Studies on DNA methylase activity in mammalian tissue.
    Experientia, 1969, Apr-15, Volume: 25, Issue:4

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Edetic Acid; Liver; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Quaternary Ammonium Compounds; Salmonidae; Testis; Transferases

1969
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
    Journal of molecular biology, 1969, Jun-14, Volume: 42, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine

1969
The distribution and concentration of 75Se-selenomethionine in man.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1969, Volume: 10, Issue:11

    Topics: Carcinoma, Bronchogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Humans; Liver Neoplasms; Male; Methionine; Radioisotopes; Selenium

1969
Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma.
    Journal of molecular biology, 1969, Volume: 39, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Densitometry; Electrophoresis; Formates; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleotides; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides

1969
Methylation of transfer RNA and of ribosomal RNA in rat liver in the intact animal and the effect of carcinogens.
    Biochimica et biophysica acta, 1969, Dec-16, Volume: 195, Issue:2

    Topics: Aflatoxins; Animals; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Paper; Ethionine; Female; Intestine, Small; Kinetics; Liver; Liver Neoplasms; Male; Methionine; Methylation; Models, Biological; Models, Chemical; Nitrosamines; Nucleotides; Perchlorates; Precancerous Conditions; Protein Biosynthesis; Purinones; Rats; Ribosomes; RNA; RNA, Neoplasm; RNA, Transfer; Stimulation, Chemical; Time Factors

1969
Natural inhibitors of the transfer ribonucleic acid methylases.
    Biochemistry, 1970, Feb-03, Volume: 9, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Dialysis; Drug Stability; Escherichia coli; Female; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Omentum; Pregnancy; Quaternary Ammonium Compounds; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Trypsin; Ultracentrifugation

1970
Development of resistance of Novikoff hepatoma to 5-fluoro-2'-deoxyuridine.
    International journal of cancer, 1970, Sep-15, Volume: 6, Issue:2

    Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Floxuridine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Thymidine; Thymine; Tritium

1970
Methylation of preribosomal and transfer RNA's by isolated nucleoli of the Novikoff rat tumor.
    Biochimica et biophysica acta, 1970, Nov-12, Volume: 224, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Transfer; Tritium

1970
75se-selenomethionine in the scintiscan diignosis of primary hepatocellular carcinoma.
    Gut, 1971, Volume: 12, Issue:4

    Topics: Adenoma, Bile Duct; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methionine; Neoplasm Metastasis; Radionuclide Imaging; Selenium

1971
Methylation of mammalian deoxyribonucleic acid. II. The distribution of 5-methylcytosine in pyrimidine deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1971, Aug-10, Volume: 246, Issue:15

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Techniques; Cytosine; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA, Neoplasm; Formates; Hydrolysis; Liver Neoplasms; Methionine; Methods; Methylation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; Snakes; Spectrophotometry; Thymine Nucleotides; Venoms

1971
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
    Biochimica et biophysica acta, 1971, May-13, Volume: 238, Issue:2

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors

1971
Diagnosis of hepatoma using a multiple radionuclide approach.
    Radiology, 1972, Volume: 102, Issue:2

    Topics: Angiography; Biopsy; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Male; Methionine; Methods; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium; Serum Albumin, Radio-Iodinated; Technetium

1972
Transfer ribonucleic acid methylases of nucleoli isolated from a rat tumor.
    Biochemistry, 1972, Feb-15, Volume: 11, Issue:4

    Topics: Ammonium Chloride; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Escherichia coli; Kinetics; Liver Neoplasms; Magnesium; Methionine; Methyltransferases; Neoplasms, Experimental; Osmolar Concentration; Polynucleotides; Rats; RNA, Transfer; S-Adenosylmethionine; Structure-Activity Relationship; Subcellular Fractions; Tritium

1972
Methylation patterns of transfer RNA from ascites hepatomas.
    Biochimica et biophysica acta, 1972, Jan-18, Volume: 259, Issue:1

    Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine Nucleotides; Guanine Nucleotides; Inosine Nucleotides; Liver; Liver Neoplasms; Methionine; Methylation; Nucleotides; Rats; RNA, Transfer; Tritium; Uracil Nucleotides

1972
Methylation of mammalian deoxyribonucleic acid. 3. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1972, May-10, Volume: 247, Issue:9

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Clone Cells; Cytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Escherichia coli; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats; Spleen; Venoms

1972
Action of ethionine, methionine, ATP, adenine, albumin and Ca 2+ on protein synthesis of normal and tumor cells.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Albumins; Amino Acids; Analysis of Variance; Animals; Calcium; Carbon Isotopes; Carcinoma, Hepatocellular; Cells; Edetic Acid; Ethionine; Female; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Methionine; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Rats; Rats, Inbred Strains

1972
Uptake of 75 Se-selenomethionine by hepatoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1972, Volume: 13, Issue:7

    Topics: Aged; Carcinoma, Hepatocellular; Colloids; Female; Humans; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Sulfur; Technetium

1972
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency

1972
Hepatocellular carcinoma. Clinical and laboratory observations.
    The American journal of gastroenterology, 1972, Volume: 58, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Blood Protein Electrophoresis; Carcinoma, Hepatocellular; Colloids; Fetal Proteins; Humans; Immunodiffusion; Iodine Radioisotopes; Liver Neoplasms; Male; Methionine; Middle Aged; Radionuclide Imaging; Rose Bengal; Selenium; Sulfur Isotopes; Technetium

1972
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen

1972
[Double hepatic scintigraphy (gold-selenomethionine) in the diagnosis of primary tumors of the liver].
    Medecine & chirurgie digestives, 1972, Volume: 1, Issue:6

    Topics: Carcinoma, Hepatocellular; Gold Isotopes; Humans; Liver Neoplasms; Methionine; Methods; Radionuclide Imaging; Selenium

1972
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine

1973
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
    Cancer research, 1973, Volume: 33, Issue:9

    Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12

1973
The radiological and scintigraphic investigation of spontaneous hypoglycaemia.
    Clinical radiology, 1973, Volume: 24, Issue:2

    Topics: Abdominal Neoplasms; Adenoma, Islet Cell; Adult; Female; Fibrosarcoma; Humans; Hypoglycemia; Liver Neoplasms; Male; Methionine; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Prognosis; Radiography; Radioisotopes; Radionuclide Imaging; Retroperitoneal Neoplasms; Selenium; Technetium

1973
[Scintiphotography of primary hepatocellular carcinoma with 75Se-selenomethionine (author's transl)].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1973, Volume: 33, Issue:6

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Radioisotopes; Radionuclide Imaging; Selenium

1973
Studies of initiation factors in protein synthesis of host liver and transplantable hepatoma.
    Cancer research, 1974, Volume: 34, Issue:2

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Methionine; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Poly U; Protein Binding; Rats; Ribosomes; RNA, Ribosomal; RNA, Transfer; Transplantation, Homologous

1974
Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.
    Cancer research, 1974, Volume: 34, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Mercaptopurine; Methionine; Neoplasms, Experimental; Nitriles; Pyrimidines; Pyrroles; Ribonucleosides; RNA, Neoplasm; RNA, Ribosomal; Tritium; Uridine

1974
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
    Biochemistry, 1974, Mar-12, Volume: 13, Issue:6

    Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine

1974
The enzymology of methionine metabolism in rat hepatomas.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Dietary Proteins; Liver; Liver Neoplasms; Male; Methionine; Methyltransferases; Neoplasms, Experimental; Rats; Transferases

1974
Beta-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue.
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Aminoisobutyric Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cytosine; DNA; DNA, Neoplasm; Female; Formates; Hepatectomy; Liver Neoplasms; Liver Regeneration; Methionine; Neoplasms, Experimental; Rats; RNA; RNA, Neoplasm; Thymine; Tritium

1974
[A new method for the isotopic diagnosis of primary hepatomas using selenomethionine].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1973, Volume: 54, Issue:11

    Topics: Carcinoma, Hepatocellular; Colloids; Humans; Liver Neoplasms; Methionine; Methods; Neoplasm Metastasis; Radionuclide Imaging; Selenium; Statistics as Topic; Technetium

1973
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
    Cell differentiation, 1972, Volume: 1, Issue:3

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine

1972
Protein and ribonucleic acid metabolism in single-cell suspensions from Morris hepatoma 5123tc and from normal rat liver.
    Cancer research, 1974, Volume: 34, Issue:9

    Topics: Albumins; Animals; Anti-Bacterial Agents; Calcium; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Kinetics; Leucine; Liver; Liver Neoplasms; Magnesium; Methionine; Mitochondria, Liver; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Potassium; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Transplantation, Homologous

1974
The use of multiple radionuclide imaging to differentiate the focal intrahepatic lesion.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1974, Volume: 121, Issue:4

    Topics: Carcinoma, Hepatocellular; Cysts; Hemangioma; Humans; Indium; Isotopes; Liver Abscess; Liver Circulation; Liver Diseases; Liver Neoplasms; Methionine; Radiography; Radioisotopes; Radionuclide Imaging; Selenium

1974
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
    Gan, 1974, Volume: 65, Issue:6

    Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases

1974
75 Se-selenomethionine in hepatic focal lesions.
    Seminars in nuclear medicine, 1972, Volume: 2, Issue:2

    Topics: Angiography; Carcinoma; Cysts; Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Liver; Liver Abscess; Liver Abscess, Amebic; Liver Diseases; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methionine; Neoplasm Metastasis; Pancreas; Radioisotopes; Radionuclide Imaging; Selenium; Subtraction Technique

1972
[Use of methionine-Se75 for studying metabolic processes in the liver].
    Meditsinskaia radiologiia, 1972, Volume: 17, Issue:12

    Topics: Female; Humans; Liver; Liver Diseases; Liver Neoplasms; Male; Methionine; Radioisotopes; Radionuclide Imaging; Selenium

1972
False-negative 75Se-selenomethionine scans in primary liver cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1974, Volume: 15, Issue:4

    Topics: Colloids; Cysts; False Negative Reactions; Humans; Liver Diseases; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Sulfur; Technetium

1974
Transfer ribonucleic acid methylases in normal tissues and in tumours.
    The Biochemical journal, 1971, Volume: 124, Issue:5

    Topics: Animals; Carbon Isotopes; Chromatography; Escherichia coli; Hepatectomy; Kidney Neoplasms; Liver Neoplasms; Liver Regeneration; Methionine; Methyltransferases; Neoplasms, Experimental; Nitrosamines; RNA, Bacterial; RNA, Transfer

1971
[Specific detection of liver neoplasms using double labelling with selenomethionine-75 and colloidal gold-198].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Jun-21, Volume: 272, Issue:25

    Topics: Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Liver; Liver Diseases; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium

1971
Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine.
    The Biochemical journal, 1972, Volume: 128, Issue:1

    Topics: Animals; Carbon Isotopes; Dactinomycin; Ethionine; Guanine; Liver; Liver Neoplasms; Male; Methionine; Methylation; Pyrimidines; Rats; Ribose; RNA, Bacterial; RNA, Transfer

1972
[Original method of diagnosis of liver neoplasms: radioisotope scanning with selenomethionine].
    Revue medico-chirurgicale des maladies du foie, 1971, Volume: 46, Issue:2

    Topics: Adolescent; Aged; Gold Colloid, Radioactive; Humans; Liver Neoplasms; Male; Methionine; Middle Aged; Radionuclide Imaging; Selenium

1971
Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine.
    The Biochemical journal, 1971, Volume: 123, Issue:2

    Topics: Alkylation; Animals; Carcinogens; Chromatography, Ion Exchange; DNA; Ethionine; Guanine; Hydrolysis; Liver; Liver Neoplasms; Male; Methionine; Rats; Tritium

1971
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.
    The Biochemical journal, 1971, Volume: 124, Issue:4

    Topics: Alkylation; Amino Acids; Animals; Carbon Isotopes; Carcinogens; Chromatography, Ion Exchange; Chromatography, Paper; Female; Formaldehyde; Histones; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Methionine; Methylation; Necrosis; Nitrosamines; Rats; S-Adenosylmethionine; Sulfonic Acids; Tritium

1971
The value of scintiscanning in the diagnosis of hepatic tumours using both selenomethionine and technetium.
    The British journal of radiology, 1970, Volume: 43, Issue:515

    Topics: Humans; Liver Neoplasms; Methionine; Radioisotopes; Radionuclide Imaging; Selenium; Technetium

1970
[Pepper type neuroblastoma with homocystinuria. Diagnosis, biochemistry and therapy].
    Helvetica paediatrica acta, 1970, Volume: 25, Issue:5

    Topics: Amino Acids; Catecholamines; Child, Preschool; Cyclophosphamide; Dopamine; Homocystinuria; Humans; Liver Neoplasms; Male; Methionine; Neoplasm Metastasis; Neuroblastoma; Norepinephrine; Normetanephrine; Phenylacetates; Pyridoxine; Serine; Stereoisomerism; Vanilmandelic Acid; Vincristine

1970
[Probles in the positive cintigraphic diagnosis of abdomina tumors with 75Se-selenit].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1970, Volume: 113, Issue:1

    Topics: Abdominal Neoplasms; Adult; Aged; Diagnosis, Differential; Female; Gallbladder Neoplasms; Gold Isotopes; Hemangioma; Humans; Injections, Intravenous; Liver Neoplasms; Male; Methionine; Methods; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Pancreas; Pancreatic Neoplasms; Radionuclide Imaging; Selenium

1970
Clinical and experimental uses of radioisotopes in the diagnosis of cancer.
    American journal of surgery, 1968, Volume: 115, Issue:5

    Topics: Bone Neoplasms; Brain Neoplasms; Calcium Isotopes; Cesium Isotopes; DNA; Eye Neoplasms; Fluorine; Gallium; Humans; Iodine Radioisotopes; Liver Neoplasms; Methionine; Neoplasms; Phosphorus Isotopes; Radionuclide Imaging; Rubidium; Selenium; Strontium Isotopes; Thyroid Neoplasms

1968
[Scintigraphy of the liver, gallbladder and pancreas].
    Schweizerische medizinische Wochenschrift, 1968, Feb-24, Volume: 98, Issue:8

    Topics: Arteriovenous Fistula; Gallbladder; Humans; Iodine Radioisotopes; Liver; Liver Cirrhosis; Liver Neoplasms; Malabsorption Syndromes; Methionine; Neoplasm Metastasis; Pancreas; Pancreatitis; Radioisotopes; Radionuclide Imaging; Selenium

1968
[In vivo methylation of rat liver RNA and under the influence of diethylnitrosamine].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:12

    Topics: Animals; Carbon Isotopes; Carcinogens; Centrifugation, Zonal; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nitrosamines; Orotic Acid; Rats; Ribosomes; RNA; Tritium

1968
[Quantitative studies on organ distribution following administration of various radioisotopes, using a 10-crystal scanner and computer scintigraphy].
    Strahlentherapie. Sonderbande, 1968, Volume: 67

    Topics: Coloring Agents; Computers; Gold Colloid, Radioactive; Gold Isotopes; Humans; Iodine Radioisotopes; Kidney; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Methods; Neoplasm Metastasis; Pancreas; Radioisotopes; Radionuclide Imaging; Selenium

1968
Starch-gel electrophoresis of human tissue enzymes which hydrolyze L-leucyl-beta-naphthylamide.
    Science (New York, N.Y.), 1966, May-27, Volume: 152, Issue:3726

    Topics: Amides; Amidohydrolases; Breast Neoplasms; Chemical Phenomena; Chemistry; Electrophoresis; Humans; In Vitro Techniques; Leucyl Aminopeptidase; Liver Neoplasms; Methionine; Naphthalenes

1966