methionine has been researched along with Aging in 291 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 90 (30.93) | 18.7374 |
| 1990's | 42 (14.43) | 18.2507 |
| 2000's | 71 (24.40) | 29.6817 |
| 2010's | 72 (24.74) | 24.3611 |
| 2020's | 16 (5.50) | 2.80 |
| Authors | Studies |
|---|---|
| Asara, JM; Binari, R; Filine, E; Jouandin, P; Leshchiner, D; Parkhitko, AA; Perrimon, N; Rabinowitz, JD; Wang, L | 1 |
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| Ayala, V; Cabré, R; Canales, I; Ferrer, I; Galo-Licona, JD; Jové, M; Martin-Garí, M; Mota-Martorell, N; Nogueras, L; Obis, È; Pamplona, R; Portero-Otín, M; Ramos, P; Sol, J; Torres, P | 1 |
| Blackwell, TK; Kanai, M; Kohara, Y; Masumura, K; Mizunuma, M; Ogawa, T; Ohya, Y; Soga, T | 1 |
| Cesanelli, L; Degens, H; Swaminathan, A; Venckunas, T | 1 |
| Le, G; Li, B; Shi, Y; Xie, Y; Xu, Y; Yang, Y | 1 |
| Cuellar, TL; Johnson, AA | 1 |
| Dönertaş, HM; Işıldak, U | 1 |
| Jouandin, P; Mohr, SE; Parkhitko, AA; Perrimon, N | 1 |
| Komninou, D; Malloy, VL; Richie, JP; Sinha, R; Zimmerman, JA | 1 |
| Altenhofen, S; Bonan, CD; Dos Santos, TM; Rubensam, G; Wiprich, MT; Wyse, ATS; Zanandrea, R | 1 |
| Cheng, X; Feng, C; Ge, Y; Han, L; Le, GW; Shi, Y; Sun, J; Tang, X; Wu, G; Yu, Y | 1 |
| Jagodic, M; Kular, L | 1 |
| Acar, MB; Ayaz-Güner, Ş; Di Bernardo, G; Galderisi, U; Güner, H; Murat, A; Özcan, S; Peluso, G | 1 |
| Degens, H; Fokin, A; Swaminathan, A; Venckūnas, T | 1 |
| Chen, S; Fang, AP; He, TT; Hou, MJ; Long, JA; Lu, XT; Luo, Y; Tan, XY; Tang, ZH; Yishake, D; Zhong, RH; Zhu, HL | 1 |
| Moskovitz, J; Smith, A | 1 |
| Cynober, L; Deutz, NE; Engelen, MP; Ligthart-Melis, GC; Simbo, SY; Smriga, M | 1 |
| André Casali, E; Braganhol, E; Couto, CATD; da Silva, TM; Frescura Duarte, M; Gazal, M; Hofstätter Azambuja, J; Maria Spanevello, R; Moritz, CEJ; Moro Stefanello, F; Nogueira Debom, G; Rodrigues, R; Soares, MSP; Zanusso Costa, M | 1 |
| Alves, C; Cardoso, M; Cavaco, S; Coelho, T; Fernandes, J; Kelly, JW; Martins da Silva, A; Monteiro, C; Samões, R | 1 |
| Cant, JP; McKnight, LM; Shoveller, AK; Wood, KM | 1 |
| Borowczyk, K; Jakubowski, H; Suliburska, J | 1 |
| da Silva, EP; de Freitas, LW; de Lima, MB; Dias, CTS; Menten, JFM; Pereira, R; Romano, GG | 1 |
| Bassett, CJ; Cruickshank-Quinn, C; Johnson, LC; Martens, CR; McQueen, MB; Reisdorph, N; Santos-Parker, JR; Seals, DR; Strahler, TR | 1 |
| Cui, L; Gao, YP; Ji, S; Liu, FX; Min, YN; Qi, X; Wang, ZP | 1 |
| Akbergenov, R; Böttger, EC; Boukari, H; Duscha, S; Eckert, A; Frank, S; Freihofer, P; Fritz, AK; Isnard-Petit, P; Juskeviciene, R; Oettinghaus, B; Oishi, N; Rehrauer, H; Schacht, J; Schmitt, K; Shcherbakov, D; Teo, Y; Thiam, K; Westhof, E; Wolfer, D | 1 |
| Bárcena, C; Kroemer, G; López-Otín, C | 1 |
| Ostrakhovitch, EA; Tabibzadeh, S | 1 |
| Moskovitz, J; Oien, DB | 2 |
| Bacon, ER; Brinton, RD; Desai, MK; Mishra, A; Wang, Y; Yin, F | 1 |
| Hoffman, JM; Jones, DP; Promislow, DEL; Ross, C; Tardif, S; Tran, V | 1 |
| Brown, BM; Castalanelli, N; Doecke, J; Laws, SM; Martins, RN; Peiffer, JJ; Rainey-Smith, SR; Sohrabi, HR; Weinborn, M | 1 |
| Liang, M; Liao, Z; Wei, Y; Xu, H; Zhang, Q | 1 |
| Gao, AW; Houtkooper, RH; Janssens, GE; Jongejan, A; Kamble, R; Liu, YJ; MacInnes, AW; McIntyre, RL; Molenaars, M; Weeghel, MV | 1 |
| Cai, GY; Chen, XM; Li, P; Liu, JQ; Song, YH; Sun, XF; Wang, SY; Wang, WJ | 1 |
| Jamie, J; Kwan, AH; Lyons, B; Truscott, RJ | 1 |
| Barja, G; Sanchez-Roman, I | 1 |
| Au, C; Cabreiro, F; Cochemé, HM; Gems, D; Greene, ND; Leung, KY; Noori, T; Schuster, E; Vergara-Irigaray, N; Weinkove, D | 1 |
| Ayala, V; Cabré, R; Jové, M; Naudí, A; Pamplona, R; Portero-Otín, M; Ramírez-Núñez, O; Spickett, CM | 1 |
| Brown-Borg, HM; Rakoczy, S | 1 |
| Bäckman, L; Bertram, L; Heekeren, HR; Li, SC; Lindenberger, U; Nagel, IE; Nietfeld, W; Papenberg, G; Schröder, J | 1 |
| Klein, JC; Moen, RJ; Thomas, DD | 1 |
| Bäckman, L; Bertram, L; Brandmaier, AM; Gerstorf, D; Ghisletta, P; Lindenberger, U; Liu, T | 1 |
| Gerashchenko, MV; Gladyshev, VN; Harshman, LG; Hu, Z; Kaya, A; Kim, G; Lee, BC; Ma, S; Yim, SH | 1 |
| Anstey, KJ; Bielak, AA; Cherbuin, N; Das, D; Easteal, S; Tan, X | 1 |
| Horn, MM; Kalich, AG; Kennedy, KM; Meerbrey, ME; Reese, ED; Rodrigue, KM; Sizemore, AN; Unni, AK | 1 |
| Severin, FF; Skulachev, MV; Skulachev, VP | 1 |
| Hine, C; Mitchell, JR | 1 |
| Ganeko, K; Hosokawa, R; Kondo, Y; Masaki, C; Miyazaki, T; Mukaibo, T; Nakamoto, T; Shibata, Y | 1 |
| Brown-Borg, HM | 1 |
| Gladyshev, VN; Kaya, A; Lee, BC | 1 |
| Dammann, P; Dziegelewska, M; Groth, M; Hildebrandt, T; Holtze, S; Huse, K; Menzel, U; Morhart, M; Platzer, M; Sahm, A; Sponholz, C; Szafranski, K; Vole, C; Wachter, U | 1 |
| Buffenstein, R; Gibney, PA; Lewis, KN; McIsaac, RS | 1 |
| Asara, JM; Binari, R; Demontis, F; Parkhitko, AA; Perrimon, N; Zhang, N | 1 |
| Brown, PA; Delibegovic, M; Forney, LA; Gettys, T; Grant, L; Lees, EK; Mody, N; Wilson, HM | 1 |
| Brown-Borg, HM; Buffenstein, R | 1 |
| Nacarelli, T; Sell, C | 1 |
| de Vries, LP; Korosi, A; Lucassen, PJ; Naninck, EF; Oosterink, JE; Plantinga, JA; Plosch, T; Schierbeek, H; van Goudoever, JB; Verkaik-Schakel, RN; Yam, KY | 1 |
| Georgescu, C; Kim, G; Levine, RL; Liu, C; Richardson, A; Salmon, AB; Wren, JD | 1 |
| Ables, GP; Locasale, JW; Mattocks, DA; Mentch, SJ; Nichenametla, SN; Richie, JP; Shneyder, J; Sun, D | 1 |
| Ables, GP; Johnson, JE | 1 |
| Chen, L; Derous, D; Douglas, A; Green, CL; Han, JJ; Lusseau, D; Mitchell, SE; Promislow, DEL; Speakman, JR; Wang, Y | 1 |
| Cogger, VC; Cooney, GJ; Fontana, L; Le Couteur, DG; Raubenheimer, D; Simpson, SJ; Solon-Biet, SM | 1 |
| Berenshtein, E; Chevion, M; Eliashar, R; Grinberg, L; Gross, M; Moskovitz, J; Reznick, AZ; Vinokur, V | 1 |
| Hipkiss, AR | 2 |
| Aftab, U; Ashraf, M | 1 |
| Arango, V; Baca-Garcia, E; Galfalvy, H; Huang, YY; Mann, JJ; Oquendo, MA; Parsey, RV; Rodrigues, SM; Sublette, ME | 1 |
| Aulchenko, YS; Claes, S; Hofman, A; Janssens, AC; López-León, S; Oostra, BA; Snijders, PJ; Tiemeier, H; van Duijn, CM | 1 |
| Barker, RA; Bishop, S; Fallon, S; Hughes, L; Owen, AM; Rowe, JB; Williams-Gray, CH | 1 |
| Donchenko, HV; Kuchmenko, OB; Petukhov, DM; Sahach, VF; Strutyns'ka, NA; Timoshchuk, SV; Vavilova, HL | 1 |
| Barroso-Aranda, J; Contreras, F; McCarty, MF | 1 |
| Berenshtein, E; Bulvik, B; Chevion, MM; Eliashar, R; Grinberg, L | 1 |
| Kennedy, KM; Land, S; Raz, N; Rodrigue, KM | 1 |
| Chavan, B; Decker, H; Hartmann, H; Hasse, S; Paus, R; Rokos, H; Schallreuter, KU; Shalbaf, M; Spencer, JD; Thornton, MJ; Wood, JM | 1 |
| Burns, JM; Canello, T; Gabizon, R; Gasset, M; Lundquist, BL; Moskovitz, J; Oien, DB | 1 |
| Harper, JM; Miller, RA; Sadighi Akha, AA; Sun, L | 1 |
| Kotsiuruba, AV; Sahach, VF; Strutyns'ka, NA; Timoshchuk, SV; Vavilova, HL | 1 |
| Burrin, D; Castillo, L; Chacko, S; Gordon, WE; Hsu, J; Sy, J; Verbruggen, S; Wu, M; Zurakowski, D | 1 |
| Donchenko, HV; Kuchmenko, OB; Petukhov, DM; Sahach, VF; Strutyns'ka, NA; Talanov, SA; Timoshchuk, SV; Vavilova, HL | 1 |
| Calevo, MG; Cotellessa, M; d'Annunzio, G; Giannattasio, A; Gianotti, D; Lorini, R; Minniti, G; Napoli, F | 1 |
| Bäckman, L; Chicherio, C; Heekeren, HR; Li, SC; Lindenberger, U; Nagel, IE; Nyberg, L; Papenberg, G; Sander, T; von Oertzen, T | 1 |
| Li, Y; Liu, Y; Richardson, B; Strickland, FM | 1 |
| Callicott, JH; Das, S; Goldberg, TE; Lemaitre, HS; Mattay, VS; Murty, VP; Reed, JD; Sambataro, F; Weinberger, DR | 1 |
| Page, MM; Robb, EL; Salway, KD; Stuart, JA | 1 |
| Hirota, M; Morisawa, H; Nakamura, M; Nishigaki, R; Toda, T; Yoshimi, Y | 1 |
| Auwerx, J; Houtkooper, RH; Williams, RW | 1 |
| Gladyshev, VN; Lee, BC | 1 |
| Nagata, T; Ohata, K; Takami, T; Terakawa, Y; Tsuyuguchi, N; Uda, T | 1 |
| Erickson, KI; Miller, DL; Roecklein, KA | 1 |
| Bloomer, RJ; Canale, RE; Kabir, MM; Marshall, KE; Trepanowski, JF | 1 |
| Grune, T; Kastle, M | 1 |
| Libert, C; Vanhooren, V | 1 |
| Ademoglu, E; Tanrikulu-Kucuk, S | 1 |
| Barja, G; Gómez, A; Jové, M; Lopez-Torres, M; Naudí, A; Pamplona, R; Pérez, I; Sanchez, C; Sanchez-Roman, I; Suarez, H | 1 |
| Andersen, JH; Buttenschøn, HN; Børglum, AD; Elfving, B; Foldager, L; Grynderup, MB; Hansen, ÅM; Kaerlev, L; Kolstad, HA; Mikkelsen, S; Mors, O; Poulsen, PH; Thomsen, JF; Wegener, G | 1 |
| Ablao, KP; Bodmer, R; Dhahbi, JM; Li, R; Mote, P; Ocorr, K; Spindler, SR; Wang, Y; Williams, RT; Yamakawa, A | 1 |
| Malloy, VL; Orentreich, DS; Orentreich, N; Perrone, CE | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Beste, C; Falkenstein, M; Gajewski, PD; Golka, K; Hengstler, JG | 1 |
| Kim, HY | 1 |
| Hashimoto, R; Iijima, M; Kamei, H; Kawagashira, Y; Kiuchi, T; Koike, H; Nakamura, T; Sobue, G; Tomita, M; Watanabe, H | 1 |
| Coccheri, S; Cosmi, B; Grossi, G; Legnani, C; Musolesi, S; Palareti, G; Sassi, S | 1 |
| Benes, JJ; Mockett, RJ; Orr, WC; Radyuk, SN; Sohal, RS | 1 |
| Aoki, S; Itoh, S; Iwata, T; Katagiri, T; Mukae, S; Nishio, K; Sato, R | 1 |
| Alpérovitch, A; Amant, C; Amouyel, P; Berr, C; Hauw, JJ; Helbecque, N; Mohr, M; Sazdovitch, V | 1 |
| Brown-Borg, HM; Uthus, EO | 1 |
| Friguet, B | 1 |
| Smith, DL; Smith, JB; Zhang, Z | 1 |
| LYMAN, MM; OKEY, R | 1 |
| OERIU, S; PARHON, CI | 1 |
| FONTAINE, R; MANDEL, P; PANTESCO, V | 1 |
| Malhotra, OP; Reber, EF | 1 |
| GUTMAN, E; HAJEK, I; JAKOUBEK, B; ROHLICEK, V; SKALOUD, J | 1 |
| Levine, RL; Moskovitz, J; Stadtman, ER | 1 |
| Noy, Y; Sklan, D | 4 |
| Stadtman, ER | 3 |
| Fujii, N; Kamei, A; Kuge, K; Saito, T; Takata, T; Takeuchi, N; Tezuka, T | 1 |
| Bakun, P; Dallal, GE; Olson, B; Rosenberg, IH; Selhub, J; Tucker, KL | 1 |
| Hartmann, B; Krems, C; Lührmann, PM; Neuhäuser-Berthold, M; Strassburg, A | 1 |
| Adolfsson, R; Annerbrink, K; de Frias, CM; Eriksson, E; Nilsson, LG; Westberg, L | 1 |
| de Souza, KB; de Souza, MR; Feoli, AM; Krüger, AH; Perry, CT; Perry, ML; Rotta, LN; Souza, DO | 1 |
| Robinson, M; Williams, SM | 1 |
| Bigelow, DJ; Squier, TC | 1 |
| Levine, RL; Richardson, A; Stadtman, ER; Van Remmen, H; Wehr, NB | 1 |
| Davenport, RJ | 1 |
| Moskovitz, J | 1 |
| Buehner, G; Chang, Y; Harper, JM; Miller, RA; Sigler, R; Smith-Wheelock, M | 1 |
| Motobayashi, S; Nakamuro, K; Okuno, T; Ueno, H | 1 |
| Packer, L; Paetau-Robinson, I; Rebrin, I; Sohal, RS; Wedekind, KJ; Zicker, S | 1 |
| Backlund, PS; Bityurin, NM; Chelnokov, EV; Hejtmancik, JF; Ostrovsky, MA; Sergeev, YV; Soustov, LV; Wingfield, PT | 1 |
| Fleisher, LN; Goralska, M; McGahan, MC; Nagar, S | 1 |
| Friguet, B; Moreau, M; Nizard, C; Perichon, M; Petropoulos, I; Picot, CR | 1 |
| Brown, SE; Champagne, FA; Dymov, S; Meaney, MJ; Sharma, S; Szyf, M; Weaver, IC | 1 |
| Chirieac, DV; Cianci, J; Collins, HL; Galloway, CA; Jokinen, J; Sowden, MP; Sparks, CE; Sparks, JD | 1 |
| Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I | 1 |
| Meaney, MJ; Szyf, M; Weaver, IC | 1 |
| Hou, SS; Huang, W; Xie, M | 1 |
| Ingenbleek, Y | 1 |
| Bartke, A; Bonkowski, M; Chang, Y; Harper, JM; Miller, RA; Salmon, AB | 1 |
| Bailey, SJ; Hristopoulos, G; Krajcik, RA; Malloy, VL; Orentreich, N; Plummer, JD | 1 |
| Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Ersen, FY; Moskovitz, J; Oien, DB; Pal, R | 1 |
| Gladyshev, VN; Koc, A | 1 |
| Deary, IJ; Fox, H; Harris, SE; Starr, JM; Whalley, LJ | 1 |
| Barja, G; Pamplona, R | 1 |
| Zhinkin, LN | 1 |
| Kinkead, AM; Lipton, MA; Prange, AJ; White, JE | 1 |
| Babický, A; Fischer, J; Gutmann, E; Jakoubek, B | 2 |
| Baribault, H; Goyette, R; Leroux-Nicollet, I; Marceau, N; Noel, M | 1 |
| Gregor, P; Sellinger, OZ | 1 |
| Alvarez Chiva, V; Marin-Cao, D; Mato, JM | 1 |
| Benevenga, NJ; Finkelstein, A | 1 |
| Bada, JL; Boehm, MF | 1 |
| Aiello, VR; Massie, HR | 1 |
| Benevenga, NJ; Egan, AR; Radcliffe, BC | 1 |
| Kream, RM; Margolis, FL | 1 |
| Connor, AM; Kavanaugh, A; Nauss, KM; Newberne, PM | 1 |
| Leibholz, J; Wilson, RH | 1 |
| Landis, WA; Webster, GC; Webster, SL | 1 |
| Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R | 1 |
| Buetow, DE; Cook, JR | 1 |
| Cramer, F; Deerberg, F; Engelhardt, R; Gabius, HJ | 1 |
| Barak, AJ; Kemmy, RJ | 1 |
| Garner, MH; Spector, A | 1 |
| Janson, VE; Owens, LK; Sastry, BV | 1 |
| Fisher, C; Scougall, RK | 1 |
| Huxtable, RJ; Lippincott, SE | 1 |
| Bone, AH; Taufek, HR | 1 |
| Burgoyne, RD; Murphy, S; Rudge, JS | 1 |
| Burns, ER; Casciano, DA; Duffy, PH; Feuers, RJ; Hart, R; Hinson, WG; Lyn-Cook, LE; Pipkin, JL | 1 |
| Noguchi, T; Tanaka, T; Yamamoto, N | 1 |
| Joseph, JA; Kelly, J; Roth, GS; Villalobos-Molina, R; Yamagami, K | 1 |
| Foster, PM; McLaren, TT; Sharpe, RM | 1 |
| Morris, EA; Treadwell, BV | 1 |
| Fujii, N; Fujino, M; Harada, K; Ishibashi, Y; Satoh, K | 1 |
| Abou-Haila, A; Bendahmane, M | 1 |
| Alvares, K; Kanwar, YS; Kumar, A; Liu, ZZ; Makino, H; Wada, J; Wallner, E | 1 |
| Behar, KL; Ogino, T | 1 |
| Kitoh, J; Kuroda, T; Masuda, K; Mizobuchi, M; Nakano, K; Takahashi, S | 1 |
| Gu, MJ; Heydari, AR; Richardson, A; Wu, B | 1 |
| Jeroch, H; Pack, M | 1 |
| Dritz, SS; Goodband, RD; Nelssen, JL; Owen, KQ; Tokach, MD | 1 |
| Dargel, R; Lorentz, A; Plonné, D; Schulze, HP | 1 |
| Chao, CC; Ma, YS; Stadtman, ER | 1 |
| Edwards, SL; Ma, KN; Potter, JD; Schaffer, D; Slattery, ML | 1 |
| Abe, M; Funaba, M; Iriki, T | 1 |
| Hoffman, RM | 1 |
| Douglas, MW; Johnson, ML; Parsons, CM | 1 |
| Gao, J; Squier, TC; Williams, TD; Yao, Y; Yin, D | 1 |
| Biesiada, H; Ferrington, DA; Gao, J; Squier, TC; Sun, H; Williams, TD | 1 |
| Moustapha, A; Robinson, K | 1 |
| Ferrington, DA; Schöneich, C; Sharov, VS; Squier, TC | 1 |
| Asaithambi, A; Mukherjee, S; Thakur, MK | 1 |
| Chao, CL; Kuo, TL; Lee, YT | 1 |
| Jung, C; Shea, TB; Yabe, JT | 1 |
| Bagley, LC; Miller, J; Rosenberg, IH; Selhub, J | 1 |
| Refsum, H; Schneede, J; Ueland, PM | 1 |
| Brannon, JA; Carlson, CW; Noll, SL; Waibel, PE | 1 |
| Kim, C; Nielsen, HC | 1 |
| Ferket, PR; Kwakkel, RP; Nixey, C; Noordhuizen, JP; Veldkamp, T | 1 |
| Buddington, RK; Elnif, J; Malo, C; Sangild, PT | 1 |
| Bousquet, B; Gamra, S; Gourmel, B; Houze, P; Madelaine, I | 1 |
| Howard, PM; Mulvihill, A; Naughten, ER; O'Keefe, M; Yap, S | 1 |
| Panini, R; Salvioli, G; Scarpetta, G; Ventura, P; Verlato, C | 1 |
| Achon, M; Alonso-Aperts, E; Varela-Moreiras, G | 1 |
| Carminatti, H; Radrizzani, M; Santa-Coloma, TA; Vilá-Ortiz, GJ | 1 |
| DeBey, BM; Lambert, BD; Löest, CA; Stokka, GL; Titgemeyer, EC | 1 |
| Nakajima, T; Tanaka, T | 1 |
| McClure, WO; McLane, JA | 1 |
| Daniels, VG; Murphy, S | 1 |
| Strittmatter-Ackerschott, E; Verzár, F | 1 |
| Lerner, J; Rush, R; Sattelmeyer, P | 1 |
| Kent, S | 1 |
| Gebhardt, BM; Morton, B; Newberne, PM; Williams, EA | 1 |
| Lane, RS; Prasanna, HR | 1 |
| Fu, PC; Ozimy, K; Zic, V | 1 |
| Benedetti, C; Biondi, R; Rossi, R; Viola-Magni, MP | 1 |
| Edwards, BB; Filer, LJ; Fomon, SJ; Nelson, SE; Ziegler, EE | 1 |
| Endres, W; Seibold, H | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, WE; Martin, JJ | 1 |
| Foppen, FH; Kopin, IJ; Liuzzi, A | 1 |
| Georgi, GR; Kalbe, I; Reinhardt, C; Schmidt, UJ; Weber, R | 1 |
| Cutler, RG; Ogrodnik, JP; Wulf, JH | 1 |
| Huxtable, RJ; Lleu, PL | 1 |
| Benowitz, LI; Moya, KL; Sabel, BA; Schneider, GE | 1 |
| Brophy, PJ; Gillespie, CS; Kelly, BM | 1 |
| Andersson, A; Brattström, L; Hamfelt, A; Hultberg, B; Isaksson, A; Israelsson, B | 1 |
| Burchill, SA | 1 |
| Poduslo, JF | 1 |
| Holt, PR; Yeh, KY; Yeh, M | 1 |
| Dannals, RF; Loats, HA; Loats, S; O'Tuama, LA; Phillips, PC; Ravert, HT; Smith, QR; Uno, Y; Wagner, HN; Wilson, AA | 1 |
| Heinlein, UA; Lemaire, L | 1 |
| Costabel, U; Leuschel, L; Maier, K | 1 |
| Buhi, WC; Ogilvie, S; Olson, JA; Raizada, MK; Shiverick, KT | 1 |
| Castillo, RO; Gray, GM; Kwong, LK; Quan, R; Reisenauer, AM; Tsuboi, KK | 1 |
| Hyland, K; Surtees, R | 1 |
| Bloemendal, H; De Haard-Hoekman, WA; De Jong, WW; Hermans, MM; Voorter, CE | 1 |
| Banay-Schwartz, M; Lajtha, A; Palkovits, M | 1 |
| Asensi, M; Ferrer, JV; Gascó, E; Pallardó, FV; Sastre, J; Viña, J | 1 |
| Chanderkar, LP; Kim, S; Paik, WK | 1 |
| Ayala, A; Bautista, J; Gordillo, E; Machado, A | 1 |
| Story, MT | 1 |
| Klaude, M; von der Decken, A | 3 |
| Prasad, S; Thakur, MK | 1 |
| Wilson, RP | 1 |
| Ayala, A; Bautista, J; F-Lobato, M; Gordillo, E; Machado, A | 1 |
| Fau, D; Hadjiisky, P; Peret, J | 1 |
| Bensch, KG; Chandra, D; Fleming, JE; Latter, GI; Melnikoff, PS | 1 |
| Dhalla, NS; Jasmin, G; Okumura, K; Panagia, V | 1 |
| Brattström, LE; Hardebo, JE; Hultberg, BL | 1 |
| Bensch, KG; Dubitsky, R; Fleming, JE | 1 |
| Bourdel, G; Forestier, M; Girard, A | 1 |
| Fenshin, KM; Kuprasch, LP; Oranskaja, SA; Saika, MU; Sapadnjuk, WI; Strishowa-Salowa, NI | 1 |
| Moser, P; Verzár, F | 1 |
| Duerre, JA; Lee, CT | 1 |
| Kaulenas, MS; Unsworth, BR | 1 |
| Gruss, R; Icekson, I; Kaye, AM; Lamprecht, SA; Lindner, HR; Tsafriri, A | 1 |
| Deamer, D; Fletcher, B; Tappel, A | 1 |
| Kim, S; Paik, WK | 1 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| De Luca, F; Macaione, S; Ruggeri, P; Tucci, G | 1 |
| Bloemendal, H; Gerding, JJ; Schoenmakers, JG | 1 |
| Seemayer, G | 1 |
| Abbott, JM; Oace, SM | 1 |
| Fondy, TP; Ross, CR; Solomon, J | 1 |
| Finkelstein, JD; Harris, BJ; Kyle, W | 1 |
| Curri, SB | 1 |
| Lawson, D; Lee, HW; Paik, WK | 1 |
| Costello, R; Dubos, R; Schaedler, RW | 1 |
| Johnson, HD; Yousef, MK | 1 |
| Cherevichnaia, EV | 1 |
| Miller, SA; Seitz, AW; Tannenbaum, SR | 1 |
| Lombardini, JP; Russell, DH | 1 |
| Gutmann, E | 1 |
| Cho, GJ; McConnell, KP; Nixon, CW | 1 |
| Pénzes, L; Simon, G; Winter, M | 2 |
| Short, FA | 1 |
| Weinhold, PA | 1 |
| Remy, CN; Wells, IC | 1 |
| Mende, TJ; Viamonte, LM | 1 |
44 review(s) available for methionine and Aging
| Article | Year |
|---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
Glycine and aging: Evidence and mechanisms.
Topics: Aging; Animals; Glycine; Glycine N-Methyltransferase; Humans; Longevity; Mammals; Methionine; Mice; Racemethionine; Rats; Sarcosine | 2023 |
Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species.
Topics: Aging; Animals; Humans; Longevity; Methionine; Methyltransferases; Species Specificity | 2019 |
Epigenetic insights into multiple sclerosis disease progression.
Topics: Acetylation; Aging; Brain; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Disease Progression; DNA Methylation; Epigenesis, Genetic; Genetic Variation; Genome-Wide Association Study; Histones; Humans; Immunogenetic Phenomena; Life Style; Methionine; Multiple Sclerosis; Oligodendroglia; Quantitative Trait Loci; Signal Transduction; Tobacco Smoke Pollution | 2020 |
Methionine sulfoxide and the methionine sulfoxide reductase system as modulators of signal transduction pathways: a review.
Topics: Aging; Animals; Humans; Methionine; Methionine Sulfoxide Reductases; Oxidation-Reduction; Oxidative Stress; Signal Transduction | 2021 |
Lessons from animal nutritionists: dietary amino acid requirement studies and considerations for healthy aging studies.
Topics: Aging; Amino Acids; Amino Acids, Sulfur; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Cell Differentiation; Cell Proliferation; Dietary Proteins; Energy Metabolism; Lipogenesis; Longevity; Mechanistic Target of Rapamycin Complex 1; Methionine; Methylation; Reactive Oxygen Species; Signal Transduction | 2018 |
Genetic regulation of longevity and age-associated diseases through the methionine sulfoxide reductase system.
Topics: Aging; Animals; Gene Expression Regulation; Humans; Longevity; Methionine; Methionine Sulfoxide Reductases; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress | 2019 |
Regulation of longevity and oxidative stress by nutritional interventions: role of methionine restriction.
Topics: Aging; Animals; Diet; DNA Damage; DNA, Mitochondrial; Longevity; Methionine; Mice; Mitochondria; Oxidative Stress; Rats; Reactive Oxygen Species | 2013 |
Electron paramagnetic resonance resolves effects of oxidative stress on muscle proteins.
Topics: Actomyosin; Aging; Animals; Electron Spin Resonance Spectroscopy; Methionine; Myosins; Oxidative Stress | 2014 |
Calorie restriction and methionine restriction in control of endogenous hydrogen sulfide production by the transsulfuration pathway.
Topics: Aging; Animals; Caloric Restriction; Humans; Hydrogen Sulfide; Invertebrates; Longevity; Mammals; Methionine; Mice; Models, Animal; Rats; Rodentia; Signal Transduction; Yeasts | 2015 |
Reduced growth hormone signaling and methionine restriction: interventions that improve metabolic health and extend life span.
Topics: Aging; Animals; Caloric Restriction; Energy Metabolism; Growth Hormone; Health; Life Expectancy; Longevity; Methionine; Mice; Mitochondria; Models, Animal; Phenotype; Phosphorylation; Rats; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Methionine restriction and life-span control.
Topics: Aging; Animals; Caloric Restriction; Diet; Diet, Protein-Restricted; Health; Humans; Longevity; Methionine; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span.
Topics: Aging; Animals; Caloric Restriction; Cysteine; Eukaryotic Cells; Humans; Invertebrates; Life Expectancy; Longevity; Metabolic Networks and Pathways; Methionine; Models, Animal; Rodentia; Yeasts | 2016 |
Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan?
Topics: Aging; Amino Acids; Animals; Caloric Restriction; Diet; Diet, Protein-Restricted; Healthy Aging; Humans; Longevity; Methionine; Quality of Life; Tryptophan | 2017 |
Targeting metabolism in cellular senescence, a role for intervention.
Topics: Aging; Animals; Cell Cycle Proteins; Cellular Senescence; Cytokines; Electron Transport Chain Complex Proteins; Gene Expression Regulation; Glucose; Humans; Mechanistic Target of Rapamycin Complex 1; Methionine; Mitochondria; Phenotype; Signal Transduction; Sirolimus | 2017 |
Pleiotropic responses to methionine restriction.
Topics: Aging; Animals; Bone Development; Caenorhabditis elegans; Cardiovascular System; Drosophila melanogaster; Epithelial Cells; Gene Expression Regulation; Humans; Longevity; Methionine; Neoplasms; Stress, Physiological; Tight Junctions; Yeasts | 2017 |
Dietary protein, aging and nutritional geometry.
Topics: Aging; Animals; Caloric Restriction; Diet, Protein-Restricted; Dietary Proteins; Energy Intake; Humans; Longevity; Methionine; Models, Animal; Nutritional Status | 2017 |
Protein carbonyl and the methionine sulfoxide reductase system.
Topics: Aging; Animals; Humans; Methionine; Methionine Sulfoxide Reductases; Mice; Models, Biological; Neurodegenerative Diseases; Oxidoreductases; Protein Carbonylation | 2010 |
Mitochondrial redox metabolism: aging, longevity and dietary effects.
Topics: Aging; Animals; Caloric Restriction; Diet; Dietary Supplements; Longevity; Methionine; Mitochondria; Oxidation-Reduction; Rats; Reactive Oxygen Species | 2010 |
Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging.
Topics: Aging; Alzheimer Disease; Animals; Cysteine; Electrophoresis, Gel, Two-Dimensional; Humans; Isoelectric Focusing; Methionine; Oxidative Stress; Protein Biosynthesis; Protein Carbonylation; Proteomics; Reactive Oxygen Species | 2010 |
The biological significance of methionine sulfoxide stereochemistry.
Topics: Aging; Animals; Humans; Methionine; Oxidation-Reduction; Oxidoreductases; Stereoisomerism | 2011 |
The aging hippocampus: interactions between exercise, depression, and BDNF.
Topics: Aging; Animals; Atrophy; Brain-Derived Neurotrophic Factor; Depression; Exercise; Genotype; Hippocampus; Humans; Memory; Methionine; Mice; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Rats; Valine | 2012 |
Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings.
Topics: Adult; Aged; Aging; Animals; Biomarkers; Caloric Restriction; Cardiovascular Physiological Phenomena; Cholesterol, HDL; Cholesterol, LDL; Christianity; Diet, Reducing; Dietary Proteins; Energy Intake; Exercise; Fasting; Female; Humans; Islam; Life Expectancy; Longevity; Male; Methionine; Middle Aged; Motor Activity; Religion; Tryptophan | 2011 |
Protein oxidative modification in the aging organism and the role of the ubiquitin proteasomal system.
Topics: Aging; Animals; Atherosclerosis; Eye Diseases; Glycation End Products, Advanced; Humans; Methionine; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Carbonylation; Protein Multimerization; Skin Aging; Ubiquitins | 2011 |
The mouse as a model organism in aging research: usefulness, pitfalls and possibilities.
Topics: Aging; Animals; Caloric Restriction; Crosses, Genetic; Humans; Hypophysectomy; Life Expectancy; Longevity; Methionine; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, Mutant Strains; Models, Biological; Models, Genetic; Reference Values; Research | 2013 |
Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents.
Topics: Adaptation, Physiological; Adiposity; Age Factors; Aging; Animals; Diet; Energy Metabolism; Humans; Insulin Resistance; Methionine; Mice; Oxidative Stress; Phenotype; Rats; Rodentia | 2013 |
The methionine sulfoxide reduction system: selenium utilization and methionine sulfoxide reductase enzymes and their functions.
Topics: Aging; Animals; Catalysis; Eukaryotic Cells; Humans; Mammals; Metabolic Networks and Pathways; Methionine; Methionine Sulfoxide Reductases; Oxidation-Reduction; Selenium; Selenocysteine; Selenoproteins; Substrate Specificity | 2013 |
Protein repair and degradation during aging.
Topics: Aging; Animals; Cysteine Endopeptidases; Humans; Methionine; Methionine Sulfoxide Reductases; Multienzyme Complexes; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Proteasome Endopeptidase Complex; Proteins | 2002 |
Oxidation of methionine residues of proteins: biological consequences.
Topics: Aging; Alzheimer Disease; Animals; Cysteine Endopeptidases; Humans; Methionine; Methionine Sulfoxide Reductases; Models, Chemical; Multienzyme Complexes; Oxidation-Reduction; Oxidoreductases; Proteasome Endopeptidase Complex; Proteins; Reactive Oxygen Species; Signal Transduction | 2003 |
Cyclic oxidation and reduction of methionine residues of proteins in antioxidant defense and cellular regulation.
Topics: Aging; Animals; Antioxidants; Humans; Methionine; Oxidation-Reduction; Proteins | 2004 |
Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins.
Topics: Aging; Calcium; Calcium-Transporting ATPases; Calmodulin; Methionine; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Signal Transduction | 2005 |
Methionine oxidation and aging.
Topics: Aging; Animals; Humans; Methionine; Mice; Oxidation-Reduction; Rats | 2005 |
Roles of methionine suldfoxide reductases in antioxidant defense, protein regulation and survival.
Topics: Aging; Animals; Antioxidants; Humans; Methionine; Methionine Sulfoxide Reductases; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Proteins; Selenoproteins | 2005 |
The nutritional relationship linking sulfur to nitrogen in living organisms.
Topics: Aging; Animals; Body Composition; Diet; Homeostasis; Homocysteine; Humans; Methionine; Methylation; Nitrates; Nitrogen; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Prealbumin; Protein Deficiency; Stress, Physiological; Sulfates; Sulfur | 2006 |
Protein oxidation and aging.
Topics: Aging; Amino Acids; Animals; Cross-Linking Reagents; Humans; Lysine; Methionine; Oxidation-Reduction; Proteins; Reactive Oxygen Species | 2006 |
Highly resistant macromolecular components and low rate of generation of endogenous damage: two key traits of longevity.
Topics: Aging; Animals; Dietary Proteins; DNA Damage; DNA, Mitochondrial; Humans; Lipid Metabolism; Longevity; Methionine; Oxidative Stress; Reactive Oxygen Species | 2007 |
The complement of cytoplasmic tRNAs, including queuosine-containing tRNAs, in adult and senescent Wistar rat liver and their levels of aminoacylation.
Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Cytoplasm; Female; Guanosine; Liver; Methionine; Nucleoside Q; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Transfer; RNA, Transfer, Amino Acyl | 1982 |
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease.
Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins | 1997 |
Homocysteine: an emerging age-related cardiovascular risk factor.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Menopause; Methionine; Middle Aged; Prevalence; Primary Health Care; Risk Factors | 1999 |
B vitamins, homocysteine, and neurocognitive function in the elderly.
Topics: Aging; Animals; Brain; Cognition Disorders; Homocysteine; Humans; Methionine; Tetrahydrofolates; Vitamin B Deficiency | 2000 |
Biological and environmental determinants of plasma homocysteine.
Topics: Adult; Aged; Aging; Alcohol Drinking; Child; Cystathionine beta-Synthase; Diagnosis-Related Groups; Dietary Proteins; Endocrine System Diseases; Female; Folic Acid Antagonists; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Inflammation; Intestinal Diseases; Life Style; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Niacin; Nitrous Oxide; Norway; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Renal Insufficiency; Smoking; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Protein oxidation in aging and age-related diseases.
Topics: Aging; Amino Acids; Animals; Antioxidants; Apoptosis; Cross-Linking Reagents; Cysteine; Disease; Humans; Longevity; Methionine; Models, Biological; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptides; Peroxynitrous Acid; Protein Denaturation; Proteins; Rats; Reactive Oxygen Species; Tyrosine | 2001 |
Do free radicals and dietary antioxidants wage intracellular war?
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Catechols; Cysteine; Cystine; Diet; Drug Combinations; Ethoxyquin; Female; Free Radicals; Humans; Life Expectancy; Lipid Metabolism; Male; Mercaptoethylamines; Methionine; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxides; Selenium; Superoxide Dismutase; Vitamin E | 1977 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
6 trial(s) available for methionine and Aging
| Article | Year |
|---|---|
Estimate of choline nutritional requirements for chicks from 1 to 21 days of age.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Choline; Diet; Dose-Response Relationship, Drug; Male; Methionine; Nutritional Requirements | 2018 |
Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2004 |
Methionine requirements of male white Peking ducks from twenty-one to forty-nine days of age.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dose-Response Relationship, Drug; Ducks; Male; Meat; Methionine; Muscle, Skeletal; Weight Gain | 2006 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
The effect of dietary methionine and its relationship to lysine on growth performance of the segregated early-weaned pig.
Topics: Aging; Animals; Cystine; Diet; Lysine; Methionine; Swine; Weaning | 1995 |
Methionine fortification of a soy protein formula fed to infants.
Topics: Aging; Blood Proteins; Body Height; Body Weight; Diet; Food, Fortified; Glycine max; Humans; Infant; Infant Food; Infant, Newborn; Male; Methionine; Plant Proteins, Dietary | 1979 |
241 other study(ies) available for methionine and Aging
| Article | Year |
|---|---|
A genetic model of methionine restriction extends
Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Animals, Genetically Modified; Carbon-Sulfur Lyases; Drosophila; Food; Humans; Longevity; Methionine; Models, Genetic | 2021 |
Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age.
Topics: Aging; Animals; Brain; Cerebellum; Chromatography; Frontal Lobe; Humans; Lipidomics; Lipids; Mass Spectrometry; Methionine; Oxidative Stress; Rats; Reactive Oxygen Species | 2021 |
S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Longevity; Methionine; S-Adenosylhomocysteine; Saccharomyces cerevisiae | 2022 |
Impact of methionine restriction on muscle aerobic metabolism and hypertrophy in young and old mice on an obesogenic diet.
Topics: Aging; Animals; Diet, High-Fat; Hypertrophy; Inflammation; Male; Methionine; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NAD; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A | 2022 |
Dietary methionine restriction improves gut microbiota composition and prevents cognitive impairment in D-galactose-induced aging mice.
Topics: Aging; Animals; Cognitive Dysfunction; Fatty Acids, Volatile; Galactose; Memory Disorders; Methionine; Mice; Mice, Inbred ICR; Racemethionine; Spatial Memory | 2022 |
Evolutionary paths to mammalian longevity through the lens of gene expression.
Topics: Aging; Animals; Gene Expression; Longevity; Mammals; Methionine | 2023 |
Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats.
Topics: Aging; Animals; Diet; Kidney; Male; Male Urogenital Diseases; Methionine; Rats; Rats, Inbred F344 | 2020 |
Withdrawal Effects Following Methionine Exposure in Adult Zebrafish.
Topics: Aging; Animals; Behavior, Animal; Brain; Methionine; Neurotransmitter Agents; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Zebrafish | 2020 |
Dietary Methionine Restriction Ameliorated Fat Accumulation, Systemic Inflammation, and Increased Energy Metabolism by Altering Gut Microbiota in Middle-Aged Mice Administered Different Fat Diets.
Topics: Aging; Animals; Bacteria; Diet, High-Fat; Dietary Fats; Energy Metabolism; Fats; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Male; Methionine; Mice; Mice, Inbred C57BL | 2020 |
Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue.
Topics: Aging; Animals; Diet, High-Fat; Granzymes; HMGB1 Protein; Inflammation; Interleukin-1; Intra-Abdominal Fat; Leptin; Mesenchymal Stem Cells; Methionine; Mice; Obesity; Proteome; Proto-Oncogene Proteins c-met; Receptor, Fibroblast Growth Factor, Type 2; RNA Precursors; RNA Processing, Post-Transcriptional; Secretory Vesicles; Signal Transduction; Transforming Growth Factor beta; Vascular Endothelial Growth Factor Receptor-2; Wnt Signaling Pathway | 2020 |
Methionine restriction plus overload improves skeletal muscle and metabolic health in old mice on a high fat diet.
Topics: Aging; Animals; Diet, High-Fat; Male; Methionine; Mice; Muscle, Skeletal; Obesity; Physical Conditioning, Animal | 2021 |
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Mechanistic Target of Rapamycin Complex 1; Methionine; Methyltransferases; Mice, Inbred C57BL; Muscle, Skeletal; Protein Biosynthesis; S-Adenosylmethionine; Signal Transduction | 2021 |
Tolerance to increased supplemented dietary intakes of methionine in healthy older adults.
Topics: Aged; Aging; Dietary Supplements; Dose-Response Relationship, Drug; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Reference Values | 2017 |
Methionine and/or Methionine Sulfoxide Alter Ectoenzymes Activities in Lymphocytes and Inflammatory Parameters in Serum from Young Rats: Acute and Chronic Effects.
Topics: Acetylcholinesterase; Adenine Nucleotides; Adenosine Deaminase; Aging; Animals; C-Reactive Protein; Cells, Cultured; Enzyme Activation; Interleukin-10; Interleukin-6; Lymphocytes; Methionine; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2018 |
Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.
Topics: Adult; Age of Onset; Aging; Amyloid Neuropathies, Familial; Anxiety; Chi-Square Distribution; Cognition Disorders; Depression; Female; Humans; Male; Methionine; Middle Aged; Mutation; Neurologic Examination; Neuropsychological Tests; Prealbumin; Statistics, Nonparametric; Valine | 2018 |
Demethylation of methionine and keratin damage in human hair.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Copper; Female; Hair; Homocysteine; Humans; Infant; Iron; Keratins; Male; Methionine; Methylation; Middle Aged | 2018 |
Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing.
Topics: Aging; Amino Acids; Exercise; Fatty Acids; Female; Gene Regulatory Networks; Health Status; Humans; Lipid Metabolism; Lipids; Male; Metabolome; Metabolomics; Methionine; Middle Aged; Young Adult | 2018 |
Effects of organic zinc on tibia quality, mineral deposit, and metallothionein expression level of aged hens.
Topics: Aging; Animals; Calcium; Chickens; Copper; Female; Liver; Metallothionein; Methionine; Organometallic Compounds; Tibia; Zinc | 2019 |
Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.
Topics: Aging; Animals; Behavior, Animal; Brain; Cysteine; Electron Transport Complex IV; Escherichia coli Proteins; Hearing Disorders; HEK293 Cells; Humans; Methionine; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Noise; Protein Biosynthesis; Ribosomal Proteins; Ribosomes; RNA, Messenger; Stress, Physiological | 2018 |
Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
Topics: Aging; Animals; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Caloric Restriction; Disease Models, Animal; Longevity; Methionine; Mice; Progeria; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Homocysteine and age-associated disorders.
Topics: Aged; Aging; Bone Diseases; Chronic Disease; Hearing Loss; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Quality of Life; Renal Insufficiency; Risk Factors | 2019 |
Neuroendocrine aging precedes perimenopause and is regulated by DNA methylation.
Topics: Aging; Animals; Decitabine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Enzyme Inhibitors; Epigenomics; Female; Genome-Wide Association Study; Hypothalamus; Menopause; Methionine; Neurosecretory Systems; Perimenopause; Rats, Sprague-Dawley; Reproduction; Signal Transduction; Transcription, Genetic | 2019 |
The metabolome as a biomarker of mortality risk in the common marmoset.
Topics: Aging; Animal Husbandry; Animals; Betaine; Biomarkers; Callithrix; Female; Male; Metabolome; Methionine; Mortality; Tryptophan | 2019 |
Influence of BDNF Val66Met on the relationship between cardiorespiratory fitness and memory in cognitively normal older adults.
Topics: Aged; Aged, 80 and over; Aging; Brain-Derived Neurotrophic Factor; Cardiorespiratory Fitness; Cognition; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Memory, Episodic; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Single Nucleotide | 2019 |
Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
Topics: Aging; Animals; Diet; Dietary Supplements; Fatty Acids; Lipid Metabolism; Liver; Methionine; Takifugu | 2019 |
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion.
Topics: Aging; Animals; Caenorhabditis elegans; Diet; Genes, Helminth; Glycine; Longevity; Metabolic Networks and Pathways; Methionine; Mutation; RNA Interference; Serine; Transcriptome | 2019 |
Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Caloric Restriction; Cell Line; Cellular Senescence; Cystathionine gamma-Lyase; Cytokines; Humans; Hydrogen Sulfide; Indican; Kidney; Kidney Diseases; Longevity; Male; Methionine; Mice; Mice, Inbred C57BL; Phosphorylation; TOR Serine-Threonine Kinases | 2019 |
Age-dependent modification of proteins: N-terminal racemization.
Topics: Aged; Aged, 80 and over; Aging; alpha-Crystallin B Chain; Amino Acid Sequence; Aquaporins; Eye Proteins; Humans; Isomerism; Lens, Crystalline; Methionine; Peptide Fragments; Proline; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Tandem Mass Spectrometry | 2013 |
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Topics: Adenylate Kinase; Aging; Animals; Biguanides; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Escherichia coli; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metagenome; Metformin; Methionine; Transcription Factors | 2013 |
Specific lipidome signatures in central nervous system from methionine-restricted mice.
Topics: Adaptation, Physiological; Aging; Animals; Brain; Cholesterol; Female; Lipid Metabolism; Liver; Longevity; Male; Methionine; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Reactive Oxygen Species; Spinal Cord; Ubiquinone | 2013 |
Metabolic adaptations to short-term every-other-day feeding in long-living Ames dwarf mice.
Topics: Adaptation, Physiological; Aging; Animals; Antioxidants; Body Weight; Caloric Restriction; Dwarfism; Feeding Behavior; Female; Kidney; Liver; Longevity; Male; Methionine; Mice; Mice, Mutant Strains; Muscle, Skeletal; Myocardium; Organ Size; Oxidative Phosphorylation | 2013 |
COMT polymorphism and memory dedifferentiation in old age.
Topics: Adult; Aged; Aging; Catechol O-Methyltransferase; Dopamine; Female; Genotype; Humans; Male; Memory; Memory, Episodic; Memory, Short-Term; Methionine; Middle Aged; Polymorphism, Genetic; Prefrontal Cortex; Valine; Young Adult | 2014 |
The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults.
Topics: Aged; Aged, 80 and over; Aging; Berlin; Brain-Derived Neurotrophic Factor; Cognition; Female; Homozygote; Humans; Longitudinal Studies; Male; Methionine; Mutation, Missense; Polymorphism, Genetic; Reaction Time; Sex Characteristics; Social Class; Valine | 2014 |
Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status.
Topics: Aging; Amino Acids; Animals; Caloric Restriction; Cell Cycle Proteins; Dietary Proteins; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Female; Longevity; Male; Methionine; Receptor Protein-Tyrosine Kinases; Reproduction; Saccharomyces cerevisiae; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
Cognitive ability, intraindividual variability, and common genetic variants of catechol-O-methyltransferase and brain-derived neurotrophic factor: a longitudinal study in a population-based sample of older adults.
Topics: Adult; Aged; Aging; Alleles; Brain-Derived Neurotrophic Factor; Catechol O-Methyltransferase; Cognition; Female; Genotype; Humans; Individuality; Longitudinal Studies; Male; Methionine; Middle Aged; Polymorphism, Genetic; Reaction Time; Valine; Young Adult | 2014 |
BDNF val66met polymorphism affects aging of multiple types of memory.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Brain-Derived Neurotrophic Factor; Cross-Sectional Studies; Female; Humans; Male; Memory; Mental Status Schedule; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Single Nucleotide; Valine; Young Adult | 2015 |
Receptor regulation of senile phenoptosis.
Topics: Aging; Animals; Caenorhabditis elegans; Caloric Restriction; Cold Temperature; Dietary Proteins; Eating; Humans; Macaca mulatta; Methionine; Mortality; Nociceptors; Signal Transduction; Starvation | 2014 |
Bone Aging by Advanced Glycation End Products: A Multiscale Mechanical Analysis.
Topics: Aging; Animals; Biomechanical Phenomena; Bone and Bones; Bone Development; Diet; Female; Glycation End Products, Advanced; Hardness Tests; Mandible; Methionine; Rabbits; Spectrum Analysis, Raman; Stress, Mechanical | 2015 |
Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
Topics: Aging; Animals; Cystathionine beta-Synthase; Diet; Hydrogen Sulfide; Liver; Longevity; Methionine; Mole Rats; Rats; S-Adenosylmethionine | 2016 |
Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila.
Topics: Aging; Animals; Brain; Down-Regulation; Drosophila melanogaster; Drosophila Proteins; Female; Heterochromatin; Intestines; Intracellular Signaling Peptides and Proteins; Longevity; Male; Methionine; Methylation; S-Adenosylhomocysteine | 2016 |
Methionine restriction improves renal insulin signalling in aged kidneys.
Topics: Aging; Animals; Female; Gene Expression Regulation; Insulin; Kidney; Male; Methionine; Mice; Signal Transduction | 2016 |
Early micronutrient supplementation protects against early stress-induced cognitive impairments.
Topics: Aging; Animals; Cognitive Dysfunction; Corticosterone; Diet; Dietary Supplements; Female; Housing, Animal; Male; Maternal Nutritional Physiological Phenomena; Methionine; Mice; Mice, Inbred C57BL; Micronutrients; Random Allocation; Stress, Physiological; Vitamin B Complex | 2017 |
Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice.
Topics: Aging; Animals; Cytosol; Female; Insulin Resistance; Longevity; Male; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Transgenic; Mitochondria; Models, Animal; Oxidative Stress | 2016 |
Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice.
Topics: Aging; Animals; Caloric Restriction; Diet; DNA Methylation; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Time Factors | 2017 |
The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice.
Topics: Aging; Animals; Bile Acids and Salts; Caloric Restriction; Carnitine; Catalase; Eating; Gene Expression Regulation; Insulin-Like Growth Factor I; Leptin; Liver; Lysophospholipids; Male; Metabolomics; Methionine; Mice; Mice, Inbred C57BL; Proteins; Receptors, Lysosphingolipid; Signal Transduction; Sphingolipids; Sphingosine | 2017 |
Methionine-centered redox cycle in organs of the aero-digestive tract of young and old rats.
Topics: Age Factors; Aging; Animals; Electron Transport Complex IV; Esophagus; Female; Gastrointestinal Tract; Larynx; Methionine; Methionine Sulfoxide Reductases; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Thioredoxin-Disulfide Reductase; Thioredoxins; Tongue | 2009 |
On methionine restriction, suppression of mitochondrial dysfunction and aging.
Topics: Aging; Diet, Protein-Restricted; Humans; Methionine; Mitochondria; Protein Biosynthesis; Proteins; Reactive Oxygen Species | 2008 |
Methionine+cystine requirement of broiler chickens fed low-density diets under tropical conditions.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cystine; Dietary Proteins; Dose-Response Relationship, Drug; Methionine; Nutritional Requirements; Nutritive Value; Random Allocation; Seasons; Tropical Climate; Weight Gain | 2009 |
Effect of BDNF val66met polymorphism on age-related amygdala volume changes in healthy subjects.
Topics: Adult; Aging; Amygdala; Analysis of Variance; Brain-Derived Neurotrophic Factor; Female; Genotype; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Polymorphism, Genetic; Regression Analysis; Valine | 2008 |
Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study.
Topics: Aged; Aging; Amino Acid Substitution; Angiotensinogen; Antihypertensive Agents; Depression; Family; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Threonine | 2008 |
The val158met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Atrophy; Catechol O-Methyltransferase; Female; Genotype; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Prefrontal Cortex; Regression Analysis; Valine; Young Adult | 2010 |
[In vivo effect of precursors of ubiquinone biosynthesis on sensitivity of mitochondrial permeability transition pore in the heart of old rats].
Topics: Aging; Animals; Arsenicals; Calcium; Male; Methionine; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardium; Parabens; Rats; Rats, Wistar; Ubiquinone; Vitamin E | 2008 |
The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy.
Topics: Aging; Animals; Diet, Vegetarian; Feeding Behavior; Humans; Life Expectancy; Methionine; Mice; Rats | 2009 |
Iron, ferritin and proteins of the methionine-centered redox cycle in young and old rat hearts.
Topics: Age Factors; Aging; Animals; Female; Ferritins; Gene Expression Regulation, Enzymologic; Iron; Methionine; Myocardium; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; RNA, Messenger; Thioredoxin-Disulfide Reductase; Thioredoxins | 2009 |
Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension.
Topics: Adolescent; Adult; Aged; Aging; Apolipoproteins E; Brain-Derived Neurotrophic Factor; Catechol O-Methyltransferase; Cognition; DNA Mutational Analysis; Female; Genotype; Humans; Hypertension; Inhibition, Psychological; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Sex Factors; Valine; Young Adult | 2009 |
Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair.
Topics: Aging; Catalase; Hair Color; Hair Follicle; Humans; Hydrogen Peroxide; Methionine; Oxidative Stress; Reactive Oxygen Species; Regeneration | 2009 |
Detection of oxidized methionine in selected proteins, cellular extracts and blood serums by novel anti-methionine sulfoxide antibodies.
Topics: Aging; Animals; Antibodies; Antibody Specificity; Blood Proteins; Cell Extracts; Humans; Methionine; Oxidation-Reduction; Oxidative Stress; Prions; Proteins; Serum | 2009 |
Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age.
Topics: Age Factors; Aging; Animals; Caloric Restriction; Diet, Vegetarian; Kaplan-Meier Estimate; Life Expectancy; Longevity; Male; Methionine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Proportional Hazards Models | 2009 |
[Expression of UCP3 and the sensitivity of mitochondrial permeability transition pore opening to Ca2+ in old rat heart under activation of biosynthesis of coenzyme Q].
Topics: Aging; alpha-Tocopherol; Animals; Biological Transport; Calcium; Intracellular Membranes; Ion Channel Gating; Ion Channels; Male; Methionine; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Mitochondrial Swelling; Myocardium; Oxidative Stress; Parabens; Rats; Rats, Wistar; Reactive Oxygen Species; Ubiquinone; Uncoupling Protein 3 | 2009 |
Ontogeny of methionine utilization and splanchnic uptake in critically ill children.
Topics: Abdomen; Adolescent; Aging; Algorithms; Carbon Dioxide; Child; Child, Preschool; Critical Illness; Diet; Enteral Nutrition; Female; Homocysteine; Humans; Infant; Isotope Labeling; Kinetics; Male; Methionine; Oxidation-Reduction | 2009 |
[Cardioprotective action of coenzyme Q in conditions of its endogenous synthesis activation in cardiac ischemia-reperfusion in old rats].
Topics: Aging; alpha-Tocopherol; Animals; Cardiotonic Agents; Coronary Circulation; Heart; Heart Function Tests; In Vitro Techniques; Male; Methionine; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Parabens; Rats; Rats, Wistar; Ubiquinone | 2009 |
Folic acid, vitamin B12, and homocysteine levels during fasting and after methionine load in patients with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Aging; Blood Glucose; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Sex Characteristics; Vitamin B 12; Young Adult | 2010 |
Ebbinghaus revisited: influences of the BDNF Val66Met polymorphism on backward serial recall are modulated by human aging.
Topics: Adult; Age Factors; Aged; Aging; Analysis of Variance; Brain-Derived Neurotrophic Factor; Chi-Square Distribution; Female; Genotype; Humans; Male; Mental Recall; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Serial Learning; Valine; Young Adult | 2010 |
Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aging; Autoimmune Diseases; CD27 Ligand; CD28 Antigens; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Male; Methionine; Micronutrients; Middle Aged; Receptors, KIR; T-Lymphocytes | 2010 |
BDNF modulates normal human hippocampal ageing [corrected].
Topics: Adult; Aged; Aged, 80 and over; Aging; Brain-Derived Neurotrophic Factor; Female; Genotype; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Memory; Methionine; Middle Aged; Neuropsychological Tests; Oxygen; Polymorphism, Genetic; Valine; Young Adult | 2010 |
Metabolic networks of longevity.
Topics: Aging; Amino Acids, Essential; Animals; Humans; Longevity; Metabolic Networks and Pathways; Methionine | 2010 |
Examination of 11C-methionine metabolism by the standardized uptake value in the normal brain of children.
Topics: Adolescent; Aging; Brain; Child; Child, Preschool; Female; Humans; Image Processing, Computer-Assisted; Infant; Infant, Newborn; Male; Methionine; Positron-Emission Tomography; Radiopharmaceuticals; Reference Values; Young Adult | 2011 |
Dietary restriction of amino acids other than methionine prevents oxidative damage during aging: involvement of telomerase activity and telomere length.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Amino Acids; Animals; Deoxyguanosine; Dietary Proteins; DNA Damage; DNA, Mitochondrial; Liver; Male; Methionine; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Reactive Oxygen Species; Telomerase; Telomere | 2012 |
Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria.
Topics: Aging; Animals; DNA, Mitochondrial; Male; Methionine; Mitochondria, Liver; Models, Animal; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; Reactive Oxygen Species; RNA-Binding Proteins; Sirtuin 1; Superoxide Dismutase; Transcription Factors | 2012 |
Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level.
Topics: Adult; Aging; Analysis of Variance; Brain-Derived Neurotrophic Factor; Depression; Female; Genetic Association Studies; Genotype; Humans; Life Style; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Sex Characteristics; Surveys and Questionnaires; Valine | 2012 |
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation.
Topics: Aging; Animals; Behavior, Animal; Benzamides; Cardiovascular Diseases; Drosophila melanogaster; Feeding Behavior; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Longevity; Male; Methionine; Mice; Simvastatin; Ubiquinone | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Can the beneficial effects of methionine restriction in rats be explained in part by decreased methylglyoxal generation resulting from suppressed carbohydrate metabolism?
Topics: Aging; Animals; Carbohydrate Metabolism; Dihydroxyacetone Phosphate; Foods, Specialized; Glyceraldehyde 3-Phosphate; Glycolysis; Longevity; Methionine; Mitochondria, Liver; Oxidative Stress; Protein Biosynthesis; Pyruvaldehyde; Rats; Reactive Oxygen Species | 2012 |
The Met-genotype of the BDNF Val66Met polymorphism is associated with reduced Stroop interference in elderly.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Brain Mapping; Brain-Derived Neurotrophic Factor; Electroencephalography; Evoked Potentials; Female; Gene Frequency; Genotype; Humans; Male; Mental Processes; Methionine; Neuropsychological Tests; Photic Stimulation; Polymorphism, Genetic; Reaction Time; Surveys and Questionnaires; Valine; Vocabulary | 2012 |
Impact of aging on the progression of neuropathy after liver transplantation in transthyretin Val30Met amyloidosis.
Topics: Adult; Aging; Amyloid Neuropathies, Familial; Humans; Liver Diseases; Liver Transplantation; Longitudinal Studies; Male; Methionine; Middle Aged; Prealbumin; Valine | 2012 |
Influence of age, sex and vitamin status on fasting and post-methionine load plasma homocysteine levels.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Fasting; Female; Homocysteine; Humans; Male; Methionine; Middle Aged; Sex Characteristics; Time Factors; Vitamins | 2002 |
Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila.
Topics: Aging; Alleles; Amino Acid Substitution; Animals; Animals, Genetically Modified; DNA Primers; Drosophila melanogaster; Glutathione; Humans; Life Expectancy; Methionine; Motor Neuron Disease; Mutagenesis, Site-Directed; Phenotype; Polymerase Chain Reaction; Superoxide Dismutase; Time Factors | 2003 |
Mitochondrial 5178A/C genotype is associated with acute myocardial infarction.
Topics: Aged; Aging; Alleles; Amino Acid Substitution; Diabetes Complications; DNA, Mitochondrial; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypercholesterolemia; Hypertension; Leucine; Male; Methionine; Middle Aged; Myocardial Infarction; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors | 2003 |
Polymorphism of the codon 129 of the prion protein (PrP) gene and neuropathology of cerebral ageing.
Topics: Aged; Aged, 80 and over; Aging; Amyloid beta-Peptides; Analysis of Variance; Brain; Chi-Square Distribution; Codon; DNA Mutational Analysis; Female; Genotype; Humans; Male; Methionine; Neurofibrillary Tangles; Plaque, Amyloid; Polymorphism, Genetic; Prions; tau Proteins; Valine | 2003 |
Altered methionine metabolism in long living Ames dwarf mice.
Topics: Aging; Animals; Brain; Cystathionine beta-Synthase; DNA Methylation; Glycine N-Methyltransferase; Liver; Male; Methionine; Methionine Adenosyltransferase; Methyltransferases; Mice; Mice, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 2003 |
Human beta-crystallins modified by backbone cleavage, deamidation and oxidation are prone to associate.
Topics: Adult; Aged; Aged, 80 and over; Aging; beta-Crystallin A Chain; beta-Crystallin B Chain; Child; Child, Preschool; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis, Gel, Two-Dimensional; Humans; Lens, Crystalline; Methionine; Middle Aged; Oxidation-Reduction; Protein Biosynthesis; Tryptophan | 2003 |
Age differences in the effects of L-cystine and DL-methionine on liver cholesterol storage in the rat.
Topics: Aging; Animals; Cholesterol; Cystine; Lipid Metabolism; Liver; Methionine; Rats | 1957 |
The part played by disulphide and methyl groups in ageing processes.
Topics: Aging; Cysteine; Cystine; Disulfides; Glutathione; Humans; Methionine | 1961 |
[S35]-methionine into the aorta of young and old bovine animals].
Topics: Aging; Animals; Aorta; Cattle; Methionine | 1961 |
Effect of methionine and age of rat on the occurrence of hemorrhagic diathesis in rats fed a ration containing irradiated beef.
Topics: Aging; Animals; Cattle; Diet; Female; Food Irradiation; Hemorrhagic Disorders; Humans; Meat; Methionine; Postpartum Hemorrhage; Postpartum Period; Rats | 1963 |
Effect of age on proteosynthesis in spinal motoneurons following nerveinterruption as shown by histoautoradiography of S35 labelled methionine.
Topics: Aging; Methionine; Motor Neurons; Neurons; Proteins; Spinal Cord | 1962 |
Functional development and intestinal absorption in the young poult.
Topics: Aging; Animal Feed; Animals; Fasting; Glucose; Intestinal Absorption; Intestine, Small; Male; Methionine; Oleic Acid; Poultry | 2003 |
Comparison of post-translational modifications of alpha A-crystallin from normal and hereditary cataract rats.
Topics: Aging; alpha-Crystallin A Chain; Animals; Aspartic Acid; Cataract; Disease Models, Animal; Humans; Isomerism; Lens, Crystalline; Methionine; Molecular Structure; Oxidation-Reduction; Peptides; Protein Processing, Post-Translational; Rats; Rats, Mutant Strains; Rats, Wistar; Time Factors | 2004 |
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocysteine; Humans; Life Style; Linear Models; Longitudinal Studies; Male; Methionine; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Sex Characteristics; Smoking; Tea; Vitamin B 12 | 2004 |
COMT gene polymorphism is associated with declarative memory in adulthood and old age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Catechol O-Methyltransferase; Humans; Male; Memory; Methionine; Middle Aged; Polymorphism, Genetic; Prefrontal Cortex; Valine | 2004 |
Effects of undernutrition on glycine metabolism in the cerebellum of rats.
Topics: Aging; Animals; Carbon Radioisotopes; Cerebellum; Dietary Proteins; Female; Glycine; Litter Size; Methionine; Nutrition Disorders; Organ Size; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar | 2004 |
Role of two angiotensinogen polymorphisms in blood pressure variation.
Topics: Aging; Alleles; Angiotensinogen; Blood Pressure; Diastole; Genotype; Ghana; Haplotypes; Humans; Methionine; Polymorphism, Genetic; Systole; Threonine | 2004 |
Defining the diet.
Topics: Aging; Animal Feed; Animals; Caloric Restriction; Diet; Female; Health Status; Humans; Longevity; Methionine; Mice; Nutritional Status | 2005 |
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance.
Topics: Acetaminophen; Aging; Alanine Transaminase; Animals; Blood Glucose; Body Weight; Cataract; Diet; Energy Intake; Female; Insulin; Insulin-Like Growth Factor I; Intramolecular Oxidoreductases; L-Lactate Dehydrogenase; Liver; Longevity; Macrophage Migration-Inhibitory Factors; Methionine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oxidative Stress; RNA, Messenger; T-Lymphocyte Subsets; Thyroxine | 2005 |
Purification and characterization of mouse hepatic enzyme that converts selenomethionine to methylselenol by its alpha,gamma-elimination.
Topics: Aging; Ammonium Sulfate; Animals; Brain; Carbon-Sulfur Lyases; Catalysis; Chromatography; Female; Homocysteine; Homoserine; Humans; Intestine, Large; Kinetics; Liver; Male; Methanol; Methionine; Mice; Mice, Inbred ICR; Muscles; Organoselenium Compounds; Selenium; Selenomethionine; Substrate Specificity; Temperature | 2005 |
Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse.
Topics: Aging; Animals; Antioxidants; Brain; Chromatography, High Pressure Liquid; Cysteine; Diet; Female; Glutathione; Glutathione Disulfide; Kidney; Liver; Male; Methionine; Mice; Mitochondria; Muscle, Skeletal; Myocardium; Oxidation-Reduction | 2005 |
Increased sensitivity of amino-arm truncated betaA3-crystallin to UV-light-induced photoaggregation.
Topics: Aging; Animals; Baculoviridae; beta-Crystallin A Chain; Blotting, Western; Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Gene Expression; Light; Methionine; Mice; Oxidation-Reduction; Photochemistry; Photolysis; Protein Denaturation; Recombinant Proteins; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultraviolet Rays | 2005 |
Differential degradation of ferritin H- and L-chains: accumulation of L-chain-rich ferritin in lens epithelial cells.
Topics: Aging; Animals; Apoferritins; Cells, Cultured; Cysteine Proteinase Inhibitors; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Ferritins; Iron; Lens, Crystalline; Lysosomes; Methionine; Plasmids; Transfection | 2005 |
Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress.
Topics: Aging; Antigens, Polyomavirus Transforming; Cell Line; Cell Survival; DNA, Complementary; Dose-Response Relationship, Drug; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Immunoblotting; Methionine; Methionine Sulfoxide Reductases; Microscopy, Fluorescence; Oxidative Stress; Oxidoreductases; Oxygen; Proteins; Reactive Oxygen Species; Transfection | 2005 |
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; DNA Methylation; Early Growth Response Protein 1; Epigenesis, Genetic; Female; Hippocampus; Hypothalamo-Hypophyseal System; Maternal Behavior; Methionine; Pituitary-Adrenal System; Promoter Regions, Genetic; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Stress, Physiological | 2005 |
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.
Topics: Aging; Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Diet; Enzyme Induction; Gene Expression Regulation, Developmental; Growth and Development; Lipoproteins, VLDL; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; RNA Stability; RNA, Messenger; Sterol Regulatory Element Binding Proteins; Transcription, Genetic | 2006 |
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination | 2006 |
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood.
Topics: Aging; Animals; Anxiety; Behavior, Animal; Cell Adhesion Molecules, Neuronal; DNA Helicases; Extracellular Matrix Proteins; Gene Expression Regulation; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Maternal Behavior; Methionine; Mothers; Nerve Tissue Proteins; Proteins; Rats; Reelin Protein; Serine Endopeptidases; Transcription, Genetic | 2006 |
Stress resistance and aging: influence of genes and nutrition.
Topics: Acetaminophen; Aging; Animals; Cadmium; Caloric Restriction; Cell Line; Diet; Dwarfism; Female; Fibroblasts; Hydrogen Peroxide; Longevity; Male; Methionine; Mice; Mice, Knockout; Receptors, Somatotropin; Skin; Ultraviolet Rays | 2006 |
Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction.
Topics: Adipose Tissue; Adiposity; Aging; Animals; Body Composition; Body Weight; Cholesterol; Energy Intake; Energy Metabolism; Glucose Tolerance Test; Insulin; Insulin-Like Growth Factor I; Male; Methionine; Rats; Rats, Inbred F344; Time Factors; Triglycerides | 2006 |
Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse.
Topics: Aging; Amyloid beta-Peptides; Animals; Astrocytes; Cell Survival; Drug Resistance; Free Radicals; Glial Fibrillary Acidic Protein; Hippocampus; Hydrogen Peroxide; Methionine; Methionine Sulfoxide Reductases; Mice; Mice, Knockout; Models, Biological; Neurodegenerative Diseases; Neurons; Organ Culture Techniques; Oxidative Stress; Oxidoreductases; Protein Folding; Species Specificity; Synaptophysin; tau Proteins; Up-Regulation | 2007 |
Methionine sulfoxide reduction and the aging process.
Topics: Aging; Antioxidants; Cysteine; Gene Deletion; Methionine; Methionine Sulfoxide Reductases; Models, Genetic; Oxidative Stress; Oxidoreductases; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Time Factors | 2007 |
COMT genotype and cognitive ability: a longitudinal aging study.
Topics: Aged; Aging; Analysis of Variance; Catechol O-Methyltransferase; Cognition; Confidence Intervals; Female; Genotype; Humans; Intelligence Tests; Longitudinal Studies; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Single Nucleotide; Retrospective Studies; Valine | 2007 |
[Protein synthesis and the regulation process in the cell].
Topics: Aging; Animals; Arginine; Autoradiography; Axons; Body Weight; Cell Biology; Cytoplasmic Granules; Glycine; Golgi Apparatus; Guinea Pigs; Hippocampus; Homeostasis; Leucine; Methionine; Mice; Microscopy, Electron; Neurons; Pancreas; Photoreceptor Cells; Protein Biosynthesis; Purkinje Cells; Pyramidal Tracts; Rats; Ribosomes; RNA; RNA, Messenger; Spectrophotometry; Thyroid Gland; Time Factors; Tritium; Tyrosine | 1966 |
Influence of age on monoamine oxidase and catechol-O-methyltransferase in rat tissues.
Topics: Aging; Animals; Brain; Carbon Isotopes; Epinephrine; Female; In Vitro Techniques; Indoleacetic Acids; Liver; Male; Methionine; Monoamine Oxidase; Myocardium; Nucleosides; Rats; Transferases; Tryptamines | 1967 |
Autoradiographic study of protein metabolism in old and adolescent neurones.
Topics: Aging; Animals; Autoradiography; Kinetics; Methionine; Motor Neurons; Protein Biosynthesis; Rats; Spinal Cord; Sulfur Isotopes | 1967 |
Selective increase in cytokeratin synthesis in cultured rat hepatocytes in response to hormonal stimulation.
Topics: Aging; Animals; Dexamethasone; Epidermal Growth Factor; In Vitro Techniques; Insulin; Keratins; Liver; Methionine; Molecular Weight; Proteins; Rats; Rats, Inbred F344 | 1983 |
Developmental changes in protein carboxylmethylation and in the benzodiazepine receptor proteins in rat brain.
Topics: Aging; Animals; Benzodiazepines; Brain; Cell Membrane; Flunitrazepam; Kinetics; Male; Methionine; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Beta-adrenergic control of phosphatidylcholine synthesis by transmethylation in hepatocytes from juvenile, adult and adrenalectomized rats.
Topics: Adrenalectomy; Aging; Animals; Cyclic AMP; Ethanolamines; In Vitro Techniques; Insulin; Isoproterenol; Liver; Male; Methionine; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Propranolol; Rats; Rats, Inbred Strains | 1983 |
Developmental changes in the metabolism of 3-methylthiopropionate in the rat.
Topics: Aging; Animals; Liver; Male; Methionine; Oxygen Consumption; Propionates; Rats; Sulfur | 1984 |
Investigations of in vivo methionine racemization in mammalian tissues.
Topics: Aging; Animals; Aspartic Acid; Chromatography, Gas; Dentin; Hydrogen-Ion Concentration; Kinetics; Lens, Crystalline; Macaca mulatta; Methionine; Stereoisomerism | 1984 |
The effect of dietary methionine on the copper content of tissues and survival of young and old mice.
Topics: Aging; Animals; Body Weight; Brain; Copper; Diet; Longevity; Male; Methionine; Mice; Mice, Inbred C57BL; Tissue Distribution | 1984 |
Tissue metabolism of methionine in sheep.
Topics: Aging; Animals; Carbon Radioisotopes; Female; Intestinal Mucosa; Intestine, Small; Kidney Cortex; Liver; Male; Methionine; Muscles; Organ Specificity; Pancreas; Sheep; Species Specificity | 1983 |
Olfactory marker protein: turnover and transport in normal and regenerating neurons.
Topics: Aging; Animals; Epithelium; Female; Kinetics; Methionine; Mice; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Octoxynol; Olfactory Bulb; Olfactory Marker Protein; Olfactory Nerve; Polyethylene Glycols; Sulfur Radioisotopes | 1984 |
Alterations in immune function in rats caused by dietary lipotrope deficiency: effect of age.
Topics: Aging; Animals; Cells, Cultured; Choline Deficiency; Folic Acid Deficiency; Immunocompetence; Lymph Nodes; Lymphocyte Activation; Male; Methionine; Rats; Rats, Inbred Strains; Salmonella Infections; Salmonella typhimurium; Spleen; Thymus Gland | 1982 |
Digestion in the pigs between 7 and 35 d of age. 4. The digestion of amino acids in pigs given milk and soya-bean proteins.
Topics: Aging; Amino Acids; Animals; Dietary Proteins; Digestion; Glycine max; Ileum; Intestine, Small; Lysine; Methionine; Milk Proteins; Plant Proteins; Swine | 1981 |
The effect of age on the initiation of protein synthesis in Drosophila melanogaster.
Topics: Aging; Animals; Centrifugation, Density Gradient; Drosophila melanogaster; Methionine; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; RNA, Transfer, Amino Acyl | 1981 |
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine | 1982 |
Age-related changes in different steps of protein synthesis of liver and kidney of rats.
Topics: Aging; Animals; Kidney; Kinetics; Liver; Male; Methionine; Organ Specificity; Phenylalanine; Protein Biosynthesis; Proteins; Puromycin; Rats; Rats, Inbred Strains | 1983 |
Methotrexate effects on hepatic betaine levels in choline-supplemented and choline-deficient rats.
Topics: Aging; Animals; Betaine; Choline; Choline Deficiency; Liver; Male; Methionine; Methotrexate; Rats; Rats, Inbred Strains | 1982 |
Selective oxidation of cysteine and methionine in normal and senile cataractous lenses.
Topics: Aged; Aging; Cataract; Crystallins; Cysteine; Humans; Lens, Crystalline; Membrane Proteins; Methionine; Middle Aged; Oxidation-Reduction | 1980 |
Enhancement of the responsiveness of the rat diaphragm by L-methionine and phospholipid methylation and their relationships to aging.
Topics: Adenosine; Aging; Animals; Diaphragm; Electric Stimulation; Methionine; Methyltransferases; Muscle, Smooth; Phospholipids; Phrenic Nerve; Rats; Rats, Inbred F344 | 1982 |
A note on the amino acid composition of the turkey.
Topics: Aging; Amino Acids; Animals; Autoanalysis; Body Composition; Chickens; Cystine; Feathers; Geese; Male; Methionine; Proteins; Species Specificity; Tryptophan; Turkeys | 1982 |
Sources and turnover rates of taurine in newborn, weanling, and mature rats.
Topics: Aging; Animals; Animals, Newborn; Dietary Proteins; Female; Fetus; Half-Life; Male; Maternal-Fetal Exchange; Methionine; Pregnancy; Rats; Taurine; Tissue Distribution; Weaning | 1981 |
Influence of exogenous L-3,4,-dihydroxyphenylalanine (L-dopa) on the methionine and s-adenosylmethionine concentrations in the brain and other tissues [proceedings].
Topics: Aging; Animals; Brain; Iproniazid; Kidney; Levodopa; Liver; Methionine; Organ Specificity; Rats; S-Adenosylmethionine | 1980 |
Developmental changes in polypeptide composition of, and precursor incorporation into, cellular and subcellular fractions of rat cerebral cortex.
Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Female; Male; Methionine; Molecular Weight; Nerve Tissue Proteins; Neuroglia; Neurons; Peptides; Rats; Subcellular Fractions | 1981 |
The temporal relationships of synthesis and phosphorylation in stress proteins 70 and 90 in aged caloric restricted rats exposed to bleomycin.
Topics: Aging; Animals; Bleomycin; Energy Intake; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Male; Methionine; Phosphoric Acids; Phosphorus Radioisotopes; Phosphorylation; Rats; Rats, Inbred F344; Sulfur Radioisotopes; Time Factors | 1994 |
Effect of cysteine on expression of cystathionine beta-synthase in the rat liver.
Topics: Aging; Animals; Base Sequence; Cystathionine beta-Synthase; Cysteine; DNA Primers; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Age-specific alterations in muscarinic stimulation of K(+)-evoked dopamine release from striatal slices by cholesterol and S-adenosyl-L-methionine.
Topics: Aging; Animals; Cholesterol; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; GTP Phosphohydrolases; Methionine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction | 1995 |
Effect of age on seminiferous tubule protein secretion and the adverse effects of testicular toxicants in the rat.
Topics: Aging; Animals; Cells, Cultured; Culture Techniques; Dinitrobenzenes; Electrophoresis, Polyacrylamide Gel; Follicle Stimulating Hormone; Male; Methionine; Nitrobenzenes; Proteins; Rats; Rats, Sprague-Dawley; Seminiferous Tubules; Testis | 1993 |
Effect of interleukin 1 on articular cartilage from young and aged horses and comparison with metabolism of osteoarthritic cartilage.
Topics: Aging; Animals; Animals, Newborn; Cartilage, Articular; Electrophoresis, Polyacrylamide Gel; Horse Diseases; Horses; Humans; Interleukin-1; Metalloendopeptidases; Methionine; Organ Culture Techniques; Osteoarthritis; Peptide Hydrolases; Protein Biosynthesis; Proteins; Proteoglycans; Recombinant Proteins; Sulfates; Sulfur Radioisotopes | 1994 |
Simultaneous racemization and isomerization at specific aspartic acid residues in alpha B-crystallin from the aged human lens.
Topics: Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Amino Acids; Aspartic Acid; Crystallins; Humans; Infant; Isomerism; Methionine; Molecular Sequence Data; Oxidation-Reduction; Peptides; Stereoisomerism; Trypsin | 1994 |
Synthesis, characterization and hormonal regulation of epididymal proteins during postnatal development of the mouse.
Topics: Aging; Animals; Electrophoresis, Polyacrylamide Gel; Epididymis; Male; Methionine; Mice; Molecular Weight; Orchiectomy; Protein Biosynthesis; Proteins; Reference Values; Sexual Maturation; Testis | 1994 |
Cloning of cDNA for the alpha subunit of mouse insulin-like growth factor I receptor and the role of the receptor in metanephric development.
Topics: Aging; Amino Acid Sequence; Animals; Autoradiography; Base Sequence; Cloning, Molecular; DNA, Complementary; Female; Gene Library; Gestational Age; Kidney; Macromolecular Substances; Methionine; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Organ Culture Techniques; Pregnancy; Receptor, IGF Type 1; Sulfur Radioisotopes | 1993 |
Characterization of macromolecule resonances in the 1H NMR spectrum of rat brain.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain Chemistry; Chromatography, Gel; Cytosol; Female; Hydrogen; Image Enhancement; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Methionine; Myelin Sheath; Proteins; Rats; Rats, Sprague-Dawley | 1993 |
High levels of quinolinic acid in brain of epilepsy-prone E1 mice.
Topics: Aging; Amino Acids; Animals; Cerebral Cortex; Epilepsy; Escherichia coli; Lipopolysaccharides; Methionine; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Quinolinic Acid; Species Specificity; Threonine; Tryptophan | 1993 |
The effect of age on the synthesis of two heat shock proteins in the hsp70 family.
Topics: Actins; Aging; Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hot Temperature; Immunoglobulin Heavy Chains; Liver; Male; Methionine; Molecular Chaperones; Molecular Weight; Rats; Rats, Inbred F344; Sulfur Radioisotopes; Time Factors | 1993 |
Effects of dietary sulfur amino acids and crude protein on the performance of finishing broilers.
Topics: Aging; Animal Feed; Animals; Body Weight; Chickens; Cystine; Dietary Proteins; Digestion; Energy Intake; Food, Fortified; Male; Methionine; Weight Gain | 1995 |
Dexamethasone enhanced by insulin, but not by thyroid hormones stimulates apolipoprotein B mRNA editing in cultured rat hepatocytes depending on the developmental stage.
Topics: Aging; Animals; Animals, Newborn; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Cells, Cultured; Dexamethasone; DNA Primers; Drug Interactions; Drug Synergism; Fetus; Gene Expression Regulation, Developmental; Hyperthyroidism; Insulin; Liver; Methionine; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA Editing; RNA, Messenger; Triiodothyronine | 1996 |
Uptake capacity in vitro for glucose and methionine and in situ for oleic acid in the proximal small intestine of posthatch chicks.
Topics: Aging; Animals; Chickens; Duodenum; Glucose; In Vitro Techniques; Intestine, Small; Inulin; Jejunum; Methionine; Oleic Acid | 1996 |
Modification of protein surface hydrophobicity and methionine oxidation by oxidative systems.
Topics: Aging; Animals; Methionine; Oxidation-Reduction; Proteins; Rats; Rats, Inbred F344; Tryptophan; Tyrosine | 1997 |
Are dietary factors involved in DNA methylation associated with colon cancer?
Topics: Aged; Aging; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Pyridoxine; Retrospective Studies; Risk Factors; Vitamin B 12 | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Evaluation of protein and energy quality of rendered spent hen meals.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Energy Intake; Lysine; Male; Methionine; Nutritive Value | 1997 |
Progressive decline in the ability of calmodulin isolated from aged brain to activate the plasma membrane Ca-ATPase.
Topics: Aging; Amino Acid Sequence; Animals; Brain Chemistry; Calcium; Calcium-Transporting ATPases; Calmodulin; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythrocyte Membrane; Mass Spectrometry; Methionine; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Rats; Rats, Inbred F344; Spectrometry, Fluorescence; Swine; Thermodynamics; Tryptophan; Tyrosine | 1998 |
Yolk utilisation in the newly hatched poult.
Topics: Aging; Animals; Chickens; Digestion; Duodenum; Egg Yolk; Fatty Acids, Nonesterified; Gizzard, Avian; Glucose; Intestinal Absorption; Intestine, Small; Lipolysis; Methionine; Oleic Acid; Time Factors | 1998 |
Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase.
Topics: Aging; Amino Acid Sequence; Animals; Brain; Calcium-Transporting ATPases; Calmodulin; Cell Membrane; Chromatography, High Pressure Liquid; Enzyme Activation; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Peptide Fragments; Protein Folding; Protein Isoforms; Rats; Rats, Inbred F344; Trypsin | 1999 |
Diastereoselective reduction of protein-bound methionine sulfoxide by methionine sulfoxide reductase.
Topics: Aging; Amino Acid Sequence; Animals; Calmodulin; Cattle; In Vitro Techniques; Methionine; Methionine Sulfoxide Reductases; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Binding; Recombinant Proteins; Stereoisomerism; Substrate Specificity | 1999 |
Sex steroids modulate the synthesis and phosphorylation of proteins in the brain cortex of aging mice.
Topics: Aging; Animals; Cerebral Cortex; Estradiol; Female; In Vitro Techniques; Male; Methionine; Mice; Mice, Inbred AKR; Phosphates; Phosphorylation; Protein Biosynthesis; Proteins; Testosterone | 1999 |
Effects of methionine-induced hyperhomocysteinemia on endothelium-dependent vasodilation and oxidative status in healthy adults.
Topics: Adult; Aged; Aging; Endothelium, Vascular; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Oxidation-Reduction; Prospective Studies; Vasodilation | 2000 |
C-terminal phosphorylation of the high molecular weight neurofilament subunit correlates with decreased neurofilament axonal transport velocity.
Topics: Aging; Animals; Autoradiography; Axonal Transport; Axons; Carrier Proteins; Cytoskeleton; Macromolecular Substances; Methionine; Mice; Microfilament Proteins; Neurofilament Proteins; Optic Nerve; Phosphorylation; Retina; Retinal Ganglion Cells; Sulfur Radioisotopes; Visual Pathways | 2000 |
Identification of limiting amino acids in methionine- and lysine-supplemented low-protein diets for turkeys.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Diet, Protein-Restricted; Dietary Supplements; Glycine max; Lysine; Male; Meat; Methionine; Nutritional Requirements; Turkeys; Weight Gain; Zea mays | 2000 |
Hoxa-5 in mouse developing lung: cell-specific expression and retinoic acid regulation.
Topics: Aging; Animals; Animals, Newborn; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Gestational Age; Homeodomain Proteins; Kinetics; Lung; Male; Methionine; Mice; Phosphoproteins; Respiratory Mucosa; Sex Characteristics; Transcription Factors; Transcription, Genetic; Tretinoin; Uridine | 2000 |
Interaction between ambient temperature and supplementation of synthetic amino acids on performance and carcass parameters in commercial male turkeys.
Topics: Aging; Amino Acids; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Body Weight; Diet; Eating; Lysine; Male; Meat; Methionine; Temperature; Threonine; Turkeys; Weight Gain | 2000 |
Intestinal transport of monosaccharides and amino acids during postnatal development of mink.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Body Weight; Female; Fructose; Glucose; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Lysine; Male; Methionine; Microvilli; Mink; Monosaccharides; Proline | 2000 |
Simultaneous determination of total plasma glutathione, homocysteine, cysteinylglycine, and methionine by high-performance liquid chromatography with electrochemical detection.
Topics: Aging; Calibration; Chromatography, High Pressure Liquid; Diabetes Mellitus; Dipeptides; Female; Glutathione; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Quality Control; Reference Values; Risk Factors; Sensitivity and Specificity | 2001 |
Yolk and exogenous feed utilization in the posthatch chick.
Topics: Aging; Animal Feed; Animals; Chickens; Egg Yolk; Energy Intake; Glucose; Intestinal Absorption; Male; Methionine; Oleic Acid | 2001 |
Ocular findings among patients with late-diagnosed or poorly controlled homocystinuria compared with a screened, well-controlled population.
Topics: Adult; Aging; Astigmatism; Child; Child, Preschool; Cystine; Disease Progression; Female; Homocystine; Homocystinuria; Humans; Infant; Lens Subluxation; Male; Methionine; Myopia; Time Factors; Visual Acuity; Vitamin B 6 | 2001 |
Hyperhomocysteinemia and related factors in 600 hospitalized elderly subjects.
Topics: Aged; Aged, 80 and over; Aging; Dementia; Diabetes Complications; Fasting; Female; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Kinetics; Linear Models; Male; Methionine; Nutrition Disorders; Odds Ratio; Renal Insufficiency; Vascular Diseases | 2001 |
High dietary folate supplementation: effects on diet utilization and methionine metabolism in aged rats.
Topics: Aging; Analysis of Variance; Animals; Biomarkers; Dietary Fats; Dietary Proteins; Dietary Supplements; DNA Methylation; Folic Acid; Male; Methionine; Rats; Rats, Wistar | 2002 |
The rate of Tau synthesis is differentially regulated during postnatal development in mouse cerebellum.
Topics: Aging; Animals; Animals, Newborn; Calcineurin; Cerebellum; Gene Expression Regulation, Developmental; Methionine; Mice; Phosphoprotein Phosphatases; Protein Isoforms; Sulfur Radioisotopes; Synapses; tau Proteins | 2001 |
Methionine supply to growing steers affects hepatic activities of methionine synthase and betaine-homocysteine methyltransferase, but not cystathionine synthase.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Amino Acids; Animals; Betaine-Homocysteine S-Methyltransferase; Cattle; Cystathionine beta-Synthase; Liver; Male; Methionine; Methyltransferases; Nitrogen; Osmolar Concentration | 2002 |
Isolation and identification of urinary beta-aspartyl dipeptides and their concentrations in human urine.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Child; Dipeptides; Female; Glutamates; Glycine; Humans; Hydrogen-Ion Concentration; Male; Methionine; Middle Aged; Neoplasms; Parenteral Nutrition, Total; Sex Factors; Threonine; Uremia | 1978 |
Rapid axoplasmic transport in dystrophic mice.
Topics: Aging; Animals; Axonal Transport; Female; In Vitro Techniques; Methionine; Mice; Muscular Dystrophy, Animal; Nerve Tissue Proteins; Proline; Sciatic Nerve; Species Specificity; Spinal Cord | 1977 |
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine | 1979 |
Studies on ageing of collagen by perchlorate reactions.
Topics: Aging; Aldehydes; Animals; Collagen; Elasticity; Methionine; Perchlorates; Rats; Tendons | 1975 |
Kinetics of methionine influx into various regions of chicken intestine.
Topics: Aging; Amino Acids; Animals; Biological Transport; Cecum; Chickens; Colon; Duodenum; Female; Ileum; Intestinal Mucosa; Intestines; Jejunum; Kinetics; Male; Mannitol; Methionine | 1975 |
Effects of early marginal methionine-choline deprivation on the development of the immune system in the rat.
Topics: Agglutination Tests; Aging; Animals; Antibody Formation; Choline Deficiency; Female; Hypersensitivity, Delayed; Immunity, Cellular; Lactation; Lymphocytes; Male; Maternal-Fetal Exchange; Methionine; Mitogens; Pregnancy; Pregnancy Complications; Rats; Salmonella Infections; Salmonella typhimurium | 1979 |
Protein degradation in aged nematodes (Turbatrix aceti).
Topics: Aging; Animals; Kinetics; Methionine; Nematoda; Proteins | 1979 |
Studies of ethylene-forming system in rat liver extract.
Topics: Aging; Animals; Ethylenes; Female; In Vitro Techniques; Liver; Male; Methionine; Rats | 1979 |
Base composition changes in hepatocyte nuclei DNA of rats at different ages.
Topics: Aging; Animals; Animals, Newborn; Cell Nucleus; Centrifugation, Density Gradient; Deoxyribonucleosides; DNA; Hydroxyapatites; Liver; Methionine; Nucleic Acid Denaturation; Temperature; Thymidine | 1978 |
Renal excretion of cystathionine and creatinine in humans at different ages.
Topics: Adolescent; Adult; Aging; Body Surface Area; Child; Child, Preschool; Creatinine; Cystathionine; Diet; Humans; Infant; Infant Food; Infant, Newborn; Infant, Premature; Methionine; Middle Aged | 1978 |
Methionine metabolism in mammals: regulation of methylenetetrahydrofolate reductase content of rat tissues.
Topics: Aging; Animals; Brain; Dietary Proteins; Kidney; Liver; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Oxidoreductases; Rats; Spleen; Subcellular Fractions; Tissue Distribution | 1978 |
Gas chromatographic-mass spectrometric identification of epinine in rat superior cervical ganglia and formation in vivo.
Topics: Aging; Animals; Animals, Newborn; Chromatography, Gas; Deoxyepinephrine; Dopamine; Epinephrine; Ganglia, Spinal; Mass Spectrometry; Methionine; Norepinephrine; Rats | 1977 |
[Ageing changes in collagen -- in vitro ageing changes in collagen (part III) (author's transl)].
Topics: Aged; Aging; Collagen; Connective Tissue; Fibroblasts; Humans; Methionine | 1976 |
Altered protein hypothesis of mammalian ageing processes-II. Discrimination ratio of methionine vs ethionine in the synthesis of ribosomal protein and RNA of C57BL/6J mouse liver.
Topics: Age Factors; Aging; Animals; Carbon Radioisotopes; Electrophoresis, Polyacrylamide Gel; Ethionine; Female; Liver; Methionine; Methionine Adenosyltransferase; Methionine-tRNA Ligase; Methylation; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Weight; Proteins; Ribosomal Proteins; RNA, Ribosomal; Tritium | 1975 |
Phospholipid methylation and taurine content of synaptosomes from cerebral cortex of developing rat.
Topics: Aging; Animals; Cerebral Cortex; Male; Methionine; Methylation; Phospholipids; Rats; Synaptosomes; Taurine; Tritium | 1992 |
Changes in rapidly transported proteins associated with development of abnormal projections in the diencephalon.
Topics: Aging; Animals; Autoradiography; Axonal Transport; Axons; Blotting, Western; Brain Injuries; Cell Adhesion Molecules, Neuronal; Cricetinae; Diencephalon; GAP-43 Protein; Geniculate Bodies; Horseradish Peroxidase; Membrane Glycoproteins; Mesocricetus; Methionine; Molecular Weight; Nerve Tissue Proteins; Retina; Retinal Ganglion Cells; Sulfur Radioisotopes; Superior Colliculi; Thalamus | 1992 |
Intermediate filament protein expression in differentiating Schwann cells.
Topics: Aging; Animals; Cell Differentiation; Cells, Cultured; Embryo, Mammalian; Intermediate Filament Proteins; Methionine; Molecular Weight; Rats; Schwann Cells; Sciatic Nerve | 1992 |
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Pyridoxal Phosphate; Sex Characteristics; Vascular Diseases; Vitamin B 12 | 1992 |
Regulation of tyrosinase in hair follicular melanocytes of the mouse during the synthesis of eumelanin and phaeomelanin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Cyclic AMP; Female; Glycosylation; Hair; Homeostasis; Kinetics; Male; Melanins; Melanocytes; Methionine; Mice; Mice, Inbred C3H; Monophenol Monooxygenase; RNA, Messenger; Sexual Maturation; Tunicamycin | 1991 |
Golgi sulfation of the oligosaccharide chain of P0 occurs in the presence of myelin assembly but not in its absence.
Topics: Aging; Alkaloids; Animals; Golgi Apparatus; Kinetics; Male; Mannosidases; Membrane Glycoproteins; Methionine; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Oligosaccharides; Peripheral Nerves; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Sciatic Nerve; Sulfates; Swainsonine | 1990 |
Thyroxine and cortisone cooperate to modulate postnatal intestinal enzyme differentiation in the rat.
Topics: Aging; Animals; Animals, Newborn; beta-Galactosidase; Cortisone; Enzyme Induction; Immunoelectrophoresis; Intestinal Mucosa; Jejunum; Kinetics; Lactase; Methionine; Rats; Rats, Inbred Strains; Reference Values; Sucrase; Sulfur Radioisotopes; Thyroxine | 1991 |
L-methionine uptake by human cerebral cortex: maturation from infancy to old age.
Topics: Adult; Aged; Aging; Biological Transport; Brain; Brain Neoplasms; Carbon Radioisotopes; Cerebral Cortex; Child; Child, Preschool; Humans; Infant; Methionine; Tomography, Emission-Computed | 1991 |
Detection of secreted and temporarily inducible heat shock responsive proteins in mouse testicular tissue.
Topics: Aging; Animals; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Hot Temperature; Male; Methionine; Mice; Mice, Inbred C57BL; Molecular Weight; Seminiferous Tubules; Sulfur Radioisotopes; Testis | 1991 |
Increased levels of oxidized methionine residues in bronchoalveolar lavage fluid proteins from patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aging; Bronchoalveolar Lavage Fluid; Drug Residues; Female; Humans; Leukocyte Count; Lymphocytes; Male; Methionine; Middle Aged; Neutrophils; Oxidation-Reduction; Proteins; Pulmonary Fibrosis; Reference Values; Sarcoidosis | 1991 |
Angiotensin II induces secretion of plasminogen activator inhibitor 1 and a tissue metalloprotease inhibitor-related protein from rat brain astrocytes.
Topics: Aging; Amino Acid Sequence; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glycoproteins; Kinetics; Methionine; Molecular Sequence Data; Molecular Weight; Nerve Tissue Proteins; Plasminogen Inactivators; Rats; Sequence Homology, Nucleic Acid; Sulfur Radioisotopes; Tissue Inhibitor of Metalloproteinases | 1991 |
Intestinal lactase in the neonatal rat. Maturational changes in intracellular processing and brush-border degradation.
Topics: Aging; Animals; Animals, Newborn; beta-Galactosidase; Galactosidases; Intestine, Small; Kinetics; Lactase; Macromolecular Substances; Methionine; Microvilli; Molecular Weight; Muscle Development; Muscle, Smooth; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains | 1990 |
Cerebrospinal fluid concentrations of S-adenosylmethionine, methionine, and 5-methyltetrahydrofolate in a reference population: cerebrospinal fluid S-adenosylmethionine declines with age in humans.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Methionine; S-Adenosylmethionine; Tetrahydrofolates | 1990 |
Differential synthesis of crystallins in the developing rat eye lens.
Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; Crystallins; Electrophoresis, Gel, Two-Dimensional; Lens, Crystalline; Methionine; Molecular Sequence Data; Peptide Mapping; Rats; Rats, Inbred Strains; Sulfur Radioisotopes | 1990 |
Changes with aging in the levels of amino acids in rat CNS structural elements: IV. Methionine and basic amino acids.
Topics: Aging; Amino Acids; Animals; Brain; Male; Methionine; Rats; Rats, Inbred F344 | 1990 |
Age-related changes in glutathione synthesis in the eye lens.
Topics: Acetylcysteine; Adenosine Triphosphate; Aging; Animals; Cystathionine gamma-Lyase; Glutathione; Lens, Crystalline; Methionine; Mice; Oxidation-Reduction; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide | 1990 |
Studies on myelin-basic-protein methylation during mouse brain development.
Topics: Aging; Amino Acids; Animals; Brain; Electrophoresis, Polyacrylamide Gel; Leucine; Methionine; Methylation; Mice; Mice, Inbred Strains; Myelin Basic Protein | 1986 |
Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.
Topics: Aging; Animals; Arginine; Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Histidine; Immunosorbent Techniques; Liver; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1989 |
Cultured human foreskin fibroblasts produce a factor that stimulates their growth with properties similar to basic fibroblast growth factor.
Topics: Aging; Autoradiography; Cell Division; Cells, Cultured; Fibroblast Growth Factors; Fibroblasts; Humans; Immune Sera; Infant, Newborn; Male; Methionine; Precipitin Tests; Sulfur Radioisotopes | 1989 |
O6-methylguanine-DNA methyltransferase levels in tissues of methionine-cysteine deficient subadult and adult mice.
Topics: Aging; Animals; Cysteine; Male; Methionine; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Organ Size | 1988 |
Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate.
Topics: Aging; Animals; Butyrates; Butyric Acid; Chromatin; High Mobility Group Proteins; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Spermine | 1989 |
Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.
Topics: Aging; Animals; Arginine; Histidine; Kinetics; Liver; Lysine; Malate Dehydrogenase; Methionine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds | 1988 |
Effects of ingestion of high protein or excess methionine diets by rats for two years.
Topics: Aging; Animals; Arteries; Body Weight; Caseins; Dietary Proteins; Fibrosis; Hypertrophy; Male; Methionine; Organ Size; Rats; Rats, Inbred Strains | 1988 |
Age dependent changes in the expression of Drosophila mitochondrial proteins.
Topics: Aging; Animals; Drosophila; Electrophoresis, Polyacrylamide Gel; Methionine; Mitochondria; Protein Biosynthesis; Proteins; Sulfur Radioisotopes | 1986 |
Protein synthesis activity in vitro in mouse tissues in relation to methionine-cysteine deficiency and age.
Topics: Aging; Animals; Cysteine; DNA; Kidney; Liver; Lung; Male; Methionine; Mice; Polyribosomes; Protein Biosynthesis; RNA, Ribosomal | 1986 |
Sarcolemmal phospholipid N-methylation in genetically determined hamster cardiomyopathy.
Topics: Aging; Animals; Cardiomyopathies; Cricetinae; Heart; Kinetics; Mesocricetus; Methionine; Methylation; Myocardium; Phosphatidylethanolamines; Sarcolemma; Species Specificity; Tritium | 1987 |
Folic acid responsive postmenopausal homocysteinemia.
Topics: Adult; Aging; Cystine; Dipeptides; Fasting; Female; Folic Acid; Glycine; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Serine | 1985 |
Age-related changes in turnover and concentration of a subset of thorax polypeptides from Drosophila melanogaster.
Topics: Aging; Animals; Autoradiography; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Humans; Methionine; Peptides; Sulfur Radioisotopes; Thorax | 1985 |
Methionine-cysteine deficiency and alkylation of DNA in liver, kidney and lung of mice administered dimethylnitrosamine.
Topics: Aging; Alkylation; Animals; Cysteine; Diet; Dimethylnitrosamine; DNA; Kidney; Liver; Lung; Male; Methionine; Methylation; Mice; Purines | 1985 |
[Effects of dietary surcharges of DL-methionine and DL-serine adminisitered alone or in combination on the development of mono and binucleated rat pancreas cells].
Topics: Aging; Animals; Diet; DNA; Methionine; Pancreas; Rats; Serine; Staining and Labeling | 1969 |
[Pharmacodynamic effect of complex polyvitamin drugs on old animals].
Topics: Aging; Animals; Ascorbic Acid; Drug Combinations; Flavonoids; Methionine; Niacinamide; Rabbits; Rats; Regeneration; Vitamin A; Vitamin B Complex; Vitamin E; Vitamins; Wound Healing | 1974 |
Influences on the structural stability of collagen in relation to ageing.
Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; Formaldehyde; Methionine; Muscle Contraction; Penicillamine; Perchlorates; Rats; Sodium Chloride; Tail; Tendons | 1973 |
In vivo methylation and turnover of rat brain histones.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Half-Life; Histones; Lysine; Male; Methionine; Methylation; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; Regression Analysis; Time Factors; Tritium | 1974 |
Appearance of a kidney-specific ribosomal protein during mouse embryonic development.
Topics: Aging; Animals; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Female; Gestational Age; Kidney; Liver; Methionine; Mice; Organ Specificity; Pregnancy; Protein Biosynthesis; Ribosomes; Sulfur Radioisotopes; Tritium; Ultracentrifugation | 1974 |
Stimulation of ornithine decarboxylase activity by luteinizing hormone in immature and adult rat ovaries.
Topics: Aging; Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Gel; Cycloheximide; Dactinomycin; Estrus; Female; Hydrogen-Ion Concentration; Kinetics; Luteinizing Hormone; Methionine; Ornithine; Ovary; Pregnancy; Puromycin; Rats; RNA; Time Factors; Tritium; Uridine | 1973 |
Effect of antioxidants and nutrients on lipid peroxidation fluorescent products and aging parameters in the mouse.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Body Weight; Calcium; Cresols; Diet; Kidney Function Tests; Lipid Metabolism; Male; Methionine; Mice; Mice, Inbred Strains; Microsomes; Mortality; Muscles; Myocardium; Oxidation-Reduction; Physical Exertion; Pigments, Biological; Selenium; Spectrometry, Fluorescence; Testis; Vitamin E | 1973 |
Protein methylases during the development of rat brain.
Topics: Aging; Animals; Body Weight; Brain; Carbon Radioisotopes; Cell Nucleus; Cerebellum; Cytosol; Liver; Lysine; Medulla Oblongata; Mesencephalon; Methionine; Methyltransferases; Mice; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; S-Adenosylmethionine; Subcellular Fractions; Tritium | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
The subunit structure of alpha-crystallin. Isolation and characterization of the S-carboxymethylated acidic subunits from adult and embryonic origin.
Topics: Aging; Alkylation; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Cattle; Chromatography, Ion Exchange; Crystallins; Electrophoresis; Gels; Immunodiffusion; Lens, Crystalline; Methionine; Molecular Weight; Peptides; Rabbits; Serine; Sulfhydryl Compounds; Ultracentrifugation; Urea | 1969 |
Methylation of DNA in vivo by thymus, spleen, and liver of the rat.
Topics: Aging; Aminopterin; Animals; Animals, Newborn; Brucella abortus; Carbon Isotopes; Chromatography, Paper; DNA; Liver; Metabolism; Methionine; Methylation; Mitomycins; Nucleotides; Orotic Acid; Rats; Spleen; Thymus Gland; Time Factors; Tritium | 1970 |
Methylmalonate, formiminoglutamate and aminoimidazolecarboxamide excretion of vitamin B 12 -deficient germfree and conventional rats.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Creatinine; Deficiency Diseases; FIGLU Test; Germ-Free Life; Glutamates; Imidazoles; Intestines; Male; Malonates; Methionine; Rats; Stereoisomerism; Structure-Activity Relationship; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
Comparison of cytoplasmic glycerol-3-phosphate dehydrogenase from rat liver and muscle.
Topics: Acetates; Acrylamides; Aging; Amino Acids; Animals; Body Weight; Cellulose; Cytoplasm; Electrophoresis; Electrophoresis, Disc; Glutamates; Glutamine; Glycerolphosphate Dehydrogenase; Isoelectric Focusing; Isoenzymes; Liver; Methionine; Muscles; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Time Factors | 1971 |
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietary Proteins; Enzyme Induction; Enzyme Repression; Glucagon; Homocysteine; Hormones; Liver; Male; Methionine; Methyltransferases; Organ Specificity; Rats; Tetrahydrofolates; Ultracentrifugation | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Age-dependency of various protein methylases.
Topics: Aging; Amines; Amino Acids; Animals; Brain; Brain Chemistry; Liver; Male; Methionine; Methods; Methylamines; Methylation; Methyltransferases; Proteins; Rats; Testis | 1971 |
The influence of endotoxin administration on the nutritional requirements of mice.
Topics: Aging; Amino Acids; Animals; Body Weight; Dietary Proteins; Endotoxins; Escherichia coli; Glutens; Lysine; Methionine; Mice; Nutritional Physiological Phenomena; Threonine; Valine | 1965 |
75Se-selenomethionine turnover rate during growth and aging in rats.
Topics: Aging; Animals; Body Weight; Growth; Kinetics; Male; Methionine; Protein Biosynthesis; Rats; Selenium | 1970 |
[Age characteristics of the penetrability and renovation of amino acids (S 35-methionine) in the uveal tract and retina of the eye].
Topics: Aging; Animals; Methionine; Methods; Rabbits; Retina; Sulfur Isotopes; Uvea | 1970 |
Utilization of L-methionine sulfoxide by the rat.
Topics: Adaptation, Physiological; Aging; Amino Acids; Animals; Body Weight; Diet; Food; Hair; Hydrogen Peroxide; Lipid Metabolism; Liver; Male; Methionine; Nitrogen; Oxidation-Reduction; Rats; Sulfoxides; Water | 1970 |
Polyamines. (1) Enhanced s-adenosyl-L-methionine decarboxylase in rapid growth systems, and (2) the relationships between polyamine concentration and RNA accumulation.
Topics: Aging; Amines; Animals; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chick Embryo; Enzyme Induction; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Male; Methionine; Ornithine; Polyamines; Rats; RNA; S-Adenosylmethionine; Spermine; Time Factors; Tritium; Uridine | 1971 |
Differentiation of metabolism in muscles of different function during ontogenesis.
Topics: Aging; Animals; Animals, Newborn; Glycogen; Methionine; Muscle Denervation; Muscle Development; Muscle Proteins; Muscles; Neuromuscular Junction; Potassium; Rats; Sulfur Isotopes | 1968 |
Selenium and genetically dystrophic hamsters.
Topics: Aging; Animals; Biological Transport, Active; Cricetinae; Glucose; Intestinal Absorption; Intestine, Small; Kidney; Liver; Male; Methionine; Muscles; Muscular Dystrophies; Myocardium; Organ Size; Radioisotopes; Selenium | 1968 |
Rate of protein renewal in spinal motoneurons of adolescent and old rats.
Topics: Aging; Animals; Autoradiography; Histocytochemistry; Methionine; Microscopy, Interference; Motor Neurons; Nerve Tissue Proteins; Rats; Spinal Cord; Sulfur Isotopes | 1968 |
Autoradiography of intestinal absorption of sulphur-labeled methionine in senescence.
Topics: Aging; Animals; Autoradiography; Intestinal Absorption; Jejunum; Methionine; Rats; Sulfur Isotopes | 1968 |
Intestinal absorption and utilization of radiomethionine in old age.
Topics: Aging; Animals; Autoradiography; Female; Intestinal Absorption; Intestine, Small; Liver; Mathematics; Methionine; Models, Biological; Rats; Sulfur Isotopes | 1968 |
Protein synthesis by red and white muscle in vitro: effect of insulin and animal age.
Topics: Aging; Animals; Carbon Isotopes; In Vitro Techniques; Insulin; Male; Methionine; Muscles; Protein Biosynthesis; Rats | 1969 |
Phospholipid metabolism in the developing liver. I. The biosynthesis of choline glycerophosphatides by liver slices from fetal, newborn and adult rats.
Topics: Aging; Animals; Animals, Newborn; Carbon Isotopes; Choline; Chromatography, Thin Layer; Female; Fetus; Glycerophosphates; Liver; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus Isotopes; Pregnancy; Rats; Tritium | 1969 |
Choline metabolism in normal and choline-deficient rats of different ages.
Topics: Aging; Animals; Body Weight; Choline; Choline Deficiency; Fatty Liver; Hemorrhage; Kidney; Liver; Methionine; Rats; Vitamin B Deficiency | 1965 |
A study of total body protein turnover in rats of different ages.
Topics: Aging; Animals; Female; Methionine; Proteins; Radioisotopes; Rats; Selenium | 1965 |