methimazole and Retinal-Diseases

We present a case of a 40-years-old woman with an acute posterior multifocal placoid pigment epitheliopathy (APMPPE) associated with recent instauration hyperthyroidism symptoms. A Graves' disease was diagnosed and the patient was initially controlled with antithyroid drugs. The epitheliopathy evolution was relatively favourable without relapse. Two years later a thyroidectomy was performed.. We have not found in the literature any APMPPE case associated with Graves' disease. We only found an APMPPE case associated with a subacute thyroiditis. Little is known about the APMPPE causes, it could be that placoid epitheliopathy and Graves' disease had a common autoimmune origin. We can not forget that our finding could be only a matter of chance.

Topics: Acute Disease; Adult; Antithyroid Agents; Choroid; Combined Modality Therapy; Female; Fluorescein Angiography; Graves Disease; Hormone Replacement Therapy; Humans; Ischemia; Methimazole; Pigment Epithelium of Eye; Radiography; Retinal Diseases; Thyroidectomy; Thyroiditis, Subacute; Thyroxine