methimazole and Opportunistic-Infections

Both Graves disease and Guillain-Barre syndrome (GBS) are autoimmune disorders caused by impaired self-tolerance mechanisms and triggered by interactions between genetic and environmental factors. GBS in patients who suffer from other autoimmune diseases is rarely reported, and the development of postinfectious GBS in a patient with Graves disease has not been previously reported in the literature. Herein, we report a patient with Graves disease who developed postinfectious GBS during a course of methimazole-induced agranulocytosis.

Topics: Agranulocytosis; Antithyroid Agents; Female; Graves Disease; Guillain-Barre Syndrome; Humans; Immunoglobulins, Intravenous; Methimazole; Middle Aged; Opportunistic Infections; Thyroidectomy; Treatment Outcome