methimazole and Cecal-Diseases
methimazole has been researched along with Cecal-Diseases* in 2 studies
Other Studies
2 other study(ies) available for methimazole and Cecal-Diseases
Article | Year |
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Neutropenic colitis with cecal perforation during antithyroid therapy.
Neutropenic colitis, characterized by neutropenia plus cecal and ascending colon inflammation, is a rare complication of chemotherapy in hematological malignancies and, less commonly, of medication used to treat other diseases (e.g., hyperthyroidism). We report a case of neutropenic colitis with cecal perforation in a 44-year-old woman treated with methimazole for hyperthyroidism. The patient had received subtotal thyroidectomy for hyperthyroidism in 1984 and recurrent hyperthyroidism was found in 1993. She was then treated with methimazole for almost 3 months, when sustained fever, diarrhea, weakness, and progressive abdominal pain developed. Due to the findings of peritonitis and neutropenia, she underwent emergent laparotomy. During the operation, chronic ulceration of the cecum with perforation was found and resection of the ileocecal segment and ileostomy were performed. Three months later, closure of the ileostomy with anastomosis of the ileocolostomy was performed. Her condition was stable during 9 years' follow-up. In conclusion, neutropenic enterocolitis has a broad spectrum of clinical presentations that require alertness in patients with neutropenia. When detected late, it may lead to bowel perforation and even mortality. Topics: Adult; Antithyroid Agents; Cecal Diseases; Colitis; Female; Humans; Hyperthyroidism; Intestinal Perforation; Methimazole; Neutropenia | 2003 |
Typhlitis complicating methimazole-induced agranulocytosis.
Topics: Adolescent; Agranulocytosis; Cecal Diseases; Colonoscopy; Female; Humans; Inflammation; Methimazole | 1983 |