methenolone and Liver-Cirrhosis

Topics: Anabolic Agents; Animals; Carbon Tetrachloride Poisoning; Clinical Trials as Topic; Drug Evaluation; Humans; Liver; Liver Cirrhosis; Liver Regeneration; Male; Methenolone; Rats; Testosterone

15 patients with a histologically and/or peritoneoscopically proven cirrhosis of the liver were treated for four weeks with 200 mg metenolonenanthate (Depot-Primobolan) per week. Before and after the treatment the intravascular and extravascular pool and daily turnover of albumin were measured with 125J-albumin. All patients had a well "compensated" cirrhosis. The only significant difference between the values of the cirrhotic patients and those of a control group of patients was a reduction of the albumin turn-over. The anabolic steroid enlarged the turn-over, the effect was the more pronounced the more pronounced the more the turn over was diminished before the treatment.

Topics: Adult; Aged; Blood Vessels; Female; Humans; Liver Cirrhosis; Male; Methenolone; Middle Aged; Serum Albumin; Serum Albumin, Radio-Iodinated; Time Factors

Topics: Adult; Aged; Amino Acids; Ammonia; Brain Diseases; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Fasting; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methenolone; Middle Aged; Peptic Ulcer; Prednisolone; Syphilis; Tolbutamide; Tryptophan

Topics: Acid Phosphatase; Anabolic Agents; Chronic Disease; Electrophoresis; Humans; Liver Cirrhosis; Liver Function Tests; Methenolone; Sulfobromophthalein; Transaminases

Topics: Anabolic Agents; Animals; Carbon Tetrachloride; Collagen; Liver Cirrhosis; Methenolone; Osteoporosis; Rats; Sulfur Isotopes

Topics: Anatomy; Hepatitis; Hepatitis A; Humans; Liver Cirrhosis; Liver Diseases; Methenolone; Steroids