Page last updated: 2024-10-30

methenamine and Urinary Tract Infections

methenamine has been researched along with Urinary Tract Infections in 179 studies

Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.

Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.

Research Excerpts

ExcerptRelevanceReference
"Methenamine hippurate is a urinary antiseptic used as preventive treatment for recurrent urinary tract infections (UTIs) in some Scandinavian countries."9.51Methenamine hippurate to prevent recurrent urinary tract infections in older women: protocol for a randomised, placebo-controlled trial (ImpresU). ( Åhrén, C; Godycki-Cwirko, M; Groen, WG; Grude, N; Gunnarsson, R; Heltveit-Olsen, SR; Hertogh, CMPM; Hoye, S; Koning, HAM; Kowalczyk, A; Lindbaek, M; Platteel, TN; Snaebjörnsson Arnljots, E; Sundvall, PD; Verheij, TJM, 2022)
"The objective was to find an alternative treatment to a low-dose antibiotic for the prevention of recurrent urinary tract infections (UTI) and to evaluate the difference in rates of reinfection within 1 year when treated with methenamine hippurate for prophylaxis compared with trimethoprim."9.51Methenamine hippurate compared with trimethoprim for the prevention of recurrent urinary tract infections: a randomized clinical trial. ( Biener, A; Botros, C; Botros-Brey, S; Gafni-Kane, A; Goldberg, R; Iyer, S; Lozo, S; Sand, P; Sasso, K; Tomezsko, J; Warren, A, 2022)
"Twenty girls, aged 5-12 years, with recurrent urinary tract infections, were treated with methenamine hippurate, Hiprex, for a period of 12 months."9.04Long-term prophylaxis with methenamine hippurate in girls with recurrent urinary tract infections. ( Petersen, S, 1978)
"This study was designed to determine the effect of methenamine on the frequency of urinary tract infections (UTI) in hospitalized patients after spinal cord injury."7.68Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine. ( Banovac, K; Gonzalez, F; Rhamy, RK; Wade, N; Walsh, B, 1991)
"To study the effects of continous low doses of antibacterial agents after eradication of bacteriuria in patients with recurrent urinary tract infection, 31 patients with documented recurrent urinary tract infection were allocated alternately to treatment with either co-trimoxazole (400 mg of suphamethoxazole and 80 mg of trimethoprim each night) or methenamine hippurate (1 g each night)."7.65Controlled trial comparing co-trimoxazole and methenamine hippurate in the prevention of recurrent urinary tract infections. ( Friedman, A; Kalowski, S; Kincaid-Smith, P; Nanra, RS; Radford, N; Standish, H, 1975)
"62."6.65Secondary prevention of recurrent urinary tract infections. Comparison of the effect of placebo, methenamine hippurate, nitrofurantoin and trimethoprim alone. ( Hajba, A; Junnila, SY; Kaarsalo, E; Kasanen, A; Sundquist, H, 1982)
"Methenamine hippurate seems to enhance barrier function as evidenced by decreased urothelial permeability and increased urinary IgA levels, without worsening inflammation."5.72The Impact of Methenamine Hippurate Treatment on Urothelial Integrity and Bladder Inflammation in Aged Female Mice and Women With Urinary Tract Infections. ( Chu, CM; Ligon, MM; Lowder, JL; McDaniel, K; Mora, A; Mysorekar, IU; Sawhill, JL, 2022)
"To test and compare the efficacy of methenamine hippurate for prevention of recurrent urinary tract infections with the current standard prophylaxis of daily low dose antibiotics."5.51Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial. ( Abouhajar, A; Ali, A; Carnell, S; Chadwick, T; Currer, S; Eardley, I; Forbes, R; Guerrero, K; Harding, C; Homer, T; Hussain, Z; King, W; Lazarowicz, H; Lecouturier, J; Mossop, H; Pearce, I; Pickard, R; Thiruchelvam, N; Vale, L; Walton, K; Watson, G, 2022)
" Methenamine had few adverse side effects for patients."5.51Safety and efficacy of methenamine hippurate for the prevention of recurrent urinary tract infections in adult renal transplant recipients: A single center, retrospective study. ( Ho, B; Hollyer, I; Ison, MG; Varias, F, 2019)
"To determine whether Methenamine Hippurate (MH) or cranberry tablets prevent urinary tract infections (UTI) in people with neuropathic bladder following spinal cord injury (SCI)."5.12Spinal-injured neuropathic bladder antisepsis (SINBA) trial. ( Cameron, ID; Haran, MJ; Hunt, LM; Kotsiou, G; Lee, BB; Marial, O; Middleton, JW; Rutkowski, SB; Simpson, JM; Tudehope, M, 2007)
"Twenty girls, aged 5-12 years, with recurrent urinary tract infections, were treated with methenamine hippurate, Hiprex, for a period of 12 months."5.04Long-term prophylaxis with methenamine hippurate in girls with recurrent urinary tract infections. ( Petersen, S, 1978)
" Because urinary tract infections (UTIs) are common, particularly in an increasing elderly population, the 'forgotten' drug, methenamine, may become important as a preventive therapy for recurrent UTIs."4.90Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era. ( Cho, WC; Hammer, KD; Lo, TS; Zegarra, M, 2014)
" Nalidixic acid and oxolinic acid, in addition to effectiveness in treating uncomplicated acute lower urinary tract infections, may be effective in some patients with recurrent infections, but requires careful sensitivity monitoring of pathogens for the development of resistance."4.76Urinary tract antiseptics. ( Andriole, VT; Mayrer, AR, 1982)
"This study was designed to determine the effect of methenamine on the frequency of urinary tract infections (UTI) in hospitalized patients after spinal cord injury."3.68Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine. ( Banovac, K; Gonzalez, F; Rhamy, RK; Wade, N; Walsh, B, 1991)
"We studied prospectively 40 patients with recent spinal cord injuries to determine the effectiveness of the combination of oral methenamine and an intravesicular acidifying agent for prevention of urinary tract infection during intermittent catheterization."3.67Prevention of urinary tract infection during intermittent catheterization. ( Fishman, IJ; Halvorsen, RB; Krebs, M; Santos-Mendoza, N, 1984)
"To study the effects of continous low doses of antibacterial agents after eradication of bacteriuria in patients with recurrent urinary tract infection, 31 patients with documented recurrent urinary tract infection were allocated alternately to treatment with either co-trimoxazole (400 mg of suphamethoxazole and 80 mg of trimethoprim each night) or methenamine hippurate (1 g each night)."3.65Controlled trial comparing co-trimoxazole and methenamine hippurate in the prevention of recurrent urinary tract infections. ( Friedman, A; Kalowski, S; Kincaid-Smith, P; Nanra, RS; Radford, N; Standish, H, 1975)
"Treatment with trimethoprim reduced significantly the periurethral colonization of Escherichia coli."2.65Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine. ( Brumfitt, W; Cooper, J; Gargan, RA; Hamilton-Miller, JM; Smith, GW, 1983)
"62."2.65Secondary prevention of recurrent urinary tract infections. Comparison of the effect of placebo, methenamine hippurate, nitrofurantoin and trimethoprim alone. ( Hajba, A; Junnila, SY; Kaarsalo, E; Kasanen, A; Sundquist, H, 1982)
"Patients with spinal cord injuries are at increased risk of developing symptomatic urinary tract infections."2.52Australian Institute of Sport and the Australian Paralympic Committee position statement: urinary tract infection in spinal cord injured athletes. ( Compton, S; Cunningham, C; Hughes, D; Trease, L, 2015)
"The mechanism of action, spectrum of antimicrobial activity, pharmacokinetics, adverse effects, therapeutic use, and dosage of methenamine hippurate and methenamine mandelate are reviewed."2.36Drug therapy reviews: methenamine mandelate and methenamine hippurate. ( Alvarez, S; Gleckman, R; Joubert, DW; Matthews, SJ, 1979)
"New developments in treatment of urinary tract infections will be discussed."2.35New developments in the diagnosis and treatment of urinary tract infections. ( Kunn, CM, 1975)
"Methenamine hippurate seems to enhance barrier function as evidenced by decreased urothelial permeability and increased urinary IgA levels, without worsening inflammation."1.72The Impact of Methenamine Hippurate Treatment on Urothelial Integrity and Bladder Inflammation in Aged Female Mice and Women With Urinary Tract Infections. ( Chu, CM; Ligon, MM; Lowder, JL; McDaniel, K; Mora, A; Mysorekar, IU; Sawhill, JL, 2022)
" Methenamine had few adverse side effects for patients."1.51Safety and efficacy of methenamine hippurate for the prevention of recurrent urinary tract infections in adult renal transplant recipients: A single center, retrospective study. ( Ho, B; Hollyer, I; Ison, MG; Varias, F, 2019)
" Based on information on drug, dosage and indication, we assessed whether the use of antibiotics for the treatment of UTIs was in accordance with the National Guidelines for the Use of Antibiotics in Primary Care."1.46Antibiotic use and infections in nursing homes. ( Alberg, T; Bentele, H; Blix, HS; Eriksen, HM; Holen, Ø; Lindbæk, M, 2017)
"Methenamine was used by 48% of residents prescribed prophylaxis, vitamin C by 32%, and cranberry products by 10%."1.37Prevention of urinary tract infections in nursing homes: lack of evidence-based prescription? ( Bergman, J; Blix, HS; Schjøtt, J, 2011)
" No adverse reactions were recorded with the dosage used."1.28Long-term acidification of urine in patients treated for infected renal stones. ( Tiselius, HG; Wall, I, 1990)
"Recurrent urinary tract infections are known to occur among 5 per cent of all females."1.26The microbial flora of the urogenital tract in women with symptoms of recurrent urinary tract infection. The non-influence of methenaminehippurate treatment on the idigenous flora. ( Colleen, S; Luttropp, W; Mårdh, PA; Ripa, T, 1978)

Research

Studies (179)

TimeframeStudies, this research(%)All Research%
pre-1990143 (79.89)18.7374
1990's2 (1.12)18.2507
2000's5 (2.79)29.6817
2010's14 (7.82)24.3611
2020's15 (8.38)2.80

Authors

AuthorsStudies
Sweiss, H1
Bhayana, S1
Hall, R1
Nelson, J1
Kincaide, E1
Harding, C5
Mossop, H2
Homer, T1
Chadwick, T2
King, W1
Carnell, S2
Lecouturier, J3
Abouhajar, A2
Vale, L1
Watson, G1
Forbes, R2
Currer, S1
Pickard, R2
Eardley, I2
Pearce, I2
Thiruchelvam, N2
Guerrero, K1
Walton, K2
Hussain, Z1
Lazarowicz, H1
Ali, A2
Tam, TY1
Aldrich, ER1
Crisp, CC1
Yook, E1
Yeung, J1
Pauls, RN1
Sawhill, JL1
Mora, A1
McDaniel, K1
Ligon, MM1
Lowder, JL1
Mysorekar, IU1
Chu, CM1
Heltveit-Olsen, SR1
Sundvall, PD1
Gunnarsson, R1
Snaebjörnsson Arnljots, E1
Kowalczyk, A1
Godycki-Cwirko, M1
Platteel, TN1
Koning, HAM1
Groen, WG1
Åhrén, C1
Grude, N1
Verheij, TJM1
Hertogh, CMPM1
Lindbaek, M2
Hoye, S1
Rui, L1
Gjelstad, S1
Saul, H1
Deeney, B1
Cassidy, S1
Kwint, J1
Stair, SL1
Palmer, CJ1
Lee, UJ1
Churchill, K1
Gu, C1
Ackerman, AL1
Kale, S1
Somani, BK1
Quintero Cardona, O1
Hemmige, VS1
Puius, YA1
Bakhit, M1
Krzyzaniak, N1
Hilder, J1
Clark, J1
Scott, AM1
Mar, CD1
Botros, C1
Lozo, S1
Iyer, S1
Warren, A1
Goldberg, R1
Tomezsko, J1
Sasso, K1
Sand, P1
Gafni-Kane, A1
Biener, A1
Botros-Brey, S1
Abdelrahman, A1
Davis, C1
Rantell, A1
Barclay, J1
Veeratterapillay, R1
Lie, MLS1
Sihra, N1
Goodman, A1
Zakri, R1
Sahai, A1
Malde, S1
Brennand, C1
Brown, H1
Wilkinson, J1
Hollyer, I1
Varias, F1
Ho, B1
Ison, MG1
Lo, TS1
Hammer, KD1
Zegarra, M1
Cho, WC1
Jahromi, MS1
Mure, A1
Gomez, CS1
Haugen, W1
Spigset, O1
Compton, S1
Trease, L1
Cunningham, C1
Hughes, D1
Alberg, T1
Holen, Ø1
Blix, HS2
Lindbæk, M1
Bentele, H1
Eriksen, HM1
CARROLL, G1
ALLEN, HN1
Bergman, J1
Schjøtt, J1
Rummukainen, ML1
Kärki, T1
Kanerva, M1
Haapasaari, M1
Ollgren, J1
Lyytikäinen, O1
Lee, BS1
Bhuta, T3
Simpson, JM3
Craig, JC2
GOLDIN, M1
HOFFMAN, A1
KERLEY, L1
HEADLEE, CP1
WILDE, W1
BRAZEL, E1
BRAUN, H1
NEUMANN, H1
LEGAULT, JP1
BOURQUE, JP1
JOYAL, J1
GARVEY, FK2
MURRAY, HL2
HOLLAND, NH1
WEST, CD1
BLOCH, K1
ZANGWILL, DP1
PORTER, PJ1
KAITZ, AL1
COTRAN, RS1
BODEL, PT1
KASS, EH2
WILLIAMS, TW1
ABU-NASSAR, H1
YOW, EM1
LEBLANC, AL2
MCGANITY, WJ2
PLATTNER, HC1
SCHERER, J1
WENZL, JE1
GREENE, LF1
HARRIS, LE1
ZINSSER, HH2
HUSEBYE, KO1
BANWELL, A1
ULLMAN, A1
SENECA, H3
MORSE, JO1
ISHIZU, S1
FURUKAWA, M1
MACHIDA, T1
HASEGAWA, S1
YAMAMOTO, K1
BAKER, HA1
SIDOROWICZ, A1
Schiøtz, HA1
Tanbo, TG1
Lee, BB2
Haran, MJ1
Hunt, LM1
Marial, O1
Rutkowski, SB1
Middleton, JW1
Kotsiou, G1
Tudehope, M1
Cameron, ID1
Isik, SR1
Karakaya, G1
Erkin, G1
Kalyoncu, AF1
OBERHOLTZER, A1
Peer, P2
Bors, E1
Smellie, JM1
Kostiala, AA1
Nyrén, P2
Runeberg, L2
Olsen, JH1
Friis-Møller, A1
Jensen, SK1
Korner, B2
Hvidt, V1
Brumfitt, W2
Hamilton-Miller, JM2
Gargan, RA1
Cooper, J2
Smith, GW1
Kevorkian, CG1
Merritt, JL1
Ilstrup, DM1
Ladehoff, P1
Jacobsen, JC1
Olsen, H1
Pedersen, GT1
Sørensen, T1
Pelliniemi, TT1
Junnila, SY2
Kasanen, A5
Sundquist, H2
Elo, J2
Anttila, M1
Kangas, L1
Seppänen, J2
Sulkava, T1
Vaalasti, T1
Korhonen, H1
Räisänen, S2
Ylitalo, P2
Krebs, M1
Halvorsen, RB1
Fishman, IJ1
Santos-Mendoza, N1
Kaarsalo, E2
Hajba, A1
Simon, J1
Fuss, M1
Yourassowski, E1
Nahata, MC1
Cummins, BA1
McLeod, DC1
Weichers, DO1
Liang, DS1
Ballou, J1
Schönebeck, J1
Almgård, LE2
Boman, J1
Warren, JW1
Muncie, HL1
Bergquist, EJ1
Hoopes, JM1
Mayrer, AR1
Andriole, VT1
Popov, N1
Kostiala, AI1
Renkonen, OV1
Roine, R1
Stover, SL2
Fleming, WC1
Lee, B1
Craig, J1
Simpson, J1
Pearman, JW1
Peterson, GJ1
Nash, JB1
Norberg, B3
Norberg, A3
Parkhede, U3
Gippert, H3
Brocklehurst, JC1
Brocklehurst, S1
Akerman, M1
Udjus, ED1
Edman, T1
Sokol, S1
Jacobson, CB1
Derrick, FC1
Pedersen, FB1
Wesolowski, S1
Wencel, J1
Czaplicki, M1
Borkowski, A1
Petersen, S1
Gleckman, R1
Alvarez, S1
Joubert, DW1
Matthews, SJ1
Ekman, R1
Sperling, KB1
Senoh, K1
Iwatsubo, E1
Momose, S1
Colleen, S1
Luttropp, W1
Mårdh, PA1
Ripa, T1
Sarna, S1
Ahava, K1
Lepo, A1
Dimberg, L1
Sander, S2
Jakobsen, A1
Klein, D1
Puchegger, R1
Murray, CP1
Feeney, J1
Kivinen, S1
Tuimala, R1
Vainrub, B1
Musher, DM1
Keswani, RK1
Chugh, TD1
Hooda, RS1
Beniwal, JS1
Parvio, S1
Norrman, K1
Wibell, L1
Kunn, CM1
Sher, N1
Freeman, RB1
Smith, WM1
Richardson, JA1
Hennelly, PJ1
Thurm, RH1
Urner, C1
Vaillancourt, JA1
Griep, RJ1
Bromer, L1
Stamey, TA1
Chrapowicki, T2
Krzyzanowska-Rogozińska, T2
Kurowska, D2
Bergan, T1
Sander, J1
Kalowski, S2
Nanra, RS2
Friedman, A1
Radford, N1
Standish, H1
Kincaid-Smith, P2
Nowak, S1
Planeta-Malecka, I1
Bodalski, J1
Narebska, E1
Kozlowski, J1
Kostenko, D1
Lystad, A1
Banovac, K1
Wade, N1
Gonzalez, F1
Walsh, B1
Rhamy, RK1
Wall, I1
Tiselius, HG1
Tyreman, NO1
Andersson, PO1
Kroon, L1
Orstam, S1
Jeantet, A1
Thea, A1
Ferrando, U1
Gaido, M1
Rotunno, M1
Martini, PF1
Vercellone, A1
Knoff, T1
Macfarlane, DE1
Toponen, A1
Greenblatt, DJ1
Luck, VR1
Genster, HG1
Madsen, PO1
Scetbon, V1
Peycelon-de la Selle, MF1
Gow, JG1
Lang, GR1
Levin, S1
Cox, CE1
Jelińska, S1
Gietko, G1
Harris, RE1
Gilstrap, LC1
Hiltunen, R1
Soini, V2
Sonnenschein, H2
Bugnon, A2
Sakellaridès, E2
Schelling, JL2
Bonifas, V2
Gillenwater, JY1
Sengupta, SR1
Bansal, MP1
Deshpande, PK1
Sharma, KD1
Bengtsson, U1
Orsten, PA1
Harding, GK1
Ronald, AR1
Mustakallio, E1
Koskinen, EH1
Budhraja, SN2
Rangiah, T1
Smile, SR1
Chidambaram, M1
Sharma, KB2
Wallerström, BG1
Saxena, H1
Pratap, VK1
Agnihotri, VS1
Ericsson, H1
von Garrelts, B1
Miller, JM1
Nepomuceno, CS1
Timmerman, RJ1
Schroer, JA1
Finland, M1
Desautels, RE1
Mitsuya, H1
Kondo, A1
Feins, NR1
Schlesinger, RM1
O'Connor, J1
Younnes, RP1
Lampe, WT1
Miller, H1
Phillips, E1
Muralidharan, S1
Santa ana, E1
Joos, HA1
Mackay, EV1
Macafee, CA1
Anderson, C1
Joseph, JI1
Joshi, W1
Joshi, AM1
Shuman, FI1
Goldberg, RI1
Bhujwala, RA1
Gibson, GR1
Sele, V1
Frandsen, VA1
Braverman, LE1
Reinstein, H1
Loayza, H1
Pomfret, D1
Gerstein, AR1
Okun, R1
Gonick, HC1
Wilner, HI1
Kleeman, CR1
Maxwell, MH1
Bohensky, FB1
Kawada, Y1
Nishimura, Y1
Nishiura, T1
Mehrotra, GC1
Jain, K1
Green, GS1
Johnson, RH1
Shively, JA1
Casselman, J1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Methenamine Hippurate With Cranberry Capsules Versus Cranberry Capsules Alone for UTI Prevention in a Short-term Indwelling Foley Catheter Population After Urogynecological Surgery: A Double-Blinded Randomized Controlled Trial[NCT03818321]Phase 2185 participants (Actual)Interventional2019-06-17Completed
The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing Due to New Episodes of Urinary Tract Infections (UTI) in Elderly Women With Recurrent UTI - a Triple- Blinded, Randomized Placebo-controlled Phase IV Study[NCT04077580]Phase 4400 participants (Anticipated)Interventional2019-11-01Enrolling by invitation
Probiotic and Effects on Multi-Drug Resistant Urinary Tract Infection[NCT03644966]25 participants (Actual)Interventional2018-07-05Completed
Clinical Trial of Nettle and Cranberry Capsules for Prevention of Urinary Tract Infection[NCT05880602]60 participants (Anticipated)Interventional2023-07-05Recruiting
The Efficacy and Cost-effectiveness of a 24-hour Course of metheNamine Hippurate for Preventing Post-Operative Urinary Tract Infection[NCT02358993]201 participants (Actual)Interventional2014-12-31Completed
Reducing Postoperative Catheterization After Urogynecology Surgery: A Randomized Trial[NCT03009968]150 participants (Actual)Interventional2017-03-17Completed
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery[NCT03048682]60 participants (Anticipated)Interventional2017-01-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Urinary Track Infection (UTI)

Incidence of UTIs will be diagnosed at one week post-op visit. (NCT03818321)
Timeframe: From surgery to one week post-op visit, approximately 1 week post surgery

InterventionParticipants (Count of Participants)
Methenamine Hippurate With Cranberry62
Placebo With Cranberry71

Antibiotic Resistance of Culture-positive Symptomatic UTI

All patients who submit urine cultures that are positive will have sensitivities performed as per standard care. The prevalence of bacterial species and sensitivities will be collected (NCT02358993)
Timeframe: 3 weeks post-operative

InterventionParticipants (Count of Participants)
Methenamine0
Ciprofloxacin0

Number of Participants With Culture-positive Symptomatic UTI

All patients will be encouraged to submit urine cultures prior to treatment, but this is not always possible. Amongst patients who undergo urine culture as part of standard of care for UTI, the rate of positive cultures will be identified. (NCT02358993)
Timeframe: 3 weeks post-operative

InterventionParticipants (Count of Participants)
Methenamine5
Ciprofloxacin4

Rate of UTI Consistent With NHSN Criteria

We plan to analyze the prevalence of UTI in this population that meet the definitions of symptomatic UTI and catheter-associated UTI according to the National Healthcare Safety Network criteria. (NCT02358993)
Timeframe: 3 weeks post-operative

InterventionParticipants (Count of Participants)
Methenamine10
Ciprofloxacin6

Treatment of Clinically Suspected UTI - Per Protocol

This is defined as any symptomatic UTI requiring treatment with antibiotics as determined by the development of 2 or more of the following symptoms, in the absence of vaginal symptoms: urinary frequency; urinary urgency; dysuria; fever over 38oC/100.4oF; suprapubic, flank, or back pain; and/or chills. (NCT02358993)
Timeframe: 3 weeks post-operative

InterventionParticipants (Count of Participants)
Methenamine12
Ciprofloxacin12

Treatment of Clinically Suspected UTI - Using Intent to Treat Analysis

This is defined as any symptomatic UTI requiring treatment with antibiotics as determined by the development of 2 or more of the following symptoms, in the absence of vaginal symptoms: urinary frequency; urinary urgency; dysuria; fever over 38oC/100.4oF; suprapubic, flank, or back pain; and/or chills. (NCT02358993)
Timeframe: 3 weeks post-operative

InterventionParticipants (Count of Participants)
Methenamine13
Ciprofloxacin12

Reviews

18 reviews available for methenamine and Urinary Tract Infections

ArticleYear
Evidence-based review of nonantibiotic urinary tract infection prevention strategies for women: a patient-centered approach.
    Current opinion in urology, 2023, 05-01, Volume: 33, Issue:3

    Topics: Complementary Therapies; Estrogens; Female; Humans; Methenamine; Patient-Centered Care; Recurrence;

2023
The resurgence of methenamine hippurate in the prevention of recurrent UTIs in women- a systematic review.
    Current opinion in urology, 2023, 11-01, Volume: 33, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Female; Hippurates; Humans; Methenamine; Urinary Tract Infections

2023
Use of methenamine hippurate to prevent urinary tract infections in community adult women: a systematic review and meta-analysis.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2021, Volume: 71, Issue:708

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Hippurates; Humans; Methenamine; Pharmaceutical Pr

2021
Nonantibiotic prevention and management of recurrent urinary tract infection.
    Nature reviews. Urology, 2018, Volume: 15, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Estrogens; Female; Hippurates; Humans; Male; Mannose; Methe

2018
Methenamine: a forgotten drug for preventing recurrent urinary tract infection in a multidrug resistance era.
    Expert review of anti-infective therapy, 2014, Volume: 12, Issue:5

    Topics: Anti-Infective Agents, Urinary; Drug Administration Schedule; Drug Dosage Calculations; Drug Resista

2014
UTIs in patients with neurogenic bladder.
    Current urology reports, 2014, Volume: 15, Issue:9

    Topics: Administration, Intravesical; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antibiotic Prop

2014
Australian Institute of Sport and the Australian Paralympic Committee position statement: urinary tract infection in spinal cord injured athletes.
    British journal of sports medicine, 2015, Volume: 49, Issue:19

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Australia; Consensus;

2015
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2012
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2012
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2012
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2012
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2007, Oct-17, Issue:4

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2007
Sequelae and management of urinary infection in the patient requiring chronic catheterization.
    The Journal of urology, 1981, Volume: 125, Issue:1

    Topics: Anti-Bacterial Agents; Catheters, Indwelling; Humans; Methenamine; Pyelonephritis; Therapeutic Irrig

1981
Urinary tract antiseptics.
    The Medical clinics of North America, 1982, Volume: 66, Issue:1

    Topics: Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Humans; Methenamine; Nalidixic Acid; Nitrofur

1982
Methenamine hippurate for preventing urinary tract infections.
    The Cochrane database of systematic reviews, 2002, Issue:1

    Topics: Anti-Infective Agents, Urinary; Hippurates; Humans; Methenamine; Randomized Controlled Trials as Top

2002
Drug therapy reviews: methenamine mandelate and methenamine hippurate.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:11

    Topics: Bacteria; Drug Interactions; Hippurates; Humans; Kidney Diseases; Kinetics; Mandelic Acids; Methenam

1979
New developments in the diagnosis and treatment of urinary tract infections.
    The Journal of urology, 1975, Volume: 113, Issue:5

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Carbenicillin; Female; Humans; Hydroxamic

1975
Prevention and treatment of catheter-associated urinary tract infections.
    The Journal of infection, 1985, Volume: 10, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Infections; Bacteriuria; Catheters, Indwelling; Cross Infection; Hu

1985
Diagnosis and treatment of urinary tract infections.
    The Medical clinics of North America, 1971, Volume: 55, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteriuria; Cephalosporins; Chloramphenicol;

1971
Symposium on renal lithiasis. Urinary tract infection and renal lithiasis.
    The Urologic clinics of North America, 1974, Volume: 1, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalosporins; Chloramphenicol; Humans;

1974
Ureteral reflux in pediatric patients.
    American journal of surgery, 1971, Volume: 122, Issue:3

    Topics: Anti-Bacterial Agents; Ascorbic Acid; Child; Child, Preschool; Endoscopy; Female; Humans; Infant; Ki

1971

Trials

38 trials available for methenamine and Urinary Tract Infections

ArticleYear
Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial.
    BMJ (Clinical research ed.), 2022, 03-09, Volume: 376

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Female; Hippurates; Humans; Methen

2022
Methenamine Hippurate With Cranberry Capsules Versus Cranberry Alone for Urinary Tract Infection Prevention in a Short-Term Indwelling Foley Catheter Population After Urogynecologic Surgery: A Double-Blinded Randomized Controlled Trial.
    Female pelvic medicine & reconstructive surgery, 2022, 03-01, Volume: 28, Issue:3

    Topics: Capsules; Catheters; Female; Hippurates; Humans; Male; Methenamine; Urinary Tract Infections; Vaccin

2022
Methenamine hippurate to prevent recurrent urinary tract infections in older women: protocol for a randomised, placebo-controlled trial (ImpresU).
    BMJ open, 2022, 11-01, Volume: 12, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Clinical Trials, Phase IV as Topic; Escherichia coli; Female; Humans; M

2022
Methenamine is as effective as antibiotics at preventing urinary tract infections.
    BMJ (Clinical research ed.), 2023, 01-17, Volume: 380

    Topics: Anti-Bacterial Agents; Female; Humans; Methenamine; Urinary Tract Infections

2023
Methenamine hippurate compared with trimethoprim for the prevention of recurrent urinary tract infections: a randomized clinical trial.
    International urogynecology journal, 2022, Volume: 33, Issue:3

    Topics: Female; Hippurates; Humans; Methenamine; Trimethoprim; Urinary Tract Infections

2022
Should I stay or should I go? A qualitative study exploring participation in a urology clinical trial.
    International urogynecology journal, 2019, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; C

2019
ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): study protocol for a multicentre, pragmatic, patient-randomised, non-inferiority trial.
    Trials, 2018, Nov-09, Volume: 19, Issue:1

    Topics: Adult; Aged; Antibiotic Prophylaxis; Bias; Computer Security; Female; Hippurates; Humans; Methenamin

2018
Spinal-injured neuropathic bladder antisepsis (SINBA) trial.
    Spinal cord, 2007, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Double-Blind Method; Fem

2007
Effect of nitrofurantoin and methenamine hippurate prophylaxis on bacteria and yeasts in the urine of patients with an indwelling catheter.
    The Journal of hospital infection, 1982, Volume: 3, Issue:4

    Topics: Aged; Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Clinical Trials as Topic; Female; Hippu

1982
Cefotaxime for prevention of infectious complications in bacteriuric men undergoing transurethral prostatic resection. A controlled comparison with methenamine.
    Scandinavian journal of urology and nephrology, 1983, Volume: 17, Issue:3

    Topics: Aged; Cefotaxime; Clinical Trials as Topic; Hippurates; Humans; Male; Methenamine; Middle Aged; Post

1983
Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine.
    The Journal of urology, 1983, Volume: 130, Issue:6

    Topics: Administration, Topical; Adult; Clinical Trials as Topic; Drug Eruptions; Drug Resistance, Microbial

1983
Methenamine mandelate with acidification: an effective urinary antiseptic in patients with neurogenic bladder.
    Mayo Clinic proceedings, 1984, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Ammonium Chloride; Anti-Infective Agents, Urinary; Clinical Trials as Topic

1984
[The preventive effect of methenamine hippurate (Haiprex) on urinary infections after short-term catheterization. A clinical study].
    Ugeskrift for laeger, 1984, May-07, Volume: 146, Issue:19

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Catheters, Indwelling; Female; Hippurates; Humans; Male

1984
Secondary prevention of urinary tract infections. The role of trimethoprim alone.
    Annals of clinical research, 1983, Volume: 15, Issue:Suppl 36

    Topics: Adult; Anti-Infective Agents; Child; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Met

1983
Combination of trimethoprim and methenamine hippurate in the treatment of acute urinary tract infections.
    Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Double-Blind Method; Drug Co

1983
Secondary prevention of recurrent urinary tract infections. Comparison of the effect of placebo, methenamine hippurate, nitrofurantoin and trimethoprim alone.
    Scandinavian journal of infectious diseases, 1982, Volume: 14, Issue:4

    Topics: Clinical Trials as Topic; Hippurates; Humans; Methenamine; Nitrofurantoin; Placebos; Recurrence; Tri

1982
Antibiotics to patients with urinary infections in connection with transurethral prostatectomy.
    Scandinavian journal of infectious diseases, 1980, Volume: 12, Issue:2

    Topics: Aged; Cefazolin; Cephalexin; Clinical Trials as Topic; Humans; Male; Methenamine; Postoperative Comp

1980
Prevention of recurrent urinary infections in women: a comparative trial between nitrofurantoin and methenamine hippurate.
    The Journal of urology, 1981, Volume: 126, Issue:1

    Topics: Adult; Anti-Infective Agents, Urinary; Clinical Trials as Topic; Female; Hippurates; Humans; Methena

1981
Prophylactic methenamine hippurate or nitrofurantoin in patients with an indwelling urinary catheter.
    Annals of clinical research, 1981, Volume: 13, Issue:1

    Topics: Aged; Antibody-Coated Bacteria Test, Urinary; Bacterial Infections; Catheters, Indwelling; Female; H

1981
Effect of short-term high-dose treatment with methenamine hippurate on urinary infection in geriatric patients with an indwelling catheter. IV. Clinical evaluation.
    European journal of clinical pharmacology, 1979, Jun-12, Volume: 15, Issue:5

    Topics: Aged; Catheters, Indwelling; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans;

1979
[Urinary tract infection after prostate surgery. A controlled, clinical-bacteriological comparison between methenamine hippurate (Haiprex) and phenylsalicylate methenamine preparations].
    Ugeskrift for laeger, 1977, Jun-06, Volume: 139, Issue:23

    Topics: Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Humans; Male; Methenamine; Postoperati

1977
Long-term prophylaxis with methenamine hippurate in girls with recurrent urinary tract infections.
    Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:5

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Hippurates; Humans; Meth

1978
[Preventive Hiprex in urinary tract operations].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Jan-30, Volume: 96, Issue:3

    Topics: Aged; Clinical Trials as Topic; Hippurates; Humans; Male; Methenamine; Middle Aged; Postoperative Co

1976
[Methenamine hippurate in urinary tract infections].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Jul-31, Volume: 52, Issue:21

    Topics: Chronic Disease; Clinical Trials as Topic; Hippurates; Humans; Methenamine; Pyelonephritis; Urinary

1976
A comparison of hexamine hippurate and sulphamethizolein patients with indwelling catheters following pelvic-floor surgery.
    Irish medical journal, 1977, Feb-28, Volume: 69, Issue:4

    Topics: Catheters, Indwelling; Hippurates; Humans; Methenamine; Pelvis; Postoperative Care; Sulfamethizole;

1977
Long-term therapy for chronic bacteriuria in men. U.S. Public Health Service cooperative study.
    Annals of internal medicine, 1975, Volume: 83, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Chronic Disease; Clinical Trials as Topic;

1975
[Treatment of acute and chronic urinary tract infections in children with an urinary chemotherapeutic agent].
    Zeitschrift fur Allgemeinmedizin, 1975, Sep-30, Volume: 51, Issue:27

    Topics: Acute Disease; Adolescent; Age Factors; Child; Child, Preschool; Chronic Disease; Clinical Trials as

1975
Urinary tract infection after vaginal surgery. Effect of prophylactic treatment with methenamine hippurate.
    Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:7

    Topics: Aged; Anti-Infective Agents, Urinary; Catheters, Indwelling; Clinical Trials as Topic; Female; Hippu

1986
[Methenamine hippurate. Short-term catheterization in gynecologic surgery. A double-blind comparison of Hiprex and placebo].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1985, Mar-10, Volume: 105, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Clinical Trials as Topic; Doub

1985
[Value of mandelamine in the prolonged treatment of urinary infections caused by escherichia coli].
    Therapeutique (La Semaine des hopitaux), 1973, Volume: 49, Issue:4

    Topics: Clinical Trials as Topic; Escherichia coli Infections; Humans; Long-Term Care; Methenamine; Urinary

1973
A comparative trial of hexamine hippurate and hexamine mandelate in prevention of recurrent infection of the urinary tract.
    The Practitioner, 1974, Volume: 213, Issue:1273

    Topics: Albuminuria; Back Pain; Clinical Trials as Topic; Depression; Diarrhea; Digestion; Drug Hypersensiti

1974
Comparison of long-term, low-dosage nitrofurantoin, methenamine hippurate, trimethoprim and trimethoprim-sulphamethoxazole on the control of recurrent urinary tract infection.
    Annals of clinical research, 1974, Volume: 6, Issue:5

    Topics: Aged; Drug Tolerance; Female; Hippurates; Humans; In Vitro Techniques; Male; Methenamine; Middle Age

1974
[Antibiotic sensitivity and immediate clinical response in urinary tract infections].
    Schweizerische medizinische Wochenschrift, 1972, Oct-07, Volume: 102, Issue:40

    Topics: Ampicillin; Analysis of Variance; Anti-Bacterial Agents; Bacteria; Bacteriuria; Clinical Trials as T

1972
Co-trimoxazole in urinary tract infection.
    The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:2

    Topics: Acute Kidney Injury; Adult; Anti-Infective Agents; Bacteriuria; Clinical Trials as Topic; Drug Combi

1973
[Clinical testing of methenamine hippurate (Hiprex) in the treatment of urinary tract infections].
    Lakartidningen, 1973, Dec-05, Volume: 70, Issue:49

    Topics: Adolescent; Adult; Aged; Bacteriuria; Clinical Trials as Topic; Drug Evaluation; Female; Gastrointes

1973
A controlled study of antimicrobial prophylaxis of recurrent urinary infection in women.
    The New England journal of medicine, 1974, Sep-19, Volume: 291, Issue:12

    Topics: Adolescent; Adult; Aged; Ascorbic Acid; Bacteria; Bacteriological Techniques; Child; Child, Preschoo

1974
Methenamine hippurate (Hiprex).
    The Medical letter on drugs and therapeutics, 1968, Jul-26, Volume: 10, Issue:15

    Topics: Acute Disease; Bacteria; Chronic Disease; Clinical Trials as Topic; Hippurates; Humans; Methenamine;

1968
Evaluation of a combined therapy in the treatment and prophylaxis of urinary infections.
    Connecticut medicine, 1965, Volume: 29, Issue:10

    Topics: Adult; Aged; Benzoates; Clinical Trials as Topic; Female; Humans; Lithium; Male; Methenamine; Middle

1965

Other Studies

123 other studies available for methenamine and Urinary Tract Infections

ArticleYear
Methenamine for Recurrent Urinary Tract Infections in Solid Organ Transplantation.
    Progress in transplantation (Aliso Viejo, Calif.), 2022, Volume: 32, Issue:1

    Topics: Bacteriuria; Female; Hippurates; Humans; Kidney Transplantation; Male; Methenamine; Urinary Tract In

2022
The Impact of Methenamine Hippurate Treatment on Urothelial Integrity and Bladder Inflammation in Aged Female Mice and Women With Urinary Tract Infections.
    Female pelvic medicine & reconstructive surgery, 2022, 06-01, Volume: 28, Issue:6

    Topics: Animals; Cystitis; Dextrans; Estrogens; Female; Fluoresceins; Hippurates; Humans; Immunoglobulin A;

2022
Preventive effect of methenamine in women with recurrent urinary tract infections - a case-control study.
    Scandinavian journal of primary health care, 2022, Volume: 40, Issue:3

    Topics: Anti-Bacterial Agents; Case-Control Studies; Female; General Practice; Humans; Methenamine; Urinary

2022
The management of recurrent urinary tract infections within a nurse-led urology team.
    British journal of nursing (Mark Allen Publishing), 2023, May-11, Volume: 32, Issue:9

    Topics: Female; Hippurates; Humans; Male; Methenamine; Nurse's Role; Urinary Tract Infections; Urology

2023
An oldie but a goodie: Methenamine as a nonantibiotic solution to the prevention of recurrent urinary tract infections.
    PLoS pathogens, 2023, Volume: 19, Issue:6

    Topics: Humans; Methenamine; Recurrence; Urinary Tract Infections

2023
Methenamine hippurate may have particular benefit in preventing recurrent urinary tract infections in diabetic renal transplant recipients.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:2

    Topics: Diabetes Mellitus; Hippurates; Humans; Kidney Transplantation; Methenamine; Urinary Tract Infections

2020
Commentary on "Methenamine hippurate compared with trimethoprim for the prevention of recurrent urinary tract infections: a randomized clinical trial".
    International urogynecology journal, 2022, Volume: 33, Issue:3

    Topics: Hippurates; Humans; Methenamine; Trimethoprim; Urinary Tract Infections

2022
Lower urinary tract infections in women.
    British journal of nursing (Mark Allen Publishing), 2017, May-11, Volume: 26, Issue:9

    Topics: Age Factors; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Asymptomatic Infections; Atrophi

2017
Non-antibiotic options for recurrent urinary tract infections in women.
    BMJ (Clinical research ed.), 2017, 11-23, Volume: 359

    Topics: Antibiotic Prophylaxis; Drugs, Chinese Herbal; Evidence-Based Medicine; Female; Hippurates; Humans;

2017
Non-antibiotic options for recurrent urinary tract infections in women.
    BMJ (Clinical research ed.), 2017, 11-23, Volume: 359

    Topics: Antibiotic Prophylaxis; Drugs, Chinese Herbal; Evidence-Based Medicine; Female; Hippurates; Humans;

2017
Non-antibiotic options for recurrent urinary tract infections in women.
    BMJ (Clinical research ed.), 2017, 11-23, Volume: 359

    Topics: Antibiotic Prophylaxis; Drugs, Chinese Herbal; Evidence-Based Medicine; Female; Hippurates; Humans;

2017
Non-antibiotic options for recurrent urinary tract infections in women.
    BMJ (Clinical research ed.), 2017, 11-23, Volume: 359

    Topics: Antibiotic Prophylaxis; Drugs, Chinese Herbal; Evidence-Based Medicine; Female; Hippurates; Humans;

2017
Safety and efficacy of methenamine hippurate for the prevention of recurrent urinary tract infections in adult renal transplant recipients: A single center, retrospective study.
    Transplant infectious disease : an official journal of the Transplantation Society, 2019, Volume: 21, Issue:3

    Topics: Adult; Anti-Infective Agents, Urinary; Bacteria; Escherichia coli; Female; Hippurates; Humans; Kidne

2019
[How to prevent recurrent urinary tract infections after menopause?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2015, Jan-13, Volume: 135, Issue:1

    Topics: Aged; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Estrogens;

2015
Antibiotic use and infections in nursing homes.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2017, Volume: 137, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Bacteriuria; Cros

2017
The treatment of urinary infections with mandelamine (methenamine mandelate); a clinical study of 200 cases.
    The Journal of urology, 1946, Volume: 55

    Topics: Humans; Mandelic Acids; Methenamine; Urinary Tract Infections

1946
Prevention of urinary tract infections in nursing homes: lack of evidence-based prescription?
    BMC geriatrics, 2011, Nov-01, Volume: 11

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascorbic Acid; Evidence-Based Medicine; Female; Home

2011
Antimicrobial prescribing in nursing homes in Finland: results of three point prevalence surveys.
    Infection, 2013, Volume: 41, Issue:2

    Topics: Aged, 80 and over; Amdinocillin Pivoxil; Anti-Bacterial Agents; Antibiotic Prophylaxis; Confidence I

2013
Determination of sensitivity of bacteria from urinary tract infections to methenamine mandelate by the disc method.
    Antibiotic medicine & clinical therapy (New York, NY), 1955, Volume: 1, Issue:8

    Topics: Bacteria; Bacterial Infections; Humans; Mandelic Acids; Methenamine; Microbial Sensitivity Tests; Ur

1955
Bacterial resistance studies involving several drugs useful in the treatment of urinary tract disease.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1956, Volume: 45, Issue:2 Part 1

    Topics: Bacterial Infections; Humans; Mandelic Acids; Methenamine; Sulfonamides; Urinary Tract Infections

1956
[A new urinary tract disinfectant (mandelamine)].
    Medizinische Monatsschrift, 1955, Volume: 9, Issue:11

    Topics: Disinfectants; Humans; Mandelic Acids; Methenamine; Sterilization; Urinary Tract Infections

1955
[Treatment of urinary tract infections in women with buccosperin].
    Therapie der Gegenwart, 1956, Volume: 95, Issue:3

    Topics: Female; Humans; Methenamine; Urinary Tract Infections

1956
[Optimal therapy in urinary tract infections].
    Hippokrates, 1957, May-15, Volume: 28, Issue:9

    Topics: Humans; Methenamine; Urinary Tract Infections

1957
[Alteration of urinary pH by a polyvalent urinary antiseptic].
    Die Medizinische, 1957, Dec-28, Volume: 2, Issue:52

    Topics: Anti-Infective Agents, Urinary; Bile Ducts; Humans; Liver Diseases; Methenamine; Urinary Tract Infec

1957
[A new acidifying urinary antiseptic, antispasmodic & sedative].
    L'union medicale du Canada, 1958, Volume: 87, Issue:3

    Topics: Anti-Infective Agents, Local; Anti-Infective Agents, Urinary; Belladonna Alkaloids; Homeostasis; Hyp

1958
[Use of methenamine mandelate in 100 non-selected cases of urinary tract infection].
    L'union medicale du Canada, 1959, Volume: 88, Issue:5

    Topics: Humans; Mandelic Acids; Methenamine; Urinary Tract Infections

1959
A clinical report on the use of combined mandelamine and thiosulfil in resistant urinarv tract infections.
    North Carolina medical journal, 1961, Volume: 22

    Topics: Communicable Diseases; Mandelic Acids; Methenamine; North Carolina; Sulfamethizole; Sulfanilamide; S

1961
A clinical and laboratory study of combined mendelamine and thiosulfil in resistant urinary tract infections.
    North Carolina medical journal, 1960, Volume: 21

    Topics: Humans; Methenamine; North Carolina; Research; Sulfamethizole; Thiosulfates; Urinary Tract Infection

1960
Prevention of recurrent urinary tract infections in girls.
    American journal of diseases of children (1960), 1963, Volume: 105

    Topics: Biomedical Research; Female; Humans; Methenamine; Preventive Medicine; Urinary Tract Infections

1963
[Nil nocere; Precautions in the therapeutic use of hexamethylenetetramine preparations in combination with sulfonamides].
    Munchener medizinische Wochenschrift (1950), 1962, Nov-23, Volume: 104

    Topics: Anuria; Bile Ducts; Methenamine; Sulfanilamide; Sulfanilamides; Sulfonamides; Urinary Tract Infectio

1962
Antibacterial organic acids in chronic urinary tract infection. Use in long-term management.
    Archives of internal medicine, 1962, Volume: 110

    Topics: Anti-Bacterial Agents; Disease Management; Hippurates; Methenamine; Methionine; Pyelonephritis; Urin

1962
METHENAMINE MANDELATE-SULFAMETHIZOLE COMBINATION; EVALUATION IN MANAGEMENT OF URINARY TRACT INFECTIONS.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Enterobacter; Escherichia coli; Humans; Infections; Klebsiella; Mandelic Acids; Methenamine; Proteus

1964
BACTERIURIA IN PREGNANCY. PRELIMINARY REPORT.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Bacteria; Bacteriuria; Communicable Diseases; Female; Humans; Infant; Infant, Premature; Kidney Papi

1964
[CHEMOTHERAPY OF URINARY INFECTIONS].
    Schweizerische medizinische Wochenschrift, 1964, Feb-08, Volume: 94

    Topics: Anti-Bacterial Agents; Blood Chemical Analysis; Chloramphenicol; Escherichia coli Infections; Humans

1964
EOSINOPHILIC CYSTITIS.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Biopsy; Child; Congenital Abnormalities; Cystitis; Eosinophilia; Escherichia coli Infections; Humans

1964
NEWER ANTIBACTERIAL DRUGS IN UROLOGICAL INFECTIONS.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Ammonium Chloride; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Chlor

1964
THE IMPACT OF BACTERIURIA IN PREGNANCY; A SURVEY OF 1300 PREGNANT PATIENTS.
    Texas reports on biology and medicine, 1964, Volume: 22

    Topics: Amniotic Fluid; Bacteriuria; Black People; Drug Therapy; Enterobacter; Escherichia coli Infections;

1964
JAUNDICE WITH PERSISTING PERICHOLANGIOLITIC INFLAMMATION IN A PATIENT TREATED WITH CHLOROTHIAZIDE. REPORT OF A CASE.
    The American journal of digestive diseases, 1964, Volume: 9

    Topics: Biopsy; Cerebral Hemorrhage; Chemical and Drug Induced Liver Injury; Chlorothiazide; Coronary Diseas

1964
HENOCH-SCHOENLEIN PURPURA; COMPLICATED BY DEEP VEIN THROMBOSIS, SUBARACHNOID HAEMORRHAGE AND PARAPLEGIA.
    Nursing times, 1964, Jun-26, Volume: 60

    Topics: Anemia; Anemia, Hypochromic; Chlorpromazine; Heparin; Humans; IgA Vasculitis; Iron; Methenamine; Nan

1964
METHENAMINE MANDELATE (MANDELAMINE) IN URINARY TRACT INFECTIONS.
    Medical times, 1964, Volume: 92

    Topics: Biomedical Research; Drug Therapy; Humans; Hydrogen-Ion Concentration; Mandelic Acids; Methenamine;

1964
CURRENT THERAPY OF INFECTIONS OF THE RENAL EXCRETORY SYSTEM.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Amphotericin B; Anti-Bacterial Agents; Anti-Infective Agents; Azo Compounds; Bacitracin; Chlormerodr

1964
NEWER USES OF OLD DRUGS IN THE TREATMENT OF URINARY TRACT INFECTIONS.
    Journal of the Medical Association of Georgia, 1965, Volume: 54

    Topics: Ascorbic Acid; Drug Therapy; Humans; Methenamine; Methionine; Urinary Tract Infections

1965
[USE OF A COMBINED DRUG OF SULFAMETHYLTHIADIAZOLE AND METHENAMINE MANDELATE FOR TREATMENT OF URINARY TRACT INFECTION].
    Hinyokika kiyo. Acta urologica Japonica, 1964, Volume: 10

    Topics: Drug Therapy; Humans; Mandelic Acids; Methenamine; Sulfathiazoles; Urinary Tract Infections

1964
Therapy of urinary tract infections based on in vitro studies with a combination of sulfamethylthiadiazole and methenamine mandelate.
    Clinical medicine (Northfield, Ill.), 1963, Volume: 70

    Topics: Humans; In Vitro Techniques; Mandelic Acids; Methenamine; Research; Sulfathiazoles; Urinary Tract In

1963
Postoperative voiding, bacteriuria and urinary tract infection with Foley catheterization after gynecological surgery.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:4

    Topics: Anti-Infective Agents, Urinary; Bacteria; Clinical Trials as Topic; Female; Gynecologic Surgical Pro

2006
Postoperative voiding, bacteriuria and urinary tract infection with Foley catheterization after gynecological surgery.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:4

    Topics: Anti-Infective Agents, Urinary; Bacteria; Clinical Trials as Topic; Female; Gynecologic Surgical Pro

2006
Postoperative voiding, bacteriuria and urinary tract infection with Foley catheterization after gynecological surgery.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:4

    Topics: Anti-Infective Agents, Urinary; Bacteria; Clinical Trials as Topic; Female; Gynecologic Surgical Pro

2006
Postoperative voiding, bacteriuria and urinary tract infection with Foley catheterization after gynecological surgery.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:4

    Topics: Anti-Infective Agents, Urinary; Bacteria; Clinical Trials as Topic; Female; Gynecologic Surgical Pro

2006
Multidrug-induced erythema multiforme.
    Journal of investigational allergology & clinical immunology, 2007, Volume: 17, Issue:3

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Ceftriaxone; Ci

2007
Association of hexamethylenetetramine vitamin C in urinary infections.
    Urologia, 1948, Oct-20, Volume: 15, Issue:5

    Topics: Anti-Infective Agents, Urinary; Ascorbic Acid; Humans; Methenamine; Urinary Tract; Urinary Tract Inf

1948
Chemotherapy of chronic urinary tract infections with methenamine hippurate.
    The Journal of urology, 1967, Volume: 97, Issue:6

    Topics: Hippurates; Humans; Methenamine; Urinary Tract Infections

1967
Intermittent catheterization in paraplegic patients.
    Urologia internationalis, 1967, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Ascorbic Acid; Bethanechol Compounds; Humans; Male; Methenamine; Middle Age

1967
Effect of pH of the urine on antimicrobial therapy of urinary tract infections.
    The Medical letter on drugs and therapeutics, 1967, Jun-16, Volume: 9, Issue:12

    Topics: Anti-Infective Agents, Urinary; Chloramphenicol; Humans; Hydrogen-Ion Concentration; Kanamycin; Mand

1967
[Preventive antibiotic therapy of recurring urinary tract infections in children].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:6

    Topics: Child; Child, Preschool; Female; Humans; Infant; Male; Methenamine; Nalidixic Acid; Nitrofurantoin;

1981
[Trimethoprim does not cause folic acid deficiency].
    Duodecim; laaketieteellinen aikakauskirja, 1984, Volume: 100, Issue:23-24

    Topics: Blood Cell Count; Erythrocytes; Female; Folic Acid Deficiency; Humans; Male; Methenamine; Nitrofuran

1984
Prevention of urinary tract infection during intermittent catheterization.
    The Journal of urology, 1984, Volume: 131, Issue:1

    Topics: Bacteriuria; Citrates; Humans; Mandelic Acids; Methenamine; Prospective Studies; Spinal Cord Injurie

1984
Urinary infection in renal stone patients.
    European urology, 1980, Volume: 6, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Escherichia coli; Female; Humans; Klebsiella; Male; Methenamine;

1980
Urinary formaldehyde concentration after methenamine therapy in patients on intermittent catheterization.
    The Journal of family practice, 1983, Volume: 16, Issue:2

    Topics: Adult; Catheters, Indwelling; Female; Formaldehyde; Humans; Hydrogen-Ion Concentration; Male; Methen

1983
Long term catheter care with infected urine.
    Rhode Island medical journal, 1981, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Mandelic Acids; Methenamine; Middle Aged; Nitrofurant

1981
[Molecular biology aspects of the antimicrobial effect of synthetic chemotherapeutic agents].
    Zeitschrift fur arztliche Fortbildung, 1982, Aug-01, Volume: 76, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biotransformation; Delayed-Action Pr

1982
Recurrent bacteriuria in complete spinal cord injury patients on external condom drainage.
    Archives of physical medicine and rehabilitation, 1980, Volume: 61, Issue:4

    Topics: Anti-Infective Agents, Urinary; Aspirin; Bacteriuria; Evaluation Studies as Topic; Hippurates; Human

1980
The antimicrobial activity of urine of paraplegic patients receiving methenamine mandelate.
    Investigative urology, 1978, Volume: 16, Issue:2

    Topics: Adult; Bacteriuria; Drug Evaluation; Enterococcus faecalis; Escherichia coli; Formaldehyde; Humans;

1978
The management of indwelling catheters.
    British journal of urology, 1978, Volume: 50, Issue:2

    Topics: Anti-Bacterial Agents; Catheters, Indwelling; Evaluation Studies as Topic; Humans; Hydrogen-Ion Conc

1978
The effect of short-term high-dose treatment with methenamine hippurate of urinary infection in geriatric patients with indwelling catheters. I. The preparation and morphology of a quantified urine sediment.
    Upsala journal of medical sciences, 1979, Volume: 84, Issue:1

    Topics: Aged; Catheters, Indwelling; Drug Evaluation; Female; Glutaral; Hippurates; Humans; Male; Methenamin

1979
[Methenaminenippurate (Hiprex), an alternatice in treatment of chronic urinary tract infections].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Feb-28, Volume: 95, Issue:6

    Topics: Aged; Ascorbic Acid; Chronic Disease; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Male;

1975
Use of methenamine hippurate in male infertility.
    Urology, 1975, Volume: 6, Issue:1

    Topics: Cell Count; Humans; Hydrogen-Ion Concentration; Infertility, Male; Leukocyte Count; Male; Methenamin

1975
Antibacterial prophylaxis in patients after prostatectomy.
    International urology and nephrology, 1977, Volume: 9, Issue:3

    Topics: Aged; Bacterial Infections; Chloramphenicol; Enterobacteriaceae Infections; Escherichia coli Infecti

1977
The effect of short-term high-dose treatment with methenamine hippurate of urinary infection in geriatric patients with indwelling catheters. II. Evaluation by means of a quantified urine sediment.
    Upsala journal of medical sciences, 1979, Volume: 84, Issue:1

    Topics: Aged; Bacteriuria; Catheters, Indwelling; Drug Evaluation; Hippurates; Humans; Leukocyte Count; Meth

1979
An approach to the management of resistant urinary infections.
    Kidney international, 1979, Volume: 16, Issue:2

    Topics: Adult; Anti-Infective Agents, Urinary; Bacterial Infections; Drug Resistance, Microbial; Female; Hip

1979
Intermittent catheterization to obtain catheter-free bladder function in spinal cord injury.
    Archives of physical medicine and rehabilitation, 1978, Volume: 59, Issue:1

    Topics: Ascorbic Acid; Female; Follow-Up Studies; Humans; Methenamine; Nitrofurantoin; Spinal Cord Injuries;

1978
Followup study after conservative and surgical treatment of vesicoureteral reflux.
    The Journal of urology, 1978, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Blood Sedimentation; Child; Child, Preschool; Dilatation, Pathologic; Female; Fol

1978
The microbial flora of the urogenital tract in women with symptoms of recurrent urinary tract infection. The non-influence of methenaminehippurate treatment on the idigenous flora.
    Investigative urology, 1978, Volume: 15, Issue:5

    Topics: Adult; Bacteroides; Enterobacteriaceae; Female; Humans; Methenamine; Pyuria; Recurrence; Urinary Tra

1978
Methenamine hippurate in urinary tract infections in children: prophylaxis, treatment and side effects.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:4

    Topics: Age Factors; Child; Humans; Methenamine; Nitrofurantoin; Recurrence; Sulfisoxazole; Urinary Tract In

1978
[Treatment with methenamine hippurate in patients with indwelling urinary catheters].
    Lakartidningen, 1979, Feb-07, Volume: 76, Issue:6

    Topics: Aged; Catheters, Indwelling; Hippurates; Humans; Methenamine; Urinary Catheterization; Urinary Tract

1979
[Decreased maternal urinary estriol due to methenamine hippurate administration during pregnancy].
    Duodecim; laaketieteellinen aikakauskirja, 1977, Volume: 93, Issue:9

    Topics: Estriol; Female; Hippurates; Humans; Methenamine; Pregnancy; Pregnancy Complications, Infectious; Ur

1977
Lack of effect of methenamine in suppression of, or prophylaxis against, chronic urinary infection.
    Antimicrobial agents and chemotherapy, 1977, Volume: 12, Issue:5

    Topics: Ascorbic Acid; Catheters, Indwelling; Chronic Disease; Drug Therapy, Combination; Humans; Male; Meth

1977
Prevention of recurrent urinary tract infection with methenamine mandelate.
    The Indian journal of medical research, 1976, Volume: 64, Issue:8

    Topics: Humans; Methenamine; Recurrence; Urinary Tract Infections

1976
Methenamine hippurate ('Hiprex') in the treatment of chronic urinary tract infections: a trial in a geriatric hospital.
    The Journal of international medical research, 1976, Volume: 4, Issue:2

    Topics: Aged; Chronic Disease; Drug Evaluation; Female; Humans; Methenamine; Recurrence; Urinary Tract Infec

1976
Treatment with methenamine hippurate in the patient with a catheter.
    The Journal of international medical research, 1976, Volume: 4, Issue:2

    Topics: Aged; Bacteriuria; Catheters, Indwelling; Chronic Disease; Female; Humans; Methenamine; Urinary Cath

1976
Prophylactic chemotherapy with low-dosage trimethoprim-sulfamethoxazole following acute urinary tract infections in children.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Ampicillin; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Esche

1975
Editorial: A clinical classification of urinary tract infections based upon origin.
    Southern medical journal, 1975, Volume: 68, Issue:8

    Topics: Bacteriuria; Chronic Disease; Escherichia coli Infections; Female; Humans; Male; Methenamine; Nitrof

1975
[Urinary tract antiseptics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Feb-28, Volume: 95, Issue:6

    Topics: Diarrhea; Dyspepsia; Methenamine; Urinary Tract Infections

1975
[Mandelamine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, May-26, Volume: 30, Issue:21

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Methenamine; Urin

1975
Controlled trial comparing co-trimoxazole and methenamine hippurate in the prevention of recurrent urinary tract infections.
    The Medical journal of Australia, 1975, May-10, Volume: 1, Issue:19

    Topics: Adult; Aged; Bacteriuria; Drug Combinations; Female; Follow-Up Studies; Hemagglutinins; Hippurates;

1975
[Treatment of urinary tract infections in children].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1975, Aug-15, Volume: 28, Issue:16

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Male; Met

1975
[Catheterization and urinary tract infections].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Dec-10, Volume: 95, Issue:34-36

    Topics: Chlorhexidine; Humans; Methenamine; Urinary Catheterization; Urinary Tract Infections

1975
Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine.
    The Journal of the American Paraplegia Society, 1991, Volume: 14, Issue:2

    Topics: Bacteriuria; Bed Rest; Female; Humans; Male; Methenamine; Spinal Cord Injuries; Urinary Tract Infect

1991
Long-term acidification of urine in patients treated for infected renal stones.
    Urologia internationalis, 1990, Volume: 45, Issue:6

    Topics: Adult; Ammonium Chloride; Anti-Infective Agents, Urinary; Ascorbic Acid; Female; Hippurates; Humans;

1990
Infectious nephrolithiasis: results of treatment with methenamine mandelate.
    Contributions to nephrology, 1987, Volume: 58

    Topics: Adult; Anti-Infective Agents, Urinary; Calcium Oxalate; Female; Humans; Hydrogen-Ion Concentration;

1987
Trimethoprim and methenamine hippurate. A new theoretical combination for the treatment of urinary tract infections.
    Scandinavian journal of infectious diseases, 1985, Volume: 17, Issue:2

    Topics: Adult; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Escherichia coli Infec

1985
Urinary-tract infection and low-dose nitrofurantoin.
    Lancet (London, England), 1971, Dec-18, Volume: 2, Issue:7738

    Topics: Ascorbic Acid; Costs and Cost Analysis; Humans; Methenamine; Nitrofurantoin; Urinary Tract Infection

1971
Oral contraceptives.
    The Medical journal of Australia, 1966, Nov-05, Volume: 2, Issue:19

    Topics: Adult; Amobarbital; Chlormadinone Acetate; Contraceptives, Oral; Female; Humans; Mestranol; Methenam

1966
Continuous chemotherapy in the prevention of recurrent bacteriuria.
    Lancet (London, England), 1969, Feb-01, Volume: 1, Issue:7588

    Topics: Anti-Infective Agents, Urinary; Bacteriuria; Child; Child, Preschool; Female; Follow-Up Studies; Hum

1969
Urinary tract infections following transurethral prostatectomy: with special reference to the use of antimicrobials.
    The Journal of urology, 1970, Volume: 104, Issue:1

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Ceph

1970
[Prevention of urinary tract infections].
    Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methenamine; Middle Aged; Nitrofurantoin; Quinolines;

1974
Prevention of recurrent pyelonephritis during pregnancy.
    Obstetrics and gynecology, 1974, Volume: 44, Issue:5

    Topics: Adult; Ampicillin; Anti-Infective Agents, Urinary; Bacteriuria; Cephalothin; Female; Humans; Methena

1974
Recurring urinary tract infection. An overview.
    New York state journal of medicine, 1973, Apr-01, Volume: 73, Issue:7

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Female; Humans; Infant; Male; Methenamine; Recurrenc

1973
[Comparative study of 5 anti-infective drugs in urinary infections in hospital patients].
    Helvetica medica acta, 1972, Volume: 36, Issue:2

    Topics: Ampicillin; Anti-Infective Agents, Urinary; Bacteriuria; Doxycycline; Escherichia coli; Humans; Meth

1972
Recurrent urinary infection.
    Postgraduate medicine, 1973, Volume: 53, Issue:2

    Topics: Anti-Bacterial Agents; Bacteriological Techniques; Bacteriuria; Child; Cystitis; Female; Humans; Kid

1973
Bacteriology of urinary tract infections and the effectiveness of antimicrobials against the urinary pathogens.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Bacteriuria; Escherichia coli; Huma

1972
Methenamine hippurate in the treatment of urinary tract infections.
    Annals of clinical research, 1974, Volume: 6, Issue:5

    Topics: Acute Disease; Adult; Creatinine; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Inf

1974
An assessment of the value of prolonged use of methanamine mandelate in the treatment of chronic urinary tract infections.
    Indian journal of medical sciences, 1972, Volume: 26, Issue:6

    Topics: Chronic Disease; Female; Humans; Male; Methenamine; Recurrence; Time Factors; Urinary Tract Infectio

1972
[Methamine hippurate--an old antiseptic in a new formula].
    Lakartidningen, 1972, Dec-06, Volume: 69, Issue:50

    Topics: Acute Disease; Administration, Oral; Adult; Chronic Disease; Cystitis; Drug Combinations; Female; Hi

1972
In vitro comparison of ampicillin and other antimocrobial agents in non-tubercular urinary tract infections.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:5

    Topics: Ampicillin; Bacteria; Chloramphenicol; Humans; Methenamine; Microbial Sensitivity Tests; Nitrofurant

1972
[Prevention of infections in instrumental diagnosis of urethra].
    Lakartidningen, 1972, Dec-20, Volume: 69, Issue:52

    Topics: Hippurates; Humans; Male; Methenamine; Premedication; Time Factors; Urethra; Urinary Catheterization

1972
Intermittent catheterization in patients previously on indwelling catheter drainage.
    Archives of physical medicine and rehabilitation, 1973, Volume: 54, Issue:1

    Topics: Anti-Bacterial Agents; Bacteriuria; Follow-Up Studies; Home Nursing; Humans; Male; Methenamine; Meth

1973
[Spinal cord compression].
    Lakartidningen, 1973, Apr-25, Volume: 70, Issue:17

    Topics: Angiography; Animals; Ascorbic Acid; Blood Vessels; Cats; Female; Humans; Intervertebral Disc; Male;

1973
Lipoid pneumonia caused by methenamine mandelate suspension.
    JAMA, 1973, Sep-17, Volume: 225, Issue:12

    Topics: Aged; Female; Humans; Male; Methenamine; Oils; Pneumonia, Lipid; Sputum; Suspensions; Urinary Tract

1973
Editorial: Combinations of antimicrobial drugs: trimethoprim-sulfamethoxazole.
    The New England journal of medicine, 1974, Sep-19, Volume: 291, Issue:12

    Topics: Adult; American Medical Association; Ascorbic Acid; Attitude of Health Personnel; Bacterial Infectio

1974
Managing the urinary catheter.
    Geriatrics, 1974, Volume: 29, Issue:9

    Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Benzalkonium Compounds; Female

1974
[Problems of chronic urinary tract infection: clinical experience with hippramine].
    Hinyokika kiyo. Acta urologica Japonica, 1968, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Escherichia coli; Female; Humans; Hydrogen-Ion Concentration; Male; Methena

1968
Prolonged treatment of urinary tract infections: changing concepts of therapy.
    The Journal of urology, 1968, Volume: 100, Issue:4

    Topics: Anti-Infective Agents, Urinary; Bacteriuria; Chronic Disease; Female; Humans; Long-Term Care; Mandel

1968
Antibacterial correlates of urine drug levels of hexamethylenetetramine and formaldehyde.
    Investigative urology, 1970, Volume: 8, Issue:1

    Topics: Adult; Culture Media; Enterobacter; Escherichia coli; Formaldehyde; Hippurates; Humans; Hydrogen-Ion

1970
Clinical evaluation of gentamicin in Pseudomonas pyocyaneus infection of the urinary tract.
    Indian journal of medical sciences, 1971, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Gentamicins; Humans; Injections, Intramuscular; Long-Term Care; Methenamine; Midd

1971
Adverse effects of drugs commonly used in the treatment of urinary tract infection. A report from the Australian Drug Evaluation Committee.
    The Medical journal of Australia, 1972, Feb-26, Volume: 1, Issue:9

    Topics: Ampicillin; Anti-Infective Agents, Urinary; Australia; Chloramphenicol; Drug Hypersensitivity; Human

1972
A new look at steroid-resistant childhood nephrosis. The role of infection.
    Clinical pediatrics, 1968, Volume: 7, Issue:11

    Topics: Ampicillin; Ascorbic Acid; Child; Child, Preschool; Female; Humans; Male; Methenamine; Nephrosis; Ne

1968
Depression of urinary oestrogen values during methenamine mandelate administration.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1967, Volume: 7, Issue:2

    Topics: Adult; Estrogens; Female; Humans; Methenamine; Pregnancy; Pregnancy Complications, Infectious; Pregn

1967
Hypersensitivity to methenamine mandelate.
    The Journal of the Medical Society of New Jersey, 1971, Volume: 68, Issue:12

    Topics: Aged; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Male; Methenamine; Urinary Tract I

1971
Susceptibility of gram-negative bacilli isolated from urinary tract to methenamine mandelate [mandelamine (R)] and other antimicrobial agents: in vitro study.
    The Indian journal of medical research, 1969, Volume: 57, Issue:10

    Topics: Anti-Infective Agents, Urinary; Enterobacteriaceae; Methenamine; Microbial Sensitivity Tests; Urinar

1969
A clinical appraisal of methenamine hippurate in urinary tract infections.
    The Medical journal of Australia, 1970, Jan-24, Volume: 1, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Cystitis; Female; Hippurates; Humans; Male;

1970
Drug-interference with oestriol estimations during pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 1967, Volume: 46

    Topics: Anti-Infective Agents, Urinary; Estriol; Female; Glucuronidase; Methenamine; Pregnancy; Pregnancy Co

1967
Formaldehyde-forming drugs and urinary 17-hydroxycorticosteroids.
    Clinical chemistry, 1968, Volume: 14, Issue:4

    Topics: 17-Hydroxycorticosteroids; Colorimetry; Formaldehyde; Humans; Mandelic Acids; Methenamine; Phenylhyd

1968
The prolonged use of methenamine hippurate in the treatment of chronic urinary tract infection.
    The Journal of urology, 1968, Volume: 100, Issue:6

    Topics: Adult; Aged; Chronic Disease; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Male; Methenam

1968
Clinical pharmacology and antibacterial action of methenamine and its salts (mandelate, hippurate and sulfosalicylate).
    Medical times, 1969, Volume: 97, Issue:2

    Topics: Bacteria; Hippurates; Humans; Male; Mandelic Acids; Methenamine; Salicylates; Urinary Tract Infectio

1969
Suppression of bacteriuria by methenamine mandelate in aged hospital patients with chronic disease.
    Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:4

    Topics: Age Factors; Aged; Bacteriuria; Chronic Disease; Humans; Methenamine; Urinary Tract Infections

1969
[Laboratory and clinical studies on hippramine].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1969, Volume: 60, Issue:1

    Topics: Adult; Aged; Bacteria; Female; Formaldehyde; Hippurates; Humans; Hydrogen-Ion Concentration; Male; M

1969
Sensitivity of bacteria from urinary tract infections to hexamine mandelate and some common antibiotics.
    Journal of the Indian Medical Association, 1969, Apr-16, Volume: 52, Issue:8

    Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Humans; Mandelic Acids; Methenamine; Ur

1969
Mimeae: opportunistic pathogens.A review of infections in a cancer hospital.
    JAMA, 1965, Dec-06, Volume: 194, Issue:10

    Topics: Acinetobacter; Anti-Bacterial Agents; Humans; In Vitro Techniques; Infections; Methenamine; Phlebiti

1965
[Hexamethylene-tetramine hippurate in the treatment of urinary infections].
    Acta urologica Belgica, 1966, Volume: 34, Issue:3

    Topics: Animals; Anti-Infective Agents, Urinary; Dogs; Female; Hippurates; Humans; Male; Methenamine; Urinar

1966