methenamine has been researched along with Spinal Cord Injuries in 15 studies
Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to determine the effect of methenamine on the frequency of urinary tract infections (UTI) in hospitalized patients after spinal cord injury." | 7.68 | Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine. ( Banovac, K; Gonzalez, F; Rhamy, RK; Wade, N; Walsh, B, 1991) |
| "To determine whether Methenamine Hippurate (MH) or cranberry tablets prevent urinary tract infections (UTI) in people with neuropathic bladder following spinal cord injury (SCI)." | 5.12 | Spinal-injured neuropathic bladder antisepsis (SINBA) trial. ( Cameron, ID; Haran, MJ; Hunt, LM; Kotsiou, G; Lee, BB; Marial, O; Middleton, JW; Rutkowski, SB; Simpson, JM; Tudehope, M, 2007) |
| "We conducted 202 trials in 161 male hospital patients to determine if prophylactic administration of ascorbic acid or antibacterials (trimethoprim-sulfamethoxazole, nalidixic acid, methenamine hippurate or nitrofurantoin macrocrystals) would prevent bacteriuria infections in spinal cord injury patients who had had at least 1 bout of bacteriuria." | 5.05 | Prophylactic antibacterial therapy for preventing urinary tract infections in spinal cord injury patients. ( Kuhlemeier, KV; Lloyd, LK; Stover, SL, 1985) |
| "This study was designed to determine the effect of methenamine on the frequency of urinary tract infections (UTI) in hospitalized patients after spinal cord injury." | 3.68 | Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine. ( Banovac, K; Gonzalez, F; Rhamy, RK; Wade, N; Walsh, B, 1991) |
| "We studied prospectively 40 patients with recent spinal cord injuries to determine the effectiveness of the combination of oral methenamine and an intravesicular acidifying agent for prevention of urinary tract infection during intermittent catheterization." | 3.67 | Prevention of urinary tract infection during intermittent catheterization. ( Fishman, IJ; Halvorsen, RB; Krebs, M; Santos-Mendoza, N, 1984) |
| "To achieve effective suppression of bacteriuria in spinal cord injured (SCI) patients, methenamine mandelate and methenamine hippurate are commonly given with ascorbic acid." | 3.67 | Formaldehyde generation from methenamine salts in spinal cord injury. ( Devenport, JK; Dukes, GE; Sonsalla, PK; Swenson, JR, 1984) |
| "Patients with spinal cord injuries are at increased risk of developing symptomatic urinary tract infections." | 2.52 | Australian Institute of Sport and the Australian Paralympic Committee position statement: urinary tract infection in spinal cord injured athletes. ( Compton, S; Cunningham, C; Hughes, D; Trease, L, 2015) |
| " These results suggest that the long-term use of antimicrobial suppressants can help reduce rates of urinary tract infection in bladder-retrained patients and in patients emptying by intermittent self-catheterization." | 1.26 | Bacteriuria during follow-up in patients with spinal cord injury: II Efficacy of antimicrobial suppressants. ( Erickson, RP; Merritt, JL; Opitz, JL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jahromi, MS | 1 |
| Mure, A | 1 |
| Gomez, CS | 1 |
| Compton, S | 1 |
| Trease, L | 1 |
| Cunningham, C | 1 |
| Hughes, D | 1 |
| Lee, BB | 1 |
| Haran, MJ | 1 |
| Hunt, LM | 1 |
| Simpson, JM | 1 |
| Marial, O | 1 |
| Rutkowski, SB | 1 |
| Middleton, JW | 1 |
| Kotsiou, G | 1 |
| Tudehope, M | 1 |
| Cameron, ID | 1 |
| Bors, E | 1 |
| Krebs, M | 1 |
| Halvorsen, RB | 1 |
| Fishman, IJ | 1 |
| Santos-Mendoza, N | 1 |
| Devenport, JK | 1 |
| Swenson, JR | 1 |
| Dukes, GE | 1 |
| Sonsalla, PK | 1 |
| Lamid, S | 1 |
| Merritt, JL | 1 |
| Erickson, RP | 1 |
| Opitz, JL | 1 |
| Stover, SL | 3 |
| Fleming, WC | 1 |
| Sperling, KB | 1 |
| Banovac, K | 1 |
| Wade, N | 1 |
| Gonzalez, F | 1 |
| Walsh, B | 1 |
| Rhamy, RK | 1 |
| Arego, DE | 1 |
| Koch, SJ | 1 |
| Kuhlemeier, KV | 1 |
| Lloyd, LK | 1 |
| Miller, JM | 1 |
| Nepomuceno, CS | 1 |
2 reviews available for methenamine and Spinal Cord Injuries
| Article | Year |
|---|---|
UTIs in patients with neurogenic bladder.
Topics: Administration, Intravesical; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antibiotic Prop | 2014 |
Australian Institute of Sport and the Australian Paralympic Committee position statement: urinary tract infection in spinal cord injured athletes.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Australia; Consensus; | 2015 |
2 trials available for methenamine and Spinal Cord Injuries
| Article | Year |
|---|---|
Spinal-injured neuropathic bladder antisepsis (SINBA) trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Double-Blind Method; Fem | 2007 |
Prophylactic antibacterial therapy for preventing urinary tract infections in spinal cord injury patients.
Topics: Anti-Infective Agents, Urinary; Ascorbic Acid; Bacteriuria; Clinical Trials as Topic; Drug Combinati | 1985 |
11 other studies available for methenamine and Spinal Cord Injuries
| Article | Year |
|---|---|
Intermittent catheterization in paraplegic patients.
Topics: Adolescent; Adult; Aged; Ascorbic Acid; Bethanechol Compounds; Humans; Male; Methenamine; Middle Age | 1967 |
Prevention of urinary tract infection during intermittent catheterization.
Topics: Bacteriuria; Citrates; Humans; Mandelic Acids; Methenamine; Prospective Studies; Spinal Cord Injurie | 1984 |
Formaldehyde generation from methenamine salts in spinal cord injury.
Topics: Anti-Infective Agents, Urinary; Ascorbic Acid; Bacteriuria; Formaldehyde; Hippurates; Humans; Hydrog | 1984 |
Ascorbic acid and methenamine mandelate on the urinary pH of spinal cord injury patients.
Topics: Anti-Infective Agents, Urinary; Ascorbic Acid; Humans; Hydrogen-Ion Concentration; Mandelic Acids; M | 1983 |
Bacteriuria during follow-up in patients with spinal cord injury: II Efficacy of antimicrobial suppressants.
Topics: Anti-Infective Agents, Urinary; Bacteriuria; Follow-Up Studies; Humans; Methenamine; Spinal Cord Inj | 1982 |
Recurrent bacteriuria in complete spinal cord injury patients on external condom drainage.
Topics: Anti-Infective Agents, Urinary; Aspirin; Bacteriuria; Evaluation Studies as Topic; Hippurates; Human | 1980 |
Intermittent catheterization to obtain catheter-free bladder function in spinal cord injury.
Topics: Ascorbic Acid; Female; Follow-Up Studies; Humans; Methenamine; Nitrofurantoin; Spinal Cord Injuries; | 1978 |
Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine.
Topics: Bacteriuria; Bed Rest; Female; Humans; Male; Methenamine; Spinal Cord Injuries; Urinary Tract Infect | 1991 |
Bacteriuria in patients with spinal cord injury.
Topics: Aminoglycosides; Bacteriuria; Catheters, Indwelling; Cephalosporins; Drug Combinations; Humans; Male | 1986 |
Intermittent catheterization in patients previously on indwelling catheter drainage.
Topics: Anti-Bacterial Agents; Bacteriuria; Follow-Up Studies; Home Nursing; Humans; Male; Methenamine; Meth | 1973 |
[Spinal cord compression].
Topics: Angiography; Animals; Ascorbic Acid; Blood Vessels; Cats; Female; Humans; Intervertebral Disc; Male; | 1973 |