methenamine has been researched along with Gaucher Disease in 2 studies
Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Gaucher Disease: An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinberg, AG | 1 |
| Bianco, P | 1 |
| Bonucci, E | 1 |
2 other studies available for methenamine and Gaucher Disease
| Article | Year |
|---|---|
Periodic acid--methenamine silver strain for demonstration of cells in Gaucher's disease.
Topics: Gaucher Disease; Humans; Methenamine; Periodic Acid; Silver; Staining and Labeling | 1978 |
Some histochemical observations on Gaucher cells.
Topics: Acid Phosphatase; beta-Glucosidase; Bone Marrow; Concanavalin A; Gaucher Disease; Glucosylceramides; | 1986 |