methenamine and Complication, Postoperative

methenamine has been researched along with Complication, Postoperative in 13 studies

Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.

Research

Studies (13)

Authors

Clinical Trials (4)

Trial Overview

Trial Outcomes

Antibiotic Resistance of Culture-positive Symptomatic UTI

All patients who submit urine cultures that are positive will have sensitivities performed as per standard care. The prevalence of bacterial species and sensitivities will be collected (NCT02358993)
Timeframe: 3 weeks post-operative

Number of Participants With Culture-positive Symptomatic UTI

All patients will be encouraged to submit urine cultures prior to treatment, but this is not always possible. Amongst patients who undergo urine culture as part of standard of care for UTI, the rate of positive cultures will be identified. (NCT02358993)
Timeframe: 3 weeks post-operative

Rate of UTI Consistent With NHSN Criteria

We plan to analyze the prevalence of UTI in this population that meet the definitions of symptomatic UTI and catheter-associated UTI according to the National Healthcare Safety Network criteria. (NCT02358993)
Timeframe: 3 weeks post-operative

Treatment of Clinically Suspected UTI - Per Protocol

This is defined as any symptomatic UTI requiring treatment with antibiotics as determined by the development of 2 or more of the following symptoms, in the absence of vaginal symptoms: urinary frequency; urinary urgency; dysuria; fever over 38oC/100.4oF; suprapubic, flank, or back pain; and/or chills. (NCT02358993)
Timeframe: 3 weeks post-operative

Treatment of Clinically Suspected UTI - Using Intent to Treat Analysis

This is defined as any symptomatic UTI requiring treatment with antibiotics as determined by the development of 2 or more of the following symptoms, in the absence of vaginal symptoms: urinary frequency; urinary urgency; dysuria; fever over 38oC/100.4oF; suprapubic, flank, or back pain; and/or chills. (NCT02358993)
Timeframe: 3 weeks post-operative

Medication Compliance

Compliance assessed by use of a medication diary during treatment period (NCT03287089)
Timeframe: within 30 days of surgery

UTI

Number of participants with a urinary tract infection in the first 30 days following pelvic reconstructive surgery (NCT03287089)
Timeframe: within 30 days of surgery

Trials

8 trials available for methenamine and Complication, Postoperative

Other Studies

5 other studies available for methenamine and Complication, Postoperative