methenamine has been researched along with Alzheimer Disease in 8 studies
Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although typical neuritic plaques were not seen in the cerebellar cortex and the diffuse plaques found in the cerebellum in far smaller proportion than plaques in the prefrontal and parietal cortices of the same cases, Golgi impregnation technique revealed a loss of Purkinje cells and a marked decrease in the density of dendritic arborization." | 1.36 | Morphological changes of the human purkinje cells and deposition of neuritic plaques and neurofibrillary tangles on the cerebellar cortex of Alzheimer's disease. ( Adipepe, LF; Baloyannis, SJ; Costa, VG; Fotiou, DF; Manani, MG; Mavroudis, IA; Njau, SD; Psaroulis, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mavroudis, IA | 1 |
| Fotiou, DF | 1 |
| Adipepe, LF | 1 |
| Manani, MG | 1 |
| Njau, SD | 1 |
| Psaroulis, D | 1 |
| Costa, VG | 1 |
| Baloyannis, SJ | 1 |
| Kondoh, H | 2 |
| Matsushita, M | 1 |
| Kosaka, K | 4 |
| Miyazaki, N | 1 |
| Haga, C | 3 |
| Ikeda, K | 2 |
| Iwabuchi, K | 1 |
| Akiyama, H | 1 |
| Krutsay, M | 1 |
| Kimura, T | 1 |
| Hisano, T | 1 |
| Yoshida, H | 1 |
| Ueda, K | 1 |
| Miyakawa, T | 1 |
| Yamaguchi, H | 2 |
| Hirai, S | 2 |
| Nakazato, Y | 1 |
| Yamazaki, T | 1 |
| Okamoto, K | 1 |
| Oyanagi, S | 1 |
8 other studies available for methenamine and Alzheimer Disease
| Article | Year |
|---|---|
Morphological changes of the human purkinje cells and deposition of neuritic plaques and neurofibrillary tangles on the cerebellar cortex of Alzheimer's disease.
Topics: Alzheimer Disease; Cerebellar Cortex; Cerebral Cortex; Congo Red; Dendritic Spines; Hippocampus; Hum | 2010 |
Staining senile plaques using Bodian's method modified with methenamine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Diseases; Humans; Methenamine; Staining and Labeli | 1993 |
Methenamine-silver staining: a simple and sensitive staining method for senile plaques and neurofibrillary tangles.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Brain; Brain Chemistry; Down Syndrome; Humans; Me | 1994 |
[A new method for simultaneous demonstration of senile plaques and Alzheimer's neurofibrillary tangles].
Topics: Aged; Alzheimer Disease; Brain; Histological Techniques; Humans; Indicators and Reagents; Methenamin | 1994 |
Re-evaluation of classic senile plaques by three-dimensional analysis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain Che | 1994 |
Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain.
Topics: Alzheimer Disease; Amyloidosis; Histological Techniques; Humans; Inclusion Bodies; Methenamine; Stai | 1990 |
Ultrastructural localization of argyrophilic substances in diffuse plaques of Alzheimer-type dementia demonstrated by methenamine silver staining.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Citrates; Citric Acid; Hum | 1991 |
Senile plaque-like structures: observation of a probably unknown type of senile plaque by periodic-acid methenamine silver (PAM) electron microscopy.
Topics: Adult; Aged; Alzheimer Disease; Amyloid; Cerebral Cortex; Humans; Inclusion Bodies; Methenamine; Per | 1989 |