methenamine has been researched along with Acute Disease in 9 studies
Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomised, double blind, long term, crossover study 1 g twice daily of methenamine hippurate was compared with placebo for its preventive effect on recurrent attacks of acute cystitis." | 9.06 | Prevention of recurrent acute cystitis by methenamine hippurate: double blind controlled crossover long term study. ( Cronberg, S; Hellsten, S; Henriksson, L; Persson, KM; Stenberg, P; Welin, CO, 1987) |
| "In a randomised, double blind, long term, crossover study 1 g twice daily of methenamine hippurate was compared with placebo for its preventive effect on recurrent attacks of acute cystitis." | 5.06 | Prevention of recurrent acute cystitis by methenamine hippurate: double blind controlled crossover long term study. ( Cronberg, S; Hellsten, S; Henriksson, L; Persson, KM; Stenberg, P; Welin, CO, 1987) |
| "Acute cystitis is one of the most common health-related problems in the female population." | 1.38 | Urinary tract analgesics for the treatment of patients with acute cystitis: where is the clinical evidence? ( Arnos, P; Athanasiou, S; Falagas, ME; Mavros, MN; Pergialiotis, V; Pitsouni, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pergialiotis, V | 1 |
| Arnos, P | 1 |
| Mavros, MN | 1 |
| Pitsouni, E | 1 |
| Athanasiou, S | 1 |
| Falagas, ME | 1 |
| Seppänen, J | 1 |
| Sulkava, T | 1 |
| Vaalasti, T | 1 |
| Korhonen, H | 1 |
| Räisänen, S | 1 |
| Ylitalo, P | 1 |
| Kotov, IA | 1 |
| Chrapowicki, T | 1 |
| Krzyzanowska-Rogozińska, T | 1 |
| Kurowska, D | 1 |
| Cronberg, S | 1 |
| Welin, CO | 1 |
| Henriksson, L | 1 |
| Hellsten, S | 1 |
| Persson, KM | 1 |
| Stenberg, P | 1 |
| Kasanen, A | 1 |
| Mustakallio, E | 1 |
| Koskinen, EH | 1 |
| Soini, V | 1 |
| Wallerström, BG | 1 |
| Gibson, GR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing Due to New Episodes of Urinary Tract Infections (UTI) in Elderly Women With Recurrent UTI - a Triple- Blinded, Randomized Placebo-controlled Phase IV Study[NCT04077580] | Phase 4 | 400 participants (Anticipated) | Interventional | 2019-11-01 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for methenamine and Acute Disease
| Article | Year |
|---|---|
Combination of trimethoprim and methenamine hippurate in the treatment of acute urinary tract infections.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Double-Blind Method; Drug Co | 1983 |
[Treatment of acute and chronic urinary tract infections in children with an urinary chemotherapeutic agent].
Topics: Acute Disease; Adolescent; Age Factors; Child; Child, Preschool; Chronic Disease; Clinical Trials as | 1975 |
Prevention of recurrent acute cystitis by methenamine hippurate: double blind controlled crossover long term study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Clinical Trials as To | 1987 |
Methenamine hippurate (Hiprex).
Topics: Acute Disease; Bacteria; Chronic Disease; Clinical Trials as Topic; Hippurates; Humans; Methenamine; | 1968 |
5 other studies available for methenamine and Acute Disease
| Article | Year |
|---|---|
Urinary tract analgesics for the treatment of patients with acute cystitis: where is the clinical evidence?
Topics: Acute Disease; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical | 2012 |
[Acute contact allergic dermatitis as a consequence of using degmin].
Topics: Acute Disease; Azepines; Dermatitis, Contact; Disinfectants; Drug Combinations; Humans; Male; Methen | 1980 |
Methenamine hippurate in the treatment of urinary tract infections.
Topics: Acute Disease; Adult; Creatinine; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Inf | 1974 |
[Methamine hippurate--an old antiseptic in a new formula].
Topics: Acute Disease; Administration, Oral; Adult; Chronic Disease; Cystitis; Drug Combinations; Female; Hi | 1972 |
A clinical appraisal of methenamine hippurate in urinary tract infections.
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Cystitis; Female; Hippurates; Humans; Male; | 1970 |