methazolamide has been researched along with Stevens-Johnson Syndrome in 16 studies
Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening adverse drug reactions." | 9.01 | Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis. ( Lohitnavy, M; Tangamornsuksan, W, 2019) |
| "The carbonic anhydrase inhibitor methazolamide infrequently causes Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 7.76 | HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Jee, YK; Kang, HR; Kim, M; Kim, SH; Lee, KW; Park, HW, 2010) |
| "Four cases of Stevens-Johnson syndrome considered to be induced by methazolamide were reported." | 7.69 | Stevens-Johnson syndrome induced by methazolamide treatment. ( Joukou, S; Kagaya, F; Shirato, S; Suzuki, Y, 1997) |
| "Methazolamide is an intraocular pressure-lowering drug that is used in the treatment of glaucoma and other ophthalmologic abnormalities." | 5.43 | HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese. ( Cao, Z; Chen, J; Chen, S; He, L; Luo, H; Luo, X; Sun, X; Xing, Q; Xuan, J; Yang, F; Zhong, H; Zhou, P, 2016) |
| "Methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening adverse drug reactions." | 5.01 | Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis. ( Lohitnavy, M; Tangamornsuksan, W, 2019) |
| " Methazolamide, an anti-glaucomatous agent, could cause severe skin eruptions called Stevens-Johnson syndrome/toxic epidermal necrolyis (SJS/TEN)." | 3.85 | The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells. ( Kishida, K; Maeda, S; Miwa, Y; Sasabe, T; Sugiyama, T; Yamano, M, 2017) |
| "Methazolamide is used to lower intraocular pressure in patients with glaucoma." | 3.81 | Toxic epidermal necrolysis induced by methazolamide in a Chinese-Korean man carrying HLA-B*59:01. ( Dong, Q; Mao, X; Shu, C; Shu, D; Sun, Q; Tie, D; Wang, T; Yan, Y; Yu, M; Zhang, R, 2015) |
| "The carbonic anhydrase inhibitor methazolamide infrequently causes Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.76 | HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Jee, YK; Kang, HR; Kim, M; Kim, SH; Lee, KW; Park, HW, 2010) |
| "Four cases of Stevens-Johnson syndrome considered to be induced by methazolamide were reported." | 3.69 | Stevens-Johnson syndrome induced by methazolamide treatment. ( Joukou, S; Kagaya, F; Shirato, S; Suzuki, Y, 1997) |
| "Stevens-Johnson syndrome (SJS) /toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse drug reactions characterized by widespread epidermal necrosis." | 2.90 | Comprehensive assessment of T cell receptor β repertoire in Stevens-Johnson syndrome/toxic epidermal necrolysis patients using high-throughput sequencing. ( Chen, S; Jiang, M; Luo, X; Qin, S; Tang, C; Wang, L; Xing, Q; Xiong, H; Yang, F; Zhu, H; Zhu, Q, 2019) |
| "Methazolamide is an intraocular pressure-lowering drug that is used in the treatment of glaucoma and other ophthalmologic abnormalities." | 1.43 | HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese. ( Cao, Z; Chen, J; Chen, S; He, L; Luo, H; Luo, X; Sun, X; Xing, Q; Xuan, J; Yang, F; Zhong, H; Zhou, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, PW | 1 |
| Chu, CY | 1 |
| Qiumei, G | 1 |
| Zhengju, C | 1 |
| Xuefei, H | 1 |
| Qu, C | 1 |
| Sohn, KH | 1 |
| Kim, SH | 4 |
| Kang, HR | 2 |
| Shi, L | 1 |
| Li, M | 1 |
| Zhang, F | 1 |
| Wang, B | 1 |
| Yi, X | 1 |
| Ding, Y | 1 |
| Wang, X | 1 |
| Jiang, YY | 1 |
| Nguyen, GH | 1 |
| Jin, HZ | 1 |
| Zeng, YP | 1 |
| Tangamornsuksan, W | 1 |
| Lohitnavy, M | 1 |
| Xiong, H | 1 |
| Wang, L | 1 |
| Jiang, M | 1 |
| Chen, S | 2 |
| Yang, F | 2 |
| Zhu, H | 1 |
| Zhu, Q | 1 |
| Tang, C | 1 |
| Qin, S | 1 |
| Xing, Q | 2 |
| Luo, X | 2 |
| Xuan, J | 1 |
| Chen, J | 1 |
| Zhong, H | 1 |
| Luo, H | 1 |
| Zhou, P | 1 |
| Sun, X | 1 |
| He, L | 1 |
| Cao, Z | 1 |
| Shu, C | 1 |
| Shu, D | 1 |
| Tie, D | 1 |
| Yu, M | 1 |
| Zhang, R | 1 |
| Wang, T | 1 |
| Dong, Q | 1 |
| Sun, Q | 2 |
| Mao, X | 1 |
| Yan, Y | 1 |
| Xu, Y | 1 |
| Wu, M | 1 |
| Sheng, F | 1 |
| Sasabe, T | 1 |
| Maeda, S | 1 |
| Kishida, K | 1 |
| Yamano, M | 1 |
| Miwa, Y | 1 |
| Sugiyama, T | 1 |
| Jee, YK | 2 |
| Kim, S | 1 |
| Lee, JM | 1 |
| Park, HS | 1 |
| Kim, M | 1 |
| Lee, KW | 1 |
| Park, HW | 1 |
| Flach, AJ | 1 |
| Smith, RE | 1 |
| Fraunfelder, FT | 1 |
| Shirato, S | 1 |
| Kagaya, F | 1 |
| Suzuki, Y | 1 |
| Joukou, S | 1 |
| Cotter, JB | 1 |
1 review available for methazolamide and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis.
Topics: Asian People; Drug Hypersensitivity Syndrome; Genetic Predisposition to Disease; Genotype; HLA-B Ant | 2019 |
1 trial available for methazolamide and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Comprehensive assessment of T cell receptor β repertoire in Stevens-Johnson syndrome/toxic epidermal necrolysis patients using high-throughput sequencing.
Topics: Allopurinol; Carbamazepine; Female; High-Throughput Nucleotide Sequencing; Humans; Male; Methazolami | 2019 |
14 other studies available for methazolamide and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Genetic markers for methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis.
Topics: Case-Control Studies; Genetic Markers; Humans; Methazolamide; Stevens-Johnson Syndrome | 2022 |
Association of HLA-C*01:02 with methazolamide-induced toxic epidermal necrolysis.
Topics: Ethnicity; Female; HLA-B Antigens; HLA-C Antigens; Humans; Methazolamide; Minority Groups; Stevens-J | 2022 |
Cross-Reactivity Between Carbonic Anhydrase Inhibitor Confirmed by Lymphocyte Transformation Test: A Case of Methazolamide-Induced Toxic Epidermal Necrolysis.
Topics: Carbonic Anhydrase Inhibitors; Humans; Lymphocyte Activation; Methazolamide; Stevens-Johnson Syndrom | 2021 |
A rare case of topical methazolamide ophthalmic solution causing death due to toxic epidermal necrolysis.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Fatal Outcome; Fever; Humans; Male; Me | 2018 |
Methazolamide-induced toxic epidermal necrolysis in a man carrying HLA-B*59:01: successful treatment with infliximab and glucocorticoid.
Topics: Adult; Asian People; China; Drug Therapy, Combination; Glaucoma; Glucocorticoids; HLA-B Antigens; Hu | 2018 |
HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese.
Topics: Adult; Aged; Asian People; Carbonic Anhydrase Inhibitors; Case-Control Studies; Female; Genetic Asso | 2016 |
Toxic epidermal necrolysis induced by methazolamide in a Chinese-Korean man carrying HLA-B*59:01.
Topics: Adult; Alleles; Asian People; Carbonic Anhydrase Inhibitors; China; Genotype; Glaucoma; HLA-B Antige | 2015 |
Methazolamide-induced toxic epidermal necrolysis in a Chinese woman with HLA-B5901.
Topics: Carbonic Anhydrase Inhibitors; China; Female; Glaucoma; Glucocorticoids; HLA-B Antigens; Humans; Inj | 2015 |
The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells.
Topics: Acetylcysteine; beta-Naphthoflavone; Carbonic Anhydrase Inhibitors; Cell Line; Chromatography, High | 2017 |
CD8
Topics: Autoantibodies; CD8-Positive T-Lymphocytes; Disease Susceptibility; Genotype; HLA Antigens; Humans; | 2017 |
HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis.
Topics: Adult; Alleles; Female; Genotype; HLA-B Antigens; Humans; Male; Methazolamide; Middle Aged; Republic | 2010 |
Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Eye Diseases; Female; Follow-Up Studies; Humans; Japan; | 1995 |
Stevens-Johnson syndrome induced by methazolamide treatment.
Topics: Adult; Carbonic Anhydrase Inhibitors; Corneal Diseases; Corneal Transplantation; Female; Glaucoma; H | 1997 |
Methazolamide-induced Stevens-Johnson syndrome: a warning!
Topics: Carbonic Anhydrase Inhibitors; Female; Humans; Intraocular Pressure; Methazolamide; Middle Aged; Ocu | 1998 |