methazolamide and Drug-Related Side Effects and Adverse Reactions studies

methazolamide and Drug-Related Side Effects and Adverse Reactions

Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.

Research Excerpts

Excerpt	Relevance	Reference
"The multiple drug interactions in which CAIs are involved should be carefully considered when such drugs are used in combination with the drug classes mentioned above, as the risks of developing toxicity and serious side effects if the dosages are not adjusted are high."	2.53	Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. ( Supuran, CT, 2016)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

2 (100.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Liu, Z	1
Shi, Q	1
Ding, D	1
Kelly, R	1
Fang, H	1
Tong, W	1
Supuran, CT	1

Studies

Liu, Z

Shi, Q

Ding, D

Kelly, R

Fang, H

Tong, W

Supuran, CT

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
An Open-label, Multi-center, Phase 1b Study to Investigate the Safety and Tolerability of SLC-0111 (WBI-5111) in Combination With Gemcitabine in Metastatic Pancreatic Ductal Adenocarcinoma Subjects Positive for Carbonic Anhydrase IX[NCT03450018]	Phase 1/Phase 2	30 participants (Anticipated)	Interventional	2019-01-10	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

An Open-label, Multi-center, Phase 1b Study to Investigate the Safety and Tolerability of SLC-0111 (WBI-5111) in Combination With Gemcitabine in Metastatic Pancreatic Ductal Adenocarcinoma Subjects Positive for Carbonic Anhydrase IX[NCT03450018]

Phase 1/Phase 2

30 participants (Anticipated)

Interventional

2019-01-10

Recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methazolamide and Drug-Related Side Effects and Adverse Reactions

Article	Year
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert opinion on drug metabolism & toxicology, 2016, Volume: 12, Issue:4 Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal;	2016

Article

Year

Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.

Expert opinion on drug metabolism & toxicology, 2016, Volume: 12, Issue:4

Topics: Acetazolamide; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antibodies, Monoclonal;

2016

Other Studies

1 other study available for methazolamide and Drug-Related Side Effects and Adverse Reactions

Article	Year
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da	2011

Article

Year

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology, 2011, Volume: 7, Issue:12

Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011