methazolamide has been researched along with Disease Models, Animal in 8 studies
Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Inhibition of CAII by acetazolamide or methazolamide delayed the decrease in the intracellular pH observed during hypercapnia in cultured AECI, AECII, and AECI-like cells." | 3.74 | Carbonic anhydrase II and alveolar fluid reabsorption during hypercapnia. ( Briva, A; Chen, J; Lecuona, E; Sznajder, JI; Welch, LC, 2008) |
| " Benzolamide dose-dependently inhibited CO(2)-induced hyperemia and at 100 nmol/L inhibited CO(2)-induced intracellular acidification." | 3.73 | Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum. ( Akiba, Y; Engel, E; Ghayouri, S; Guth, PH; Kaunitz, JD; Mizumori, M; Swenson, ER; Takeuchi, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scozzafava, A | 2 |
| Briganti, F | 1 |
| Mincione, G | 1 |
| Menabuoni, L | 1 |
| Mincione, F | 2 |
| Supuran, CT | 2 |
| Starnotti, M | 1 |
| Masini, E | 1 |
| Bacciottini, L | 1 |
| Scrivanti, C | 1 |
| Casini, A | 1 |
| Vullo, D | 1 |
| Li, M | 1 |
| Wang, W | 1 |
| Mai, H | 1 |
| Zhang, X | 1 |
| Wang, J | 1 |
| Gao, Y | 1 |
| Wang, Y | 1 |
| Deng, G | 1 |
| Gao, L | 1 |
| Zhou, S | 1 |
| Chen, Q | 1 |
| Wang, X | 2 |
| Zhu, S | 1 |
| Pei, Z | 1 |
| Drozda, M | 1 |
| Stavrovskaya, IG | 1 |
| Del Signore, SJ | 1 |
| Cormier, K | 1 |
| Shimony, EM | 1 |
| Wang, H | 1 |
| Ferrante, RJ | 1 |
| Kristal, BS | 1 |
| Friedlander, RM | 1 |
| Kiwull-Schöne, HF | 1 |
| Li, Y | 1 |
| Kiwull, PJ | 1 |
| Teppema, LJ | 1 |
| Giacomotto, J | 1 |
| Pertl, C | 1 |
| Borrel, C | 1 |
| Walter, MC | 1 |
| Bulst, S | 1 |
| Johnsen, B | 1 |
| Baillie, DL | 1 |
| Lochmüller, H | 1 |
| Thirion, C | 1 |
| Ségalat, L | 1 |
| Akiba, Y | 1 |
| Ghayouri, S | 1 |
| Takeuchi, T | 1 |
| Mizumori, M | 1 |
| Guth, PH | 1 |
| Engel, E | 1 |
| Swenson, ER | 1 |
| Kaunitz, JD | 1 |
| Chen, J | 1 |
| Lecuona, E | 1 |
| Briva, A | 1 |
| Welch, LC | 1 |
| Sznajder, JI | 1 |
8 other studies available for methazolamide and Disease Models, Animal
| Article | Year |
|---|---|
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Membrane | 1999 |
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
Topics: Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Disease Models, | 2005 |
Methazolamide improves neurological behavior by inhibition of neuron apoptosis in subarachnoid hemorrhage mice.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Caspase 3; Cerebral Cortex; Cognition Disorder | 2016 |
Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease.
Topics: Animals; Brain; Carbonic Anhydrase Inhibitors; Caspases; Cell Death; Cell Line, Transformed; Cytochr | 2008 |
Methazolamide does not impair respiratory work performance in anesthetized rabbits.
Topics: Anesthesia, General; Animals; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Disease Models, Animal; | 2009 |
Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbonic Anhydrase Inhibitors; Car | 2009 |
Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum.
Topics: Amiloride; Animals; Benzolamide; Blood Flow Velocity; Capsaicin; Carbon Dioxide; Carbonic Anhydrase | 2006 |
Carbonic anhydrase II and alveolar fluid reabsorption during hypercapnia.
Topics: Acetazolamide; Animals; Bronchoalveolar Lavage Fluid; Carbon Dioxide; Carbonic Anhydrase II; Carboni | 2008 |