Page last updated: 2024-10-30

methazolamide and Altitude Sickness

methazolamide has been researched along with Altitude Sickness in 6 studies

Methazolamide: A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

Altitude Sickness: Multiple symptoms associated with reduced oxygen at high ALTITUDE.

Research Excerpts

ExcerptRelevanceReference
"What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and theophylline (300 BID) improved arterial oxygen saturation but did not reduce symptoms of AMS and impaired aerobic performance."8.02Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia. ( Davis, C; Evero, O; Gronewold, J; Nichols, AJ; Reitinger, J; Roach, RC; Subudhi, AW; Van-Houten, SJ, 2021)
"What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and theophylline (300 BID) improved arterial oxygen saturation but did not reduce symptoms of AMS and impaired aerobic performance."4.02Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia. ( Davis, C; Evero, O; Gronewold, J; Nichols, AJ; Reitinger, J; Roach, RC; Subudhi, AW; Van-Houten, SJ, 2021)
"Methazolamide can increase systemic metabolic acidosis and sequentially improve ventilation and oxygenation level."2.66Methazolamide in high-altitude illnesses. ( Jiang, Y; Lu, H; Zhang, H, 2020)
"Methazolamide (150 mg/d) was as effective as acetazolamide (500 mg/d) in preventing the symptoms of acute mountain sickness in 20 subjects ascending to 4985 m."2.65Methazolamide and acetazolamide in acute mountain sickness. ( Bradwell, AR; Fletcher, RF; Wright, AD, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Lu, H1
Zhang, H1
Jiang, Y1
Subudhi, AW1
Evero, O1
Reitinger, J1
Davis, C1
Gronewold, J1
Nichols, AJ1
Van-Houten, SJ1
Roach, RC1
Forster, P1
Wright, AD1
Bradwell, AR1
Fletcher, RF1
Mackintosh, JH1
Thomas, DJ1
Olive, JE1
Chesner, IM1
Knight, RJ1

Reviews

1 review available for methazolamide and Altitude Sickness

ArticleYear
Methazolamide in high-altitude illnesses.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, May-30, Volume: 148

    Topics: Acetazolamide; Altitude Sickness; Humans; Hypoxia; Methazolamide; Oxidative Stress; Oxygen; Polycyth

2020

Trials

2 trials available for methazolamide and Altitude Sickness

ArticleYear
Methazolamide in acute mountain sickness.
    Lancet (London, England), 1982, May-29, Volume: 1, Issue:8283

    Topics: Acetazolamide; Altitude Sickness; Clinical Trials as Topic; Humans; Hypoxia; Methazolamide; Thiadiaz

1982
Methazolamide and acetazolamide in acute mountain sickness.
    Aviation, space, and environmental medicine, 1983, Volume: 54, Issue:7

    Topics: Acetazolamide; Adult; Altitude Sickness; Clinical Trials as Topic; Female; Humans; Hypoxia; Male; Me

1983

Other Studies

3 other studies available for methazolamide and Altitude Sickness

ArticleYear
Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia.
    Experimental physiology, 2021, Volume: 106, Issue:1

    Topics: Acute Disease; Adult; Altitude; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Exercise

2021
Statement on high-altitude illnesses. An Advisory Committee Statement (ACS).
    Canada communicable disease report = Releve des maladies transmissibles au Canada, 2007, Apr-01, Volume: 33, Issue:ACS-5

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Canada; Dexamethasone; Humans; Methazolamide; Nifed

2007
The effect of altitude on tests of reaction time and alertness.
    Aviation, space, and environmental medicine, 1988, Volume: 59, Issue:3

    Topics: Acetazolamide; Adult; Altitude; Altitude Sickness; Arousal; Humans; Methazolamide; Middle Aged; Moun

1988