methapyrilene has been researched along with Abnormalities, Autosome in 4 studies
Methapyrilene: Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.
methapyrilene : A member of the class of ethylenediamine derivatives that is ethylenediamine in which one of the nitrogens is substituted by two methyl groups, and the other nitrogen is substituted by a 2-pyridyl group and a (2-thienyl)methyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HK | 1 |
| Kim, YH | 1 |
| Roh, JK | 1 |
| Casciano, DA | 1 |
| Talaska, G | 1 |
| Clive, D | 3 |
| Turner, NT | 1 |
| Woolley, JL | 1 |
| Hozier, JC | 1 |
| Sawyer, JR | 1 |
4 other studies available for methapyrilene and Abnormalities, Autosome
| Article | Year |
|---|---|
Clastogenicity of methapyrilene hydrochloride in cultured Chinese hamster cells.
Topics: Animals; CHO Cells; Chromosome Aberrations; Cricetinae; Hydrogen-Ion Concentration; Methapyrilene; M | 1994 |
The potent hepatocarcinogen methapyrilene induces mutations in L5178Y mouse lymphoma cells in the apparent absence of DNA adduct formation.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chromosome Aberrations; Colony-Forming Units Assay; Dim | 1991 |
Methapyrilene is a genotoxic carcinogen: studies on methapyrilene and pyrilamine in the L5178Y/TK +/- mouse lymphoma assay.
Topics: Aminopyridines; Animals; Biotransformation; Carcinogens; Chromosome Aberrations; Leukemia L5178; Met | 1987 |
Mutagenicity in drug development: interpretation and significance of test results.
Topics: Acyclovir; Animals; Carcinogens; Chromosome Aberrations; Costs and Cost Analysis; DNA Repair; False | 1985 |