methantheline has been researched along with Hyperhidrosis in 13 studies
Methantheline: A quaternary ammonium compound that acts as an antimuscarinic agent. It has been used in the treatment of PEPTIC ULCER, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of HYPERHIDROSIS.
Hyperhidrosis: Excessive sweating. In the localized type, the most frequent sites are the palms, soles, axillae, inguinal folds, and the perineal area. Its chief cause is thought to be emotional. Generalized hyperhidrosis may be induced by a hot, humid environment, by fever, or by vigorous exercise.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the efficacy and safety of methantheline bromide (MB) in the treatment of axillary and palmar-axillary hyperhidrosis." | 9.17 | Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. ( Berensmeier, A; Dirschka, T; Fischer, T; Hamm, H; Müller, C; Reich, K; Rzany, B, 2013) |
| "To assess the efficacy and safety of methantheline bromide (MB) in the treatment of axillary and palmar-axillary hyperhidrosis." | 5.17 | Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. ( Berensmeier, A; Dirschka, T; Fischer, T; Hamm, H; Müller, C; Reich, K; Rzany, B, 2013) |
| " No serious adverse events were reported." | 2.71 | [Randomized, placebo-controlled, double blind clinical trial for the evaluation of the efficacy and safety of oral methantheliniumbromide (Vagantin) in the treatment of focal hyperhidrosis]. ( Hund, M; Rzany, B; Sinkgraven, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jäger-Becker, D | 1 |
| Müller, C | 2 |
| Augustin, M | 1 |
| Berensmeier, A | 1 |
| Hamm, H | 1 |
| Dirschka, T | 1 |
| Reich, K | 1 |
| Fischer, T | 1 |
| Rzany, B | 3 |
| ZUPKO, AG | 2 |
| PROKOP, LN | 1 |
| ROBINSON, HM | 1 |
| AMYOT, R | 1 |
| GRIMSON, KS | 1 |
| LYONS, CK | 1 |
| WATKINS, WT | 1 |
| CALLAWAY, JL | 1 |
| Hund, M | 1 |
| Sinkgraven, R | 1 |
| Fuchslocher, M | 1 |
2 trials available for methantheline and Hyperhidrosis
| Article | Year |
|---|---|
Efficacy and safety of methantheline bromide (Vagantin(®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Axilla; Dose-Response Relationship, Drug; Double-Blind Method; Female; Huma | 2013 |
[Randomized, placebo-controlled, double blind clinical trial for the evaluation of the efficacy and safety of oral methantheliniumbromide (Vagantin) in the treatment of focal hyperhidrosis].
Topics: Administration, Oral; Adolescent; Adult; Cholinergic Antagonists; Double-Blind Method; Female; Germa | 2004 |
11 other studies available for methantheline and Hyperhidrosis
| Article | Year |
|---|---|
[In process].
Topics: Administration, Oral; Axilla; Drug Approval; Germany; Humans; Hyperhidrosis; Methantheline; Muscarin | 2016 |
[Hyperhidrosis - an underestimated comorbidity. Great discomfort should not be tolerated].
Topics: Adult; Comorbidity; Female; Germany; Guideline Adherence; Humans; Hyperhidrosis; Male; Methantheline | 2014 |
[Hyperhidrosis. Effective reduced sweating with methantheline bromide].
Topics: Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Guideline Adherence; Humans; | 2012 |
Willingness-to-pay and patient-defined benefits in the treatment of hyperhidrosis: results from the first German health services research study in hyperhidrosis.
Topics: Dermatologic Agents; Financing, Personal; Germany; Health Care Surveys; Humans; Hyperhidrosis; Metha | 2013 |
[Managing hyperhidrosis].
Topics: Aluminum Chloride; Aluminum Compounds; Astringents; Botulinum Toxins, Type A; Bridged-Ring Compounds | 2012 |
A comparative study of prantal and banthine in hyperhidrosis.
Topics: Humans; Hyperhidrosis; Methantheline; Parasympatholytics; Piperidines; Quaternary Ammonium Compounds | 1952 |
A treatment for hyperhidrosis.
Topics: Humans; Hyperhidrosis; Methantheline; Quaternary Ammonium Compounds; Sweating | 1953 |
[Recent medications in the control of perspiration odor and hyperhidrosis].
Topics: Chlorophyll; Humans; Hyperhidrosis; Methantheline; Odorants; Quaternary Ammonium Compounds; Sweat; S | 1951 |
An evaluation of banthine in hyperhidrosis.
Topics: Hyperhidrosis; Methantheline; Parasympatholytics; Quaternary Ammonium Compounds; Sweating | 1952 |
Successful treatment of hyperhidrosis using banthine.
Topics: Humans; Hyperhidrosis; Methantheline; Quaternary Ammonium Compounds; Sweat Glands | 1950 |
[Oral anticholinergic therapy of focal hyperhidrosis with methanthelinium bromide (Vagantin). Initial data on effectiveness].
Topics: Administration, Oral; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Administration | 2002 |