Page last updated: 2024-10-19

methanol and Parkinson Disease

methanol has been researched along with Parkinson Disease in 7 studies

Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Methanol was studied because its toxicity resembles the symptoms of PD and the symptoms are relieved by L-dopa meaning that MeOH targets the NSDA system."1.38Prenatal exposure to methanol as a dopamine system sensitization model in C57BL/6J mice. ( Charlton, CG; King, J; Mackey, VR; Muthian, G; Smith, M, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Lawal, BA1
Ayipo, YO1
Adekunle, AO1
Amali, MO1
Badeggi, UM1
Alananzeh, WA1
Mordi, MN1
Liu, Y1
Li, H1
Li, Y1
Yang, M1
Wang, X1
Peng, Y1
Sengupta, T1
Vinayagam, J1
Nagashayana, N1
Gowda, B1
Jaisankar, P1
Mohanakumar, KP1
Mackey, VR1
Muthian, G1
Smith, M1
King, J1
Charlton, CG1
Cárcaba, V1
García Amorín, Z1
Rodríguez Junquera, R1
Velasco, L1
Diemath, HE1
Enge, S1
Lechner, H1
Romano, F1

Other Studies

7 other studies available for methanol and Parkinson Disease

ArticleYear
Phytoconstituents of Datura metel extract improved motor coordination in haloperidol-induced cataleptic mice: Dual-target molecular docking and behavioural studies.
    Journal of ethnopharmacology, 2023, Jan-10, Volume: 300

    Topics: alpha-Synuclein; Animals; Antioxidants; Antiparkinson Agents; Atropine Derivatives; Carbidopa; Choli

2023
Velvet Antler Methanol Extracts Ameliorate Parkinson's Disease by Inhibiting Oxidative Stress and Neuroinflammation: From
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: alpha-Synuclein; Animals; Antlers; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Neur

2021
Antiparkinsonian effects of aqueous methanolic extract of Hyoscyamus niger seeds result from its monoamine oxidase inhibitory and hydroxyl radical scavenging potency.
    Neurochemical research, 2011, Volume: 36, Issue:1

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Free Radical Scavengers; Hu

2011
Prenatal exposure to methanol as a dopamine system sensitization model in C57BL/6J mice.
    Life sciences, 2012, Nov-02, Volume: 91, Issue:19-20

    Topics: alpha-Synuclein; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Corpus Striatum; D

2012
[Parkinsonism and putaminal lesion from methanol intoxication].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:8

    Topics: Basal Ganglia Diseases; Female; Humans; Methanol; Middle Aged; Parkinson Disease; Putamen

2002
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
    Confinia neurologica, 1970, Volume: 32, Issue:2

    Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir

1970
[Therapeutic experience with the use of piritinol (Encephabol) in geriatrics].
    Minerva medica, 1970, Jun-27, Volume: 61, Issue:51

    Topics: Aged; Asthenia; Cognition Disorders; Dementia; Epilepsy; Female; Humans; Intracranial Arterioscleros

1970