methanol has been researched along with Parkinson Disease in 7 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Excerpt | Relevance | Reference |
---|---|---|
"Methanol was studied because its toxicity resembles the symptoms of PD and the symptoms are relieved by L-dopa meaning that MeOH targets the NSDA system." | 1.38 | Prenatal exposure to methanol as a dopamine system sensitization model in C57BL/6J mice. ( Charlton, CG; King, J; Mackey, VR; Muthian, G; Smith, M, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (28.57) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 2 (28.57) | 2.80 |
Authors | Studies |
---|---|
Lawal, BA | 1 |
Ayipo, YO | 1 |
Adekunle, AO | 1 |
Amali, MO | 1 |
Badeggi, UM | 1 |
Alananzeh, WA | 1 |
Mordi, MN | 1 |
Liu, Y | 1 |
Li, H | 1 |
Li, Y | 1 |
Yang, M | 1 |
Wang, X | 1 |
Peng, Y | 1 |
Sengupta, T | 1 |
Vinayagam, J | 1 |
Nagashayana, N | 1 |
Gowda, B | 1 |
Jaisankar, P | 1 |
Mohanakumar, KP | 1 |
Mackey, VR | 1 |
Muthian, G | 1 |
Smith, M | 1 |
King, J | 1 |
Charlton, CG | 1 |
Cárcaba, V | 1 |
García Amorín, Z | 1 |
Rodríguez Junquera, R | 1 |
Velasco, L | 1 |
Diemath, HE | 1 |
Enge, S | 1 |
Lechner, H | 1 |
Romano, F | 1 |
7 other studies available for methanol and Parkinson Disease
Article | Year |
---|---|
Phytoconstituents of Datura metel extract improved motor coordination in haloperidol-induced cataleptic mice: Dual-target molecular docking and behavioural studies.
Topics: alpha-Synuclein; Animals; Antioxidants; Antiparkinson Agents; Atropine Derivatives; Carbidopa; Choli | 2023 |
Velvet Antler Methanol Extracts Ameliorate Parkinson's Disease by Inhibiting Oxidative Stress and Neuroinflammation: From
Topics: alpha-Synuclein; Animals; Antlers; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Neur | 2021 |
Antiparkinsonian effects of aqueous methanolic extract of Hyoscyamus niger seeds result from its monoamine oxidase inhibitory and hydroxyl radical scavenging potency.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Free Radical Scavengers; Hu | 2011 |
Prenatal exposure to methanol as a dopamine system sensitization model in C57BL/6J mice.
Topics: alpha-Synuclein; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Corpus Striatum; D | 2012 |
[Parkinsonism and putaminal lesion from methanol intoxication].
Topics: Basal Ganglia Diseases; Female; Humans; Methanol; Middle Aged; Parkinson Disease; Putamen | 2002 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Cir | 1970 |
[Therapeutic experience with the use of piritinol (Encephabol) in geriatrics].
Topics: Aged; Asthenia; Cognition Disorders; Dementia; Epilepsy; Female; Humans; Intracranial Arterioscleros | 1970 |