methanol has been researched along with Optic Nerve Diseases in 45 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 34-years-old floor-layer developed optic neuropathy and motor neuron disease after being accidentally exposed to a solvent mixture containing methanol and other substances." | 7.72 | Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture. ( Chiò, A; Discalzi, G; Herrero Hernandez, E; Mora, G; Pira, E; Valentini, C, 2004) |
| "To present results of electrophysiologic investigations of the visual toxicity observed during the early stage of methanol poisoning." | 7.70 | Evoked potentials investigation of visual dysfunction after methanol poisoning. ( Beguin, C; Boschi, A; de Tourtchaninoff, M; Guérit, JM; Hantson, P; Mahieu, P; Simoens, G, 1999) |
| "Methanol was isolated from a sample of the beverage with gas chromatography." | 5.37 | Methanol poisoning: two case studies of blindness in Indonesia. ( Bron, AM; Creuzot-Garcher, C; Koehrer, P, 2011) |
| "A 34-years-old floor-layer developed optic neuropathy and motor neuron disease after being accidentally exposed to a solvent mixture containing methanol and other substances." | 3.72 | Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture. ( Chiò, A; Discalzi, G; Herrero Hernandez, E; Mora, G; Pira, E; Valentini, C, 2004) |
| "We report a case of methanol blindness." | 3.71 | [Bilateral optic neuropathy in acute methanol intoxication. A case report]. ( Blain, P; Gaudric, A; Krivosic, V; Vignal-Clermont, C, 2001) |
| "To present results of electrophysiologic investigations of the visual toxicity observed during the early stage of methanol poisoning." | 3.70 | Evoked potentials investigation of visual dysfunction after methanol poisoning. ( Beguin, C; Boschi, A; de Tourtchaninoff, M; Guérit, JM; Hantson, P; Mahieu, P; Simoens, G, 1999) |
| "The authors report four cases of methanol poisoning, two of which suffering acute bilateral optic neuropathy which secondarily leads to optic atrophy." | 3.66 | [Optic neuropathy in acute poisoning with methanol]. ( Arne, JL; Bec, P; Bensouda, J; Dupeyron, G; Maillard, P; Sekkat, A, 1982) |
| "Methanol is an important public health and environmental concern because of the selective actions of its neurotoxic metabolite, formic acid, on the retina, optic nerve and central nervous system." | 2.41 | Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity. ( Eells, JT; Henry, MM; Lewandowski, MF; Murray, TG; Seme, MT, 2000) |
| "Methanol poisoning can cause an optic neuropathy that is usually severe and irreversible and often occurs after ingestion of illicit or homemade alcoholic beverages." | 1.48 | Erythropoietin in Treatment of Methanol Optic Neuropathy. ( Haghighi, A; Kashkouli, MB; Naderi, A; Pakdel, F; Pirmarzdashti, N; Sanjari, MS, 2018) |
| "Methanol poisoning has become very uncommon in Australasia with regulations that have reduced its retail availability." | 1.38 | Toxic cocktail: methanol poisoning in a tourist to Indonesia. ( Gee, P; Martin, E, 2012) |
| "Methanol was isolated from a sample of the beverage with gas chromatography." | 1.37 | Methanol poisoning: two case studies of blindness in Indonesia. ( Bron, AM; Creuzot-Garcher, C; Koehrer, P, 2011) |
| "Methanol is a highly toxic substance which is used as an industrial solvent and in automotive antifreeze." | 1.28 | Partly reversible visual failure with methanol toxicity. ( O'Day, J; Stelmach, MZ, 1992) |
| "The difficulties of identifying wooden foreign bodies as well as the topographical problems involved with the approach to the superior orbital fissure are discussed." | 1.28 | A wooden foreign body penetrating the superior orbital fissure. ( Hassler, W; Petersen, D; Zentner, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (22.22) | 18.7374 |
| 1990's | 5 (11.11) | 18.2507 |
| 2000's | 8 (17.78) | 29.6817 |
| 2010's | 17 (37.78) | 24.3611 |
| 2020's | 5 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Liberski, S | 1 |
| Kaluzny, BJ | 1 |
| Kocięcki, J | 1 |
| Baj, J | 1 |
| Forma, A | 1 |
| Kobak, J | 1 |
| Tyczyńska, M | 1 |
| Dudek, I | 1 |
| Maani, A | 1 |
| Teresiński, G | 1 |
| Buszewicz, G | 1 |
| Januszewski, J | 1 |
| Flieger, J | 1 |
| Jafarizadeh, A | 1 |
| Homaie, M | 1 |
| Abdollahi, M | 1 |
| Niyousha, M | 1 |
| Chraibi, F | 1 |
| Moutei, H | 1 |
| Bennis, A | 1 |
| Abdellaoui, M | 1 |
| Andaloussi Benatiya, I | 1 |
| Khalili, MR | 1 |
| Sadati, MS | 1 |
| Jahanbani-Ardakani, H | 1 |
| Zamani, N | 1 |
| Hassanian-Moghaddam, H | 1 |
| Shojaei, M | 1 |
| Rahimian, S | 1 |
| Pakdel, F | 1 |
| Sanjari, MS | 1 |
| Naderi, A | 1 |
| Pirmarzdashti, N | 1 |
| Haghighi, A | 1 |
| Kashkouli, MB | 1 |
| Nurieva, O | 3 |
| Diblik, P | 3 |
| Kuthan, P | 3 |
| Sklenka, P | 3 |
| Meliska, M | 3 |
| Bydzovsky, J | 3 |
| Heissigerova, J | 3 |
| Urban, P | 3 |
| Kotikova, K | 3 |
| Navratil, T | 3 |
| Komarc, M | 3 |
| Seidl, Z | 3 |
| Vaneckova, M | 3 |
| Pelclova, D | 2 |
| Zakharov, S | 3 |
| Grzybowski, A | 2 |
| Kanclerz, P | 1 |
| Hubacek, JA | 1 |
| Hlusicka, J | 1 |
| Vojtova, L | 1 |
| Bron, A | 1 |
| Koehrer, P | 2 |
| Creuzot-Garcher, C | 2 |
| Sanaei-Zadeh, H | 2 |
| Tanrivermis Sayit, A | 1 |
| Aslan, K | 1 |
| Elmali, M | 1 |
| Gungor, I | 1 |
| Pakravan, M | 2 |
| Esfandiari, H | 1 |
| Sanjari, N | 2 |
| Ghahari, E | 1 |
| Adinoff, B | 1 |
| Wasinska-Borowiec, W | 1 |
| Aghdam, KA | 1 |
| Saari, JM | 1 |
| Bhatia, R | 1 |
| Kumar, M | 1 |
| Garg, A | 1 |
| Nanda, A | 1 |
| Abrishami, M | 2 |
| Khalifeh, M | 1 |
| Shoayb, M | 1 |
| Bron, AM | 1 |
| Gee, P | 1 |
| Martin, E | 1 |
| BENTON, CD | 1 |
| CALHOUN, EP | 1 |
| BURK, M | 1 |
| LASCO, F | 1 |
| Chiò, A | 1 |
| Herrero Hernandez, E | 1 |
| Mora, G | 1 |
| Valentini, C | 1 |
| Discalzi, G | 1 |
| Pira, E | 1 |
| Nagasawa, H | 1 |
| Wada, M | 1 |
| Koyama, S | 1 |
| Kawanami, T | 1 |
| Kurita, K | 1 |
| Kato, T | 1 |
| Winnik, L | 1 |
| Radomska, M | 1 |
| Woś, M | 1 |
| Pach, D | 1 |
| Tachfouti, S | 1 |
| Boutimzine, N | 1 |
| Cherkaoui, O | 1 |
| Mohcine, Z | 1 |
| Sharpe, JA | 1 |
| Hostovsky, M | 1 |
| Bilbao, JM | 1 |
| Rewcastle, NB | 1 |
| Sekkat, A | 1 |
| Maillard, P | 1 |
| Dupeyron, G | 1 |
| Bensouda, J | 1 |
| Arne, JL | 1 |
| Bec, P | 1 |
| Sullivan-Mee, M | 1 |
| Solis, K | 1 |
| Sharma, M | 1 |
| Volpe, NJ | 1 |
| Dreyer, EB | 1 |
| Hantson, P | 1 |
| de Tourtchaninoff, M | 1 |
| Simoens, G | 1 |
| Mahieu, P | 1 |
| Boschi, A | 1 |
| Beguin, C | 1 |
| Guérit, JM | 1 |
| Eells, JT | 1 |
| Henry, MM | 1 |
| Lewandowski, MF | 1 |
| Seme, MT | 1 |
| Murray, TG | 1 |
| Krivosic, V | 1 |
| Vignal-Clermont, C | 1 |
| Blain, P | 1 |
| Gaudric, A | 1 |
| Sodhi, PK | 1 |
| Goyal, JL | 1 |
| Mehta, DK | 1 |
| Dethlefs, R | 1 |
| Naraqi, S | 1 |
| Stelmach, MZ | 1 |
| O'Day, J | 1 |
| Hayreh, SS | 1 |
| Naeser, P | 1 |
| Ogawa, Y | 1 |
| Takatsuki, R | 1 |
| Uema, T | 1 |
| Seki, Y | 1 |
| Hiramatsu, K | 1 |
| Okayama, A | 1 |
| Morimoto, K | 1 |
| Kaneko, Z | 1 |
| Indeĭkin, EN | 1 |
| Zentner, J | 1 |
| Hassler, W | 1 |
| Petersen, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.[NCT05748561] | Phase 2/Phase 3 | 18 participants (Anticipated) | Interventional | 2022-04-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for methanol and Optic Nerve Diseases
| Article | Year |
|---|---|
Methanol-induced optic neuropathy: a still-present problem.
Topics: Animals; Axons; Formates; Humans; Methanol; Mitochondria; Optic Nerve; Optic Nerve Diseases; Oxidati | 2022 |
Toxic and Nutritional Optic Neuropathies-An Updated Mini-Review.
Topics: Humans; Malnutrition; Methanol; Optic Nerve; Optic Nerve Diseases; Vision Disorders | 2022 |
An Updated Review on the Most Common Agents Causing Toxic Optic Neuropathies.
Topics: Amiodarone; Erythropoietin; Ethambutol; Humans; Linezolid; Methanol; Optic Nerve Diseases; Phosphodi | 2017 |
Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity.
Topics: Animals; Disease Models, Animal; Folic Acid; Formates; Humans; Methanol; Optic Nerve; Optic Nerve Di | 2000 |
2 trials available for methanol and Optic Nerve Diseases
| Article | Year |
|---|---|
Erythropoietin as an adjunctive treatment for methanol-induced toxic optic neuropathy.
Topics: Administration, Intravenous; Adult; Drug Therapy, Combination; Erythropoietin; Follow-Up Studies; Gl | 2016 |
Therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy.
Topics: Administration, Oral; Adult; Alcoholic Beverages; Emergency Medical Services; Food Contamination; Fu | 2011 |
39 other studies available for methanol and Optic Nerve Diseases
| Article | Year |
|---|---|
Time course study of optical coherence tomography angiography in patients with methanol induced optic neuropathy.
Topics: Angiography; Case-Control Studies; Fluorescein Angiography; Humans; Methanol; Optic Nerve Diseases; | 2023 |
Methanol-induced optic neuropathy.
Topics: Humans; Methanol; Optic Nerve; Optic Nerve Diseases | 2020 |
Outbreak of methanol-induced optic neuropathy amid COVID-19 pandemic.
Topics: COVID-19; Disease Outbreaks; Humans; Iran; Methanol; Optic Nerve Diseases; SARS-CoV-2; Self Medicati | 2021 |
Evaluation of the effect of erythropoietin + corticosteroid versus corticosteroid alone in methanol-induced optic nerve neuropathy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Erythropoietin; Humans; Metha | 2018 |
Erythropoietin in Treatment of Methanol Optic Neuropathy.
Topics: Adolescent; Adult; Erythropoietin; Female; Humans; Infusions, Intravenous; Male; Methanol; Middle Ag | 2018 |
Progressive Chronic Retinal Axonal Loss Following Acute Methanol-induced Optic Neuropathy: Four-Year Prospective Cohort Study.
Topics: Acute Disease; Axons; Brain; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Humans | 2018 |
Reply.
Topics: Humans; Methanol; Optic Nerve Diseases; Optic Neuritis; Prospective Studies | 2018 |
Progressive Chronic Retinal Axonal Loss Following Acute Methanol-Induced Optic Neuropathy: Four-Year Prospective Cohort Study.
Topics: Humans; Methanol; Optic Nerve Diseases; Optic Neuritis; Prospective Studies; Retina | 2018 |
Clinical and genetic determinants of chronic visual pathway changes after methanol - induced optic neuropathy: four-year follow-up study.
Topics: Adult; Apolipoprotein E4; Case-Control Studies; Czech Republic; Evoked Potentials, Visual; Female; F | 2019 |
Response of the authors.
Topics: Blindness; Humans; Male; Methanol; Optic Nerve Diseases | 2014 |
Optical coherence tomography of the macula and optic nerve in methanol-intoxicated patients and the effect of intravenous corticosteroids on their visual disturbances.
Topics: Blindness; Humans; Male; Methanol; Optic Nerve Diseases | 2014 |
Methanol-induced toxic optic neuropathy with diffusion weighted MRI findings.
Topics: Diffusion Magnetic Resonance Imaging; Humans; Male; Methanol; Middle Aged; Optic Nerve Diseases; Per | 2016 |
The costs of prohibition.
Topics: Erythropoietin; Humans; Methanol; Optic Nerve Diseases | 2016 |
Putaminal necrosis due to methanol toxicity.
Topics: Adult; Basal Ganglia Diseases; Blindness; Disease Progression; Humans; Magnetic Resonance Imaging; M | 2008 |
Methanol poisoning: two case studies of blindness in Indonesia.
Topics: Adult; Blindness; Humans; Indonesia; Male; Methanol; Middle Aged; Optic Nerve Diseases | 2011 |
What are the therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy?
Topics: Emergency Medical Services; Glucocorticoids; Humans; Male; Methanol; Methylprednisolone; Neuroprotec | 2012 |
Erythropoietin treatment for methanol optic neuropathy.
Topics: Administration, Intravenous; Administration, Oral; Adult; Anti-Inflammatory Agents; Erythropoietin; | 2012 |
Toxic cocktail: methanol poisoning in a tourist to Indonesia.
Topics: Alcoholic Beverages; Female; Humans; Indonesia; Methanol; Optic Nerve Diseases; Travel; Vision Disor | 2012 |
The ocular effects of methyl alcohol poisoning; report of a catastrophe involving 320 persons.
Topics: Blindness; Disease; Edema; Eye; Humans; Methanol; Optic Nerve; Optic Nerve Diseases; Retina; Retinal | 1953 |
[Chronic industrial methyl alcohol poisoning].
Topics: Alcoholism; Disease; Ethanol; Eye; Humans; Methanol; Optic Nerve; Optic Nerve Diseases | 1957 |
[Pseudoglaucoma after poisoning by methyl alcohol].
Topics: Disease; Ethanol; Eye; Eye Diseases, Hereditary; Humans; Methanol; Optic Nerve; Optic Nerve Diseases | 1958 |
Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture.
Topics: Adult; Brain Mapping; Humans; Magnetic Resonance Imaging; Male; Methanol; Motor Neuron Disease; Opti | 2004 |
[A case of methanol intoxication with optic neuropathy visualized on STIR sequence of MR images].
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Methanol; Optic Nerve Diseases | 2005 |
[The CNS damage due to methanol poisoning in the case of 23-year-old male patient addicted to organic solvents].
Topics: Acidosis; Adult; Blindness; Humans; Inhalation; Male; Methanol; Optic Nerve Diseases; Solvents; Subs | 2005 |
[Bilateral optic neuropathy from methanol intoxication. A case report].
Topics: Adrenal Cortex Hormones; Adult; Humans; Male; Methanol; Optic Nerve Diseases; Treatment Failure; Vit | 2005 |
Methanol optic neuropathy: a histopathological study.
Topics: Brain Diseases; Cerebral Cortex; Formates; Humans; Male; Methanol; Middle Aged; Myelin Sheath; Optic | 1982 |
[Optic neuropathy in acute poisoning with methanol].
Topics: Adult; Amblyopia; Fluorescein Angiography; Humans; Male; Methanol; Optic Atrophy; Optic Nerve Diseas | 1982 |
Methanol-induced vision loss.
Topics: Acidosis; Adult; Follow-Up Studies; Fundus Oculi; Humans; Male; Methanol; Optic Nerve Diseases; Pupi | 1998 |
Methanol-induced optic nerve cupping.
Topics: Adult; Blindness; Humans; Male; Methanol; Optic Disk; Optic Nerve Diseases | 1999 |
Evoked potentials investigation of visual dysfunction after methanol poisoning.
Topics: Acute Disease; Adolescent; Adult; Aged; Electrophysiology; Ethanol; Evoked Potentials, Visual; Femal | 1999 |
[Bilateral optic neuropathy in acute methanol intoxication. A case report].
Topics: Alcoholic Intoxication; Anti-Inflammatory Agents; Antidotes; Blindness; Hemodiafiltration; Humans; M | 2001 |
Methanol-induced optic neuropathy: treatment with intravenous high dose steroids.
Topics: Adult; Drug Administration Schedule; Glucocorticoids; Humans; Injections, Intravenous; Male; Methano | 2001 |
Ocular manifestations and complications of acute methyl alcohol intoxication.
Topics: Adaptation, Ocular; Blindness; Eye Diseases; Follow-Up Studies; Humans; Male; Methanol; Optic Nerve | 1978 |
Partly reversible visual failure with methanol toxicity.
Topics: Adolescent; Female; Fluorescein Angiography; Fundus Oculi; Humans; Methanol; Optic Atrophy; Optic Ne | 1992 |
Optic nerve involvement in methanol poisoning.
Topics: Animals; Humans; Macaca mulatta; Methanol; Optic Nerve Diseases | 1989 |
Optic nerve involvement in a case of methanol poisoning.
Topics: Adult; Humans; Male; Methanol; Necrosis; Optic Nerve; Optic Nerve Diseases | 1988 |
Acute optic neuropathy induced by thinner sniffing: inhalation of mixed organic solvent containing methyl alcohol and methyl acetate.
Topics: Acetates; Adult; Humans; Male; Methanol; Optic Nerve Diseases; Solvents; Substance-Related Disorders | 1988 |
[Alcohol and vision].
Topics: Adult; Alcoholism; Ethanol; Humans; Male; Methanol; Optic Nerve Diseases; Smoking; Vision Disorders; | 1986 |
A wooden foreign body penetrating the superior orbital fissure.
Topics: Bicycling; Child; Diagnosis, Differential; Escherichia coli Infections; Eye Foreign Bodies; Eye Inju | 1991 |