methanol has been researched along with Experimental Hepatoma in 14 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Together, these findings indicate that OSU-A9 is a potent, orally bioavailable inhibitor of the Akt-NF-kappaB signaling network with a broad spectrum of antitumor activity that includes targets regulating multiple aspects of HCC pathogenesis and progression." | 5.35 | Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma. ( Chen, CS; Kulp, SK; Omar, HA; Patel, T; Sargeant, AM; Wang, D; Weng, JR, 2009) |
| " Together, these findings indicate that OSU-A9 is a potent, orally bioavailable inhibitor of the Akt-NF-kappaB signaling network with a broad spectrum of antitumor activity that includes targets regulating multiple aspects of HCC pathogenesis and progression." | 1.35 | Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma. ( Chen, CS; Kulp, SK; Omar, HA; Patel, T; Sargeant, AM; Wang, D; Weng, JR, 2009) |
| " Unlike the wood beddings, the extracts of the cellulose materials were not found to be toxic to the cells." | 1.28 | Enzyme-inducing and cytotoxic effects of wood-based materials used as bedding for laboratory animals. Comparison by a cell culture study. ( Kärenlampi, S; Pelkonen, K; Törrönen, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, MM | 1 |
| H Borai, I | 1 |
| Ghanem, HM | 1 |
| H Abdel-Halim, A | 1 |
| Mousa, FM | 1 |
| Omar, HA | 1 |
| Sargeant, AM | 1 |
| Weng, JR | 1 |
| Wang, D | 1 |
| Kulp, SK | 1 |
| Patel, T | 1 |
| Chen, CS | 1 |
| Abdel-Hamid, NM | 1 |
| Abdel-Ghany, MI | 1 |
| Nazmy, MH | 1 |
| Amgad, SW | 1 |
| Kim, JH | 1 |
| Lee, JS | 1 |
| Song, KS | 1 |
| Kwon, CS | 1 |
| Kim, YK | 1 |
| Kim, JS | 1 |
| Krøll, J | 1 |
| Larsen, JK | 1 |
| Christensen, IJ | 1 |
| Anilkumar, TV | 1 |
| Golding, M | 1 |
| Edwards, RJ | 1 |
| Lalani, EN | 1 |
| Sarraf, CE | 1 |
| Alison, MR | 1 |
| Miki, K | 1 |
| Xu, M | 1 |
| Gupta, A | 1 |
| Ba, Y | 1 |
| Tan, Y | 1 |
| Al-Refaie, W | 1 |
| Bouvet, M | 1 |
| Makuuchi, M | 1 |
| Moossa, AR | 1 |
| Hoffman, RM | 1 |
| Singh, J | 1 |
| Wiebel, FJ | 1 |
| Matsuda, H | 2 |
| Tong, CN | 2 |
| Kubo, M | 2 |
| Christianson-Heiska, I | 1 |
| Isomaa, B | 1 |
| Huuskonen, SE | 1 |
| Hahn, ME | 1 |
| Lindström-Seppä, P | 1 |
| Jacobs, BB | 1 |
| Dieter, DK | 1 |
| Törrönen, R | 1 |
| Pelkonen, K | 1 |
| Kärenlampi, S | 1 |
1 trial available for methanol and Experimental Hepatoma
| Article | Year |
|---|---|
Can methanolic extract of Nigella sativa seed affect glyco-regulatory enzymes in experimental hepatocellular carcinoma?
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carbon Tetrachloride; Carcinoma, Hepa | 2013 |
13 other studies available for methanol and Experimental Hepatoma
| Article | Year |
|---|---|
The prophylactic and therapeutic effects of Momordica charantia methanol extract through controlling different hallmarks of the hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbon Tetrachloride; Carcinogenesis; Cell Proliferation; | 2018 |
Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; | 2009 |
Polyozellin isolated from Polyozellus multiplex induces phase 2 enzymes in mouse hepatoma cells and differentiation in human myeloid leukaemic cell lines.
Topics: Agaricales; Animals; Anticarcinogenic Agents; Cell Differentiation; Dose-Response Relationship, Drug | 2004 |
Tumor-induced growth-inhibitory activity isolated from the Yoshida ascites fluid by extraction with methanol.
Topics: Animals; Ascitic Fluid; Cell Division; Cell Extracts; Chromatography, Gel; Dinoprostone; Dose-Respon | 1984 |
The resistant hepatocyte model of carcinogenesis in the rat: the apparent independent development of oval cell proliferation and early nodules.
Topics: Acetates; Acetic Acid; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bile Ducts; Blotting, We | 1995 |
Methioninase cancer gene therapy with selenomethionine as suicide prodrug substrate.
Topics: Adenoviridae; Animals; Apoptosis; Carbon-Sulfur Lyases; Cytochrome c Group; Female; Genetic Therapy; | 2001 |
A highly sensitive and rapid fluorometric assay for UDP-glucuronyltransferase using 3-hydroxybenzo (a) pyrene as substrate.
Topics: Animals; Benzopyrenes; Cell Line; Enzyme Activation; Glucuronidase; Glucuronosyltransferase; Kinetic | 1979 |
[Pharmacological study on Panax ginseng C. A. Meyer. XIV. Effect of 70% methanolic extract from red ginseng on the cytocidal effect of mitomycin c against rat ascites hepatoma AH 130].
Topics: Animals; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Chinese Herbal; Female; Liver Neop | 1992 |
[Pharmacological study on Panax ginseng C. A. Meyer. XV. Effects of 70% methanolic extract from red and white ginseng on the antitumor activity of mitomycin C].
Topics: Animals; Carcinoma, Ehrlich Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Chinese | 1992 |
The use of primary hepatocytes from brown trout (Salmo trutta lacustris) and the fish cell lines RTH-149 and ZF-L for in vitro screening of (anti)estrogenic activity of wood extractives.
Topics: Abietanes; Animals; Betula; Carboxylic Acids; Cell Line; Cell Survival; Dose-Response Relationship, | 2008 |
A fish hepatoma cell line (PLHC-1) as a tool to study cytotoxicity and CYP1A induction properties of cellulose and wood chip extracts.
Topics: Animals; Cell Line; Cell Survival; Cellulose; Chromatography, High Pressure Liquid; Cytochrome P-450 | 1998 |
Spontaneous hepatomas in mice inbred from Ha:ICR Swiss stock: effects of sex, cedar shavings in bedding, and immunization with fetal liver or hepatoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Female; Fetus; Liver; Liver Neoplasms, Experimental; Male; Mi | 1978 |
Enzyme-inducing and cytotoxic effects of wood-based materials used as bedding for laboratory animals. Comparison by a cell culture study.
Topics: Animal Husbandry; Animals; Animals, Laboratory; Cell Line; Cell Survival; Liver Neoplasms, Experimen | 1989 |