Page last updated: 2024-10-19

methanol and Encephalopathy, Toxic

methanol has been researched along with Encephalopathy, Toxic in 23 studies

Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.

Research Excerpts

ExcerptRelevanceReference
"To describe an unusual case of methanol-induced optic neuritis with bilateral multifocal extrafoveal serous retinal pigment epithelial (RPE) detachment."7.80An unusual case of bilateral multifocal retinal pigment epithelial detachment with methanol-induced optic neuritis. ( Gupta, RC; Khan, P; Kushwaha, R; Ranjan, R, 2014)
"In the longitudinal perspective, methanol poisoning survivors manifest progressive global cognitive decline and overall persistent below-average cognitive performance with some improvements in the frequency of depressive symptoms."4.02Cognitive changes after methanol exposure: Longitudinal perspective. ( Bezdicek, O; Brožová, H; Bukacova, K; Klempíř, J; Lišková, I; Mana, J; Pelclová, D; Poláková, K; Růžička, E; Žák, I; Zakharov, S, 2021)
"To describe an unusual case of methanol-induced optic neuritis with bilateral multifocal extrafoveal serous retinal pigment epithelial (RPE) detachment."3.80An unusual case of bilateral multifocal retinal pigment epithelial detachment with methanol-induced optic neuritis. ( Gupta, RC; Khan, P; Kushwaha, R; Ranjan, R, 2014)
" A young alcohol abuser was referred to the Acute Poisonings Unit at Wrocław with a presumptive diagnosis of methanol poisoning."3.73Poisoning or primary nervous system disease?--difficulties of the differential diagnosis exemplified by four different clinical cases. ( Antończyk, A; Kochman, K; Magdalan, J; Porebska, B, 2005)
"Methanol is a widely available chemical with a range of uses including as solvent, as a fuel, in chemical synthesis and anti-freeze preparations."1.56Methanol related death in National Institute of Forensic Medicine, Hospital Kuala Lumpur: A case series. ( Chng, KL; Lai, PS; Mahmood, MS; Md Yaro, SW; Siew, SF, 2020)
"Transient focal cerebral ischemia was induced by 2h middle cerebral artery occlusion followed by 24h reperfusion (MCAO/reperfusion) in rats."1.38Neuroprotection of the leaf and stem of Vitis amurensis and their active compounds against ischemic brain damage in rats and excitotoxicity in cultured neurons. ( Bae, K; Hwang, BY; Jeong, HY; Kim, JY; Kim, S; Lee, HK; Seong, YH, 2012)
"Methanol poisoning is an uncommon but potent central nervous system toxin."1.34Methanol poisoning: acute MR and CT findings in nine patients. ( Abbasi, HR; Borhani Haghighi, A; Kamali, K; Meshksar, A; Moghadami, M; Nabavizadeh, SA; Rasekhi, AR; Salooti, A; Sefidbakht, S, 2007)
" A dose-response was examined with each of these solvents."1.32The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity. ( Banasik, M; Persad, AS; Stedeford, T; Strosznajder, RP; Tanaka, S; Ueda, K, 2004)
"In Case 1, putamen hemorrhages were striking; white matter pathology predominated in Case 2."1.31August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter. ( Anthony, DC; De Girolami, U; Feany, MB; Frosch, MP; Zane, W, 2001)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (43.48)29.6817
2010's10 (43.48)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Shadfar, S1
Khanal, S1
Bohara, G1
Kim, G1
Sadigh-Eteghad, S1
Ghavami, S1
Choi, H1
Choi, DY1
Scully, RR1
Garcia, H1
McCoy, JT1
Ryder, VE1
Chng, KL1
Lai, PS1
Siew, SF1
Md Yaro, SW1
Mahmood, MS1
Bukacova, K1
Mana, J1
Klempíř, J1
Lišková, I1
Brožová, H1
Poláková, K1
Žák, I1
Pelclová, D1
Zakharov, S2
Růžička, E1
Bezdicek, O1
Doé de Maindreville, A1
Bakchine, S1
Papathanassiou, D1
Orquevaux, P1
Tranchant, C1
Roze, E1
Hlusicka, J1
Nurieva, O1
Kotikova, K1
Lischkova, L1
Kacer, P1
Kacerova, T1
Urban, P1
Vaneckova, M1
Seidl, Z1
Diblik, P1
Kuthan, P1
Heissigerova, J1
Lesovsky, J1
Rulisek, J1
Vojtova, L1
Hubacek, JA1
Navratil, T1
Khalaf, AA1
Galal, MK1
Ibrahim, MA1
Allah, AAA1
Afify, MM1
Refaat, R1
Singh, P1
Paliwal, VK1
Neyaz, Z1
Kanaujia, V1
Ranjan, R1
Kushwaha, R1
Gupta, RC1
Khan, P1
Algahtani, H1
Shirah, B1
Ahmad, R1
Abobaker, H1
Hmoud, M1
Paasma, R1
Hovda, KE1
Jacobsen, D1
Abrishami, M2
Khalifeh, M1
Shoayb, M1
Kim, JY1
Jeong, HY1
Lee, HK1
Kim, S1
Hwang, BY1
Bae, K1
Seong, YH1
Sanaei-Zadeh, H1
Dietemann, JL1
Botelho, C1
Nogueira, T1
Vargas, MI1
Audibert, C1
Abu Eid, M1
Bogorin, A1
Bernardo, R1
Jacques, C1
Kremer, S1
Zöllner, G1
Banasik, M1
Stedeford, T1
Strosznajder, RP1
Persad, AS1
Tanaka, S1
Ueda, K1
Magdalan, J1
Antończyk, A1
Kochman, K1
Porebska, B1
Blanco, M1
Casado, R1
Vázquez, F1
Pumar, JM1
Salzman, M1
Hantson, P1
Duprez, T1
Sandhir, R1
Kaur, K1
Sefidbakht, S1
Rasekhi, AR1
Kamali, K1
Borhani Haghighi, A1
Salooti, A1
Meshksar, A1
Abbasi, HR1
Moghadami, M1
Nabavizadeh, SA1
Feany, MB1
Anthony, DC1
Frosch, MP1
Zane, W1
De Girolami, U1

Reviews

4 reviews available for methanol and Encephalopathy, Toxic

ArticleYear
Revisions to Limits for Methanol in the Air of Spacecraft.
    Aerospace medicine and human performance, 2019, Sep-01, Volume: 90, Issue:9

    Topics: Animals; Astronauts; Cognition; Disease Models, Animal; Haplorhini; Humans; Incidence; Maximum Allow

2019
Transverse myelitis-like presentation of methanol intoxication: A case report and review of the literature.
    The journal of spinal cord medicine, 2018, Volume: 41, Issue:1

    Topics: Adult; Brain; Diagnosis, Differential; Humans; Male; Methanol; Myelitis, Transverse; Neurotoxicity S

2018
[Imaging in acute toxic encephalopathy].
    Journal of neuroradiology = Journal de neuroradiologie, 2004, Volume: 31, Issue:4

    Topics: Acute Disease; Alcohol Deterrents; Anticonvulsants; Carbon Monoxide Poisoning; Diagnosis, Differenti

2004
The value of morphological neuroimaging after acute exposure to toxic substances.
    Toxicological reviews, 2006, Volume: 25, Issue:2

    Topics: Acute Disease; Adult; Brain; Carbon Monoxide Poisoning; Cyanides; Humans; Magnetic Resonance Imaging

2006

Trials

1 trial available for methanol and Encephalopathy, Toxic

ArticleYear
Therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:3

    Topics: Administration, Oral; Adult; Alcoholic Beverages; Emergency Medical Services; Food Contamination; Fu

2011

Other Studies

18 other studies available for methanol and Encephalopathy, Toxic

ArticleYear
Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity.
    Molecular neurobiology, 2022, Volume: 59, Issue:9

    Topics: alpha-Synuclein; AMP-Activated Protein Kinases; Animals; Boswellia; Dopamine; Dopaminergic Neurons;

2022
Methanol related death in National Institute of Forensic Medicine, Hospital Kuala Lumpur: A case series.
    The Malaysian journal of pathology, 2020, Volume: 42, Issue:1

    Topics: Adult; Female; Humans; Malaysia; Male; Methanol; Middle Aged; Neurotoxicity Syndromes

2020
Cognitive changes after methanol exposure: Longitudinal perspective.
    Toxicology letters, 2021, Oct-01, Volume: 349

    Topics: Adult; Aged; Cognition; Cognitive Dysfunction; Czech Republic; Depression; Female; Humans; Longitudi

2021
Evidence of presynaptic dopaminergic dysfunction in acute methanol intoxication.
    Revue neurologique, 2017, Volume: 173, Issue:6

    Topics: Adult; Blindness; Coma; Dopamine; Dopaminergic Neurons; Glasgow Coma Scale; Humans; Magnetic Resonan

2017
Neuroinflammation markers and methyl alcohol induced toxic brain damage.
    Toxicology letters, 2018, Dec-01, Volume: 298

    Topics: Biomarkers; Brain; Cytokines; Evoked Potentials, Visual; Female; Humans; Inflammation Mediators; Mag

2018
The
    Bioscience reports, 2019, 03-29, Volume: 39, Issue:3

    Topics: Animals; Caspase 3; Catalase; Glutathione; Insecticides; Male; Malondialdehyde; Methanol; Neuroprote

2019
Methanol toxicity presenting as haemorrhagic putaminal necrosis and optic atrophy.
    Practical neurology, 2013, Volume: 13, Issue:3

    Topics: Adult; Humans; Intracranial Hemorrhages; Magnetic Resonance Imaging; Male; Methanol; Necrosis; Neuro

2013
An unusual case of bilateral multifocal retinal pigment epithelial detachment with methanol-induced optic neuritis.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2014, Volume: 10, Issue:1

    Topics: Adult; Alcohol Drinking; Alcoholism; Blindness; Dangerous Behavior; Food Contamination; Humans; Infu

2014
Methanol poisoning and long term sequelae - a six years follow-up after a large methanol outbreak.
    BMC clinical pharmacology, 2009, Mar-27, Volume: 9

    Topics: Alcoholic Intoxication; Disease Outbreaks; Estonia; Female; Follow-Up Studies; Humans; Male; Methano

2009
Neuroprotection of the leaf and stem of Vitis amurensis and their active compounds against ischemic brain damage in rats and excitotoxicity in cultured neurons.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Edema; Brain Injuries; Brain Ische

2012
What are the therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy?
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Emergency Medical Services; Glucocorticoids; Humans; Male; Methanol; Methylprednisolone; Neuroprotec

2012
The effects of organic solvents on poly(ADP-ribose) polymerase-1 activity: implications for neurotoxicity.
    Acta neurobiologiae experimentalis, 2004, Volume: 64, Issue:4

    Topics: Animals; Carbon Isotopes; Cattle; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ethanol; Inh

2004
Poisoning or primary nervous system disease?--difficulties of the differential diagnosis exemplified by four different clinical cases.
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Amphetamine; Antipsychotic Agents; Central Nervous System Stimulan

2005
CT and MR imaging findings in methanol intoxication.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:2

    Topics: Acidosis; Atrophy; Brain Edema; Coma; Critical Care; Diagnosis, Differential; Follow-Up Studies; Gla

2006
Methanol neurotoxicity.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:1

    Topics: Brain Infarction; Humans; Male; Methanol; Middle Aged; Neurotoxicity Syndromes; Poisoning; Putamen;

2006
Influence of ethanol on methanol-induced oxidative stress and neurobehavioral deficits.
    Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:5

    Topics: Acetylcholinesterase; Animals; Antioxidants; Behavior, Animal; Brain; Catalase; Ethanol; Glutathione

2006
Methanol poisoning: acute MR and CT findings in nine patients.
    Neuroradiology, 2007, Volume: 49, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Basal Ganglia; Basal Ganglia Diseases; Brain; Cerebral Hemorrhage; Dom

2007
August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter.
    Brain pathology (Zurich, Switzerland), 2001, Volume: 11, Issue:1

    Topics: Adult; Cerebral Hemorrhage; Fatal Outcome; Female; Humans; Methanol; Middle Aged; Necrosis; Neurotox

2001