Page last updated: 2024-10-19

methanol and Cranial Nerve II Diseases

methanol has been researched along with Cranial Nerve II Diseases in 45 studies

Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.

Research Excerpts

ExcerptRelevanceReference
"A 34-years-old floor-layer developed optic neuropathy and motor neuron disease after being accidentally exposed to a solvent mixture containing methanol and other substances."7.72Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture. ( Chiò, A; Discalzi, G; Herrero Hernandez, E; Mora, G; Pira, E; Valentini, C, 2004)
"To present results of electrophysiologic investigations of the visual toxicity observed during the early stage of methanol poisoning."7.70Evoked potentials investigation of visual dysfunction after methanol poisoning. ( Beguin, C; Boschi, A; de Tourtchaninoff, M; Guérit, JM; Hantson, P; Mahieu, P; Simoens, G, 1999)
"Methanol was isolated from a sample of the beverage with gas chromatography."5.37Methanol poisoning: two case studies of blindness in Indonesia. ( Bron, AM; Creuzot-Garcher, C; Koehrer, P, 2011)
"A 34-years-old floor-layer developed optic neuropathy and motor neuron disease after being accidentally exposed to a solvent mixture containing methanol and other substances."3.72Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture. ( Chiò, A; Discalzi, G; Herrero Hernandez, E; Mora, G; Pira, E; Valentini, C, 2004)
"We report a case of methanol blindness."3.71[Bilateral optic neuropathy in acute methanol intoxication. A case report]. ( Blain, P; Gaudric, A; Krivosic, V; Vignal-Clermont, C, 2001)
"To present results of electrophysiologic investigations of the visual toxicity observed during the early stage of methanol poisoning."3.70Evoked potentials investigation of visual dysfunction after methanol poisoning. ( Beguin, C; Boschi, A; de Tourtchaninoff, M; Guérit, JM; Hantson, P; Mahieu, P; Simoens, G, 1999)
"The authors report four cases of methanol poisoning, two of which suffering acute bilateral optic neuropathy which secondarily leads to optic atrophy."3.66[Optic neuropathy in acute poisoning with methanol]. ( Arne, JL; Bec, P; Bensouda, J; Dupeyron, G; Maillard, P; Sekkat, A, 1982)
"Methanol is an important public health and environmental concern because of the selective actions of its neurotoxic metabolite, formic acid, on the retina, optic nerve and central nervous system."2.41Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity. ( Eells, JT; Henry, MM; Lewandowski, MF; Murray, TG; Seme, MT, 2000)
"Methanol poisoning can cause an optic neuropathy that is usually severe and irreversible and often occurs after ingestion of illicit or homemade alcoholic beverages."1.48Erythropoietin in Treatment of Methanol Optic Neuropathy. ( Haghighi, A; Kashkouli, MB; Naderi, A; Pakdel, F; Pirmarzdashti, N; Sanjari, MS, 2018)
"Methanol poisoning has become very uncommon in Australasia with regulations that have reduced its retail availability."1.38Toxic cocktail: methanol poisoning in a tourist to Indonesia. ( Gee, P; Martin, E, 2012)
"Methanol was isolated from a sample of the beverage with gas chromatography."1.37Methanol poisoning: two case studies of blindness in Indonesia. ( Bron, AM; Creuzot-Garcher, C; Koehrer, P, 2011)
"Methanol is a highly toxic substance which is used as an industrial solvent and in automotive antifreeze."1.28Partly reversible visual failure with methanol toxicity. ( O'Day, J; Stelmach, MZ, 1992)
"The difficulties of identifying wooden foreign bodies as well as the topographical problems involved with the approach to the superior orbital fissure are discussed."1.28A wooden foreign body penetrating the superior orbital fissure. ( Hassler, W; Petersen, D; Zentner, J, 1991)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199010 (22.22)18.7374
1990's5 (11.11)18.2507
2000's8 (17.78)29.6817
2010's17 (37.78)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Liberski, S1
Kaluzny, BJ1
Kocięcki, J1
Baj, J1
Forma, A1
Kobak, J1
Tyczyńska, M1
Dudek, I1
Maani, A1
Teresiński, G1
Buszewicz, G1
Januszewski, J1
Flieger, J1
Jafarizadeh, A1
Homaie, M1
Abdollahi, M1
Niyousha, M1
Chraibi, F1
Moutei, H1
Bennis, A1
Abdellaoui, M1
Andaloussi Benatiya, I1
Khalili, MR1
Sadati, MS1
Jahanbani-Ardakani, H1
Zamani, N1
Hassanian-Moghaddam, H1
Shojaei, M1
Rahimian, S1
Pakdel, F1
Sanjari, MS1
Naderi, A1
Pirmarzdashti, N1
Haghighi, A1
Kashkouli, MB1
Nurieva, O3
Diblik, P3
Kuthan, P3
Sklenka, P3
Meliska, M3
Bydzovsky, J3
Heissigerova, J3
Urban, P3
Kotikova, K3
Navratil, T3
Komarc, M3
Seidl, Z3
Vaneckova, M3
Pelclova, D2
Zakharov, S3
Grzybowski, A2
Kanclerz, P1
Hubacek, JA1
Hlusicka, J1
Vojtova, L1
Bron, A1
Koehrer, P2
Creuzot-Garcher, C2
Sanaei-Zadeh, H2
Tanrivermis Sayit, A1
Aslan, K1
Elmali, M1
Gungor, I1
Pakravan, M2
Esfandiari, H1
Sanjari, N2
Ghahari, E1
Adinoff, B1
Wasinska-Borowiec, W1
Aghdam, KA1
Saari, JM1
Bhatia, R1
Kumar, M1
Garg, A1
Nanda, A1
Abrishami, M2
Khalifeh, M1
Shoayb, M1
Bron, AM1
Gee, P1
Martin, E1
BENTON, CD1
CALHOUN, EP1
BURK, M1
LASCO, F1
Chiò, A1
Herrero Hernandez, E1
Mora, G1
Valentini, C1
Discalzi, G1
Pira, E1
Nagasawa, H1
Wada, M1
Koyama, S1
Kawanami, T1
Kurita, K1
Kato, T1
Winnik, L1
Radomska, M1
Woś, M1
Pach, D1
Tachfouti, S1
Boutimzine, N1
Cherkaoui, O1
Mohcine, Z1
Sharpe, JA1
Hostovsky, M1
Bilbao, JM1
Rewcastle, NB1
Sekkat, A1
Maillard, P1
Dupeyron, G1
Bensouda, J1
Arne, JL1
Bec, P1
Sullivan-Mee, M1
Solis, K1
Sharma, M1
Volpe, NJ1
Dreyer, EB1
Hantson, P1
de Tourtchaninoff, M1
Simoens, G1
Mahieu, P1
Boschi, A1
Beguin, C1
Guérit, JM1
Eells, JT1
Henry, MM1
Lewandowski, MF1
Seme, MT1
Murray, TG1
Krivosic, V1
Vignal-Clermont, C1
Blain, P1
Gaudric, A1
Sodhi, PK1
Goyal, JL1
Mehta, DK1
Dethlefs, R1
Naraqi, S1
Stelmach, MZ1
O'Day, J1
Hayreh, SS1
Naeser, P1
Ogawa, Y1
Takatsuki, R1
Uema, T1
Seki, Y1
Hiramatsu, K1
Okayama, A1
Morimoto, K1
Kaneko, Z1
Indeĭkin, EN1
Zentner, J1
Hassler, W1
Petersen, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.[NCT05748561]Phase 2/Phase 318 participants (Anticipated)Interventional2022-04-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for methanol and Cranial Nerve II Diseases

ArticleYear
Methanol-induced optic neuropathy: a still-present problem.
    Archives of toxicology, 2022, Volume: 96, Issue:2

    Topics: Animals; Axons; Formates; Humans; Methanol; Mitochondria; Optic Nerve; Optic Nerve Diseases; Oxidati

2022
Toxic and Nutritional Optic Neuropathies-An Updated Mini-Review.
    International journal of environmental research and public health, 2022, 03-06, Volume: 19, Issue:5

    Topics: Humans; Malnutrition; Methanol; Optic Nerve; Optic Nerve Diseases; Vision Disorders

2022
An Updated Review on the Most Common Agents Causing Toxic Optic Neuropathies.
    Current pharmaceutical design, 2017, Volume: 23, Issue:4

    Topics: Amiodarone; Erythropoietin; Ethambutol; Humans; Linezolid; Methanol; Optic Nerve Diseases; Phosphodi

2017
Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity.
    Neurotoxicology, 2000, Volume: 21, Issue:3

    Topics: Animals; Disease Models, Animal; Folic Acid; Formates; Humans; Methanol; Optic Nerve; Optic Nerve Di

2000

Trials

2 trials available for methanol and Cranial Nerve II Diseases

ArticleYear
Erythropoietin as an adjunctive treatment for methanol-induced toxic optic neuropathy.
    The American journal of drug and alcohol abuse, 2016, Volume: 42, Issue:6

    Topics: Administration, Intravenous; Adult; Drug Therapy, Combination; Erythropoietin; Follow-Up Studies; Gl

2016
Therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:3

    Topics: Administration, Oral; Adult; Alcoholic Beverages; Emergency Medical Services; Food Contamination; Fu

2011

Other Studies

39 other studies available for methanol and Cranial Nerve II Diseases

ArticleYear
Time course study of optical coherence tomography angiography in patients with methanol induced optic neuropathy.
    BMC ophthalmology, 2023, Apr-25, Volume: 23, Issue:1

    Topics: Angiography; Case-Control Studies; Fluorescein Angiography; Humans; Methanol; Optic Nerve Diseases;

2023
Methanol-induced optic neuropathy.
    Journal francais d'ophtalmologie, 2020, Volume: 43, Issue:9

    Topics: Humans; Methanol; Optic Nerve; Optic Nerve Diseases

2020
Outbreak of methanol-induced optic neuropathy amid COVID-19 pandemic.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021, Volume: 259, Issue:5

    Topics: COVID-19; Disease Outbreaks; Humans; Iran; Methanol; Optic Nerve Diseases; SARS-CoV-2; Self Medicati

2021
Evaluation of the effect of erythropoietin + corticosteroid versus corticosteroid alone in methanol-induced optic nerve neuropathy.
    Cutaneous and ocular toxicology, 2018, Volume: 37, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Erythropoietin; Humans; Metha

2018
Erythropoietin in Treatment of Methanol Optic Neuropathy.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2018, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Erythropoietin; Female; Humans; Infusions, Intravenous; Male; Methanol; Middle Ag

2018
Progressive Chronic Retinal Axonal Loss Following Acute Methanol-induced Optic Neuropathy: Four-Year Prospective Cohort Study.
    American journal of ophthalmology, 2018, Volume: 191

    Topics: Acute Disease; Axons; Brain; Chronic Disease; Disease Progression; Female; Follow-Up Studies; Humans

2018
Reply.
    American journal of ophthalmology, 2018, Volume: 195

    Topics: Humans; Methanol; Optic Nerve Diseases; Optic Neuritis; Prospective Studies

2018
Progressive Chronic Retinal Axonal Loss Following Acute Methanol-Induced Optic Neuropathy: Four-Year Prospective Cohort Study.
    American journal of ophthalmology, 2018, Volume: 195

    Topics: Humans; Methanol; Optic Nerve Diseases; Optic Neuritis; Prospective Studies; Retina

2018
Clinical and genetic determinants of chronic visual pathway changes after methanol - induced optic neuropathy: four-year follow-up study.
    Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:6

    Topics: Adult; Apolipoprotein E4; Case-Control Studies; Czech Republic; Evoked Potentials, Visual; Female; F

2019
Response of the authors.
    International ophthalmology, 2014, Volume: 34, Issue:3

    Topics: Blindness; Humans; Male; Methanol; Optic Nerve Diseases

2014
Optical coherence tomography of the macula and optic nerve in methanol-intoxicated patients and the effect of intravenous corticosteroids on their visual disturbances.
    International ophthalmology, 2014, Volume: 34, Issue:3

    Topics: Blindness; Humans; Male; Methanol; Optic Nerve Diseases

2014
Methanol-induced toxic optic neuropathy with diffusion weighted MRI findings.
    Cutaneous and ocular toxicology, 2016, Volume: 35, Issue:4

    Topics: Diffusion Magnetic Resonance Imaging; Humans; Male; Methanol; Middle Aged; Optic Nerve Diseases; Per

2016
The costs of prohibition.
    The American journal of drug and alcohol abuse, 2016, Volume: 42, Issue:6

    Topics: Erythropoietin; Humans; Methanol; Optic Nerve Diseases

2016
Putaminal necrosis due to methanol toxicity.
    Practical neurology, 2008, Volume: 8, Issue:6

    Topics: Adult; Basal Ganglia Diseases; Blindness; Disease Progression; Humans; Magnetic Resonance Imaging; M

2008
Methanol poisoning: two case studies of blindness in Indonesia.
    International ophthalmology, 2011, Volume: 31, Issue:6

    Topics: Adult; Blindness; Humans; Indonesia; Male; Methanol; Middle Aged; Optic Nerve Diseases

2011
What are the therapeutic effects of high-dose intravenous prednisolone in methanol-induced toxic optic neuropathy?
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Emergency Medical Services; Glucocorticoids; Humans; Male; Methanol; Methylprednisolone; Neuroprotec

2012
Erythropoietin treatment for methanol optic neuropathy.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2012, Volume: 32, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Adult; Anti-Inflammatory Agents; Erythropoietin;

2012
Toxic cocktail: methanol poisoning in a tourist to Indonesia.
    Emergency medicine Australasia : EMA, 2012, Volume: 24, Issue:4

    Topics: Alcoholic Beverages; Female; Humans; Indonesia; Methanol; Optic Nerve Diseases; Travel; Vision Disor

2012
The ocular effects of methyl alcohol poisoning; report of a catastrophe involving 320 persons.
    American journal of ophthalmology, 1953, Volume: 36, Issue:12

    Topics: Blindness; Disease; Edema; Eye; Humans; Methanol; Optic Nerve; Optic Nerve Diseases; Retina; Retinal

1953
[Chronic industrial methyl alcohol poisoning].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1957, Volume: 130, Issue:6

    Topics: Alcoholism; Disease; Ethanol; Eye; Humans; Methanol; Optic Nerve; Optic Nerve Diseases

1957
[Pseudoglaucoma after poisoning by methyl alcohol].
    Annales d'oculistique, 1958, Volume: 191, Issue:3

    Topics: Disease; Ethanol; Eye; Eye Diseases, Hereditary; Humans; Methanol; Optic Nerve; Optic Nerve Diseases

1958
Motor neuron disease and optic neuropathy after acute exposure to a methanol-containing solvent mixture.
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2004, Volume: 5, Issue:3

    Topics: Adult; Brain Mapping; Humans; Magnetic Resonance Imaging; Male; Methanol; Motor Neuron Disease; Opti

2004
[A case of methanol intoxication with optic neuropathy visualized on STIR sequence of MR images].
    Rinsho shinkeigaku = Clinical neurology, 2005, Volume: 45, Issue:7

    Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Methanol; Optic Nerve Diseases

2005
[The CNS damage due to methanol poisoning in the case of 23-year-old male patient addicted to organic solvents].
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Acidosis; Adult; Blindness; Humans; Inhalation; Male; Methanol; Optic Nerve Diseases; Solvents; Subs

2005
[Bilateral optic neuropathy from methanol intoxication. A case report].
    Bulletin de la Societe belge d'ophtalmologie, 2005, Issue:297

    Topics: Adrenal Cortex Hormones; Adult; Humans; Male; Methanol; Optic Nerve Diseases; Treatment Failure; Vit

2005
Methanol optic neuropathy: a histopathological study.
    Neurology, 1982, Volume: 32, Issue:10

    Topics: Brain Diseases; Cerebral Cortex; Formates; Humans; Male; Methanol; Middle Aged; Myelin Sheath; Optic

1982
[Optic neuropathy in acute poisoning with methanol].
    Journal francais d'ophtalmologie, 1982, Volume: 5, Issue:12

    Topics: Adult; Amblyopia; Fluorescein Angiography; Humans; Male; Methanol; Optic Atrophy; Optic Nerve Diseas

1982
Methanol-induced vision loss.
    Journal of the American Optometric Association, 1998, Volume: 69, Issue:1

    Topics: Acidosis; Adult; Follow-Up Studies; Fundus Oculi; Humans; Male; Methanol; Optic Nerve Diseases; Pupi

1998
Methanol-induced optic nerve cupping.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:2

    Topics: Adult; Blindness; Humans; Male; Methanol; Optic Disk; Optic Nerve Diseases

1999
Evoked potentials investigation of visual dysfunction after methanol poisoning.
    Critical care medicine, 1999, Volume: 27, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Electrophysiology; Ethanol; Evoked Potentials, Visual; Femal

1999
[Bilateral optic neuropathy in acute methanol intoxication. A case report].
    Journal francais d'ophtalmologie, 2001, Volume: 24, Issue:5

    Topics: Alcoholic Intoxication; Anti-Inflammatory Agents; Antidotes; Blindness; Hemodiafiltration; Humans; M

2001
Methanol-induced optic neuropathy: treatment with intravenous high dose steroids.
    International journal of clinical practice, 2001, Volume: 55, Issue:9

    Topics: Adult; Drug Administration Schedule; Glucocorticoids; Humans; Injections, Intravenous; Male; Methano

2001
Ocular manifestations and complications of acute methyl alcohol intoxication.
    The Medical journal of Australia, 1978, Nov-04, Volume: 2, Issue:10

    Topics: Adaptation, Ocular; Blindness; Eye Diseases; Follow-Up Studies; Humans; Male; Methanol; Optic Nerve

1978
Partly reversible visual failure with methanol toxicity.
    Australian and New Zealand journal of ophthalmology, 1992, Volume: 20, Issue:1

    Topics: Adolescent; Female; Fluorescein Angiography; Fundus Oculi; Humans; Methanol; Optic Atrophy; Optic Ne

1992
Optic nerve involvement in methanol poisoning.
    The British journal of ophthalmology, 1989, Volume: 73, Issue:3

    Topics: Animals; Humans; Macaca mulatta; Methanol; Optic Nerve Diseases

1989
Optic nerve involvement in a case of methanol poisoning.
    The British journal of ophthalmology, 1988, Volume: 72, Issue:10

    Topics: Adult; Humans; Male; Methanol; Necrosis; Optic Nerve; Optic Nerve Diseases

1988
Acute optic neuropathy induced by thinner sniffing: inhalation of mixed organic solvent containing methyl alcohol and methyl acetate.
    Industrial health, 1988, Volume: 26, Issue:4

    Topics: Acetates; Adult; Humans; Male; Methanol; Optic Nerve Diseases; Solvents; Substance-Related Disorders

1988
[Alcohol and vision].
    Fel'dsher i akusherka, 1986, Volume: 51, Issue:10

    Topics: Adult; Alcoholism; Ethanol; Humans; Male; Methanol; Optic Nerve Diseases; Smoking; Vision Disorders;

1986
A wooden foreign body penetrating the superior orbital fissure.
    Neurochirurgia, 1991, Volume: 34, Issue:6

    Topics: Bicycling; Child; Diagnosis, Differential; Escherichia coli Infections; Eye Foreign Bodies; Eye Inju

1991