Page last updated: 2024-10-19

methanol and Colonic Neoplasms

methanol has been researched along with Colonic Neoplasms in 39 studies

Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"The present study investigated the protective effect of methanolic extract from Fuzhuan brick‑tea (FME) on hydrogen peroxide (H2O2)‑induced oxidative stress in the human intestinal epithelial adenocarcinoma cell line Caco‑2."7.80Effects of methanolic extract form Fuzhuan brick-tea on hydrogen peroxide-induced oxidative stress in human intestinal epithelial adenocarcinoma Caco-2 cells. ( Gao, Y; Song, JL, 2014)
"Colon carcinogenesis was initiated in Wistar rats by intraperitoneal injections of azoxymethane (AOM), once a week for two weeks."5.39Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model. ( Barth, SW; Bousserouel, S; Gossé, F; Le Grandois, J; Marchioni, E; Marescaux, J; Raul, F; Werner, D, 2013)
"The present study investigated the protective effect of methanolic extract from Fuzhuan brick‑tea (FME) on hydrogen peroxide (H2O2)‑induced oxidative stress in the human intestinal epithelial adenocarcinoma cell line Caco‑2."3.80Effects of methanolic extract form Fuzhuan brick-tea on hydrogen peroxide-induced oxidative stress in human intestinal epithelial adenocarcinoma Caco-2 cells. ( Gao, Y; Song, JL, 2014)
"serrata) on HT-29 human colon cancer cells."1.46Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. ( Moradkhani, S; Najafi, R; Ranjbarnejad, T; Saidijam, M, 2017)
"Dimethyl fumarate (DMF) is a newly approved drug for the treatment of relapsing forms of multiple sclerosis and relapsing-remitting multiple sclerosis."1.42Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway. ( Dong, DL; Gao, JL; Jin, J; Li, N; Ma, CY; Shen, X; Sun, ZJ; Wang, CG; Xie, X; Xu, XM; Zhang, YQ; Zhao, Y, 2015)
"Colon carcinogenesis was initiated in Wistar rats by intraperitoneal injections of azoxymethane (AOM), once a week for two weeks."1.39Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model. ( Barth, SW; Bousserouel, S; Gossé, F; Le Grandois, J; Marchioni, E; Marescaux, J; Raul, F; Werner, D, 2013)
"The methanol skin extract was dried under reduced pressure, giving a 5."1.38Investigation of the cytocidal potential of Rhinella jimi skin methanol extracts. ( Almeida, WO; Angélico, EC; Anjos, LA; Brito, SV; Carvalho, JE; Costa, JG; Coutinho, HD; Ferreira, FS; Rodrigues, FF; Sales, DL, 2012)
"Significantly increased risk of colon cancer was seen in the cohort (SIR 1."1.31Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia. ( Innos, K; Lang, I; Leon, DA; Rahu, K; Rahu, M, 2000)
"When HCT-15 cells, derived from human colon cancer or AGS cells, derived from human gastric cancer, were cultured with these fractions, the anthocyanin fraction from the red wine and the non-anthocyanic substances extracted from red and white wines suppressed the growth of the cells, and the suppression rate by the anthocyanin fraction was significantly higher than that of the other fractions."1.30Anti-tumor effect of methanol extracts from red and white wines. ( Hasegawa, M; Hashimoto, Y; Kamei, H; Koide, T; Kojima, T, 1998)
"While risk for rectal cancer did not seem to be limited to any particular type of dust or fume, the excess risk was strongest for wood and metal dusts."1.28A case-control study of occupational and dietary factors in colorectal cancer in young men by subsite. ( Garabrant, DH; Mack, TM; Peters, RK; Yu, MC, 1989)
"Nonsignificant excess proportions of cancer deaths occurred at a number of other anatomical sites."1.26Pattern and model makers, proportionate mortality 1972-1978. ( McCammon, CS; Robinson, C; Waxweiler, RJ, 1980)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19907 (17.95)18.7374
1990's6 (15.38)18.2507
2000's5 (12.82)29.6817
2010's18 (46.15)24.3611
2020's3 (7.69)2.80

Authors

AuthorsStudies
Silva, CD1
Ramalhete, C1
Spengler, G1
Mulhovo, S1
Molnar, J1
Ferreira, MU1
Jisha, N1
Vysakh, A1
Vijeesh, V1
Anand, PS1
Latha, MS1
Yuvali, G1
Onbasli, D1
Ranjbarnejad, T1
Saidijam, M1
Moradkhani, S1
Najafi, R1
Namvaran, A1
Fazeli, M1
Farajnia, S1
Hamidian, G1
Rezazadeh, H1
Md Nasir, NL1
Kamsani, NE1
Mohtarrudin, N1
Othman, F1
Md Tohid, SF1
Zakaria, ZA1
Bousserouel, S1
Le Grandois, J1
Gossé, F1
Werner, D1
Barth, SW1
Marchioni, E1
Marescaux, J1
Raul, F1
Song, JL1
Gao, Y1
Park, KW2
Kundu, J1
Chae, IG1
Bachar, SC1
Bae, JW1
Chun, KS1
Xie, X1
Zhao, Y1
Ma, CY1
Xu, XM1
Zhang, YQ1
Wang, CG1
Jin, J1
Shen, X1
Gao, JL1
Li, N1
Sun, ZJ1
Dong, DL1
Mathieson, W1
Marcon, N1
Antunes, L1
Ashford, DA1
Betsou, F1
Frasquilho, SG1
Kofanova, OA1
McKay, SC1
Pericleous, S1
Smith, C1
Unger, KM1
Zeller, C1
Thomas, GA1
Nasri, I1
Chawech, R1
Girardi, C1
Mas, E1
Ferrand, A1
Vergnolle, N1
Fabre, N1
Mezghani-Jarraya, R1
Racaud-Sultan, C1
Ren, MR1
Hur, JS1
Kim, JY2
Park, SC1
Seong, CN1
Jeong, IY1
Byun, MW1
Lee, MK1
Seo, KI1
Zeng, H3
Botnen, JH1
Briske-Anderson, M2
Simó, C2
Ibáñez, C2
Gómez-Martínez, A1
Ferragut, JA1
Cifuentes, A2
Sakandé, J1
Rouet-benzineb, P1
Devaud, H1
Nikiema, JB1
Lompo, M1
Nacoulma, OG1
Guissou, IP1
Bado, A1
Wu, M1
Moyer, MP1
Fiala, ES1
Ramasamy, S1
Abdul Wahab, N1
Zainal Abidin, N1
Manickam, S1
Zakaria, Z1
Celebier, M1
Brito, SV1
Sales, DL1
Costa, JG1
Rodrigues, FF1
Ferreira, FS1
Angélico, EC1
Carvalho, JE1
Almeida, WO1
Anjos, LA1
Coutinho, HD1
Cheng, WH1
Johnson, LK1
Konishi, T1
Satsu, H1
Hatsugai, Y1
Aizawa, K1
Inakuma, T1
Nagata, S1
Sakuda, SH1
Nagasawa, H1
Shimizu, M1
Hwang, JH1
Cha, MR1
Park, HR1
Lee, MY1
Lin, HY1
Cheng, F1
Chiang, W1
Kuo, YH1
Noguchi, M1
Furuya, S1
Takeuchi, T1
Hirohashi, S1
Wilson, GD1
Kamei, H1
Hashimoto, Y1
Koide, T1
Kojima, T1
Hasegawa, M1
Iozzo, RV1
Kovalszky, I1
Hacobian, N1
Schick, PK1
Ellingson, JS1
Dodge, GR1
Zedeck, MS1
Sternberg, SS1
Weisburger, JH1
Skalova, A1
Sar, A1
Laco, J1
Metelkova, A1
Miesbauerova, M1
Steiner, P1
Švajdler, M1
Michal, M1
Robinson, C1
Waxweiler, RJ1
McCammon, CS2
Demers, RY1
Innos, K1
Rahu, M1
Rahu, K1
Lang, I1
Leon, DA1
Roscoe, RJ1
Steenland, K1
Schober, SE1
Robinson, CF1
Halperin, WE1
Fingerhut, MA1
Peters, RK1
Garabrant, DH1
Yu, MC1
Mack, TM1
Swanson, GM1
Belle, SH1
Burrows, RW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2 Study of Orally Administrated JBM-TC4 for the Prevention of Acute Radiation-induced Dermatitis in Breast Cancer Patients[NCT02289365]Phase 2120 participants (Actual)Interventional2014-11-30Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methanol and Colonic Neoplasms

ArticleYear
Colon carcinogens: their metabolism and mode of action.
    Cancer, 1971, Volume: 28, Issue:1

    Topics: Animals; Bacteria; Bile Acids and Salts; Biochemical Phenomena; Biochemistry; Carcinogens; Colonic N

1971

Other Studies

38 other studies available for methanol and Colonic Neoplasms

ArticleYear
Triterpenes from Momordica balsamina (African pumpkin): ABCB1 inhibition and synergistic interaction with doxorubicin in resistant cancer cells.
    Phytochemistry, 2022, Volume: 203

    Topics: Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Colonic Ne

2022
Methanolic Extract of
    Nutrition and cancer, 2021, Volume: 73, Issue:11-12

    Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogenesis; Colon; Colonic Neoplasms; Methanol; Pl

2021
Cytotoxicity of
    International journal of environmental health research, 2022, Volume: 32, Issue:10

    Topics: Agaricales; Antioxidants; Ascomycota; Cell Line; Colonic Neoplasms; Flavonoids; Humans; Methanol; Ph

2022
Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells.
    Prostaglandins & other lipid mediators, 2017, Volume: 131

    Topics: Antineoplastic Agents; Apoptosis; Boswellia; Caspase 3; Cell Movement; Colonic Neoplasms; Gene Expre

2017
Apoptosis and Caspase 3 Pathway Role on Anti-Proliferative Effects of Scrophulariaoxy Sepala Methanolic Extract on Caco-2 Cells.
    Drug research, 2017, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Capecitabine; Caspase 3; Cisplatin; Colo

2017
Anticarcinogenic activity of Muntingia calabura leaves methanol extract against the azoxymethane-induced colon cancer in rats involved modulation of the colonic antioxidant system partly by flavonoids.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Azoxymethane; Colon; Colonic Neoplasms; El

2017
Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model.
    International journal of oncology, 2013, Volume: 43, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Asparagus Plant; Azoxymethane; Carcinogenesis; Caspase

2013
Effects of methanolic extract form Fuzhuan brick-tea on hydrogen peroxide-induced oxidative stress in human intestinal epithelial adenocarcinoma Caco-2 cells.
    Molecular medicine reports, 2014, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Caco-2 Cells; Camellia sinensis; Catalase; Cell Survival; Colonic Neoplasms; Glutath

2014
Methanol extract of Flacourtia indica aerial parts induces apoptosis via generation of ROS and activation of caspases in human colon cancer HCT116 cells.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:17

    Topics: Apoptosis; bcl-X Protein; Carcinoma; Caspase 3; Cell Proliferation; Cell Survival; Colonic Neoplasms

2014
Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway.
    British journal of pharmacology, 2015, Volume: 172, Issue:15

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dimethyl Fumarate; Fumarates

2015
A Critical Evaluation of the PAXgene Tissue Fixation System:  Morphology, Immunohistochemistry, Molecular Biology, and Proteomics.
    American journal of clinical pathology, 2016, Volume: 146, Issue:1

    Topics: Acetic Acid; Adult; Aged; Carcinoma; Colonic Neoplasms; Ethanol; Female; Gene Expression Profiling;

2016
Anti-inflammatory and anticancer effects of flavonol glycosides from Diplotaxis harra through GSK3β regulation in intestinal cells.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Brassicaceae; Caco-2 Cells; Cell Surviv

2017
Anti-proliferative effects of Lethariella zahlbruckneri extracts in human HT-29 human colon cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:9

    Topics: Acetone; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X

2009
Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells.
    Nutrition and cancer, 2010, Volume: 62, Issue:1

    Topics: Apoptosis; Cell Cycle; Colonic Neoplasms; Deoxycholic Acid; Enzyme Activation; G1 Phase; G2 Phase; H

2010
Is metabolomics reachable? Different purification strategies of human colon cancer cells provide different CE-MS metabolite profiles.
    Electrophoresis, 2011, Volume: 32, Issue:13

    Topics: Cell Extracts; Colonic Neoplasms; Electrophoresis, Capillary; HT29 Cells; Humans; Mass Spectrometry;

2011
Dichloromethane-methanol extract from Borassus aethiopumn mart. (Arecaceae) induces apoptosis of human colon cancer HT-29 cells.
    Pakistan journal of biological sciences : PJBS, 2011, May-15, Volume: 14, Issue:10

    Topics: Apoptosis; Arecaceae; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; HT29

2011
Methylselenol, a selenium metabolite, plays common and different roles in cancerous colon HCT116 cell and noncancerous NCM460 colon cell proliferation.
    Nutrition and cancer, 2012, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Colon; Colonic Neoplasm

2012
The formation of azoxymethane, a colon carcinogen, during the chemical oxidation of methylamine.
    Carcinogenesis, 1980, Volume: 1, Issue:1

    Topics: Azoxymethane; Carcinogens; Chromatography, High Pressure Liquid; Colonic Neoplasms; Gas Chromatograp

1980
Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Acetates; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Cell Shape; C

2012
A Foodomics approach: CE-MS for comparative metabolomics of colon cancer cells treated with dietary polyphenols.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 869

    Topics: Cell Extracts; Colonic Neoplasms; Electrophoresis, Capillary; Food; Fractional Precipitation; HT29 C

2012
Investigation of the cytocidal potential of Rhinella jimi skin methanol extracts.
    Pharmaceutical biology, 2012, Volume: 50, Issue:8

    Topics: Animals; Antineoplastic Agents; Brazil; Bufonidae; Cell Death; Cell Line, Tumor; Cell Proliferation;

2012
Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of colon cancer xenografts in Balb/c mice.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:5

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Depe

2013
Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: Adenocarcinoma; Amino Acids; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Ca

2004
Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells.
    Journal of medicinal food, 2007, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bombyx; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell D

2007
Isolation and characterization of new lactam compounds that inhibit lung and colon cancer cells from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) bran.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Coix; Colonic Neoplasms; HT29 Cells; Humans;

2008
Modified formalin and methanol fixation methods for molecular biological and morphological analyses.
    Pathology international, 1997, Volume: 47, Issue:10

    Topics: Breast; Breast Neoplasms; Colon; Colonic Neoplasms; DNA; Fixatives; Formaldehyde; Gastric Mucosa; Hu

1997
Flow cytometric detection of proliferation-associated antigens, PCNA and Ki-67.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 80

    Topics: Animals; Antibodies, Monoclonal; Cell Membrane Permeability; Colonic Neoplasms; Detergents; Fixative

1998
Anti-tumor effect of methanol extracts from red and white wines.
    Cancer biotherapy & radiopharmaceuticals, 1998, Volume: 13, Issue:6

    Topics: Anthocyanins; Antineoplastic Agents; Cell Cycle; Colonic Neoplasms; Flavonoids; Humans; Methanol; St

1998
Fatty acylation of heparan sulfate proteoglycan from human colon carcinoma cells.
    The Journal of biological chemistry, 1990, Nov-15, Volume: 265, Issue:32

    Topics: Acylation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cycloheximide; Electrophoresis,

1990
A model system for studies of colon carcinogenesis: tumor induction by a single injection of methylazoxymethanol acetate.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Animals; Azo Compounds; Carcinogens; Colonic Neoplasms; Male; Methanol; Neoplasms, E

1974
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
    Applied immunohistochemistry & molecular morphology : AIMM, 2018, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; CDX2 Transcription Factor; Colonic Neoplasms; Colorectal Ne

2018
Pattern and model makers, proportionate mortality 1972-1978.
    American journal of industrial medicine, 1980, Volume: 1, Issue:2

    Topics: Brain Neoplasms; Colonic Neoplasms; Death Certificates; Epidemiologic Methods; Humans; Male; Metals;

1980
Colon and stomach cancer mortality among automotive wood model makers.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1993, Volume: 35, Issue:4

    Topics: Bias; Cause of Death; Cohort Studies; Colonic Neoplasms; Death Certificates; Dust; Humans; Occupatio

1993
Wood dust exposure and cancer incidence: a retrospective cohort study of furniture workers in Estonia.
    American journal of industrial medicine, 2000, Volume: 37, Issue:5

    Topics: Adult; Cohort Studies; Colonic Neoplasms; Confidence Intervals; Dust; Employment; Estonia; Female; F

2000
Colon and stomach cancer mortality among automotive wood model makers.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1992, Volume: 34, Issue:8

    Topics: Automobiles; Case-Control Studies; Cohort Studies; Colonic Neoplasms; Humans; Male; Occupational Dis

1992
A case-control study of occupational and dietary factors in colorectal cancer in young men by subsite.
    Cancer research, 1989, Oct-01, Volume: 49, Issue:19

    Topics: Adenocarcinoma; Adult; Age Factors; Colonic Neoplasms; Dust; Feeding Behavior; Food Handling; Humans

1989
Occupational exposures to chlorophenols.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1986, Volume: 41

    Topics: Animals; Chlorophenols; Colonic Neoplasms; Environmental Exposure; Epidemiologic Methods; Female; Hu

1986
Colon cancer incidence among modelmakers and patternmakers in the automobile manufacturing industry. A continuing dilemma.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1985, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Automobiles; Colonic Neoplasms; Cross-Sectional Studies; Humans; Male; Mich

1985