methanol has been researched along with Alzheimer Disease in 22 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "in the treatment of Alzheimer's disease, but there is a lack of scientific data to support the efficacy and safety of Cannabis sativa L." | 1.72 | Cannabis Sativa L. Flower and Bud Extracts Inhibited In vitro Cholinesterases and β-Secretase Enzymes Activities: Possible Mechanisms of Cannabis Use in Alzheimer Disease. ( Bala, A; Chaudhary, SK; Kumar, CS; Mahadevappa, CP; Matsabisa, MG; Mooko, T; Tripathy, S, 2022) |
| " The method proved to be applicable to the pharmacokinetic study of B9M in rat after intravenous and subcutaneous administration." | 1.38 | Determination of Bis(9)-(-)-Meptazinol, a bis-ligand for Alzheimer's disease, in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetics study. ( Chen, HZ; Ge, XX; Jiang, P; Jiang, T; Qiu, ZB; Rong, ZX; Wang, H; Wang, XL; Xie, Q; Xie, Y; Zhang, QZ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 8 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Navarro-Hortal, MD | 1 |
| Romero-Márquez, JM | 1 |
| Esteban-Muñoz, A | 1 |
| Sánchez-González, C | 1 |
| Rivas-García, L | 1 |
| Llopis, J | 1 |
| Cianciosi, D | 1 |
| Giampieri, F | 1 |
| Sumalla-Cano, S | 1 |
| Battino, M | 1 |
| Quiles, JL | 1 |
| Lamrani, M | 1 |
| Serseg, T | 1 |
| Benarous, K | 1 |
| Sifi, I | 1 |
| Yousfi, M | 1 |
| Nakajima, K | 1 |
| Okubo, S | 1 |
| Oiso, S | 1 |
| Mahnashi, MH | 1 |
| Ashraf, M | 1 |
| Alhasaniah, AH | 1 |
| Ullah, H | 1 |
| Zeb, A | 1 |
| Ghufran, M | 1 |
| Fahad, S | 1 |
| Ayaz, M | 1 |
| Daglia, M | 1 |
| Ismail, H | 1 |
| Khalid, D | 1 |
| Waseem, D | 1 |
| Ijaz, MU | 1 |
| Dilshad, E | 1 |
| Haq, IU | 1 |
| Bhatti, MZ | 1 |
| Anwaar, S | 1 |
| Ahmed, M | 1 |
| Saleem, S | 1 |
| Abidar, S | 1 |
| Yildiz, O | 1 |
| Degirmenci, A | 1 |
| Amakran, A | 1 |
| El Maadoudi, M | 1 |
| Nhiri, M | 1 |
| Yano, M | 1 |
| Nakashima, S | 1 |
| Oda, Y | 1 |
| Nakamura, S | 1 |
| Matsuda, H | 1 |
| Afsharnezhad, M | 1 |
| Shahangian, SS | 1 |
| Rasti, B | 1 |
| Faezi Ghasemi, M | 1 |
| Mooko, T | 1 |
| Bala, A | 1 |
| Tripathy, S | 1 |
| Kumar, CS | 1 |
| Mahadevappa, CP | 1 |
| Chaudhary, SK | 1 |
| Matsabisa, MG | 1 |
| Postu, PA | 1 |
| Noumedem, JAK | 1 |
| Cioanca, O | 3 |
| Hancianu, M | 3 |
| Mihasan, M | 3 |
| Ciorpac, M | 1 |
| Gorgan, DL | 1 |
| Petre, BA | 1 |
| Hritcu, L | 3 |
| Abbas-Mohammadi, M | 1 |
| Moridi Farimani, M | 1 |
| Salehi, P | 1 |
| Nejad Ebrahimi, S | 1 |
| Sonboli, A | 1 |
| Kelso, C | 1 |
| Skropeta, D | 1 |
| Salissou, MTM | 1 |
| Mahaman, YAR | 1 |
| Zhu, F | 1 |
| Huang, F | 1 |
| Wang, Y | 1 |
| Xu, Z | 1 |
| Ke, D | 1 |
| Wang, Q | 1 |
| Liu, R | 1 |
| Wang, JZ | 1 |
| Zhang, B | 1 |
| Wang, X | 1 |
| Noumedem, JA | 2 |
| Kuete, V | 1 |
| Yang, M | 1 |
| Miao, J | 1 |
| Rizak, J | 1 |
| Zhai, R | 1 |
| Wang, Z | 1 |
| Huma, T | 1 |
| Li, T | 1 |
| Zheng, N | 1 |
| Wu, S | 1 |
| Zheng, Y | 1 |
| Fan, X | 1 |
| Yang, J | 1 |
| Wang, J | 1 |
| Yang, S | 1 |
| Ma, Y | 1 |
| Lü, L | 1 |
| He, R | 1 |
| Hu, X | 1 |
| Postu, P | 1 |
| Jung, HA | 1 |
| Ali, MY | 1 |
| Jung, HJ | 1 |
| Jeong, HO | 1 |
| Chung, HY | 1 |
| Choi, JS | 1 |
| Sarell, CJ | 1 |
| Syme, CD | 1 |
| Rigby, SE | 1 |
| Viles, JH | 1 |
| Yanagisawa, D | 1 |
| Shirai, N | 1 |
| Amatsubo, T | 1 |
| Taguchi, H | 1 |
| Hirao, K | 1 |
| Urushitani, M | 1 |
| Morikawa, S | 1 |
| Inubushi, T | 1 |
| Kato, M | 1 |
| Kato, F | 1 |
| Morino, K | 1 |
| Kimura, H | 1 |
| Nakano, I | 1 |
| Yoshida, C | 1 |
| Okada, T | 1 |
| Sano, M | 1 |
| Wada, Y | 1 |
| Wada, KN | 1 |
| Yamamoto, A | 1 |
| Tooyama, I | 1 |
| Ge, XX | 1 |
| Wang, XL | 1 |
| Jiang, P | 1 |
| Xie, Y | 1 |
| Jiang, T | 1 |
| Rong, ZX | 1 |
| Zhang, QZ | 1 |
| Xie, Q | 1 |
| Qiu, ZB | 1 |
| Wang, H | 1 |
| Chen, HZ | 1 |
| Kawai, M | 1 |
| Cras, P | 1 |
| Richey, P | 1 |
| Tabaton, M | 1 |
| Lowery, DE | 1 |
| Gonzalez-DeWhitt, PA | 1 |
| Greenberg, BD | 1 |
| Gambetti, P | 1 |
| Perry, G | 1 |
| Brooksbank, BW | 1 |
| Martinez, M | 1 |
| Yen, PL | 1 |
| Cheng, SS | 1 |
| Wei, CC | 1 |
| Lina, HY | 1 |
| Liao, VH | 1 |
| Chang, ST | 1 |
22 other studies available for methanol and Alzheimer Disease
| Article | Year |
|---|---|
Strawberry (Fragaria × ananassa cv. Romina) methanolic extract attenuates Alzheimer's beta amyloid production and oxidative stress by SKN-1/NRF and DAF-16/FOXO mediated mechanisms in C. elegans.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Caenorhabditis elegans; Caenorhabdi | 2022 |
Hydroxycoumarins and some Flavonoids from
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Flavonoid | 2023 |
Increasing Effect of Citrus natsudaidai on Brain-Derived Neurotrophic Factor.
Topics: Alzheimer Disease; Brain-Derived Neurotrophic Factor; Butanols; Citrus; Humans; Methanol; Water | 2023 |
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer's disease: In Vitro, In Vivo and In Silico approaches.
Topics: Alzheimer Disease; Amnesia; Animals; Antioxidants; Chloroform; Cholinesterase Inhibitors; Glucuronid | 2023 |
Bioassays guided isolation of berberine from Berberis lycium and its neuroprotective role in aluminium chloride induced rat model of Alzheimer's disease combined with insilico molecular docking.
Topics: Acetylcholinesterase; Aluminum Chloride; Alzheimer Disease; Amyloid Precursor Protein Secretases; An | 2023 |
Glucose-mediated protein glycation: Contribution of methanolic extract of Ceratonia siliqua L. in protection and in vitro potential inhibition of acetylcholinesterase.
Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Blood Glucose; Cholinesterase Inhibitors; Chr | 2019 |
BBB-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells.
Topics: Alkaloids; Alzheimer Disease; Animals; Aporphines; Blood-Brain Barrier; Cell Line, Tumor; Flowers; M | 2020 |
Inhibitory Potential of Acroptilon repens against Key Enzymes involved in Alzheimer and Diabetes, Phytochemical Profile, Radical Scavenging, and Antibacterial Activity.
Topics: Acetone; alpha-Amylases; Alzheimer Disease; Anti-Bacterial Agents; Antioxidants; Cholinesterase Inhi | 2021 |
Cannabis Sativa L. Flower and Bud Extracts Inhibited In vitro Cholinesterases and β-Secretase Enzymes Activities: Possible Mechanisms of Cannabis Use in Alzheimer Disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Butyrylcholi | 2022 |
Lactuca capensis reverses memory deficits in Aβ1-42-induced an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Asteraceae; Brain-Derived Neurotrophic | 2018 |
Acetylcholinesterase-inhibitory activity of Iranian plants: Combined HPLC/bioassay-guided fractionation, molecular networking and docking strategies for the dereplication of active compounds.
Topics: Alzheimer Disease; Apiaceae; Biological Assay; Chemical Fractionation; Cholinesterase Inhibitors; Ch | 2018 |
Methanolic extract of
Topics: Alzheimer Disease; Animals; Homocysteine; Hyperhomocysteinemia; Male; Memory Disorders; Methanol; Ne | 2018 |
Methanolic extract of Piper nigrum fruits improves memory impairment by decreasing brain oxidative stress in amyloid beta(1-42) rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Fruit; Male; Maze | 2014 |
Alzheimer's disease and methanol toxicity (part 2): lessons from four rhesus macaques (Macaca mulatta) chronically fed methanol.
Topics: Administration, Oral; Alzheimer Disease; Analysis of Variance; Animals; Brain; Cognition Disorders; | 2014 |
Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1-42) rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antio | 2015 |
Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Anthraquinones; Aspar | 2016 |
Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Binding, Competitive; Circular Dichroism; Copper; Electron | 2009 |
Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Curcumin; Magnetic Resonance Spectroscopy; Methanol; Prote | 2010 |
Determination of Bis(9)-(-)-Meptazinol, a bis-ligand for Alzheimer's disease, in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetics study.
Topics: Alzheimer Disease; Animals; Area Under Curve; Cholinesterase Inhibitors; Chromatography, High Pressu | 2012 |
Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease.
Topics: Acid Phosphatase; Alzheimer Disease; Amyloid beta-Protein Precursor; Hippocampus; Humans; Immunoenzy | 1992 |
Lipid abnormalities in the brain in adult Down's syndrome and Alzheimer's disease.
Topics: Acetals; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Cerebellum; Choline O-Acetyltr | 1989 |
Antioxidant Activities and Reduced Amyloid-β Toxicity of 7-Hydroxycalamenene Isolated from the Essential Oil of Zelkova serrata Heartwood.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Caen | 2016 |