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methanearsonous acid and Cell Transformation, Neoplastic

methanearsonous acid has been researched along with Cell Transformation, Neoplastic in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buck, MJ; Ge, Y; Gong, Z; Olson, JR; Ren, X; Xu, P1
Buck, M; Chen, X; Gaile, D; Ren, X; Tsompana, M; Wang, J; Zhu, J1
Buffington, SE; Eblin, KE; Futscher, BW; Gandolfi, AJ; Jensen, TJ; Wnek, SM1
Futscher, BW; Gandolfi, AJ; Jensen, TJ; Novak, P; Wnek, SM1
Cárdenas-González, MC; Escudero-Lourdes, C; Gandolfi, JA; Medeiros, MK; Wnek, SM1
Futscher, BW; Gandolfi, AJ; Jensen, TJ; Severson, PL; Wnek, SM1
Camarillo, JM; Gandolfi, AJ; Kuhlman, CL; Lau, SS; Liu, KJ; Medeiros, MK; Wnek, SM1
Camarillo, JM; Escudero-Lourdes, C; Gandolfi, AJ; Wu, T1
Chyan, V; Escudero-Lourdes, C; Gandolfi, AJ; Medeiros, M; Novak, P; Wnek, SM; Zheng, X1
Bredfeldt, TG; Eblin, KE; Gandolfi, AJ; Jagadish, B; Mash, EA1
Bredfeldt, TG; Buffington, S; Eblin, KE; Gandolfi, AJ1

Other Studies

11 other study(ies) available for methanearsonous acid and Cell Transformation, Neoplastic

ArticleYear
Inhibition of monomethylarsonous acid (MMA(III))-induced cell malignant transformation through restoring dysregulated histone acetylation.
    Toxicology, 2013, Oct-04, Volume: 312

    Topics: Acetylation; Cell Transformation, Neoplastic; Cells, Cultured; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Organometallic Compounds; Vorinostat

2013
A time-series analysis of altered histone H3 acetylation and gene expression during the course of MMAIII-induced malignant transformation of urinary bladder cells.
    Carcinogenesis, 2017, 04-01, Volume: 38, Issue:4

    Topics: Acetylation; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression; Gene Regulatory Networks; Genome; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Organometallic Compounds; Promoter Regions, Genetic; Up-Regulation; Urinary Bladder

2017
Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling.
    Toxicology, 2009, Jan-08, Volume: 255, Issue:1-2

    Topics: Adenosine Triphosphate; Antioxidants; Blotting, Western; Caspase 3; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Genes, ras; Humans; Mitogen-Activated Protein Kinases; Nucleic Acids; Organometallic Compounds; Oxygen Consumption; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2009
Arsenicals produce stable progressive changes in DNA methylation patterns that are linked to malignant transformation of immortalized urothelial cells.
    Toxicology and applied pharmacology, 2009, Dec-01, Volume: 241, Issue:2

    Topics: Animals; Arsenic; Cell Line; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Mice; Mice, SCID; Oligonucleotide Array Sequence Analysis; Organometallic Compounds; Promoter Regions, Genetic; Urothelium

2009
Low level exposure to monomethyl arsonous acid-induced the over-production of inflammation-related cytokines and the activation of cell signals associated with tumor progression in a urothelial cell model.
    Toxicology and applied pharmacology, 2010, Apr-15, Volume: 244, Issue:2

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Cytokines; Humans; Inflammation Mediators; Organometallic Compounds; Signal Transduction; Urinary Bladder Neoplasms; Urothelium

2010
Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12 weeks of low-level exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 116, Issue:1

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Dose-Response Relationship, Drug; Humans; Mice; Mice, SCID; Organometallic Compounds; Reverse Transcriptase Polymerase Chain Reaction; Urinary Bladder Neoplasms

2010
Interdependent genotoxic mechanisms of monomethylarsonous acid: role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells.
    Toxicology and applied pharmacology, 2011, Nov-15, Volume: 257, Issue:1

    Topics: Blotting, Western; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chlorides; Comet Assay; DNA Damage; Flow Cytometry; Humans; Organometallic Compounds; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium; Zinc Compounds

2011
Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells.
    Toxicology and applied pharmacology, 2012, Jan-01, Volume: 258, Issue:1

    Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Interleukin-8; Male; Mice; Mice, SCID; Neoplasm Invasiveness; Organometallic Compounds; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Urinary Bladder Neoplasms; Urothelium

2012
Global gene expression changes in human urothelial cells exposed to low-level monomethylarsonous acid.
    Toxicology, 2012, Jan-27, Volume: 291, Issue:1-3

    Topics: Apoptosis Regulatory Proteins; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; Extracellular Matrix; Gene Expression; Gene Expression Profiling; Humans; Inflammation; Mitogen-Activated Protein Kinases; Organometallic Compounds; Oxidative Stress; Protein Array Analysis; Real-Time Polymerase Chain Reaction; Signal Transduction; Urinary Bladder Neoplasms; Urothelium

2012
Monomethylarsonous acid induces transformation of human bladder cells.
    Toxicology and applied pharmacology, 2006, Oct-01, Volume: 216, Issue:1

    Topics: Animals; Cell Line; Cell Nucleus; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Ki-67 Antigen; Mice; Mice, SCID; Neoplasms, Experimental; Organometallic Compounds; Time Factors; Transplantation, Heterologous; Urinary Bladder; Urothelium

2006
Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:2

    Topics: Cell Line; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Mitogens; Organometallic Compounds; Protein Transport; Proto-Oncogene Proteins c-jun; Signal Transduction; Urinary Bladder; Urinary Bladder Neoplasms

2007