Page last updated: 2024-10-16

methane and Mesothelioma

methane has been researched along with Mesothelioma in 47 studies

Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed)
methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).

Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Mesothelioma has been a relatively rare cancer but is socially important due to its association with asbestos exposure, caused by modern industrial development."2.61Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: Toward the era of mesothelioma prevention. ( Toyokuni, S, 2019)
"- Although many mesotheliomas are related to asbestos exposure, not all are, and there is increasing information on other causes of mesothelioma."2.58Malignant Mesothelioma and Its Non-Asbestos Causes. ( Attanoos, RL; Churg, A; Galateau-Salle, F; Gibbs, AR; Roggli, VL, 2018)
"Currently rates of mesothelioma are rising and estimates indicate that the incidence of mesothelioma will peak within the next 10-15 years in the western world, while in Japan the peak is predicted not to occur until 40 years from now."2.52Reactive oxygen species a double-edged sword for mesothelioma. ( Benedetti, S; Catalani, S; Galati, R; Nuvoli, B, 2015)
" Therefore carbon nanotubes might display toxic effects and the extent of the toxicity is more specifically directed to lung and pleura."2.47Carbon nanotubes and pleural damage: perspectives of nanosafety in the light of asbestos experience. ( Stella, GM, 2011)
"malignant mesothelioma and lung cancer) is largely unknown."2.46Biopersistent fiber-induced inflammation and carcinogenesis: lessons learned from asbestos toward safety of fibrous nanomaterials. ( Nagai, H; Toyokuni, S, 2010)
" In this regard, we have attempted to elucidate the pharmacodynamics and safety of nanomaterials in order to develop novel, safe nanomaterials and to establish scientifically based regulations."2.46[Nano-safety science for assuring the safety of nanomaterials]. ( Tsutsumi, Y; Yoshikawa, T; Yoshioka, Y, 2010)
"Mesothelioma is a cancer of the lung pleura primarily associated with inhalation of asbestos fibers."1.62Osteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro. ( Bonner, JC; Sridharan, S; Taylor-Just, A, 2021)
"MWCNT-7 has been shown to induce malignant mesothelioma when administered by intrascrotal or intraperitoneal injection in rats and mice, and an inhalation study demonstrated that rats exposed to respirable MWCNT-7 developed lung tumors."1.51MWCNT-7 administered to the lung by intratracheal instillation induces development of pleural mesothelioma in F344 rats. ( Abdelgied, M; Alexander, DB; Alexander, WT; El-Gazzar, AM; Higuchi, H; Hirose, A; Naiki-Ito, A; Numano, T; Saleh, D; Suzuki, S; Takahashi, S; Takase, H; Tsuda, H, 2019)
"Mesothelioma is a fatal tumor of the pleura and is strongly associated with asbestos exposure."1.46Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). ( Bennett, J; Bushell, M; Chernova, T; Dinsdale, D; Donaldson, K; Dudek, KM; Galavotti, S; Greaves, P; Grosso, S; Le Quesne, J; MacFarlane, M; Murphy, FA; Nakas, A; Poland, CA; Powley, IR; Schinwald, A; Sun, XM; Willis, AE; Zacarias-Cabeza, J, 2017)
"Malignant mesothelioma is one of the most aggressive forms of cancer known."1.39Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2. ( Castranova, V; Dinu, CZ; Liu, Y; Lohcharoenkal, W; Rojanasakul, Y; Stueckle, TA; Wang, L, 2013)
" Here, we report a dose-response study; three groups of p53 heterozygous mice (n = 20) were given a single intraperitoneal injection of 300 μg/mouse of μm-MWCNT (corresponding to 1 × 10(8) fibers), 30 μg/mouse (1 × 10(7)) or 3 μg/mouse (1 × 10(6)), respectively, and observed for up to 1 year."1.38Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice. ( Futakuchi, M; Hirose, A; Kanno, J; Takagi, A; Tsuda, H, 2012)
" Conditioned cell culture media of macrophages treated with multi-walled carbon nanotubes and crocidolite and the supernatants of pleural cavity lavage fluid from the dosed rats increased mesothelial cell proliferation in vitro, suggesting that mesothelial proliferative lesions were induced by inflammatory events in the lung and pleural cavity and likely mediated by macrophages."1.38Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats. ( Alexander, DB; Fukamachi, K; Futakuchi, M; Hirose, A; Kanno, J; Nakae, D; Ogata, A; Omori, T; Sakamoto, Y; Shimizu, H; Suzui, M; Tsuda, H; Xu, J; Yanagihara, K, 2012)
"Mesotheliomas were invasive to adjacent organs and tissues, and frequently metastasized into the pleura."1.35Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. ( Fukumori, N; Hirose, A; Imai, K; Maekawa, A; Nakae, D; Nishimura, T; Ogata, A; Ohashi, N; Sakamoto, Y; Tayama, K, 2009)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (14.89)29.6817
2010's30 (63.83)24.3611
2020's10 (21.28)2.80

Authors

AuthorsStudies
Saleh, DM2
Luo, S1
Ahmed, OHM2
Alexander, DB7
Alexander, WT4
Gunasekaran, S2
El-Gazzar, AM3
Abdelgied, M4
Numano, T6
Takase, H3
Ohnishi, M5
Tomono, S1
Hady, RHAE1
Fukamachi, K4
Kanno, J11
Hirose, A14
Xu, J4
Suzuki, S2
Naiki-Ito, A3
Takahashi, S4
Tsuda, H9
Hojo, M4
Maeno, A3
Sakamoto, Y7
Ohnuki, A2
Tada, Y1
Yamamoto, Y3
Ikushima, K2
Inaba, R1
Suzuki, J3
Taquahashi, Y3
Yokota, S1
Kobayashi, N1
Goto, Y1
Inomata, A4
Nakae, D6
Pandey, SK1
Machlof-Cohen, R1
Santhanam, M1
Shteinfer-Kuzmine, A1
Shoshan-Barmatz, V1
Janosikova, M1
Nakladalova, M1
Stepanek, L1
Nel, A1
Shimizu, M1
Ishimaru, N1
Sridharan, S1
Taylor-Just, A1
Bonner, JC1
Moriyasu, T1
Orsi, M2
Palmai-Pallag, M2
Yakoub, Y2
Ibouraadaten, S2
De Beukelaer, M1
Bouzin, C1
Bearzatto, B1
Ambroise, J1
Gala, JL1
Brusa, D1
Lison, D3
Huaux, F3
Fukushima, S1
Kasai, T1
Umeda, Y1
Sasaki, T1
Matsumoto, M1
Chernova, T1
Murphy, FA3
Galavotti, S1
Sun, XM1
Powley, IR1
Grosso, S1
Schinwald, A2
Zacarias-Cabeza, J1
Dudek, KM1
Dinsdale, D1
Le Quesne, J1
Bennett, J1
Nakas, A1
Greaves, P1
Poland, CA3
Donaldson, K4
Bushell, M1
Willis, AE1
MacFarlane, M1
Port, J1
Murphy, DJ1
Attanoos, RL1
Churg, A1
Galateau-Salle, F1
Gibbs, AR1
Roggli, VL1
Kosugi, Y1
Watanabe, K1
Suzuki, T1
Toyokuni, S6
Ito, F1
Hisashi, H1
Yoshida, GJ1
Higuchi, H1
Saleh, D1
Lohcharoenkal, W1
Wang, L1
Stueckle, TA1
Dinu, CZ1
Castranova, V4
Liu, Y1
Rojanasakul, Y1
Nagai, H3
Okazaki, Y3
Chew, SH2
Misawa, N2
Miyata, Y2
Shinohara, H2
Sargent, LM1
Porter, DW1
Staska, LM1
Hubbs, AF1
Lowry, DT1
Battelli, L1
Siegrist, KJ1
Kashon, ML1
Mercer, RR1
Bauer, AK1
Chen, BT1
Salisbury, JL1
Frazer, D1
McKinney, W1
Andrew, M1
Tsuruoka, S2
Endo, M1
Fluharty, KL1
Reynolds, SH1
Futakuchi, M4
Suzui, M3
Omori, T3
Rittinghausen, S1
Hackbarth, A1
Creutzenberg, O1
Ernst, H1
Heinrich, U1
Leonhardt, A1
Schaudien, D1
Benedetti, S1
Nuvoli, B1
Catalani, S1
Galati, R1
Maruyama, K1
Haniu, H1
Saito, N1
Matsuda, Y1
Tsukahara, T1
Kobayashi, S1
Tanaka, M2
Aoki, K1
Takanashi, S1
Okamoto, M1
Kato, H1
Wang, Y1
Shi, L1
Kohda, H1
Taki, K1
Nishioka, T1
Hirayama, T1
Nagasawa, H1
Yamashita, Y2
Jiegou, X1
d'Ursel de Bousies, V1
Parent, MA1
Uwambayinema, F1
Devosse, R1
Panin, N2
van der Bruggen, P1
Bailly, C1
Marega, R1
Marbaix, E1
Ichihara, G2
Tanioka, A1
Miyazawa, K1
Stone, V2
Seaton, A1
Tran, L1
Aitken, R1
Poland, C1
Tokunaga, H1
Fukumori, N2
Tayama, K1
Maekawa, A1
Imai, K1
Nishimura, T2
Ohashi, N2
Ogata, A3
Muller, J1
Delos, M1
Rabolli, V1
Pacurari, M1
Vallyathan, V1
Duffin, R1
Aschberger, K1
Johnston, HJ1
Aitken, RJ1
Hankin, SM1
Peters, SA1
Tran, CL1
Christensen, FM1
Yoshioka, Y1
Yoshikawa, T1
Tsutsumi, Y1
Dikensoy, O1
Bayram, H1
Stella, GM1
Akatsuka, S1
Ishihara, T1
Yamashita, K1
Yoshikawa, Y1
Yasui, H1
Jiang, L1
Ohara, H1
Takahashi, T1
Kostarelos, K1
Takagi, A2
Shimizu, H1
Yanagihara, K1
Kitajima, S1

Reviews

13 reviews available for methane and Mesothelioma

ArticleYear
Current causes of mesothelioma: how has the asbestos ban changed the perspective?
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2023, Volume: 167, Issue:2

    Topics: Adolescent; Asbestos; Environmental Exposure; Female; Humans; Lung Neoplasms; Mesothelioma; Mesothel

2023
Carbon nanotube pathogenicity conforms to a unified theory for mesothelioma causation by elongate materials and fibers.
    Environmental research, 2023, 08-01, Volume: 230

    Topics: Asbestos; Humans; Inflammation; Mesothelioma; Nanotubes, Carbon; Virulence

2023
Malignant Mesothelioma and Its Non-Asbestos Causes.
    Archives of pathology & laboratory medicine, 2018, Volume: 142, Issue:6

    Topics: Asbestos, Serpentine; Europe; Female; Germ-Line Mutation; Humans; Lung Neoplasms; Male; Mesothelioma

2018
Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: Toward the era of mesothelioma prevention.
    Free radical biology & medicine, 2019, Volume: 133

    Topics: Animals; Asbestos; Carcinogenesis; Ferroptosis; Humans; Iron; Iron Overload; Lung Neoplasms; Mesothe

2019
Reactive oxygen species a double-edged sword for mesothelioma.
    Oncotarget, 2015, Jul-10, Volume: 6, Issue:19

    Topics: Cell Transformation, Neoplastic; Humans; Mesothelioma; Nanotubes, Carbon; Oxidative Stress; Reactive

2015
[Hazard identification of nanomaterials].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:12

    Topics: Animals; Asbestos; Fullerenes; Humans; Mesothelioma; Mice; Nanostructures; Nanotubes, Carbon; Partic

2008
Single- and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans?
    Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:5

    Topics: Asbestos; Carcinogens; Carcinoma, Bronchogenic; DNA Damage; Epithelium; Humans; Mesothelioma; Mitoge

2010
Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma.
    Particle and fibre toxicology, 2010, Mar-22, Volume: 7

    Topics: Air Pollutants; Animals; Asbestos; Disease Models, Animal; Epithelium; Humans; Mesothelioma; Metabol

2010
Biopersistent fiber-induced inflammation and carcinogenesis: lessons learned from asbestos toward safety of fibrous nanomaterials.
    Archives of biochemistry and biophysics, 2010, Oct-01, Volume: 502, Issue:1

    Topics: Animals; Asbestos; Humans; In Vitro Techniques; Inflammation; Macrophage Activation; Mesothelioma; M

2010
Review of carbon nanotubes toxicity and exposure--appraisal of human health risk assessment based on open literature.
    Critical reviews in toxicology, 2010, Volume: 40, Issue:9

    Topics: Asbestos; Environmental Health; Humans; Inhalation Exposure; Mesothelioma; Nanotubes, Carbon; Occupa

2010
[Nano-safety science for assuring the safety of nanomaterials].
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 2010, Volume: 65, Issue:4

    Topics: Animals; Chemical Phenomena; Humans; Mesothelioma; Mice; Nanostructures; Nanotechnology; Nanotubes,

2010
The current data on nanoparticles and pleura.
    Tuberkuloz ve toraks, 2010, Volume: 58, Issue:4

    Topics: Animals; Disease Models, Animal; Humans; Mesothelioma; Nanoparticles; Nanotubes, Carbon; Particle Si

2010
Carbon nanotubes and pleural damage: perspectives of nanosafety in the light of asbestos experience.
    Biointerphases, 2011, Volume: 6, Issue:2

    Topics: Asbestos; Humans; Mesothelioma; Models, Biological; Nanotubes, Carbon; Occupational Exposure; Occupa

2011

Other Studies

34 other studies available for methane and Mesothelioma

ArticleYear
Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study.
    Particle and fibre toxicology, 2022, 04-22, Volume: 19, Issue:1

    Topics: Animals; Inhalation Exposure; Lung; Lung Neoplasms; Mesothelioma; Nanotubes, Carbon; Pleura; Rats

2022
Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats.
    Particle and fibre toxicology, 2022, 05-19, Volume: 19, Issue:1

    Topics: Animals; Carcinogens; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Nanotubes, Carbon; Rats

2022
Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks.
    Biomolecules, 2022, 06-27, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Humans; Inflammation; Mesothelioma; Mice; Nanotubes, Carbon; RNA, Small Interfer

2022
Continuous infiltration of small peritoneal macrophages in the mouse peritoneum through CCR2-dependent and -independent routes during fibrosis and mesothelioma development induced by a multiwalled carbon nanotube, MWNT-7.
    The Journal of toxicological sciences, 2023, Volume: 48, Issue:12

    Topics: Animals; Fibrosis; Macrophages, Peritoneal; Mesothelioma; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat.
    Particle and fibre toxicology, 2020, 10-15, Volume: 17, Issue:1

    Topics: Air Pollutants; Animals; Asbestos, Crocidolite; Carcinogenicity Tests; Inhalation Exposure; Lung; Lu

2020
Osteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 73

    Topics: Animals; Biomarkers; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Male; Mesotheliom

2021
Histological sequence of the development of rat mesothelioma by MWCNT, with the involvement of apolipoproteins.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Animals; Apolipoproteins; Ascitic Fluid; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Cholesterol

2021
Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Cell Differentiation; Cell Proliferation; Histocompatibility Antigens Class II; Inflammatio

2021
Carcinogenicity of multi-walled carbon nanotubes: challenging issue on hazard assessment.
    Journal of occupational health, 2018, Jan-25, Volume: 60, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma; Humans; Inhalation Exposure; Lung; Lung Neoplasms; Maximum Allow

2018
Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf).
    Current biology : CB, 2017, Nov-06, Volume: 27, Issue:21

    Topics: Aged; Animals; Asbestos; Carcinogenesis; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinas

2017
Mesothelioma: Identical Routes to Malignancy from Asbestos and Carbon Nanotubes.
    Current biology : CB, 2017, 11-06, Volume: 27, Issue:21

    Topics: Animals; Asbestos; Humans; Inflammation; Lung Neoplasms; Mesothelioma; Mice; Nanotubes, Carbon

2017
Comparative study for carcinogenicity of 7 different multi-wall carbon nanotubes with different physicochemical characteristics by a single intraperitoneal injection in male Fischer 344 rats.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:10

    Topics: Animals; Chemical Phenomena; Injections, Intraperitoneal; Male; Mesothelioma; Microscopy, Electron,

2018
Polymer coating on carbon nanotubes into Durobeads is a novel strategy for human environmental safety.
    Nagoya journal of medical science, 2018, Volume: 80, Issue:4

    Topics: Animals; Cell Line; Humans; Male; Mesothelioma; Microscopy, Electron, Scanning; Nanotubes, Carbon; P

2018
Beyond Stanton and Pott hypothesis; carbon nanotubes-induced malignant mesothelioma as a disease of gene loss.
    Journal of occupational health, 2019, Volume: 61, Issue:2

    Topics: Animals; Asbestos; Genes, p16; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice;

2019
MWCNT-7 administered to the lung by intratracheal instillation induces development of pleural mesothelioma in F344 rats.
    Cancer science, 2019, Volume: 110, Issue:8

    Topics: Animals; Asbestos, Crocidolite; Injections, Intraperitoneal; Lung; Lung Neoplasms; Male; Mesotheliom

2019
Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2.
    ACS nano, 2013, Sep-24, Volume: 7, Issue:9

    Topics: Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dose

2013
Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats.
    Pathology international, 2013, Volume: 63, Issue:9

    Topics: Animals; Asbestos; Cell Transformation, Neoplastic; Disease Models, Animal; Environmental Health; Fe

2013
Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.
    Particle and fibre toxicology, 2014, Jan-09, Volume: 11

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenoma; Animals; Bronchoalveolar Lavage Fluid; Fluorescent

2014
Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes.
    Cancer science, 2014, Volume: 105, Issue:7

    Topics: Animals; Cell Proliferation; Cytokines; Fibrosis; Inflammation; Lung; Male; Mesothelioma; Nanotubes,

2014
The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats.
    Particle and fibre toxicology, 2014, Nov-20, Volume: 11

    Topics: Abdominal Neoplasms; Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug;

2014
Endocytosis of Multiwalled Carbon Nanotubes in Bronchial Epithelial and Mesothelial Cells.
    BioMed research international, 2015, Volume: 2015

    Topics: Apoptosis; Asbestos; Autophagy; Bronchi; Endocytosis; Epithelial Cells; Humans; Mesothelioma; Nanotu

2015
Role of hemoglobin and transferrin in multi-wall carbon nanotube-induced mesothelial injury and carcinogenesis.
    Cancer science, 2016, Volume: 107, Issue:3

    Topics: Adsorption; Animals; Carcinogens; Cell Line; Epithelium; Female; Hemoglobins; Male; Mesothelioma; Na

2016
Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors.
    Cancer science, 2016, Volume: 107, Issue:7

    Topics: Animals; Carcinogenesis; Incidence; Inflammation; Lung; Lung Neoplasms; Male; Mesothelioma; Nanotube

2016
Mesothelioma response to carbon nanotubes is associated with an early and selective accumulation of immunosuppressive monocytic cells.
    Particle and fibre toxicology, 2016, 08-23, Volume: 13, Issue:1

    Topics: Animals; Carcinogens; Heterografts; Humans; Male; Mesothelioma; Mice; Mice, Inbred C57BL; Monocytes;

2016
Space elevators, tennis racquets, and mesothelioma.
    The Lancet. Oncology, 2008, Volume: 9, Issue:7

    Topics: Humans; Mesothelioma; Nanotubes, Carbon; Technology Transfer

2008
Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube.
    The Journal of toxicological sciences, 2008, Volume: 33, Issue:3

    Topics: Animals; Asbestos; Genes, p53; Injections, Intraperitoneal; Mesothelioma; Mice; Nanotubes, Carbon; P

2008
Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube.
    The Journal of toxicological sciences, 2008, Volume: 33, Issue:3

    Topics: Animals; Genes, p53; Injections, Intraperitoneal; Mesothelioma; Mice; Nanotubes, Carbon; No-Observed

2008
Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:1

    Topics: Anemia; Animals; Asbestos, Crocidolite; Ascites; Autopsy; Carboxymethylcellulose Sodium; Carcinogens

2009
Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Abdominal Neoplasms; Animals; Asbestos, Crocidolite; Biological Assay; Carcinogenicity Tests; Carcin

2009
Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Dec-06, Volume: 108, Issue:49

    Topics: Animals; Cell Line; Cells, Cultured; Comparative Genomic Hybridization; Cyclin-Dependent Kinase Inhi

2011
The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells.
    Particle and fibre toxicology, 2012, Apr-03, Volume: 9

    Topics: Cell Line, Tumor; Cell Survival; Culture Media, Conditioned; Cytokines; Dose-Response Relationship,

2012
Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice.
    Cancer science, 2012, Volume: 103, Issue:8

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Genes, p53; Heterozygote; Injections, Intrap

2012
Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats.
    Cancer science, 2012, Volume: 103, Issue:12

    Topics: Animals; Asbestos, Crocidolite; Cell Proliferation; Lung; Macrophages, Alveolar; Male; Mesothelioma;

2012
Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube.
    The Journal of toxicological sciences, 2008, Volume: 33, Issue:1

    Topics: Animals; Carcinogens; Gastrointestinal Tract; Genes, p53; Injections, Intraperitoneal; Kidney; Male;

2008