methamphetamine has been researched along with Encephalopathy, Toxic in 177 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 57 (32.20) | 29.6817 |
| 2010's | 89 (50.28) | 24.3611 |
| 2020's | 31 (17.51) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L; Liu, M; Wang, Y; Zhao, W; Zhao, YL | 3 |
| Gibson, AS; Keefe, KA; West, PJ | 1 |
| Čechová, B; Šlamberová, R | 1 |
| Cao, C; Chen, G; Li, M; Liu, Z; Wang, L; Xie, S; Xu, X; Zhang, J | 1 |
| Ding, J; Fan, H; He, Y; Huang, J; Li, Y; Qiu, P; Wang, X; Wang, Z; Xie, Q | 1 |
| Chen, L; Ru, Q; Wu, Y; Xiong, Q; Xu, G; Yang, J | 1 |
| Garmabi, B; Khaksari, M; Khastar, H; Mohaddes, R; Mohseni, F; Rezvani, F | 1 |
| Jeong, JH; Katila, N; Lee, S; Seo, JH; Shrestha, P; Yook, S | 1 |
| Biagioni, F; Busceti, CL; Ferrucci, M; Fornai, F; Frati, A; Lazzeri, G; Lenzi, P; Puglisi-Allegra, S | 1 |
| Ding, J; Fan, H; Gu, C; He, Y; Huang, J; Li, Y; Qi, X; Qiu, P; Wang, X; Wang, Z; Xie, Q | 1 |
| Chen, Q; Chen, X; Huang, Y; Li, L; Qiao, D; Xu, L | 1 |
| Pang, L; Wang, Y | 1 |
| Bing, G; Dang, DK; Jeong, JH; Kim, DJ; Kim, HC; Nah, SY; Pham, DT; Sharma, G; Sharma, N; Shin, EJ; Trinh, QD | 1 |
| Chen, L; Guo, L; Liao, L; Lu, S; Xiong, K; Yan, H; Yan, J; Yan, W; Zhang, B | 1 |
| Ding, J; Fan, H; He, Y; Li, C; Lian, Y; Meng, Y; Qiu, P | 1 |
| Chen, LJ; Li, JH; Qu, D; Tan, XH; Wang, HJ; Wang, Q; Xie, XL; Xu, JT; Zhang, KK | 1 |
| Mead, J; Parrott, A | 1 |
| Chen, Y; Hall, FS; Saber, YH; Tran, HTN | 1 |
| Moszczynska, A | 1 |
| Ding, J; He, Y; Hu, S; Huang, J; Li, C; Meng, Y; Qiu, P | 1 |
| Chu, H; Guo, Y; Han, Y; Kong, L; Ma, H; Meng, X; Wang, C; Zhang, C | 1 |
| Ding, J; He, Y; Huang, J; Li, C; Lian, Y; Meng, Y; Qiu, P; Wang, Y | 1 |
| Ding, J; Fan, H; He, Y; Li, C; Meng, Y; Qiu, P | 1 |
| Chen, LJ; Li, JH; Liu, JL; Wang, LB; Wang, Q; Xie, XL; Xu, LL; Yoshida, JS; Zhang, KK; Zhi, X | 1 |
| Cao, M; Fan, R; He, J; Li, X; Liu, Y; Ruan, Y; Xu, M; Xu, X; Zhou, W | 1 |
| Su, H; Wu, M; Zhao, M | 1 |
| Chen, L; Cheng, L; Gu, YJ; Wang, Y; Zhou, MY | 1 |
| Balestrini, L; Biagioni, F; Busceti, CL; Ferrucci, M; Fornai, F; Fornasiero, A; Lazzeri, G; Leone, S; Pompili, E; Puglisi-Allegra, S; Ryskalin, L | 1 |
| Cadet, JL; Daiwile, AP; Jayanthi, S | 1 |
| Bass, CE; Bhimani, RV; Park, J; Szalkowski, C; Vik, M; Wakabayashi, KT | 1 |
| Dimitriou, A; Efthimiou, P; Karveli, M; Lagadinou, M; Skaltsa, M; Tsigkou, A; Velissaris, D; Zareifopoulos, N | 1 |
| Greig, NH; Kim, PP; Lu, T; Luo, Y | 1 |
| Dang, DK; Jang, CG; Jeong, JH; Kim, HC; Ledent, C; Mai, AT; Nabeshima, T; Nah, SY; Onaivi, ES; Shin, EJ; Yamamoto, T | 1 |
| Cusick, M | 1 |
| Amaral, C; Bastos, ML; Carvalho, F; Carvalho, M; Correia-da-Silva, G; Duarte, JA; Guedes de Pinho, P; Valente, MJ | 1 |
| Bi, J; Feng, X; Kong, W; Liu, W; Wang, L; Wang, Z; Wu, H; Wu, J; Xu, X; Yu, B; Yu, X; Zhang, H; Zhu, R | 1 |
| Callan, SP; Moszczynska, A | 1 |
| Angoa-Perez, M; Anneken, JH; Crich, D; Kuhn, DM; Sati, GC | 3 |
| Baumann, MH; Elmore, JS; Janowsky, A; Miner, NB; Phillips, TJ | 1 |
| Borgmann, K; Ghorpade, A | 1 |
| Gao, J; Guo, Z; Han, M; Huang, Y; Liang, J; Liu, J; Liu, X; Tu, S; Xu, S; Zhang, J | 1 |
| Du, SH; He, JT; Wang, Q; Wang, ZT; Xiao, HQ; Xie, XL; Xue, Y; Zhou, WT | 1 |
| Górska, A; Gołembiowska, K; Kajta, M; Kamińska, K; Kreiner, G; Noworyta-Sokołowska, K; Rzemieniec, J; Wnuk, A; Wojtas, A | 1 |
| Deng, WT; Lee, HT; Liao, YH; Sun, LH; Wang, YH; Yu, L | 1 |
| Chen, L; Li, C; Li, Y; Ru, Q; Tian, X; Xiong, Q; Zhou, M | 1 |
| Heysieattalab, S; Khoshbouei, H; Shaerzadeh, F; Streit, WJ | 1 |
| Chang, AJ; Jenab, S; Klambatsen, A; Nygard, SK; Quinones, V | 1 |
| Medina-Kirchner, C; Torres, CA | 1 |
| Ahmadiani, A; Dargahi, L; Heravi, M; Valian, N | 1 |
| Lopez-Rodriguez, AB; Viveros, MP | 1 |
| Maranella, E | 1 |
| Chen, L; Ding, J; Li, C; Lian, Y; Meng, Y; Qiu, P; Sun, L | 1 |
| Friend, DM; Keefe, KA | 1 |
| Aparicio, MB; Engelmann, AJ; Grant, Y; Kim, A; Mandyam, CD; Sobieraj, JC; Yuan, CJ | 1 |
| Barker-Haliski, ML; Garris, PA; Howard, CD; Keefe, KA; Pastuzyn, ED | 1 |
| Afanador, L; Angulo, JA; Baker, L; Diaz, C; Mexhitaj, I; Ordonez, D | 1 |
| Ceccatelli, S | 1 |
| Ares-Santos, S; Granado, N; Moratalla, R | 1 |
| Coop, A; Matsumoto, RR; McCurdy, CR; Robson, MJ; Seminerio, MJ | 1 |
| Blum, K; Borsten, J; Febo, M; Foster Olive, M; Giordano, J; Gold, MS; Hauser, M; Wang, KK | 1 |
| Bae, E; He, Y; Reiner, DJ; Shen, H; Wang, Y; Yu, SJ | 1 |
| Angoa-Pérez, M; Francescutti, DM; Herrera-Mundo, N; Kane, MJ; Kuhn, DM | 1 |
| Collins, SA; Halpin, LE; Yamamoto, BK | 1 |
| Ahuja, M; Dhanasekaran, M; Karuppagounder, SS; Suppiramaniam, V; Thrash-Williams, B; Uthayathas, S | 1 |
| Fujita, Y; Hashimoto, K; Ma, M; Ren, Q; Wu, J; Zhang, JC | 1 |
| Bai, J; Jia, J; Li, Y; Lv, T; Shi, Z | 1 |
| Cunha, RA; de Oliveira, PA; Dias, AI; Fontes Ribeiro, CA; Freitas, HJ; Mendes, SM; Neves, AF; Pereira, FC; Pita, I; Prediger, RD; Silva, CD; Viana, SD | 1 |
| Byers, DL; Garris, PA; Howard, CD; Keefe, KA; Pastuzyn, ED; Robinson, JD | 1 |
| Abad, S; Camarasa, J; Escubedo, E; López-Arnau, R; Martínez-Clemente, J; Pubill, D | 1 |
| Chavant, F; Duranti, A; Francheteau, M; Gennequin, B; Maccarrone, M; Makriyannis, A; Nader, J; Rapino, C; Solinas, M; Thiriet, N | 1 |
| Chauhan, H; Killinger, BA; Miller, CV; Moszczynska, A | 1 |
| Chen, CX; Chen, L; Huang, EP; Huang, WY; Liu, C; Qiu, PM; Wang, AF; Wang, HJ; Wu, XF; Xie, WB | 1 |
| Huang, E; Le, C; Lin, Z; Liu, C; Qiao, D; Qiu, P; Wang, H; Xie, WB; Xu, J | 1 |
| Camarasa, J; Escubedo, E; López-Arnau, R; Martínez-Clemente, J; Pubill, D | 1 |
| Govitrapong, P; Wongprayoon, P | 1 |
| Bai, X; Di, X; Shen, Q; Yu, S; Zhu, L | 1 |
| Cory-Slechta, DA; McConnell, SE; O'Banion, MK; Olschowka, JA; Opanashuk, LA | 1 |
| Ramkissoon, A; Wells, PG | 1 |
| Costa, G; García-Montes, JR; Granado, N; Khairnar, A; Moratalla, R; Morelli, M; Porceddu, PF; Simola, N; Tizabi, Y | 1 |
| Furlong, TM; Keefe, KA; Leavitt, LS; Son, JH | 1 |
| Aguilera, J; Granado, N; Mendieta, L; Moratalla, R; Tizabi, Y | 1 |
| Bowyer, JF; Hanig, JP; Miller, DB; O'Callaghan, JP; Sarkar, S; Tranter, KM | 1 |
| Kelly, JP; McDonnell-Dowling, K | 1 |
| Fone, KC; Green, AR; King, MV; Shortall, SE | 1 |
| Ananth, M; Cadet, JL; Chachati, G; Delis, F; Gold, MS; Grant, SC; Kim, R; Masad, I; Muniz, JA; Rocco, MJ; Thanos, PK; Volkow, ND | 1 |
| Jablonski, SA; Vorhees, CV; Williams, MT | 1 |
| Dang, DK; Hong, JS; Jang, CG; Jeong, JH; Kim, HC; Lee, YH; Lee, YS; Nabeshima, T; Nam, Y; Park, KT; Shin, EJ; Tran, HQ | 1 |
| Liu, J; Liu, Y; Xie, A; Xiong, H; Xu, E; Zhao, J | 1 |
| Busardò, FP; di Luca, A; Mannocchi, G; Marinelli, E; Pacifici, R; Pantano, F; Tittarelli, R | 1 |
| Gudelsky, GA; Herring, NR; Schaefer, TL; Vorhees, CV; Williams, MT | 1 |
| Brown, S; Fishback, JA; Liu, Y; Matsumoto, RR; Shaikh, J | 1 |
| Cadet, JL; Krasnova, IN | 2 |
| Francescutti-Verbeem, DM; Kuhn, DM; Thomas, DM | 2 |
| Hwang, M; Jeon, JP; Lee, MJ; Yang, CH | 1 |
| Asanuma, M; Kita, T; Miyazaki, I; Takeshima, M; Wagner, GC | 1 |
| Camarasa, J; Chipana, C; Escubedo, E; García-Ratés, S; Pubill, D | 1 |
| Biezonski, DK; Meyer, JS | 1 |
| Darvesh, AS; Dluzen, DE; McDermott, JL | 1 |
| Bini, V; Bortolato, M; Castelli, MP; Collu, M; Ennas, MG; Frau, R; Gessa, GL; Loriga, R; Luesu, W | 1 |
| Ali, SF; Bondy, SC | 1 |
| Darvas, M; Hatzidimitriou, G; McCann, UD; Palmiter, RD; Ricaurte, GA; Sotak, B; Yuan, J | 1 |
| Barrett, DA; Colado, MI; Feng, S; Gutierrez-Lopez, MD; Llopis, N; O'Shea, E | 1 |
| Angoa Pérez, M; Francescutti-Verbeem, DM; Kuhn, DM; Shah, MM; Thomas, DM | 1 |
| Foley, PL; Goudie, AR; Lauder, GD; O'Riordan, JI; Sammler, EM; Wilson, SJ | 1 |
| Cai, Z; Fan, LW; Lin, RC; Ma, T; Pang, Y; Rhodes, PG; Simpson, KL; Tien, LT; Zheng, B | 1 |
| Kiyatkin, EA; Sharma, HS | 1 |
| Miller, DK; Rodvelt, KR | 1 |
| Bourque, M; Di Paolo, T; Dluzen, DE; Liu, B | 2 |
| Ares-Santos, S; Colado, MI; Granado, N; Martin, ED; Moratalla, R; O'Shea, E; Oliva, I | 1 |
| Largeron, M; Martinez, CM; McCann, U; Mechan, A; Mueller, M; Neudörffer, A; Ricaurte, GA | 1 |
| Daberkow, DP; Garris, PA; Howard, CD; Keefe, KA | 1 |
| Chen, H; Fujita, Y; Hashimoto, K; Ishima, T; Iyo, M; Wu, J; Zhang, J | 1 |
| Fishman, I; Gaskins, R; Gold, MS; Kobeissy, FH; Mitzelfelt, JD; Morgan, D; Wang, KK; Zhang, Z | 1 |
| Kitamura, O; Takeichi, T; Wang, EL | 1 |
| Hwang, M; Jang, EY; Lee, JR; Park, KA; Yang, CH | 1 |
| Cheer, JF; Glick, SD; Morra, JT | 1 |
| Fox, HS; Ninemire, C; Pendyala, G | 1 |
| Kaushal, N; Matsumoto, RR; McCurdy, CR; Robson, MJ; Seminerio, MJ | 1 |
| Hansen, R; Kaushal, N; Matsumoto, RR; McCurdy, CR; Seminerio, MJ; Zhang, HT | 1 |
| Barker-Haliski, ML; Keefe, KA; Oldenburger, K | 1 |
| Halpin, LE; Yamamoto, BK | 1 |
| Fricks-Gleason, AN; Friend, DM; Keefe, KA; Son, JH | 1 |
| Killinger, B; Liu, B; Moszczynska, A; Schneider, B; Traini, R | 1 |
| Ali, SF; Itzhak, Y; Martin, JL | 1 |
| Benkovic, SA; Miller, DB; O'Callaghan, JP; Sriram, K | 1 |
| Bardo, MT; Cass, WA; Gehrke, BJ; Harrod, SB | 1 |
| Hashimoto, K; Hirano, M; Kajihata, T; Kuroki, T; Nakahara, T; Ohta, E; Tsutsumi, T; Uchimura, H; Yamada, H; Yamanaka, M | 1 |
| Cadet, JL; Deng, X; Jayanthi, S | 1 |
| Blankenmeyer, TL; Brown, CA; Gudelsky, GA; Schaefer, TL; Vorhees, CV; Williams, MT | 1 |
| Hasegawa, T; He, J; Kim, HC; Kitaichi, K; Mamiya, T; Miyamoto, Y; Mizuno, M; Nabeshima, T; Nagai, T; Nakajima, A; Nitta, A; Saito, K; Seishima, M; Sekikawa, K; Seto, A; Tran, MH; Uchiyama, T; Yamada, K; Yamada, Y; Yoshimura, M | 1 |
| Dluzen, DE | 1 |
| Angulo, JA; Cadet, JL; Wang, J; Yu, J | 1 |
| Card, JP; Hastings, TG; LaVoie, MJ | 1 |
| Gasior, M; Goldberg, SR; Munzar, P; Witkin, JM | 1 |
| Fukami, G; Hashimoto, K; Iyo, M; Koike, K; Okamura, N; Shimizu, E | 1 |
| Fleckenstein, AE; Hanson, GR; Rau, KS | 1 |
| Carey, CL; Cherner, M; Gonzalez, R; Grant, I; Heaton, RK; Moore, DJ; Rippeth, JD; Schweinsburg, BC | 1 |
| Matuszewich, L; Yamamoto, BK | 1 |
| Achat-Mendes, C; Ali, SF; Itzhak, Y | 1 |
| Bae, SC; Chung, A; Hwang, J; Kim, DJ; Kim, SJ; Lyoo, IK; Renshaw, PF; Sung, YH; Yoo, J; Yoon, SJ | 1 |
| Camarasa, J; Chipana, C; Escubedo, E; Pérez-Sánchez, M; Pubill, D | 1 |
| Gold, MS; Hayes, RL; Kobeissy, FH; Liu, MC; Wang, KK; Warren, MW | 1 |
| D'Astous, M; Di Paolo, T; Dluzen, DE; Mickley, KR | 1 |
| Achat-Mendes, C; Anderson, KL; Itzhak, Y | 1 |
| Cho, SI; Chung, HS; Jang, CG; Lee, SK; Lee, SM; Lim, MA; Park, MJ | 1 |
| Barr, AM; Honer, WG; Lang, DJ; Lecomte, T; MacEwan, GW; Panenka, WJ; Thornton, AE | 1 |
| Ali, SF; Amato, A; Binienda, ZK; Przybyla, BD; Robinson, BL; Salem, N; Virmani, A | 1 |
| Ruha, AM; Yarema, MC | 1 |
| Fleckenstein, AE; Gibb, JW; Hanson, GR; Riddle, EL; Volz, TJ | 1 |
| Cadet, JL; Jayanthi, S; Krasnova, IN; Lyles, J | 1 |
| Fleckenstein, AE; Hanson, GR; Volz, TJ | 1 |
| Ali, SF; Sharma, HS; Sjöquist, PO | 1 |
| Cho, AK; Fairbanks, LA; Jorgensen, MJ; Laćan, G; Melega, WP; Morton, G; Pham, J; Way, BM | 1 |
| Ito, S; Kanazawa, H; Mori, T; Sawaguchi, T | 1 |
| Chang, C; Chen, CC; Hsu, YH; Yang, LC; Yen, CC; Zechariah, A | 1 |
| Chen, HI; Cherng, CG; Ho, MC; Jen, CJ; Ke, JJ; Kuo, YM; Tsai, CW; Tsai, YP; Yu, L | 1 |
| Kaneko, S; Nakagawa, T | 1 |
| Fukakusa, A; Koike, H; Mizoguchi, H; Nabeshima, T; Takuma, K; Yamada, K | 1 |
| Booze, RM; Ferris, MJ; Mactutus, CF | 1 |
| Camarasa, J; Chipana, C; Escubedo, E; Pubill, D; Torres, I | 1 |
| Kita, T; Kubo, K; Matsunari, Y; Nakashima, T; O'Hara, K; Saraya, T; Shimada, K; Wagner, GC | 1 |
| Ali, SF; Imam, SZ; Islam, F; Itzhak, Y; Slikker, W | 1 |
| Ali, SF; Miller, DB; O'Callaghan, JP | 1 |
| Cadet, JL; Deng, X; Huestis, MA; Krasnova, IN; Ladenheim, B; Moran, TH; Oyler, JM; Polettini, A | 1 |
| Chapman, DE; Hanson, GR; Keefe, KA; Kesner, RP | 1 |
| Callahan, BT; McCann, UD; Ricaurte, GA; Yuan, J | 1 |
| Callahan, BT; Cord, BJ; McCann, UD; Ricaurte, GA; Yuan, J | 1 |
| Bubula, N; Heller, A; Heller, B; Lew, R; Won, L | 1 |
| Fleckenstein, AE; Hanson, GR; Kokoshka, JM; Riddle, EL; Wilkins, DG | 1 |
| Cho, AK; Melega, WP | 1 |
41 review(s) available for methamphetamine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Possible repair mechanisms of renin-angiotensin system inhibitors, matrix metalloproteinase-9 inhibitors and protein hormones on methamphetamine-induced neurotoxicity.
Topics: Animals; Blood-Brain Barrier; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Methamphetamine; Neurotoxicity Syndromes; Prolactin; Renin-Angiotensin System | 2021 |
Methamphetamine, neurotransmitters and neurodevelopment.
Topics: Animals; Behavior, Animal; Central Nervous System; Central Nervous System Stimulants; Humans; Methamphetamine; Neurogenesis; Neurotoxicity Syndromes; Neurotransmitter Agents; Rats; Synaptic Transmission | 2021 |
Potential Effects of Nrf2 in Exercise Intervention of Neurotoxicity Caused by Methamphetamine Oxidative Stress.
Topics: Antioxidants; Exercise Therapy; Humans; Methamphetamine; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidative Stress | 2022 |
Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies.
Topics: Amphetamine-Related Disorders; Astrocytes; Central Nervous System Stimulants; Humans; Methamphetamine; Neurotoxicity Syndromes; Parkinson Disease | 2022 |
The Role of Non-coding RNAs in Methamphetamine-Induced Neurotoxicity.
Topics: Amphetamine; Behavior, Addictive; Humans; Methamphetamine; MicroRNAs; Neurotoxicity Syndromes | 2023 |
Overview of blood-brain barrier dysfunction in methamphetamine abuse.
Topics: Amphetamine-Related Disorders; Blood-Brain Barrier; Central Nervous System Stimulants; Humans; Methamphetamine; Neurotoxicity Syndromes | 2023 |
Antioxidant cascades confer neuroprotection in ethanol, morphine, and methamphetamine preconditioning.
Topics: Analgesics, Opioid; Animals; Antioxidants; Central Nervous System Depressants; Central Nervous System Stimulants; Ethanol; Humans; Methamphetamine; Morphine; Neuroprotection; Neurotoxicity Syndromes | 2019 |
Mephedrone and MDMA: A comparative review.
Topics: Brain; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes | 2020 |
TBHQ-Overview of Multiple Mechanisms against Oxidative Stress for Attenuating Methamphetamine-Induced Neurotoxicity.
Topics: Antioxidants; Humans; Hydroquinones; Methamphetamine; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidative Stress | 2020 |
The Role of α-Synuclein in Methamphetamine-Induced Neurotoxicity.
Topics: alpha-Synuclein; Animals; Central Nervous System Stimulants; Humans; Methamphetamine; Neurotoxicity Syndromes | 2021 |
Non-coding RNA: insights into the mechanism of methamphetamine neurotoxicity.
Topics: Animals; Humans; Methamphetamine; Neurotoxicity Syndromes; RNA, Untranslated | 2021 |
Neurotoxicity of methamphetamine: Main effects and mechanisms.
Topics: Animals; Brain; Central Nervous System Stimulants; Humans; Methamphetamine; Neurotoxicity Syndromes | 2021 |
Levo-tetrahydropalmatine: A new potential medication for methamphetamine addiction and neurotoxicity.
Topics: Animals; Berberine Alkaloids; Central Nervous System Stimulants; Dopamine Antagonists; Humans; Methamphetamine; Neurotoxicity Syndromes; Substance-Related Disorders | 2021 |
Converging dopaminergic neurotoxicity mechanisms of antipsychotics, methamphetamine and levodopa.
Topics: Antipsychotic Agents; Dopamine; Dopaminergic Neurons; Humans; Levodopa; Methamphetamine; Mitochondria; Neurotoxicity Syndromes; Oxidation-Reduction; Oxidative Stress; Synaptic Transmission | 2021 |
Molecular, Behavioral, and Physiological Consequences of Methamphetamine Neurotoxicity: Implications for Treatment.
Topics: Amphetamine-Related Disorders; Animals; Cognitive Dysfunction; Dopaminergic Neurons; Dose-Response Relationship, Drug; Humans; Methamphetamine; Neural Pathways; Neurotoxicity Syndromes; Serotonergic Neurons | 2017 |
Methamphetamine neurotoxicity, microglia, and neuroinflammation.
Topics: Animals; Central Nervous System Stimulants; Encephalitis; Humans; Methamphetamine; Microglia; Neurotoxicity Syndromes | 2018 |
Bath salts and polyconsumption: in search of drug-drug interactions.
Topics: Alkaloids; Animals; Cannabinoids; Central Nervous System Stimulants; Cocaine; Drug Interactions; Humans; Illicit Drugs; Methamphetamine; Mice; Neurotoxicity Syndromes; Polypharmacy; Rats; Substance-Related Disorders | 2019 |
Mechanisms of neurotoxicity and implications for neurological disorders.
Topics: Anti-HIV Agents; Central Nervous System Stimulants; Congresses as Topic; Hazardous Substances; Humans; Manganese; Methamphetamine; Nervous System Diseases; Neurotoxicity Syndromes; Neurotoxins; Parkinson Disease; Receptors, Dopamine; Risk Factors; Trace Elements | 2013 |
The role of dopamine receptors in the neurotoxicity of methamphetamine.
Topics: Animals; Dopamine Agents; Humans; Methamphetamine; Mice; Neurotoxicity Syndromes; Oxidative Stress; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2013 |
Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine.
Topics: Animals; Central Nervous System Stimulants; Dopamine; Hallucinogens; Humans; Methamphetamine; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Neurotoxicity Syndromes; Oxidative Stress; Serotonin | 2014 |
Melatonin Attenuates Methamphetamine-Induced Neurotoxicity.
Topics: Adult; Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Humans; Melatonin; Methamphetamine; Neurotoxicity Syndromes; Rats | 2016 |
Recent advances in methamphetamine neurotoxicity mechanisms and its molecular pathophysiology.
Topics: Animals; Brain; Dopamine; Endoplasmic Reticulum; Gene Expression; Humans; Methamphetamine; Neurotoxicity Syndromes | 2015 |
Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms.
Topics: Animals; Brain; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes | 2017 |
The Role of Oxidative Stress in Methamphetamine-induced Toxicity and Sources of Variation in the Design of Animal Studies.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Methamphetamine; Neurotoxicity Syndromes; Oxidative Stress | 2017 |
Mechanisms involved in the neurotoxic and cognitive effects of developmental methamphetamine exposure.
Topics: Animals; Animals, Newborn; Cognition; Female; Humans; Methamphetamine; Neurodevelopmental Disorders; Neurotoxicity Syndromes; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects | 2016 |
Neurotoxicity Induced by Mephedrone: An up-to-date Review.
Topics: Animals; Central Nervous System Stimulants; Databases, Bibliographic; Humans; Methamphetamine; Neurotoxicity Syndromes | 2017 |
Methamphetamine toxicity and messengers of death.
Topics: Animals; Blood-Brain Barrier; Body Temperature Regulation; Cell Death; Central Nervous System; Central Nervous System Stimulants; DNA Damage; Humans; Methamphetamine; Neurotoxicity Syndromes; Receptors, Dopamine; Substance-Related Disorders | 2009 |
Dopamine-induced behavioral changes and oxidative stress in methamphetamine-induced neurotoxicity.
Topics: Animals; Behavior; Brain; Central Nervous System Stimulants; Dopamine; Humans; Methamphetamine; Neurotoxicity Syndromes; Oxidative Stress | 2009 |
Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications.
Topics: Animals; Brain; Central Nervous System Stimulants; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Reactive Oxygen Species; Receptors, Nicotinic | 2009 |
Could sigma receptor ligands be a treatment for methamphetamine addiction?
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Humans; Ligands; Methamphetamine; Motor Activity; Neurotoxicity Syndromes; Receptors, sigma | 2010 |
Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis.
Topics: Animals; Apoptosis; Cytoprotection; Humans; Methamphetamine; Mice; Models, Biological; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Presynaptic Terminals; Rats; Signal Transduction | 2003 |
The methamphetamine experience: a NIDA partnership.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; National Institutes of Health (U.S.); Nerve Tissue Proteins; Neurotoxicity Syndromes; Serotonin; United States | 2004 |
The need for speed: an update on methamphetamine addiction.
Topics: Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Cognition Disorders; Cross-Sectional Studies; Disease Models, Animal; Humans; Methamphetamine; Neurotoxicity Syndromes; Psychoses, Substance-Induced | 2006 |
New insights into the mechanism of action of amphetamines.
Topics: Amphetamines; Animals; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Humans; Methamphetamine; Neurotoxicity Syndromes; Vesicular Monoamine Transport Proteins | 2007 |
Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms.
Topics: Amphetamines; Animals; Apoptosis; Central Nervous System Stimulants; Dopamine; Fever; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Oxidative Stress | 2007 |
Methamphetamine-induced alterations in monoamine transport: implications for neurotoxicity, neuroprotection and treatment.
Topics: Amphetamine-Related Disorders; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Methamphetamine; Neurodegenerative Diseases; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2007 |
Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: neuroprotective effects of a new antioxidant compound H-290/51.
Topics: Amphetamine-Related Disorders; Animals; Antioxidants; Blood-Brain Barrier; Central Nervous System Stimulants; Fever; Humans; Indoles; Methamphetamine; Morphine Dependence; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotransmitter Agents; Oxidative Stress; Reactive Oxygen Species; Substance Withdrawal Syndrome; Substance-Related Disorders | 2007 |
Interactions of HIV and methamphetamine: cellular and molecular mechanisms of toxicity potentiation.
Topics: Amphetamine-Related Disorders; Animals; Apoptosis; Central Nervous System Stimulants; Gene Expression Regulation, Viral; HIV Infections; Human Immunodeficiency Virus Proteins; Humans; Methamphetamine; Neurotoxicity Syndromes | 2007 |
Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy).
Topics: 5-Methoxytryptamine; Animals; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamine; Humans; Limbic System; Membrane Potentials; Mesencephalon; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Oocytes; Organ Culture Techniques; Raphe Nuclei; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Xenopus | 2008 |
Neurotoxic profiles of HIV, psychostimulant drugs of abuse, and their concerted effect on the brain: current status of dopamine system vulnerability in NeuroAIDS.
Topics: Animals; Brain; Cocaine; Dopamine; HIV; HIV Infections; Humans; Methamphetamine; Nervous System Diseases; Neural Pathways; Neurotoxicity Syndromes; Neurotoxins; Substance-Related Disorders | 2008 |
Patterns of methamphetamine abuse and their consequences.
Topics: Amphetamines; Central Nervous System Stimulants; Humans; Methamphetamine; Models, Chemical; Neurotoxicity Syndromes; Substance-Related Disorders | 2002 |
1 trial(s) available for methamphetamine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Neurocognitive performance of methamphetamine users discordant for history of marijuana exposure.
Topics: Adult; Amphetamine-Related Disorders; Brain; Cannabinoids; Cognition; Comorbidity; Drug Interactions; Female; Humans; Male; Marijuana Abuse; Methamphetamine; Middle Aged; Neuropsychological Tests; Neurotoxicity Syndromes; Psychometrics | 2004 |
135 other study(ies) available for methamphetamine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Effects of methamphetamine-induced neurotoxicity on striatal long-term potentiation.
Topics: Animals; Corpus Striatum; Dopamine; Long-Term Potentiation; Methamphetamine; Mice; Neurotoxicity Syndromes | 2022 |
Neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity.
Topics: Animals; Hippocampus; Long-Term Potentiation; Methamphetamine; Mice; Neuronal Plasticity; Neurotoxicity Syndromes | 2022 |
Icariside II Attenuates Methamphetamine-Induced Neurotoxicity and Behavioral Impairments via Activating the Keap1-Nrf2 Pathway.
Topics: Animals; Dopamine; Flavonoids; Kelch-Like ECH-Associated Protein 1; Methamphetamine; Mice; Neurotoxicity Syndromes; NF-E2-Related Factor 2 | 2022 |
Erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in CA1 area of hippocampus.
Topics: Animals; Apoptosis; Erythropoietin; Hippocampus; Male; Memory Disorders; Methamphetamine; Neuroinflammatory Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar; Spatial Memory | 2022 |
Bacopa Protects against Neurotoxicity Induced by MPP
Topics: 1-Methyl-4-phenylpyridinium; Bacopa; Catecholamines; Methamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Reactive Oxygen Species | 2022 |
Transfer of neuron-derived α-synuclein to astrocytes induces neuroinflammation and blood-brain barrier damage after methamphetamine exposure: Involving the regulation of nuclear receptor-associated protein 1.
Topics: alpha-Synuclein; Astrocytes; Blood-Brain Barrier; Central Nervous System Stimulants; Endothelial Cells; Evans Blue; Fluorescein; Glial Cell Line-Derived Neurotrophic Factor; Humans; Immunoglobulin G; Interleukin-6; Methamphetamine; Neuroinflammatory Diseases; Neurons; Neurotoxicity Syndromes; Occludin; Receptors, Cytoplasmic and Nuclear; Tumor Necrosis Factor-alpha | 2022 |
Protein kinase Cδ mediates methamphetamine-induced dopaminergic neurotoxicity in mice via activation of microsomal epoxide hydrolase.
Topics: Acetophenones; Animals; Benzopyrans; Dopaminergic Neurons; Epoxide Hydrolases; Fever; Gene Knockout Techniques; Locomotion; Methamphetamine; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Oxidative Stress; Protein Kinase C-delta | 2019 |
The effect of α-synuclein and Tau in methamphetamine induced neurotoxicity in vivo and in vitro.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Cell Line; Central Nervous System Stimulants; Gene Silencing; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Primary Cell Culture; RNA, Small Interfering; tau Proteins | 2020 |
Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats.
Topics: Animals; Apoptosis; Autophagy; Gene Expression; Luteolin; Male; Methamphetamine; Neurotoxicity Syndromes; Phosphatidylinositol 3-Kinases; Principal Component Analysis; Protective Agents; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2020 |
High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone.
Topics: Ammonia; Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Female; Glutamic Acid; Hot Temperature; Male; Methamphetamine; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Propiophenones; Signal Transduction; Substance-Related Disorders | 2020 |
Differential Responses of LINE-1 in the Dentate Gyrus, Striatum and Prefrontal Cortex to Chronic Neurotoxic Methamphetamine: A Study in Rat Brain.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Dentate Gyrus; Long Interspersed Nucleotide Elements; Male; Methamphetamine; Neurotoxicity Syndromes; Open Reading Frames; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2020 |
Alpha-Synuclein deficiency ameliorates chronic methamphetamine induced neurodegeneration in mice.
Topics: alpha-Synuclein; Animals; Autophagy; Axons; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Hippocampus; Lysosomes; Male; Methamphetamine; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Phosphorylation; Substantia Nigra; tau Proteins; Time Factors | 2020 |
TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.
Topics: Animals; Antioxidants; Hydroquinones; Male; Methamphetamine; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction | 2020 |
Role of alpha-synuclein phosphorylation at Serine 129 in methamphetamine-induced neurotoxicity in vitro and in vivo.
Topics: alpha-Synuclein; Animals; Cell Line; Central Nervous System Stimulants; Humans; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Phosphorylation; Protein Aggregation, Pathological; Serine | 2020 |
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure.
Topics: alpha-Synuclein; Animals; Astrocytes; Cell Line, Tumor; Central Nervous System Stimulants; Coculture Techniques; Cytokines; Exosomes; Hippocampus; Humans; Injections, Intraperitoneal; Male; Methamphetamine; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nuclear Receptor Subfamily 4, Group A, Member 2; Primary Cell Culture; Synucleinopathies | 2020 |
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Topics: Animals; Autophagy; Central Nervous System Stimulants; Down-Regulation; Enteritis; Feces; Gastrointestinal Microbiome; Male; Metabolomics; Methamphetamine; Mice, Inbred BALB C; Monoamine Oxidase; Myeloid Differentiation Factor 88; Neurotoxicity Syndromes; NF-kappa B p50 Subunit; Occludin; Toll-Like Receptor 4; Tyrosine 3-Monooxygenase; Up-Regulation | 2021 |
Inhibition of PLCβ1 signaling pathway regulates methamphetamine self-administration and neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Cell Line, Tumor; Cell Survival; Central Nervous System Stimulants; Gene Expression Regulation; Humans; Male; Methamphetamine; Motor Activity; Neurotoxicity Syndromes; Phospholipase C beta; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction | 2021 |
Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity.
Topics: Animals; Apoptosis; Curcuma; Curcumin; Humans; Methamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; PC12 Cells; Plant Extracts; Rats | 2021 |
Distinct dose-dependent effects of methamphetamine on real-time dopamine transmission in the rat nucleus accumbens and behaviors.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Motor Activity; Neurotoxicity Syndromes; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Synaptic Transmission | 2021 |
Dopaminergic Neuron-Specific Deletion of p53 Gene Attenuates Methamphetamine Neurotoxicity.
Topics: Animals; bcl-2-Associated X Protein; Benzothiazoles; Central Nervous System Stimulants; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Exploratory Behavior; Fever; Glial Fibrillary Acidic Protein; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurotoxicity Syndromes; rho GTP-Binding Proteins; Substantia Nigra; Toluene; Tumor Suppressor Protein p53; Tyrosine 3-Monooxygenase; Up-Regulation | 2017 |
Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice.
Topics: Animals; Apoptosis; Butadienes; Cells, Cultured; Corpus Striatum; Dopamine; Extracellular Signal-Regulated MAP Kinases; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Nitriles; Oxidative Stress; Piperidines; Protein Kinase C-delta; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; Rimonabant; Sulpiride | 2017 |
Mens Rea and Methamphetamine: High Time for a Modern Doctrine Acknowledging the Neuroscience of Addiction.
Topics: Aggression; Crime; Criminal Law; Humans; Liability, Legal; Methamphetamine; Neurosciences; Neurotoxicity Syndromes; Prohibitins; Substance-Related Disorders; Supreme Court Decisions; United States; Violence | 2017 |
Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity.
Topics: Acetylcysteine; Amphetamines; Apoptosis; Autophagy; Benzodioxoles; Cell Line; Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Humans; Methamphetamine; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Oxidative Stress; Pyrrolidines; Synthetic Cathinone | 2017 |
Recombinant AAV8-mediated intrastriatal gene delivery of CDNF protects rats against methamphetamine neurotoxicity.
Topics: Animals; Corpus Striatum; Dopamine; Fever; Gene Transfer Techniques; Genetic Therapy; Humans; Methamphetamine; Nerve Growth Factors; Neurons; Neurotoxicity Syndromes; PC12 Cells; Rats; Tyrosine 3-Monooxygenase | 2017 |
Assessing the role of dopamine in the differential neurotoxicity patterns of methamphetamine, mephedrone, methcathinone and 4-methylmethamphetamine.
Topics: Analysis of Variance; Animals; Body Temperature; Brain; Designer Drugs; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Synergism; Female; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroglia; Neurotoxicity Syndromes; Propiophenones; Tyrosine 3-Monooxygenase | 2018 |
Trace amine-associated receptor 1 regulation of methamphetamine-induced neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Body Temperature Regulation; Brain; Central Nervous System Stimulants; Disease Models, Animal; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxicity Syndromes; Receptors, G-Protein-Coupled; Time Factors; Tyrosine 3-Monooxygenase | 2017 |
Methamphetamine Augments Concurrent Astrocyte Mitochondrial Stress, Oxidative Burden, and Antioxidant Capacity: Tipping the Balance in HIV-Associated Neurodegeneration.
Topics: Antioxidants; Astrocytes; Cells, Cultured; Central Nervous System Stimulants; HIV Infections; Humans; Methamphetamine; Mitochondria; Neurons; Neurotoxicity Syndromes; Oxidative Stress | 2018 |
Protective and restorative effects of the traditional Chinese medicine Jitai tablet against methamphetamine-induced dopaminergic neurotoxicity.
Topics: Animals; Behavior, Animal; Dopamine; Drugs, Chinese Herbal; Humans; Male; Medicine, Chinese Traditional; Methamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Wistar; Receptors, Dopamine D2; Substantia Nigra; Tablets; Tyrosine 3-Monooxygenase | 2018 |
Lactulose attenuates METH-induced neurotoxicity by alleviating the impaired autophagy, stabilizing the perturbed antioxidant system and suppressing apoptosis in rat striatum.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Biomarkers; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Corpus Striatum; Lactulose; Liver; Male; Methamphetamine; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species | 2018 |
The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats.
Topics: Age Factors; Analysis of Variance; Animals; Brain; Central Nervous System Stimulants; Comet Assay; Disease Models, Animal; Dopamine; Glutamic Acid; Male; Methamphetamine; Microdialysis; Neurotoxicity Syndromes; Rats; Rats, Wistar; Serotonin; Synaptic Transmission | 2018 |
Dissociation between hypothermia and neurotoxicity caused by mephedrone and methcathinone in TPH2 knockout mice.
Topics: Animals; Female; Hypothermia; Illicit Drugs; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Neurotoxicity Syndromes; Propiophenones; Tryptophan Hydroxylase | 2019 |
mGluR5 upregulation and the effects of repeated methamphetamine administration and withdrawal on the rewarding efficacy of ketamine and social interaction.
Topics: Animals; Dopamine; Excitatory Amino Acid Transporter 3; Hippocampus; Homer Scaffolding Proteins; Interpersonal Relations; Ketamine; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Nucleus Accumbens; Receptors, Kainic Acid; Reward; Up-Regulation | 2018 |
Krill oil protects PC12 cells against methamphetamine-induced neurotoxicity by inhibiting apoptotic response and oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Dietary Fats, Unsaturated; Dietary Supplements; Euphausiacea; Glutathione; Malondialdehyde; Membrane Potential, Mitochondrial; Methamphetamine; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2018 |
Sex differences in memory and intracellular signaling after methamphetamine binge treatment.
Topics: Animals; Caudate Nucleus; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Male; Memory; Methamphetamine; Neurotoxicity Syndromes; Nucleus Accumbens; Ovariectomy; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sex Factors; Substantia Nigra; Tyrosine 3-Monooxygenase | 2019 |
Causal connection between methamphetamine and neurotoxicity not established.
Topics: Central Nervous System Stimulants; Humans; Infant, Newborn; Methamphetamine; Neurotoxicity Syndromes | 2019 |
Effect of methamphetamine on rat primary midbrain cells; mitochondrial biogenesis as a compensatory response.
Topics: alpha-Synuclein; Animals; Cell Death; Female; Mesencephalon; Methamphetamine; Mitochondria; Neurites; Neurons; Neurotoxicity Syndromes; Organelle Biogenesis; Rats, Wistar | 2019 |
Response to "Causal connection between methamphetamine and neurotoxicity not established".
Topics: Corpus Striatum; Humans; Infant, Newborn; Methamphetamine; Neurotoxicity Syndromes | 2019 |
The role of chaperone-mediated autophagy in neurotoxicity induced by alpha-synuclein after methamphetamine exposure.
Topics: alpha-Synuclein; Animals; Cell Line; Central Nervous System Stimulants; Chaperone-Mediated Autophagy; Down-Regulation; HSC70 Heat-Shock Proteins; Humans; Lysosomal-Associated Membrane Protein 2; Methamphetamine; Neurons; Neurotoxicity Syndromes; Protective Factors; Rats; RNA, Small Interfering | 2019 |
Glial reactivity in resistance to methamphetamine-induced neurotoxicity.
Topics: Amphetamine-Related Disorders; Animals; Astrocytes; CD11b Antigen; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Fever; Gene Expression; Glial Fibrillary Acidic Protein; Male; Methamphetamine; Microglia; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley | 2013 |
Chronic wheel running reduces maladaptive patterns of methamphetamine intake: regulation by attenuation of methamphetamine-induced neuronal nitric oxide synthase.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Caspase 3; Cell Proliferation; Central Nervous System Stimulants; Disease Models, Animal; Hippocampus; Ki-67 Antigen; Male; Methamphetamine; Neural Stem Cells; Neurons; Neurotoxicity Syndromes; Nitric Oxide Synthase; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reward; Running; Self Administration; Time Factors | 2014 |
Phasic-like stimulation of the medial forebrain bundle augments striatal gene expression despite methamphetamine-induced partial dopamine denervation.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Corpus Striatum; Cytoskeletal Proteins; Denervation; Dopamine; Dopaminergic Neurons; Early Growth Response Protein 1; Electric Stimulation; Gene Expression; Genes, Immediate-Early; Male; Medial Forebrain Bundle; Methamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tachykinins | 2013 |
The role of the neuropeptide somatostatin on methamphetamine and glutamate-induced neurotoxicity in the striatum of mice.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Fluoresceins; Glutamic Acid; Male; Methamphetamine; Mice; Mice, Inbred ICR; Microinjections; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Octreotide; Somatostatin; Tyrosine; Tyrosine 3-Monooxygenase | 2013 |
σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation.
Topics: Animals; Benzothiazoles; Body Temperature; Corpus Striatum; Dopamine; Dopamine Agents; Fever; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Oxalates; Piperazines; Piperidines; Receptors, sigma | 2013 |
Hypothesizing that designer drugs containing cathinones ("bath salts") have profound neuro-inflammatory effects and dangerous neurotoxic response following human consumption.
Topics: Alkaloids; Benzodioxoles; Designer Drugs; Dopamine Plasma Membrane Transport Proteins; Humans; Methamphetamine; Models, Biological; Neurogenic Inflammation; Neurotoxicity Syndromes; Pyrrolidines; Synthetic Cathinone | 2013 |
9-Cis retinoic acid protects against methamphetamine-induced neurotoxicity in nigrostriatal dopamine neurons.
Topics: Alitretinoin; Animals; Bone Morphogenetic Protein 7; Carrier Proteins; Cells, Cultured; Corpus Striatum; Dopaminergic Neurons; Male; Methamphetamine; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Nuclear Receptor Subfamily 4, Group A, Member 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tretinoin; Tyrosine 3-Monooxygenase | 2014 |
Effects of combined treatment with mephedrone and methamphetamine or 3,4-methylenedioxymethamphetamine on serotonin nerve endings of the hippocampus.
Topics: Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Designer Drugs; Female; Hippocampus; Methamphetamine; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Neurotoxicity Syndromes; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase | 2014 |
Assessment of therapeutic potential of amantadine in methamphetamine induced neurotoxicity.
Topics: Amantadine; Animals; Behavior, Animal; Catalepsy; Dopamine; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mitochondrial Diseases; Neostriatum; Neurotoxicity Syndromes; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Serotonin; Superoxide Dismutase | 2013 |
7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Dopamine Plasma Membrane Transport Proteins; Flavones; Flavonoids; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Motor Activity; Neostriatum; Neurotoxicity Syndromes; Receptor, trkB | 2014 |
Protective effect of geranylgeranylacetone against methamphetamine-induced neurotoxicity in rat pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Apoptosis; Caspases; Cell Line, Tumor; Diterpenes; HSP70 Heat-Shock Proteins; Methamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Pheochromocytoma; Rats; Thioredoxins; Tyrosine 3-Monooxygenase | 2013 |
A single neurotoxic dose of methamphetamine induces a long-lasting depressive-like behaviour in mice.
Topics: Animals; Astrocytes; Corpus Striatum; Depressive Disorder; Dopamine; Escape Reaction; Frontal Lobe; Locomotion; Male; Maze Learning; Memory; Methamphetamine; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Serotonin; Swimming; Time Factors | 2014 |
Methamphetamine-induced neurotoxicity disrupts pharmacologically evoked dopamine transients in the dorsomedial and dorsolateral striatum.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Male; Methamphetamine; Neurotoxicity Syndromes; Presynaptic Terminals; Rats, Sprague-Dawley; Synaptic Transmission | 2014 |
Repeated doses of methylone, a new drug of abuse, induce changes in serotonin and dopamine systems in the mouse.
Topics: Animals; CA1 Region, Hippocampal; Cell Survival; Central Nervous System Stimulants; Depression; Dopamine; Dose-Response Relationship, Drug; Fever; Gliosis; Hippocampus; Male; Methamphetamine; Mice; Neostriatum; Neurons; Neurotoxicity Syndromes; Prefrontal Cortex; Serotonin; Swimming; Weight Loss | 2014 |
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors.
Topics: Animals; Arachidonic Acids; Benzamides; Benzodioxoles; Cannabinoid Receptor Modulators; Carbamates; Central Nervous System Stimulants; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Glycerides; Male; Methamphetamine; Mice, Inbred C57BL; Neostriatum; Neurotoxicity Syndromes; Piperidines; Polyunsaturated Alkamides; Random Allocation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2014 |
Single and binge methamphetamine administrations have different effects on the levels of dopamine D2 autoreceptor and dopamine transporter in rat striatum.
Topics: Animals; Autoreceptors; Axonal Transport; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fever; Male; Methamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Synaptosomes | 2014 |
S-Nitrosylating protein disulphide isomerase mediates α-synuclein aggregation caused by methamphetamine exposure in PC12 cells.
Topics: alpha-Synuclein; Animals; Apoptosis; Cell Survival; Central Nervous System Stimulants; Enzyme Inhibitors; Gene Knockdown Techniques; Methamphetamine; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; PC12 Cells; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Rats; RNA Interference; Time Factors; Transfection | 2014 |
Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis.
Topics: Animals; Annexin A5; Apoptosis; Caspase 3; Corpus Striatum; Cytochromes c; Cytoplasm; Dopaminergic Neurons; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Silencing; In Situ Nick-End Labeling; Insulin-Like Growth Factor Binding Protein 5; Male; Methamphetamine; Mitochondria; Neurotoxicity Syndromes; PC12 Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2014 |
Serotonergic impairment and memory deficits in adolescent rats after binge exposure of methylone.
Topics: Animals; Corpus Striatum; Designer Drugs; Dopamine Plasma Membrane Transport Proteins; Frontal Lobe; Gliosis; Hippocampus; Male; Maze Learning; Memory Disorders; Methamphetamine; Neurotoxicity Syndromes; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Serotonergic Neurons; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2014 |
Characterization of binge-dosed methamphetamine-induced neurotoxicity and neuroinflammation.
Topics: Animals; Biogenic Monoamines; Body Temperature; Calcium-Binding Proteins; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Electrochemical Techniques; Encephalitis; Glial Fibrillary Acidic Protein; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microfilament Proteins; Motor Activity; Neurotoxicity Syndromes; Time Factors; Tyrosine 3-Monooxygenase | 2015 |
Methamphetamine oxidative stress, neurotoxicity, and functional deficits are modulated by nuclear factor-E2-related factor 2.
Topics: Animals; Apoptosis; Behavior, Animal; Blotting, Western; Cell Proliferation; Cells, Cultured; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Fever; Glial Fibrillary Acidic Protein; Humans; Immunoenzyme Techniques; Methamphetamine; Mice; Mice, Knockout; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine 3-Monooxygenase | 2015 |
Methamphetamine-, d-Amphetamine-, and p-Chloroamphetamine-Induced Neurotoxicity Differentially Effect Impulsive Responding on the Stop-Signal Task in Rats.
Topics: Animals; Body Temperature; Brain; Central Nervous System Stimulants; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Impulsive Behavior; Male; Methamphetamine; Motor Activity; Neuropsychological Tests; Neurotoxicity Syndromes; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2016 |
Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice.
Topics: Animals; Body Temperature; Cell Count; Corpus Striatum; Dopaminergic Neurons; Locomotion; Male; Methamphetamine; Mice; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Peptide Fragments; Rotarod Performance Test; Tetanus Toxin; Tyrosine 3-Monooxygenase | 2016 |
Vascular-directed responses of microglia produced by methamphetamine exposure: indirect evidence that microglia are involved in vascular repair?
Topics: Animals; Antigens, Surface; Blood Vessels; Calcium-Binding Proteins; CD11b Antigen; Central Nervous System Stimulants; Male; Membrane Glycoproteins; Methamphetamine; Microfilament Proteins; Microglia; Nerve Degeneration; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley | 2016 |
Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Caffeine; Discrimination, Psychological; Dopamine; Fever; Hypothermia; Illicit Drugs; Locomotion; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Reflex, Startle; Serotonin | 2016 |
Chronic Methamphetamine Effects on Brain Structure and Function in Rats.
Topics: Animals; Brain; Chronic Disease; Fluorodeoxyglucose F18; Male; Methamphetamine; Neurotoxicity Syndromes; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Substance-Related Disorders | 2016 |
PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice.
Topics: Animals; Apoptosis; Corpus Striatum; Cytosol; Dopamine; Membrane Potential, Mitochondrial; Methamphetamine; Mice, Knockout; Mitochondria; Neurotoxicity Syndromes; Protein Kinase C-delta; Stress, Physiological | 2016 |
dl-3-n-Butylphthalide attenuation of methamphetamine-induced neurotoxicity in SH-SY5Y neuroblastoma cells.
Topics: Benzofurans; Cell Line, Tumor; Humans; Methamphetamine; Neuroblastoma; Neurotoxicity Syndromes; Reactive Oxygen Species; Signal Transduction | 2016 |
Dissecting the Influence of Two Structural Substituents on the Differential Neurotoxic Effects of Acute Methamphetamine and Mephedrone Treatment on Dopamine Nerve Endings with the Use of 4-Methylmethamphetamine and Methcathinone.
Topics: Animals; Central Nervous System Stimulants; Dopaminergic Neurons; Dose-Response Relationship, Drug; Illicit Drugs; Methamphetamine; Mice; Nerve Endings; Neurotoxicity Syndromes; Propiophenones | 2017 |
Effect of +-methamphetamine on path integration learning, novel object recognition, and neurotoxicity in rats.
Topics: Animals; Biogenic Monoamines; Body Temperature; Central Nervous System Stimulants; Corticosterone; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Learning; Male; Maze Learning; Methamphetamine; Motor Activity; Neurotoxicity Syndromes; Organ Size; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Stereoisomerism; Stereotyped Behavior; Swimming | 2008 |
Relationship between methamphetamine exposure and matrix metalloproteinase 9 expression.
Topics: Animals; Brain; Corpus Striatum; Dopamine; Dopamine Agents; Gene Deletion; Gene Expression Regulation, Enzymologic; Immunoenzyme Techniques; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 9; Methamphetamine; Mice; Mice, Knockout; Neurotoxicity Syndromes; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2008 |
Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity.
Topics: Animals; Clorgyline; Cytosol; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Microglia; Monoamine Oxidase Inhibitors; Neurons; Neurotoxicity Syndromes; Nucleus Accumbens; Plant Lectins; Reserpine; Ribosome Inactivating Proteins; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
Protective effects of isoliquiritigenin against methamphetamine-induced neurotoxicity in mice.
Topics: Animals; Chalcones; Corpus Striatum; Cytoprotection; Dopamine Plasma Membrane Transport Proteins; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroglia; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase | 2009 |
Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity.
Topics: 5,7-Dihydroxytryptamine; Animals; Area Under Curve; Benzylamines; Brain; Central Nervous System Stimulants; Disease Models, Animal; Female; Gene Expression; Hallucinogens; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Neurotransmitter Uptake Inhibitors; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Time Factors; Vesicular Monoamine Transport Proteins | 2010 |
Relationships among gender, age, time, and temperature in methamphetamine-induced striatal dopaminergic neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Sex Factors; Time Factors | 2010 |
Methamphetamine neurotoxicity increases brain expression and alters behavioral functions of CB₁ cannabinoid receptors.
Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Benzoxazines; Brain; CA1 Region, Hippocampal; Cannabinoid Receptor Agonists; Caudate Nucleus; Central Nervous System Stimulants; Disease Models, Animal; Exploratory Behavior; Male; Memory; Methamphetamine; Morpholines; Motor Activity; Naphthalenes; Neurotoxicity Syndromes; Prefrontal Cortex; Putamen; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Reflex, Startle; Up-Regulation | 2010 |
Red wine but not ethanol at low doses can protect against the toxicity of methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Central Nervous System Depressants; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Ethanol; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Wine | 2010 |
Dopamine is not essential for the development of methamphetamine-induced neurotoxicity.
Topics: Adrenergic Agents; alpha-Methyltyrosine; Amphetamine-Related Disorders; Animals; Body Temperature; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Functional Laterality; Male; Methamphetamine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Synaptic Transmission | 2010 |
Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine.
Topics: Alcohol Drinking; Amidohydrolases; Animals; Arachidonic Acids; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocannabinoids; Glycerides; Limbic System; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Neurotoxicity Syndromes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1 | 2010 |
The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum.
Topics: Animals; Biogenic Monoamines; Blotting, Western; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Fenclonine; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Neurotoxicity Syndromes; Reactive Nitrogen Species; Reactive Oxygen Species; Serotonin; Serotonin Agents; Tryptophan Hydroxylase | 2010 |
A harmless high?
Topics: Adolescent; Central Nervous System Stimulants; Designer Drugs; Female; Humans; Methamphetamine; Neurotoxicity Syndromes | 2010 |
Dopaminergic neuronal injury in the adult rat brain following neonatal exposure to lipopolysaccharide and the silent neurotoxicity.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Central Nervous System Stimulants; Cytokines; Dopamine; Electron Transport Complex I; Female; Forelimb; Immunohistochemistry; Lipopolysaccharides; Methamphetamine; Motor Activity; Motor Skills; Neurons; Neurotoxicity Syndromes; Physical Stimulation; Pregnancy; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Vibrissae | 2011 |
Expression of heat shock protein (HSP 72 kDa) during acute methamphetamine intoxication depends on brain hyperthermia: neurotoxicity or neuroprotection?
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Central Nervous System Stimulants; Data Interpretation, Statistical; Fever; Glial Fibrillary Acidic Protein; HSP72 Heat-Shock Proteins; Immunohistochemistry; Male; Methamphetamine; Microscopy, Electron; Neurotoxicity Syndromes; Rats; Rats, Long-Evans | 2011 |
Sex differences in methamphetamine toxicity in mice: effect on brain dopamine signaling pathways.
Topics: Animals; Brain; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Male; Methamphetamine; Mice; Neural Pathways; Neurotoxicity Syndromes; Protein Binding; Sex Characteristics; Signal Transduction; Tetrabenazine; Vesicular Monoamine Transport Proteins | 2011 |
Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA.
Topics: Analysis of Variance; Animals; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Immunohistochemistry; Methamphetamine; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Receptors, Dopamine D2; Tyrosine 3-Monooxygenase | 2011 |
Synthesis and neurotoxicity profile of 2,4,5-trihydroxymethamphetamine and its 6-(N-acetylcystein-S-yl) conjugate.
Topics: Acetylcysteine; Adrenergic Uptake Inhibitors; Animals; Brain; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Serotonin | 2011 |
Methamphetamine neurotoxicity decreases phasic, but not tonic, dopaminergic signaling in the rat striatum.
Topics: Algorithms; Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Electric Stimulation; Electrophysiological Phenomena; Extracellular Space; Kinetics; Male; Methamphetamine; Microelectrodes; Neurons; Neurotoxicity Syndromes; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Signal Transduction; Sympathectomy, Chemical; Sympatholytics | 2011 |
Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Basal Ganglia; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Isothiocyanates; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Microglia; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Sulfoxides; Thiocyanates | 2012 |
Methods in drug abuse models: comparison of different models of methamphetamine paradigms.
Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Methamphetamine; Models, Animal; Neurotoxicity Syndromes; Rats | 2012 |
The effects of low-dose methamphetamine pretreatment on endoplasmic reticulum stress and methamphetamine neurotoxicity in the rat midbrain.
Topics: Animals; Blotting, Western; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Immunohistochemistry; Injections, Intraperitoneal; Male; Mesencephalon; Methamphetamine; Neurotoxicity Syndromes; Rats; Rats, Wistar; RNA, Messenger | 2012 |
Protective effect of sauchinone on methamphetamine-induced neurotoxicity in mice.
Topics: Animals; Benzopyrans; Dioxoles; Dose-Response Relationship, Drug; Lignans; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase Type II | 2012 |
Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens.
Topics: Animals; Brain Waves; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Interneurons; Male; Methamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Nucleus Accumbens; Piperidines; Psychomotor Performance; Psychotic Disorders; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Rimonabant | 2012 |
Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity.
Topics: Animals; Cell Line, Tumor; Central Nervous System Stimulants; Female; Hippocampus; Humans; Macaca mulatta; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Protein Disulfide-Isomerases; Substance-Related Disorders | 2012 |
Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.
Topics: Animals; Benzoxazoles; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Drug Synergism; Fever; Guanidines; Male; Methamphetamine; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Piperazines; Random Allocation; Receptors, sigma; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2013 |
The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice.
Topics: Analysis of Variance; Animals; Avoidance Learning; Benzothiazoles; Body Temperature; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Memory Disorders; Methamphetamine; Mice; Neurotoxicity Syndromes; Neurotransmitter Agents; Piperazines; Protein Binding; Receptors, sigma; Recognition, Psychology; Tritium | 2013 |
Disruption of subcellular Arc/Arg 3.1 mRNA expression in striatal efferent neurons following partial monoamine loss induced by methamphetamine.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Cytoskeletal Proteins; Dopamine; Gene Expression Regulation; In Situ Hybridization, Fluorescence; Male; Methamphetamine; Nerve Tissue Proteins; Neurons, Efferent; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 2012 |
Peripheral ammonia as a mediator of methamphetamine neurotoxicity.
Topics: Alanine Transaminase; Ammonia; Analysis of Variance; Animals; Aspartate Aminotransferases; Benzodiazepines; Biogenic Monoamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Fever; Gene Expression Regulation; Lactulose; Liver Diseases; Male; Mass Spectrometry; Methamphetamine; Microdialysis; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Expression and activity of nitric oxide synthase isoforms in methamphetamine-induced striatal dopamine toxicity.
Topics: Animals; Corpus Striatum; Dopamine; Enzyme Induction; In Situ Hybridization; Interneurons; Isoenzymes; Male; Methamphetamine; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley | 2013 |
Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity.
Topics: Analysis of Variance; Animals; Body Temperature; Chymotrypsin; Corpus Striatum; Dependovirus; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Methamphetamine; Neurotoxicity Syndromes; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synaptosomes; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases | 2013 |
Methamphetamine-induced dopaminergic neurotoxicity in mice: long-lasting sensitization to the locomotor stimulation and desensitization to the rewarding effects of methamphetamine.
Topics: Animals; Biomarkers; Central Nervous System Stimulants; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Male; Methamphetamine; Mice; Motor Activity; Neurotoxicity Syndromes; Reward; Stimulation, Chemical; Time Factors | 2002 |
Obesity exacerbates chemically induced neurodegeneration.
Topics: Animals; Astrocytes; Brain; Disease Models, Animal; Dopamine; Female; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Ion Channels; Kainic Acid; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Obese; Microtubule-Associated Proteins; Mitochondrial Proteins; Neostriatum; Neurodegenerative Diseases; Neurons; Neurotoxicity Syndromes; Neurotoxins; Obesity; Presynaptic Terminals; Proteins; Uncoupling Protein 2 | 2002 |
The effect of neurotoxic doses of methamphetamine on methamphetamine-conditioned place preference in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Body Weight; Brain Chemistry; Central Nervous System Stimulants; Conditioning, Operant; Dopamine; Female; Hydroxyindoleacetic Acid; Male; Methamphetamine; Neostriatum; Neurotoxicity Syndromes; Nucleus Accumbens; Prefrontal Cortex; Rats; Reward; Serotonin; Sex Characteristics | 2003 |
Effect of the neurotoxic dose of methamphetamine on gene expression of parkin and Pael-receptors in rat striatum.
Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Gene Expression; Genes, fos; Haloperidol; Kinetics; Ligases; Male; Methamphetamine; Neostriatum; Neurotoxicity Syndromes; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ubiquitin-Protein Ligases | 2003 |
Long-term effects of neonatal methamphetamine exposure in rats on spatial learning in the Barnes maze and on cliff avoidance, corticosterone release, and neurotoxicity in adulthood.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Appetite; Avoidance Learning; Body Weight; Central Nervous System Stimulants; Corticosterone; Dopamine; Female; Male; Maze Learning; Memory; Methamphetamine; Neurotoxicity Syndromes; Organ Size; Pituitary Gland; Rats; Rats, Sprague-Dawley; Reflex, Startle; Serotonin; Space Perception; Swimming | 2003 |
Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity.
Topics: Animals; Antigens, CD; Corpus Striatum; Discrimination Learning; Disease Models, Animal; Dopamine; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Microinjections; Motor Activity; Neurotoxicity Syndromes; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Reward; RNA, Messenger; Spatial Behavior; Substance-Related Disorders; Tumor Necrosis Factor-alpha | 2004 |
The effect of gender and the neurotrophin, BDNF, upon methamphetamine-induced neurotoxicity of the nigrostriatal dopaminergic system in mice.
Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Female; Humans; Male; Methamphetamine; Mice; Mice, Transgenic; Mutation; Neurotoxicity Syndromes; Sex Factors; Structure-Activity Relationship; Substantia Nigra | 2004 |
Histological evidence supporting a role for the striatal neurokinin-1 receptor in methamphetamine-induced neurotoxicity in the mouse brain.
Topics: Androstanes; Animals; Benzimidazoles; Brain; Cell Count; Corpus Striatum; Drug Interactions; Fluoresceins; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Methamphetamine; Mice; Nerve Degeneration; Neurokinin-1 Receptor Antagonists; Neurotoxicity Syndromes; Organic Chemicals; Receptors, Neurokinin-1; Tyrosine 3-Monooxygenase | 2004 |
Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity.
Topics: Animals; Axons; Brain; Cell Count; Cell Size; Corpus Striatum; Disease Progression; Dopamine; Hypothermia, Induced; Male; Methamphetamine; Microglia; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley | 2004 |
Chlormethiazole potentiates the discriminative stimulus effects of methamphetamine in rats.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Chlormethiazole; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; GABA Modulators; Generalization, Psychological; Male; Methamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Seizures | 2004 |
Effect of antioxidant N-acetyl-L-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine.
Topics: Acetylcysteine; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Free Radical Scavengers; Male; Methamphetamine; Neurotoxicity Syndromes; Rats; Time Factors | 2004 |
Effects of chronic stress on methamphetamine-induced dopamine depletions in the striatum.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Male; Methamphetamine; Neostriatum; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 2004 |
Differential effects of amphetamines-induced neurotoxicity on appetitive and aversive Pavlovian conditioning in mice.
Topics: Amphetamines; Animals; Antimanic Agents; Appetitive Behavior; Avoidance Learning; Central Nervous System Stimulants; Conditioning, Classical; Dopamine; Fenfluramine; Hallucinogens; Lithium Chloride; Male; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Neurotoxicity Syndromes; Receptors, Serotonin; Reinforcement, Psychology; Reward; Serotonin | 2005 |
Increased white matter hyperintensities in male methamphetamine abusers.
Topics: Adult; Amphetamine-Related Disorders; Brain; Cerebral Ventricles; Dementia, Vascular; Demyelinating Diseases; Dose-Response Relationship, Drug; Humans; Korea; Magnetic Resonance Imaging; Male; Methamphetamine; Midline Thalamic Nuclei; Neurotoxicity Syndromes; Reference Values; Risk Factors; Statistics as Topic | 2006 |
Methyllycaconitine prevents methamphetamine-induced effects in mouse striatum: involvement of alpha7 nicotinic receptors.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antioxidants; Blotting, Western; Body Temperature; Body Weight; Calcium; Cell Membrane; Central Nervous System Stimulants; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Immunohistochemistry; Isoquinolines; Male; Methamphetamine; Mice; Microglia; Motor Activity; Neostriatum; Neurotoxicity Syndromes; Nicotinic Antagonists; Radioligand Assay; Reactive Oxygen Species; Receptors, Nicotinic; Synaptic Vesicles; Synaptosomes; Tyrosine 3-Monooxygenase | 2005 |
Concurrent calpain and caspase-3 mediated proteolysis of alpha II-spectrin and tau in rat brain after methamphetamine exposure: a similar profile to traumatic brain injury.
Topics: Animals; Blotting, Western; Brain; Brain Injuries; Calpain; Caspase 3; Caspases; Cysteine Endopeptidases; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Male; Methamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Spectrin; tau Proteins | 2005 |
Differential protective properties of estradiol and tamoxifen against methamphetamine-induced nigrostriatal dopaminergic toxicity in mice.
Topics: Animals; Autoradiography; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalins; Estradiol; Estrogen Antagonists; In Situ Hybridization; Methamphetamine; Mice; Neurotoxicity Syndromes; Protein Precursors; Substantia Nigra; Tamoxifen; Vesicular Monoamine Transport Proteins | 2005 |
Impairment in consolidation of learned place preference following dopaminergic neurotoxicity in mice is ameliorated by N-acetylcysteine but not D1 and D2 dopamine receptor agonists.
Topics: Acetylcysteine; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione; Learning Disabilities; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase | 2007 |
Effect of alpha-tocopherol and deferoxamine on methamphetamine-induced neurotoxicity.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Biogenic Monoamines; Body Temperature; Corpus Striatum; Deferoxamine; Drug Administration Schedule; Drug Interactions; Glutathione; Lipid Peroxidation; Male; Methamphetamine; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Effects of L-carnitine pretreatment in methamphetamine and 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Antihypertensive Agents; Carnitine; Dopamine Agents; Male; Methamphetamine; Neurotoxicity Syndromes; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2006 |
Pharmacologic treatment of acute pediatric methamphetamine toxicity.
Topics: Benzodiazepines; Central Nervous System Depressants; Central Nervous System Stimulants; Child; Child, Preschool; Haloperidol; Humans; Infant; Methamphetamine; Neurotoxicity Syndromes; Retrospective Studies | 2006 |
Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles.
Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain; Brain Chemistry; Central Nervous System Stimulants; Chlorocebus aethiops; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Neurotoxicity Syndromes; Protein Binding; Raclopride; Social Behavior; Tritium | 2008 |
Tamoxifen protects male mice nigrostriatal dopamine against methamphetamine-induced toxicity.
Topics: Animals; Body Temperature; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Enkephalins; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neurotoxicity Syndromes; Protein Precursors; Selective Estrogen Receptor Modulators; Substantia Nigra; Tamoxifen; Vesicular Monoamine Transport Proteins | 2007 |
Differential effects of the ascorbyl and tocopheryl derivative on the methamphetamine-induced toxic behavior and toxicity.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Central Nervous System Stimulants; Dopamine; Electron Spin Resonance Spectroscopy; Free Radicals; Iron-Binding Proteins; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Molecular Structure; Morphine; Neurotoxicity Syndromes; Self-Injurious Behavior | 2007 |
Neuronal dysfunction of a long projecting multisynaptic pathway in response to methamphetamine using manganese-enhanced MRI.
Topics: Animals; Cations, Divalent; Central Nervous System Stimulants; Contrast Media; Corpus Striatum; Habenula; Image Enhancement; Magnetic Resonance Imaging; Male; Manganese; Methamphetamine; Neural Pathways; Neurons; Neurotoxicity Syndromes; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Synapses; Ventral Tegmental Area | 2008 |
Mutual enhancement of central neurotoxicity induced by ketamine followed by methamphetamine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Dissociative; Animals; Benzazepines; Body Temperature; Central Nervous System Stimulants; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Excitatory Amino Acid Antagonists; Glucose Transporter Type 1; Glutamates; Injections, Intraventricular; Ketamine; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Postural Balance; Receptors, Dopamine D1; Serotonin | 2008 |
Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity.
Topics: Animals; Corpus Striatum; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Neurotoxicity Syndromes; Nucleus Accumbens; Receptor, PAR-1; Tissue Plasminogen Activator; Tyrosine 3-Monooxygenase | 2008 |
Methamphetamine-induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling.
Topics: Animals; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; CX3C Chemokine Receptor 1; Disease Models, Animal; Dopamine; Green Fluorescent Proteins; Lectins; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurotoxicity Syndromes; Receptors, Chemokine; Signal Transduction; Time Factors | 2008 |
Memantine protects against amphetamine derivatives-induced neurotoxic damage in rodents.
Topics: Animals; Benzamides; Body Temperature; Bridged Bicyclo Compounds; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Excitatory Amino Acid Antagonists; Hallucinogens; Hippocampus; Male; Memantine; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Nicotinic; Serotonin Plasma Membrane Transport Proteins | 2008 |
Methamphetamine-induced striatal dopamine release, behavior changes and neurotoxicity in BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Behavior, Animal; Body Temperature; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Homovanillic Acid; Hydroxybenzoates; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Neurotoxicity Syndromes; Salicylic Acid; Self-Injurious Behavior; Species Specificity | 2000 |
Prevention of dopaminergic neurotoxicity by targeting nitric oxide and peroxynitrite: implications for the prevention of methamphetamine-induced neurotoxic damage.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic N-Oxides; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Electrochemistry; Free Radical Scavengers; Homovanillic Acid; Imidazoles; Indazoles; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Models, Biological; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Peroxynitrous Acid; Tyrosine | 2000 |
Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Area Under Curve; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Models, Biological; Neurotoxicity Syndromes; Sex Factors; Time Factors | 2000 |
Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6.
Topics: Amphetamine; Animals; Benzodiazepines; Carrier Proteins; Chromatography, High Pressure Liquid; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; In Situ Nick-End Labeling; Interleukin-6; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitochondria; Mutation; Nerve Tissue Proteins; Neurotoxicity Syndromes; Serotonin Plasma Membrane Transport Proteins; Temperature | 2000 |
Long-term changes in basal ganglia function after a neurotoxic regimen of methamphetamine.
Topics: Animals; Basal Ganglia; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Electron Transport Complex IV; Gene Expression Regulation; In Situ Hybridization; Male; Methamphetamine; Neural Pathways; Neuropeptides; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Serial Learning; Substance P; Substantia Nigra | 2001 |
Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Body Temperature; Brain Chemistry; Cytoplasm; Dopamine; Dopamine Uptake Inhibitors; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Reserpine; Sympatholytics | 2001 |
Inhibitors of Na(+)/H(+) and Na(+)/Ca(2+) exchange potentiate methamphetamine-induced dopamine neurotoxicity: possible role of ionic dysregulation in methamphetamine neurotoxicity.
Topics: Amiloride; Animals; Biogenic Monoamines; Body Temperature; Brain Chemistry; Diuretics; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Synaptosomes | 2001 |
Gender-dependent enhanced adult neurotoxic response to methamphetamine following fetal exposure to the drug.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Fever; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Neurotoxicity Syndromes; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Sex Characteristics | 2001 |
Tolerance to the neurotoxic effects of methamphetamine in young rats.
Topics: Age Factors; Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Drug Tolerance; Hyperthermia, Induced; Male; Methamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley | 2002 |