methamphetamine has been researched along with Aging in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.13) | 18.7374 |
| 1990's | 17 (21.52) | 18.2507 |
| 2000's | 23 (29.11) | 29.6817 |
| 2010's | 21 (26.58) | 24.3611 |
| 2020's | 10 (12.66) | 2.80 |
| Authors | Studies |
|---|---|
| Benya-Aphikul, H; Chetprayoon, P; Pongrakhananon, V; Rodsiri, R; Sooksawate, T | 1 |
| Chen, PY; Chen, YL; Chou, WH; Huang, MC; Lin, YF; Liu, HC | 1 |
| Bruneau, J; Høj, SB; Larney, S; Makarenko, I; Minoyan, N; Zolopa, C | 1 |
| Ellis, JD; Huhn, AS | 1 |
| Jordan Walter, T; Minassian, A; Perry, W; Young, JW | 1 |
| Chebolu, S; Darmani, NA; Kamali, S; Skegrud, S; Sun, Y | 1 |
| Benterkia, A; Harastani, M; Nait-Ali, A; Zadeh, FM | 1 |
| Shukla, M; Vincent, B | 1 |
| Cookson, D; Ellis, RJ; Grant, I; Heaton, R; Iudicello, JE; Karris, M; Letendre, S; Lin, J; Mehta, SR; Morgan, E; Okwuegbuna, O; Saloner, R | 1 |
| Fu, L; Li, SQ; Pei, W; Yu, Y | 1 |
| Apostolopoulos, V; Fraser, S; Nurgali, K; Papageorgiou, M; Raza, A | 1 |
| Izquierdo, A; Phillips, TJ; Pozos, H; Ye, T | 1 |
| Gonzalez, AE; McDougall, SA; Mohd-Yusof, A; Veliz, A | 1 |
| Klaschka, J; Rípová, D; Schutová, B; Šlamberová, R; Stěpánková, H; Vrajová, M | 1 |
| Bryant, S; Dawson, BL; Doyle, HH; Helton, AK; Lloyd, SA; Picou, BN; Ross, JM; Schulz, J; Shanks, RA; Tavares, C | 1 |
| Berry, MJ; Chang, L; Munsaka, S; Panee, J; Pang, X | 1 |
| Fleckenstein, AE; Hanson, GR; McFadden, LM; Nielsen, SM; Smith, MD; Vieira-Brock, PL | 1 |
| Ellis, JD; Fleckenstein, AE; Hanson, GR; McFadden, LM; McIntosh, JM; Nielsen, SM; Stout, KA; Vieira-Brock, PL; Walters, ET; Wilkins, DG | 1 |
| Furuie, H; Ichitani, Y; Yamada, K | 1 |
| Atkinson, JH; Cattie, J; Cherner, M; Grant, I; Montoya, JL; Moore, DJ; Morgan, E; Woods, SP | 1 |
| Engleman, EA; Katner, SN; Neal-Beliveau, BS | 1 |
| Brown, RW; Harrod, SB; Lacy, RT; Mactutus, CF; Morgan, AJ | 1 |
| Iwata, K; Iwata, Y; Matsuzaki, H; Mori, N; Nakahara, D; Nakamura, K; Shinmura, C; Suda, S; Sugihara, G; Suzuki, K; Takei, N; Tsuchiya, KJ; Ueki, T; Wakuda, T; Yamamoto, S | 1 |
| Aston, J; Banerjee, PS; Khundakar, AA; Zetterström, TS | 1 |
| Mayhorn, J; Minamoto, T; Odell, JR; White, IM; White, W | 1 |
| Bagorda, F; Brummelte, S; Schaefers, AT; Teuchert-Noodt, G | 1 |
| Cadet, JL; Cesena, A; Hodges, AB; Hohmann, CF; Ivanova, E; Krasnova, IN; Ladenheim, B; Phillip, CG; Rhoades, R | 1 |
| Gupta, T; Lewicki, AD; Patel, K; Rhodes, JS; Zombeck, JA | 1 |
| Itoh, H; Kurachi, M; Matsuoka, T; Seo, T; Sumiyoshi, T; Suzuki, M; Uehara, T | 1 |
| Good, RL; Radcliffe, RA | 1 |
| Chang, L; Ernst, T; Fein, G; Jiang, CS; Nakama, H; Shimotsu, R | 1 |
| Castellanos, KA; Greenfield, VY; Gutierrez, A; Horn, LR; Kozanian, OO; McDougall, SA; Mohd-Yusof, A | 1 |
| Elsworth, JD; Morrow, BA; Redmond, DE; Roth, RH | 1 |
| Matuszewich, L; Moenk, MD | 1 |
| Alves, CJ; de Sousa, L; Magalhães, A; Melo, P; Moradas-Ferreira, P; Summavielle, T; Tavares, MA | 1 |
| Buell, M; Geyer, MA; Henry, BL; Minassian, A; Perry, W; Young, JW | 1 |
| Fujiyama, K; Hiraoka, S; Kajii, Y; Muraoka, S; Nishikawa, T; Umino, A | 1 |
| Bagorda, F; Busche, A; Dawirs, RR; Horstmann, S; Moll, GH; Neddens, J; Teuchert-Noodt, G | 1 |
| Fukui, R; Greengard, P; Higashi, H; Matsuishi, T; Nairn, AC; Nishi, A; Svenningsson, P | 1 |
| Ballard, ME; Bennani, YL; Bitner, RS; Browman, KE; Buckley, MJ; Cowart, MD; Decker, MW; Drescher, KU; Esbenshade, TA; Faghih, R; Fox, GB; Hancock, AA; Komater, VA; Krueger, KM; Lemaire, M; Marsh, K; Miner, H; Pan, JB; Porsolt, RD; Radek, RJ; Rueter, LE; Sullivan, JP; Wetter, J; Yao, BB; Zhang, M | 1 |
| Anderson, LI; Dluzen, DE; Leipheimer, RE | 1 |
| Curtis, WR; Palmiter, RD; Perez, FA | 1 |
| Brown, JM; Cox, BM; Gouty, S; Iyer, V; Rosenberger, J | 1 |
| Fleckenstein, AE; Hanson, GR; Volz, TJ | 1 |
| Brummelte, S; Neddens, J; Teuchert-Noodt, G | 1 |
| Raber, J | 1 |
| Harvey, DC; Laćan, G; Melega, WP; Way, BM | 1 |
| Day-Pfeiffer, H; Martin, DC; Martin, JC; Sigman, G | 1 |
| Martin, DC; Martin, JC | 1 |
| Bowyer, JF | 1 |
| Ali, SF; Bowyer, JF; Holson, RR; Newport, GD; Slikker, W | 1 |
| Acuff-Smith, KD; Ahrens, KG; Fisher, JE; Schilling, MA; Vorhees, CV | 2 |
| Minamoto, Y; Ono, M; Shibata, S; Watanabe, S | 1 |
| Bowyer, JF; Gough, B; Holson, RR; Lipe, GW; Newport, GD; Slikker, W | 1 |
| Akiyama, K; Fujiwara, Y; Kanzaki, A; Tsuchida, K; Ujike, H | 1 |
| Azzalis, LA; Camarini, R; Carlini, EA; D'Almeida, V; Junqueira, VB; Mattei, R | 1 |
| Camp, R; Carroll, M; Pecha, BS; Pecha, RE; Prindiville, T; Trudeau, W | 1 |
| Cappon, GD; Morford, LL; Vorhees, CV | 1 |
| Ali, SF; Laws, SC; Miller, DB; O'Callaghan, JP | 1 |
| Gomes-Da-Silva, J; Silva, MC; Tavares, MA | 1 |
| Dawirs, RR; Hildebrandt, K; Teuchert-Noodt, G | 1 |
| Broening, HW; Fukumura, M; Inman-Wood, SL; Moran, MS; Morford, LL; Vorhees, CV | 1 |
| Richards, JB; Sabol, KE; Yung, K | 1 |
| Fleckenstein, AE; Hanson, GR; Kokoshka, JM; Wilkins, DG | 1 |
| Ali, SF; Miller, DB; O'Callaghan, JP | 1 |
| Ali, SF; Imam, SZ | 1 |
| Chen, HH; Cherng, CG; Hsu, CH; Kuo, Y; Yu, L | 1 |
| Hickey, MA; Morton, AJ; Reynolds, GP | 1 |
| Heim, F | 1 |
| Day, HE; Martin, DD; Martin, JC; Radow, B | 1 |
| Martin, DC; Martin, JC; Radow, B; Sigman, G | 1 |
| Maeda, N; Matsuoka, N; Ohkubo, Y; Yamaguchi, I; Yamazaki, M | 1 |
| Selden, LS | 1 |
| Wagner, GC; Walsh, SL | 1 |
| Dawirs, RR; Teuchert-Noodt, G | 1 |
| Fujiwara, Y; Kazahaya, Y; Nakashima, M; Otsuki, S; Sato, M | 1 |
| DeLanney, LE; Forno, LS; Irwin, I; Langston, E; Langston, JW; Ricaurte, GA | 1 |
| Bercu, G; Untea, G | 1 |
5 review(s) available for methamphetamine and Aging
| Article | Year |
|---|---|
Ageing and older people who use illicit opioids, cocaine or methamphetamine: a scoping review and literature map.
Topics: Aged; Aging; Analgesics, Opioid; Central Nervous System Stimulants; Cocaine; Humans; Methamphetamine; Quality of Life | 2022 |
The multi-faceted impact of methamphetamine on Alzheimer's disease: From a triggering role to a possible therapeutic use.
Topics: Aging; Alzheimer Disease; Brain; Central Nervous System Stimulants; Humans; Methamphetamine | 2020 |
Methamphetamine and its immune-modulating effects.
Topics: Aging; Animals; Central Nervous System Stimulants; Humans; Immune System; Immunologic Factors; Inflammation; Methamphetamine | 2019 |
Histamine receptor-mediated signaling during development and brain function in adulthood.
Topics: Aging; Animals; Brain; Histamine; Humans; Methamphetamine; Receptors, Histamine; Signal Transduction | 2007 |
Neurotoxicity of methamphetamine: mechanisms of action and issues related to aging.
Topics: Aging; Brain; Dopamine; Humans; Methamphetamine; Neurons; Oxidation-Reduction; Serotonin | 1991 |
74 other study(ies) available for methamphetamine and Aging
| Article | Year |
|---|---|
Neuronal growth and synaptogenesis are inhibited by prenatal methamphetamine exposure leading to memory impairment in adolescent and adult mice.
Topics: Aging; Animals; Female; Memory Disorders; Methamphetamine; Mice; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Synapses | 2021 |
Shortened leukocyte telomere length in young adults who use methamphetamine.
Topics: Adult; Aging; Humans; Leukocytes; Methamphetamine; Telomere; Telomere Shortening; Young Adult | 2021 |
Commentary on Zolopa et al.: Trauma as an impediment to successful aging and a precipitant of opioid and stimulant use among older adults.
Topics: Aged; Aging; Analgesics, Opioid; Central Nervous System Stimulants; Humans; Methamphetamine | 2022 |
Combined prior chronic methamphetamine treatment and gp120 expression reduce PPI in aged male but not female mice.
Topics: Aged; Aging; Animals; Female; HIV Infections; Humans; Male; Methamphetamine; Mice; Prepulse Inhibition; Sensory Gating | 2022 |
Effects of low-doses of methamphetamine on d-fenfluramine-induced head-twitch response (HTR) in mice during ageing and c-fos expression in the prefrontal cortex.
Topics: Adrenergic Agents; Aging; Animals; Fenfluramine; Humans; Methamphetamine; Mice; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Receptor, Serotonin, 5-HT2A; Serotonin | 2023 |
Methamphetamine drug abuse and addiction: Effects on face asymmetry.
Topics: Adolescent; Adult; Aged; Aging; Amphetamine-Related Disorders; Biometry; Child; Databases, Factual; Face; Facial Asymmetry; Humans; Methamphetamine; Middle Aged; Young Adult | 2020 |
Telomere length is associated with HIV infection, methamphetamine use, inflammation, and comorbid disease risk.
Topics: Adult; Aging; Amphetamine-Related Disorders; Biomarkers; Cohort Studies; Comorbidity; Cross-Sectional Studies; Female; HIV Infections; Humans; Inflammation Mediators; Male; Methamphetamine; Middle Aged; Risk Factors; Telomere | 2021 |
Brain transcriptomics of nonhuman primates: A review.
Topics: Aging; Animals; Brain; Brain Diseases; Disease Models, Animal; Ethanol; Humans; Methamphetamine; Neurosciences; Primates; RNA-Seq; Sevoflurane; Transcriptome; Valproic Acid | 2021 |
Long-term effects of exposure to methamphetamine in adolescent rats.
Topics: Aging; Animals; Choice Behavior; Discrimination Learning; Learning Disabilities; Male; Methamphetamine; Rats; Reversal Learning; Self Administration | 2014 |
Role of the D1 receptor for the dopamine agonist-induced one-trial behavioral sensitization of preweanling rats.
Topics: Aging; Animals; Apomorphine; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Cocaine; Dopamine Agonists; Female; Learning; Male; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2014 |
Age-related differences in NMDA receptor subunits of prenatally methamphetamine-exposed male rats.
Topics: Aging; Animals; Animals, Newborn; Female; Hippocampus; Male; Methamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Protein Subunits; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2014 |
Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Locomotion; Male; Methamphetamine; Methylphenidate; Mice; Mice, Inbred C57BL; Motor Activity; Sex Factors; Time Factors | 2015 |
Independent and co-morbid HIV infection and Meth use disorders on oxidative stress markers in the cerebrospinal fluid and depressive symptoms.
Topics: Aging; Amphetamine-Related Disorders; Biomarkers; Dementia; Depression; Female; HIV Infections; Humans; Male; Methamphetamine; Middle Aged; Oxidative Stress; Psychiatric Status Rating Scales | 2015 |
Nicotine Administration Attenuates Methamphetamine-Induced Novel Object Recognition Deficits.
Topics: Administration, Oral; Aging; Animals; CA1 Region, Hippocampal; Dentate Gyrus; Drinking Water; Exploratory Behavior; Male; Memory Disorders; Methamphetamine; Nicotine; Nicotinic Agonists; Nootropic Agents; Rats, Sprague-Dawley; Receptors, Nicotinic; Recognition, Psychology; Serotonin Plasma Membrane Transport Proteins; Temporal Lobe | 2015 |
Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits.
Topics: Age of Onset; Aging; Animals; Autoradiography; Bridged Bicyclo Compounds, Heterocyclic; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Male; Methamphetamine; Nicotine; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2015 |
Chronic NMDA receptor blockade in early postnatal period, but not in adulthood, impairs methamphetamine-induced conditioned place preference in rats.
Topics: Aging; Animals; Animals, Newborn; Central Nervous System Stimulants; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Methamphetamine; Motor Activity; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Space Perception; Spatial Behavior | 2016 |
The impact of age, HIV serostatus and seroconversion on methamphetamine use.
Topics: Adult; Aging; AIDS Serodiagnosis; Amphetamine-Related Disorders; Female; HIV Infections; Humans; Male; Methamphetamine; Middle Aged; Risk-Taking; Seroconversion; Young Adult | 2016 |
Embryonic Methamphetamine Exposure Inhibits Methamphetamine Cue Conditioning and Reduces Dopamine Concentrations in Adult N2 Caenorhabditis elegans.
Topics: Aging; Animals; Behavior, Addictive; Caenorhabditis elegans; Conditioning, Psychological; Dopamine; Male; Methamphetamine | 2016 |
Intravenous Prenatal Nicotine Exposure Alters METH-Induced Hyperactivity, Conditioned Hyperactivity, and BDNF in Adult Rat Offspring.
Topics: Aging; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dopamine; Female; Hyperkinesis; Male; Methamphetamine; Motor Activity; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects | 2016 |
Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Asphyxia; Behavior, Animal; Cell Count; Central Nervous System Stimulants; Cerebellar Nuclei; Cesarean Section; Female; Hyperkinesis; Methamphetamine; Models, Biological; Motor Activity; Obstetric Labor Complications; Pregnancy; Rats; Rats, Sprague-Dawley | 2008 |
Differential regulation of psychostimulant-induced gene expression of brain derived neurotrophic factor and the immediate-early gene Arc in the juvenile and adult brain.
Topics: Aging; Amphetamine; Animals; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Cytoskeletal Proteins; Down-Regulation; Gene Expression Regulation; Genes, Immediate-Early; Male; Methamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley | 2009 |
Brief exposure to methamphetamine (METH) and phencyclidine (PCP) during late development leads to long-term learning deficits in rats.
Topics: Aging; Analysis of Variance; Animals; Conditioning, Operant; Learning; Learning Disabilities; Male; Methamphetamine; Motor Activity; Phencyclidine; Rats; Rats, Wistar; Social Behavior; Spatial Behavior | 2009 |
Effect of postnatal methamphetamine trauma and adolescent methylphenidate treatment on adult hippocampal neurogenesis in gerbils.
Topics: Administration, Oral; Aging; Animals; Bromodeoxyuridine; Dentate Gyrus; Gerbillinae; Hippocampus; Injections; Methamphetamine; Methylphenidate; Neurogenesis; Sodium Chloride; Time Factors | 2009 |
Methamphetamine treatment causes delayed decrease in novelty-induced locomotor activity in mice.
Topics: Age Factors; Aging; Amphetamine-Related Disorders; Animals; Brain; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Exploratory Behavior; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Motor Activity; Nerve Degeneration; Presynaptic Terminals | 2009 |
Patterns of neural activity associated with differential acute locomotor stimulation to cocaine and methamphetamine in adolescent versus adult male C57BL/6J mice.
Topics: Aging; Animals; Brain; Caudate Nucleus; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurons; Proto-Oncogene Proteins c-fos | 2010 |
Neonatal exposure to MK-801, an N-methyl-D-aspartate receptor antagonist, enhances methamphetamine-induced locomotion and disrupts sensorimotor gating in pre- and postpubertal rats.
Topics: Aging; Animals; Animals, Newborn; Antipsychotic Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; Locomotion; Methamphetamine; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia | 2010 |
Methamphetamine-induced locomotor changes are dependent on age, dose and genotype.
Topics: Adolescent; Aging; Animals; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Genotype; Humans; Illicit Drugs; Male; Methamphetamine; Mice; Mice, 129 Strain; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Models, Animal; Motor Activity; Species Specificity | 2011 |
Methamphetamine users show greater than normal age-related cortical gray matter loss.
Topics: Adolescent; Adult; Age Factors; Aging; Amphetamine-Related Disorders; Blood Pressure; Central Nervous System Stimulants; Cerebral Cortex; Cross-Sectional Studies; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Illicit Drugs; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methamphetamine; Middle Aged; Neuroimaging; Young Adult | 2011 |
One-trial behavioral sensitization in preweanling rats: differential effects of cocaine, methamphetamine, methylphenidate, and D-amphetamine.
Topics: Aging; Animals; Animals, Suckling; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Male; Methamphetamine; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Weaning | 2011 |
Impact of methamphetamine on dopamine neurons in primates is dependent on age: implications for development of Parkinson's disease.
Topics: Aging; Animals; Brain; Central Nervous System Stimulants; Chlorocebus aethiops; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Methamphetamine; Neurons; Parkinson Disease; Tissue Distribution; Tyrosine 3-Monooxygenase | 2011 |
Juvenile but not adult methamphetamine exposure improves performance in the Morris Water Maze in male rats.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Central Nervous System Stimulants; Locomotion; Male; Maze Learning; Methamphetamine; Rats; Rats, Sprague-Dawley; Reaction Time; Swimming; Time Factors | 2012 |
Methamphetamine mimics the neurochemical profile of aging in rats and impairs recognition memory.
Topics: Age Factors; Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Memory Disorders; Methamphetamine; Rats; Rats, Wistar; Recognition, Psychology; Serotonin; Time Factors | 2012 |
Behavioral effects of chronic methamphetamine treatment in HIV-1 gp120 transgenic mice.
Topics: Aging; Amphetamine-Related Disorders; Animals; Behavior, Animal; Body Temperature; Body Weight; Central Nervous System Stimulants; Darkness; Dose-Response Relationship, Drug; Exploratory Behavior; Female; HIV Envelope Protein gp120; HIV Infections; Light; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Sex Characteristics | 2013 |
A developmentally regulated and psychostimulant-inducible novel rat gene mrt1 encoding PDZ-PX proteins isolated in the neocortex.
Topics: Aging; Amino Acid Sequence; Animals; Antibodies; Base Sequence; DNA Primers; DNA, Complementary; Gene Expression Regulation, Developmental; Methamphetamine; Molecular Sequence Data; Neocortex; Nerve Tissue Proteins; Peptide Fragments; Polymerase Chain Reaction; Rats | 2003 |
Epigenetic factors differentially influence postnatal maturation of serotonin (5-HT) innervation in cerebral cortex of gerbils: interaction of rearing conditions and early methamphetamine challenge.
Topics: Aging; Animals; Animals, Newborn; Cell Count; Central Nervous System Stimulants; Cerebral Cortex; Environment; Gerbillinae; Immunohistochemistry; Male; Methamphetamine; Nerve Fibers; Neurons; Serotonin | 2003 |
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Topics: Aging; Animals; Animals, Newborn; Benzazepines; Cocaine; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Immunoblotting; In Vitro Techniques; Male; Methamphetamine; Methylphenidate; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Signal Transduction; Threonine | 2003 |
Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 re
Topics: Aging; Animals; Avoidance Learning; Benzofurans; Central Nervous System Stimulants; Cognition Disorders; Dose-Response Relationship, Drug; Drinking; Electroencephalography; Histamine Antagonists; Hyperkinesis; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred DBA; Microdialysis; Neurons; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred SHR; Receptors, Histamine H3; Reflex, Startle; Schizophrenia; Social Behavior | 2005 |
Effects of neonatal and prepubertal hormonal manipulations upon estrogen neuroprotection of the nigrostriatal dopaminergic system within female and male mice.
Topics: Aging; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Estrogens; Female; Gonads; Male; Methamphetamine; Mice; Neostriatum; Neural Pathways; Neuroprotective Agents; Orchiectomy; Ovariectomy; Sex Characteristics; Sexual Maturation; Substantia Nigra; Testosterone | 2005 |
Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity.
Topics: Aging; Animals; Dopamine; Drug Resistance; Methamphetamine; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Oxidopamine; Ubiquitin; Ubiquitin-Protein Ligases | 2005 |
Differential protection against MPTP or methamphetamine toxicity in dopamine neurons by deletion of ppN/OFQ expression.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Female; Gene Deletion; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Knockout; Neurons; Protein Precursors; Receptors, Opioid; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics | 2006 |
Kinetic analysis of developmental changes in vesicular monoamine transporter-2 function.
Topics: Aging; Algorithms; Animals; Blotting, Western; Dopamine; Dopamine Uptake Inhibitors; Electrophysiology; Immunohistochemistry; In Vitro Techniques; Kinetics; Methamphetamine; Rats; Synaptosomes; Vesicular Monoamine Transport Proteins | 2006 |
Alteration in the GABAergic network of the prefrontal cortex in a potential animal model of psychosis.
Topics: Aging; Animals; Cell Differentiation; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment Design; gamma-Aminobutyric Acid; Gerbillinae; Interneurons; Male; Methamphetamine; Nerve Net; Prefrontal Cortex; Presynaptic Terminals; Psychotic Disorders; Pyramidal Cells; Sensory Deprivation; Synapses; Synaptic Transmission | 2007 |
Methamphetamine increases basal ganglia iron to levels observed in aging.
Topics: Aging; Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System Stimulants; Chlorocebus aethiops; Disease Models, Animal; Dopamine; Ferritins; Globus Pallidus; Iron; Iron Metabolism Disorders; Male; Methamphetamine; Oxidative Stress; Species Specificity; Substantia Nigra; Tyrosine 3-Monooxygenase | 2007 |
Saccharin preferences in food deprived aging rats are altered as a function of perinatal drug exposure.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Drinking; Female; Fetus; Food Deprivation; Food Preferences; Methamphetamine; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Saccharin | 1983 |
Voluntary activity in the aging rat as a function of maternal drug exposure.
Topics: Aging; Animals; Female; Life Expectancy; Methamphetamine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1981 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; Frontal Lobe; Glutamates; Glutamic Acid; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methylaspartate; Phencyclidine; Pipecolic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1993 |
Methamphetamine exposure during early postnatal development in rats: I. Acoustic startle augmentation and spatial learning deficits.
Topics: Acoustic Stimulation; Aging; Animals; Animals, Newborn; Body Weight; Female; Habituation, Psychophysiologic; Male; Maze Learning; Memory; Methamphetamine; Motor Activity; Rats; Rats, Inbred Strains; Reflex, Startle; Space Perception | 1994 |
Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge.
Topics: Aging; Animals; Animals, Newborn; Arousal; Cognition; Female; Male; Methamphetamine; Motor Activity; Movement; Rats; Videotape Recording | 1994 |
Aging impairs methamphetamine-induced free-running and anticipatory locomotor activity rhythms in rats.
Topics: Aging; Animals; Circadian Rhythm; Drinking; Male; Methamphetamine; Motor Activity; Rats; Rats, Wistar | 1994 |
Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Cold Temperature; Dialysis; Dopamine; Female; Glutamates; Glutamic Acid; Hippocampus; Methamphetamine; Putamen; Rats; Rats, Sprague-Dawley; Serotonin; Taurine | 1993 |
Ontogeny of enhanced striatal dopamine release in rats with methamphetamine-induced behavioral sensitization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Male; Methamphetamine; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley | 1994 |
Antioxidant defense in rat brain after chronic treatment with anorectic drugs.
Topics: Aging; Animals; Antioxidants; Appetite Depressants; Brain; Catalase; Dopamine Uptake Inhibitors; Glutathione; Glutathione Peroxidase; Male; Mazindol; Methamphetamine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 1995 |
Association of cocaine and methamphetamine use with giant gastroduodenal ulcers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Child; Cocaine; Endoscopy; Female; Humans; Male; Methamphetamine; Middle Aged; Peptic Ulcer; Prognosis | 1996 |
Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response.
Topics: Aging; Analysis of Variance; Animals; Body Temperature Regulation; Caudate Nucleus; Dopamine; Fever; Glial Fibrillary Acidic Protein; Methamphetamine; Neurotoxins; Putamen; Rats; Rats, Sprague-Dawley; Serotonin; Temperature | 1997 |
The impact of gender and estrogen on striatal dopaminergic neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Corpus Striatum; Dopamine; Estradiol; Female; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxins; Organ Size; Ovariectomy; Sex Characteristics; Uterus | 1998 |
Developmental exposure to methamphetamine: a neonatal model in the rat.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Female; Male; Methamphetamine; Rats; Rats, Wistar; Reference Values; Time Factors; Weight Gain | 1998 |
A single neonatal dose of methamphetamine suppresses dentate granule cell proliferation in adult gerbils which is restored to control values by acute doses of haloperidol.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Division; Dentate Gyrus; Gerbillinae; Haloperidol; Male; Methamphetamine; Reference Values | 1999 |
Adult learning deficits after neonatal exposure to D-methamphetamine: selective effects on spatial navigation and memory.
Topics: Aging; Animals; Animals, Newborn; Cues; Dose-Response Relationship, Drug; Learning Disabilities; Maze Learning; Memory; Memory Disorders; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Space Perception | 2000 |
The effects of high-dose methamphetamine in the aging rat: differential reinforcement of low-rate 72-s schedule behavior and neurochemistry.
Topics: Aging; Animals; Behavior, Animal; Brain; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Male; Methamphetamine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Serotonin; Temperature | 2000 |
Age-dependent differential responses of monoaminergic systems to high doses of methamphetamine.
Topics: Age Factors; Aging; Amphetamine-Related Disorders; Animals; Biogenic Monoamines; Brain; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Fever; Frontal Lobe; Hippocampus; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Synaptosomes; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2000 |
Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Area Under Curve; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Models, Biological; Neurotoxicity Syndromes; Sex Factors; Time Factors | 2000 |
Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Fever; Homovanillic Acid; Male; Methamphetamine; Nitrates; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Ovarian hormones do not attenuate methamphetamine-induced dopaminergic neurotoxicity in mice gonadectomized at 4 weeks postpartum.
Topics: Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Male; Methamphetamine; Mice; Neurotoxins; Ovariectomy; Progesterone; Tamoxifen | 2002 |
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate | 2002 |
[The correlations between aging and drug effects (author's transl)].
Topics: Age Factors; Aging; Animals; Caffeine; Cysteamine; Energy Metabolism; Glycolysis; Hepatectomy; Humans; Inactivation, Metabolic; Liver; Methamphetamine; Oxygen Consumption; Pharmacology; Testosterone | 1976 |
Life span and pathology in offspring following nicotine and methamphetamine exposure.
Topics: Age Factors; Aging; Animals; Behavior, Animal; Body Weight; Female; Fetus; Life Expectancy; Male; Methamphetamine; Neoplasms, Experimental; Nicotine; Pregnancy; Rats; Sodium Chloride | 1979 |
Growth, development and activity in rat offspring following maternal drug exposure.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Birth Weight; Body Weight; Female; Gestational Age; Growth Disorders; Male; Maternal-Fetal Exchange; Methamphetamine; Motor Activity; Nicotine; Pregnancy; Rats | 1976 |
Effect of FR121196, a novel cognitive enhancer, on the memory impairment of rats in passive avoidance and radial arm maze tasks.
Topics: Aging; Animals; Avoidance Learning; Brain; Choline O-Acetyltransferase; Cognition Disorders; Dementia; Discrimination Learning; Disease Models, Animal; Male; Memory Disorders; Methamphetamine; Motor Activity; Physostigmine; Piperazines; Rats; Rats, Inbred F344; Rats, Wistar; Scopolamine; Sulfonamides | 1992 |
Evaluation of the effects of inhibition of monoamine oxidase and senescence on methamphetamine-induced neuronal damage.
Topics: Aging; Animals; Clorgyline; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nervous System Diseases; Neurons; Selegiline | 1991 |
Age-related toxicity in prefrontal cortex and caudate-putamen complex of gerbils (Meriones unguiculatus) after a single dose of methamphetamine.
Topics: Aging; Animals; Brain; Gerbillinae; Injections, Intraperitoneal; Lysosomes; Male; Methamphetamine; Neurons | 1991 |
Behavioral sensitization to methamphetamine in the rat: an ontogenic study.
Topics: Aging; Animals; Behavior, Animal; Female; Methamphetamine; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1987 |
Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Degeneration; Pyridines; Substantia Nigra | 1987 |
[Considerations on the influence of treatment with Gerovital H3 (lozenges) on working capacity of active persons over 45 years of age].
Topics: Aging; Fatigue; Female; Humans; Male; Methamphetamine; Middle Aged; Muscles; Nervous System; Work | 1969 |