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methadyl acetate and Chemical Dependence

methadyl acetate has been researched along with Chemical Dependence in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (72.55)	18.7374
1990's	6 (11.76)	18.2507
2000's	8 (15.69)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brady, J; Brooner, R; Butler, C; Kuo, I; Schwartz, R; Strathdee, SA; Vlahov, D	1
Colker, AC	1
Horst, DA; Humphreys, K; Minkel, JD; Oliva, EM; Trafton, JA	1
Cunningham-Rathner, J; Ling, W; Rawson, R	1
Acri, J; Elkashef, A; Vocci, FJ	1
Humphreys, K; McKellar, JD; Trafton, JA; Villafranca, SW	1
France, CP; Galici, R; Gerak, LR	1
Dewey, WL	1
Braude, M; Brockman, H; Brusick, D; Hung, C; Jagannath, D; Matheson, D	1
Benowitz, N; Hargreaves, WA; Sorensen, JL; Tyler, J; Weinberg, JA	1
Lichtblau, L; Mercurio, SD; Sparber, SB	1
Fraser, HF; Gorodetzky, CW; Kay, DC; Yeh, SY	1
Burklund, KE; Lichtblau, L; Sparber, SB	1
Khazan, N; Steinfels, GF; Wolf, DL; Young, GA	1
Khazan, N; Steinfels, GF; Young, GA	3
Wodak, A	1
Miguel, N; Patricio, LD	1
Bigelow, GE; Brooner, RK; Eissenberg, T; Johnson, RE; Stitzer, ML; Strain, EC; Walsh, SL	1
Gygi, SP; Nagasawa, PR; Rollins, DE; Valdez, AS; Wilkins, DG	1
Brandt, MR; France, CP	1
Allen, JP; Litten, RZ	1
Huang, W; Moody, DE; Nelson, AC	1
Fraser, HF; Isbell, H; Nash, TL; Vanhorn, GD	1
Serban, G	1
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M	1
Greenstein, R; O'Brien, CP; Woody, GE	1
Khazan, N; Meltzer, LT; Moreton, JE; Young, GA	1
Inturrisi, CE; Kaiko, RF	1
Jasinski, DR	1
Dogoloff, LI	1
Chiba, S; Khazan, N; Moreton, JE; Young, GA	1
Chiba, S; Khazan, N; Moreton, EJ	1
Goldstein, A; Judson, B	1
Blachly, P; Carter, CC; Irwin, S; Marks, J	1
Jaffe, JH; Senay, EC	1
Archer, S	1
Swanson, DA	1
Blachly, PH	1
Blachly, PH; David, NA; Irwin, S	1
Fraser, HF; Isbell, H	1
Goldstein, A	2
Henderson, GL	1
Inturrisi, C; Kaiki, RF	1
Chen, RC; Ho, AK	1
Kauders, F; Schecter, A	1
Schuster, CR; Snyder, M	1
Dorozynsky, L; McGahan, P; McLellan, AT; Zangwell, BC	1

Reviews

6 review(s) available for methadyl acetate and Chemical Dependence

Article	Year
Behavioral health issue brief: pharmacotherapy treatment of alcoholism and drug addiction: overview and bibliography: year end report-2002. Issue brief (Health Policy Tracking Service), 2002, Dec-31 Topics: Alcohol Deterrents; Alcoholism; Analgesics, Opioid; Buprenorphine; Drug Therapy; Humans; Methadone; Methadyl Acetate; Naltrexone; Narcotic Antagonists; Substance-Related Disorders; United States	2002
Medication development for addictive disorders: the state of the science. The American journal of psychiatry, 2005, Volume: 162, Issue:8 Topics: Animals; Buprenorphine; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cocaine-Related Disorders; Dopamine; Drug Design; Drug Industry; Drug Therapy, Combination; Humans; Methadyl Acetate; Naloxone; National Institutes of Health (U.S.); Opioid-Related Disorders; Program Development; Secondary Prevention; Substance-Related Disorders; United States	2005
Possible influence of opioid normetabolites on the onset, magnitude and quality of the opioid abstinence syndrome. Drug and alcohol dependence, 1980, Volume: 5, Issue:4 Topics: Administration, Oral; Animals; Biotransformation; Body Weight; Codeine; Dealkylation; Dextropropoxyphene; Dogs; Guinea Pigs; Humans; Injections, Subcutaneous; Levorphanol; Meperidine; Methadyl Acetate; Morphine; Narcotics; Rabbits; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1980
Managing illicit drug use. A practical guide. Drugs, 1994, Volume: 47, Issue:3 Topics: Buprenorphine; Counseling; Disulfiram; Humans; Methadone; Methadyl Acetate; Naltrexone; Psychotherapy; Self-Help Groups; Substance Abuse Treatment Centers; Substance-Related Disorders	1994
Medications for alcohol, illicit drug, and tobacco dependence. An update of research findings. Journal of substance abuse treatment, 1999, Volume: 16, Issue:2 Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Buprenorphine; Bupropion; Forecasting; Humans; Methadyl Acetate; Naltrexone; Substance-Related Disorders; Taurine; Tobacco Use Disorder	1999
Pharmacology of LAAM. NIDA research monograph, 1976, Issue:8 Topics: Analgesics; Animals; Behavior, Animal; Dogs; Drug Evaluation, Preclinical; Female; Haplorhini; Humans; Kinetics; Male; Methadone; Methadyl Acetate; Mice; Morphine; Nalorphine; Rabbits; Rats; Stereoisomerism; Substance-Related Disorders; Time Factors	1976

Trials

7 trial(s) available for methadyl acetate and Chemical Dependence

Article	Year
Dose-related efficacy of levomethadyl acetate for treatment of opioid dependence. A randomized clinical trial. JAMA, 1997, Jun-25, Volume: 277, Issue:24 Topics: Adult; Analysis of Variance; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heroin; Heroin Dependence; Humans; Male; Methadyl Acetate; Middle Aged; Narcotics; Substance-Related Disorders; Treatment Outcome	1997
Use of miotic effect in evaluating analgesic drugs in man. 1954 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Analgesics, Opioid; Clinical Trials as Topic; Euphoria; Humans; Methadyl Acetate; Miotics; Substance Withdrawal Syndrome; Substance-Related Disorders	1976
Multimodality treatment of narcotic addiction: an overview. NIDA research monograph, 1978, Issue:19 Topics: Ambulatory Care; Behavior Therapy; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Humans; Methadone; Methadyl Acetate; Narcotic Antagonists; Narcotics; Psychoses, Substance-Induced; Psychotherapy; Substance-Related Disorders; Therapeutic Community	1978
Can the community be protected against the hazards of take-home methadone? 1974 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Administration, Oral; Clinical Trials as Topic; Humans; Male; Methadone; Methadyl Acetate; Social Problems; Substance-Related Disorders	1976
Preliminary observations with acute and chronic methadone and 1-alpha-acetylmethadol administration in humans. NIDA research monograph, 1976, Issue:8 Topics: Clinical Trials as Topic; Drug Administration Schedule; Drug Tolerance; Female; Humans; Male; Methadone; Methadyl Acetate; Morphine; Substance-Related Disorders; Time Factors	1976
Methadone and 1-methadyl acetate: use in management of narcotic addicts. 1971 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Clinical Trials as Topic; Drug Evaluation; Humans; Male; Methadone; Methadyl Acetate; Narcotics; Substance-Related Disorders	1976
How effective is LAAM treatment? Clinical comparison with methadone. NIDA research monograph, 1986, Volume: 67 Topics: Alcohol Drinking; Alcoholic Intoxication; Clinical Trials as Topic; Follow-Up Studies; Humans; Male; Methadone; Methadyl Acetate; Substance-Related Disorders	1986

Other Studies

38 other study(ies) available for methadyl acetate and Chemical Dependence

Article	Year
Feasibility of referring drug users from a needle exchange program into an addiction treatment program: experience with a mobile treatment van and LAAM maintenance. Journal of substance abuse treatment, 2003, Volume: 24, Issue:1 Topics: Adult; Baltimore; Cocaine-Related Disorders; Feasibility Studies; Female; Heroin Dependence; Humans; Male; Methadyl Acetate; Mobile Health Units; Narcotics; Needle-Exchange Programs; Referral and Consultation; Severity of Illness Index; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors; Treatment Outcome	2003
Treatment needs associated with pain in substance use disorder patients: implications for concurrent treatment. Drug and alcohol dependence, 2004, Jan-07, Volume: 73, Issue:1 Topics: Adult; Analgesics, Opioid; Analysis of Variance; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Health Services; Health Services Needs and Demand; Humans; Hypnotics and Sedatives; Illicit Drugs; Male; Methadone; Methadyl Acetate; Middle Aged; Narcotics; Opioid-Related Disorders; Pain; Pain Measurement; Statistics as Topic; Substance-Related Disorders; United States; Utilization Review; Veterans	2004
Diffusion of substance abuse treatment: will buprenorphine be a success? Journal of psychoactive drugs, 2004, Volume: Suppl 2 Topics: Buprenorphine; Heroin Dependence; Humans; Methadone; Methadyl Acetate; Narcotic Antagonists; Narcotics; Substance-Related Disorders	2004
Predictors of retention in methadone programs: a signal detection analysis. Drug and alcohol dependence, 2006, Jul-27, Volume: 83, Issue:3 Topics: Adult; California; Combined Modality Therapy; Comorbidity; Counseling; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Health Services Research; Heroin Dependence; HIV Infections; Humans; Illicit Drugs; Male; Methadone; Methadyl Acetate; Middle Aged; Narcotics; Patient Dropouts; Patient Satisfaction; Risk-Taking; Socioeconomic Factors; Substance-Related Disorders; Veterans	2006
Self administration of cocaine in monkeys receiving LAAM acutely or chronically. Physiology & behavior, 2008, Jan-28, Volume: 93, Issue:1-2 Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Female; Macaca mulatta; Male; Methadyl Acetate; Narcotics; Reinforcement, Psychology; Self Administration; Substance-Related Disorders	2008
Various factors which affect the rate of development of tolerance and physical dependence to abused drugs. NIDA research monograph, 1984, Volume: 54 Topics: Animals; Body Weight; Drug Tolerance; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Reaction Time; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1984
Genetic screening of compounds used in drug abuse treatment. III. LAAM. Drug and chemical toxicology, 1981, Volume: 4, Issue:1 Topics: Animals; Bone Marrow Cells; DNA Repair; Drug Evaluation, Preclinical; Escherichia coli; Humans; In Vitro Techniques; Lymphoma; Methadone; Methadyl Acetate; Mice; Mutagens; Neoplasms, Experimental; Neurospora crassa; Salmonella typhimurium; Substance-Related Disorders	1981
(--)-alpha-Acetylmethadol effects on alcohol and diazepam use, sexual function and cardiac function. Drug and alcohol dependence, 1983, Volume: 12, Issue:4 Topics: Adult; Alcohol Drinking; Blood Pressure; Diazepam; Electrocardiography; Heart; Heart Rate; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Sexual Behavior; Substance-Related Disorders	1983
Separation of hepatic N-demethylase-inducing and opioid dependence-producing doses of levo-alpha-acetylmethadol in the pregnant rat. Life sciences, 1983, Sep-19, Volume: 33, Issue:12 Topics: Animals; Animals, Newborn; Body Weight; Dose-Response Relationship, Drug; Embryo Implantation; Ethylmorphine-N-Demethylase; Female; Fetal Resorption; Humans; Methadone; Methadyl Acetate; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Substance-Related Disorders	1983
A method for determining cumulative behavioral toxicity after chronic oral administration of l-alpha-acetylmethadol to female rats. Neurobehavioral toxicology, 1980,Spring, Volume: 2, Issue:1 Topics: Administration, Oral; Animals; Behavior, Animal; Drug Tolerance; Female; Fetus; Humans; Methadone; Methadyl Acetate; Morphine; Naloxone; Rats; Substance-Related Disorders	1980
Morphine challenges in levo-alpha-acetylmethadol (LAAM) post-addict rats. Life sciences, 1981, Mar-30, Volume: 28, Issue:13 Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine; Rats; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Wakefulness	1981
Relapse to morphine self-administration in morphine, methadone, and levo-alpha-acetylmethadol (LAAM) post-addict rats. Drug and alcohol dependence, 1981, Volume: 7, Issue:2 Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Rats; Self Administration; Sleep, REM; Substance-Related Disorders	1981
[Role of LAAM, methadone and naltrexone in the care of opiate dependence. Experience in Portugal]. Annales de medecine interne, 1994, Volume: 145 Suppl 3 Topics: Drug Administration Schedule; Female; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Naltrexone; Narcotics; Patient Compliance; Portugal; Substance-Related Disorders; Time Factors	1994
Incorporation of drugs for the treatment of substance abuse into pigmented and nonpigmented hair. Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:4 Topics: Animals; Area Under Curve; Buprenorphine; Chromatography, Liquid; Hair; Male; Mass Spectrometry; Methadone; Methadyl Acetate; Narcotics; Patient Compliance; Rats; Substance-Related Disorders	1998
Chronic l-alpha acetylmethadol in rhesus monkeys: discriminative stimulus and other behavioral measures of dependence and withdrawal. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3 Topics: Administration, Oral; Animals; Discrimination Learning; Injections, Intravenous; Macaca mulatta; Mental Disorders; Methadyl Acetate; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Substance-Related Disorders	1998
Variables in human liver microsome preparation: impact on the kinetics of l-alpha-acetylmethadol (LAAM) n-demethylation and dextromethorphan O-demethylation. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:3 Topics: Adolescent; Adult; Biomarkers; Cell Fractionation; Centrifugation; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Kinetics; Male; Methadyl Acetate; Methylation; Microsomes, Liver; Middle Aged; Smoking; Substance-Related Disorders; Sucrose	2001
New approach to the rehabilitation of the hard core drug addict (heroin methadone addicts) a pilot community study. The Journal of clinical psychiatry, 1978, Volume: 39, Issue:2 Topics: Anti-Anxiety Agents; Antidepressive Agents; Community Mental Health Services; Heroin Dependence; Humans; Methadone; Methadyl Acetate; Pilot Projects; Substance-Related Disorders	1978
Recent developments in chemotherapy of narcotic addiction, 3-4 November 1977, Washington, D.C.: proceedings. Annals of the New York Academy of Sciences, 1978, Volume: 311 Topics: Animals; Congresses as Topic; Endorphins; Humans; Methadone; Methadyl Acetate; Narcotic Antagonists; New York; Receptors, Opioid; Societies, Scientific; Substance-Related Disorders	1978
Dependence in rats after one injection of heroin-, LAAM- or hydromorphone-zinc tannate. Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3 Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Heroin; Heroin Dependence; Humans; Hydromorphone; Methadone; Methadyl Acetate; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders	1979
1-alpha-acetylmethadol (LAAM), methadone and morphine abstinence in dependent rats: EEG and behavioral correlates. Drug and alcohol dependence, 1977, Volume: 2, Issue:2 Topics: Animals; Behavior, Animal; Electroencephalography; Electromyography; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Rats; Sleep, REM; Substance Withdrawal Syndrome; Substance-Related Disorders	1977
Spontaneous vs. naloxone-induced abstinence in dependent rats self-administering L-alpha-acetylmethadol (LAAM) or morphine. Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4 Topics: Animals; Female; Humans; Methadone; Methadyl Acetate; Morphine Dependence; Naloxone; Rats; Self Administration; Sleep, REM; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1979
Pharmacodynamic profiles of 1-alpha-acetylmethadol (LAAM) and its N-demethylated metabolites, nor-LAAM and dinor-LAAM, during self-administration in the dependent rat. The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:3 Topics: Animals; Behavior, Animal; Conditioning, Operant; Dealkylation; Dose-Response Relationship, Drug; Electroencephalography; Humans; Methadone; Methadyl Acetate; Rats; Self Administration; Sleep, REM; Substance-Related Disorders; Time Factors	1979
Disposition of acetylmethadol in relation to pharmacologic action. Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:1 Topics: Adult; Biotransformation; Chromatography, Gas; Half-Life; Humans; Hydrogen-Ion Concentration; Kidney; Male; Methadone; Methadyl Acetate; Pupil; Substance-Related Disorders	1975
Recent developments in chemotherapy of narcotic addiction. Part VI. LAAM and narcotic antagonists: introductory remarks. Annals of the New York Academy of Sciences, 1978, Volume: 311 Topics: Humans; Methadyl Acetate; Narcotic Antagonists; Substance-Related Disorders	1978
Toward a coherent system of narcotic addiction treatment. Annals of the New York Academy of Sciences, 1978, Volume: 311 Topics: Crime; Government Agencies; Humans; International Cooperation; Methadyl Acetate; Public Policy; Substance-Related Disorders; United States	1978
Head-shake distributions during self-maintained dependence on morphine, methadone, and l-alpha-acetylmethadol (LAAM) in the rat. Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1 Topics: Animals; Behavior, Animal; Female; Humans; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Rats; Self Administration; Substance-Related Disorders	1977
Tolerance and cross tolerance to toxic effects of morphine, methadone and 1-alpha-acetylmethadol (LAAM) in naive and morphine dependent rats. Japanese journal of pharmacology, 1978, Volume: 28, Issue:3 Topics: Animals; Cross Reactions; Drug Tolerance; Female; Humans; Methadone; Methadyl Acetate; Morphine; Rats; Substance-Related Disorders	1978
Pharmacotherapy of opiate addiction. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, May-22, Volume: 50, Issue:22 Topics: Adolescent; Adult; Cyclazocine; Female; Heroin Dependence; Humans; Male; Methadone; Methadyl Acetate; Naltrexone; Opium; Substance-Related Disorders; United States	1976
1-Alpha-acetylmethoadol in the treatment of opiate addiction: progress report. 1971 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Drug Evaluation; Female; Humans; Male; Methadone; Methadyl Acetate; Patient Dropouts; Substance-Related Disorders	1976
1-Alpha-acetylmethadol (LAM): comparison of laboratory findings, electroencephalograms, and Cornell Medical Index of patients stabilized on LAM with those on methadone. 1972 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Adult; Blood Glucose; Cornell Medical Index; Electroencephalography; Female; Humans; Male; Methadone; Methadyl Acetate; Substance-Related Disorders	1976
Actions and addiction liabilities of alpha-acetylmethadols in man. 1952 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Adult; Drug Administration Schedule; Humans; Male; Methadone; Methadyl Acetate; Miotics; Morphine Dependence; Substance Withdrawal Syndrome; Substance-Related Disorders	1976
LAAM and LAAM metabolites: plasma levels in patients. Summary progress report. 1975 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Humans; Methadone; Methadyl Acetate; Substance-Related Disorders; Time Factors	1976
Pharmacodynamics of LAAM in man: plasma levels of LAAM and its metabolites following acute and chronic administration in man (fourth and sixth quarter progress reports). 1974-5 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Drug Administration Schedule; Humans; Kinetics; Male; Methadone; Methadyl Acetate; Substance-Related Disorders	1976
Disposition of acetylmethadol in relation to pharmacological activity. 1975 [proceedings]. NIDA research monograph, 1976, Issue:8 Topics: Adult; Half-Life; Humans; Male; Methadone; Methadyl Acetate; Pupil; Substance-Related Disorders; Time Factors	1976
Interactions of narcotics, narcotic antagonists, and ethanol during acute, chronic, and withdrawal states. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Alcohol Drinking; Animals; Animals, Newborn; Dextrorphan; Drug Interactions; Ethanol; Humans; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1976
On the role of chemotherapy in the treatment of heroin addiction. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Heroin Dependence; Humans; Methadone; Methadyl Acetate; Motivation; Naloxone; Naltrexone; Substance-Related Disorders	1975
Patient deaths in a narcotic antagonist (naltrexone) and l-alpha-acetylmethadol program. The American journal of drug and alcohol abuse, 1975, Volume: 2, Issue:3-4 Topics: Adult; Heroin Dependence; Homicide; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Naltrexone; Psychotropic Drugs; Substance-Related Disorders; Suicide	1975
NIDA's Medication Development Program--1989. NIDA research monograph, 1989, Volume: 95 Topics: Acquired Immunodeficiency Syndrome; Brain; Cocaine; Drug and Narcotic Control; Female; Heroin Dependence; Humans; Infant, Newborn; Methadone; Methadyl Acetate; Naltrexone; Pregnancy; Psychotropic Drugs; Research Support as Topic; Risk Factors; Substance Abuse, Intravenous; Substance-Related Disorders	1989