methadone has been researched along with Weight Gain in 14 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone maintenance treatment (MMT) is an important treatment tool for the opioid epidemic." | 6.58 | Double jeopardy: a review of weight gain and weight management strategies for psychotropic medication prescribing during methadone maintenance treatment. ( Antoine, DG; Huhn, AS; Schlienz, NJ; Speed, TJ; Sweeney, MM, 2018) |
| "Newborns who are prenatally exposed to methadone are at risk for neonatal abstinence syndrome and the associated excess weight loss and poor weight gain." | 5.27 | Randomized Clinical Trial of Standard- Versus High-Calorie Formula for Methadone-Exposed Infants: A Feasibility Study. ( Baker, R; Bogen, DL; Cohlan, B; Hanusa, BH; Medoff-Cooper, B, 2018) |
| "These analyses corroborate evidence of weight gain with methadone treatment but did not observe a sex-based disparity in weight gain with methadone or buprenorphine treatment for OUD." | 5.22 | Sex differences in weight gain during medication-based treatment for opioid use disorder: A meta-analysis and retrospective analysis of clinical trial data. ( Dennis, E; Hu, L; Johnson, A; Kroll, D; Manza, P; McPherson, KL; Tai, B; Volkow, ND, 2022) |
| " However, data suggest the potential for significant weight gain during methadone treatment and little is known about weight change during buprenorphine treatment." | 4.31 | Weight change in a national cohort of U.S. Military Veterans engaged in medication treatment for opioid use disorder. ( Carr, MM; Cave, S; Martino, S; Masheb, R; Midboe, AM; Wolkowicz, NR, 2023) |
| "Despite the clear efficacy of methadone for opioid dependence, one less desirable phenomenon associated with methadone may be weight gain." | 3.81 | Increases in body mass index following initiation of methadone treatment. ( Fenn, JM; Laurent, JS; Sigmon, SC, 2015) |
| "Besides significant reduction in heroin consumption, weight gain is an accompanying phenomenon during methadone maintenance treatment." | 3.78 | [Weight changes of patients in methadone maintenance treatment during four years period]. ( Okruhlica, Ĺ; Slezáková, S, 2012) |
| "Methadone maintenance treatment (MMT) is an important treatment tool for the opioid epidemic." | 2.58 | Double jeopardy: a review of weight gain and weight management strategies for psychotropic medication prescribing during methadone maintenance treatment. ( Antoine, DG; Huhn, AS; Schlienz, NJ; Speed, TJ; Sweeney, MM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Manza, P | 1 |
| Kroll, D | 1 |
| McPherson, KL | 1 |
| Johnson, A | 1 |
| Dennis, E | 1 |
| Hu, L | 1 |
| Tai, B | 1 |
| Volkow, ND | 1 |
| Carr, MM | 1 |
| Wolkowicz, NR | 1 |
| Cave, S | 1 |
| Martino, S | 1 |
| Masheb, R | 1 |
| Midboe, AM | 1 |
| Kaplan, HC | 1 |
| Kuhnell, P | 1 |
| Walsh, MC | 1 |
| Crowley, M | 1 |
| McClead, R | 1 |
| Wexelblatt, S | 1 |
| Ford, S | 1 |
| Provost, LP | 1 |
| Lannon, C | 1 |
| Macaluso, M | 1 |
| Bogen, DL | 1 |
| Hanusa, BH | 1 |
| Baker, R | 1 |
| Medoff-Cooper, B | 1 |
| Cohlan, B | 1 |
| Schlienz, NJ | 1 |
| Huhn, AS | 1 |
| Speed, TJ | 1 |
| Sweeney, MM | 1 |
| Antoine, DG | 1 |
| Fenn, JM | 1 |
| Laurent, JS | 1 |
| Sigmon, SC | 2 |
| Okruhlica, L | 2 |
| Slezáková, S | 2 |
| Staub, D | 1 |
| Vargo, MA | 1 |
| Leveille, TL | 1 |
| Szpanowska-Wohn, A | 1 |
| Kolarzyk, E | 1 |
| Pach, D | 1 |
| Targosz, D | 1 |
| Kábrt, J | 1 |
| Wilczek, H | 1 |
| Svobodová, J | 1 |
| Haluzík, M | 1 |
| Kotrlíková, E | 1 |
| Robinson, SE | 1 |
| Wallace, MJ | 1 |
| Gundersen, R | 1 |
2 reviews available for methadone and Weight Gain
| Article | Year |
|---|---|
Sex differences in weight gain during medication-based treatment for opioid use disorder: A meta-analysis and retrospective analysis of clinical trial data.
Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Male; Methadone; Opiate Substitution Treatment; O | 2022 |
Double jeopardy: a review of weight gain and weight management strategies for psychotropic medication prescribing during methadone maintenance treatment.
Topics: Body Weight Maintenance; Diagnosis, Dual (Psychiatry); Humans; Methadone; Narcotics; Opiate Substitu | 2018 |
1 trial available for methadone and Weight Gain
| Article | Year |
|---|---|
Randomized Clinical Trial of Standard- Versus High-Calorie Formula for Methadone-Exposed Infants: A Feasibility Study.
Topics: Double-Blind Method; Energy Intake; Feasibility Studies; Female; Humans; Infant Formula; Infant, New | 2018 |
11 other studies available for methadone and Weight Gain
| Article | Year |
|---|---|
Weight change in a national cohort of U.S. Military Veterans engaged in medication treatment for opioid use disorder.
Topics: Analgesics, Opioid; Buprenorphine; Humans; Methadone; Opiate Substitution Treatment; Opioid-Related | 2023 |
Orchestrated Testing of Formula Type to Reduce Length of Stay in Neonatal Abstinence Syndrome.
Topics: Energy Intake; Female; Humans; Infant Formula; Infant, Newborn; Lactose; Length of Stay; Methadone; | 2020 |
Increases in body mass index following initiation of methadone treatment.
Topics: Adult; Body Mass Index; Body Weight; Female; Humans; Male; Methadone; Middle Aged; Opiate Substituti | 2015 |
Additive burdens of malnutrition, poverty, and substance abuse.
Topics: Analgesics, Opioid; Blood Glucose; Cost of Illness; Feeding Behavior; Health Behavior; Health Promot | 2016 |
[Weight gain among the patients in methadone maintenance program as come-back to population norm].
Topics: Adult; Body Mass Index; Female; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Weight | 2008 |
Tackling a weighty issue.
Topics: Adult; Body Mass Index; Florida; Humans; Methadone; Overweight; Patient Education as Topic; Program | 2009 |
[Weight changes of patients in methadone maintenance treatment during four years period].
Topics: Adult; Female; Heroin Dependence; Humans; Male; Methadone; Opiate Substitution Treatment; Weight Gai | 2012 |
[Nutritional status of opiate-dependent persons before and during methadone maintenance therapy].
Topics: Adult; Body Composition; Body Mass Index; Body Size; Female; Humans; Male; Methadone; Middle Aged; N | 2004 |
[Nutritional status of drug addicts in a methadone program].
Topics: Adult; Anthropometry; Blood Chemical Analysis; Female; Humans; Male; Methadone; Nutritional Status; | 1999 |
Effect of perinatal buprenorphine exposure on development in the rat.
Topics: Animals; Animals, Newborn; Buprenorphine; Drinking; Eating; Female; Growth; Litter Size; Methadone; | 2001 |
[Methadone and thyroid disorders].
Topics: Humans; Hypothyroidism; Methadone; Narcotics; Obesity; Opioid-Related Disorders; Weight Gain | 2001 |