Page last updated: 2024-10-30

methadone and Takotsubo Cardiomyopathy

methadone has been researched along with Takotsubo Cardiomyopathy in 3 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Takotsubo Cardiomyopathy: A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.

Research Excerpts

ExcerptRelevanceReference
"Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning or reversible midventricular systolic dysfunction."5.37Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal. ( Bhat, T; Duvvuri, S; Jun, CH; Khattri, S; Lafferty, J; Saiful, FB; Teli, S, 2011)
"BACKGROUND Stress cardiomyopathy (SCM) is a transient dysfunction of the left ventricle due to physical or emotional triggers that produces a range of electrocardiogram (ECG) changes."1.51Diffuse Deep T-Wave Inversions Following a Generalized Seizure. ( Oleynick, C; Prosperi-Porta, G, 2019)
"Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning or reversible midventricular systolic dysfunction."1.37Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal. ( Bhat, T; Duvvuri, S; Jun, CH; Khattri, S; Lafferty, J; Saiful, FB; Teli, S, 2011)
"We describe the first case of stress cardiomyopathy secondary to a drug-drug interaction."1.36First case of stress cardiomyopathy as a result of methadone withdrawal secondary to drug-drug interaction. ( Lemesle, F; Nicola, W; Pierre Jonville-Béra, A, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prosperi-Porta, G1
Oleynick, C1
Lemesle, F2
Nicola, W1
Pierre Jonville-Béra, A1
Saiful, FB1
Lafferty, J1
Jun, CH1
Teli, S1
Duvvuri, S1
Khattri, S1
Bhat, T1

Other Studies

3 other studies available for methadone and Takotsubo Cardiomyopathy

ArticleYear
Diffuse Deep T-Wave Inversions Following a Generalized Seizure.
    The American journal of case reports, 2019, Oct-26, Volume: 20

    Topics: Adult; Delayed Diagnosis; Diagnosis, Differential; Electrocardiography; Female; Humans; Methadone; P

2019
First case of stress cardiomyopathy as a result of methadone withdrawal secondary to drug-drug interaction.
    The American journal of emergency medicine, 2010, Volume: 28, Issue:3

    Topics: Adult; Drug Interactions; Echocardiography; Electrocardiography; Humans; Male; Methadone; Naltrexone

2010
Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal.
    Reviews in cardiovascular medicine, 2011, Volume: 12, Issue:3

    Topics: Analgesics, Opioid; Coronary Angiography; Drug Overdose; Echocardiography; Electrocardiography; Huma

2011