Page last updated: 2024-10-30

methadone and Tachycardia, Ventricular

methadone has been researched along with Tachycardia, Ventricular in 4 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"We present a case of seizure activity in a woman in whom EKG led to a diagnosis of intermittent monomorphic and polymorphic ventricular tachycardia (torsades de pointes), highlighting the need for careful consideration of alternative causes of seizures, even in patients with known epilepsy."1.46Ventricular tachycardia and prolonged QT interval presenting as seizure-like activity. ( Mitchell, SH; Morris, SC; Wentlandt, M, 2017)
"We describe 2 cases of symptomatic ventricular tachycardia associated with prolonged QT interval."1.35Ritonavir-boosted atazanavir, methadone, and ventricular tachycardia: 2 case reports. ( Gallagher, DP; Kieran, J; Lambert, J; Mahon, N; Mallon, PW; Sheehan, G, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ryan, K1
Benz, P1
Zosel, A1
Farkas, A1
Theobald, J1
Wentlandt, M1
Morris, SC1
Mitchell, SH1
Gallagher, DP1
Kieran, J1
Sheehan, G1
Lambert, J1
Mahon, N1
Mallon, PW1
Østvold, C1
Topper, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label, Randomised Pilot Study Comparing the Efficacy, Safety and Tolerability of Raltegravir With Protease Inhibitor-based Therapy in Treatment-naïve, HIV/Hepatitis C Co-infected Injecting Drug Users Receiving Methadone[NCT01105611]Phase 440 participants (Anticipated)Interventional2010-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for methadone and Tachycardia, Ventricular

ArticleYear
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
    Cardiovascular toxicology, 2022, Volume: 22, Issue:9

    Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long

2022
Ventricular tachycardia and prolonged QT interval presenting as seizure-like activity.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:5

    Topics: Adult; Alcoholism; Anti-Arrhythmia Agents; Anticonvulsants; Diuretics; Electrocardiography; Emergenc

2017
Ritonavir-boosted atazanavir, methadone, and ventricular tachycardia: 2 case reports.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Aug-01, Volume: 47, Issue:3

    Topics: Adult; Atazanavir Sulfate; Drug Therapy, Combination; Electrocardiography; HIV Infections; HIV Prote

2008
[Methadone-induced heart arrhythmia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2005, Aug-11, Volume: 125, Issue:15

    Topics: Adult; Electrocardiography; Fatal Outcome; Female; Humans; Long QT Syndrome; Male; Methadone; Middle

2005