Page last updated: 2024-10-30

methadone and Syncope

methadone has been researched along with Syncope in 5 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
"Methadone is associated with QT prolongation and higher reporting of syncope in a population of heroin addicts."7.74Syncope and QT prolongation among patients treated with methadone for heroin dependence in the city of Copenhagen. ( Ege, P; Fanoe, S; Hvidt, C; Jensen, GB, 2007)
"Methadone is associated with QT prolongation and higher reporting of syncope in a population of heroin addicts."3.74Syncope and QT prolongation among patients treated with methadone for heroin dependence in the city of Copenhagen. ( Ege, P; Fanoe, S; Hvidt, C; Jensen, GB, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katz, DF1
Varosy, PD1
Masoudi, FA1
Krantz, MJ1
Mehler, PS1
Rademacher, S1
Dietz, R1
Haverkamp, W1
Chatterjee, B1
Bürgi, U1
Fanoe, S1
Hvidt, C1
Ege, P1
Jensen, GB1

Other Studies

5 other studies available for methadone and Syncope

ArticleYear
Syncope: a tale of two triggers.
    JAMA internal medicine, 2013, Sep-09, Volume: 173, Issue:16

    Topics: Bradycardia; Dose-Response Relationship, Drug; Electrocardiography; Humans; Male; Methadone; Middle

2013
Synthetic opioids and QT prolongation.
    Archives of internal medicine, 2003, Jul-14, Volume: 163, Issue:13

    Topics: Heroin Dependence; Humans; Long QT Syndrome; Methadone; Narcotics; Syncope

2003
QT prolongation and syncope with methadone, doxepin, and a beta-blocker.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Anxiety Disorders; Doxepin; Electrocardiography; Humans; Long QT

2005
Syncope of a drug addict - a special case.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95, Issue:10

    Topics: Adult; Female; Heroin Dependence; Humans; Long QT Syndrome; Methadone; Narcotics; Syncope; Torsades

2006
Syncope and QT prolongation among patients treated with methadone for heroin dependence in the city of Copenhagen.
    Heart (British Cardiac Society), 2007, Volume: 93, Issue:9

    Topics: Adult; Buprenorphine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Electrocardiography

2007