Page last updated: 2024-10-30

methadone and Smoking Cessation

methadone has been researched along with Smoking Cessation in 67 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Smoking Cessation: Discontinuing the habit of SMOKING.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to evaluate the efficacy of varenicline directly observed therapy (DOT) on varenicline adherence and smoking cessation rates among smokers with opioid use disorder (OUD) receiving methadone treatment."9.41Effect of varenicline directly observed therapy versus varenicline self-administered therapy on varenicline adherence and smoking cessation in methadone-maintained smokers: a randomized controlled trial. ( Adams, TR; Arnsten, JH; Nahvi, S; Ning, Y; Zhang, C, 2021)
"We test, using a three-group randomized design, the efficacy of varenicline versus placebo, in comparison with nicotine replacement therapy (NRT) that combines nicotine patch prescription plus ad libitum nicotine rescue, for smoking cessation."9.17Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial. ( Anderson, BJ; Audet, D; Caviness, CM; Kurth, ME; Olson, J; Stein, MD, 2013)
"To determine predictors of smoking cessation duration in a randomized clinical trial, we assigned participants to nicotine patch (8-12 weeks) plus either (a) a baseline tailored brief motivational intervention, a quit date behavioral skills counseling session, and a relapse prevention follow-up session, or (b) brief advice using the National Cancer Institute's 4A's model."9.12Smoking cessation patterns in methadone-maintained smokers. ( Anderson, BJ; Niaura, R; Stein, MD, 2007)
"To test, in combination with the nicotine patch, the incremental efficacy of a maximal, tailored behavioral treatment over a minimal treatment for smoking cessation."9.12A smoking cessation intervention for the methadone-maintained. ( Anderson, BJ; Anthony, JL; Herman, DS; Niaura, R; Stein, MD; Weinstock, MC, 2006)
"The relationship between tobacco and illicit drug use was examined among 166 methadone-maintained persons participating in a smoking cessation intervention."9.10Using latent-variable models to analyze smoking cessation clinical trial data: an example among the methadone maintained. ( Frosch, DL; Shoptaw, S; Stein, JA, 2002)
"To evaluate relapse prevention (relapse prevention) and contingency management (contingency management) for optimizing smoking cessation outcomes using nicotine replacement therapy for methadone-maintained tobacco smokers."9.10Smoking cessation in methadone maintenance. ( Frosch, D; Jarvik, ME; Ling, W; Nahom, D; Rawson, RA; Rotheram-Fuller, E; Shoptaw, S; Yang, X, 2002)
"Individuals in methadone maintenance treatment are motivated to quit smoking and are interested in smoking cessation treatment."8.86Smoking cessation interventions among individuals in methadone maintenance: a brief review. ( Barr, AM; Greaves, L; Johnson, JL; Khara, M; Okoli, CT; Procyshyn, RM, 2010)
"Over 80% of people in methadone treatment smoke cigarettes, and existing smoking cessation interventions have been minimally effective."7.81Determining Smoking Cessation Related Information, Motivation, and Behavioral Skills among Opiate Dependent Smokers in Methadone Treatment. ( Bernstein, SL; Cooperman, NA; Richter, KP; Steinberg, ML; Williams, JM, 2015)
"Smoking cessation treatment service is concerned to be a critical element in methadone maintenance treatment (MMT) in order to diminish the effect of smoke on health outcomes."7.81Motivation for smoking cessation among drug-using smokers under methadone maintenance treatment in Vietnam. ( Do, HP; Dunne, M; Latkin, C; Nguyen, LH; Nguyen, NP; Phan, HT; Tran, BX, 2015)
"The need for research to develop and test tailored interventions for this population is highlighted, as is the need for methadone services and staff to facilitate client smoking cessation."7.78Smoking cessation among Australian methadone clients: prevalence, characteristics and a need for action. ( Bartlem, K; Bowman, J; Colyvas, K; Walsh, RA; Wiggers, J; Wye, P, 2012)
"To report the potential clinically significant pharmacokinetic interaction that may result from smoking cessation in patients on methadone maintenance therapy."7.77Methadone toxicity due to smoking cessation--a case report on the drug-drug interaction involving cytochrome P450 isoenzyme 1A2. ( Kolluru, S; Molina, C; Nguyen, T; Speake, J; Wahawisan, J, 2011)
"Our data show a higher level of nicotine dependence and depression, and greater readiness to change among women smokers in methadone maintenance programmes compared to women smokers attending primary care clinics."7.76Nicotine dependence and depression among women smokers on methadone maintenance. ( Arnold, S; Gandhi, D; Joshi, A; Khanna, N; Sadaphal, S; Stewart, D, 2010)
"This study was aimed at assessing feasibility and patient acceptance of an interactive educational module of a multi-component smoking cessation counseling computer program for former illicit drug users treated in an outpatient methadone clinic."7.74Feasibility of promoting smoking cessation among methadone users using multimedia computer-assisted education. ( Cha, E; Finkelstein, J; Lapshin, O, 2008)
"There was described and discussed a case of methadone maintenance participant, former polydrug abuser, who has received a standard treatment with bupropion SR for smoking cessation."7.73[Bupropion in cigarettes smoking cessation by former polydrug user participating in methadone maintenance programme]. ( Habrat, B; Steinbarth-Chmielewska, K, 2005)
"Little is known about how well methadone programs address smoking cessation."7.73Addressing smoking cessation in methadone programs. ( Alford, DP; Horton, NJ; Olsen, Y; Saitz, R, 2005)
" In the 30 days before the survey, respondents reported that their clinics provided the following services to at least one patient: 73 percent provided brief advice to quit, 18 percent offered individual or group smoking cessation counseling, and 12 percent prescribed nicotine replacement therapy."7.72Smoking cessation services in U.S. methadone maintenance facilities. ( Ahluwalia, JS; Choi, WS; Harris, KJ; McCool, RM; Richter, KP, 2004)
"Several studies have shown high levels of interest in smoking cessation among methadone maintained heroin users, yet little is known about how to intervene most effectively with this population."7.71Optimizing smoking cessation outcomes among the methadone maintained. ( Frosch, DL; Nahom, D; Shoptaw, S, 2002)
" Because a history of depression has been shown in other populations to complicate cessation efforts, the relationship between depression and nicotine dependence was tested in 726 methadone patients."7.69Nicotine dependence and depression among methadone maintenance patients. ( Brown, LS; Lin, MM; Meyer, TJ, 1996)
"Methadone maintenance treatment (MMT) patients have an exceedingly high prevalence of tobacco use, and interventions that have been specifically developed for this vulnerable subpopulation have struggled to attain even modest rates of cessation."6.79Early quit days among methadone-maintained smokers in a smoking cessation trial. ( Anderson, BJ; Caviness, CM; de Dios, MA; Stein, MD, 2014)
"Nicotine use disorder is highly prevalent among methadone maintenance patients with its tobacco-related problems."6.58Smoking Cessation Among Methadone-Maintained Patients: A Meta-Analysis. ( Hoong, MC; Joyce, YC; Loh, HS; Yee, A, 2018)
"Over 85% of opioid-dependent individuals in methadone treatment smoke cigarettes; however, smoking cessation interventions are minimally effective in this population."5.27Pilot Study of a Tailored Smoking Cessation Intervention for Individuals in Treatment for Opioid Dependence. ( Bernstein, SL; Cooperman, NA; Lu, SE; Richter, KP; Williams, JM, 2018)
"To test the efficacy and safety of varenicline as an aid to smoking cessation in methadone-maintained smokers."5.19Varenicline efficacy and safety among methadone maintained smokers: a randomized placebo-controlled trial. ( Arnsten, JH; Nahvi, S; Ning, Y; Richter, KP; Segal, KS, 2014)
"Tobacco cessation medication adherence is one of the few factors shown to improve smoking cessation rates among methadone-maintained smokers, but interventions to improve adherence to smoking cessation medications have not yet been tested among methadone treatment patients."5.19Rationale and design of a randomized controlled trial of varenicline directly observed therapy delivered in methadone clinics. ( Arnsten, JH; Litwin, AH; Nahvi, S; Segal, KS, 2014)
"We test, using a three-group randomized design, the efficacy of varenicline versus placebo, in comparison with nicotine replacement therapy (NRT) that combines nicotine patch prescription plus ad libitum nicotine rescue, for smoking cessation."5.17Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial. ( Anderson, BJ; Audet, D; Caviness, CM; Kurth, ME; Olson, J; Stein, MD, 2013)
"This study evaluated the efficacy of a contingency management (CM) intervention to promote smoking cessation in methadone-maintained patients."5.13Voucher-based contingent reinforcement of smoking abstinence among methadone-maintained patients: a pilot study. ( Dunn, KE; Heil, SH; Higgins, ST; Sigmon, SC; Thomas, CS, 2008)
"To test, in combination with the nicotine patch, the incremental efficacy of a maximal, tailored behavioral treatment over a minimal treatment for smoking cessation."5.12A smoking cessation intervention for the methadone-maintained. ( Anderson, BJ; Anthony, JL; Herman, DS; Niaura, R; Stein, MD; Weinstock, MC, 2006)
"To determine predictors of smoking cessation duration in a randomized clinical trial, we assigned participants to nicotine patch (8-12 weeks) plus either (a) a baseline tailored brief motivational intervention, a quit date behavioral skills counseling session, and a relapse prevention follow-up session, or (b) brief advice using the National Cancer Institute's 4A's model."5.12Smoking cessation patterns in methadone-maintained smokers. ( Anderson, BJ; Niaura, R; Stein, MD, 2007)
"Between February 2002 and May 2004 we recruited 383 smokers from 5 methadone maintenance programs for a randomized trial of nicotine replacement plus behavioral treatment versus nicotine replacement alone for smoking cessation."5.11Respiratory symptom relief related to reduction in cigarette use. ( Anderson, BJ; Herman, DS; Stein, MD; Weinstock, MC, 2005)
"To evaluate relapse prevention (relapse prevention) and contingency management (contingency management) for optimizing smoking cessation outcomes using nicotine replacement therapy for methadone-maintained tobacco smokers."5.10Smoking cessation in methadone maintenance. ( Frosch, D; Jarvik, ME; Ling, W; Nahom, D; Rawson, RA; Rotheram-Fuller, E; Shoptaw, S; Yang, X, 2002)
"The relationship between tobacco and illicit drug use was examined among 166 methadone-maintained persons participating in a smoking cessation intervention."5.10Using latent-variable models to analyze smoking cessation clinical trial data: an example among the methadone maintained. ( Frosch, DL; Shoptaw, S; Stein, JA, 2002)
" This review summarizes existing knowledge about smoking cessation treatments for pregnant women on buprenorphine or methadone, the two forms of medication-assisted treatment for opioid use disorder indicated for prenatal use."4.91Treating tobacco use disorder in pregnant women in medication-assisted treatment for an opioid use disorder: a systematic review. ( Akerman, SC; Blunt, HB; Brunette, MF; Goodman, DJ; Green, AI; Heil, SH, 2015)
" In this commentary, we briefly summarize the extant literature on pharmacotherapies in opioid-maintained smokers and contribute new data investigating the contribution of bupropion on smoking outcomes in 81 methadone- and buprenorphine-maintained participants from two randomized trials of financial incentives for smoking cessation."4.91Are Pharmacotherapies Ineffective in Opioid-Dependent Smokers? Reflections on the Scientific Literature and Future Directions. ( Miller, ME; Sigmon, SC, 2015)
"Individuals in methadone maintenance treatment are motivated to quit smoking and are interested in smoking cessation treatment."4.86Smoking cessation interventions among individuals in methadone maintenance: a brief review. ( Barr, AM; Greaves, L; Johnson, JL; Khara, M; Okoli, CT; Procyshyn, RM, 2010)
" This method has found smoking cessation and methadone maintenance to be highly cost-effective health care programs."4.80The cost-effectiveness of substance abuse treatment. ( Barnett, PG, 1999)
"Pregnant smokers recruited to participate in a placebo-controlled trial of bupropion for smoking cessation provided a blood sample for measurement of NMR."3.96Pregnant Smokers Receiving Opioid Agonist Therapy Have an Elevated Nicotine Metabolite Ratio: A Replication Study. ( Hand, D; Kranzler, HR; Lynch, KG; Oncken, C; Schnoll, R; Tyndale, RF; Washio, Y; Zindel, LR, 2020)
"Smoking cessation treatment service is concerned to be a critical element in methadone maintenance treatment (MMT) in order to diminish the effect of smoke on health outcomes."3.81Motivation for smoking cessation among drug-using smokers under methadone maintenance treatment in Vietnam. ( Do, HP; Dunne, M; Latkin, C; Nguyen, LH; Nguyen, NP; Phan, HT; Tran, BX, 2015)
"Over 80% of people in methadone treatment smoke cigarettes, and existing smoking cessation interventions have been minimally effective."3.81Determining Smoking Cessation Related Information, Motivation, and Behavioral Skills among Opiate Dependent Smokers in Methadone Treatment. ( Bernstein, SL; Cooperman, NA; Richter, KP; Steinberg, ML; Williams, JM, 2015)
" Methadone patients will likely experience little harm and a great deal of benefit from treatment with varenicline for smoking cessation."3.79Low incidence of adverse events following varenicline initiation among opioid dependent smokers with comorbid psychiatric illness. ( Arnsten, JH; Bernstein, SL; Nahvi, S; Richter, KP; Wu, B, 2013)
"The need for research to develop and test tailored interventions for this population is highlighted, as is the need for methadone services and staff to facilitate client smoking cessation."3.78Smoking cessation among Australian methadone clients: prevalence, characteristics and a need for action. ( Bartlem, K; Bowman, J; Colyvas, K; Walsh, RA; Wiggers, J; Wye, P, 2012)
"To report the potential clinically significant pharmacokinetic interaction that may result from smoking cessation in patients on methadone maintenance therapy."3.77Methadone toxicity due to smoking cessation--a case report on the drug-drug interaction involving cytochrome P450 isoenzyme 1A2. ( Kolluru, S; Molina, C; Nguyen, T; Speake, J; Wahawisan, J, 2011)
"Our data show a higher level of nicotine dependence and depression, and greater readiness to change among women smokers in methadone maintenance programmes compared to women smokers attending primary care clinics."3.76Nicotine dependence and depression among women smokers on methadone maintenance. ( Arnold, S; Gandhi, D; Joshi, A; Khanna, N; Sadaphal, S; Stewart, D, 2010)
" A carbon monoxide longitudinal data set in a smoking cessation study is used for illustration."3.73Assessing missing data assumptions in longitudinal studies: an example using a smoking cessation trial. ( Shoptaw, S; Yang, X, 2005)
" In multivariate analyses, lower nicotine dependence, prior use of smoking cessation pharmacotherapy, and lower methadone dose were associated with being in the preparation stage."3.73Cigarette smoking and interest in quitting in methadone maintenance patients. ( Arnsten, J; Li, X; Modali, L; Nahvi, S; Richter, K, 2006)
"There was described and discussed a case of methadone maintenance participant, former polydrug abuser, who has received a standard treatment with bupropion SR for smoking cessation."3.73[Bupropion in cigarettes smoking cessation by former polydrug user participating in methadone maintenance programme]. ( Habrat, B; Steinbarth-Chmielewska, K, 2005)
" In the 30 days before the survey, respondents reported that their clinics provided the following services to at least one patient: 73 percent provided brief advice to quit, 18 percent offered individual or group smoking cessation counseling, and 12 percent prescribed nicotine replacement therapy."3.72Smoking cessation services in U.S. methadone maintenance facilities. ( Ahluwalia, JS; Choi, WS; Harris, KJ; McCool, RM; Richter, KP, 2004)
"Several studies have shown high levels of interest in smoking cessation among methadone maintained heroin users, yet little is known about how to intervene most effectively with this population."3.71Optimizing smoking cessation outcomes among the methadone maintained. ( Frosch, DL; Nahom, D; Shoptaw, S, 2002)
"We describe the degree of nicotine addiction and readiness to quit smoking among people with a history of injection drug use, comparing those in a methadone maintenance treatment program (MMTP) with active illicit drug injectors in a needle exchange program (NEP)."3.71Interest in smoking cessation among injection drug users. ( Clarke, JG; Gogineni, A; McGarry, KA; Stein, MD, 2001)
" Because a history of depression has been shown in other populations to complicate cessation efforts, the relationship between depression and nicotine dependence was tested in 726 methadone patients."3.69Nicotine dependence and depression among methadone maintenance patients. ( Brown, LS; Lin, MM; Meyer, TJ, 1996)
"Methadone maintenance treatment (MMT) patients have an exceedingly high prevalence of tobacco use, and interventions that have been specifically developed for this vulnerable subpopulation have struggled to attain even modest rates of cessation."2.79Early quit days among methadone-maintained smokers in a smoking cessation trial. ( Anderson, BJ; Caviness, CM; de Dios, MA; Stein, MD, 2014)
"Nicotine plasma levels were highest on the cigarette smoking day (P < 0."2.74Methadone-nicotine interactions in methadone maintenance treatment patients. ( Brands, B; Elkader, AK; Selby, P; Sproule, BA, 2009)
" Participants smoked a greater proportion of cigarettes in their first 2-hr block after methadone dosing (M = 0."2.73Patterns of smoking and methadone dose in drug treatment patients. ( Catley, D; Cox, LS; Grobe, J; Hall, S; Hamilton, AK; Richter, KP, 2007)
"Nicotine use disorder is highly prevalent among methadone maintenance patients with its tobacco-related problems."2.58Smoking Cessation Among Methadone-Maintained Patients: A Meta-Analysis. ( Hoong, MC; Joyce, YC; Loh, HS; Yee, A, 2018)
"Methadone is a long-acting opioid agonist that is frequently prescribed as a treatment for opioid addiction."2.52Methadone's effect on nAChRs--a link between methadone use and smoking? ( Salminen, O; Talka, R; Tuominen, RK, 2015)
"Although individuals in substance use disorders (SUD) treatment continue to smoke at high rates, regulatory, policy and programming changes promoting tobacco cessation are being implemented and some patients quit successfully."1.46Quitting smoking during substance use disorders treatment: Patient and treatment-related variables. ( Campbell, BK; Guydish, J; Le, T; Tajima, B, 2017)
"Five methadone maintenance treatment centers."1.33Nicotine replacement therapy: patterns of use after a quit attempt among methadone-maintained smokers. ( Anderson, BJ; Niaura, R; Stein, MD, 2006)
"When methadone and puffs were concurrently available, an increase in methadone's price decreased puff consumption, and demand for methadone was less elastic than when puffs were not concurrently available."1.33Methadone and nicotine self-administration in humans: a behavioral economic analysis. ( Cowan, K; Hursh, S; Martinetti, MP; Meisch, RA; Spiga, R, 2005)
"Most substance abuse treatment facilities do not routinely treat cigarette smoking even though most of their clients smoke and many will die from tobacco-related illness."1.33Good and bad times for treating cigarette smoking in drug treatment. ( Richter, KP, 2006)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (11.94)18.2507
2000's30 (44.78)29.6817
2010's26 (38.81)24.3611
2020's3 (4.48)2.80

Authors

AuthorsStudies
Ware, OD1
Sweeney, MM1
Cunningham, C1
Umbricht, A1
Stitzer, M2
Dunn, KE2
Kranzler, HR1
Washio, Y1
Zindel, LR1
Lynch, KG1
Hand, D1
Tyndale, RF1
Oncken, C1
Schnoll, R1
Nahvi, S6
Adams, TR1
Ning, Y2
Zhang, C1
Arnsten, JH4
Yee, A1
Hoong, MC1
Joyce, YC1
Loh, HS1
Cooperman, NA2
Lu, SE1
Richter, KP11
Bernstein, SL3
Williams, JM2
Zirakzadeh, A1
Shuman, C1
Stauter, E1
Hays, JT1
Ebbert, JO1
Stein, MD11
Caviness, CM3
Kurth, ME1
Audet, D2
Olson, J1
Anderson, BJ10
Segal, KS3
Litwin, AH1
de Dios, MA2
Steinberg, ML1
Akerman, SC1
Brunette, MF1
Green, AI1
Goodman, DJ1
Blunt, HB1
Heil, SH2
Griffin, JL1
Miller, ME1
Sigmon, SC2
Talka, R1
Tuominen, RK1
Salminen, O1
Tran, BX1
Nguyen, LH1
Do, HP1
Nguyen, NP1
Phan, HT1
Dunne, M1
Latkin, C1
Caviness, C1
Grimone, K1
Bailey, GL1
Winhusen, T1
Theobald, J1
Lewis, D1
Campbell, BK2
Le, T1
Tajima, B2
Guydish, J2
Finkelstein, J1
Lapshin, O1
Cha, E1
Thomas, CS1
Higgins, ST1
Elkader, AK1
Brands, B1
Selby, P1
Sproule, BA1
Okoli, CT1
Khara, M1
Procyshyn, RM1
Johnson, JL1
Barr, AM1
Greaves, L1
Li, L1
Liu, Y1
Zhang, Y1
Beveridge, TJ1
Zhou, W1
Khanna, N1
Arnold, S1
Sadaphal, S1
Joshi, A1
Stewart, D1
Gandhi, D1
Wahawisan, J1
Kolluru, S1
Nguyen, T1
Molina, C1
Speake, J1
Reid, MS1
Jiang, H1
Fallon, B1
Sonne, S1
Rinaldi, P1
Turrigiano, E1
Arfken, C1
Robinson, J1
Rotrosen, J1
Nunes, EV1
Bowman, J1
Wiggers, J1
Colyvas, K1
Wye, P1
Walsh, RA1
Bartlem, K1
Kulaga, A1
Zavala, R1
Brown, LS2
Bostrom, A1
Ziedonis, D1
Chan, M1
Stanton, CA1
Niaura, R5
Stein, M1
Tuten, M1
Fitzsimons, H1
Chisolm, MS1
Nuzzo, PA1
Jones, HE1
Wu, B1
Frosch, DL3
Stein, JA1
Shoptaw, S5
Rotheram-Fuller, E1
Yang, X2
Frosch, D1
Nahom, D2
Jarvik, ME2
Rawson, RA2
Ling, W2
McCool, RM4
Okuyemi, KS1
Mayo, MS1
Ahluwalia, JS5
Paschall Richter, K1
Spiga, R2
Martinetti, MP1
Meisch, RA1
Cowan, K1
Hursh, S1
Choi, WS1
Harris, KJ1
Shadel, WG1
Herman, DS3
Bishop, S1
Lassor, JA1
Weinstock, M1
Anthony, JL3
Hayaki, J1
Olsen, Y1
Alford, DP1
Horton, NJ1
Saitz, R1
Baran-Furga, H1
Chmielewska, K1
Bogucka-Bonikowska, A1
Habrat, B2
Kostowski, W1
Bienkowski, P1
Weinstock, MC3
Shah, NG1
Galai, N1
Celentano, DD1
Vlahov, D1
Strathdee, SA1
Catley, D2
Hall, M1
Richter, K1
Li, X1
Modali, L1
Arnsten, J1
Steinbarth-Chmielewska, K1
Hamilton, AK1
Hall, S1
Cox, LS1
Grobe, J1
Stark, MJ1
Meyer, TJ1
Lin, MM1
Clemmey, P1
Brooner, R1
Chutuape, MA1
Kidorf, M1
Schmitz, J1
Day, J1
Wodak, A1
Barnett, PG1
Gibson, CA1
Schmelzle, KH1
Clarke, JG1
McGarry, KA1
Gogineni, A1
Haug, NA1
Stitzer, ML1
Svikis, DS1
Havassy, BE1
Hall, SM1
Wasserman, DA1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Varenicline Smoking Cessation Treatment for Methadone Maintenance Patients[NCT01378858]100 participants (Actual)Interventional2011-07-31Completed
Varenicline Versus Nicotine Replacement for Methadone-Maintained Smokers[NCT00790569]315 participants (Actual)Interventional2008-09-30Completed
Smoking Cessation Treatment for Methadone Maintenance Patients[NCT01027754]Phase 4112 participants (Actual)Interventional2009-08-31Completed
Effectiveness of an Information-Motivation-Behavioral Skills Model-based Intervention on Adherence to Domiciliary Non-invasive Ventilation of Patients With Chronic Hypercapnic Respiratory Failure: A Randomized Controlled Study[NCT05008211]104 participants (Anticipated)Interventional2021-09-16Recruiting
Comprehensive Informatics Framework for Comparative Effectiveness Research (CER) Dissemination[NCT01493258]0 participants (Actual)Interventional2010-08-31Withdrawn (stopped due to PI left JHU and is not able to be reached for updates)
Telemedicine for Smoking Cessation in Rural Primary Care[NCT00843505]Phase 3566 participants (Actual)Interventional2009-06-30Completed
An Innovative Digital Smoking Cessation Intervention for Low-Income Adults With Substance Use Disorder[NCT04419922]100 participants (Actual)Observational2020-04-02Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Tobacco Abstinence Biochemically Verified With Expired Carbon Monoxide (CO) < 8 p.p.m. at 12 Weeks

Number of participants achieving self reported, seven day point prevalence abstinence, biochemically verified with expired carbon monoxide (CO) < 8 p.p.m., missing = smoking (NCT01378858)
Timeframe: Week 12 of treatment

InterventionParticipants (Count of Participants)
Varenicline Treatment as Usual (TAU)9
Varenicline Directly Observed Therapy5

Tobacco Abstinence Biochemically Verified With Expired Carbon Monoxide (CO) < 8 p.p.m. at 24 Weeks

Number of participants achieving self reported, seven day point prevalence abstinence, biochemically verified with expired carbon monoxide (CO) < 8 p.p.m. (NCT01378858)
Timeframe: 24 weeks

InterventionParticipants (Count of Participants)
Varenicline Treatment as Usual (TAU)6
Varenicline Directly Observed Therapy2

Varenicline Adherence as Measured by Pill Count

Pill count adherence, measured as pills taken divided by pills dispensed, analyzed as a continuous measure (NCT01378858)
Timeframe: Weeks 0-1, 1-2, 2-3, 4-6, 7-9, 10-12

Interventionpercentage pills taken/pills dispensed (Mean)
Varenicline Treatment as Usual (TAU)61.8
Varenicline Directly Observed Therapy78.5

Carbon Monoxide (CO)-Confirmed 7-day Abstinence

Number of participants reporting 7-day abstinence at 6-months, confirmed with CO measurement. (NCT00790569)
Timeframe: 6-Months

Interventionparticipants (Number)
Arm I5
Arm II1
Arm III11

Change in Cigarettes Per Day

Change in mean cigarettes per day (NCT00790569)
Timeframe: 6-Months

Interventioncigarettes/day (Mean)
Arm I-8.7
Arm II-8.5
Arm III-7.8

Change in Smoking Urges

Smoking urges was measured on a 0 (not at all) - 100 (strongest feeling possible) scale. Higher values represent greater urge to smoke. Change in smoking urges was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-29.971
Arm II-25.015
Arm III-24.177

CO-confirmed 7-day Abstinence

Number of participants reporting 7-day abstinence at 12-months, confirmed with CO measurement. (NCT00790569)
Timeframe: 12 Months

Interventionparticipants (Number)
Arm I4
Arm II1
Arm III8

Rates of Smoking Cessation Continuous From First Quit Day to 6 Months

Number of participants who self-reported continuous abstinence from their initial quit day (study day 14) to 6 Months (NCT00790569)
Timeframe: 6-Months

Interventionparticipants (Number)
Arm I2
Arm II0
Arm III2

Reinforcing Effects of Smoking

Reinforcing effects of smoking was measured using the modified version of the Cigarette Evaluation Questionnaire. Participants were asked to indicate on a 12-item scale how smoking made them feel in the prior 30 days on a scale from 1 (Not at all) to 7 (Extremely). Higher values indicated that smoking was a more positive experience for 10 of 12 items. Two items were reverse coded. Change in reinforcing effects of smoking was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-1.005
Arm II-.683
Arm III-.761

Self- Reported 7-day Abstinence

Number of participants with self-reported, 7-day abstinence at 6-months (NCT00790569)
Timeframe: 6 Months

Interventionparticipants (Number)
Arm I11
Arm II3
Arm III16

Self-reported 7-day Abstinence

Number of participants with self-reported 7-day abstinence at 12-months (NCT00790569)
Timeframe: 12 Months

Interventionparticipants (Number)
Arm I4
Arm II3
Arm III11

Withdrawal Symptoms

Withdrawal Symptoms were measured using a modified version of the Minnesota Behavior Rating Scale. The scale asked subjects to rate their smoking withdrawal symptoms over the previous 24 hours on a scale from 0 (none) to 4 (severe). Higher values indicate more severe withdrawal symptoms. Change in withdrawal symptoms was calculated as Follow-up score (6 month) - Baseline Score. (NCT00790569)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Arm I-.222
Arm II-.163
Arm III-.113

Biochemically Verified Abstinence Verified With Expired Carbon Monoxide (CO) < 8 p.p.m.

(NCT01027754)
Timeframe: Week 12

Interventionparticipants (Number)
Varenicline6
Placebo0

Biochemically Verified Abstinence Verified With Expired Carbon Monoxide (CO) < 8 p.p.m.

(NCT01027754)
Timeframe: Week 24

Interventionparticipants (Number)
Varenicline3
Placebo0

Number of Counseling Visits Completed

Participants were offered 5 counseling visits at weeks 0, 2, 4, 8, 12. (NCT01027754)
Timeframe: End of 12 week intervention period

Interventionvisits completed (Mean)
Varenicline1.96
Placebo1.85

Number of Study Visits Completed

Mean number of study visit completed out of a possible total of 6 study visits at weeks 0, 2, 4, 8, 12 and 24. (NCT01027754)
Timeframe: 24 weeks

Interventionvisits completed (Mean)
Varenicline5.72
Placebo5.36

Adverse Medication Effects

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Change in tasteDry MouthChange in appetiteNauseaVomitingGasConstipationChange in concentrationHeadacheFatigueInsomniaDizzinessIrritabilityVivid/more frequent dreams
Placebo14231814815961813138822
Varenicline18272929111923611151591018

Confidence in Quitting Smoking (1-10 Scale)

Confidence of quitting smoking measure on a scale of 1-10 (10= high levels of quit confidence). (NCT01027754)
Timeframe: Weeks 2, 4, 8, 12, and 24

,
Interventionunits on a scale (Median)
At week 2At week 4At week 8At week 12At week 24
Placebo88988
Varenicline89998

Importance of Quitting Smoking (1-10 Scale)

Importance of quitting smoking measured on a scale of 1-10 (10=high levels of quit importance). (NCT01027754)
Timeframe: Weeks 2, 4, 8, 12, and 24

,
Interventionunits on a scale (Median)
At week 2At week 4At week 8At week 12At week 24
Placebo1010101010
Varenicline1010101010

Number of Cigarettes Smoked Per Day

(NCT01027754)
Timeframe: Weeks 2, 4, 8, 12, and 24

,
Interventioncigarettes/day (Median)
At week 2At week 4At week 8At week 12At week 24
Placebo65555
Varenicline32324

Number of Participants With an Attempt to Quit Smoking That Lasted ≥ 24 Hours

(NCT01027754)
Timeframe: Weeks 2, 4, 8, 12, and 24

,
Interventionparticipants (Number)
At week 2At week 4At week 8At week 12At week 24
Placebo2527322530
Varenicline3335373741

Number of Participants With Major Depressive Episode, Assessed by the Mini-International Neuropsychiatric Interview

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Week 2Week 4Week 8Week 12Week 24
Placebo00012
Varenicline00202

Number of Participants With Manic Episode, Assessed by the Mini-International Neuropsychiatric Interview

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Week 2Week 4Week 8Week 12Week 24
Placebo00000
Varenicline00000

Number of Participants With Psychotic Disorder, Assessed by the Mini-International Neuropsychiatric Interview

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Week 2Week 4Week 8Week 12Week 24
Placebo20011
Varenicline00112

Number of Participants With Severe Global Psychiatric Symptoms Assessed by the Brief Symptom Inventory

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Week 2Week 4Week 8Week 12Week 24
Placebo117755
Varenicline94685

Number of Patients With Suicial Ideation (Wishes to be Dead, or Thoughts of Killing Self) Assessed Using the Columbia Suicide Severity Scale

(NCT01027754)
Timeframe: over the intervention period (measured at weeks 2, 4, 8, 12, and 24)

,
Interventionparticipants (Number)
Week 2Week 4Week 8Week 12Week 24
Placebo10121
Varenicline11111

Reviews

8 reviews available for methadone and Smoking Cessation

ArticleYear
Smoking Cessation Among Methadone-Maintained Patients: A Meta-Analysis.
    Substance use & misuse, 2018, 01-28, Volume: 53, Issue:2

    Topics: Combined Modality Therapy; Humans; Methadone; Opiate Substitution Treatment; Psychotherapy; Smoking

2018
Cigarette smoking in methadone maintained patients: an up-to-date review.
    Current drug abuse reviews, 2013, Volume: 6, Issue:1

    Topics: Behavior, Addictive; Drug Interactions; Humans; Methadone; Narcotics; Nicotine; Nicotinic Agonists;

2013
Treating tobacco use disorder in pregnant women in medication-assisted treatment for an opioid use disorder: a systematic review.
    Journal of substance abuse treatment, 2015, Volume: 52

    Topics: Analgesics, Opioid; Behavior Therapy; Buprenorphine; Female; Humans; Methadone; Opiate Substitution

2015
Are Pharmacotherapies Ineffective in Opioid-Dependent Smokers? Reflections on the Scientific Literature and Future Directions.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2015, Volume: 17, Issue:8

    Topics: Analgesics, Opioid; Bupropion; Forecasting; Humans; Methadone; Opioid-Related Disorders; Randomized

2015
Methadone's effect on nAChRs--a link between methadone use and smoking?
    Biochemical pharmacology, 2015, Oct-15, Volume: 97, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics, Opioid; Humans; Methadone; Nicotinic Agonists;

2015
Smoking cessation interventions among individuals in methadone maintenance: a brief review.
    Journal of substance abuse treatment, 2010, Volume: 38, Issue:2

    Topics: Female; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Smoking; Smoking Cessation; So

2010
A case for addressing cigarette use in methadone and other opioid treatment programs.
    Journal of addictive diseases, 2000, Volume: 19, Issue:4

    Topics: Humans; Methadone; Narcotics; Opioid-Related Disorders; Prevalence; Psychotherapy, Brief; Regional M

2000
The cost-effectiveness of substance abuse treatment.
    Current psychiatry reports, 1999, Volume: 1, Issue:2

    Topics: Cost-Benefit Analysis; Health Care Costs; Humans; Methadone; Narcotics; Quality-Adjusted Life Years;

1999

Trials

24 trials available for methadone and Smoking Cessation

ArticleYear
Bupropion Slow Release vs Placebo With Adaptive Incentives for Cocaine Use Disorder in Persons Receiving Methadone for Opioid Use Disorder: A Randomized Clinical Trial.
    JAMA network open, 2023, 03-01, Volume: 6, Issue:3

    Topics: Bupropion; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Male; Methadone;

2023
Effect of varenicline directly observed therapy versus varenicline self-administered therapy on varenicline adherence and smoking cessation in methadone-maintained smokers: a randomized controlled trial.
    Addiction (Abingdon, England), 2021, Volume: 116, Issue:4

    Topics: Directly Observed Therapy; Female; Humans; Male; Methadone; Middle Aged; Smokers; Smoking Cessation;

2021
Pilot Study of a Tailored Smoking Cessation Intervention for Individuals in Treatment for Opioid Dependence.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2018, 08-14, Volume: 20, Issue:9

    Topics: Adult; Analgesics, Opioid; Behavior Therapy; Female; Humans; Male; Methadone; Middle Aged; Nicotine;

2018
Varenicline for smoking cessation among methadone-maintained smokers: a randomized clinical trial.
    Drug and alcohol dependence, 2013, Dec-01, Volume: 133, Issue:2

    Topics: Adult; Benzazepines; Carbon Monoxide; Female; Follow-Up Studies; Guideline Adherence; Heroin Depende

2013
Varenicline efficacy and safety among methadone maintained smokers: a randomized placebo-controlled trial.
    Addiction (Abingdon, England), 2014, Volume: 109, Issue:9

    Topics: Benzazepines; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; New York City; Nico

2014
Rationale and design of a randomized controlled trial of varenicline directly observed therapy delivered in methadone clinics.
    Addiction science & clinical practice, 2014, Jun-13, Volume: 9

    Topics: Adult; Benzazepines; Cross-Sectional Studies; Directly Observed Therapy; Female; Follow-Up Studies;

2014
Early quit days among methadone-maintained smokers in a smoking cessation trial.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014, Volume: 16, Issue:11

    Topics: Adult; Benzazepines; Female; Humans; Male; Medication Adherence; Methadone; Middle Aged; Opiate Subs

2014
Barriers to Telephone Quitline Use Among Methadone-Maintained Smokers.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2015, Volume: 17, Issue:8

    Topics: Adult; Cell Phone; Female; Hotlines; Humans; Male; Methadone; Middle Aged; New York; Opiate Substitu

2015
An Open Trial of Electronic Cigarettes for Smoking Cessation Among Methadone-Maintained Smokers.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2016, Volume: 18, Issue:5

    Topics: Adult; Electronic Nicotine Delivery Systems; Female; Humans; Male; Methadone; Middle Aged; Opiate Su

2016
Design considerations for a pilot trial using a novel approach for evaluating smoking-cessation medication in methadone-maintained smokers.
    Contemporary clinical trials, 2016, Volume: 47

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Clinical Protocols; Cross-Over Studi

2016
Voucher-based contingent reinforcement of smoking abstinence among methadone-maintained patients: a pilot study.
    Journal of applied behavior analysis, 2008,Winter, Volume: 41, Issue:4

    Topics: Adult; Cocaine-Related Disorders; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male

2008
Methadone-nicotine interactions in methadone maintenance treatment patients.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:3

    Topics: Adult; Double-Blind Method; Drug Interactions; Female; Humans; Male; Methadone; Middle Aged; Narcoti

2009
Smoking cessation treatment among patients in community-based substance abuse rehabilitation programs: exploring predictors of outcome as clues toward treatment improvement.
    The American journal of drug and alcohol abuse, 2011, Volume: 37, Issue:5

    Topics: Adult; Age Factors; Alcoholism; Community Health Services; Ethnicity; Female; Humans; Male; Methadon

2011
The social support and social network characteristics of smokers in methadone maintenance treatment.
    The American journal of drug and alcohol abuse, 2013, Volume: 39, Issue:1

    Topics: Adult; Female; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Self Efficacy; S

2013
Contingent incentives reduce cigarette smoking among pregnant, methadone-maintained women: results of an initial feasibility and efficacy randomized clinical trial.
    Addiction (Abingdon, England), 2012, Volume: 107, Issue:10

    Topics: Adult; Behavior Therapy; Carbon Monoxide; Feasibility Studies; Female; Humans; Methadone; Motivation

2012
Using latent-variable models to analyze smoking cessation clinical trial data: an example among the methadone maintained.
    Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:3

    Topics: Behavior, Addictive; Clinical Trials as Topic; Heroin Dependence; Humans; Methadone; Models, Statist

2002
Smoking cessation in methadone maintenance.
    Addiction (Abingdon, England), 2002, Volume: 97, Issue:10

    Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Nicotine; Smoking;

2002
Respiratory symptom relief related to reduction in cigarette use.
    Journal of general internal medicine, 2005, Volume: 20, Issue:10

    Topics: Adult; Female; Follow-Up Studies; Humans; Male; Methadone; Respiratory Tract Diseases; Smoking Cessa

2005
Dual pharmacotherapy and motivational interviewing for tobacco dependence among drug treatment patients.
    Journal of addictive diseases, 2005, Volume: 24, Issue:4

    Topics: Administration, Topical; Bupropion; Counseling; Dopamine Uptake Inhibitors; Follow-Up Studies; Human

2005
Dual pharmacotherapy and motivational interviewing for tobacco dependence among drug treatment patients.
    Journal of addictive diseases, 2005, Volume: 24, Issue:4

    Topics: Administration, Topical; Bupropion; Counseling; Dopamine Uptake Inhibitors; Follow-Up Studies; Human

2005
Dual pharmacotherapy and motivational interviewing for tobacco dependence among drug treatment patients.
    Journal of addictive diseases, 2005, Volume: 24, Issue:4

    Topics: Administration, Topical; Bupropion; Counseling; Dopamine Uptake Inhibitors; Follow-Up Studies; Human

2005
Dual pharmacotherapy and motivational interviewing for tobacco dependence among drug treatment patients.
    Journal of addictive diseases, 2005, Volume: 24, Issue:4

    Topics: Administration, Topical; Bupropion; Counseling; Dopamine Uptake Inhibitors; Follow-Up Studies; Human

2005
A smoking cessation intervention for the methadone-maintained.
    Addiction (Abingdon, England), 2006, Volume: 101, Issue:4

    Topics: Adult; Combined Modality Therapy; Female; Humans; Male; Methadone; Middle Aged; Nicotine; Opioid-Rel

2006
Smoking cessation patterns in methadone-maintained smokers.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2007, Volume: 9, Issue:3

    Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Confidence Intervals; Female; Humans; M

2007
Relationship of depression to smoking outcomes in a methadone-maintained population.
    Journal of addictive diseases, 2007, Volume: 26, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Depressive Disorder, Major; Diagnostic and Statistical

2007
Patterns of smoking and methadone dose in drug treatment patients.
    Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:2

    Topics: Adult; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Retros

2007
Effects of nicotine on methadone self-administration in humans.
    Drug and alcohol dependence, 1998, Apr-01, Volume: 50, Issue:2

    Topics: Adult; Analysis of Variance; Behavior, Addictive; Carbon Monoxide; Drug Interactions; Female; Heroin

1998

Other Studies

35 other studies available for methadone and Smoking Cessation

ArticleYear
Pregnant Smokers Receiving Opioid Agonist Therapy Have an Elevated Nicotine Metabolite Ratio: A Replication Study.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2020, 10-08, Volume: 22, Issue:10

    Topics: Analgesics, Opioid; Bupropion; Cotinine; Female; Humans; Methadone; Nicotine; Opiate Substitution Tr

2020
Determining Smoking Cessation Related Information, Motivation, and Behavioral Skills among Opiate Dependent Smokers in Methadone Treatment.
    Substance use & misuse, 2015, Volume: 50, Issue:5

    Topics: Adult; Female; Humans; Male; Methadone; Middle Aged; Models, Psychological; Motivation; Narcotics; O

2015
Motivation for smoking cessation among drug-using smokers under methadone maintenance treatment in Vietnam.
    Harm reduction journal, 2015, Oct-30, Volume: 12

    Topics: Adult; Cross-Sectional Studies; Female; Humans; Male; Methadone; Motivation; Opiate Substitution Tre

2015
Quitting smoking during substance use disorders treatment: Patient and treatment-related variables.
    Journal of substance abuse treatment, 2017, Volume: 73

    Topics: Adult; Ambulatory Care; Analgesics, Opioid; Female; Humans; Male; Methadone; Middle Aged; Opiate Sub

2017
Feasibility of promoting smoking cessation among methadone users using multimedia computer-assisted education.
    Journal of medical Internet research, 2008, Nov-03, Volume: 10, Issue:5

    Topics: Attitude to Health; Computers; Health Knowledge, Attitudes, Practice; Health Promotion; Health Surve

2008
Temporal changes of smoking status and motivation among Chinese heroin-dependent, methadone-maintained smokers.
    Addictive behaviors, 2010, Volume: 35, Issue:10

    Topics: Adult; China; Drug Interactions; Female; Heroin Dependence; Humans; Male; Methadone; Motivation; Nar

2010
Nicotine dependence and depression among women smokers on methadone maintenance.
    The European journal of general practice, 2010, Volume: 16, Issue:4

    Topics: Adult; Cross-Sectional Studies; Depression; Female; Humans; Linear Models; Methadone; Middle Aged; N

2010
Methadone toxicity due to smoking cessation--a case report on the drug-drug interaction involving cytochrome P450 isoenzyme 1A2.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:6

    Topics: Analgesics, Opioid; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drug Interactions; Hu

2011
Smoking cessation among Australian methadone clients: prevalence, characteristics and a need for action.
    Drug and alcohol review, 2012, Volume: 31, Issue:4

    Topics: Adult; Australia; Cross-Sectional Studies; Female; Heroin Dependence; Humans; Male; Methadone; Motiv

2012
The New York policy on smoking in addiction treatment: findings after 1 year.
    American journal of public health, 2012, Volume: 102, Issue:5

    Topics: Adult; Female; Financing, Government; Health Knowledge, Attitudes, Practice; Health Personnel; Healt

2012
Low incidence of adverse events following varenicline initiation among opioid dependent smokers with comorbid psychiatric illness.
    Drug and alcohol dependence, 2013, Sep-01, Volume: 132, Issue:1-2

    Topics: Benzazepines; Cardiovascular Diseases; Comorbidity; Data Interpretation, Statistical; Female; Humans

2013
Optimizing smoking cessation outcomes among the methadone maintained.
    Journal of substance abuse treatment, 2002, Volume: 23, Issue:4

    Topics: Adult; Female; Heroin Dependence; Humans; Los Angeles; Male; Methadone; Middle Aged; Narcotics; Nico

2002
Patients' views on smoking cessation and tobacco harm reduction during drug treatment.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2002, Volume: 4 Suppl 2

    Topics: Adult; Attitude to Health; Female; Harm Reduction; Humans; Male; Methadone; Motivation; Narcotics; S

2002
Why do so many drug users smoke?
    Journal of substance abuse treatment, 2003, Volume: 25, Issue:1

    Topics: Adult; Causality; Comorbidity; Cross-Sectional Studies; Female; Focus Groups; Health Surveys; Heroin

2003
Methadone and nicotine self-administration in humans: a behavioral economic analysis.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Adult; Choice Behavior; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interac

2005
Smoking cessation services in U.S. methadone maintenance facilities.
    Psychiatric services (Washington, D.C.), 2004, Volume: 55, Issue:11

    Topics: Adult; Combined Modality Therapy; Comorbidity; Counseling; Cross-Sectional Studies; Female; Health S

2004
Correlates of motivation to quit smoking in methadone-maintained smokers enrolled in a smoking cessation trial.
    Addictive behaviors, 2005, Volume: 30, Issue:2

    Topics: Adult; Attitude to Health; Cross-Sectional Studies; Female; Humans; Male; Methadone; Motivation; Opi

2005
Assessing missing data assumptions in longitudinal studies: an example using a smoking cessation trial.
    Drug and alcohol dependence, 2005, Mar-07, Volume: 77, Issue:3

    Topics: Bias; Carbon Monoxide; Clinical Trials as Topic; Computer Graphics; Data Collection; Data Interpreta

2005
Perceptions of health risk susceptibility in methadone maintained smokers.
    Journal of addictive diseases, 2005, Volume: 24, Issue:1

    Topics: Adult; Attitude to Health; Female; Health Status; Humans; Lung Neoplasms; Male; Methadone; Middle Ag

2005
Addressing smoking cessation in methadone programs.
    Journal of addictive diseases, 2005, Volume: 24, Issue:2

    Topics: Adult; Demography; Female; Humans; Male; Methadone; Narcotics; Smoking Cessation; Smoking Prevention

2005
Self-reported effects of methadone on cigarette smoking in methadone-maintained subjects.
    Substance use & misuse, 2005, Volume: 40, Issue:8

    Topics: Adult; Female; Humans; Male; Methadone; Poland; Self Disclosure; Smoking; Smoking Cessation; Surveys

2005
Longitudinal predictors of injection cessation and subsequent relapse among a cohort of injection drug users in Baltimore, MD, 1988-2000.
    Drug and alcohol dependence, 2006, Jun-28, Volume: 83, Issue:2

    Topics: Adult; Baltimore; Cohort Studies; Female; HIV Infections; Humans; Ill-Housed Persons; Incidence; Lon

2006
Cigarette smoking and interest in quitting in methadone maintenance patients.
    Addictive behaviors, 2006, Volume: 31, Issue:11

    Topics: Adult; Aged; Cross-Sectional Studies; Drug Administration Schedule; Female; Health Care Surveys; Hum

2006
[Bupropion in cigarettes smoking cessation by former polydrug user participating in methadone maintenance programme].
    Przeglad lekarski, 2005, Volume: 62, Issue:10

    Topics: Bupropion; Dopamine Uptake Inhibitors; Electroencephalography; Heroin Dependence; Humans; Male; Meth

2005
Nicotine replacement therapy: patterns of use after a quit attempt among methadone-maintained smokers.
    Journal of general internal medicine, 2006, Volume: 21, Issue:7

    Topics: Administration, Topical; Adult; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Nic

2006
Good and bad times for treating cigarette smoking in drug treatment.
    Journal of psychoactive drugs, 2006, Volume: 38, Issue:3

    Topics: Analgesics, Opioid; Attitude of Health Personnel; Data Collection; Humans; Methadone; Smoking Cessat

2006
Drug use and cigarette smoking in applicants for drug abuse treatment.
    Journal of substance abuse, 1993, Volume: 5, Issue:2

    Topics: Adult; Alcoholism; Comorbidity; Female; Heroin Dependence; Humans; Male; Methadone; Oregon; Smoking;

1993
Nicotine dependence and depression among methadone maintenance patients.
    Journal of the National Medical Association, 1996, Volume: 88, Issue:12

    Topics: Adult; Aged; Depression; Female; Humans; Logistic Models; Male; Methadone; Middle Aged; Nicotine; Od

1996
Smoking habits and attitudes in a methadone maintenance treatment population.
    Drug and alcohol dependence, 1997, Mar-14, Volume: 44, Issue:2-3

    Topics: Adult; Ambulatory Care; Attitude to Health; Cohort Studies; Comorbidity; Female; Heroin Dependence;

1997
Interest in smoking cessation among methadone maintained outpatients.
    Journal of addictive diseases, 1998, Volume: 17, Issue:2

    Topics: Adult; Ambulatory Care; Analgesics, Opioid; Female; Humans; Male; Marijuana Abuse; Methadone; Motiva

1998
Harm reduction: Australia as a case study.
    Bulletin of the New York Academy of Medicine, 1995,Winter, Volume: 72, Issue:2

    Topics: Alcoholism; Australia; Health Policy; HIV Infections; Humans; Illicit Drugs; Methadone; Needle-Excha

1995
Tobacco use and quit attempts among methadone maintenance clients.
    American journal of public health, 2001, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Attitude to Health; Female; Health K

2001
Interest in smoking cessation among injection drug users.
    The American journal on addictions, 2001,Spring, Volume: 10, Issue:2

    Topics: Adult; Female; Humans; Male; Methadone; Motivation; Narcotic Antagonists; Smoking Cessation; Substan

2001
Smoking during pregnancy and intention to quit: a profile of methadone-maintained women.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2001, Volume: 3, Issue:4

    Topics: Adult; Attitude to Health; Carbon Monoxide; Cotinine; Ethnicity; Female; Follow-Up Studies; Heroin D

2001
Social support and relapse: commonalities among alcoholics, opiate users, and cigarette smokers.
    Addictive behaviors, 1991, Volume: 16, Issue:5

    Topics: Adult; Alcoholism; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Opioid-Related D

1991