methadone has been researched along with Sleep Apnea, Obstructive in 3 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objectives were to: (1) characterize obstructive sleep apnea (OSA) and CSA in patients in methadone maintenance treatment (MMT) for opioid dependence; (2) examine factors associated with SDB in this population; and (3) investigate whether SDB was related to severity of subjective sleep complaints in MMT patients with subjective sleep disturbances." | 1.36 | Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints. ( Anderson, BJ; Corso, RP; Kurth, ME; Millman, RP; Sharkey, KM; Stein, MD, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharkey, KM | 1 |
| Kurth, ME | 1 |
| Anderson, BJ | 1 |
| Corso, RP | 1 |
| Millman, RP | 1 |
| Stein, MD | 1 |
| Vecchierini, MF | 1 |
| Laaban, JP | 1 |
| Desjobert, M | 1 |
| Gagnadoux, F | 1 |
| Chabolle, F | 1 |
| Meurice, JC | 1 |
| Sapène, M | 1 |
| Serrier, P | 1 |
| Lévy, P | 1 |
| Dimsdale, JE | 1 |
| Norman, D | 1 |
| DeJardin, D | 1 |
| Wallace, MS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Behavioral Intervention to Improve Insomnia Symptoms in Patients With Opioid Use Disorder[NCT05588726] | 0 participants (Actual) | Interventional | 2022-01-01 | Withdrawn (stopped due to Staff no longer available to continue enrollment and other research activities) | |||
| The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methadone and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
The effect of opioids on sleep architecture.
Topics: Adolescent; Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Admini | 2007 |
The effect of opioids on sleep architecture.
Topics: Adolescent; Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Admini | 2007 |
The effect of opioids on sleep architecture.
Topics: Adolescent; Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Admini | 2007 |
The effect of opioids on sleep architecture.
Topics: Adolescent; Adult; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Admini | 2007 |
2 other studies available for methadone and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Obstructive sleep apnea is more common than central sleep apnea in methadone maintenance patients with subjective sleep complaints.
Topics: Adult; Body Mass Index; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Diso | 2010 |
[Therapeutic strategies of obstructive sleep apnea syndrome integrating combined treatments?].
Topics: Alcohol Drinking; Benzodiazepines; Combined Modality Therapy; Continuous Positive Airway Pressure; E | 2010 |