methadone has been researched along with Sex Disorders in 24 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypogonadism was found in 68 % of the participants, and about 68." | 5.38 | Depression, Testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV Infection. ( Amini Lari, M; Faramarzi, H; Marzban, M; Parsa, N; Shams, M, 2012) |
| " Methadone is a medication-assisted treatment used to treat opioid dependence and chronic pain." | 5.05 | The effect of methadone on the hypothalamic pituitary gonadal axis and sexual function: A systematic review. ( Ortman, HA; Siegel, JA, 2020) |
| "Bupropion is a dopamine reuptake inhibitor which can potentially improve erectile function among male patients on methadone (MMT)." | 2.87 | Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial of Bupropion as Treatment for Methadone-Emergent Sexual Dysfunction in Men. ( Loh, HS; Ng, CG; Ong, TA; Sulaiman, AH; Yee, A, 2018) |
| "Methadone has been recognized as an effective maintenance treatment for opioid dependence." | 1.48 | Plasma Testosterone and Sexual Function in Southeast Asian Men Receiving Methadone and Buprenorphine Maintenance Treatment. ( Danaee, M; Loh, HS; Ng, CG; Riahi, S; Sulaiman, AH; Yee, A, 2018) |
| "Methadone dosages were recorded among heroin-dependent patients on maintenance treatment." | 1.43 | Sexual Dysfunction in Men Receiving Methadone Maintenance Treatment: Clinical History and Psychobiological Correlates. ( Donnini, C; Gerra, G; Leonardi, C; Manfredini, M; Maremmani, I; Somaini, L, 2016) |
| " We wanted to explore if the Opiate Dosage Adequacy Scale (ODAS) is a helpful instrument in methadone titration." | 1.43 | The opiate dosage adequacy scale for identification of the right methadone dose--a prospective cohort study. ( Koc, J; Reichel, V; Reimer, J; Schlote, F; Verthein, U; Walcher, S, 2016) |
| "Methadone maintenance treatment (MMT) has become an important modality of substitution treatment for opioid addicts in China since 2006." | 1.39 | Sexual dysfunction during methadone maintenance treatment and its influence on patient's life and treatment: a qualitative study in South China. ( Chen, J; Chen, W; He, Q; Hu, P; Jahn, HJ; Li, X; Ling, L; Xia, Y; Zhang, D, 2013) |
| "Hypogonadism was found in 68 % of the participants, and about 68." | 1.38 | Depression, Testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV Infection. ( Amini Lari, M; Faramarzi, H; Marzban, M; Parsa, N; Shams, M, 2012) |
| " Drug intervention should be on a regular schedule--avoid prn dosage of pain medications." | 1.27 | Dilemmas in managing prostate carcinoma (Part II): Metastatic disease. ( Ahmann, FR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (37.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 12 (50.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Ortman, HA | 1 |
| Siegel, JA | 1 |
| Farnia, V | 2 |
| Tatari, F | 1 |
| Alikhani, M | 2 |
| Yazdchi, K | 1 |
| Taghizadeh, M | 1 |
| Sadeghi Bahmani, D | 2 |
| Karbasizadeh, H | 1 |
| Holsboer-Trachsler, E | 1 |
| Brand, S | 2 |
| Yee, A | 3 |
| Loh, HS | 3 |
| Danaee, M | 1 |
| Riahi, S | 1 |
| Ng, CG | 3 |
| Sulaiman, AH | 2 |
| Ong, TA | 1 |
| Ebrahimi, A | 1 |
| Golshani, S | 1 |
| Trajanovska, AS | 1 |
| Vujovic, V | 1 |
| Ignjatova, L | 1 |
| Janicevic-Ivanovska, D | 1 |
| Cibisev, A | 1 |
| Hisham Hashim, HM | 1 |
| Zhang, M | 2 |
| Zhang, H | 1 |
| Shi, CX | 1 |
| McGoogan, JM | 1 |
| Zhang, B | 1 |
| Zhao, L | 1 |
| Rou, K | 1 |
| Wu, Z | 1 |
| Gerra, G | 1 |
| Manfredini, M | 1 |
| Somaini, L | 1 |
| Maremmani, I | 1 |
| Leonardi, C | 1 |
| Donnini, C | 1 |
| Walcher, S | 1 |
| Koc, J | 1 |
| Reichel, V | 1 |
| Schlote, F | 1 |
| Verthein, U | 1 |
| Reimer, J | 1 |
| Chekuri, V | 1 |
| Gerber, D | 1 |
| Brodie, A | 1 |
| Krishnadas, R | 1 |
| Amini Lari, M | 1 |
| Parsa, N | 1 |
| Marzban, M | 1 |
| Shams, M | 1 |
| Faramarzi, H | 1 |
| Xia, Y | 1 |
| Zhang, D | 1 |
| Li, X | 2 |
| Chen, W | 1 |
| He, Q | 1 |
| Jahn, HJ | 1 |
| Chen, J | 1 |
| Hu, P | 1 |
| Ling, L | 1 |
| Brown, R | 1 |
| Balousek, S | 1 |
| Mundt, M | 1 |
| Fleming, M | 1 |
| Lafisca, S | 1 |
| Bolelli, G | 1 |
| Franceschetti, F | 1 |
| Filicori, M | 1 |
| Flamigni, C | 1 |
| Marigo, M | 1 |
| Langrod, J | 1 |
| Lowinson, J | 1 |
| Ruiz, P | 1 |
| Hanbury, R | 1 |
| Cohen, M | 1 |
| Stimmel, B | 1 |
| Spring, WD | 1 |
| Willenbring, ML | 2 |
| Maddux, TL | 1 |
| Morley, JE | 1 |
| Krahn, DD | 1 |
| Carlson, GA | 1 |
| Levine, AS | 1 |
| Shafer, RB | 1 |
| Ahmann, FR | 1 |
| Sutker, PB | 1 |
| Allain, AN | 1 |
| Mintz, J | 1 |
| O'Hare, K | 1 |
| O'Brien, CP | 1 |
| Goldschmidt, J | 1 |
| Yaffe, GJ | 1 |
| Strelinger, RW | 1 |
| Parwatikar, S | 1 |
| Gossop, MR | 1 |
| Stern, R | 1 |
| Connell, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-treated Chronic Pain Patients: A Pilot Study.[NCT00398034] | Phase 2 | 0 participants (Actual) | Interventional | 2006-10-30 | Withdrawn (stopped due to The original PI (David Siegel) Left the VA) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methadone and Sex Disorders
| Article | Year |
|---|---|
The effect of methadone on the hypothalamic pituitary gonadal axis and sexual function: A systematic review.
Topics: Analgesics, Opioid; Animals; Chronic Pain; Female; Gonadal Disorders; Humans; Hypothalamo-Hypophysea | 2020 |
The prevalence of sexual dysfunction among male patients on methadone and buprenorphine treatments: a meta-analysis study.
Topics: Buprenorphine; Humans; Male; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Pre | 2014 |
3 trials available for methadone and Sex Disorders
| Article | Year |
|---|---|
Rosa Damascena oil improved methadone-related sexual dysfunction in females with opioid use disorder under methadone maintenance therapy - results from a double-blind, randomized, and placebo-controlled trial.
Topics: Adult; Analgesics, Opioid; Double-Blind Method; Female; Gonadal Steroid Hormones; Happiness; Humans; | 2017 |
Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial of Bupropion as Treatment for Methadone-Emergent Sexual Dysfunction in Men.
Topics: Adult; Bupropion; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedul | 2018 |
Ginseng treatment improves the sexual side effects of methadone maintenance treatment.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatm | 2019 |
19 other studies available for methadone and Sex Disorders
| Article | Year |
|---|---|
Plasma Testosterone and Sexual Function in Southeast Asian Men Receiving Methadone and Buprenorphine Maintenance Treatment.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Depression; Female; Humans; Hypogonadism; Male; Methadone; | 2018 |
Sexual dysfunction as a side effect of hyperprolactinemia in methadone maintenance therapy.
Topics: Heroin Dependence; Humans; Hyperprolactinemia; Male; Methadone; Narcotics; Opiate Substitution Treat | 2013 |
Sexual dysfunction improved in heroin-dependent men after methadone maintenance treatment in Tianjin, China.
Topics: Adult; China; Demography; Depression; Heroin Dependence; Humans; Maintenance Chemotherapy; Male; Met | 2014 |
Sexual Dysfunction in Men Receiving Methadone Maintenance Treatment: Clinical History and Psychobiological Correlates.
Topics: Adult; Adult Survivors of Child Abuse; Case-Control Studies; Comorbidity; Diagnosis, Dual (Psychiatr | 2016 |
The opiate dosage adequacy scale for identification of the right methadone dose--a prospective cohort study.
Topics: Adult; Ambulatory Care Facilities; Analgesics, Opioid; Cohort Studies; Drug Monitoring; Female; Germ | 2016 |
Premature ejaculation and other sexual dysfunctions in opiate dependent men receiving methadone substitution treatment.
Topics: Adult; Cross-Sectional Studies; Ejaculation; Heroin; Humans; Interviews as Topic; Male; Methadone; M | 2012 |
Depression, Testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV Infection.
Topics: Adult; Cross-Sectional Studies; Depression; Female; HIV Infections; Humans; Hypogonadism; Iran; Logi | 2012 |
Sexual dysfunction during methadone maintenance treatment and its influence on patient's life and treatment: a qualitative study in South China.
Topics: Adaptation, Psychological; Adult; Analgesics, Opioid; China; Female; Heroin Dependence; Humans; Inte | 2013 |
Methadone maintenance and male sexual dysfunction.
Topics: Adult; Demography; Erectile Dysfunction; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Rel | 2005 |
Hormone levels in methadone-treated drug addicts.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradio | 1981 |
Methadone treatment and physical complaints: a clinical analysis.
Topics: Bone Diseases; Constipation; Female; Humans; Male; Methadone; Sexual Dysfunction, Physiological; Sle | 1981 |
Adequacy of sexual performance in men maintained on methadone.
Topics: Adult; Ejaculation; Erectile Dysfunction; Female; Humans; Libido; Male; Methadone; Sexual Dysfunctio | 1977 |
Sexual dysfunction and psychological distress in methadone maintenance.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Female; Humans; Hyperprolactinemia; Male; Methadone; | 1992 |
Psychoneuroendocrine effects of methadone maintenance.
Topics: Adrenocorticotropic Hormone; Adult; Energy Intake; Growth Hormone; Humans; Hydrocortisone; Insulin; | 1989 |
Dilemmas in managing prostate carcinoma (Part II): Metastatic disease.
Topics: Aged; Aminoglutethimide; Aspirin; Bone Neoplasms; Castration; Diethylstilbestrol; Disseminated Intra | 1985 |
Addict attitudes toward methadone maintenance: a preliminary report.
Topics: Adult; Attitude to Health; Criminal Psychology; Educational Status; Female; Heroin Dependence; Human | 1974 |
Sexual problems of heroin addicts.
Topics: Adult; Age Factors; Black or African American; Educational Status; Ejaculation; Erectile Dysfunction | 1974 |
Physical symptom complaints of patients on methadone maintenance.
Topics: Constipation; Dose-Response Relationship, Drug; Female; Heroin Dependence; Humans; Male; Methadone; | 1973 |
Drug dependence and sexual dysfunction: a comparison of intravenous users of narcotics and oral users of amphetamines.
Topics: Administration, Oral; Amenorrhea; Amphetamine; Barbiturates; Female; Humans; Injections, Intravenous | 1974 |