Page last updated: 2024-10-30

methadone and Rhabdomyolysis

methadone has been researched along with Rhabdomyolysis in 12 studies

Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
" We present a case of a 23-year-old man who had acute necrosis of the bilateral globi pallidi in the brain and systemic rhabdomyolysis after ingesting methadone and nasally insufflating alprazolam."7.79Bilateral acute necrosis of the globi pallidi and rhabdomyolysis due to combined methadone and benzodiazepine toxicity. ( Corliss, RF; Mandal, R; Soriano, BJ, 2013)
"Those using methadone and heroin simultaneously may increase risk of rhabdomyolysis and ischemic stroke."7.75Rhabdomyolysis and brain ischemic stroke in a heroin-dependent male under methadone maintenance therapy. ( Chiu, NY; Hsu, WY; Liao, YC, 2009)
"Our patient simultaneously had kidney failure, rhabdomyolysis, and permanent hearing loss following methadone poisoning."3.91Methadone associated long term hearing loss and nephrotoxicity; a case report and literature review. ( Brent, J; Ghasemi, S; Izadpanahi, S; Mehrpour, O; Yaghoubi, MA, 2019)
" We present a case of a 23-year-old man who had acute necrosis of the bilateral globi pallidi in the brain and systemic rhabdomyolysis after ingesting methadone and nasally insufflating alprazolam."3.79Bilateral acute necrosis of the globi pallidi and rhabdomyolysis due to combined methadone and benzodiazepine toxicity. ( Corliss, RF; Mandal, R; Soriano, BJ, 2013)
"We report a case of IA injection of methadone into the femoral artery causing limb ischemia and rhabdomyolysis."3.76Intra-arterial self-injection of methadone tablets into the femoral artery. ( Gramenz, P; Roberts, D; Schrag, L, 2010)
"Those using methadone and heroin simultaneously may increase risk of rhabdomyolysis and ischemic stroke."3.75Rhabdomyolysis and brain ischemic stroke in a heroin-dependent male under methadone maintenance therapy. ( Chiu, NY; Hsu, WY; Liao, YC, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghasemi, S1
Izadpanahi, S1
Yaghoubi, MA1
Brent, J1
Mehrpour, O1
Gramenz, P1
Roberts, D1
Schrag, L1
Hsu, WY1
Chiu, NY1
Liao, YC1
Somala, RK1
Valga-Amado, F1
Monzón-Vázquez, TR1
Hadad, F1
Torrente-Sierra, J1
Pérez-Flores, I1
Barrientos-Guzmán, A1
Corliss, RF1
Mandal, R1
Soriano, BJ1
Schouwenberg, BJ1
Deinum, J1
Nanji, AA1
Filipenko, JD1
Froomes, PR1
Haddad, J1
Harding, D1
Hojs, R1
Sinkovic, A1
Weston, MD1
Hirsch, NP1
Jones, JA1
Blain, PG1
Lane, RJ1
Bateman, DN1
Rawlins, MD1

Other Studies

12 other studies available for methadone and Rhabdomyolysis

ArticleYear
Methadone associated long term hearing loss and nephrotoxicity; a case report and literature review.
    Substance abuse treatment, prevention, and policy, 2019, 11-06, Volume: 14, Issue:1

    Topics: Adult; Analgesics, Opioid; Hearing Loss, Sensorineural; Humans; Male; Methadone; Renal Insufficiency

2019
Intra-arterial self-injection of methadone tablets into the femoral artery.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Adult; Femoral Artery; Humans; Injections, Intra-Arterial; Ischemia; Male; Methadone; Narcotics; Rha

2010
Rhabdomyolysis and brain ischemic stroke in a heroin-dependent male under methadone maintenance therapy.
    Acta psychiatrica Scandinavica, 2009, Volume: 120, Issue:1

    Topics: Adult; Brain; Brain Damage, Chronic; Cerebral Cortex; Cerebral Hemorrhage; Cerebral Infarction; Domi

2009
Rhabdomyolysis and brain ischemic stroke in a heroin-dependent male. Invited comment.
    Acta psychiatrica Scandinavica, 2009, Volume: 120, Issue:1

    Topics: Adult; Cerebral Cortex; Cerebral Infarction; Drug Synergism; Globus Pallidus; Heroin; Heroin Depende

2009
Rhabdomyolysis with acute renal failure secondary to taking methadone.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2012, Volume: 32, Issue:2

    Topics: Acute Kidney Injury; Adult; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Rhabdomyol

2012
Bilateral acute necrosis of the globi pallidi and rhabdomyolysis due to combined methadone and benzodiazepine toxicity.
    The American journal of forensic medicine and pathology, 2013, Volume: 34, Issue:1

    Topics: Administration, Intranasal; Adult; Alprazolam; Brain; Forensic Pathology; Forensic Toxicology; Glasg

2013
Photo quiz. Oblivion at the kitchen table. Rhabdomyolysis due to drug abuse.
    The Netherlands journal of medicine, 2003, Volume: 61, Issue:5

    Topics: Adult; Humans; Male; Methadone; Narcotics; Rhabdomyolysis; Substance-Related Disorders

2003
Rhabdomyolysis and acute myoglobinuric renal failure associated with methadone intoxication.
    Journal of toxicology. Clinical toxicology, 1983, Volume: 20, Issue:4

    Topics: Acute Kidney Injury; Adult; Animals; Creatinine; Humans; Methadone; Naloxone; Rhabdomyolysis

1983
Coma, myalagia and hypoxia.
    Postgraduate medical journal, 1996, Volume: 72, Issue:852

    Topics: Adult; Coma; Humans; Male; Methadone; Respiratory Insufficiency; Rhabdomyolysis

1996
Rhabdomyolysis and acute renal failure following methadone abuse.
    Nephron, 1992, Volume: 62, Issue:3

    Topics: Acute Kidney Injury; Adult; Humans; Male; Methadone; Rhabdomyolysis; Substance-Related Disorders

1992
Narcotic overdose and acute rhabdomyolysis.
    Anaesthesia, 1986, Volume: 41, Issue:12

    Topics: Acute Disease; Adult; Humans; Male; Methadone; Rhabdomyolysis

1986
Opiate-induced rhabdomyolysis.
    Human toxicology, 1985, Volume: 4, Issue:1

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Codeine; Creatine Kinase; Creatinine; Cycli

1985