methadone has been researched along with Restless Leg Syndrome in 7 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most cases of restless legs syndrome (RLS) initially respond well to dopaminergic agonists." | 5.33 | Methadone for refractory restless legs syndrome. ( Ondo, WG, 2005) |
| "It has been well established that restless legs syndrome (RLS) manifests with symptoms most frequently in the legs followed by the arms." | 1.35 | Restless legs syndrome (RLS) with expansion of symptoms to the face. ( Buchfuhrer, MJ, 2008) |
| "Most cases of restless legs syndrome (RLS) initially respond well to dopaminergic agonists." | 1.33 | Methadone for refractory restless legs syndrome. ( Ondo, WG, 2005) |
| "Three patients with restless legs syndrome, two of whom also had nocturnal myoclonus, responded well to treatment with low doses of opioids." | 1.27 | Response to opioids in three patients with restless legs syndrome. ( Sateia, MJ; Trzepacz, PT; Violette, EJ, 1984) |
| "The restless legs syndrome is a sensory and motor disorder of evening, repose, and sleep." | 1.27 | Dominantly inherited restless legs with myoclonus and periodic movements of sleep: a syndrome related to the endogenous opiates? ( Côté, L; Fahn, S; Hening, W; Walters, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wijemanne, S | 1 |
| Jankovic, J | 1 |
| Silver, N | 1 |
| Allen, RP | 1 |
| Senerth, J | 1 |
| Earley, CJ | 1 |
| Freye, E | 1 |
| Levy, JV | 1 |
| Partecke, L | 1 |
| Ondo, WG | 1 |
| Buchfuhrer, MJ | 1 |
| Trzepacz, PT | 1 |
| Violette, EJ | 1 |
| Sateia, MJ | 1 |
| Walters, A | 1 |
| Hening, W | 1 |
| Côté, L | 1 |
| Fahn, S | 1 |
1 review available for methadone and Restless Leg Syndrome
| Article | Year |
|---|---|
Restless legs syndrome: clinical presentation diagnosis and treatment.
Topics: Amines; Analgesics, Opioid; Benzothiazoles; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapent | 2015 |
1 trial available for methadone and Restless Leg Syndrome
| Article | Year |
|---|---|
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric | 2004 |
5 other studies available for methadone and Restless Leg Syndrome
| Article | Year |
|---|---|
A 10-year, longitudinal assessment of dopamine agonists and methadone in the treatment of restless legs syndrome.
Topics: Analgesics, Opioid; Benzothiazoles; Chronic Disease; Dopamine Agonists; Follow-Up Studies; Humans; K | 2011 |
Methadone for refractory restless legs syndrome.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Administration Schedule; Female; Humans; Ma | 2005 |
Restless legs syndrome (RLS) with expansion of symptoms to the face.
Topics: Adult; Aged; Botulinum Toxins, Type A; Drug Therapy, Combination; Face; Facial Muscles; Female; Huma | 2008 |
Response to opioids in three patients with restless legs syndrome.
Topics: Codeine; Female; Humans; Male; Methadone; Middle Aged; Myoclonus; Oxycodone; Receptors, Opioid; Rest | 1984 |
Dominantly inherited restless legs with myoclonus and periodic movements of sleep: a syndrome related to the endogenous opiates?
Topics: Aged; Dextropropoxyphene; Electrocardiography; Electroencephalography; Electrooculography; Endorphin | 1986 |