methadone has been researched along with Respiration Disorders in 10 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone is a synthetic opioid with excellent oral bioavailability, variable, but long duration of action and extremely low cost." | 5.29 | Respiratory depression in a patient receiving oral methadone for cancer pain. ( Bruera, E; Hunt, G, 1995) |
| " Apnea density and episodes of periodic breathing exceeded the 95th percentile for normal infants in 12 (38%) of 32 of cocaine-exposed infants vs only 1 (6%) of 18 opiate-exposed infants." | 3.67 | Prenatal cocaine exposure is associated with respiratory pattern abnormalities. ( Chasnoff, IJ; Hunt, CE; Kaplan, D; Kletter, R, 1989) |
| "Data analysis from observatory for pharmacodependency in ambulatory medicine survey (observation des pharmacodépendances en médecine ambulatoire [OPEMA]) program in 2013 of the subjects under high dosage buprenorphine (HDB) and methadone prescribed or obtained illegally reported by GPs in France." | 1.43 | [Characteristics of subjects under opiate maintenance treatment in primary care using the OPEMA data 2013]. ( Amaslidou, D; Frauger, E; Gentile, G; Giocanti, A; Micallef, J; Orleans, V; Pauly, V; Thirion, X, 2016) |
| "Methadone is a synthetic opioid with excellent oral bioavailability, variable, but long duration of action and extremely low cost." | 1.29 | Respiratory depression in a patient receiving oral methadone for cancer pain. ( Bruera, E; Hunt, G, 1995) |
| "A sudden and potentially lethal toxic reaction to a previously well-tolerated maintenance dose of methadone occurred in 4 of 6 monkeys." | 1.26 | Sudden toxicity of methadone in monkeys: behavioral and electrophysiological evidence. ( Beck, EC; Dustman, RE; Snyder, EW; Straight, RC; Wayne, AW, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Komatsu, R | 1 |
| Nash, MG | 1 |
| Wu, J | 1 |
| Dinges, EM | 1 |
| Delgado, CM | 1 |
| Bollag, LA | 1 |
| Aghabiklooei, A | 2 |
| Hassanian-Moghaddam, H | 2 |
| Zamani, N | 2 |
| Shadnia, S | 1 |
| Mashayekhian, M | 1 |
| Rahimi, M | 1 |
| Nasouhi, S | 1 |
| Ghoochani, A | 1 |
| Kessler, BD | 1 |
| Hoffman, RS | 1 |
| Gentile, G | 1 |
| Frauger, E | 1 |
| Giocanti, A | 1 |
| Pauly, V | 1 |
| Orleans, V | 1 |
| Amaslidou, D | 1 |
| Thirion, X | 1 |
| Micallef, J | 1 |
| Kreek, MJ | 1 |
| Hartman, N | 1 |
| Hunt, G | 1 |
| Bruera, E | 2 |
| Oneschuk, D | 1 |
| Snyder, EW | 1 |
| Dustman, RE | 1 |
| Straight, RC | 1 |
| Wayne, AW | 1 |
| Beck, EC | 1 |
| Chasnoff, IJ | 1 |
| Hunt, CE | 1 |
| Kletter, R | 1 |
| Kaplan, D | 1 |
1 trial available for methadone and Respiration Disorders
| Article | Year |
|---|---|
Effectiveness of naltrexone in the prevention of delayed respiratory arrest in opioid-naive methadone-intoxicated patients.
Topics: Adolescent; Adult; Analgesics, Opioid; Double-Blind Method; Female; Humans; Iran; Male; Methadone; N | 2013 |
9 other studies available for methadone and Respiration Disorders
| Article | Year |
|---|---|
Prediction of postoperative respiratory depression and respiratory complications in patients on preoperative methadone.
Topics: Humans; Methadone; Postoperative Complications; Respiration Disorders; Respiratory Insufficiency; Re | 2023 |
Comment on "Effectiveness of naltrexone in the prevention of delayed respiratory arrest in opioid-naive methadone-intoxicated patients".
Topics: Analgesics, Opioid; Female; Humans; Male; Methadone; Naltrexone; Respiration Disorders | 2014 |
Comment on "Effectiveness of naltrexone in the prevention of delayed respiratory arrest in opioid-naive methadone-intoxicated patients".
Topics: Analgesics, Opioid; Female; Humans; Male; Methadone; Naltrexone; Respiration Disorders | 2015 |
[Characteristics of subjects under opiate maintenance treatment in primary care using the OPEMA data 2013].
Topics: Adolescent; Adult; Alcohol Drinking; Anxiety; Benzodiazepines; Buprenorphine; Depressive Disorder; D | 2016 |
Chronic use of opioids and antipsychotic drugs: side effects, effects on endogenous opioids, and toxicity.
Topics: Adolescent; Adult; Animals; Antipsychotic Agents; Blood Proteins; Endorphins; Female; Humans; Liver | 1982 |
Respiratory depression in a patient receiving oral methadone for cancer pain.
Topics: Administration, Oral; Female; Humans; Methadone; Middle Aged; Neoplasms; Pain; Respiration Disorders | 1995 |
Respiratory depression during methadone rotation in a patient with advanced cancer.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Humans; Lung Neoplasms; Male; Methadone; Neoplasms; Pai | 2000 |
Sudden toxicity of methadone in monkeys: behavioral and electrophysiological evidence.
Topics: Animals; Behavior, Animal; Electroencephalography; Evoked Potentials; Haplorhini; Macaca; Methadone; | 1977 |
Prenatal cocaine exposure is associated with respiratory pattern abnormalities.
Topics: Apnea; Cheyne-Stokes Respiration; Cocaine; Female; Humans; Infant, Newborn; Methadone; Pregnancy; Pr | 1989 |