methadone has been researched along with Recrudescence in 170 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations." | 8.02 | A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children. ( Farnaghi, F; Gholami, N; Hassanian-Moghaddam, H; McDonald, R; Saberi, M; Zamani, N, 2021) |
| " The group on methadone had a strong depression in all three measurements." | 7.78 | [Differences in depression severity and frequency of relapses in opiate addicts treated with methadone or opiate blocker after detoxification]. ( Jovanović, T; Lazarević, D; Nikolić, G, 2012) |
| "We describe a patient on methadone maintenance who developed distal leg edema after years of treatment." | 7.68 | Methadone and edema. ( Dhopesh, V; Manny, I; O'Conor, LM; Woody, G; Yeh, HS, 1991) |
| "Undertreatment of acute pain is suboptimal medical treatment, and patients receiving long-term OAT are at particular risk." | 6.43 | Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. ( Alford, DP; Compton, P; Samet, JH, 2006) |
| "Thirty-four drug addicts, aged 20 - 24 years, with a history of 4 - 8 years of intravenous heroin abuse, were randomly assigned either to a methadone maintenance treatment (MMT) (17) or to an untreated group (17)." | 5.05 | The Swedish methadone maintenance program: a controlled study. ( Grönbladh, L; Gunne, LM, 1981) |
| " In the United States there are medications available to treat tobacco use disorders (nicotine replacement, bupropion, and varenicline), alcohol use disorders (naltrexone and acamprosate), and opioid use disorders (methadone and buprenorphine)." | 4.93 | Pharmacotherapy for Substance Use Disorders. ( Klein, JW, 2016) |
| " Methadone maintenance therapy is an accepted form of treatment for chronic opiate (eg, heroin) addiction and, not surprisingly, a significant proportion of methadone-treated patients have chronic hepatitis C." | 4.86 | Methadone maintenance therapy in liver transplantation. ( Greanya, ED; Haque, M; Jiao, M; Soos, JG; Yoshida, EM, 2010) |
| "Based on hubs of neural circuits associated with addiction and their degree centrality (DC), this study aimed to construct the addiction-related brain networks for patients diagnosed with heroin dependence undertaking stable methadone maintenance treatment (MMT) and further prospectively identify the ones at high risk for relapse with cluster analysis." | 4.31 | Relapse risk revealed by degree centrality and cluster analysis in heroin addicts undergoing methadone maintenance treatment. ( Guo, J; Hu, F; Li, Q; Li, W; Li, Y; Qin, Y; Shi, H; Wang, L; Wang, W; Wang, Y; Wei, X; Yang, J; Zhu, J, 2023) |
| "The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations." | 4.02 | A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children. ( Farnaghi, F; Gholami, N; Hassanian-Moghaddam, H; McDonald, R; Saberi, M; Zamani, N, 2021) |
| " The group on methadone had a strong depression in all three measurements." | 3.78 | [Differences in depression severity and frequency of relapses in opiate addicts treated with methadone or opiate blocker after detoxification]. ( Jovanović, T; Lazarević, D; Nikolić, G, 2012) |
| "Approximately 85% of patients receiving methadone maintenance therapy (MMT) for opiate dependence in the United States are infected with hepatitis C virus (HCV)." | 3.72 | A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipients. ( Atanda, A; Barnett, R; DePiano, M; Lynch, KG; Olthoff, KM; Weinrieb, RM, 2004) |
| "We describe a patient on methadone maintenance who developed distal leg edema after years of treatment." | 3.68 | Methadone and edema. ( Dhopesh, V; Manny, I; O'Conor, LM; Woody, G; Yeh, HS, 1991) |
| "The major predictors of substance use in the next five completed EMAs were substance use pattern over the current and prior five EMAs (no recent/current use, either recent or current use [but not both], continued use [both recent and current]), negative affect (feelings), and craving (rating)." | 2.87 | Using ecological momentary assessments to predict relapse after adult substance use treatment. ( Dennis, ML; Gustafson, DH; Scott, CK, 2018) |
| "While the best way to rid society of drug addiction is to prevent it from occurring in the first place, this is highly unlikely in the near future given the many ways that individuals can be first exposed to some potentially addicting substance." | 2.87 | Relapse prevention: Using sound to reduce the probability of recidivism and suffering following detoxification. ( Sewak, R; Spielholz, NI, 2018) |
| "Besides simply managing withdrawal symptoms, clinicians can further improve the care of patients with OUD through initiating maintenance treatment with MOUD, ideally with opioids used in the initial management of withdrawal." | 2.82 | Management of opioid withdrawal and initiation of medications for opioid use disorder in the hospital setting. ( Angermaier, G; Carswell, N; Castaneda, C; Delgado, F, 2022) |
| " A total of 554 heroin addicts in accordance with the inclusion criteria from 81 streets in 12 districts of Shanghai, China were divided into 4 groups: group 1--daily dosage taken orally of 60 mL of methadone or under combined with psychological counseling and social supports (n = 130); group 2--daily dosage taken orally of over 60 mL of methadone combined with psychological counseling and social supports (n = 50); group 3--JTT (Jitai tablets) combined with psychological counseling and social supports (n = 206); group 4--JTT combined with social supports (n = 168)." | 2.82 | Factors Associated with Relapse among Heroin Addicts: Evidence from a Two-Year Community-Based Follow-Up Study in China. ( Feng, XS; Jiang, HF; Rong, C; Zhang, J; Zhang, JC; Zhang, LJ; Zhang, RW, 2016) |
| "Other outcomes included SVR24, viral recurrence or reinfection, and adverse events." | 2.82 | Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial. ( Altice, F; Barr, E; Chen, E; Conway, B; Dalgard, O; Dore, GJ; Dutko, FJ; Gane, EJ; Gendrano, IN; Grebely, J; Howe, AY; Huang, HC; Litwin, AH; Luetkemeyer, A; Nahass, R; Nguyen, BY; Nickle, DC; Peng, CY; Platt, HL; Robertson, MN; Shibolet, O; Wahl, J, 2016) |
| "Opioid dependence has devastating and increasingly widespread consequences and costs, and the most common outcome of treatment is early relapse." | 2.82 | The effect of bundling medication-assisted treatment for opioid addiction with mHealth: study protocol for a randomized clinical trial. ( Alagoz, E; Gustafson, DH; Johnson, RA; Kornfield, R; Landucci, G; Mares, ML; McTavish, F; Pe-Romashko, K; Quanbeck, A; Shah, D; Thomas, C; Westergaard, RP, 2016) |
| "Methadone and Suboxone were highly and equally effective for preventing relapse to regular heroin use, with all but 3 of 37 (91." | 2.78 | Medically assisted recovery from opiate dependence within the context of the UK drug strategy: methadone and Suboxone (buprenorphine-naloxone) patients compared. ( Cockayne, L; McKeganey, N; Russell, C, 2013) |
| "Methadone maintenance treatment has been made available in China in response to the rapid spread of human immunodeficiency virus (HIV), but high rates of dropout and relapse are problematic." | 2.76 | Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China. ( Chang, YJ; Du, J; Evans, E; Hser, YI; Huang, D; Jiang, H; Li, J; Peng, C; Roll, J; Stitzer, ML; Wu, F; Zhang, B; Zhang, C; Zhang, R; Zhao, M, 2011) |
| "Buprenorphine has rarely been administered as an opioid agonist maintenance therapy in a correctional setting." | 2.74 | Buprenorphine and methadone maintenance in jail and post-release: a randomized clinical trial. ( Hershberger, J; Joseph, H; Lee, JD; Magura, S; Marsch, L; Rosenblum, A; Shropshire, C, 2009) |
| " Both dose-response and temporal associations of noncontingent voucher receipt with drug-positive urines were assessed." | 2.71 | Do noncontingent vouchers increase drug use? ( Epstein, DH; Gupman, AE; Preston, KL; Schroeder, JR; Umbricht, A, 2003) |
| "Methadone treatment was planned for no longer than 10 days while psychiatric supportive services were made available to continue as needed." | 2.64 | Outpatient vs hospital methadone detoxification: an experimental comparison. ( Elms, RR; Thomson, CP; Wilson, BK, 1975) |
| "This review extends a prior meta-analysis of acupuncture's utility for treating opioid detoxification, addressing the efficacy of acupuncture when combined with allopathic therapies." | 2.45 | A meta-analysis of acupuncture combined with opioid receptor agonists for treatment of opiate-withdrawal symptoms. ( Bao, YP; Epstein, DH; Liu, TT; Lu, L; Shi, J, 2009) |
| "Undertreatment of acute pain is suboptimal medical treatment, and patients receiving long-term OAT are at particular risk." | 2.43 | Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. ( Alford, DP; Compton, P; Samet, JH, 2006) |
| " We examined four dosing strategies: 1) increasing dose in response to participant-specific opioid use, 2) increasing dose weekly until some minimum dose (16 mg BUP, 100 mg methadone) was reached, 3) increasing dose weekly until some minimum and increasing dose in response to opioid use thereafter (referred to as the "hybrid strategy"), and 4) keeping dose constant after the first 2 weeks of treatment." | 1.72 | Buprenorphine & methadone dosing strategies to reduce risk of relapse in the treatment of opioid use disorder. ( Díaz, I; Fishman, M; Goodwin, ATS; Luo, S; Nunes, EV; Rotrosen, J; Rudolph, KE; Shulman, M; Williams, NT, 2022) |
| "Many people being treated for opioid use disorder continue to use drugs during treatment." | 1.56 | Beyond abstinence and relapse: cluster analysis of drug-use patterns during treatment as an outcome measure for clinical trials. ( Bertz, JW; Burgess-Hull, AJ; Epstein, DH; Kowalczyk, WJ; Panlilio, LV; Phillips, KA; Preston, KL; Stull, SW, 2020) |
| "Relapse was common (57%)." | 1.48 | Methadone maintenance treatment among patients exposed to illicit fentanyl in Rhode Island: Safety, dose, retention, and relapse at 6 months. ( Carroll, JJ; Green, TC; Rich, JD; Stone, AC, 2018) |
| "Methadone maintenance treatment physicians normalized most episodes as outpatients, often in collaboration with patients' primary care physicians." | 1.46 | Long QTc During Methadone Maintenance: Contributors and Interventions Over 4 Years. ( Batres-Y-Carr, T; Thuras, P; Westermeyer, J; Yoon, G, 2017) |
| "Methadone maintenance treatment (MMT) is recognized as one of the most effective treatments for heroin addiction but its effect is dimmed by the high incidence of heroin relapse." | 1.43 | Regional homogeneity changes between heroin relapse and non-relapse patients under methadone maintenance treatment: a resting-state fMRI study. ( Chang, H; Chen, J; Li, Q; Li, W; Li, Y; Li, Z; Liu, J; Shi, M; Wang, W; Wang, Y; Ye, J; Zhu, J, 2016) |
| "Methadone maintenance treatment has been subjected to much debate and controversy in Sweden during the last decades." | 1.39 | Excusing exclusion: Accounting for rule-breaking and sanctions in a Swedish methadone clinic. ( Petersson, FJ, 2013) |
| " The objective of this study involving 130 methadone-maintained outpatients receiving VBRT was to investigate whether resets (a) increase risk for adverse events (AEs) and (b) delay return to abstinence in relation to magnitude of voucher reset." | 1.36 | Resets do not appear to increase the rate of adverse events or prolong relapse in voucher-based reinforcement therapy. ( Bresani, E; Carpenedo, CM; Dugosh, KL; Kirby, KC; Rosenwasser, BJ; Versek, BE, 2010) |
| "Since this operation a recurrence of the displacement has not been observed and consecutively the filling of the pump could be accomplished without radiological investigations." | 1.36 | [Displaced pain pump because of a pendulous abdomen - dermatolipectomy as solution of the problem]. ( Föhn, M; Oehy, K; Vetter, M; Wedler, V, 2010) |
| "Heroin addiction is a complicated medical and psychiatric issue, with well-established as well as newer modes of treatment." | 1.35 | A 50-year-old woman addicted to heroin: review of treatment of heroin addiction. ( O'Brien, CP, 2008) |
| "Methadone maintenance treatment of opiate addiction is highly effective at reducing drug use, drug-related criminal activity, and risk of HIV transmission." | 1.33 | Linkage with methadone treatment upon release from incarceration: a promising opportunity. ( Clarke, J; Key, RG; McKenzie, M; Poshkus, M; Rich, JD; Shield, DC; Wolf, FA, 2005) |
| " Methadone dosage and frequency of methadone programme attendance in themselves were not significantly related to cessation of injecting." | 1.31 | Methadone maintenance and cessation of injecting drug use: results from the Amsterdam Cohort Study. ( Coutinho, RA; Langendam, MW; van Ameijden, EJ; van Brussel, GH, 2000) |
| " The modest increase in Amsterdam is explained by low background risk of overdose mortality, low starting dosage and the low threshold to treatment." | 1.31 | An increase in overdose mortality during the first 2 weeks after entering or re-entering methadone treatment in Amsterdam. ( Buster, MC; van Brussel, GH; van den Brink, W, 2002) |
| " Relapse rates were related to dosage level, client monitoring with urinalyses, and methadone take-home privileges in some clinics, and hence, these time-varying treatment events were important factors in treatment outcomes." | 1.29 | Treatment process and relapse to opioid use during methadone maintenance. ( Joe, GW; Sells, SB; Simpson, DD, 1994) |
| "Relapse is a central problem in the treatment of addictive behaviour, and a specific problem in the out-patient treatment of the opiate withdrawal syndrome." | 1.28 | Factors associated with relapse among opiate addicts in an out-patient detoxification programme. ( Gossop, M; Strang, J; Unnithan, S, 1992) |
| "A sample of 114 intravenous drug abusers hospitalized for HIV-spectrum diseases, was allowed to choose between methadone maintenance, partial or complete withdrawal as inpatient programs and was reassessed 4 days after discharge." | 1.28 | A prospective assessment of opiate addiction treatment protocols for inpatients with HIV-related syndromes. ( Di Giannantonio, M; Persico, AM; Tempesta, E, 1991) |
| "Seventy-eight opiate abusers were followed up after successful in-patient detoxification in order to examine renewed opiate use." | 1.28 | Circumstances surrounding the initial lapse to opiate use following detoxification. ( Bradley, BP; Gossop, M; Green, L; Phillips, G, 1989) |
| "It aims to examine drug addiction services in order to assess the interrelations between these services, their ways of operating and the use drug addicts make of them." | 1.27 | [Hospital emergencies in drug addiction. Analysis and interpretation of data recorded at 3 DEAs of the Turin area]. ( Furlan, PM; Meluzzi, A; Pelissero, E; Ravizza, L; Zanin, L, 1986) |
| "Relapse was prevented in BT, decreased in MBT, but was not prevented in M." | 1.26 | An evaluation of a behaviour therapy programme as an intervention treatment for the fear of withdrawal with heroin-dependent persons. ( Hollonds, GB; Oei, TP; Turecek, LR, 1980) |
| "A system of treatment for heroin addiction is proposed under the acronym STEPS (sequential treatment employing pharmacologic supports)." | 1.26 | Heroin addiction. Sequential treatment employing pharmacologic supports. ( Goldstein, A, 1976) |
| "Temporal patterns of drug abuse treatment reentry and other outcome measures were examined over a three-year period based on a national follow-up sample of persons admitted to treatment in the Drug Abuse Reporting Program (DARP) during 1969 to 1972." | 1.26 | Drug abuse treatment readmissions and outcomes. Three-year follow-up of DARP patients. ( Savage, LJ; Simpson, DD, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (25.88) | 18.7374 |
| 1990's | 34 (20.00) | 18.2507 |
| 2000's | 37 (21.76) | 29.6817 |
| 2010's | 44 (25.88) | 24.3611 |
| 2020's | 11 (6.47) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 6 |
| Hu, F | 3 |
| Li, W | 10 |
| Li, Q | 7 |
| Li, Y | 11 |
| Zhu, J | 9 |
| Wei, X | 4 |
| Yang, J | 3 |
| Guo, J | 1 |
| Qin, Y | 2 |
| Shi, H | 3 |
| Wang, W | 9 |
| Wang, Y | 14 |
| Idrissi Samlali, W | 1 |
| Ghailan, T | 1 |
| Karjouh, K | 1 |
| Ahami, AOT | 1 |
| Azzaoui, FZ | 1 |
| Chawar, C | 1 |
| Hillmer, A | 1 |
| Lamri, A | 1 |
| Kapczinski, F | 1 |
| Thabane, L | 1 |
| Pare, G | 1 |
| Samaan, Z | 1 |
| Carswell, N | 1 |
| Angermaier, G | 1 |
| Castaneda, C | 1 |
| Delgado, F | 1 |
| Wang, C | 3 |
| Fan, C | 1 |
| Lu, Q | 1 |
| Chen, W | 2 |
| Liu, Y | 10 |
| Xu, C | 2 |
| Tang, X | 1 |
| Zhou, W | 1 |
| Ling, L | 1 |
| Rudolph, KE | 1 |
| Williams, NT | 1 |
| Goodwin, ATS | 1 |
| Shulman, M | 1 |
| Fishman, M | 1 |
| Díaz, I | 1 |
| Luo, S | 1 |
| Rotrosen, J | 1 |
| Nunes, EV | 1 |
| Amini, Z | 1 |
| HeidariFarsani, E | 1 |
| Stöver, H | 2 |
| Jamin, D | 1 |
| Michels, II | 1 |
| Knorr, B | 1 |
| Keppler, K | 1 |
| Deimel, D | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 4 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 7 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Jiang, H | 2 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 2 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 4 |
| Chen, L | 2 |
| Yang, X | 1 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Gilson, E | 1 |
| Ye, J | 5 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 7 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Towards Ending HCV Infection Among Active Drug Users: a Community-based Intervention in Montpellier.[NCT04008927] | 554 participants (Actual) | Interventional | 2020-09-18 | Completed | |||
| Integrated Treatment of Hepatitis C Virus Infection Among Patients With Injecting Drug Abuse:a Randomised Controlled Trial (INTRO-HCV)[NCT03155906] | 240 participants (Anticipated) | Interventional | 2017-05-18 | Active, not recruiting | |||
| A Phase III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172/MK-8742 in Treatment-Naïve Subjects With Chronic HCV GT1, GT4, and GT6 Infection Who Are on Opiate Substitution Therapy[NCT02105688] | Phase 3 | 301 participants (Actual) | Interventional | 2014-09-02 | Completed | ||
| Impact on Opioid Use of Bundling Medication-assisted Treatment With mHealth[NCT02712034] | 417 participants (Actual) | Interventional | 2016-04-21 | Completed | |||
| Comparing Health & Social Outcomes Between Opioid-Dependent Individuals in Compulsory Drug Rehabilitation Centers and Voluntary Drug Treatment Clinics in Klang Valley, Malaysia[NCT02698098] | 281 participants (Actual) | Observational | 2012-08-31 | Terminated (stopped due to 1) Policy change affecting C&Cs; 2) interm analysis revealing overt differences) | |||
| SBIR Phase 1: Scalable Digital Delivery of Evidence-based Training for Family to Maximize Treatment Admission Rates of Opioid Use Disorder in Loved Ones-- We The Village Family Support Study[NCT04250077] | 45 participants (Actual) | Interventional | 2020-01-09 | Completed | |||
| Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics[NCT04706624] | 640 participants (Anticipated) | Interventional | 2020-11-02 | Active, not recruiting | |||
| Reducing HIV/AIDS and Drug Abuse Among Heroin Addicts Released From Compulsory Rehabilitation in China[NCT01270100] | 0 participants | Interventional | Completed | ||||
| Evaluating the Use of Sublingual Sufentanil in Patients With Suboxone Treatment Who Are Undergoing Ambulatory Surgery- a Case Series[NCT04716413] | Phase 4 | 3 participants (Actual) | Interventional | 2021-09-27 | Terminated (stopped due to Terminated early due to funding, lack of participants) | ||
| MOms in REcovery (MORE): Defining Optimal Care for Pregnant Women and Infants[NCT04251208] | 444 participants (Actual) | Observational | 2019-07-30 | Active, not recruiting | |||
| Four Models of Telephone Support for Stimulant Recovery[NCT00744068] | 302 participants (Actual) | Interventional | 2006-04-30 | Completed | |||
| A Randomized Community Intervention Trial on Reducing HIV Infection Among Drug Users Attending Methadone Maintenance Treatment(MMT) and Preventing Secondary Transmission From HIV Positive Clients to Their Sexual Partners in China[NCT01108614] | Phase 3 | 12,000 participants (Anticipated) | Interventional | 2009-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Blood was drawn from each participant to assess Hepatitis C Virus ribonucleic acid (HCV RNA) plasma levels using the Roche COBAS® AmpliPrep/COBAS® Taqman HCV Test, v2.0, which had a lower limit of quantification of 15 IU/mL. SVR12 was defined as HCV RNA below the lower limit of detection (
Timeframe: 12 weeks after end of all therapy (Study Week 24 for Immediate Treatment Arm and Study Week 40 for Deferred Treatment Arm)
| Intervention | Percentage of Participants (Number) |
|---|---|
| Immediate Treatment Arm: Grazoprevir/Elbasvir | 95.5 |
| Deferred Treatment Arm: Placebo > Grazoprevir/Elbasvir | 96.6 |
Blood was drawn from each participant to assess HCV RNA plasma levels using the Roche COBAS® AmpliPrep/COBAS® Taqman HCV Test, v2.0, which has an LLOQ of 15 IU/mL. SVR24 was defined as HCV RNA
Timeframe: 24 weeks after end of all therapy (Study Week 36 for Immediate Treatment Arm and Study Week 52 for Deferred Treatment Arm)
| Intervention | Percentage of Participants (Number) |
|---|---|
| Immediate Treatment Arm: Grazoprevir/Elbasvir | 94.1 |
| Deferred Treatment Arm: Placebo > Grazoprevir/Elbasvir | 96.5 |
An AE was defined as any untoward medical occurrence in a participant administered a pharmaceutical product and which did not necessarily have to have a causal relationship with this treatment. An AE could therefore be any unfavourable and unintended sign, symptom, or disease temporally associated with the use of a medicinal product or protocol-specified procedure, whether or not considered related to the medicinal product or protocol-specified procedure. Any worsening of a pre-existing condition that was temporally associated with the use of the Sponsor's product, was also an AE. For this outcome measure, the primary safety analysis compared the percentage of participants discontinuing study therapy due to an AE in the Immediate Treatment Arm during the double-blinded active treatment period to that of the Deferred Treatment Arm during the double-blinded placebo treatment period. (NCT02105688)
Timeframe: DB Treatment period (up to Study Week 12)
| Intervention | Percentage of Participants (Number) |
|---|---|
| Immediate Treatment Arm: Grazoprevir/Elbasvir | 0.5 |
| Deferred Treatment Arm: Placebo > Grazoprevir/Elbasvir | 1.0 |
An AE was defined as any untoward medical occurrence in a participant administered a pharmaceutical product and which did not necessarily have to have a causal relationship with this treatment. An AE could therefore be any unfavourable and unintended sign, symptom, or disease temporally associated with the use of a medicinal product or protocol-specified procedure, whether or not considered related to the medicinal product or protocol-specified procedure. Any worsening of a pre-existing condition that was temporally associated with the use of the Sponsor's product, was also an AE. For this outcome measure, the primary safety analysis compared the percentage of participants experiencing an AE in the Immediate Treatment Arm during the double-blinded active treatment period to that of the Deferred Treatment Arm during the double-blinded placebo treatment period. (NCT02105688)
Timeframe: DB Treatment period plus first 14 follow-up days (up to Study Week 14)
| Intervention | Percentage of Participants (Number) |
|---|---|
| Immediate Treatment Arm: Grazoprevir/Elbasvir | 83.1 |
| Deferred Treatment Arm: Placebo > Grazoprevir/Elbasvir | 83.0 |
Knowledge score calculated by adding the number of correct multiple-choice answers to 10 scenarios. Minimum score was 0 and maximum was 10. Higher scores reflect greater knowledge. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | 1.692307692 |
| CRAFT-C | 1.454545455 |
| PEER | 0.4 |
Total mood disturbance (TMD) score calculated by adding scores (1-5) from the tension (6 items), depression (8 items), anger (7 items), fatigue (5 items), and confusion (5 items) subscales, then subtracting the score form the vigor (6 items) subscale. Minimum TMD possible score was 1 and maximum was 149. Higher scores reflect greater mood disturbance. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | -43.1 |
| CRAFT-C | -28.8 |
| PEER | -3.916666667 |
Social Adjustment Scale, Self-Report. Standardized scale to assess individual's level of satisfaction in their role performance over the past two weeks key life areas. We used subscales representing the work, housework, and school areas of functioning. Each subscale consisted of 6 items scored on a 1-5 scale. A subscale adjustment score was obtained by summing the scores of all the items and dividing by the number of items actually answered. Thus, each subscale summary score had a minimum score of 1 and a maximum score of 5. Lower scores indicate higher satisfaction in their role performance. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | 0.5714285714 |
| CRAFT-C | -0.875 |
| PEER | 0.2222222222 |
The 5-item scale was transformed so that is had a mean of 50 and a s.d. of 10 in the general US population. Scores above and below 50 are above and below the average with each point representing a difference of 1/10th of a standard deviation. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | 0.23875 |
| CRAFT-C | 0.782613 |
| PEER | -1.238238333 |
The 7-item scale was transformed so that is had a mean of 50 and a s.d. of 10 in the general US population. Scores above and below 50 are above and below the average with each point representing a difference of 1/10th of a standard deviation. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | 5.309448182 |
| CRAFT-C | 0.192893 |
| PEER | -3.127840833 |
Participants reported whether their loved one had attended any treatment for their opioid problem since the last assessment by answering 8 questions regarding participation in treatment. Reports of new MAT and MAT at the follow-up assessment which was not reported at baseline were categorized as new MAT. In addition, reports of MAT entry to WTV staff were included. Outcome was the proportion of participants reporting that their loved one entered MAT. This differs from Outcome Measure 1 in that Outcome Measure 1 included drug-free and medication-assisted treatments of any type, while this measure included only MAT. (NCT04250077)
Timeframe: 3-month post study
| Intervention | Participants (Count of Participants) |
|---|---|
| CRAFT-A | 5 |
| CRAFT-C | 3 |
| PEER | 4 |
Global score from the 10-item scale was calculated by adding scores (1-10) from 10 items. Minimum possible score was 10 and maximum was 100. Higher scores reflect greater Relationship Happiness. (NCT04250077)
Timeframe: 3-month post study
| Intervention | units on a scale (Mean) |
|---|---|
| CRAFT-A | 21.54545455 |
| CRAFT-C | 23.3 |
| PEER | 1.5 |
Participants reported whether their loved one had attended any treatment for their opioid problem since the last assessment by answering 8 questions regarding participation in treatment (e.g., detox, any treatment, new treatment, MAT, new MAT, counseling, support group, and other group). Reports of new treatment, new MAT, and treatment at the follow-up assessment which were not reported at baseline were categorized as treatment entry. In addition, entry into WTV recovery coaching, WTV family coaching, or reports of treatment entry to WTV staff were categorized as treatment entry. Outcome was the proportion of participants reporting that their loved one entered new treatment. (NCT04250077)
Timeframe: 3-month post study
| Intervention | count of participants (Number) |
|---|---|
| CRAFT-A | 10 |
| CRAFT-C | 8 |
| PEER | 6 |
12 reviews available for methadone and Recrudescence
| Article | Year |
|---|---|
Management of opioid withdrawal and initiation of medications for opioid use disorder in the hospital setting.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Buprenorphine; Hospitals; Humans; Methadone; Naltr | 2022 |
Opioid substitution therapy for people living in German prisons-inequality compared with civic sector.
Topics: Delivery of Health Care; Female; Germany; Healthcare Disparities; Hepatitis C, Chronic; HIV Infectio | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Opioid Detoxification in Pregnancy: Systematic Review and Meta-Analysis of Perinatal Outcomes.
Topics: Analgesics, Opioid; Buprenorphine; Female; Humans; Infant, Newborn; Methadone; Neonatal Abstinence S | 2019 |
Pharmacotherapy for Substance Use Disorders.
Topics: Age Factors; Alcohol Deterrents; Alcoholism; Antidepressive Agents; Buprenorphine; Bupropion; Drug T | 2016 |
A meta-analysis of acupuncture combined with opioid receptor agonists for treatment of opiate-withdrawal symptoms.
Topics: Acupuncture Therapy; Adult; Analgesics, Opioid; Combined Modality Therapy; Humans; Male; Medicine, C | 2009 |
Methadone maintenance therapy in liver transplantation.
Topics: Analgesia; Contraindications; Drug Monitoring; Evidence-Based Practice; Feasibility Studies; Graft S | 2010 |
Acute pain management for patients receiving maintenance methadone or buprenorphine therapy.
Topics: Acute Disease; Adult; Analgesics, Opioid; Buprenorphine; Female; Heroin Dependence; Humans; Methadon | 2006 |
Opioid addiction and incarceration: an overview.
Topics: Analgesics, Opioid; Chronic Disease; Criminal Law; Forensic Psychiatry; Humans; Methadone; Opioid-Re | 2007 |
[Naltrexone--prevention of recurrence in narcotic dependence and in alcoholism].
Topics: Alcoholism; Delayed-Action Preparations; Follow-Up Studies; Heroin Dependence; Humans; Methadone; Na | 1996 |
Pharmacologic treatments for drug and alcohol dependence.
Topics: Alcohol Deterrents; Alcoholism; Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Cocaine- | 1999 |
[Methadone maintenance as a therapeutic approach in the treatment of opiate dependent patients].
Topics: Follow-Up Studies; Germany; Humans; Methadone; Opioid-Related Disorders; Recurrence | 1991 |
21 trials available for methadone and Recrudescence
| Article | Year |
|---|---|
Investigating the effect of zinc supplementation on probability of relapse and mental health in patients with opioid use disorder undergoing methadone maintenance treatment.
Topics: Dietary Supplements; Humans; Iran; Mental Health; Methadone; Opiate Substitution Treatment; Opioid-R | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Using ecological momentary assessments to predict relapse after adult substance use treatment.
Topics: Adult; Affective Symptoms; Ambulatory Care; Chicago; Craving; Ecological Momentary Assessment; Femal | 2018 |
Relapse prevention: Using sound to reduce the probability of recidivism and suffering following detoxification.
Topics: Adult; Analgesics, Opioid; Behavior, Addictive; Brain; Female; Florida; Humans; Male; Methadone; Mid | 2018 |
Factors Associated with Relapse among Heroin Addicts: Evidence from a Two-Year Community-Based Follow-Up Study in China.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; China; Cohort Studies; Combined Modality Therapy; Couns | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Benzofurans; Buprenorphine; Buprenorphine, Naloxone Drug | 2016 |
The effect of bundling medication-assisted treatment for opioid addiction with mHealth: study protocol for a randomized clinical trial.
Topics: Adaptation, Psychological; Analgesics, Opioid; Buprenorphine; Clinical Protocols; Combined Modality | 2016 |
The effect of stress on craving for methadone depends on the timing of last methadone dose.
Topics: Behavior, Addictive; Cold Temperature; Female; Heroin Dependence; Humans; Male; Methadone; Middle Ag | 2008 |
Buprenorphine and methadone maintenance in jail and post-release: a randomized clinical trial.
Topics: Adolescent; Adult; Aged; Buprenorphine; Diagnosis, Dual (Psychiatry); Female; Follow-Up Studies; HIV | 2009 |
Cue-induced reactivity, cortisol response and substance use outcome in treated heroin dependent individuals.
Topics: Adult; Buprenorphine; Cues; Drug-Seeking Behavior; Female; Galvanic Skin Response; Heroin Dependence | 2011 |
Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China.
Topics: Adult; Analysis of Variance; China; Female; HIV Infections; Humans; Male; Methadone; Narcotic Antago | 2011 |
Pilot trial of a recovery management intervention for heroin addicts released from compulsory rehabilitation in China.
Topics: Adult; China; Employment; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Mandatory Prog | 2013 |
Medically assisted recovery from opiate dependence within the context of the UK drug strategy: methadone and Suboxone (buprenorphine-naloxone) patients compared.
Topics: Adult; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Female; Follow-Up Studies; Health Po | 2013 |
Do noncontingent vouchers increase drug use?
Topics: Adult; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; | 2003 |
In-patient detoxification procedures, treatment retention, and post-treatment opiate use: comparison of lofexidine + naloxone, lofexidine + placebo, and methadone.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Clonidine; Cohort Studies; Double- | 2007 |
The Swedish methadone maintenance program: a controlled study.
Topics: Adult; Female; Heroin Dependence; Humans; Male; Methadone; Recurrence; Sweden | 1981 |
Investigating the influence of treatment philosophy on outcome of methadone maintenance.
Topics: Adult; Aftercare; Cohort Studies; Dose-Response Relationship, Drug; Female; Heroin Dependence; Human | 1995 |
Outcome after methadone treatment: influence of prior treatment factors and current treatment status.
Topics: Adult; Combined Modality Therapy; Dose-Response Relationship, Drug; Double-Blind Method; Drug Admini | 1994 |
Mazindol for relapse prevention to cocaine abuse in methadone-maintained patients.
Topics: Adult; Cocaine; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; H | 1995 |
Patterns of opiate use in a heroin maintenance programme.
Topics: Adult; Age Factors; Anti-Anxiety Agents; Clorazepate Dipotassium; Female; Follow-Up Studies; Heroin | 2000 |
Outpatient vs hospital methadone detoxification: an experimental comparison.
Topics: Administration, Oral; Adult; Ambulatory Care; Aspartate Aminotransferases; Costs and Cost Analysis; | 1975 |
138 other studies available for methadone and Recrudescence
| Article | Year |
|---|---|
Relapse risk revealed by degree centrality and cluster analysis in heroin addicts undergoing methadone maintenance treatment.
Topics: Brain; Heroin; Heroin Dependence; Humans; Male; Methadone; Opiate Substitution Treatment; Recurrence | 2023 |
[Early maladaptive schemes and relapse during methadone maintenance treatment among drug addicts (a cognitive approach)].
Topics: Adaptation, Psychological; Cognition; Cross-Sectional Studies; Drug Users; Female; Heroin Dependence | 2022 |
Implications of OPRM1 and CYP2B6 variants on treatment outcomes in methadone-maintained patients in Ontario: Exploring sex differences.
Topics: Adult; Alleles; Analgesics, Opioid; Cytochrome P-450 CYP2B6; Female; Gene Frequency; Genotype; Human | 2021 |
Exploration of dose tapering strategies for methadone maintenance treatment based on relapse risks: A subpopulation treatment effect pattern plot (STEPP) analysis.
Topics: China; Drug Tapering; Humans; Methadone; Opiate Substitution Treatment; Recurrence; Retrospective St | 2022 |
Buprenorphine & methadone dosing strategies to reduce risk of relapse in the treatment of opioid use disorder.
Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Humans; Methadone; Narc | 2022 |
Beyond abstinence and relapse: cluster analysis of drug-use patterns during treatment as an outcome measure for clinical trials.
Topics: Adult; Behavior Therapy; Clinical Trials as Topic; Cluster Analysis; Cocaine-Related Disorders; Fema | 2020 |
A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children.
Topics: Adolescent; Aftercare; Analgesics, Opioid; Child; Child, Preschool; Female; Hospitalization; Humans; | 2021 |
Altered brain intrinsic functional hubs and connectivity associated with relapse risk in heroin dependents undergoing methadone maintenance treatment: A resting-state fMRI study.
Topics: Adult; Brain; Brain Mapping; Cerebral Cortex; Chronic Disease; Female; Heroin; Heroin Dependence; Hu | 2021 |
Beyond abstinence and relapse II: momentary relationships between stress, craving, and lapse within clusters of patients with similar patterns of drug use.
Topics: Affect; Buprenorphine; Cocaine-Related Disorders; Craving; Ecological Momentary Assessment; Female; | 2021 |
A qualitative assessment of an abstinence-oriented therapeutic community for prisoners with substance use disorders in Kyrgyzstan.
Topics: Adult; Attitude; Female; Humans; Kyrgyzstan; Male; Methadone; Middle Aged; Opiate Substitution Treat | 2017 |
Long QTc During Methadone Maintenance: Contributors and Interventions Over 4 Years.
Topics: Adult; Aged; Analgesics, Opioid; Electrocardiography; Humans; Long QT Syndrome; Male; Methadone; Mid | 2017 |
Methadone maintenance treatment among patients exposed to illicit fentanyl in Rhode Island: Safety, dose, retention, and relapse at 6 months.
Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Overdose; Female; Fentanyl; Humans | 2018 |
The polymorphism of dopamine D2 receptor TaqIA gene is associated with brain response to drug cues in male heroin-dependent individuals during methadone maintenance treatment.
Topics: Adult; Alleles; Analgesics, Opioid; Brain; Craving; Cues; Heroin; Heroin Dependence; Humans; Magneti | 2019 |
Mixed methods to explore factors associated with the decline of patients in the methadone maintenance treatment program in Shanghai, China.
Topics: Adolescent; Adult; Aged; Amphetamine-Related Disorders; Analgesics, Opioid; China; Female; Focus Gro | 2019 |
Daily temporal patterns of heroin and cocaine use and craving: relationship with business hours regardless of actual employment status.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Analgesics, Opioid; Cocaine-Related Disorders; | 2013 |
Syncope: a tale of two triggers.
Topics: Bradycardia; Dose-Response Relationship, Drug; Electrocardiography; Humans; Male; Methadone; Middle | 2013 |
Excusing exclusion: Accounting for rule-breaking and sanctions in a Swedish methadone clinic.
Topics: Analgesics, Opioid; Attitude of Health Personnel; Cooperative Behavior; Dangerous Behavior; Decision | 2013 |
[Outcomes of comprehensive inpatient opiate detoxification in patients re-admitted to treatment within one year].
Topics: Adult; Aftercare; Clonidine; Comorbidity; Comprehensive Health Care; Female; Germany; Heroin Depende | 2015 |
Relationship between addiction relapse and self-efficacy rates in injection drug users referred to Maintenance Therapy Center of Sari, 1391.
Topics: Adult; Age Factors; Cross-Sectional Studies; Female; Humans; Iran; Male; Methadone; Middle Aged; Opi | 2014 |
Methadone maintenance treatment may improve completion rates and delay opioid relapse for opioid dependent individuals under community corrections supervision.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Criminal Law; Criminals; Female; Humans; Interviews | 2014 |
Predicting subsequent relapse by drug-related cue-induced brain activation in heroin addiction: an event-related functional magnetic resonance imaging study.
Topics: Adult; Brain; Brain Mapping; China; Cues; Female; Follow-Up Studies; Heroin Dependence; History, Anc | 2015 |
Methadone maintenance patients show a selective deficit to reverse positive outcomes in drug-related conditions compared to medication free prolonged opiate abstinence.
Topics: Adult; Analgesics, Opioid; Behavior, Addictive; Female; Humans; Male; Methadone; Middle Aged; Opiate | 2014 |
Compulsory drug detention and injection drug use cessation and relapse in Bangkok, Thailand.
Topics: Adult; Cross-Sectional Studies; Female; Health Policy; HIV Infections; Humans; Logistic Models; Male | 2015 |
[Treatment of chronic hepatitis C in drug users: ethic, successful and useful].
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Buprenorphine; Comorbidity; Cooperative Beh | 2014 |
Risk Factors for Relapse and Higher Costs Among Medicaid Members with Opioid Dependence or Abuse: Opioid Agonists, Comorbidities, and Treatment History.
Topics: Adult; Analgesics, Opioid; Behavior Therapy; Buprenorphine; Combined Modality Therapy; Comorbidity; | 2015 |
Dysfunctional Default Mode Network in Methadone Treated Patients Who Have a Higher Heroin Relapse Risk.
Topics: Adult; Brain; Brain Mapping; Female; Follow-Up Studies; Heroin Dependence; Humans; Magnetic Resonanc | 2015 |
Brain white matter integrity in heroin addicts during methadone maintenance treatment is related to relapse propensity.
Topics: Adult; Brain; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Follow-Up Studies; Her | 2016 |
Regional homogeneity changes between heroin relapse and non-relapse patients under methadone maintenance treatment: a resting-state fMRI study.
Topics: Adult; Aftercare; Biomarkers; Brain; Brain Mapping; Caudate Nucleus; Heroin Dependence; Humans; Magn | 2016 |
Relapse to opioid use in opioid-dependent individuals released from compulsory drug detention centres compared with those from voluntary methadone treatment centres in Malaysia: a two-arm, prospective observational study.
Topics: Adolescent; Adult; Analgesics, Opioid; Counseling; Humans; Malaysia; Mandatory Programs; Methadone; | 2017 |
A 50-year-old woman addicted to heroin: review of treatment of heroin addiction.
Topics: Buprenorphine; Drug Therapy, Combination; Female; Heroin Dependence; History, 19th Century; History, | 2008 |
Peginterferon plus Ribavirin for chronic hepatitis C in opiate addicts on methadone/buprenorphine maintenance therapy.
Topics: Adolescent; Adult; Antiviral Agents; Buprenorphine; Drug Therapy, Combination; Female; Hepatitis C, | 2009 |
Character pathology and neuropsychological test performance in remitted opiate dependence.
Topics: Adult; Character; Female; Humans; Male; Methadone; Middle Aged; Neuropsychological Tests; Opioid-Rel | 2008 |
Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use.
Topics: Adult; Affect; Ambulatory Care; Cocaine-Related Disorders; Combined Modality Therapy; Computers, Han | 2009 |
Maintenance therapy and 3-year outcome of opioid-dependent prisoners: a prospective study in France (2003-06).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Buprenorphine; Female; France; Humans; Male; Methadone; | 2009 |
Gender difference in the treatment outcome of patients served in the mixed-gender program.
Topics: Adolescent; Adult; Female; Humans; Male; Methadone; Opioid-Related Disorders; Recurrence; Sex Factor | 2009 |
Proportional hazards frailty models for recurrent methadone maintenance treatment.
Topics: Adult; Analgesics, Opioid; British Columbia; Confidence Intervals; Databases, Factual; Female; Heroi | 2009 |
A delayed methadone encephalopathy: clinical and neuroradiological findings.
Topics: Brain; Child, Preschool; Encephalitis; Female; Humans; Magnetic Resonance Imaging; Methadone; Neurol | 2010 |
Premature discharge from methadone treatment: patient perspectives.
Topics: Adult; Appointments and Schedules; Counseling; Crime; Ethnicity; Female; Heroin Dependence; Humans; | 2009 |
[Displaced pain pump because of a pendulous abdomen - dermatolipectomy as solution of the problem].
Topics: Abdominal Fat; Adult; Amides; Analgesics, Opioid; Chronic Disease; Equipment Failure Analysis; Femal | 2010 |
Daily life hour by hour, with and without cocaine: an ecological momentary assessment study.
Topics: Adult; Affect; Cocaine; Cocaine-Related Disorders; Cohort Studies; Computers, Handheld; Female; Hero | 2010 |
Resets do not appear to increase the rate of adverse events or prolong relapse in voucher-based reinforcement therapy.
Topics: Adult; Cocaine-Related Disorders; Female; Humans; Male; Methadone; Middle Aged; Proportional Hazards | 2010 |
Medical treatment of opioid dependence within the South African context.
Topics: Buprenorphine; Drug Combinations; Drug Overdose; Humans; Methadone; Motivation; Naloxone; Narcotic A | 2010 |
Lapse and relapse following inpatient treatment of opiate dependence.
Topics: Adolescent; Adult; Aftercare; Age Factors; Analgesics, Opioid; Female; Follow-Up Studies; Humans; In | 2010 |
Addiction treatment in Russia.
Topics: Behavior, Addictive; Buprenorphine; Delayed-Action Preparations; Humans; Methadone; Naltrexone; Narc | 2010 |
Effect of prison-based opioid substitution treatment and post-release retention in treatment on risk of re-incarceration.
Topics: Adolescent; Adult; Humans; Longitudinal Studies; Male; Methadone; Narcotics; New South Wales; Opiate | 2012 |
[Differences in depression severity and frequency of relapses in opiate addicts treated with methadone or opiate blocker after detoxification].
Topics: Adult; Depression; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Su | 2012 |
Association between cholesterol plasma levels and craving among heroin users.
Topics: Adult; Body Mass Index; Cholesterol; Female; Heroin; Heroin Dependence; Humans; Male; Methadone; Mid | 2012 |
An increase in overdose mortality during the first 2 weeks after entering or re-entering methadone treatment in Amsterdam.
Topics: Adult; Cohort Studies; Drug Overdose; Female; Heroin; Heroin Dependence; Humans; Male; Methadone; Na | 2002 |
[Frequency of re-incarcerations in the same detention center: role of substitution therapy. A preliminary retrospective analysis].
Topics: Adult; Buprenorphine; Female; France; Heroin Dependence; Humans; Male; Methadone; Narcotic Antagonis | 2002 |
Why do so many drug users smoke?
Topics: Adult; Causality; Comorbidity; Cross-Sectional Studies; Female; Focus Groups; Health Surveys; Heroin | 2003 |
Predictors of drug treatment re-entry following relapse to cocaine use in DATOS.
Topics: Adult; Ambulatory Care; Black People; Cocaine-Related Disorders; Female; Follow-Up Studies; Humans; | 2003 |
A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipients.
Topics: Adult; Analgesics, Opioid; Comorbidity; Female; Hepatitis C; Humans; Liver Cirrhosis; Liver Transpla | 2004 |
Cycling in and out of treatment; participation in methadone treatment in NSW, 1990-2002.
Topics: Adult; Clinical Trials as Topic; Cohort Studies; Female; Heroin Dependence; Humans; Long-Term Care; | 2006 |
Linkage with methadone treatment upon release from incarceration: a promising opportunity.
Topics: Crime; Health Services Needs and Demand; Hepatitis B; Hepatitis C; HIV Infections; Humans; Long-Term | 2005 |
Longitudinal predictors of injection cessation and subsequent relapse among a cohort of injection drug users in Baltimore, MD, 1988-2000.
Topics: Adult; Baltimore; Cohort Studies; Female; HIV Infections; Humans; Ill-Housed Persons; Incidence; Lon | 2006 |
How do treatment repeaters use the drug treatment system? An analysis of injection drug users in Massachusetts.
Topics: Adult; Female; Humans; Inactivation, Metabolic; Longitudinal Studies; Male; Massachusetts; Mental He | 2006 |
Determinants of health-related quality of life of opiate users at entry to low-threshold methadone programs.
Topics: Adolescent; Adult; Child Abuse; Child Abuse, Sexual; Cocaine-Related Disorders; Comorbidity; Female; | 2006 |
Antidepressant treatment patterns in a novel methadone maintenance clinic targeting young adults an observational study.
Topics: Adolescent; Adult; Age Factors; Aged; Antidepressive Agents; Dose-Response Relationship, Drug; Drug | 2006 |
Relapse to opioid use after treatment of chronic hepatitis C with pegylated interferon and ribavirin.
Topics: Antiviral Agents; Behavior, Addictive; Cocaine-Related Disorders; Comorbidity; Drug Administration S | 2006 |
Mood disorders affect drug treatment success of drug-dependent pregnant women.
Topics: Adult; Diagnosis, Dual (Psychiatry); Diagnostic and Statistical Manual of Mental Disorders; Female; | 2007 |
Problem drinking in relation to treatment outcome among opiate addicts in methadone maintenance treatment.
Topics: Adult; Alcohol Deterrents; Alcoholism; Comorbidity; Cyanamide; Disulfiram; Female; Follow-Up Studies | 2007 |
Chronic methadone treatment and repeated withdrawal impair cognition and increase the expression of apoptosis-related proteins in mouse brain.
Topics: Animals; Apoptosis Regulatory Proteins; Brain; Dose-Response Relationship, Drug; Male; Maze Learning | 2007 |
An evaluation of a behaviour therapy programme as an intervention treatment for the fear of withdrawal with heroin-dependent persons.
Topics: Adult; Assertiveness; Behavior Therapy; Desensitization, Psychologic; Fear; Female; Follow-Up Studie | 1980 |
Use of naltrexone to extinguish opioid-conditioned responses.
Topics: Adult; Combined Modality Therapy; Conditioning, Classical; Extinction, Psychological; Heroin Depende | 1984 |
Episodes of heroin use during maintenance treatment with stable dosage of (-)-alpha-acetylmethadol (methadyl acetate, LAAM).
Topics: Family; Heroin; Heroin Dependence; Humans; Life Style; Methadone; Methadyl Acetate; Recurrence | 1983 |
[Apropos of the Ministerial Order regulating methadone treatment].
Topics: Heroin Dependence; Humans; Legislation, Drug; Methadone; Recurrence; Rehabilitation Centers; Spain | 1983 |
Shutting off methadone. Costs and benefits.
Topics: Cost-Benefit Analysis; Crime; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; | 1981 |
Relapse in opiate addicts: a behavioral analysis.
Topics: Adult; Cues; Humans; Interpersonal Relations; Male; Methadone; Motivation; Opioid-Related Disorders; | 1982 |
Stressful life events and the return to heroin use.
Topics: Depression; Heroin Dependence; Humans; Life Change Events; Methadone; Recurrence | 1981 |
Drug abuse treatment readmissions and outcomes. Three-year follow-up of DARP patients.
Topics: Adolescent; Adult; Humans; Methadone; Outcome and Process Assessment, Health Care; Recurrence; Socia | 1980 |
Conditioned responses to drug-related stimuli: is context crucial?
Topics: Adult; Conditioning, Classical; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Recurr | 1995 |
[Report on the buprenorphine substitution experience in urban medicine in Belgium].
Topics: Belgium; Buprenorphine; Drug Prescriptions; France; Heroin Dependence; Humans; Methadone; Physicians | 1994 |
[Can substitution practices be indicated in withdrawal programs for heroin addicts?].
Topics: Buprenorphine; Heroin Dependence; Humans; Inpatients; Methadone; Narcotics; Outpatients; Patient Com | 1994 |
Treatment process and relapse to opioid use during methadone maintenance.
Topics: Adult; Comorbidity; Female; Follow-Up Studies; Humans; Male; Methadone; Opioid-Related Disorders; Ou | 1994 |
Methadone maintenance in general practice: patients, workload, and outcomes.
Topics: Adult; Benzodiazepines; Counseling; Family Practice; Female; Humans; Male; Methadone; Narcotics; Pat | 1994 |
Phases of treatment: a practical approach to methadone maintenance treatment.
Topics: Combined Modality Therapy; Health Care Rationing; Heroin Dependence; Humans; Long-Term Care; Methado | 1994 |
A 24-year follow-up of California narcotics addicts.
Topics: Adult; California; Cause of Death; Drug Overdose; Employment; Follow-Up Studies; Health Status; Huma | 1993 |
Correlates of drug injection behaviors among methadone outpatients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cocaine; Female; Health Knowledge, Attitudes, Practice; H | 1993 |
Exposure to methadone programs and heroin use.
Topics: Adult; Female; Heroin Dependence; Humans; Length of Stay; Male; Methadone; Outcome and Process Asses | 1993 |
Treatment effectiveness for legally coerced versus voluntary methadone maintenance clients.
Topics: Adult; California; Commitment of Mentally Ill; Crime; Female; Follow-Up Studies; Heroin Dependence; | 1993 |
Methadone maintenance and recovery.
Topics: Follow-Up Studies; Heroin Dependence; Humans; Methadone; Opioid-Related Disorders; Outcome and Proce | 1993 |
Treatment outcomes for methadone clients receiving lump-sum payments at initiation of disability benefits.
Topics: Adult; Ambulatory Care; Cocaine; Disability Evaluation; Eligibility Determination; Female; Financial | 1996 |
Reducing parental risk factors for children's substance misuse: preliminary outcomes with opiate-addicted parents.
Topics: Adolescent; Adult; Child; Child of Impaired Parents; Child, Preschool; Cohort Studies; Female; Heroi | 1997 |
Temporal patterns of heroin and cocaine use among methadone patients.
Topics: Adult; Age Factors; Analysis of Variance; Cluster Analysis; Cocaine-Related Disorders; Crime; Female | 1998 |
[Ambulatory opiate withdrawal].
Topics: Ambulatory Care; Buprenorphine; Hospitalization; Humans; Methadone; Narcotics; Opioid-Related Disord | 1998 |
Prior treatment history and its impact on criminal recidivism.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Cocaine-Related Disorders; Combined Modality The | 1999 |
Community reinforcement approach for combined opioid and cocaine dependence. Patterns of engagement in alternate activities.
Topics: Adult; Buprenorphine; Clinical Trials as Topic; Cocaine-Related Disorders; Community Networks; Couns | 2000 |
Methadone maintenance and cessation of injecting drug use: results from the Amsterdam Cohort Study.
Topics: Adolescent; Adult; Cohort Studies; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; | 2000 |
Factors predicting entry of injecting drug users into substance abuse treatment.
Topics: Adolescent; Adult; Comorbidity; Factor Analysis, Statistical; Female; Heroin Dependence; HIV Infecti | 2000 |
Changes in Millon Clinical Multiaxial Inventory scores among opiate addicts as a function of retention in methadone maintenance treatment and recent drug use.
Topics: Adult; Antisocial Personality Disorder; Anxiety Disorders; Female; Follow-Up Studies; Humans; Male; | 2000 |
The Key Extended Entry Program (KEEP): a methadone treatment program for opiate-dependent inmates.
Topics: Female; Heroin Dependence; Humans; Male; Methadone; Narcotics; Patient Selection; Prisoners; Recurre | 2001 |
Risk factors associated with noncompliance with methadone substitution therapy (MST) and relapse among chronic opiate users in an Outer London community.
Topics: Adult; England; Female; Humans; Male; Methadone; Middle Aged; Motivation; Opioid-Related Disorders; | 2001 |
Conditioned heroin responses as an indication of readdiction liability.
Topics: Conditioning, Psychological; Heart Rate; Heroin Dependence; Humans; Methadone; Projective Techniques | 1979 |
Naltrexone in the treatment of opiate dependence.
Topics: Adolescent; Adult; Follow-Up Studies; Forecasting; Heroin Dependence; Humans; Male; Methadone; Nalox | 1978 |
Therapeutic detoxification of adolescent heroin addicts.
Topics: Adolescent; Age Factors; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; New | 1978 |
Methadone maintenance: long-term follow-up of detoxified patients.
Topics: Alcoholism; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Methadone; New Yor | 1978 |
Detoxification from methadone maintenance: risk factors associated with relapse to narcotic use.
Topics: Adult; Female; Humans; Male; Methadone; New York City; Prognosis; Recurrence; Risk; Substance-Relate | 1978 |
Long-term outcome of patients treated with methadone maintenance.
Topics: Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Methadone; New York City; Prog | 1978 |
Ability to remain abstinent after methadone detoxification. A six-year study.
Topics: Ethnicity; Female; Follow-Up Studies; Humans; Male; Methadone; New York City; Recurrence; Remission, | 1977 |
Evaluation methodology.
Topics: Behavior; Crime; Employment; Evaluation Studies as Topic; Heroin Dependence; Humans; Interpersonal R | 1977 |
Evaluation of the 21-day outpatient heroin detoxification.
Topics: Adolescent; Adult; Counseling; Evaluation Studies as Topic; Heroin Dependence; Humans; Male; Methado | 1977 |
Successful detoxification from methadone maintenance. Follow-up study of 38 patients.
Topics: Alcoholism; Drug Evaluation; Humans; Methadone; Recurrence; Social Adjustment; Substance Withdrawal | 1976 |
Experiences of a methadone detoxification programme for opium addicts.
Topics: Adult; Aged; Humans; Male; Methadone; Middle Aged; Opium; Recurrence; Substance-Related Disorders | 1976 |
Criminal activity, wages earned, and drug use after two years of methadone treatment.
Topics: Alcohol Drinking; California; Criminal Psychology; Employment; Humans; Income; Male; Methadone; Pati | 1975 |
Methadone dependence in the rat.
Topics: Animals; Body Weight; Humans; Male; Mathematics; Methadone; Rats; Recurrence; Substance Withdrawal S | 1975 |
Heroin addiction. Sequential treatment employing pharmacologic supports.
Topics: Heroin Dependence; Humans; Methadone; Morphine; Naltrexone; Prognosis; Recurrence | 1976 |
Factors associated with relapse among opiate addicts in an out-patient detoxification programme.
Topics: Adult; Ambulatory Care; Female; Heroin Dependence; Humans; Male; Methadone; Opioid-Related Disorders | 1992 |
Improving treatment outcome in pregnant opiate-dependent women.
Topics: Adult; Combined Modality Therapy; Female; Fetal Growth Retardation; Follow-Up Studies; Heroin; Heroi | 1992 |
[Critical comments on the contribution by N. Scherbaum and N. Gaspar. Substitution with methadone as a therapeutic approach in the treatment of drug dependent patients].
Topics: Follow-Up Studies; Heroin Dependence; Humans; Long-Term Care; Methadone; Opioid-Related Disorders; R | 1992 |
Social support and relapse: commonalities among alcoholics, opiate users, and cigarette smokers.
Topics: Adult; Alcoholism; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Opioid-Related D | 1991 |
Methadone maintenance and clonidine detoxification in the treatment of opiate addicts in Israel: suggesting evidence for cultural differences in the effectiveness of treatment modalities for opiate addiction.
Topics: Antidepressive Agents; Clonidine; Combined Modality Therapy; Cross-Cultural Comparison; Culture; Emp | 1991 |
[The treatment of dependence in the therapeutic community].
Topics: Belgium; Female; Follow-Up Studies; Humans; Life Style; Male; Methadone; Recurrence; Substance Abuse | 1990 |
Ineffective use of psychoactive drugs. Methadone treatment is no exception.
Topics: Humans; Methadone; Recurrence; Substance-Related Disorders; Treatment Outcome; Treatment Refusal | 1992 |
Methadone and edema.
Topics: Adult; Dose-Response Relationship, Drug; Edema; Heroin Dependence; Humans; Male; Methadone; Recurren | 1991 |
A prospective assessment of opiate addiction treatment protocols for inpatients with HIV-related syndromes.
Topics: Adult; Combined Modality Therapy; Female; Follow-Up Studies; Heroin Dependence; HIV Infections; Hosp | 1991 |
Unmet service needs in methadone maintenance.
Topics: Combined Modality Therapy; Community Mental Health Services; Consumer Behavior; Follow-Up Studies; H | 1991 |
Risk characteristics associated with chronic unemployment in methadone clients.
Topics: Adult; Female; Heroin Dependence; Humans; Male; Methadone; Recurrence; Rehabilitation, Vocational; R | 1990 |
[Therapeutic treatment of drug dependence during hospital recovery].
Topics: Age Factors; Follow-Up Studies; Heroin Dependence; Hospitalization; Humans; Italy; Length of Stay; M | 1990 |
Lapse, relapse and survival among opiate addicts after treatment. A prospective follow-up study.
Topics: Adolescent; Adult; England; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; O | 1989 |
Circumstances surrounding the initial lapse to opiate use following detoxification.
Topics: Adolescent; Adult; Cues; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Opio | 1989 |
Cue exposure as an assessment technique in the management of a heroin addict: case report.
Topics: Adult; Arousal; Cues; Galvanic Skin Response; Heroin Dependence; Humans; Male; Methadone; Recurrence | 1989 |
Classically conditioned responses in opioid and cocaine dependence: a role in relapse?
Topics: Cocaine; Conditioning, Classical; Humans; Methadone; Opioid-Related Disorders; Random Allocation; Re | 1988 |
Survival analysis in drug program evaluation. Part I. Overall program effectiveness.
Topics: Adult; Crime; Employment; Heroin Dependence; Humans; Male; Methadone; Outcome and Process Assessment | 1987 |
Survival analysis in drug program evaluation. Part II. Partitioning treatment effects.
Topics: Crime; Humans; Methadone; Opioid-Related Disorders; Patient Compliance; Prognosis; Recurrence; Stati | 1987 |
The antecedents and benefits of achieving abstinence in opioid addicts: a 2.5-year follow-up study.
Topics: Adult; Combined Modality Therapy; Female; Follow-Up Studies; Hospitals, University; Humans; Male; Me | 1987 |
Fear of methadone maintenance.
Topics: Attitude to Health; Fear; Humans; Methadone; Opioid-Related Disorders; Outcome and Process Assessmen | 1987 |
[Hospital emergencies in drug addiction. Analysis and interpretation of data recorded at 3 DEAs of the Turin area].
Topics: Adolescent; Adult; Emergencies; Emergency Service, Hospital; Female; Humans; Italy; Male; Methadone; | 1986 |
Field observations of a heroin addict: a case study.
Topics: Activities of Daily Living; Adult; Behavior; Criminal Psychology; Drinking Behavior; Heroin Dependen | 1974 |
The ability to remain abstinent upon leaving methadone maintenance: a prospective study.
Topics: Adult; Age Factors; Ethnicity; Female; Heroin Dependence; Humans; Male; Methadone; Patient Dropouts; | 1974 |
Heroin addiction and the role of methadone in its treatment.
Topics: Animals; Anxiety; Compulsive Behavior; Conditioning, Classical; Conditioning, Operant; Dogs; Drug To | 1972 |
Methadone maintenance: myth and reality.
Topics: Costs and Cost Analysis; Criminal Psychology; Drug Tolerance; Evaluation Studies as Topic; Heroin; H | 1972 |
Editorial: Detoxification of methadone patients, and public policy.
Topics: Chronic Disease; Follow-Up Studies; Humans; Methadone; Politics; Recurrence; Substance Withdrawal Sy | 1973 |
Recent developments in the therapy of addictions.
Topics: Amphetamine; Aversive Therapy; Barbiturates; Cocaine; Hallucinogens; Humans; Methadone; Nicotiana; O | 1972 |
Maintenance methadone treatment of drug dependency.
Topics: Administration, Oral; Adult; Constipation; Erectile Dysfunction; Evaluation Studies as Topic; Female | 1972 |
Resumption of morphine self-administration by ex-addict rats: an attempt to modify tendencies to relapse.
Topics: Animals; Disease Models, Animal; Drinking Behavior; Humans; Male; Methadone; Morphine; Morphine Depe | 1972 |
Patterns of drop-outs from a methadone program for natcotic addicts.
Topics: Adult; Appointments and Schedules; Cooperative Behavior; Criminal Psychology; Employment; Evaluation | 1972 |
Evaluation of methadone maintenance treatment program.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Community Mental Health Services; Drug and Narcotic Cont | 1970 |
The natural history of narcotic drug addiction.
Topics: Adolescent; Adult; Age Factors; Drug and Narcotic Control; Female; Follow-Up Studies; Forensic Psych | 1970 |